LOCUS       NZ_CP060922            24944 bp    DNA     circular CON 24-MAY-2024
DEFINITION  Escherichia coli strain EC15 plasmid pEC15-NDM-5, complete sequence.
ACCESSION   NZ_CP060922
VERSION     NZ_CP060922.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15904659
            Assembly: GCF_022558845.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24944)
  AUTHORS   Ruan,Z.
  TITLE     Complete genome sequence of carbapenem resistant Escherichia coli
            isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24944)
  AUTHORS   Ruan,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-AUG-2020) Department of Clinical laboratory, Sir Run
            Run Shaw Hospital, School of Medicine, Zhejiang University, 3
            Qingchun East Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022558845.1-RS_2024_05_24
            Annotation Date                   :: 05/24/2024 04:04:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,173
            CDSs (total)                      :: 5,048
            Genes (coding)                    :: 4,789
            CDSs (with protein)               :: 4,789
            Genes (RNA)                       :: 125
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 94
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 259
            CDSs (without protein)            :: 259
            Pseudo Genes (ambiguous residues) :: 0 of 259
            Pseudo Genes (frameshifted)       :: 74 of 259
            Pseudo Genes (incomplete)         :: 188 of 259
            Pseudo Genes (internal stop)      :: 44 of 259
            Pseudo Genes (multiple problems)  :: 43 of 259
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP060922.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24944
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="EC15"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pEC15-NDM-5"
                     /geo_loc_name="China: Hangzhou"
                     /collection_date="2016-12-01"
                     /collected_by="Long Sun"
     gene            complement(join(24814..24944,1..850))
                     /locus_tag="H9202_RS25575"
                     /old_locus_tag="H9202_25315"
     CDS             complement(join(24814..24944,1..850))
                     /locus_tag="H9202_RS25575"
                     /old_locus_tag="H9202_25315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416498.2"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS5 family transposase"
                     /protein_id="WP_000019402.1"
                     /translation="MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFY
                     PKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTT
                     IMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPE
                     MHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAG
                     YQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRAKVEHPFRI
                     IKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH"
                     /name="IS5-like element IS5 family transposase"
     gene            1085..1897
                     /locus_tag="H9202_RS25580"
                     /old_locus_tag="H9202_25320"
     CDS             1085..1897
                     /locus_tag="H9202_RS25580"
                     /old_locus_tag="H9202_25320"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="WP_023408309.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQR
                     FGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQILNW
                     IKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHSLTF
                     AANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLG
                     DADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
                     /name="subclass B1 metallo-beta-lactamase NDM-5"
     gene            1901..2266
                     /gene="ble"
                     /locus_tag="H9202_RS25585"
                     /old_locus_tag="H9202_25325"
     ARG             1902..2263
                     /name="ble"
                     /gene="ble"
                     /gene_name="bleomycin binding protein Ble-MBL"
                     /tool="amrfinderplus"
                     /drug_class="BLEOMYCIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            2271..2909
                     /locus_tag="H9202_RS25590"
                     /old_locus_tag="H9202_25330"
     CDS             2271..2909
                     /locus_tag="H9202_RS25590"
                     /old_locus_tag="H9202_25330"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /GO_function="GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="WP_004201168.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVAG
                     ALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKPVW
                     KALPVASASDVARAAAYAGAADLILFDAKTPKGALPGGMGLAFDWSLLAGYRGALPWGL
                     AGGLNPTNVAEAIARTGAPLVDTSSGVESAPGVKDTDKITNFAFAVRLA"
                     /name="phosphoribosylanthranilate isomerase"
     gene            complement(2920..>3477)
                     /locus_tag="H9202_RS25595"
                     /pseudo=""
     CDS             complement(2920..>3477)
                     /locus_tag="H9202_RS25595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006399920.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocation (TAT) pathway signal
                     sequence domain protein"
                     /name="twin-arginine translocation (TAT) pathway signal
                     sequence domain protein"
     gene            complement(<3577..3951)
                     /locus_tag="H9202_RS25600"
                     /pseudo=""
     CDS             complement(<3577..3951)
                     /locus_tag="H9202_RS25600"
                     /inference="COORDINATES: protein motif:HMM:NF022853.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD
                     domain-containing protein"
                     /name="protein-disulfide reductase DsbD domain-containing
                     protein"
     gene            complement(3956..>4084)
                     /gene="cutA"
                     /locus_tag="H9202_RS25605"
                     /old_locus_tag="H9202_25340"
                     /pseudo=""
     CDS             complement(3956..>4084)
                     /gene="cutA"
                     /locus_tag="H9202_RS25605"
                     /old_locus_tag="H9202_25340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201171.1"
                     /GO_process="GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /name="cutA"
     gene            4149..4853
                     /locus_tag="H9202_RS25610"
                     /old_locus_tag="H9202_25345"
     CDS             4149..4853
                     /locus_tag="H9202_RS25610"
