LOCUS       NZ_CP059826            26581 bp    DNA     circular CON 20-SEP-2023
DEFINITION  Enterococcus faecium strain A15023 plasmid pA15023_P3, complete
            sequence.
ACCESSION   NZ_CP059826
VERSION     NZ_CP059826.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14675383
            Assembly: GCF_012933295.2
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26581)
  AUTHORS   Veeraraghavn,B., Vasudevan,K., Arumugam,A., Solaimalai,D. and
            Bakthavatchalam,Y.D.
  TITLE     Complete genome of vancomycin resistant Enterococcus faecium
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 26581)
  AUTHORS   Veeraraghavn,B., Vasudevan,K., Arumugam,A., Solaimalai,D. and
            Bakthavatchalam,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2020) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore, Tamil Nadu 632004, India
REFERENCE   3  (bases 1 to 26581)
  AUTHORS   Veeraraghavan,B., Solaimalai,D., Vasudevan,K. and Arumugam,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-APR-2020) Department of Clinical Microbiology,
            Christian Medical College and Hospital, Ida Scudder Road, Vellore,
            Tamil Nadu 632004, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method :: CANU v. v. 1.7; UNICYCLER HYBRID v. v. 0.4.6
            Assembly Name                     :: A15023
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 47.86x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/20/2023 03:31:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 45 of 105
            Pseudo Genes (incomplete)         :: 64 of 105
            Pseudo Genes (internal stop)      :: 33 of 105
            Pseudo Genes (multiple problems)  :: 30 of 105
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059826.1.
            Bacteria and source DNA available from Christian Medical College.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..26581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="A15023"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pA15023_P3"
                     /geo_loc_name="India: Vellore"
                     /lat_lon="12.9165 N 79.1325 E"
                     /collection_date="2019"
                     /collected_by="CMC Vellore"
     gene            complement(join(26274..26581,1..2044))
                     /locus_tag="HI843_RS14925"
                     /old_locus_tag="HI843_014925"
     CDS             complement(join(26274..26581,1..2044))
                     /locus_tag="HI843_RS14925"
                     /old_locus_tag="HI843_014925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="WP_000344083.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQV
                     ELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVYTP
                     YLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLNVNY
                     LEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGNSGNY
                     VRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKGLLSSA
                     GDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTTEELNNI
                     FSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAVDLDMLGE
                     EILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMSTGYSGNLG
                     FPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNYIAKYNQKVI
                     NQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRKIYDEYRNKLT
                     NSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWLGDLMTCWGEVK
                     KLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDSTALSALKTYYCDK
                     GAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFIDKIVNNSLGTDFT
                     YLDFIGDEGKVANGFSEKIIQFQENRSKLN"
                     /name="glycoside hydrolase domain-containing protein"
     gene            complement(2169..2858)
                     /locus_tag="HI843_RS14930"
                     /old_locus_tag="HI843_014930"
     CDS             complement(2169..2858)
                     /locus_tag="HI843_RS14930"
