LOCUS       NZ_CP060917            24665 bp    DNA     circular CON 24-MAY-2024
DEFINITION  Escherichia coli strain EC18 plasmid pEC18-NDM-5, complete sequence.
ACCESSION   NZ_CP060917
VERSION     NZ_CP060917.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15904660
            Assembly: GCF_022558825.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24665)
  AUTHORS   Ruan,Z.
  TITLE     Complete genome sequence of carbapenem resistant Escherichia coli
            isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24665)
  AUTHORS   Ruan,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-AUG-2020) Department of Clinical laboratory, Sir Run
            Run Shaw Hospital, School of Medicine, Zhejiang University, 3
            Qingchun East Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022558825.1-RS_2024_05_24
            Annotation Date                   :: 05/24/2024 04:22:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,177
            CDSs (total)                      :: 5,051
            Genes (coding)                    :: 4,789
            CDSs (with protein)               :: 4,789
            Genes (RNA)                       :: 126
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 94
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 262
            CDSs (without protein)            :: 262
            Pseudo Genes (ambiguous residues) :: 0 of 262
            Pseudo Genes (frameshifted)       :: 74 of 262
            Pseudo Genes (incomplete)         :: 190 of 262
            Pseudo Genes (internal stop)      :: 44 of 262
            Pseudo Genes (multiple problems)  :: 42 of 262
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP060917.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24665
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="EC18"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pEC18-NDM-5"
                     /geo_loc_name="China: Hangzhou"
                     /collection_date="2016-12-20"
                     /collected_by="Long Sun"
     gene            complement(24..884)
                     /locus_tag="H9203_RS25580"
                     /old_locus_tag="H9203_25315"
     CDS             complement(24..884)
                     /locus_tag="H9203_RS25580"
                     /old_locus_tag="H9203_25315"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     gene            complement(1067..1624)
                     /locus_tag="H9203_RS25585"
                     /old_locus_tag="H9203_25320"
     CDS             complement(1067..1624)
                     /locus_tag="H9203_RS25585"
                     /old_locus_tag="H9203_25320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001235713.1"
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            1788..>2387
                     /locus_tag="H9203_RS25590"
                     /old_locus_tag="H9203_25325"
                     /pseudo=""
     CDS             1788..>2387
                     /locus_tag="H9203_RS25590"
                     /old_locus_tag="H9203_25325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /name="DUF4158 domain-containing protein"
     gene            complement(2444..3148)
                     /locus_tag="H9203_RS25595"
                     /old_locus_tag="H9203_25330"
     CDS             complement(2444..3148)
                     /locus_tag="H9203_RS25595"
                     /old_locus_tag="H9203_25330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <3216..>4481
                     /locus_tag="H9203_RS25600"
                     /old_locus_tag="H9203_25335"
                     /pseudo=""
     CDS             <3216..>4481
                     /locus_tag="H9203_RS25600"
                     /old_locus_tag="H9203_25335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /name="Tn3-like element Tn3 family transposase"
     gene            complement(4539..5597)
                     /locus_tag="H9203_RS25605"
                     /old_locus_tag="H9203_25340"
     CDS             complement(4539..5597)
                     /locus_tag="H9203_RS25605"
                     /old_locus_tag="H9203_25340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343765.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="WP_241408387.1"
                     /translation="MDEKSLYAHILNLSDPWQVKSLSLDENAGSVTVTIEIAENTRLAC
                     PTCGKSCSVHDHRHRKWRHLDTCQFTTIVEADVPRIMCPEHGCLTLPVPWAGPGSRYTL
                     LFESFVLSWLKISTVDAVRKQLKLSWNAVDGIMTRAVKRGLARIKKPLSARHMNVDEVA
                     FKKGHRYITVISDRDGRALALTDDRGTESLAGYLRTLTDGQLLAIKTLSMDMNAGYIRA
                     ARIHLPSAVEKIAFDRFHVAKQLGEVVDKTRQNEHPHLPVESRHQAKGTRFLWQYSDKW
                     MTESRQEKLMWLRAQMKLTSQCWALKELAKDIWNRPWSEERRSDWQRWLALAANSDVPM
                     MKNAAKTIGKGV"
                     /name="ISL3 family transposase"
     gene            5699..5938
                     /locus_tag="H9203_RS25610"
                     /old_locus_tag="H9203_25345"
     CDS             5699..5938
                     /locus_tag="H9203_RS25610"
                     /old_locus_tag="H9203_25345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001549892.1"
                     /translation="MPRHYEIDSAWRASIKREPNGRQTVTTEAFVSQLALINFHWSCRQ
                     ANQWIETYVTVFKDISTQEGENRTFMLFNPNGGR"
                     /name="hypothetical protein"
     gene            5941..6297
                     /locus_tag="H9203_RS25615"
     CDS             5941..6297
                     /locus_tag="H9203_RS25615"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="WP_004199403.1"
                     /translation="MGFPSPATDYQENRLSLDQHCNTGAPGVFFFRSDTYSFREGIKPG
                     ALLIVDFGGTPVDGSLVLCVLEQEFRIMRLRLHPKRCLQELDKLDNFRAIPDDDEDGLE
                     VRGVITHIVALLQS"
                     /name="S24 family peptidase"
     gene            complement(6331..7035)
                     /locus_tag="H9203_RS25620"
                     /old_locus_tag="H9203_25350"
     CDS             complement(6331..7035)
                     /locus_tag="H9203_RS25620"
                     /old_locus_tag="H9203_25350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067834.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YISSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <7100..7228
                     /gene="cutA"
                     /locus_tag="H9203_RS25625"
                     /old_locus_tag="H9203_25355"
                     /pseudo=""
     CDS             <7100..7228
                     /gene="cutA"
                     /locus_tag="H9203_RS25625"
                     /old_locus_tag="H9203_25355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201171.1"
                     /GO_process="GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /name="cutA"
     gene            7233..>7607
                     /locus_tag="H9203_RS25630"
                     /pseudo=""
     CDS             7233..>7607
                     /locus_tag="H9203_RS25630"