                     /old_locus_tag="H9202_25345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(4887..5243)
                     /locus_tag="H9202_RS25615"
     CDS             complement(4887..5243)
                     /locus_tag="H9202_RS25615"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="WP_004199403.1"
                     /translation="MGFPSPATDYQENRLSLDQHCNTGAPGVFFFRSDTYSFREGIKPG
                     ALLIVDFGGTPVDGSLVLCVLEQEFRIMRLRLHPKRCLQELDKLDNFRAIPDDDEDGLE
                     VRGVITHIVALLQS"
                     /name="S24 family peptidase"
     gene            complement(5246..5485)
                     /locus_tag="H9202_RS25620"
                     /old_locus_tag="H9202_25350"
     CDS             complement(5246..5485)
                     /locus_tag="H9202_RS25620"
                     /old_locus_tag="H9202_25350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001549892.1"
                     /translation="MPRHYEIDSAWRASIKREPNGRQTVTTEAFVSQLALINFHWSCRQ
                     ANQWIETYVTVFKDISTQEGENRTFMLFNPNGGR"
                     /name="hypothetical protein"
     gene            5587..6645
                     /locus_tag="H9202_RS25625"
                     /old_locus_tag="H9202_25355"
     CDS             5587..6645
                     /locus_tag="H9202_RS25625"
                     /old_locus_tag="H9202_25355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343765.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="WP_241408387.1"
                     /translation="MDEKSLYAHILNLSDPWQVKSLSLDENAGSVTVTIEIAENTRLAC
                     PTCGKSCSVHDHRHRKWRHLDTCQFTTIVEADVPRIMCPEHGCLTLPVPWAGPGSRYTL
                     LFESFVLSWLKISTVDAVRKQLKLSWNAVDGIMTRAVKRGLARIKKPLSARHMNVDEVA
                     FKKGHRYITVISDRDGRALALTDDRGTESLAGYLRTLTDGQLLAIKTLSMDMNAGYIRA
                     ARIHLPSAVEKIAFDRFHVAKQLGEVVDKTRQNEHPHLPVESRHQAKGTRFLWQYSDKW
                     MTESRQEKLMWLRAQMKLTSQCWALKELAKDIWNRPWSEERRSDWQRWLALAANSDVPM
                     MKNAAKTIGKGV"
                     /name="ISL3 family transposase"
     gene            complement(6670..9675)
                     /locus_tag="H9202_RS25630"
                     /old_locus_tag="H9202_25360"
     CDS             complement(6670..9675)
                     /locus_tag="H9202_RS25630"
                     /old_locus_tag="H9202_25360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143760.1"
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQVSVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGTLGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            9839..10396
                     /locus_tag="H9202_RS25635"
                     /old_locus_tag="H9202_25365"
     CDS             9839..10396
                     /locus_tag="H9202_RS25635"
                     /old_locus_tag="H9202_25365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001235713.1"
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            10579..11439
                     /locus_tag="H9202_RS25640"
                     /old_locus_tag="H9202_25370"
     CDS             10579..11439
                     /locus_tag="H9202_RS25640"
                     /old_locus_tag="H9202_25370"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     gene            <11589..11762
                     /locus_tag="H9202_RS25645"
                     /old_locus_tag="H9202_25375"
                     /pseudo=""
     CDS             <11589..11762
                     /locus_tag="H9202_RS25645"
                     /old_locus_tag="H9202_25375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343760.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(11851..12513)
                     /locus_tag="H9202_RS25650"
                     /old_locus_tag="H9202_25380"
     CDS             complement(11851..12513)
                     /locus_tag="H9202_RS25650"
                     /old_locus_tag="H9202_25380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549893.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001549893.1"
                     /translation="MTQTVPKGFVRAYLRASTTEQDATRALDTINTFAIERGLSICNYY
                     IENESGSKLERPELFRLLKDCQQNDILLVEDVDRLSRLVGEDWNTLKKMIRQKDIRVVA
                     VNVPTTWLASGHNDFDSRMFSAINDMLLDMLAAVARRDYEQRRERQQQGIARAKREGKY
                     KGRQVNQSRYDAINRLIASGSSWSQIQKVLGCSRATISKAVKQQTVNKMNHEPEGRE"
                     /name="recombinase family protein"
     gene            12894..13556
                     /locus_tag="H9202_RS25655"
                     /old_locus_tag="H9202_25385"
     CDS             12894..13556
                     /locus_tag="H9202_RS25655"
                     /old_locus_tag="H9202_25385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516402.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHDL
                     LSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVSDI
                     VVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDLDKL
                     LRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIGIL"
                     /name="division plane positioning ATPase MipZ"
     gene            13656..13940
                     /locus_tag="H9202_RS25660"
                     /old_locus_tag="H9202_25390"
     CDS             13656..13940
                     /locus_tag="H9202_RS25660"
                     /old_locus_tag="H9202_25390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001185481.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVAGKPKLMNFRL
                     PAYFEEILEAEAQRTGQSKTTVLKAALAAFDNLDENLKNHWLLESAKLG"
                     /name="hypothetical protein"
     gene            14146..14457
                     /locus_tag="H9202_RS25665"
                     /old_locus_tag="H9202_25395"
     CDS             14146..14457
                     /locus_tag="H9202_RS25665"
                     /old_locus_tag="H9202_25395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000469598.1"
                     /translation="MFIFRYIKTLINIYLLYIQPILGMFLIGIGLWGFYAPDEGTCTNL
                     NIELCAVSAIDVLKPAIFVFLGIITVAGWYFTELQPKLRGEGKYMKVKTGVKPEDFVK"
                     /name="hypothetical protein"
     gene            14493..14777
                     /locus_tag="H9202_RS25670"
                     /old_locus_tag="H9202_25400"
     CDS             14493..14777
                     /locus_tag="H9202_RS25670"
                     /old_locus_tag="H9202_25400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001043731.1"
                     /translation="MNKSWLEQQVQNEKLKKVQEEKKDGTIQKGLYRVRIKDKYRWDLW
                     ENDFRVVIAYSKDDAELKFTEMTGFNEHYYIESIEKIVLSDIEKILLEN"
                     /name="hypothetical protein"
     gene            complement(14798..15151)
                     /gene="ddp1"
                     /locus_tag="H9202_RS25675"
                     /old_locus_tag="H9202_25405"