                     /old_locus_tag="HI843_014930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000718009.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFEE
                     EDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKNDIE
                     TTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFLRWK
                     SYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNPVAGT
                     YYVVQNI"
                     /name="hypothetical protein"
     gene            complement(2872..3042)
                     /locus_tag="HI843_RS15425"
     CDS             complement(2872..3042)
                     /locus_tag="HI843_RS15425"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_243354173.1"
                     /translation="MGDGKSELVSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELK
                     QIKETNSVELE"
                     /name="hypothetical protein"
     gene            3220..3900
                     /locus_tag="HI843_RS14940"
                     /old_locus_tag="HI843_014940"
     CDS             3220..3900
                     /locus_tag="HI843_RS14940"
                     /old_locus_tag="HI843_014940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<3950..4903)
                     /locus_tag="HI843_RS14945"
                     /old_locus_tag="HI843_014945"
                     /pseudo=""
     CDS             complement(<3950..4903)
                     /locus_tag="HI843_RS14945"
                     /old_locus_tag="HI843_014945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /name="IS256-like element IS256 family transposase"
     gene            complement(5040..5720)
                     /locus_tag="HI843_RS14950"
                     /old_locus_tag="HI843_014950"
     CDS             complement(5040..5720)
                     /locus_tag="HI843_RS14950"
                     /old_locus_tag="HI843_014950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<5795..6400)
                     /locus_tag="HI843_RS14955"
                     /old_locus_tag="HI843_014955"
                     /pseudo=""
     CDS             complement(<5795..6400)
                     /locus_tag="HI843_RS14955"
                     /old_locus_tag="HI843_014955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358225.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            6583..7542
                     /locus_tag="HI843_RS14960"
                     /old_locus_tag="HI843_014960"
     CDS             6583..7542
                     /locus_tag="HI843_RS14960"
                     /old_locus_tag="HI843_014960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222573.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHCLNRSRQTIHKVYLFF
                     KQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIRCS
                     ARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFKSITF
                     DCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDESF
                     IQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
                     /name="IS30 family transposase"
     gene            complement(7566..7862)
                     /locus_tag="HI843_RS14965"
                     /old_locus_tag="HI843_014965"
     CDS             complement(7566..7862)
                     /locus_tag="HI843_RS14965"
                     /old_locus_tag="HI843_014965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(7997..9490)
                     /locus_tag="HI843_RS14970"
                     /old_locus_tag="HI843_014970"
     CDS             complement(7997..9490)
                     /locus_tag="HI843_RS14970"
                     /old_locus_tag="HI843_014970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            10102..11055
                     /locus_tag="HI843_RS14975"
                     /old_locus_tag="HI843_014975"
     CDS             10102..11055
                     /locus_tag="HI843_RS14975"
                     /old_locus_tag="HI843_014975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            11027..11302
                     /gene="prgO"
                     /locus_tag="HI843_RS14980"
                     /old_locus_tag="HI843_014980"