                     /inference="COORDINATES: protein motif:HMM:NF022853.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD
                     domain-containing protein"
                     /name="protein-disulfide reductase DsbD domain-containing
                     protein"
     gene            <7707..8264
                     /locus_tag="H9203_RS25635"
                     /pseudo=""
     CDS             <7707..8264
                     /locus_tag="H9203_RS25635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006399920.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocation (TAT) pathway signal
                     sequence domain protein"
                     /name="twin-arginine translocation (TAT) pathway signal
                     sequence domain protein"
     gene            complement(8275..8913)
                     /locus_tag="H9203_RS25640"
                     /old_locus_tag="H9203_25365"
     CDS             complement(8275..8913)
                     /locus_tag="H9203_RS25640"
                     /old_locus_tag="H9203_25365"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /GO_function="GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="WP_004201168.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVAG
                     ALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKPVW
                     KALPVASASDVARAAAYAGAADLILFDAKTPKGALPGGMGLAFDWSLLAGYRGALPWGL
                     AGGLNPTNVAEAIARTGAPLVDTSSGVESAPGVKDTDKITNFAFAVRLA"
                     /name="phosphoribosylanthranilate isomerase"
     gene            complement(8918..9283)
                     /gene="ble"
                     /locus_tag="H9203_RS25645"
                     /old_locus_tag="H9203_25370"
     ARG             complement(8922..9283)
                     /name="ble"
                     /gene="ble"
                     /gene_name="bleomycin binding protein Ble-MBL"
                     /tool="amrfinderplus"
                     /drug_class="BLEOMYCIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9287..10099)
                     /locus_tag="H9203_RS25650"
                     /old_locus_tag="H9203_25375"
     CDS             complement(9287..10099)
                     /locus_tag="H9203_RS25650"
                     /old_locus_tag="H9203_25375"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="WP_023408309.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQR
                     FGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQILNW
                     IKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHSLTF
                     AANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLG
                     DADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
                     /name="subclass B1 metallo-beta-lactamase NDM-5"
     gene            10334..11314
                     /locus_tag="H9203_RS25655"
                     /old_locus_tag="H9203_25380"
     CDS             10334..11314
                     /locus_tag="H9203_RS25655"
                     /old_locus_tag="H9203_25380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416498.2"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS5 family transposase"
                     /protein_id="WP_000019402.1"
                     /translation="MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFY
                     PKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTT
                     IMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPE
                     MHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAG
                     YQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRAKVEHPFRI
                     IKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH"
                     /name="IS5-like element IS5 family transposase"
     gene            complement(11605..14622)
                     /locus_tag="H9203_RS25660"
                     /old_locus_tag="H9203_25385"
     CDS             complement(11605..14622)
                     /locus_tag="H9203_RS25660"
                     /old_locus_tag="H9203_25385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490160.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element IS3000 family transposase"
                     /protein_id="WP_004199413.1"
                     /translation="MAFEERVQILSEAEQDELYGPPAFTSADQRFFFSLNDKELAIAKS
                     LRHRGQRYMLVVLLGYFKAKPVVLNPGFHQIKQDLKYVYQTVLPGPGCRPFNLTPKENE
                     RIYQRVFQLCNYQRWNVKDHGAALRDYLSQQARAWTAPRHLFDAANEYCSGQKIAIPAY
                     STLQKIISQVVGDEQEHMAAHLERAMSRGLKQALAELVNGTGPLPFRQLRQSARNFTGT
                     ELEKELIVYRHIQHWMPEVDLLLSTLSLSQKNLQHLAEKVDYYGAKLKRQTVGSQWLYL
                     LCYLQTRWQQALERIADGFVHHVRQTKQKAKDYAQEAVFKDWQKAAKNVSKAAEVLHLF
                     IDDSIDLQLPFATVRQQALSLLTKRDLESVCLFLNEQRRSVDEAMWQYCDEKESLRKGL
                     LRELFLCLRFEGCDGTQHLAAALAKTQNELNGQDAQLQTADTRLLSKKSREFLLDGEGN
                     ILIDRYEWFLYQQIPDRLNGQLTLPDITKYRALDADLIDGEHWRKNKYTLLQQSHFTKL
                     AEEPEKLIKQMAMELDTRLYEVGEYLEQEDNRNIILRNPQGKRFWRLPSASKHHLVNNP
                     FFQQIPTTGIADVLRMVDRDTGFIDCFAHVLGSQSRSRSHEYDLLAILVGNATNQGIYG
                     MAQISDRTYDQLSTIQANYLRLETLNAANDNINNATAKLPIFRYYNIQEDVIHASADGQ
                     KFEARRETFKTRYSSKYFGTQKGVSAMTLIANHAAINARVIGANEHESHYIFDLLMSNT
                     SDIIPDVLSTDTHGVNHVNFALLDLFGYQFAPRYAQVGKVINDMFDVKEDKEHRIQLCL
                     KKPINTHRIAQHWDTIQRIAVSLKQRKTTQATLVRKLSEYKRNHPLLEALTEYNRLVKA
                     NYLLCYIDDASLRNYVQRALNRGEAYHQLRRAVSSVNGDQFRGSSDEEIQLWNECARLV
                     TNAIVYFNSRILSQLLTSFEYQGDTKRIDIVKQASPVAWHNINLKGTYHFELSEKLPDL
                     EELMRSIEGYLPVSEK"
                     /name="Tn3-like element IS3000 family transposase"
     gene            complement(15115..15372)
                     /locus_tag="H9203_RS25665"
                     /old_locus_tag="H9203_25395"
     CDS             complement(15115..15372)
                     /locus_tag="H9203_RS25665"
                     /old_locus_tag="H9203_25395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004199355.1"
                     /translation="MKKQEFLDFISAEQRRGAVRFSLGFNSKGEIVLHWTNEAGLRVWS
                     ILSGNRGKSPSRANRERMSNLRRWLHDARQGMEGDTPEAE"
                     /name="hypothetical protein"
     gene            complement(15369..15533)
                     /locus_tag="H9203_RS25670"
                     /old_locus_tag="H9203_25400"
     CDS             complement(15369..15533)
                     /locus_tag="H9203_RS25670"
                     /old_locus_tag="H9203_25400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000004083.1"
                     /translation="MSERMLSAIQTVEKGGRPVFPLMPFSAFPEYMALLRKALEKKETK
                     ALIEKQEVL"
                     /name="hypothetical protein"
     gene            complement(15608..15946)
                     /locus_tag="H9203_RS25675"
                     /old_locus_tag="H9203_25405"