     CDS             complement(14798..15151)
                     /gene="ddp1"
                     /locus_tag="H9202_RS25675"
                     /old_locus_tag="H9202_25405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_000877224.1"
                     /translation="MKYQVKEFINEKYSKAVNILKDNLKEHYHIFYGLRLSEILFPASE
                     YGSEMFFQEFEAINSVILPLVIFDLIDRKPIMVIGFGEVCGVDSLVDSGIEVVSLDGLS
                     DLLLVEKLTPLFN"
                     /name="ddp1"
     gene            complement(15339..15782)
                     /locus_tag="H9202_RS25680"
                     /old_locus_tag="H9202_25410"
     CDS             complement(15339..15782)
                     /locus_tag="H9202_RS25680"
                     /old_locus_tag="H9202_25410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001074369.1"
                     /translation="MAKIYEFPQGAERSKLKKEIIRERKKRLRETNGNPVIRHAKWFWF
                     YLRLATAGALHLVSVISLAVLGAFSKAIFWIGGMLCVVTWFHLERQFWTPQNFTIPVIV
                     TLWGLSLFATPLMELLNKKMPWYRLLVPDAKHTSTEATNDDQP"
                     /name="hypothetical protein"
     gene            complement(15791..16804)
                     /locus_tag="H9202_RS25685"
                     /old_locus_tag="H9202_25415"
     CDS             complement(15791..16804)
                     /locus_tag="H9202_RS25685"
                     /old_locus_tag="H9202_25415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348704.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001348704.1"
                     /translation="MRLLLSLDMKILRSSYLKVRGFLIKGCIVVLNYNLCGVMICLHRK
                     GYMRLIVKTVTGLTKVRHRNEVGVTLASLSLSAKRVLFLALCQIDTKEMLDDDILEVDA
                     DFFSKATSLDKYASYAALKEGAKVLSSTTLVLNRDDLKNLADELGILSSKNKIPDRLDL
                     NLTEFCAYYDHLATVRIKFTNTAKRYFSKLIGSENRYTTQVLKSVVLLNSVNSTNLYQV
                     IRKYYSQNSSKKSFDISVDDLKEEMGLYTIEEGEKKYKYPKYSFFVRDVINKSINEIIE
                     KTEINQLSFSVVGKKGRMAHMLRFEFSINEKSSSFSEDDMAFLEEFDKVVPPKKNK"
                     /name="replication initiation protein"
     gene            <17415..17567
                     /locus_tag="H9202_RS25690"
                     /old_locus_tag="H9202_25420"
                     /pseudo=""
     CDS             <17415..17567
                     /locus_tag="H9202_RS25690"
                     /old_locus_tag="H9202_25420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /name="DNA-binding protein"
     gene            complement(17745..17903)
                     /locus_tag="H9202_RS25695"
                     /old_locus_tag="H9202_25425"
     CDS             complement(17745..17903)
                     /locus_tag="H9202_RS25695"
                     /old_locus_tag="H9202_25425"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_152913118.1"
                     /translation="MRAITPLTPARPISDYQTMFSLSQLARELANGTPGQCETLARGAV
                     SARYEMR"
                     /name="hypothetical protein"
     gene            18157..18672
                     /locus_tag="H9202_RS25700"
                     /old_locus_tag="H9202_25430"
     CDS             18157..18672
                     /locus_tag="H9202_RS25700"
                     /old_locus_tag="H9202_25430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="WP_001025390.1"
                     /translation="MNIQEALNVFGLSGDLTEKDIKAAYKKAALKYHPDRNPLGAELMK
                     AVNAAFDFLMANIDKINQFQSTDENARYNYGEDLEKVLNTLSGLTGIVYEVIGNWVWIS
                     GETKEHKDILKEMGCKWASKKKQWFYRPEEHKSRWNRKEHSIEEIREMYGTAGKRKASG
                     WTRVEASA"
                     /name="DnaJ domain-containing protein"
     gene            18731..18967
                     /locus_tag="H9202_RS25705"
                     /old_locus_tag="H9202_25435"
     CDS             18731..18967
                     /locus_tag="H9202_RS25705"
                     /old_locus_tag="H9202_25435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000792381.1"
                     /translation="MKNKTITEAELINIFESYGAYICPDEIEVTAKECNENGSVLHRGL
                     NAEGWAHLFAKEEAYQQECEAQEAASDDGHFDE"
                     /name="hypothetical protein"
     gene            19027..19578
                     /locus_tag="H9202_RS25710"
                     /old_locus_tag="H9202_25440"
     CDS             19027..19578
                     /locus_tag="H9202_RS25710"
                     /old_locus_tag="H9202_25440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000662998.1"
                     /translation="MKEQKNFFERYKPVFEIVCRILGNGWRVNLLDDCQYRIKLTSPDF
                     KNYSIHIRMEKGRLVIIGSVDSRSWRSPYHTCTVSPERNPVEIAADIEKKILSDALDNV
                     DMAREYEQQLQQKREKKLILKGMLSRLVHLESWHGTLTGFKVENGLDGNVSERGDGYEM
                     VIRGLSVDQLIKVAGFIKQL"
                     /name="hypothetical protein"
     gene            19587..19856
                     /locus_tag="H9202_RS25715"
                     /old_locus_tag="H9202_25445"
     CDS             19587..19856
                     /locus_tag="H9202_RS25715"
                     /old_locus_tag="H9202_25445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001006717.1"
                     /translation="MNEVLSDRKNKGNVTYRIVVSEDATRLFIELEKLMKVRSKEADKK
                     TTKKIVFQKSFYYEEFSNVKDEIDDPILLKFYTDTIVKVQNHEF"
                     /name="hypothetical protein"
     gene            19846..20088
                     /locus_tag="H9202_RS25720"
                     /old_locus_tag="H9202_25450"
     CDS             19846..20088
                     /locus_tag="H9202_RS25720"
                     /old_locus_tag="H9202_25450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000008707.1"
                     /translation="MSFKPTPEEVKQARIKAGFTQQEAAERFGFTLSAWQAKETSGKTS
                     RGLAAGTYELLLLLADEHPDYQLVKREKNQDKVTK"
                     /name="hypothetical protein"
     gene            20182..20520
                     /locus_tag="H9202_RS25725"
                     /old_locus_tag="H9202_25455"
     CDS             20182..20520
                     /locus_tag="H9202_RS25725"
                     /old_locus_tag="H9202_25455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001099725.1"
                     /translation="MNTYVITFQALNTKKEKITCSAFVHSETLFLAVHSFEDKNRGRGY
                     VITSVSELLSEELTAKNSLKKNINFWFNECGLSKSEVINEVINWKNFAYTLKELEEAKN
                     EAIRELRS"
                     /name="hypothetical protein"
     gene            20595..20759
                     /locus_tag="H9202_RS25730"
                     /old_locus_tag="H9202_25460"
     CDS             20595..20759
                     /locus_tag="H9202_RS25730"
                     /old_locus_tag="H9202_25460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000004083.1"
                     /translation="MSERMLSAIQTVEKGGRPVFPLMPFSAFPEYMALLRKALEKKETK
                     ALIEKQEVL"
                     /name="hypothetical protein"