     CDS             11027..11302
                     /gene="prgO"
                     /locus_tag="HI843_RS14980"
                     /old_locus_tag="HI843_014980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            11495..11749
                     /locus_tag="HI843_RS14985"
                     /old_locus_tag="HI843_014985"
     CDS             11495..11749
                     /locus_tag="HI843_RS14985"
                     /old_locus_tag="HI843_014985"
                     /inference="COORDINATES: protein motif:HMM:NF013677.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000199136.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYLP
                     DQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
                     /name="transposase"
     gene            12155..13316
                     /locus_tag="HI843_RS14995"
                     /old_locus_tag="HI843_014995"
                     /pseudo=""
     CDS             12155..13316
                     /locus_tag="HI843_RS14995"
                     /old_locus_tag="HI843_014995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            <13448..13615
                     /locus_tag="HI843_RS15000"
                     /old_locus_tag="HI843_015000"
                     /pseudo=""
     CDS             <13448..13615
                     /locus_tag="HI843_RS15000"
                     /old_locus_tag="HI843_015000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            complement(14088..14660)
                     /locus_tag="HI843_RS15005"
                     /old_locus_tag="HI843_015005"
     CDS             complement(14088..14660)
                     /locus_tag="HI843_RS15005"
                     /old_locus_tag="HI843_015005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(14676..15281)
                     /locus_tag="HI843_RS15010"
                     /old_locus_tag="HI843_015010"
     CDS             complement(14676..15281)
                     /locus_tag="HI843_RS15010"
                     /old_locus_tag="HI843_015010"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            complement(15479..16159)
                     /locus_tag="HI843_RS15015"
                     /old_locus_tag="HI843_015015"
     CDS             complement(15479..16159)
                     /locus_tag="HI843_RS15015"
                     /old_locus_tag="HI843_015015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     ARG             16839..18778
                     /name="tet(S)"
                     /gene="tet(S)"
                     /gene_name="tetracycline-resistant ribosomal protection
                     protein"
                     /tool="rgi"
                     /drug_class="tetracycline antibiotic"
                     /identity="99.84"
                     /coverage="100.78"
     ARG             16854..18775
                     /name="tet(S)"
                     /gene="tet(S)"
                     /gene_name="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            18866..19033
                     /locus_tag="HI843_RS15030"
                     /old_locus_tag="HI843_015030"
     CDS             18866..19033
                     /locus_tag="HI843_RS15030"
                     /old_locus_tag="HI843_015030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="WP_005228365.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITVI
                     TEPDAKTQSR"
                     /name="cysteine-rich KTR domain-containing protein"
     gene            complement(19547..19903)
                     /locus_tag="HI843_RS15035"
                     /old_locus_tag="HI843_015035"
     CDS             complement(19547..19903)
                     /locus_tag="HI843_RS15035"
                     /old_locus_tag="HI843_015035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_029756604.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLTN
                     IENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVTIG
                     KVIQAIYGEKCKFN"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(<19879..20061)
                     /locus_tag="HI843_RS15040"