     CDS             complement(15608..15946)
                     /locus_tag="H9203_RS25675"
                     /old_locus_tag="H9203_25405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001099725.1"
                     /translation="MNTYVITFQALNTKKEKITCSAFVHSETLFLAVHSFEDKNRGRGY
                     VITSVSELLSEELTAKNSLKKNINFWFNECGLSKSEVINEVINWKNFAYTLKELEEAKN
                     EAIRELRS"
                     /name="hypothetical protein"
     gene            complement(16040..16282)
                     /locus_tag="H9203_RS25680"
                     /old_locus_tag="H9203_25410"
     CDS             complement(16040..16282)
                     /locus_tag="H9203_RS25680"
                     /old_locus_tag="H9203_25410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000008707.1"
                     /translation="MSFKPTPEEVKQARIKAGFTQQEAAERFGFTLSAWQAKETSGKTS
                     RGLAAGTYELLLLLADEHPDYQLVKREKNQDKVTK"
                     /name="hypothetical protein"
     gene            complement(16272..16541)
                     /locus_tag="H9203_RS25685"
                     /old_locus_tag="H9203_25415"
     CDS             complement(16272..16541)
                     /locus_tag="H9203_RS25685"
                     /old_locus_tag="H9203_25415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001006717.1"
                     /translation="MNEVLSDRKNKGNVTYRIVVSEDATRLFIELEKLMKVRSKEADKK
                     TTKKIVFQKSFYYEEFSNVKDEIDDPILLKFYTDTIVKVQNHEF"
                     /name="hypothetical protein"
     gene            complement(16550..17101)
                     /locus_tag="H9203_RS25690"
                     /old_locus_tag="H9203_25420"
     CDS             complement(16550..17101)
                     /locus_tag="H9203_RS25690"
                     /old_locus_tag="H9203_25420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000662998.1"
                     /translation="MKEQKNFFERYKPVFEIVCRILGNGWRVNLLDDCQYRIKLTSPDF
                     KNYSIHIRMEKGRLVIIGSVDSRSWRSPYHTCTVSPERNPVEIAADIEKKILSDALDNV
                     DMAREYEQQLQQKREKKLILKGMLSRLVHLESWHGTLTGFKVENGLDGNVSERGDGYEM
                     VIRGLSVDQLIKVAGFIKQL"
                     /name="hypothetical protein"
     gene            complement(17161..17397)
                     /locus_tag="H9203_RS25695"
                     /old_locus_tag="H9203_25425"
     CDS             complement(17161..17397)
                     /locus_tag="H9203_RS25695"
                     /old_locus_tag="H9203_25425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000792381.1"
                     /translation="MKNKTITEAELINIFESYGAYICPDEIEVTAKECNENGSVLHRGL
                     NAEGWAHLFAKEEAYQQECEAQEAASDDGHFDE"
                     /name="hypothetical protein"
     gene            complement(17456..17971)
                     /locus_tag="H9203_RS25700"
                     /old_locus_tag="H9203_25430"
     CDS             complement(17456..17971)
                     /locus_tag="H9203_RS25700"
                     /old_locus_tag="H9203_25430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="WP_001025390.1"
                     /translation="MNIQEALNVFGLSGDLTEKDIKAAYKKAALKYHPDRNPLGAELMK
                     AVNAAFDFLMANIDKINQFQSTDENARYNYGEDLEKVLNTLSGLTGIVYEVIGNWVWIS
                     GETKEHKDILKEMGCKWASKKKQWFYRPEEHKSRWNRKEHSIEEIREMYGTAGKRKASG
                     WTRVEASA"
                     /name="DnaJ domain-containing protein"
     gene            18225..18383
                     /locus_tag="H9203_RS25705"
                     /old_locus_tag="H9203_25435"
     CDS             18225..18383
                     /locus_tag="H9203_RS25705"
                     /old_locus_tag="H9203_25435"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_152913118.1"
                     /translation="MRAITPLTPARPISDYQTMFSLSQLARELANGTPGQCETLARGAV
                     SARYEMR"
                     /name="hypothetical protein"
     gene            complement(18561..>18713)
                     /locus_tag="H9203_RS25710"
                     /old_locus_tag="H9203_25440"
                     /pseudo=""
     CDS             complement(18561..>18713)
                     /locus_tag="H9203_RS25710"
                     /old_locus_tag="H9203_25440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /name="DNA-binding protein"
     gene            19324..20337
                     /locus_tag="H9203_RS25715"
                     /old_locus_tag="H9203_25445"
     CDS             19324..20337
                     /locus_tag="H9203_RS25715"
                     /old_locus_tag="H9203_25445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348704.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001348704.1"
                     /translation="MRLLLSLDMKILRSSYLKVRGFLIKGCIVVLNYNLCGVMICLHRK
                     GYMRLIVKTVTGLTKVRHRNEVGVTLASLSLSAKRVLFLALCQIDTKEMLDDDILEVDA
                     DFFSKATSLDKYASYAALKEGAKVLSSTTLVLNRDDLKNLADELGILSSKNKIPDRLDL
                     NLTEFCAYYDHLATVRIKFTNTAKRYFSKLIGSENRYTTQVLKSVVLLNSVNSTNLYQV
                     IRKYYSQNSSKKSFDISVDDLKEEMGLYTIEEGEKKYKYPKYSFFVRDVINKSINEIIE
                     KTEINQLSFSVVGKKGRMAHMLRFEFSINEKSSSFSEDDMAFLEEFDKVVPPKKNK"
                     /name="replication initiation protein"
     gene            20346..20789
                     /locus_tag="H9203_RS25720"
                     /old_locus_tag="H9203_25450"
     CDS             20346..20789
                     /locus_tag="H9203_RS25720"
                     /old_locus_tag="H9203_25450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001074369.1"
                     /translation="MAKIYEFPQGAERSKLKKEIIRERKKRLRETNGNPVIRHAKWFWF
                     YLRLATAGALHLVSVISLAVLGAFSKAIFWIGGMLCVVTWFHLERQFWTPQNFTIPVIV
                     TLWGLSLFATPLMELLNKKMPWYRLLVPDAKHTSTEATNDDQP"
                     /name="hypothetical protein"
     gene            20977..21330
                     /gene="ddp1"
                     /locus_tag="H9203_RS25725"
                     /old_locus_tag="H9203_25455"
     CDS             20977..21330
                     /gene="ddp1"
                     /locus_tag="H9203_RS25725"
                     /old_locus_tag="H9203_25455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_000877224.1"
                     /translation="MKYQVKEFINEKYSKAVNILKDNLKEHYHIFYGLRLSEILFPASE
                     YGSEMFFQEFEAINSVILPLVIFDLIDRKPIMVIGFGEVCGVDSLVDSGIEVVSLDGLS
                     DLLLVEKLTPLFN"
                     /name="ddp1"
     gene            complement(21351..21635)
                     /locus_tag="H9203_RS25730"
                     /old_locus_tag="H9203_25460"
     CDS             complement(21351..21635)
                     /locus_tag="H9203_RS25730"
                     /old_locus_tag="H9203_25460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001043731.1"
                     /translation="MNKSWLEQQVQNEKLKKVQEEKKDGTIQKGLYRVRIKDKYRWDLW
                     ENDFRVVIAYSKDDAELKFTEMTGFNEHYYIESIEKIVLSDIEKILLEN"