     gene            20756..21013
                     /locus_tag="H9202_RS25735"
                     /old_locus_tag="H9202_25465"
     CDS             20756..21013
                     /locus_tag="H9202_RS25735"
                     /old_locus_tag="H9202_25465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004199355.1"
                     /translation="MKKQEFLDFISAEQRRGAVRFSLGFNSKGEIVLHWTNEAGLRVWS
                     ILSGNRGKSPSRANRERMSNLRRWLHDARQGMEGDTPEAE"
                     /name="hypothetical protein"
     gene            21506..24523
                     /locus_tag="H9202_RS25740"
                     /old_locus_tag="H9202_25475"
     CDS             21506..24523
                     /locus_tag="H9202_RS25740"
                     /old_locus_tag="H9202_25475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490160.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element IS3000 family transposase"
                     /protein_id="WP_004199413.1"
                     /translation="MAFEERVQILSEAEQDELYGPPAFTSADQRFFFSLNDKELAIAKS
                     LRHRGQRYMLVVLLGYFKAKPVVLNPGFHQIKQDLKYVYQTVLPGPGCRPFNLTPKENE
                     RIYQRVFQLCNYQRWNVKDHGAALRDYLSQQARAWTAPRHLFDAANEYCSGQKIAIPAY
                     STLQKIISQVVGDEQEHMAAHLERAMSRGLKQALAELVNGTGPLPFRQLRQSARNFTGT
                     ELEKELIVYRHIQHWMPEVDLLLSTLSLSQKNLQHLAEKVDYYGAKLKRQTVGSQWLYL
                     LCYLQTRWQQALERIADGFVHHVRQTKQKAKDYAQEAVFKDWQKAAKNVSKAAEVLHLF
                     IDDSIDLQLPFATVRQQALSLLTKRDLESVCLFLNEQRRSVDEAMWQYCDEKESLRKGL
                     LRELFLCLRFEGCDGTQHLAAALAKTQNELNGQDAQLQTADTRLLSKKSREFLLDGEGN
                     ILIDRYEWFLYQQIPDRLNGQLTLPDITKYRALDADLIDGEHWRKNKYTLLQQSHFTKL
                     AEEPEKLIKQMAMELDTRLYEVGEYLEQEDNRNIILRNPQGKRFWRLPSASKHHLVNNP
                     FFQQIPTTGIADVLRMVDRDTGFIDCFAHVLGSQSRSRSHEYDLLAILVGNATNQGIYG
                     MAQISDRTYDQLSTIQANYLRLETLNAANDNINNATAKLPIFRYYNIQEDVIHASADGQ
                     KFEARRETFKTRYSSKYFGTQKGVSAMTLIANHAAINARVIGANEHESHYIFDLLMSNT
                     SDIIPDVLSTDTHGVNHVNFALLDLFGYQFAPRYAQVGKVINDMFDVKEDKEHRIQLCL
                     KKPINTHRIAQHWDTIQRIAVSLKQRKTTQATLVRKLSEYKRNHPLLEALTEYNRLVKA
                     NYLLCYIDDASLRNYVQRALNRGEAYHQLRRAVSSVNGDQFRGSSDEEIQLWNECARLV
                     TNAIVYFNSRILSQLLTSFEYQGDTKRIDIVKQASPVAWHNINLKGTYHFELSEKLPDL
                     EELMRSIEGYLPVSEK"
                     /name="Tn3-like element IS3000 family transposase"
     ARG             10580..11436
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1086..1894
                     /name="blaNDM-5"
                     /gene="blaNDM-5"
                     /gene_name="subclass B1 metallo-beta-lactamase NDM-5"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(15792..16663)
                     /name="IncX3"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gcttgatgat gcgaaatggg tgctccacct tggcccggat gctggctttc atgtattcga
       61 tgttgatggc cgttttgttc ttgcgtggat gctgtttcaa ggttcttacc ttgccggggc
      121 gctcggcgat cagccagtcc acatccacct cggccagctc ctcgcgctgt ggcgcccctt
      181 ggtagccggc atcggctgag acaaattgct cctctccatg cagcagatta cccagctgat
      241 tgaggtcatg ctcgttggcc gcggtggtga ctaggctgtg ggtcaggcca ctcttggcat
      301 cgacaccaat gtgggccttc atgccaaagt gccattgatt gcctttcttg gtctgatgca
      361 tctccggatc gcgttgctgc tctttgttct tggtcgagct gggtgcctca atgatggtgg
      421 catcgaccaa ggtgccttga gtcatcatga cgcctgcttc ggccagccag cgattgatgg
      481 tcttgaacaa ttggcgggcc agttgatgct gctccagcag gtggcggaaa ttcatgatgg
      541 tggtgcggtc aggcaaggcg ctatccaggg ataaccgggc aaacagacgc atggaggcga
      601 tttcgtacag agcatcttcc atcgcgccat cgctcaggtt gtaccaatgc tgcatgcagt
      661 gaatgcgtag catggtttcc agcggataag gtcgccggcc attaccagcc ttggggtaaa
      721 acggctcgat gacttccacc atgttttgcc atggcagaat ctgctccatg cgggacaaga
      781 aaatctcttt tctggtctga cggcgcttac tgctgaattc actgtcggcg aaggtaagtt
      841 gatgactcat gatgaaccct gttccatggc tccagatgac aaacatgatc tcatatcagg
      901 gacttgttcg caccttcctt agagaaattt gctcagcttg ttgattatca tatggctttt
      961 gaaactgtcg cacctcatgt ttgaattcgc cccatatttt tgctacagtg aaccaaatta
     1021 agatcatcta tttactaggc ctcgcatttg cggggttttt aatgctgaat aaaaggaaaa
     1081 cttgatggaa ttgcccaata ttatgcaccc ggtcgcgaag ctgagcaccg cattagccgc
     1141 tgcattgatg ctgagcgggt gcatgcccgg tgaaatccgc ccgacgattg gccagcaaat
     1201 ggaaactggc gaccaacggt ttggcgatct ggttttccgc cagctcgcac cgaatgtctg
     1261 gcagcacact tcctatctcg acatgccggg tttcggggca gtcgcttcca acggtttgat
     1321 cgtcagggat ggcggccgcg tgctgttggt cgataccgcc tggaccgatg accagaccgc
     1381 ccagatcctc aactggatca agcaggagat caacctgccg gtcgcgctgg cggtggtgac
     1441 tcacgcgcat caggacaaga tgggcggtat ggacgcgctg catgcggcgg ggattgcgac
     1501 ttatgccaat gcgttgtcga accagcttgc cccgcaagag gggctggttg cggcgcaaca
     1561 cagcctgact ttcgccgcca atggctgggt cgaaccagca accgcgccca actttggccc
     1621 gctcaaggta ttttaccccg gccccggcca caccagtgac aatatcaccg ttgggatcga
     1681 cggcaccgac atcgcttttg gtggctgcct gatcaaggac agcaaggcca agtcgctcgg
     1741 caatctcggt gatgccgaca ctgagcacta cgccgcgtca gcgcgcgcgt ttggtgcggc
     1801 gttccccaag gccagcatga tcgtgatgag ccattccgcc cccgatagcc gcgccgcaat
     1861 cactcatacg gcccgcatgg ccgacaagct gcgctgagcc atggctgacc acgtcacccc
     1921 caatctgcca tcgcgcgatt tcgatgtgac agaggcgttt tatgcgaagc tgggctttgc
     1981 gacgagttgg aaggatcgcg gctggatgat cctgcagcgc ggcggtttgc agctcgaatt
     2041 cttcccctat cctgacctcg acccagctac gagctcgttc ggctgttgcc tgcggttgga
     2101 tgatctcgat gccatggtgg cattggtgaa cgcggcggga gccgaggaaa aaagcaccgg
     2161 ctggccgcgc ttcaaagctc cgcaactgga ggcgagcggc ctgaggatcg gctacctgat
     2221 cgatcccgac tgcacgctgg tgcggctgat ccagaacccc gactgaccgc atgcccgcga
     2281 aaatcaagat ttgcgggatc agcacacccg aggcgctcga tgcgaccatc gcggcgcggg
     2341 cggactatgc cgggttggtg ttctatccag cgtcgccccg tgcggttacg tcgaatgtcg
     2401 cgggcgcttt gacatcgcgc gcagctggcc agatcgccat ggtcggtttg ttcgtcgatg
     2461 cggatgatgc tgtcatcgcc gacgcactgg tggcagccaa gctgaacgcg ctgcagctgc
     2521 acggttcgga atcgcccgaa cgcgtggccc agttgcgcgc gcggtttggc aagccggtgt
     2581 ggaaggcgct gcccgtcgcc agcgccagcg atgtcgcacg cgccgcagcc tatgccgggg
     2641 cggcggactt gatcttgttc gacgccaaga cccccaaagg cgcgctgccc ggcggcatgg
     2701 ggttggcgtt cgactggtcg ctgctggccg gatatcgcgg tgccttgccg tgggggctgg
     2761 caggcgggct aaatccgacg aatgttgccg aggcgattgc gcgcaccgga gcgccgctgg
     2821 tcgatacctc cagcggcgtc gaaagcgcgc cgggcgtcaa ggataccgac aagattacca
     2881 atttcgcctt tgcggtgcgc ttggcctaaa tcgcgtcgat caataggcgt cgttcagcgc
     2941 aaagatcggc ttgcgggtgc gccactgccc tcgggtgaag tcgggaaaat ctaacgtgcg
     3001 attgccctca gcaatcgatt gttccgacag aggcgtgatc gcgctccagg ccagcgcgtc
     3061 gtaaatgtcg attggcatcg gggccttggc cttcagcgcc tcgacaaaag cgtggatcac
     3121 gaaccagtcc atcccgccat gcccggcccc tgccgccaga tcggcgtagc gtttccatag