                     /old_locus_tag="HI843_015040"
                     /pseudo=""
     CDS             complement(<19879..20061)
                     /locus_tag="HI843_RS15040"
                     /old_locus_tag="HI843_015040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(<20196..20405)
                     /locus_tag="HI843_RS15045"
                     /old_locus_tag="HI843_015045"
                     /pseudo=""
     CDS             complement(<20196..20405)
                     /locus_tag="HI843_RS15045"
                     /old_locus_tag="HI843_015045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /name="DNA topoisomerase"
     gene            complement(20554..23541)
                     /locus_tag="HI843_RS15050"
                     /old_locus_tag="HI843_015050"
     CDS             complement(20554..23541)
                     /locus_tag="HI843_RS15050"
                     /old_locus_tag="HI843_015050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="WP_000343406.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPAT
                     RLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTKLI
                     KSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITTFSR
                     FVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLADDSH
                     KEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKKLALLV
                     AFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSDIVDLVM
                     SSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYRKFRKFIP
                     DILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYYIHEYPEQT
                     NKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLLEQLDLPSSA
                     NEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKEDKSFRRRIQQ
                     LLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSESCNIGFSPVSK
                     EGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDGHMASADGIRYIT
                     PQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSLYLLEGFLNQPSEL
                     TPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDANAHYGELDTLSQNSI
                     NMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGKAITEYGKVYKTKHQL
                     RYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYDGMEEQLNALGLVTNAI
                     IYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVGKYTFRYEAELSNGKLRP
                     LNVEEF"
                     /name="Tn3 family transposase"
     gene            23666..24271
                     /locus_tag="HI843_RS15055"
                     /old_locus_tag="HI843_015055"
     CDS             23666..24271
                     /locus_tag="HI843_RS15055"
                     /old_locus_tag="HI843_015055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002321606.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERPE
                     FQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNEL
                     LDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRL
                     VFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
                     /name="recombinase family protein"
     gene            complement(24316..24483)
                     /locus_tag="HI843_RS15060"
                     /old_locus_tag="HI843_015060"
     CDS             complement(24316..24483)
                     /locus_tag="HI843_RS15060"
                     /old_locus_tag="HI843_015060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000824191.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCPK
                     CHRRYGVHGT"
                     /name="hypothetical protein"
     gene            complement(24517..24816)
                     /locus_tag="HI843_RS15065"
                     /old_locus_tag="HI843_015065"
     CDS             complement(24517..24816)
                     /locus_tag="HI843_RS15065"
                     /old_locus_tag="HI843_015065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="WP_000366408.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFLV
                     CGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
                     /name="BRCT domain-containing protein"
     gene            complement(24857..25474)
                     /locus_tag="HI843_RS15070"
                     /old_locus_tag="HI843_015070"
     CDS             complement(24857..25474)
                     /locus_tag="HI843_RS15070"
                     /old_locus_tag="HI843_015070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001224538.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFKR
                     PEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTASY
                     KQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPPEFP
                     AIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
                     /name="recombinase family protein"
     gene            complement(25799..26194)
                     /locus_tag="HI843_RS15075"
                     /old_locus_tag="HI843_015075"
     CDS             complement(25799..26194)
                     /locus_tag="HI843_RS15075"
                     /old_locus_tag="HI843_015075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002304891.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIVD
                     YFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKKKE
                     YNYIVKAKVSKRFIFNPKLEIYSVVIE"
                     /name="hypothetical protein"
     Typing          complement(7998..9490)
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttgaatcaga atttcttttt gctaaggtat aaacatttac cgcgtcaaca tcttggtata
       61 aatcttctag actaaatgtt ccacctgcag ccgtacctac taatgcaaat acaccttgct
      121 ccatttgtat tcctaatttc ttaacttcac cccagcaagt cattaaatct cctaaccaac
      181 ctgcaaagtc agaaacacta tcattgattg tgtcggctag aaacatctgt gattgtaacg
      241 tcacaattaa gtgaggcaaa cctattattg aaccagtatt aggatctata aaataattat
      301 acaggccctc gctattagtt aatttattcc tatattcatc ataaattttt ctatcatgct
      361 ctgttacagg agaagaaatg atgtcccatg acaaaccaga ataatttaca tatctataaa
      421 atgtcaaatg agggttccaa ggattatcaa gaccagcttg tgatagatat tgatacgcac
      481 gtaccatctg atttataacc ttctgattgt atttggcaat gtaattatca ttattagtat
      541 catttgataa ctcattaaat ccgctatctc tacccgatgt agcgattaaa tcgataccaa
      601 cagctccgtt gccacttcct atggtaaatt caacaaattg atcaaaagac cattgtctag
      661 gcataggaaa acctaaattc ccactataac cagtcgacat atctgaaaca aatgcaaacg
      721 aagcataccc gttattgatt atttgagaac aaacatttct tgttccgtaa acacccgttt
      781 gatacccgct atatgacatt acagcagata cccccttaaa atattctcca gcatatgcaa
      841 gaatttcttc ccctaacatg tctagatcaa cagcaaaata aataactgtt gttaatggta
      901 tatttagatt ttttgctgca tctatagcct tcttaccatc tgataagcca cgatcataag
      961 taaaataagc taatgctgca cctccatctt gatagatagg aaacacagat aaatttttag
     1021 aaaaaatatt attcaattcc tctgtagtta gatacttatt tcgttcatct tttccaattc
     1081 caacagtacc agtaagatat ctaccaacta tttttatatc attatcaacc aatgtttgga
     1141 tttgagatct agttaattgc gtagaagtat ctgcgccatc tgcagatctt ctaatatctc
     1201 cagcgctaga caatagtcct tttattacaa caacatctgc tatttcagta tattcaggca
     1261 ataccataaa ttttcggaat gccagtactt ctaaacccat atatttagtg aaaataccat
     1321 cgaatgtacc gtcttcaaaa taaccattaa catataatcc atattgaatt attcttacat
     1381 agtttcccga gttaccttca gacacaggat aagttttact agttgtccca ttaccataag
     1441 accctgttgc ttcactggga gaatatccta gttcagcttg taatgcaaaa attaatgctt
     1501 gatttgaatt tctttgataa ataccatcac aaggcattat tcccgtgtat tctaaataat
     1561 ttacatttaa ccattgctgc atttttctaa ttttactatc tccgccggga acaagaacaa
     1621 aagcactcat atcaaataac gctttggccc atttcgcatc caaaactcca gttacagcgc
     1681 ttccattaaa ccctgcatca gtctgcaact cttttacagc agtatctaaa tatggagtat
     1741 ataccccatc gaagccacct ggattaatcc ccttacacca aaaggcacct tgaataagaa
     1801 atacaatatt tttaggtaga tttttgcccc atttaggagt aacctgatta tcgtacattt
     1861 tttcagtggt aggtccaaaa ttagctacta gattagtaat accaagttct acttgtagtc
     1921 cttcaataag tccatagatt gtaggccacc ctgttcgccc attttctgga accttatcaa
     1981 accctgtaac attactgtat ttcttgttta gccatttctg agtacttaaa accatctcat
     2041 ccataaaaat cccctgcttt cttgccgaac atacgttcgt ttatgtgttg attatatttt