                     /name="hypothetical protein"
     gene            complement(21671..21982)
                     /locus_tag="H9203_RS25735"
                     /old_locus_tag="H9203_25465"
     CDS             complement(21671..21982)
                     /locus_tag="H9203_RS25735"
                     /old_locus_tag="H9203_25465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000469598.1"
                     /translation="MFIFRYIKTLINIYLLYIQPILGMFLIGIGLWGFYAPDEGTCTNL
                     NIELCAVSAIDVLKPAIFVFLGIITVAGWYFTELQPKLRGEGKYMKVKTGVKPEDFVK"
                     /name="hypothetical protein"
     gene            complement(22188..22472)
                     /locus_tag="H9203_RS25740"
                     /old_locus_tag="H9203_25470"
     CDS             complement(22188..22472)
                     /locus_tag="H9203_RS25740"
                     /old_locus_tag="H9203_25470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001185481.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVAGKPKLMNFRL
                     PAYFEEILEAEAQRTGQSKTTVLKAALAAFDNLDENLKNHWLLESAKLG"
                     /name="hypothetical protein"
     gene            complement(22572..23234)
                     /locus_tag="H9203_RS25745"
                     /old_locus_tag="H9203_25475"
     CDS             complement(22572..23234)
                     /locus_tag="H9203_RS25745"
                     /old_locus_tag="H9203_25475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516402.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHDL
                     LSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVSDI
                     VVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDLDKL
                     LRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIGIL"
                     /name="division plane positioning ATPase MipZ"
     gene            23615..24277
                     /locus_tag="H9203_RS25750"
                     /old_locus_tag="H9203_25480"
     CDS             23615..24277
                     /locus_tag="H9203_RS25750"
                     /old_locus_tag="H9203_25480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549893.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001549893.1"
                     /translation="MTQTVPKGFVRAYLRASTTEQDATRALDTINTFAIERGLSICNYY
                     IENESGSKLERPELFRLLKDCQQNDILLVEDVDRLSRLVGEDWNTLKKMIRQKDIRVVA
                     VNVPTTWLASGHNDFDSRMFSAINDMLLDMLAAVARRDYEQRRERQQQGIARAKREGKY
                     KGRQVNQSRYDAINRLIASGSSWSQIQKVLGCSRATISKAVKQQTVNKMNHEPEGRE"
                     /name="recombinase family protein"
     gene            complement(24366..>24539)
                     /locus_tag="H9203_RS25755"
                     /old_locus_tag="H9203_25485"
                     /pseudo=""
     CDS             complement(24366..>24539)
                     /locus_tag="H9203_RS25755"
                     /old_locus_tag="H9203_25485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343760.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     ARG             complement(28..884)
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(9291..10099)
                     /name="blaNDM-5"
                     /gene="blaNDM-5"
                     /gene_name="subclass B1 metallo-beta-lactamase NDM-5"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(8919..9178)
                     /name="BRP(MBL)"
                     /gene="BRP(MBL)"
                     /gene_name="Bleomycin resistant protein"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="71.07"
     Typing          19466..20337
                     /name="IncX3"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tatgagtaaa cttggtctga cagttaccaa tgcttaatca gtgaggcacc tatctcagcg
       61 atctgtctat ttcgttcatc catagttgcc tgactccccg tcgtgtagat aactacgata
      121 cgggagggct taccatctgg ccccagtgct gcaatgatac cgcgagaccc acgctcaccg
      181 gctccagatt tatcagcaat aaaccagcca gccggaaggg ccgagcgcag aagtggtcct
      241 gcaactttat ccgcctccat ccagtctatt aattgttgcc gggaagctag agtaagtagt
      301 tcgccagtta atagtttgcg caacgttgtt gccattgctg caggcatcgt ggtgtcacgc
      361 tcgtcgtttg gtatggcttc attcagctcc ggttcccaac gatcaaggcg agttacatga
      421 tcccccatgt tgtgcaaaaa agcggttagc tccttcggtc ctccgatcgt tgtcagaagt
      481 aagttggcag cagtgttatc actcatggtt atggcagcac tgcataattc tcttactgtc
      541 atgccatccg taagatgctt ttctgtgact ggtgagtact caaccaagtc attctgagaa
      601 tagtgtatgc ggcgaccgag ttgctcttgc ccggcgtcaa cacgggataa taccgcacca
      661 catagcagaa ctttaaaagt gctcatcatt ggaaaacgtt cttcggggcg aaaactctca
      721 aggatcttac cgctgttgag atccagttcg atgtaaccca ctcgtgcacc caactgatct
      781 tcagcatctt ttactttcac cagcgtttct gggtgagcaa aaacaggaag gcaaaatgcc
      841 gcaaaaaagg gaataagggc gacacgaaaa tgttgaatac tcatactctt cctttttcaa
      901 tattattgaa gcatttacca gggttattgt ctcatgagcg gatacatatt tgaatgtatt
      961 tagaaaaata aacaaatagg ggttccgcgc acatttcccc gaaaagtgcc acctgacgtc
     1021 taagaaacca ttattatcat gacattaacc tataaaaata ggcgtatcac gaggcccttt
     1081 cgtcttcaag aattttataa accgtggagc gggcaatact gagctgatga gcaatttccg
     1141 ttgcaccagt gcccttctga tgaagcgtca gcacgacgtt cctgtccacg gtacgcctgc
     1201 ggccaaattt gattcctttc agctttgctt cctgtcggcc ctcattcgtg cgttctagga
     1261 tcctccggcg ttcagcctgt gccacagccg acaggatggt gaccaccatt tgccccatat
     1321 caccgtcggt actgatcccg tcatcaatga accggactgc cacgccctga gcgtcaaatt
     1381 cctttatcag ttggatcata tcggcagtgt cgcggccaag acggtcgagc ttcttaacca
     1441 gaatgacatc accttcctcc accttcatcc tcagcaaatc cagcccttcc cggtctgttg
     1501 aactgccgga tgccttatcg gtaaatatac ggtttgcttt cacacctgcg tctttgagtg
     1561 ctctgacctg aagatcaaga gactgctgac tggttgagac ccgagcgtaa ccaaaaagtc
     1621 gcataaaaat gtaccttaaa tcgaatatcg gacaactcat gtctattatt acaaatttac
     1681 gatttaatag acatattaat gtaacagttt tacgatgtcc gataatttat aacatttcgt
     1741 acggttggaa aaatgttact aaatgcccgt caggcaggga ggccgatatg cccgttgact
     1801 ttctgaccac tgagcagact gaaagctatg gcagattcac cggtgaaccg gatgagcttc
     1861 agctggcacg atattttcac cttgatgaag cagacaagga atttatcgga aaaagcagag
     1921 gtgatcacaa ccgtctgggc attgccctgc aaattggatg tgtccgtttt ctgggcacct
     1981 tcctcaccga tatgaatcat attccttccg gcgtccggca ttttaccgcc agacagctcg
     2041 ggattcgtga tatcaccgtt cttgcagaat acggtcagag ggaaaatacc cgccgtgagc
     2101 atgcagcgct gatacgtcag cactatcagt atcgtgaatt tgcctggccc tggacatttc
     2161 gccttacccg tcttttatat acccggagct ggataagcaa cgaacgtcct ggcctgcttt
     2221 tcgatctggc gacagggtgg cttatgcaac atcgtattat tctccccgga gccactacgc
     2281 tgacccggtt gatttcagag gtaagggaaa aggcgacgtt gcgcctgtgg aacaaactgg
     2341 cactgatacc gtcagccgaa cagcgttcac agctggagat gctgctgggg cggcactgtt
     2401 gcaaagttag cgatgaggca gccttttgtc ttattcaaag gccttacatt tcaaaaactc
     2461 tgcttaccag gcgcatttcg cccaggggat caccataata aaatgctgag gcctggcctt
     2521 tgcgtagtgc acgcatcacc tcaatacctt tgatggtggc gtaagccgtc ttcatggatt