     3181 cgggtgatcg tatttcgcaa accagccctc ggcaggctcc cagcggtgcg gctgtgggct
     3241 cttgccctcc agatagatcg acttgttgac gtccatccac agcccctcgg tgccttgcac
     3301 ccgaaagccg agagaatagg ggcgcggcag cgaggtgtcg tggcacagca tgatcgtttc
     3361 accattagtg cagccgatca tggtgttgac cacatcaccc agtgcgaatt tcacctcggc
     3421 gttgggatga tcggcagagc cgttcttgac gacataatca tgcagcccgc gcgccttaca
     3481 gccgaagccg ccagcgcccg cttcgcccgg caacgcgacc ttcagggtgc gggtctgcgg
     3541 cgggtagcac acgccggcat cggcgcagcc ctggtacttc acggtcaggg tggtcgcgct
     3601 cgcgccggcc gcgggcgtgc cggtgagggt gccgagcaat tccttgcggt aggtttcgac
     3661 gtcgccgaag aattcgtcgc ggtaggcctt gcccttcggc agcgccatgg tcgcgccggt
     3721 gaaggcggca tcggccttga ccgaggtgcg gtgccggtac aggtaatagc cgtcggcgat
     3781 ccgccagcgc acctcgatgc ggtccggcgc ggtggcctgc gcggacagga cgaagacctc
     3841 gtcgaccggc ggcagttcga agtcctgggc gacggccgag gtcgcgggca gcgcaagcag
     3901 cagggcgagc ccggccagcc agcggcgcag gcggatcgtg gatgcggtca ttggctcagt
     3961 ttaccggtcg gctctcggcg gccagccatt gcaggtattc gggcaggccg gacgcggctt
     4021 cgaccgcgag cagctccggg agttcgtagg gatgcagttg gcgcaggcgt tcctgcaggg
     4081 cggggggcac tgttgcaaat agtcggtggt gataaactta tcatcccctt ttgctgatgg
     4141 agctgcacat gaacccattc aaaggccggc attttcagcg tgacatcatt ctgtgggccg
     4201 tacgctggta ctgcaaatac ggcatcagtt accgtgagct gcaggagatg ctggctgaac
     4261 gcggagtgaa tgtcgatcac tccacgattt accgctgggt tcagcgttat gcgcctgaaa
     4321 tggaaaaacg gctgcgctgg tactggcgta acccttccga tctttgcccg tggcacatgg
     4381 atgaaaccta cgtgaaggtc aatggccgct gggcgtatct gtaccgggcc gtcgacagcc
     4441 ggggccgcac tgtcgatttt tatctctcct cccgtcgtaa cagcaaagct gcataccggt
     4501 ttctgggtaa aatcctcaac aacgtgaaga agtggcagat cccgcgattc atcaacacgg
     4561 ataaagcgcc cgcctatggt cgcgcgcttg ctctgctcaa acgcgaaggc cggtgcccgt
     4621 ctgacgttga acaccgacag attaagtacc ggaacaacgt gattgaatgc gatcatggca
     4681 aactgaaacg gataatcggc gccacgctgg gatttaaatc catgaagacg gcttacgcca
     4741 ccatcaaagg tattgaggtg atgcgtgcac tacgcaaagg ccaggcctca gcattttatt
     4801 atggtgatcc cctgggcgaa atgcgcctgg taagcagagt ttttgaaatg taaggccttt
     4861 gaataagaca aaaggctgcc tcatcgctaa ctttgcaaca gtgccacaat gtgcgtaatg
     4921 acccccctga cctccaaccc gtcctcatcg tcatcaggta tagccctgaa gttatccagc
     4981 ttatcgagtt cctggagaca ccgcttgggg tgtagtcgca atcgcatgat cctgaattct
     5041 tgttccagga cacagagcac caaagacccg tcaacgggcg tgcccccaaa atctactatg
     5101 agcagcgcac caggctttat cccttcccgg aaagagtagg tatcacttcg aaaaaagaat
     5161 actcccggcg ctcctgtatt acagtgctga tcgagtgaca gcctgttttc ctggtagtcg
     5221 gttgctggcg atggaaaacc catttttaac ggcctccgtt ggggttaaaa agcatgaatg
     5281 tccggttctc tccttcctga gtggaaatgt ctttaaaaac ggtcacgtag gtttcaatcc
     5341 actgatttgc ttggcgacaa ctccagtgaa aattaatcag cgcaagctgg ctgacaaagg
     5401 cttctgtcgt aactgtctga cgaccgttcg gctcacgctt aatgctcgca cgccaggctg
     5461 agtcaatttc atagtgtcta ggcatgaaaa acctccgatc aatatagctg tatgcatatg
     5521 ggtcttccct tgttgtggtg gctgaaggca tgataatggt gtatttaatc gccagaggtc
     5581 accgccatgg acgaaaagtc cctctacgct catattctca acctgtccga tccgtggcag
     5641 gtaaagtccc tttctctcga tgaaaatgcc ggttctgtta ctgtcactat tgagatcgct
     5701 gaaaacaccc ggctagcctg tccgacctgc ggtaaatcct gttctgttca cgatcaccgt
     5761 catcgtaaat ggcgccatct tgatacctgc cagttcacca ctattgttga agccgatgtt
     5821 ccacgaatta tgtgtccgga gcatggctgc ctgacgttgc ctgttccgtg ggctggcccc
     5881 ggaagccggt atacgttgct attcgaatcg ttcgttctct catggctgaa aatcagcacc
     5941 gttgatgctg tcaggaagca acttaagctc agttggaatg cggttgacgg cattatgacc
     6001 cgggcagtta agcgaggtct tgcccggata aaaaagccat tatccgcccg tcatatgaat
     6061 gtggatgagg tcgcctttaa aaaaggacat cgttacataa cggtgatctc cgatcgcgat
     6121 ggtcgggcgc tggccttaac ggatgatcgc ggcacagaga gtcttgccgg ctatcttcgc
     6181 acgctcactg atgggcagtt gctggctatc aaaacgctct caatggacat gaacgcgggc
     6241 tatataagag cagcgcgtat ccacttaccc agtgcggttg agaaaatcgc ctttgaccgc
     6301 ttccatgtgg cgaagcaact gggcgaggta gttgataaaa cccgtcagaa tgaacatccg
     6361 cacctccctg ttgaaagccg acaccaggca aaaggaaccc gcttcctgtg gcagtacagc
     6421 gataagtgga tgaccgaatc ccggcaggaa aagctgatgt ggctgcgtgc acagatgaag
     6481 ctgacgagcc agtgctgggc gctgaaagag ctggcaaagg atatctggaa caggccatgg
     6541 agcgaggaaa gacggagtga ctggcagaga tggttggcgc tggcggctaa cagtgacgtt
     6601 cccatgatga aaaatgccgc gaaaacgata ggaaaagggg tctgacgctc agtggaacga
     6661 aaactcacgt taagcaacgt tttctgcctc tgacgcctct tttaatggtc tcagatgtcc
     6721 tttggtcacc agttctgcca gcgtgaagga ataatggccg agcatattga tatgtccgtg
     6781 gcaaagcggg gagaggcgtg cgatatcttc atcattcagt gtttcaccct gcgcccggag
     6841 atgatccagg gctgcctgca tataaatagt gttccataac acgacggcgt tagtgaccag
     6901 ccccagtgtg cccagttgat cttcctgacc gtcggtatat cgttttctta tctcaccttt
     6961 ttgaccgtga cagatggctc tggcaacggc atggcgactt tctccccgat taagctgggt
     7021 cagaatgcgc cggcggtaat cttcatcatc aatataatta agcagataca gcgttttgtt
     7081 gatgcgcccc acttcaatga ttgcctgagt cagtccggaa ggacgttcac ttttcagcaa
     7141 tgaacggacc agcactgaaa cctgtacttt gcccagcttc agggagccag cggtccggat
     7201 catttcgtcc cactgaagga ctatttttcg gggatctgat tgccctctgg caatatcatt
     7261 cagcacgcca tagtcggcat catggtccat tcgccagaaa accgaagcac cggcatcagc
     7321 caggcgtgga gaaaactggt atcccagcag ccagaaaagg ccaaagacaa gttcgctggc
     7381 acctgctgta tcggtcataa tttcggttgg attcagcccg gtctcctgtt ccagaagacc
     7441 ttccagcaca aagatagagt ccctcagcgt ccccggtata acgatgccat gaaagccgga
     7501 atactgatcg gacacaaagt tgtaccaggt gatccctctg ttattaccaa agtatttgcg
     7561 gttcggtccg gcattgattg ttctgactgg cgtaacaaag cgcattccat ctgcagatgc
     7621 cacttctcct ccaccccata tctgtgccag tggcagcgtt gcctgaaaat caaccagtct
     7681 ggcattagcg ctggtgatag tttcagcccg cagatagttc gcttttgtcc agttcagccg
     7741 gtgtcgggtc agtgcaggaa catttgatct gatcagtggt tccagaccga tattgcaggc
     7801 ttcagccatc agcacggcgc tgatgctgac gggcagatca tcaactctgg cactggcttc
     7861 actagcatgg aaaaactcat cagcaaatcc ggtatgggcg ttaatttcga gcagcaactc
     7921 cgttaaatcc accggaggga gtagatcact gatcattttg ctcagtcgtt tcagactgtc
     7981 cggctcatca agactggcga ggggagaaat tgtcaaccgg ggcttcgggc cagaaacatc
     8041 gagttcgaca gcctcatttt cgcaaagacg tgcagcaacc tgtctgtaac gactatcaag
     8101 ctgatgaccc agagatttta ttgcttcctg cgggtctgtc gggtgcccca aagaacgata
     8161 aaccttaatc cggtttgcct gccagtcagc accctgtagt aatcttgcac gaggatctcc
     8221 ccaccggtta ctgccggtaa cgtagacatc cctccgcctc agactatcct gcagtttact
     8281 gagaaagcag agcgtgtatc ccctgcgggt gatatgtttt tccttgttaa tcaccagccg
     8341 tttccatgac cgactgataa tttccgttgg tgcgtcgtca aaaaactgcc gccgtgagct
     8401 gaactcccgg ctgaggtagt cacaggcatt cagagtggta accccggcag gtgcggatga
     8461 aaatttaacg gtattcagca gatggggcag gaaacgacga acgcgcccgt actgctccac
     8521 catttcttca tgaaaattat cgtctgaggg ccgggcaatt tcacggacaa gcgtgatgat
     8581 ttcagccagc ttttgccttg ggatgtagct gaacacctca gcacgaatcg attcgtccgg