     2101 atattttagt gtttgtcaac aactaaaaat aataaaacag cacaaagaaa tctctttgtg
     2161 ctgttttatt aaatattttg aacaacataa tacgtacctg caacaggatt ataagtgtaa
     2221 taaataccta tattcattgt ccaaccaggc ccgtttggtg caaagtattt gaatccttca
     2281 cgagcataca atgccattcc ttgaatagaa ccagatttag ttgcgttggc ttgatttaca
     2341 tttcctactc ttccatcgtc aatgtaggat ttccaacgta aaaagttgcc tgtaccatca
     2401 gctggtttta cacccatacc tccaaaacgc catcccgcac cactaaatgg ctgtgattta
     2461 tagcttcctc ctcctgctag tacaagaagg tgtccgctag taccaacatc gggtggaaat
     2521 gctcctcgag gcataattgg agtagtttca atatcatttt tgaatttttc agcaacaatt
     2581 ttttttgctt ctgtcactga aactgaagca ggatcagttt ctgaattata tgaaccttga
     2641 attatatctg gattatccat agatacaatt ttagcttccc cttttaaaaa accaccttct
     2701 ggcaatgcaa gtactttatc ttcttcttca aaatcagcaa agtatcgtga ggcgtactgc
     2761 tctggatctg aaataacttc tttctcagca gcatatactg catttccaaa tgttaacatc
     2821 ataagtagcc caacagaaac accaaaaatc tttttcataa tgaatcttcc tttactctaa
     2881 ttccactgaa ttagtttctt ttatctgctt taattcattt cttttactat ttaaaagctc
     2941 ttttagatcc ttaatcgaaa tagcgttgga atcagtatta acatcaataa actgtctgtg
     3001 attttgttta taactaacta attcggattt gccatctccc attaattgcc caccagcaga
     3061 caagacaaca attttatctg agtcactaat tcctggaata ctttcttcta actgttcccc
     3121 ggataaatca ccaaattctt tatacggttc tgttgcaaag ttttaaatct actatcaaat
     3181 aaggtagaat aatagaaaaa gatagcagga ggaatgacga tgaatcattt taaaggaaag
     3241 caatttcagc aggatgtgat tattgtagcc gtgggctact atcttcgtta taaccttagc
     3301 tatcgtgaag ttcaagaaat cttatatgat cgtggcatta acgtttctca tacgacgatt
     3361 tatcgttggg tgcaagaata tggcaaacta ctctatcaaa tttggaaaaa gaaaaataaa
     3421 aaatcctttt attcatggaa aatggatgaa acgtacatca aaattaaagg aaaatggcat
     3481 tatttgtatc gagccatcga tgcagatggt ttaaccttgg atatttggtt acgtaaaaaa
     3541 cgggacacac aagcagccta tgcttttctt aagcggttag tgaagcagtt tgatgaaccg
     3601 aaggttgtag tcacagataa agccccctct attacaagtg cctttaagaa actaaaagaa
     3661 tacggctttt atcaagggac agaacatcgt accattaaat acctgaataa tttgattgaa
     3721 caagaccatc gtccagtaaa gagacgcaat aaattctatc gaagtttacg cactgcctct
     3781 accacgatta aaggcatgga agccattcga ggattatata agaaaacccg aaaagaaggc
     3841 actctcttcg ggttttcggt ctgtactgaa atcaaggtat tattgggaat cccagcttaa
     3901 atcatagata ccgtaaggga ttttattctt tatttaaaac tttgcaacag aacccatcat
     3961 ccaatgatgc gcaagctttt gaatattttg gttgatcgat ataatcatga atcaatcgat
     4021 ttttagcctc acgcgctaag ttaatatctg tgaacttaaa aattccttta acagcttctc
     4081 tgaaagattt tgaatttttt ttaggaatgg tggtaaagat atttcttagg aagtgaactt
     4141 ggcatctttg ccaacttacg ttggtgaagg attttctaat ggcagagact aatcctttgt
     4201 gcgcatcaga aataacgagt tccgtacctt gtaaaccgcg ttcttttagg tattcaaaaa
     4261 atgttgtcca ggtctcttcg ctttcgccac tttgaatcat gaagccgata atttcacggt
     4321 cgccatcttt ggttattcca atcgctatat gacagctttt tgagagtact cgattttctt
     4381 ctcgtacttt tatatagagt acatcggtca ttaagtaagg ataatttttt tctgataata
     4441 aacgattctg ccactcgtta accataggtt ctagctgttc tgttaagcta gaaacgaagg
     4501 acttagagac ggatttacca caaagttctt ccacaatttt tgatacttta cgagttgaaa
     4561 cgcctgatac atacatttcc aacattgaag ccatgagggc tttttcgttt cgttgataac
     4621 gttcaaacac tgtgggtgaa aaatggccat cacgtgttct gggtactttt aattctagcg
     4681 tgcctacacg tgtcgtaaag ctgcgctcat aatagccatt tcgttgactt tgtcggtttt
     4741 ctgttcgttc atattctttt gcttgaatat attctgttcg ttgattttcc attagttgat
     4801 taaataccgt tgttaaaata tttttagaaa cgtcatcctt tacagaatat tcaataatgc
     4861 tttgaatctc ttcgcttttc agtgtaaaat gtacttgggt catgtaaaag tcctcctggg
     4921 tatgtttttg tcgttaaaaa cattgtaccg taaaaggact gttatatggc ctttttactt
     4981 ttacaggttc tgttgcaaag ttttaaataa agaataaaat cccttacggt atctatgatt
     5041 taagctggga ttcccaataa taccttgatt tcagtacaga ccgaaaaccc gaagagagtg
     5101 ccttcttttc gggttttctt atataatcct cgaatggctt ccatgccttt aatcgtggta
     5161 gaggcagtgc gtaaacttcg atagaattta ttgcgtctct ttactggacg atggtcttgt
     5221 tcaatcaaat tattcaggta tttaatggta cgatgttctg tcccttgata aaagccgtat
     5281 tcttttagtt tcttaaaggc acttgtaata gagggggctt tatctgtgac tacaaccttc