     2581 taaatcccag cgtggcgccg attatccgtt tcagtttgcc atgatcgcat tcaatcacgt
     2641 tgttccggta cttaatctgt cggtgttcaa cgtcagacgg gcaccggcct tcgcgtttga
     2701 gcagagcaag cgcgcgacca taggcgggcg ctttatccgt gttgatgaat cgcgggatct
     2761 gccacttctt cacgttgttg aggattttac ccagaaaccg gtatgcagct ttgctgttac
     2821 gacgggagga gagataaaaa tcgacagtgc ggccccggct gtcgacggcc cggtacagat
     2881 acgcccagcg gccattgacc ttcacgtagg tttcatccat gtgccacggg caaagatcgg
     2941 aagggttacg ccagtaccag cgcagccgtt tttccatttc aggcgcataa cgctgaaccc
     3001 agcggtaaat cgtggagtga tcgacattca ctccgcgttc agccagcatc tcctgcagct
     3061 cacggtaact gatgccgtat ttgcagtacc agcgtacggc ccacagaatg atgtcacgct
     3121 gaaaatgccg gcctttgaat gggttcatgt gcagctccat cagcaaaagg ggatgataag
     3181 tttatcacca ccgactattt gcaacagtgc cgaaacgact gagcaaaatg atcagtgatc
     3241 tactccctcc ggtggattta acggagttgc tgctcgaaat taacgcccat accggatttg
     3301 ctgatgagtt tttccatgct agtgaagcca gtgccagagt tgatgatctg cccgtcagca
     3361 tcagcgccgt gctgatggct gaagcctgca atatcggtct ggaaccactg atcagatcaa
     3421 atgttcctgc actgacccga caccggctga actggacaaa agcgaactat ctgcgggctg
     3481 aaactatcac cagcgctaat gccagactgg ttgattttca ggcaacgctg ccactggcac
     3541 agatatgggg tggaggagaa gtggcatctg cagatggaat gcgctttgtt acgccagtca
     3601 gaacaatcaa tgccggaccg aaccgcaaat actttggtaa taacagaggg atcacctggt
     3661 acaactttgt gtccgatcag tattccggct ttcatggcat cgttataccg gggacgctga
     3721 gggactctat ctttgtgctg gaaggtcttc tggaacagga gaccgggctg aatccaaccg
     3781 aaattatgac cgatacagca ggtgccagcg aacttgtctt tggccttttc tggctgctgg
     3841 gataccagtt ttctccacgc ctggctgatg ccggtgcttc ggttttctgg cgaatggacc
     3901 atgatgccga ctatggcgtg ctgaatgata ttgccagagg gcaatcagat ccccgaaaaa
     3961 tagtccttca gtgggacgaa atgatccgga ccgctggctc cctgaagctg ggcaaagtac
     4021 aggtttcagt gctggtccgt tcattgctga aaagtgaacg tccttccgga ctgactcagg
     4081 caatcattga agtggggcgc atcaacaaaa cgctgtatct gcttaattat attgatgatg
     4141 aagattaccg ccggcgcatt ctgacccagc ttaatcgggg agaaagtcgc catgccgttg
     4201 ccagagccat ctgtcacggt caaaaaggtg agataagaaa acgatatacc gacggtcagg
     4261 aagatcaact gggcacactg gggctggtca ctaacgccgt cgtgttatgg aacactattt
     4321 atatgcaggc agccctggat catctccggg cgcagggtga aacactgaat gatgaagata
     4381 tcgcacgcct ctccccgctt tgccacggac atatcaatat gctcggccat tattccttca
     4441 cgctggcaga actggtgacc aaaggacatc tgagaccatt aaaagaggcg tcagaggcag
     4501 aaaacgttgc ttaacgtgag ttttcgttcc actgagcgtc agaccccttt tcctatcgtt
     4561 ttcgcggcat ttttcatcat gggaacgtca ctgttagccg ccagcgccaa ccatctctgc
     4621 cagtcactcc gtctttcctc gctccatggc ctgttccaga tatcctttgc cagctctttc
     4681 agcgcccagc actggctcgt cagcttcatc tgtgcacgca gccacatcag cttttcctgc
     4741 cgggattcgg tcatccactt atcgctgtac tgccacagga agcgggttcc ttttgcctgg
     4801 tgtcggcttt caacagggag gtgcggatgt tcattctgac gggttttatc aactacctcg
     4861 cccagttgct tcgccacatg gaagcggtca aaggcgattt tctcaaccgc actgggtaag
     4921 tggatacgcg ctgctcttat atagcccgcg ttcatgtcca ttgagagcgt tttgatagcc
     4981 agcaactgcc catcagtgag cgtgcgaaga tagccggcaa gactctctgt gccgcgatca
     5041 tccgttaagg ccagcgcccg accatcgcga tcggagatca ccgttatgta acgatgtcct
     5101 tttttaaagg cgacctcatc cacattcata tgacgggcgg ataatggctt ttttatccgg
     5161 gcaagacctc gcttaactgc ccgggtcata atgccgtcaa ccgcattcca actgagctta
     5221 agttgcttcc tgacagcatc aacggtgctg attttcagcc atgagagaac gaacgattcg
     5281 aatagcaacg tataccggct tccggggcca gcccacggaa caggcaacgt caggcagcca
     5341 tgctccggac acataattcg tggaacatcg gcttcaacaa tagtggtgaa ctggcaggta
     5401 tcaagatggc gccatttacg atgacggtga tcgtgaacag aacaggattt accgcaggtc
     5461 ggacaggcta gccgggtgtt ttcagcgatc tcaatagtga cagtaacaga accggcattt
     5521 tcatcgagag aaagggactt tacctgccac ggatcggaca ggttgagaat atgagcgtag
     5581 agggactttt cgtccatggc ggtgacctct ggcgattaaa tacaccatta tcatgccttc
     5641 agccaccaca acaagggaag acccatatgc atacagctat attgatcgga ggtttttcat
     5701 gcctagacac tatgaaattg actcagcctg gcgtgcgagc attaagcgtg agccgaacgg
     5761 tcgtcagaca gttacgacag aagcctttgt cagccagctt gcgctgatta attttcactg
     5821 gagttgtcgc caagcaaatc agtggattga aacctacgtg accgttttta aagacatttc
     5881 cactcaggaa ggagagaacc ggacattcat gctttttaac cccaacggag gccgttaaaa
     5941 atgggttttc catcgccagc aaccgactac caggaaaaca ggctgtcact cgatcagcac
     6001 tgtaatacag gagcgccggg agtattcttt tttcgaagtg atacctactc tttccgggaa
     6061 gggataaagc ctggtgcgct gctcatagta gattttgggg gcacgcccgt tgacgggtct
     6121 ttggtgctct gtgtcctgga acaagaattc aggatcatgc gattgcgact acaccccaag
     6181 cggtgtctcc aggaactcga taagctggat aacttcaggg ctatacctga tgacgatgag
     6241 gacgggttgg aggtcagggg ggtcattacg cacattgtgg cactgttgca aagttagcga
     6301 tgaggcagcc ttttgtctta ttcaaaggcc ttacatttca aaaactctgc ttaccaggcg
     6361 catttcgccc aggggatcac cataataaaa tgctgaggcc tggcctttgc gtagtgcacg
     6421 catcacctca atacctttga tggtggcgta agccgtcttc atggatttaa atcccagcgt
     6481 ggcgccgatt atccgtttca gtttgccatg atcgcattca atcacgttgt tccggtactt
     6541 aatctgtcgg tgttcaacgt cagacgggca ccggccttcg cgtttgagca gagcaagcgc
     6601 gcgaccatag gcgggcgctt tatccgtgtt gatgaatcgc gggatctgcc acttcttcac
     6661 gttgttgagg attttaccca gaaaccggta tgcagctttg ctgttacgac gggaggagat
     6721 ataaaaatcg acagtgcggc cccggctgtc gacggcccgg tacagatacg cccagcggcc
     6781 attgaccttc acgtaggttt catccatgtg ccacgggcaa agatcggaag ggttacgcca
     6841 gtaccagcgc agccgttttt ccatttcagg cgcataacgc tgaacccagc ggtaaatcgt
     6901 ggagtgatcg acattcactc cgcgttcagc cagcatctcc tgcagctcac ggtaactgat
     6961 gccgtatttg cagtaccagc gtacggccca cagaatgatg tcacgctgaa aatgccggcc
     7021 tttgaatggg ttcatgtgca gctccatcag caaaagggga tgataagttt atcaccaccg
     7081 actatttgca acagtgcccc ccgccctgca ggaacgcctg cgccaactgc atccctacga
     7141 actcccggag ctgctcgcgg tcgaagccgc gtccggcctg cccgaatacc tgcaatggct
     7201 ggccgccgag agccgaccgg taaactgagc caatgaccgc atccacgatc cgcctgcgcc
     7261 gctggctggc cgggctcgcc ctgctgcttg cgctgcccgc gacctcggcc gtcgcccagg
     7321 acttcgaact gccgccggtc gacgaggtct tcgtcctgtc cgcgcaggcc accgcgccgg
     7381 accgcatcga ggtgcgctgg cggatcgccg acggctatta cctgtaccgg caccgcacct
     7441 cggtcaaggc cgatgccgcc ttcaccggcg cgaccatggc gctgccgaag ggcaaggcct
     7501 accgcgacga attcttcggc gacgtcgaaa cctaccgcaa ggaattgctc ggcaccctca
     7561 ccggcacgcc cgcggccggc gcgagcgcga ccaccctgac cgtgaagtac cagggctgcg
     7621 ccgatgccgg cgtgtgctac ccgccgcaga cccgcaccct gaaggtcgcg ttgccgggcg
     7681 aagcgggcgc tggcggcttc ggctgtaagg cgcgcgggct gcatgattat gtcgtcaaga
     7741 acggctctgc cgatcatccc aacgccgagg tgaaattcgc actgggtgat gtggtcaaca
     7801 ccatgatcgg ctgcactaat ggtgaaacga tcatgctgtg ccacgacacc tcgctgccgc
     7861 gcccctattc tctcggcttt cgggtgcaag gcaccgaggg gctgtggatg gacgtcaaca
     7921 agtcgatcta tctggagggc aagagcccac agccgcaccg ctgggagcct gccgagggct
     7981 ggtttgcgaa atacgatcac ccgctatgga aacgctacgc cgatctggcg gcaggggccg
     8041 ggcatggcgg gatggactgg ttcgtgatcc acgcttttgt cgaggcgctg aaggccaagg