     8641 tgtttcttct ttcagcaggt acgaacatgc gctggcgagc gccaatgcag atttatccag
     8701 atccttcagc gagcggagcc gttttttctg cccaatcttt ctggcgtcac ggatgataac
     8761 ggccagcatg gcgtccagaa cgtccaatgc atcatccagc gccagcgttt cccatgcaag
     8821 gacaaaggca accagaaccg ccatcctttt ctgcggtgac atcctggcaa tattgaacac
     8881 cgaagtcata ccagcataac gtgcgagatt tttcaggcgc acagccggga gtgtactcag
     8941 gttttcagca tgcaggccaa aatcgttcag agttttccag cgttcaattg cttcattaaa
     9001 cgccggacca ctgatggtca cagggccctt tttcagtgat tccagtaaag acaggcggct
     9061 gcaatcagtt ggccccagca gcatctccag ctgtgaacgc tgttcggctg acggtatcag
     9121 tgccagtttg ttccacaggc gcaacgtcgc cttttccctt acctctgaaa tcaaccgggt
     9181 cagcgtagtg gctccgggga gaataatacg atgttgcata agccaccctg tcgccagatc
     9241 gaaaagcagg ccaggacgtt cgttgcttat ccagctccgg gtatataaaa gacgggtaag
     9301 gcgaaatgtc cagggccagg caaattcacg atactgatag tgctgacgta tcagcgctgc
     9361 atgctcacgg cgggtatttt ccctctgacc gtattctgca agaacggtga tatcacgaat
     9421 cccgagctgt ctggcggtaa aatgccggac gccggaagga atatgattca tatcggtgag
     9481 gaaggtgccc agaaaacgga cacatccaat ttgcagggca atgcccagac ggttgtgatc
     9541 acctctgctt tttccgataa attccttgtc tgcttcatca aggtgaaaat atcgtgccag
     9601 ctgaagctca tccggttcac cggtgaatct gccatagctt tcagtctgct cagtggtcag
     9661 aaagtcaacg ggcatatcgg cctccctgcc tgacgggcat ttagtaacat ttttccaacc
     9721 gtacgaaatg ttataaatta tcggacatcg taaaactgtt acattaatat gtctattaaa
     9781 tcgtaaattt gtaataatag acatgagttg tccgatattc gatttaaggt acatttttat
     9841 gcgacttttt ggttacgctc gggtctcaac cagtcagcag tctcttgatc ttcaggtcag
     9901 agcactcaaa gacgcaggtg tgaaagcaaa ccgtatattt accgataagg catccggcag
     9961 ttcaacagac cgggaagggc tggatttgct gaggatgaag gtggaggaag gtgatgtcat
    10021 tctggttaag aagctcgacc gtcttggccg cgacactgcc gatatgatcc aactgataaa
    10081 ggaatttgac gctcagggcg tggcagtccg gttcattgat gacgggatca gtaccgacgg
    10141 tgatatgggg caaatggtgg tcaccatcct gtcggctgtg gcacaggctg aacgccggag
    10201 gatcctagaa cgcacgaatg agggccgaca ggaagcaaag ctgaaaggaa tcaaatttgg
    10261 ccgcaggcgt accgtggaca ggaacgtcgt gctgacgctt catcagaagg gcactggtgc
    10321 aacggaaatt gctcatcagc tcagtattgc ccgctccacg gtttataaaa ttcttgaaga
    10381 cgaaagggcc tcgtgatacg cctattttta taggttaatg tcatgataat aatggtttct
    10441 tagacgtcag gtggcacttt tcggggaaat gtgcgcggaa cccctatttg tttatttttc
    10501 taaatacatt caaatatgta tccgctcatg agacaataac cctggtaaat gcttcaataa
    10561 tattgaaaaa ggaagagtat gagtattcaa cattttcgtg tcgcccttat tccctttttt
    10621 gcggcatttt gccttcctgt ttttgctcac ccagaaacgc tggtgaaagt aaaagatgct
    10681 gaagatcagt tgggtgcacg agtgggttac atcgaactgg atctcaacag cggtaagatc
    10741 cttgagagtt ttcgccccga agaacgtttt ccaatgatga gcacttttaa agttctgcta
    10801 tgtggtgcgg tattatcccg tgttgacgcc gggcaagagc aactcggtcg ccgcatacac
    10861 tattctcaga atgacttggt tgagtactca ccagtcacag aaaagcatct tacggatggc
    10921 atgacagtaa gagaattatg cagtgctgcc ataaccatga gtgataacac tgctgccaac
    10981 ttacttctga caacgatcgg aggaccgaag gagctaaccg cttttttgca caacatgggg
    11041 gatcatgtaa ctcgccttga tcgttgggaa ccggagctga atgaagccat accaaacgac
    11101 gagcgtgaca ccacgatgcc tgcagcaatg gcaacaacgt tgcgcaaact attaactggc
    11161 gaactactta ctctagcttc ccggcaacaa ttaatagact ggatggaggc ggataaagtt
    11221 gcaggaccac ttctgcgctc ggcccttccg gctggctggt ttattgctga taaatctgga
    11281 gccggtgagc gtgggtctcg cggtatcatt gcagcactgg ggccagatgg taagccctcc
    11341 cgtatcgtag ttatctacac gacggggagt caggcaacta tggatgaacg aaatagacag
    11401 atcgctgaga taggtgcctc actgattaag cattggtaac tgtcagacca agtttactca
    11461 tatatacttt agattgattt aaaacttcat ttttaattta aaaggatcta ggtgaagatc
    11521 ctttttgata atctcatgac caaaatccct taacgtgagt tttcgttcca ctgagcgtca
    11581 gaccccgaaa aaggctgtac gggatcctga atgcgatgcg acacagtgtc tcaaacggaa
    11641 atgcggaggc acttaacagc aagatcaggc tgctgaggat aaaagccagg ggataccgaa
    11701 accgggagcg ctttaaactg ggggtgatgt tccactacgg aaagctgaat atggcgttct
    11761 gagccttccc accatgatcg gggaagaccc atgcatatac agtataaaga atcagtttta
    11821 ttcttcaaca cactgtttat tatgttgtaa ctactcccta ccttcaggtt catggttcat
    11881 tttgttaacg gtctgttgct tcacagcttt gctgatagtc gcccggctac aacccagcac
    11941 tttttgaatc tggctccagg agctgccgct cgcaatcagc ctgtttatgg cgtcatagcg
    12001 agactgatta acctggcggc ctttatactt cccttccctt ttcgccctgg cgatcccctg
    12061 ctgctgccgt tcccggcgct gttcatagtc tcgcctggcg acggcggcca gcatatccag
    12121 caacatatcg tttatggccg aaaacattcg gctgtcaaaa tcattgtgac ccgatgcgag
    12181 ccaggttgtc ggaacgttga cggccacaac ccggatatct ttctgccgga tcattttctt
    12241 cagtgtgttc cagtcctccc ctaccaggcg tgaaagcctg tccacatcct ctaccagcaa
    12301 gatatcgttt tgctgacaat ctttcaggag ccggaacaac tcagggcgtt caagcttaga
    12361 acctgattca ttttcaatgt agtagttaca gatgctcagg ccgcgctcga tggcgaaggt
    12421 atttatcgtg tccagggcgc gtgttgcatc ctgttcagtc gtggatgcgc gtaagtaagc
    12481 tctgacaaag cctttcggta ctgtttgagt cattataggg aaccagttca ttttgagtta
    12541 accagacaca cccatacagt acccatttca gttggttcag ggaaggcaca ctcaaaaaga
    12601 accagcaaac agaccccagc cctatagtga caacgtcaca ctaaaaattt acaacataaa
    12661 gatgatgtaa agacacacca agatttacac cataaagcgc acataaagac acagcaacat
    12721 ttaccatgta aagacaccat aaagataaat atatctttat ttgtgcttta catggtaaag
    12781 ccattgcatt ataaagacac tgtaaagaca aaagtatctt tacgaaaaac acaccatgta
    12841 aagacattca tatctttaca tgagctttac aacataaaga gagggattct gaaatgggta
    12901 aaatcttgct tgtcgtatca gataaaggtg gggtaggcaa aagcacctac gtggctaaca
    12961 caggctcaat gctggtcaac aaaggtaagt cggtaattat cctgaagaca gataaaaacc
    13021 acgatctgtt gagctggaac gaaaagcgga cagataacgg cttactcact atcccggttc
    13081 acgcagctta cggaaacgtc agcaacgaaa ttaagcgcct tagtaagctg tgtgaagttc
    13141 tcattgtcga ttgccccggc cacgacagcc aggagttccg tagcgccctg acagtatcag
    13201 atatcgtggt gacactggtt aagccgtcct ctgatttcga aagcgaaaca ctgaccagtg
    13261 ttacagagaa aatccgcacc gctcagaaag ctaacgcagc tctggaaccg tgggtgctgt
    13321 tcaccagaat caactcagcg aaaccccgcc acagaaaagc ggccattgat ctggataaat
    13381 tactgcgttc ggacaacatc tggattcaac ctctgaaaac ccggatatcc gagctggatg
    13441 tgtatgaaag cgcctgtaat gaaggggcag gggtacatga cgttagccgg gcatcgagcc
    13501 tttcaacagc gaaagcacag attgaacttg tggcacagga aattggcatt ttatagaaat
    13561 atcaacaata ttcatcgaaa tctttacatt gtaaatacac cataaagata ctatgatatt
    13621 tacaattaat gcataccgta caaggggaaa ttttcatggc tttaaaacta aaccgcccga
    13681 acatcgatga atctcagcaa ccagcaacaa acgcagaaac cgcgcgtttt atctccggcg
    13741 ctaccagagc gcctgtagcg ggtaaaccaa agttgatgaa cttcagactg ccagcgtact
    13801 ttgaggagat cctggaagcg gaggcgcaga gaacaggcca gagcaagaca accgttctaa
    13861 aggcagcgct ggccgcattc gataacctgg acgagaacct gaaaaaccac tggctgcttg
    13921 aatctgcaaa attagggtag cgttatggct aagaaaaaga gatatgttgt gatggttaga
    13981 gataaaccaa atacagcggc aatcagcgat tattagcctg gttagtatgg ttcgctaaca