     8101 ccccgatgcc aatcgacatt tacgacgcgc tggcctggag cgcgatcacg cctctgtcgg
     8161 aacaatcgat tgctgagggc aatcgcacgt tagattttcc cgacttcacc cgagggcagt
     8221 ggcgcacccg caagccgatc tttgcgctga acgacgccta ttgatcgacg cgatttaggc
     8281 caagcgcacc gcaaaggcga aattggtaat cttgtcggta tccttgacgc ccggcgcgct
     8341 ttcgacgccg ctggaggtat cgaccagcgg cgctccggtg cgcgcaatcg cctcggcaac
     8401 attcgtcgga tttagcccgc ctgccagccc ccacggcaag gcaccgcgat atccggccag
     8461 cagcgaccag tcgaacgcca accccatgcc gccgggcagc gcgcctttgg gggtcttggc
     8521 gtcgaacaag atcaagtccg ccgccccggc ataggctgcg gcgcgtgcga catcgctggc
     8581 gctggcgacg ggcagcgcct tccacaccgg cttgccaaac cgcgcgcgca actgggccac
     8641 gcgttcgggc gattccgaac cgtgcagctg cagcgcgttc agcttggctg ccaccagtgc
     8701 gtcggcgatg acagcatcat ccgcatcgac gaacaaaccg accatggcga tctggccagc
     8761 tgcgcgcgat gtcaaagcgc ccgcgacatt cgacgtaacc gcacggggcg acgctggata
     8821 gaacaccaac ccggcatagt ccgcccgcgc cgcgatggtc gcatcgagcg cctcgggtgt
     8881 gctgatcccg caaatcttga ttttcgcggg catgcggtca gtcggggttc tggatcagcc
     8941 gcaccagcgt gcagtcggga tcgatcaggt agccgatcct caggccgctc gcctccagtt
     9001 gcggagcttt gaagcgcggc cagccggtgc ttttttcctc ggctcccgcc gcgttcacca
     9061 atgccaccat ggcatcgaga tcatccaacc gcaggcaaca gccgaacgag ctcgtagctg
     9121 ggtcgaggtc aggatagggg aagaattcga gctgcaaacc gccgcgctgc aggatcatcc
     9181 agccgcgatc cttccaactc gtcgcaaagc ccagcttcgc ataaaacgcc tctgtcacat
     9241 cgaaatcgcg cgatggcaga ttgggggtga cgtggtcagc catggctcag cgcagcttgt
     9301 cggccatgcg ggccgtatga gtgattgcgg cgcggctatc gggggcggaa tggctcatca
     9361 cgatcatgct ggccttgggg aacgccgcac caaacgcgcg cgctgacgcg gcgtagtgct
     9421 cagtgtcggc atcaccgaga ttgccgagcg acttggcctt gctgtccttg atcaggcagc
     9481 caccaaaagc gatgtcggtg ccgtcgatcc caacggtgat attgtcactg gtgtggccgg
     9541 ggccggggta aaataccttg agcgggccaa agttgggcgc ggttgctggt tcgacccagc
     9601 cattggcggc gaaagtcagg ctgtgttgcg ccgcaaccag cccctcttgc ggggcaagct
     9661 ggttcgacaa cgcattggca taagtcgcaa tccccgccgc atgcagcgcg tccataccgc
     9721 ccatcttgtc ctgatgcgcg tgagtcacca ccgccagcgc gaccggcagg ttgatctcct
     9781 gcttgatcca gttgaggatc tgggcggtct ggtcatcggt ccaggcggta tcgaccaaca
     9841 gcacgcggcc gccatccctg acgatcaaac cgttggaagc gactgccccg aaacccggca
     9901 tgtcgagata ggaagtgtgc tgccagacat tcggtgcgag ctggcggaaa accagatcgc
     9961 caaaccgttg gtcgccagtt tccatttgct ggccaatcgt cgggcggatt tcaccgggca
    10021 tgcacccgct cagcatcaat gcagcggcta atgcggtgct cagcttcgcg accgggtgca
    10081 taatattggg caattccatc aagttttcct tttattcagc attaaaaacc ccgcaaatgc
    10141 gaggcctagt aaatagatga tcttaatttg gttcactgta gcaaaaatat ggggcgaatt
    10201 caaacatgag gtgcgacagt ttcaaaagcc atatgataat caacaagctg agcaaatttc
    10261 tctaaggaag gtgcgaacaa gtccctgata tgagatcatg tttgtcatct ggagccatgg
    10321 aacagggttc atcatgagtc atcaacttac cttcgccgac agtgaattca gcagtaagcg
    10381 ccgtcagacc agaaaagaga ttttcttgtc ccgcatggag cagattctgc catggcaaaa
    10441 catggtggaa gtcatcgagc cgttttaccc caaggctggt aatggccggc gaccttatcc
    10501 gctggaaacc atgctacgca ttcactgcat gcagcattgg tacaacctga gcgatggcgc
    10561 gatggaagat gctctgtacg aaatcgcctc catgcgtctg tttgcccggt tatccctgga
    10621 tagcgccttg cctgaccgca ccaccatcat gaatttccgc cacctgctgg agcagcatca
    10681 actggcccgc caattgttca agaccatcaa tcgctggctg gccgaagcag gcgtcatgat
    10741 gactcaaggc accttggtcg atgccaccat cattgaggca cccagctcga ccaagaacaa
    10801 agagcagcaa cgcgatccgg agatgcatca gaccaagaaa ggcaatcaat ggcactttgg
    10861 catgaaggcc cacattggtg tcgatgccaa gagtggcctg acccacagcc tagtcaccac
    10921 cgcggccaac gagcatgacc tcaatcagct gggtaatctg ctgcatggag aggagcaatt
    10981 tgtctcagcc gatgccggct accaaggggc gccacagcgc gaggagctgg ccgaggtgga
    11041 tgtggactgg ctgatcgccg agcgccccgg caaggtaaga accttgaaac agcatccacg
    11101 caagaacaaa acggccatca acatcgaata catgaaagcc agcatccggg ccaaggtgga
    11161 gcacccattt cgcatcatca agcgacagtt cggcttcgtg aaagccagat acaaggggtt
    11221 gctgaaaaac gataaccaac tggcgatgtt attcacgctg gccaacctgt ttcgggcgga
    11281 ccaaatgata cgtcagtggg agagatctca ctaaaaactg gggataacgc cttaaatggc
    11341 gaagaaacgg tctaaatagg ctgattcaag gcatttacgg gagaaaaaat cggctcaaac
    11401 atgaagaaat gaaatgactg agtcagccga gaagaatttc cccgcttatt cgcaccttcc
    11461 ctaacactct tcacttattt atttaaaatt tagcgacgtt aaaagacaat taagtatttt
    11521 tagataatgg ggttctaggg attttccgtc caaaaacgac aaagtgctct ggaggccgcg
    11581 ccgtccgtgg cctccagagg ggtattactt ttcgctgacg ggtaaatatc cctcgattga
    11641 gcgcataagc tcctccagat ctggcaattt ttcgctcaat tcgaagtggt aagtcccctt
    11701 gaggttaatg ttgtgccagg ccacagggga tgcctgtttg acgatatcta ttctcttggt
    11761 atctccttgg tattcgaagc tggtcaacag ctggctgagt atcctggagt tgaagtaaac
    11821 gatggcattg gtgaccaggc gagcgcactc attccatagc tggatttctt cgtctgaact
    11881 gccccggaac tgatccccat tgacgctgct cacggcccga cgcagttggt gataggcctc
    11941 tccccggttc agcgcgcgct gaacatagtt tcttaaactg gcatcatcga tgtagcacag
    12001 tagataattc gctttcacca ggcgattgta ttccgtcagg gcttccagca gcgggtgatt
    12061 gcgcttgtac tccgagagct ttctcaccaa ggtggcttgc gttgttttcc gctgcttaag
    12121 tgatactgca atccgttgga tggtatccca gtgctgcgca atacgatggg tattgattgg
    12181 cttttttaag cacagctgaa ttcggtgttc tttgtcttcc ttgacatcaa acatgtcatt
    12241 gatcactttg ccaacctggg catagcgtgg ggcaaactgg tatccgaaca gatccagtaa
    12301 cgcgaagttc acatggttca ccccatgggt atcggttgag agcacatccg gaatgatgtc
    12361 tgacgtattg ctcatcaaca aatcaaagat gtagtgcgat tcatgttcgt tggcgccgat
    12421 cactctggcg ttgatcgcag cgtgattggc gatcaaggtc atggcagaaa cacctttttg
    12481 agtgccaaag tacttcgacg aataacgggt tttgaaggtc tcgcgccggg cttcgaactt
    12541 ttgaccatcg gcactggcgt ggatcacatc ttcctggatg ttgtagtacc ggaagatggg
    12601 tagcttggct gtcgcgttat tgatgttgtc gttagcagca ttcaatgttt ccaggcgaag
    12661 atagttcgcc tggatagtgc tgagctgatc ataggtacga tcagagatct gtgccatgcc
    12721 gtaaatgcct tgattggttg cattgccgac cagaattgcc aacaggtcat attcatggga
    12781 acggcttctg gattgggaac ccagcacatg agcgaagcag tcaatgaaac cggtgtcacg
    12841 atcaaccatg cgcagtacat ccgcaatccc cgttgtggga atttgctgga agaagggatt
    12901 gttgaccaga tgatgtttgc tggccgaagg caggcgccag aagcgtttac cctgcggatt
    12961 acgcaagatg atattccggt tgtcttcctg ttcaagatat tcgccgactt cgtacaaacg
    13021 ggtatccaat tccatggcca tctgtttgat cagcttttca ggctcctccg ctaattttgt
    13081 aaaatggctc tgttgaagca gcgtatattt gttttttcgc caatgttccc cgtcgatcag
    13141 gtcggcgtcg agtgcccggt atttagtgat atcaggcagc gtcagctggc cattcaggcg
    13201 atcaggaatc tgttgataga ggaaccactc ataacgatcg atcaggatat tcccttcacc
    13261 atccagcagg aattcacgtg attttttgga aaggagtctg gtgtcggcag tttgcaactg
    13321 agcgtcctgg ccgttgagtt cgttttgtgt tttcgccaag gcggccgcta agtgctgggt
    13381 gccgtcgcag ccttcgaagc gcagacatag gaacaactct cgcagcaaac ctttccgcag
    13441 actttctttc tcgtcgcagt actgccacat ggcttcatcg accgatcgtc gctgctcgtt
    13501 caggaagaga catacagatt ccagatccct tttggtcagc aggctcagtg cttgctgtct
    13561 tactgttgca aacggtagtt gcagatcaat gctgtcatca atgaacaggt gcagtacttc