    14041 ggcataataa ggccgttgcc tatgactgcg gagaatggat tgtcgaacca tcacattggt
    14101 taagaattgg aaatccaaaa tagaaagaaa cctaaggaaa gaaaaatgtt catattcaga
    14161 tatattaaaa ctcttattaa tatctacttg ttatacatcc aaccgatatt ggggatgttc
    14221 cttataggta taggcttatg ggggttctat gcacctgatg agggaacttg tactaatctc
    14281 aatattgagt tatgcgctgt atcagctatt gatgttctga agcctgctat ttttgtattt
    14341 ttaggcatta ttaccgttgc cggatggtac tttaccgaac ttcagccgaa gctaaggggg
    14401 gagggcaagt atatgaaggt aaaaacaggt gtaaaaccgg aagatttcgt taagtaaaaa
    14461 ccgagcctaa agacgttaac cgtgggggat ttatgaataa atcatggctt gaacaacagg
    14521 tgcaaaatga aaaattaaaa aaagtacagg aagagaaaaa agatggcact atccaaaaag
    14581 gattgtacag ggttcgtata aaagacaaat acaggtggga tttgtgggaa aatgatttca
    14641 gagttgttat tgcttattcg aaagatgatg cagagctaaa atttacagaa atgacaggtt
    14701 ttaatgagca ttactatata gaaagcattg aaaaaatagt gctttcagat atagaaaaaa
    14761 tcttactgga aaactgaaaa gatagttatc cagaggttta gttaaataat ggcgtcagtt
    14821 tttcaaccag tagcagatcg cttaaaccgt ctaaagaaac aacttctata ccagaatcaa
    14881 caagtgaatc aactccacat acttcaccga agccgataac cataatcggc tttcggtcta
    14941 tcaaatcaaa aatcaccaaa ggcaatatta cactgttaat cgcttcaaac tcctgaaaaa
    15001 acatttcaga gccgtattcg ctggcaggaa aaagaatctc acttaatctc aaaccataaa
    15061 aaatatggta gtgttcttta aggttatcct ttaaaatatt aacagcctta gaatattttt
    15121 cgttaataaa ctctttaacc tgatatttca taactctctc caacaagaac cgactgtagg
    15181 tcaccgggca aacgttgcgg aatggcgtca gagacgtcat tttgcggcgt ttgccctatc
    15241 ctgcatcgca gtgaaaagaa ctcgcctcgt gcgctatgat taaccgatga taaaaggctg
    15301 aaagaagcac tgcaagccga ctggataaca ttgttgcttc acggctgatc atcattggtt
    15361 gcctcagtgc tagtgtgctt tgcatcagga accagaagac gataccacgg catttttttg
    15421 ttaagcagct ccatcagggg agtggcaaac aaactcaatc cccacagcgt tacgattact
    15481 ggaatcgtga aattttgcgg cgtccagaac tggcgctcaa ggtggaacca tgtaacaaca
    15541 cagagcattc caccaatcca gaaaatagct ttactgaaag cccccaggac tgccagagaa
    15601 ataacagaga ctaaatgcag tgcgccagcc gtagcaagac gtagataaaa ccagaaccat
    15661 ttagcgtgcc ggataaccgg gttaccgttc gtttctcgca atcgtttttt acgttcccgg
    15721 atgatttctt ttttcagctt acttcgttcg gctccctgcg gaaactcata tattttagcc
    15781 atgttttgcc tcacttattc ttttttggtg gaacgacttt gtcaaactcc tctaaaaatg
    15841 ccatatcatc ttccgaaaag gatgaggatt tttcatttat actaaactca aatctaagca
    15901 tgtgagccat tctccctttt ttcccaacaa cagagaaaga taactgattt atttccgttt
    15961 tctcaattat ctcattaatg cttttattga taacatcacg aacaaaaaat gagtatttag
    16021 gatacttata tttcttctcc ccttcctcaa tagtataaag tcccatttcc tcttttaaat
    16081 catccacgga tatatcaaaa gatttttttg aactattctg actgtaatat ttcctaatga
    16141 cttgataaag gtttgttgag tttacactgt tcaacaacac aactgatttc aatacctgag
    16201 tggtatatct attttcagaa ccaatcaact tagaaaaata tcgcttagct gtatttgtga
    16261 attttatccg tacagttgca agatgatcgt aataggcaca gaattctgtt aagtttaaat
    16321 ccaagcgatc aggtatttta ttcttagatg atagtatccc aagttcatca gccaaatttt
    16381 ttaaatcatc tctgtttaaa actaacgtag ttgaagaaag aactttagct ccctctttca
    16441 gagctgcata agaggcatat ttatctaaag aagtagcttt tgaaaaaaag tcagcatcaa
    16501 cctccaaaat atcatcatct aacatttcct ttgtatcaat ctggcaaaga gccagaaaaa
    16561 gcactctttt tgctgaaagg gaaagggatg caagagttac cccaacttca tttctatgtc
    16621 taactttcgt taatcccgtt actgtcttca cgataagcct catataacct ttcctatgta
    16681 ggcaaatcat aaccccacaa aggttgtaat tcaagacaac aatacaacct ttaattaaaa
    16741 aacctctcac ctttagatat gaagatctga ggatcttcat atctaaagat agcaacaacc
    16801 gcatgtttca cttgatgttc agtcaaactg tggaaaccgt taaaaatctt ctcaccttac
    16861 gtgaaaaatc ctctcatctt tagtgaaaaa tctaactacc ttaacttaaa aatcttctca
    16921 ccttacgtga aaaatcctct caccttacgt gaaaaatcct ctcaccttta gcaatttttt
    16981 tccataattt tcaggtaatt gaagcgagct aagtttttaa gtttttaaga tcaagaagaa
    17041 aatataaggc ttttaatgca cagcgtctgt ggataactca gcataaatcc agaggataga
    17101 tccgtctggc ctccctgagc actgcaccac caaaaattga gcaaatatta accttagcgc
    17161 gtaagtgctc tattgaaacc ccgtggaaat tccgcttcct cgctcactcg cgggcttcgc
    17221 cctgtcgttc ggctgcggcg agcggtgtaa tctctctaaa agatccagac gggatccttt
    17281 tccgatccaa ttcttaaatg ctctcaaaag ccctcagagg cgttttaacc gctttaaccc
    17341 ggtcatggtt caacggagcg ggtaaaatgc gcttagaacg tcatacagct cgtttttaac
    17401 ctgatcccta atcagggggt ataacagagg cggccaaaaa atccggcctt gctcgtcaga
    17461 gtatctaccg cgcattatcc ccgaacggaa acccgaccat cacaacactt gcacagcttg
    17521 cagcagtagc cgggttacag ttcactctca gtaagcccaa ccactaacct ttcagacaag
    17581 cccctcatac cggggggatt atttcttacg ccagcaaaat ttcacgaccg gcgaggatgg
    17641 ccaagtgttt tttgctggca attttcgtgc agcagctggc gcccggattc attttttgct
    17701 gtcaggcatc aatcggtttc agcaacccgc cccgtaattc gctgctaacg catctcataa
    17761 cgcgcagata cagcgccccg cgccagtgtt tcacactgac ccggcgtacc gttcgcaagc
    17821 tcacgcgcta actgcgacag gctaaacatc gtctgatagt cagaaattgg cctggcaggg
    17881 gtgagggggg ttatcgctct cattcgggct tgttggttcg ccagtcctgg cgaacgtctc
    17941 cggcgcgatg ttacgacagc gcattatgta actacagttc gcgcctcttt cggaaatccc
    18001 ttcatgcgcg gtaaagcaat atacatcttt atgtaatctt tacaatgtaa agcattaaaa
    18061 atgattccat aaccatcatt tgatggtata atgaatttgt tggttgggaa tggttccctg
    18121 ccagattcca gaagcccaca cgggcgggag cgaaaaatga atattcagga agcattaaac
    18181 gtttttggtt tatccggtga tctgactgaa aaggacatca aggcggcata caaaaaagcg
    18241 gctttaaaat atcatccaga ccgcaatcca ttgggtgccg agctgatgaa agcagtaaat
    18301 gctgcgtttg attttctcat ggctaacatt gataaaatca atcagtttca aagcactgat
    18361 gaaaacgcac gttacaacta cggtgaagat ctggaaaaag ttctgaatac gctttccggc
    18421 cttacaggga ttgtctatga agttattggt aattgggtct ggattagcgg agaaactaaa
    18481 gaacacaaag acattttaaa ggaaatgggc tgtaagtggg catctaagaa aaaacaatgg
    18541 ttttaccgtc ctgaagaaca caaaagccgc tggaaccgta aagaacacag cattgaagaa
    18601 attcgtgaaa tgtatggtac agcgggtaaa cgtaaggcgt caggctggac acgtgtagaa
    18661 gcaagcgcat aaccggaatg ggggcgaaag ccccctagaa catggcaaag attgattcgg
    18721 agacacgttg atgaaaaaca agaccataac ggaagcggag ctgataaaca tttttgaaag
    18781 ttacggagcc tacatttgcc cggatgagat cgaagttaca gccaaagaat gcaatgaaaa
    18841 tggttcagtc ttgcaccgtg gcttaaacgc agaaggatgg gcgcatcttt ttgcgaagga
    18901 agaagcatat cagcaggaat gcgaagccca ggaagctgca agtgatgatg gacactttga
    18961 tgaatagtct taaaactgcc gtaattcgat ttacggcttt tttattgagt tcaaaaggct
    19021 gaatcgatga aagaacagaa aaatttcttt gaacggtata aaccggtgtt tgaaatcgtt
    19081 tgtcgaatcc tggggaacgg ctggcgtgta aatctgctcg atgattgcca gtacaggatt
    19141 aagctaacct cacctgattt taaaaattac tctatacata ttcgaatgga gaaaggaagg
    19201 ttagttatca ttggaagcgt agatagtcgc agctggagaa gtccttacca tacttgcaca
    19261 gtatcgccag agcgtaaccc tgtagaaatc gccgccgata ttgaaaagaa aatcctgtcg
    19321 gatgctttag ataatgtaga tatggcgcga gagtatgaac aacagttaca gcaaaaacgc
    19381 gagaaaaaac tgatcctgaa aggaatgcta tctcgtttag tgcatcttga aagctggcat
    19441 gggacattga ccgggtttaa agttgagaat gggttagatg gtaacgtatc agaacggggc