    13621 agctgccttg ctgacatttt tagctgcttt ttgccaatcc ttaaacaccg cttcctgcgc
    13681 ataatccttt gccttctgtt tggtctgtct gacatgatgc acaaagccat cggcaatacg
    13741 ttccagcgct tgctgccatc gcgtttgaag atagcacaat aaatacagcc attggctgcc
    13801 tacggtttga cgtttcagtt tggcaccgta gtagtcgact ttctctgcca ggtgttgcag
    13861 atttttctgc gacagtgata gcgtgctcaa cagcagatcc acttccggca tccaatgctg
    13921 gatatggcga tagacaatca gttctttctc caactcggtt ccggtgaagt tacgagccga
    13981 ttgtcgcaac tgtcggaacg gcagtggacc tgtgccgttc acgagctccg ccagtgcttg
    14041 cttaagaccg cgtgacattg cacgctcaag gtgcgcggcc atgtgttcct gttcgtctcc
    14101 caccacctga ctgatgatct tttgcagcgt gctgtaggca gggattgcga tcttctgccc
    14161 cgaacaatat tcattggccg catcgaagag gtgcctaggc gctgtccagg ctctggcttg
    14221 ctgggataag taatctctca acgccgctcc atggtctttg acattccagc gctggtagtt
    14281 gcagagctgg aaaacacgtt ggtaaatccg ttcgttctct tttggcgtga gattaaaggg
    14341 tctacagcct gggcctggta gaacggtttg ataaacgtat ttgaggtcct gcttgatctg
    14401 atgaaagccg ggattcagca ccaccggctt ggctttgaaa tagcccagca gtaccaccag
    14461 catgtaacgc tggccccgat gacggaggct tttagcgatc gccagttcct tatcgttcag
    14521 cgagaaaaag aagcgttggt cggcggaggt gaaagcgggg ggtccatata actcatcttg
    14581 ttctgcctcg gacaagattt ggacacgttc ttcgaatgcc atggatttag cccaaaaaga
    14641 ctaaatctta ctcaaacaga gcccaaatag ggatctcgaa aaaagtaata cccctctgga
    14701 ggccacagac ggcggggcct ccagagcact ttgtcgtttt tggacggaaa atccctagaa
    14761 cccctcagtg ggacgaaatg atccggaccg ctggctccct gaagctgggc aaagtacagg
    14821 tttcagtgct ggtccgttca ttgctgaaaa gtgaacgtcc ttccggcatc gcagtgaact
    14881 acctccacac ataaattgtg cttcagcgtc catcgaaatg caaaaaatga aaggctatcg
    14941 tggctgtgat ctggtgcgtc tgcgaccgga gacaacggat tcgcggctaa cttgggcgga
    15001 aataaattcg ctacgcgaat ggcctggcag ggggcgcgag cgctgtttta cggaatatac
    15061 aaaaaaagca cctcccgtaa acgggagggc ttcggcgatt caggaacggg aattttattc
    15121 tgcctctggt gtgtcgcctt ccatgccctg ccgggcatca tggagccagc ggcggaggtt
    15181 actcattctt tcccggtttg cccggctggg actttttccc ctgttaccgc ttagtatact
    15241 ccagactctt aacccggcct cgttagtcca gtgcaataca atttcccctt tgctgttaaa
    15301 tcccagcgaa aaccggacag ctccccgcct ctgttctgca ctgataaaat ctaaaaactc
    15361 ctgttttttc atagcacctc ctgtttttct atcagtgctt ttgtttcttt cttttccagg
    15421 gcttttctga gtaatgccat gtactcagga aaagcagaga atggcatcaa gggaaaaacc
    15481 ggacgcccac ccttttcaac agtctgtatt gctgataaca tgcgttccga cattttatat
    15541 tcctcgcgag ggaattgagt gtcacggtat caggttgcct ccacaacctg ataccacccc
    15601 taattgatta actccgcagt tctcttatcg cttcattttt ggcttcctcc agttctttaa
    15661 gggtatatgc gaaattcttc cagttaatta cttcgtttat aacctcagat ttacttaaac
    15721 cacactcatt aaaccaaaag ttaatatttt tcttgaggga atttttcgcc gtcagttcct
    15781 cggacaacaa ttcactaaca gacgtgataa cataaccacg accgcgattt ttatcttcga
    15841 aagaatgaac ggcaaggaag agagtttctg aatggacaaa agcagagcag gtgatttttt
    15901 ctttcttagt gtttaaagcc tggaaagtga taacatacgt gttcatttta gtctcccgcc
    15961 cgtttgggct actggatcat ggtaaggaac tattcccgac ctacaaataa attataccat
    16021 catatgatgg taatgcaatt tatttagtca ctttatcctg atttttttct ctcttaacga
    16081 gctggtaatc tggatgttca tcagccagga gcaaaagtaa ttcatacgta ccagcggcta
    16141 aaccacgaga cgttttaccg gatgtttctt tggcttgcca ggctgataac gtaaaaccaa
    16201 accgttcagc ggcttcctgc tgcgtaaagc cagctttaat acgtgcttgt ttcacctctt
    16261 caggtgttgg cttaaaactc atgattttgt accttcacaa tagtatctgt atagaatttc
    16321 aataaaattg gatcatcaat ttcatcttta acgttcgaga attcttcgta ataaaatgat
    16381 ttttggaaaa caatcttttt agttgttttt ttatccgctt ctttagagcg taccttcatc
    16441 agtttttcaa gttcaataaa caaacgtgtt gcatcttcag acacaacaat cctgtatgtt
    16501 acattacctt tgtttttcct gtcgctcagg acttcattca ttttttgcct catagctgtt
    16561 taataaaccc cgctaccttt atgagctgat ctacactcag gccacgaatt accatttcat
    16621 atccgtcgcc ccgttctgat acgttaccat ctaacccatt ctcaacttta aacccggtca
    16681 atgtcccatg ccagctttca agatgcacta aacgagatag cattcctttc aggatcagtt
    16741 ttttctcgcg tttttgctgt aactgttgtt catactctcg cgccatatct acattatcta
    16801 aagcatccga caggattttc ttttcaatat cggcggcgat ttctacaggg ttacgctctg
    16861 gcgatactgt gcaagtatgg taaggacttc tccagctgcg actatctacg cttccaatga
    16921 taactaacct tcctttctcc attcgaatat gtatagagta atttttaaaa tcaggtgagg
    16981 ttagcttaat cctgtactgg caatcatcga gcagatttac acgccagccg ttccccagga
    17041 ttcgacaaac gatttcaaac accggtttat accgttcaaa gaaatttttc tgttctttca
    17101 tcgattcagc cttttgaact caataaaaaa gccgtaaatc gaattacggc agttttaaga
    17161 ctattcatca aagtgtccat catcacttgc agcttcctgg gcttcgcatt cctgctgata
    17221 tgcttcttcc ttcgcaaaaa gatgcgccca tccttctgcg tttaagccac ggtgcaagac
    17281 tgaaccattt tcattgcatt ctttggctgt aacttcgatc tcatccgggc aaatgtaggc
    17341 tccgtaactt tcaaaaatgt ttatcagctc cgcttccgtt atggtcttgt ttttcatcaa
    17401 cgtgtctccg aatcaatctt tgccatgttc tagggggctt tcgcccccat tccggttatg
    17461 cgcttgcttc tacacgtgtc cagcctgacg ccttacgttt acccgctgta ccatacattt
    17521 cacgaatttc ttcaatgctg tgttctttac ggttccagcg gcttttgtgt tcttcaggac
    17581 ggtaaaacca ttgttttttc ttagatgccc acttacagcc catttccttt aaaatgtctt
    17641 tgtgttcttt agtttctccg ctaatccaga cccaattacc aataacttca tagacaatcc
    17701 ctgtaaggcc ggaaagcgta ttcagaactt tttccagatc ttcaccgtag ttgtaacgtg
    17761 cgttttcatc agtgctttga aactgattga ttttatcaat gttagccatg agaaaatcaa
    17821 acgcagcatt tactgctttc atcagctcgg cacccaatgg attgcggtct ggatgatatt
    17881 ttaaagccgc ttttttgtat gccgccttga tgtccttttc agtcagatca ccggataaac
    17941 caaaaacgtt taatgcttcc tgaatattca tttttcgctc ccgcccgtgt gggcttctgg
    18001 aatctggcag ggaaccattc ccaaccaaca aattcattat accatcaaat gatggttatg
    18061 gaatcatttt taatgcttta cattgtaaag attacataaa gatgtatatt gctttaccgc
    18121 gcatgaaggg atttccgaaa gaggcgcgaa ctgtagttac ataatgcgct gtcgtaacat
    18181 cgcgccggag acgttcgcca ggactggcga accaacaagc ccgaatgaga gcgataaccc
    18241 ccctcacccc tgccaggcca atttctgact atcagacgat gtttagcctg tcgcagttag
    18301 cgcgtgagct tgcgaacggt acgccgggtc agtgtgaaac actggcgcgg ggcgctgtat
    18361 ctgcgcgtta tgagatgcgt tagcagcgaa ttacggggcg ggttgctgaa accgattgat
    18421 gcctgacagc aaaaaatgaa tccgggcgcc agctgctgca cgaaaattgc cagcaaaaaa
    18481 cacttggcca tcctcgccgg tcgtgaaatt ttgctggcgt aagaaataat ccccccggta
    18541 tgaggggctt gtctgaaagg ttagtggttg ggcttactga gagtgaactg taacccggct
    18601 actgctgcaa gctgtgcaag tgttgtgatg gtcgggtttc cgttcgggga taatgcgcgg
    18661 tagatactct gacgagcaag gccggatttt ttggccgcct ctgttatacc ccctgattag
    18721 ggatcaggtt aaaaacgagc tgtatgacgt tctaagcgca ttttacccgc tccgttgaac
    18781 catgaccggg ttaaagcggt taaaacgcct ctgagggctt ttgagagcat ttaagaattg
    18841 gatcggaaaa ggatcccgtc tggatctttt agagagatta caccgctcgc cgcagccgaa
    18901 cgacagggcg aagcccgcga gtgagcgagg aagcggaatt tccacggggt ttcaatagag
    18961 cacttacgcg ctaaggttaa tatttgctca atttttggtg gtgcagtgct cagggaggcc
    19021 agacggatct atcctctgga tttatgctga gttatccaca gacgctgtgc attaaaagcc
    19081 ttatattttc ttcttgatct taaaaactta aaaacttagc tcgcttcaat tacctgaaaa
    19141 ttatggaaaa aaattgctaa aggtgagagg atttttcacg taaggtgaga ggatttttca
    19201 cgtaaggtga gaagattttt aagttaaggt agttagattt ttcactaaag atgagaggat
    19261 ttttcacgta aggtgagaag atttttaacg gtttccacag tttgactgaa catcaagtga
    19321 aacatgcggt tgttgctatc tttagatatg aagatcctca gatcttcata tctaaaggtg
    19381 agaggttttt taattaaagg ttgtattgtt gtcttgaatt acaacctttg tggggttatg
    19441 atttgcctac ataggaaagg ttatatgagg cttatcgtga agacagtaac gggattaacg
    19501 aaagttagac atagaaatga agttggggta actcttgcat ccctttccct ttcagcaaaa
    19561 agagtgcttt ttctggctct ttgccagatt gatacaaagg aaatgttaga tgatgatatt
    19621 ttggaggttg atgctgactt tttttcaaaa gctacttctt tagataaata tgcctcttat
    19681 gcagctctga aagagggagc taaagttctt tcttcaacta cgttagtttt aaacagagat
    19741 gatttaaaaa atttggctga tgaacttggg atactatcat ctaagaataa aatacctgat
    19801 cgcttggatt taaacttaac agaattctgt gcctattacg atcatcttgc aactgtacgg
    19861 ataaaattca caaatacagc taagcgatat ttttctaagt tgattggttc tgaaaataga
    19921 tataccactc aggtattgaa atcagttgtg ttgttgaaca gtgtaaactc aacaaacctt
    19981 tatcaagtca ttaggaaata ttacagtcag aatagttcaa aaaaatcttt tgatatatcc
    20041 gtggatgatt taaaagagga aatgggactt tatactattg aggaagggga gaagaaatat
    20101 aagtatccta aatactcatt ttttgttcgt gatgttatca ataaaagcat taatgagata
    20161 attgagaaaa cggaaataaa tcagttatct ttctctgttg ttgggaaaaa agggagaatg
    20221 gctcacatgc ttagatttga gtttagtata aatgaaaaat cctcatcctt ttcggaagat
    20281 gatatggcat ttttagagga gtttgacaaa gtcgttccac caaaaaagaa taagtgaggc
    20341 aaaacatggc taaaatatat gagtttccgc agggagccga acgaagtaag ctgaaaaaag
    20401 aaatcatccg ggaacgtaaa aaacgattgc gagaaacgaa cggtaacccg gttatccggc
    20461 acgctaaatg gttctggttt tatctacgtc ttgctacggc tggcgcactg catttagtct
    20521 ctgttatttc tctggcagtc ctgggggctt tcagtaaagc tattttctgg attggtggaa
    20581 tgctctgtgt tgttacatgg ttccaccttg agcgccagtt ctggacgccg caaaatttca
    20641 cgattccagt aatcgtaacg ctgtggggat tgagtttgtt tgccactccc ctgatggagc
    20701 tgcttaacaa aaaaatgccg tggtatcgtc ttctggttcc tgatgcaaag cacactagca
    20761 ctgaggcaac caatgatgat cagccgtgaa gcaacaatgt tatccagtcg gcttgcagtg
    20821 cttctttcag ccttttatca tcggttaatc atagcgcacg aggcgagttc ttttcactgc
    20881 gatgcaggat agggcaaacg ccgcaaaatg acgtctctga cgccattccg caacgtttgc
    20941 ccggtgacct acagtcggtt cttgttggag agagttatga aatatcaggt taaagagttt
    21001 attaacgaaa aatattctaa ggctgttaat attttaaagg ataaccttaa agaacactac
    21061 catatttttt atggtttgag attaagtgag attctttttc ctgccagcga atacggctct
    21121 gaaatgtttt ttcaggagtt tgaagcgatt aacagtgtaa tattgccttt ggtgattttt
    21181 gatttgatag accgaaagcc gattatggtt atcggcttcg gtgaagtatg tggagttgat
    21241 tcacttgttg attctggtat agaagttgtt tctttagacg gtttaagcga tctgctactg
    21301 gttgaaaaac tgacgccatt atttaactaa acctctggat aactatcttt tcagttttcc
    21361 agtaagattt tttctatatc tgaaagcact attttttcaa tgctttctat atagtaatgc
    21421 tcattaaaac ctgtcatttc tgtaaatttt agctctgcat catctttcga ataagcaata
    21481 acaactctga aatcattttc ccacaaatcc cacctgtatt tgtcttttat acgaaccctg
    21541 tacaatcctt tttggatagt gccatctttt ttctcttcct gtactttttt taatttttca
    21601 ttttgcacct gttgttcaag ccatgattta ttcataaatc ccccacggtt aacgtcttta
    21661 ggctcggttt ttacttaacg aaatcttccg gttttacacc tgtttttacc ttcatatact
    21721 tgccctcccc ccttagcttc ggctgaagtt cggtaaagta ccatccggca acggtaataa
    21781 tgcctaaaaa tacaaaaata gcaggcttca gaacatcaat agctgataca gcgcataact
    21841 caatattgag attagtacaa gttccctcat caggtgcata gaacccccat aagcctatac
    21901 ctataaggaa catccccaat atcggttgga tgtataacaa gtagatatta ataagagttt
    21961 taatatatct gaatatgaac atttttcttt ccttaggttt ctttctattt tggatttcca
    22021 attcttaacc aatgtgatgg ttcgacaatc cattctccgc agtcataggc aacggcctta
    22081 ttatgcctgt tagcgaacca tactaaccag gctaataatc gctgattgcc gctgtatttg
    22141 gtttatctct aaccatcaca acatatctct ttttcttagc cataacgcta ccctaatttt
    22201 gcagattcaa gcagccagtg gtttttcagg ttctcgtcca ggttatcgaa tgcggccagc
    22261 gctgccttta gaacggttgt cttgctctgg cctgttctct gcgcctccgc ttccaggatc
    22321 tcctcaaagt acgctggcag tctgaagttc atcaactttg gtttacccgc tacaggcgct
    22381 ctggtagcgc cggagataaa acgcgcggtt tctgcgtttg ttgctggttg ctgagattca
    22441 tcgatgttcg ggcggtttag ttttaaagcc atgaaaattt ccccttgtac ggtatgcatt
    22501 aattgtaaat atcatagtat ctttatggtg tatttacaat gtaaagattt cgatgaatat
    22561 tgttgatatt tctataaaat gccaatttcc tgtgccacaa gttcaatctg tgctttcgct
    22621 gttgaaaggc tcgatgcccg gctaacgtca tgtacccctg ccccttcatt acaggcgctt
    22681 tcatacacat ccagctcgga tatccgggtt ttcagaggtt gaatccagat gttgtccgaa
    22741 cgcagtaatt tatccagatc aatggccgct tttctgtggc ggggtttcgc tgagttgatt
    22801 ctggtgaaca gcacccacgg ttccagagct gcgttagctt tctgagcggt gcggattttc
    22861 tctgtaacac tggtcagtgt ttcgctttcg aaatcagagg acggcttaac cagtgtcacc
    22921 acgatatctg atactgtcag ggcgctacgg aactcctggc tgtcgtggcc ggggcaatcg
    22981 acaatgagaa cttcacacag cttactaagg cgcttaattt cgttgctgac gtttccgtaa
    23041 gctgcgtgaa ccgggatagt gagtaagccg ttatctgtcc gcttttcgtt ccagctcaac
    23101 agatcgtggt ttttatctgt cttcaggata attaccgact tacctttgtt gaccagcatt
    23161 gagcctgtgt tagccacgta ggtgcttttg cctaccccac ctttatctga tacgacaagc
    23221 aagattttac ccatttcaga atccctctct ttatgttgta aagctcatgt aaagatatga
    23281 atgtctttac atggtgtgtt tttcgtaaag atacttttgt ctttacagtg tctttataat
    23341 gcaatggctt taccatgtaa agcacaaata aagatatatt tatctttatg gtgtctttac
    23401 atggtaaatg ttgctgtgtc tttatgtgcg ctttatggtg taaatcttgg tgtgtcttta
    23461 catcatcttt atgttgtaaa tttttagtgt gacgttgtca ctatagggct ggggtctgtt
    23521 tgctggttct ttttgagtgt gccttccctg aaccaactga aatgggtact gtatgggtgt
    23581 gtctggttaa ctcaaaatga actggttccc tataatgact caaacagtac cgaaaggctt
    23641 tgtcagagct tacttacgcg catccacgac tgaacaggat gcaacacgcg ccctggacac
    23701 gataaatacc ttcgccatcg agcgcggcct gagcatctgt aactactaca ttgaaaatga
    23761 atcaggttct aagcttgaac gccctgagtt gttccggctc ctgaaagatt gtcagcaaaa
    23821 cgatatcttg ctggtagagg atgtggacag gctttcacgc ctggtagggg aggactggaa
    23881 cacactgaag aaaatgatcc ggcagaaaga tatccgggtt gtggccgtca acgttccgac
    23941 aacctggctc gcatcgggtc acaatgattt tgacagccga atgttttcgg ccataaacga
    24001 tatgttgctg gatatgctgg ccgccgtcgc caggcgagac tatgaacagc gccgggaacg
    24061 gcagcagcag gggatcgcca gggcgaaaag ggaagggaag tataaaggcc gccaggttaa
    24121 tcagtctcgc tatgacgcca taaacaggct gattgcgagc ggcagctcct ggagccagat
    24181 tcaaaaagtg ctgggttgta gccgggcgac tatcagcaaa gctgtgaagc aacagaccgt
    24241 taacaaaatg aaccatgaac ctgaaggtag ggagtagtta caacataata aacagtgtgt
    24301 tgaagaataa aactgattct ttatactgta tatgcatggg tcttccccga tcatggtggg
    24361 aaggctcaga acgccatatt cagctttccg tagtggaaca tcacccccag tttaaagcgc
    24421 tcccggtttc ggtatcccct ggcttttatc ctcagcagcc tgatcttgct gttaagtgcc
    24481 tccgcatttc cgtttgagac actgtgtcgc atcgcattca ggatcccgta cagccttttt
    24541 cggggtctga cgctcagtgg aacgaaaact cacgttaagg gattttggtc atgagattat
    24601 caaaaaggat cttcacctag atccttttaa attaaaaatg aagttttaaa tcaatctaaa
    24661 gtata
//