    19501 gacggatatg aaatggtaat tcgtggcctg agtgtagatc agctcataaa ggtagcgggg
    19561 tttattaaac agctatgagg caaaaaatga atgaagtcct gagcgacagg aaaaacaaag
    19621 gtaatgtaac atacaggatt gttgtgtctg aagatgcaac acgtttgttt attgaacttg
    19681 aaaaactgat gaaggtacgc tctaaagaag cggataaaaa aacaactaaa aagattgttt
    19741 tccaaaaatc attttattac gaagaattct cgaacgttaa agatgaaatt gatgatccaa
    19801 ttttattgaa attctataca gatactattg tgaaggtaca aaatcatgag ttttaagcca
    19861 acacctgaag aggtgaaaca agcacgtatt aaagctggct ttacgcagca ggaagccgct
    19921 gaacggtttg gttttacgtt atcagcctgg caagccaaag aaacatccgg taaaacgtct
    19981 cgtggtttag ccgctggtac gtatgaatta cttttgctcc tggctgatga acatccagat
    20041 taccagctcg ttaagagaga aaaaaatcag gataaagtga ctaaataaat tgcattacca
    20101 tcatatgatg gtataattta tttgtaggtc gggaatagtt ccttaccatg atccagtagc
    20161 ccaaacgggc gggagactaa aatgaacacg tatgttatca ctttccaggc tttaaacact
    20221 aagaaagaaa aaatcacctg ctctgctttt gtccattcag aaactctctt ccttgccgtt
    20281 cattctttcg aagataaaaa tcgcggtcgt ggttatgtta tcacgtctgt tagtgaattg
    20341 ttgtccgagg aactgacggc gaaaaattcc ctcaagaaaa atattaactt ttggtttaat
    20401 gagtgtggtt taagtaaatc tgaggttata aacgaagtaa ttaactggaa gaatttcgca
    20461 tataccctta aagaactgga ggaagccaaa aatgaagcga taagagaact gcggagttaa
    20521 tcaattaggg gtggtatcag gttgtggagg caacctgata ccgtgacact caattccctc
    20581 gcgaggaata taaaatgtcg gaacgcatgt tatcagcaat acagactgtt gaaaagggtg
    20641 ggcgtccggt ttttcccttg atgccattct ctgcttttcc tgagtacatg gcattactca
    20701 gaaaagccct ggaaaagaaa gaaacaaaag cactgataga aaaacaggag gtgctatgaa
    20761 aaaacaggag tttttagatt ttatcagtgc agaacagagg cggggagctg tccggttttc
    20821 gctgggattt aacagcaaag gggaaattgt attgcactgg actaacgagg ccgggttaag
    20881 agtctggagt atactaagcg gtaacagggg aaaaagtccc agccgggcaa accgggaaag
    20941 aatgagtaac ctccgccgct ggctccatga tgcccggcag ggcatggaag gcgacacacc
    21001 agaggcagaa taaaattccc gttcctgaat cgccgaagcc ctcccgttta cgggaggtgc
    21061 tttttttgta tattccgtaa aacagcgctc gcgccccctg ccaggccatt cgcgtagcga
    21121 atttatttcc gcccaagtta gccgcgaatc cgttgtctcc ggtcgcagac gcaccagatc
    21181 acagccacga tagcctttca ttttttgcat ttcgatggac gctgaagcac aatttatgtg
    21241 tggaggtagt tcactgcgat gccggaagga cgttcacttt tcagcaatga acggaccagc
    21301 actgaaacct gtactttgcc cagcttcagg gagccagcgg tccggatcat ttcgtcccac
    21361 tgaggggttc tagggatttt ccgtccaaaa acgacaaagt gctctggagg ccccgccgtc
    21421 tgtggcctcc agaggggtat tacttttttc gagatcccta tttgggctct gtttgagtaa
    21481 gatttagtct ttttgggcta aatccatggc attcgaagaa cgtgtccaaa tcttgtccga
    21541 ggcagaacaa gatgagttat atggaccccc cgctttcacc tccgccgacc aacgcttctt
    21601 tttctcgctg aacgataagg aactggcgat cgctaaaagc ctccgtcatc ggggccagcg
    21661 ttacatgctg gtggtactgc tgggctattt caaagccaag ccggtggtgc tgaatcccgg
    21721 ctttcatcag atcaagcagg acctcaaata cgtttatcaa accgttctac caggcccagg
    21781 ctgtagaccc tttaatctca cgccaaaaga gaacgaacgg atttaccaac gtgttttcca
    21841 gctctgcaac taccagcgct ggaatgtcaa agaccatgga gcggcgttga gagattactt
    21901 atcccagcaa gccagagcct ggacagcgcc taggcacctc ttcgatgcgg ccaatgaata
    21961 ttgttcgggg cagaagatcg caatccctgc ctacagcacg ctgcaaaaga tcatcagtca
    22021 ggtggtggga gacgaacagg aacacatggc cgcgcacctt gagcgtgcaa tgtcacgcgg
    22081 tcttaagcaa gcactggcgg agctcgtgaa cggcacaggt ccactgccgt tccgacagtt
    22141 gcgacaatcg gctcgtaact tcaccggaac cgagttggag aaagaactga ttgtctatcg
    22201 ccatatccag cattggatgc cggaagtgga tctgctgttg agcacgctat cactgtcgca
    22261 gaaaaatctg caacacctgg cagagaaagt cgactactac ggtgccaaac tgaaacgtca
    22321 aaccgtaggc agccaatggc tgtatttatt gtgctatctt caaacgcgat ggcagcaagc
    22381 gctggaacgt attgccgatg gctttgtgca tcatgtcaga cagaccaaac agaaggcaaa
    22441 ggattatgcg caggaagcgg tgtttaagga ttggcaaaaa gcagctaaaa atgtcagcaa
    22501 ggcagctgaa gtactgcacc tgttcattga tgacagcatt gatctgcaac taccgtttgc
    22561 aacagtaaga cagcaagcac tgagcctgct gaccaaaagg gatctggaat ctgtatgtct
    22621 cttcctgaac gagcagcgac gatcggtcga tgaagccatg tggcagtact gcgacgagaa
    22681 agaaagtctg cggaaaggtt tgctgcgaga gttgttccta tgtctgcgct tcgaaggctg
    22741 cgacggcacc cagcacttag cggccgcctt ggcgaaaaca caaaacgaac tcaacggcca
    22801 ggacgctcag ttgcaaactg ccgacaccag actcctttcc aaaaaatcac gtgaattcct
    22861 gctggatggt gaagggaata tcctgatcga tcgttatgag tggttcctct atcaacagat
    22921 tcctgatcgc ctgaatggcc agctgacgct gcctgatatc actaaatacc gggcactcga
    22981 cgccgacctg atcgacgggg aacattggcg aaaaaacaaa tatacgctgc ttcaacagag
    23041 ccattttaca aaattagcgg aggagcctga aaagctgatc aaacagatgg ccatggaatt
    23101 ggatacccgt ttgtacgaag tcggcgaata tcttgaacag gaagacaacc ggaatatcat
    23161 cttgcgtaat ccgcagggta aacgcttctg gcgcctgcct tcggccagca aacatcatct
    23221 ggtcaacaat cccttcttcc agcaaattcc cacaacgggg attgcggatg tactgcgcat
    23281 ggttgatcgt gacaccggtt tcattgactg cttcgctcat gtgctgggtt cccaatccag
    23341 aagccgttcc catgaatatg acctgttggc aattctggtc ggcaatgcaa ccaatcaagg
    23401 catttacggc atggcacaga tctctgatcg tacctatgat cagctcagca ctatccaggc
    23461 gaactatctt cgcctggaaa cattgaatgc tgctaacgac aacatcaata acgcgacagc
    23521 caagctaccc atcttccggt actacaacat ccaggaagat gtgatccacg ccagtgccga
    23581 tggtcaaaag ttcgaagccc ggcgcgagac cttcaaaacc cgttattcgt cgaagtactt
    23641 tggcactcaa aaaggtgttt ctgccatgac cttgatcgcc aatcacgctg cgatcaacgc
    23701 cagagtgatc ggcgccaacg aacatgaatc gcactacatc tttgatttgt tgatgagcaa
    23761 tacgtcagac atcattccgg atgtgctctc aaccgatacc catggggtga accatgtgaa
    23821 cttcgcgtta ctggatctgt tcggatacca gtttgcccca cgctatgccc aggttggcaa
    23881 agtgatcaat gacatgtttg atgtcaagga agacaaagaa caccgaattc agctgtgctt
    23941 aaaaaagcca atcaataccc atcgtattgc gcagcactgg gataccatcc aacggattgc
    24001 agtatcactt aagcagcgga aaacaacgca agccaccttg gtgagaaagc tctcggagta
    24061 caagcgcaat cacccgctgc tggaagccct gacggaatac aatcgcctgg tgaaagcgaa
    24121 ttatctactg tgctacatcg atgatgccag tttaagaaac tatgttcagc gcgcgctgaa
    24181 ccggggagag gcctatcacc aactgcgtcg ggccgtgagc agcgtcaatg gggatcagtt
    24241 ccggggcagt tcagacgaag aaatccagct atggaatgag tgcgctcgcc tggtcaccaa
    24301 tgccatcgtt tacttcaact ccaggatact cagccagctg ttgaccagct tcgaatacca
    24361 aggagatacc aagagaatag atatcgtcaa acaggcatcc cctgtggcct ggcacaacat
    24421 taacctcaag gggacttacc acttcgaatt gagcgaaaaa ttgccagatc tggaggagct
    24481 tatgcgctca atcgagggat atttacccgt cagcgaaaag taatacccct ctggaggcca
    24541 cggacggcgc ggcctccaga gcactttgtc gtttttggac ggaaaatccc tagaacccca
    24601 ttatctaaaa atacttaatt gtcttttaac gtcgctaaat tttaaataaa taagtgaaga
    24661 gtgttaggga aggtgcgaat aagcggggaa attcttctcg gctgactcag tcatttcatt
    24721 tcttcatgtt tgagccgatt ttttctcccg taaatgcctt gaatcagcct atttagaccg
    24781 tttcttcgcc atttaaggcg ttatccccag tttttagtga gatctctccc actgacgtat
    24841 catttggtcc gcccgaaaca ggttggccag cgtgaataac atcgccagtt ggttatcgtt
    24901 tttcagcaac cccttgtatc tggctttcac gaagccgaac tgtc
//