     5341 ggttcatcaa actgcttcac taaccgctta agaaaagcat aggctgcttg tgtgtcccgt
     5401 tttttacgta accaaatatc caaggttaaa ccatctgcat cgatggctcg atacaaataa
     5461 tgccattttc ctttaatttt gatgtacgtt tcatccattt tccatgaata aaaggatttt
     5521 ttatttttct ttttccaaat ttgatagagt agtttgccat attcttgcac ccaacgataa
     5581 atcgtcgtat gagaaacgtt aatgccacga tcatataaga tttcttgaac ttcacgatag
     5641 ctaaggttat aacgaagata gtagcccacg gctacaataa tcacatcctg ctgaaattgc
     5701 tttcctttaa aatgattcat cgtcattcct cctgctatct ttttctatta ttctacctta
     5761 tttgatagta gatttaaaac tttgcaacag aaccgatcaa ttcgtcatat cttccaaaat
     5821 caacattgta ctcataacca agaagtgtcg gaatcaggtc aatttcaatt tctttttcaa
     5881 ttgaacgttt aataagtttc gtggatacat acccgacaaa aaagagaata atacccactt
     5941 caaacaaata catgtgtcca tttacaaagt gaataaacgt caataaaaaa tccttcactc
     6001 cttttgttgt tcttccagat tgttcaattt gttttattaa agtcgctaga attgcattta
     6061 caacaattaa atcgaatagg cttttgaaaa gttttcctgc tgttaatttt tgcctggtaa
     6121 attgcatgac taattgagta aaaatagaca atagcatgac aaaaatcaac gtcattagca
     6181 ctgtaaaaat gtctgatgct gcaatcctat tgggatcatt tatcaagtaa taagccgttc
     6241 caaatactcc aatcgagtaa acggttaaat caagaataag tcgtgccccg taactacaaa
     6301 gttttcctaa tggccataat tgcaataccc aaaatttctt tcgtttgcta tttcttttca
     6361 gaggaagcca ggtgtgttca atccagtcgt ccgatttcat ttcgatttct tccctaaatt
     6421 ctttccttta acgttttcct ttgctacttt agcagcgata ggttgctcaa tgaaccaatt
     6481 ttttaagtac gccgattgta aaattaagct agacaactaa aaaagtcatt tgtgctacac
     6541 tcaaaatagt tccgtccaaa gaattataag gagtgagtac aaatgaccta tacccatctt
     6601 acaacggatg aacttgtaat gatagagtct tatttcaaaa taaatcaatc tgttgcgaaa
     6661 actgcgcatt gcttgaatcg ttcaagacaa acgatccata aagtatacct gttcttcaag
     6721 caaggaaaat cagccttaga gtactatcaa cagtataaga aaaacaaatc aaactgtggt
     6781 agacgcccgc ttgttttacc tgaggaacaa tcagaatata ttcaaagaaa ggttgttcaa
     6841 ggatggacac ccgatgtgat tgttggtcgt gcagcgtttc ctattcgttg ttctgctcgt
     6901 accatttatc gtatgttcaa aaaggggcta tttaatcctt ctgacttacc gatgaaaggc
     6961 aagcgtaaac caaatggaca tcaagaaaga cgtggaaaac aagctttccg tcgctctatt
     7021 catgaacgtg aaaaagatta tagccaattc tcaaatgagt ttggtcacct tgaaggtgac
     7081 actatcgtag gtttgaaaca taaaagtgct gtaattacct tagttgagcg attatcaaaa
     7141 gttatcatca cattgaaacc gtgtggtaga caagcgattg atattgaaaa caaattaaat
     7201 cattggtttg aatctgtacc gaaaaatcta ttcaaatcca tcacttttga ttgtggaaag
     7261 gaattttcaa attggaaaca gatcagtaat gccaatgata ttgccattta tttcgctgat
     7321 ccaggaacgc cgtctcaaag aggcctaaac gagaattcta acggattgtt acgtagagat
     7381 ggtttattga aatctatgga tttcaattca gtagatgaat cttttattca atctgtcgca
     7441 tcgaaacgaa ataatattcc tagaaaatca ctgaattatc gaacaccttt ggaagtattt
     7501 ttgagttacg taagtattga tgatttgtct aacttaattt gacaattaag agtaaataaa
     7561 aactactact ggatatactt cttccttttt cttaactcgt tagctatttt atactcaata
     7621 tactcctgct ctaacacaca caaacaatca tatacctgat ccatagtctc cccagaagct
     7681 aaggacaacc catgaagaaa ctcaatcggc aaagaagcaa ctgttttttc cctggtaacc
     7741 caagaagaca aagtcccctg cttaaaacca taaagctcac agaacacttc cacagataat
     7801 cccaaacgac caatgataaa cacattaaca ggatgtgaat agacataatt ttttaacgac
     7861 atacaacttc ctccatgata cataagactg catacgcagt tataagtata ccacctacac
     7921 gtagctaggc aaagggagca acacctacag aagtatcata gatatattgt ataaggcaat
     7981 ttgcaccttt tatttttcaa cctgtatcta cttcaaaaag attcacttct ttaagagggt
     8041 tcaagggggt tgataattgt ctaaatgtct cttctactaa gctctcgttg agtccaaata
     8101 cctctgtgat ccttgttgaa taatctagtc tcttttcttt acttagttga ataaccctcg
     8161 cgaacaacgt tttgactgaa gcaatgatca ttccgccatt tcttcctcgt gttaccttgt
     8221 agaagacttt attctcctct cgtaactcat ttaagatctt atcaagtgtt cgcttgggca
     8281 tcgttagttg tgaagccaat tctttttttg acaggttcaa ataaggctca ctagcaagac
     8341 ttttttcgct tagataagcc aatagatctt ctttccattc atttttatga ctatattttc
     8401 tttgatctcg tggcttttta aatttccacc agccacgtcg ttgaatgaac agatcattat
     8461 tttttaaggt tggtgaaacc cattgctggc acaattcaat aatgaattct ctgcttgctg
     8521 cttgataatt accagaataa gcactacgta caatctttac taattctgct tcagatagcg
     8581 gttcctgtaa ccgttcgttg aatgtgaaca tattgtattc gcaagtatcc aatgcataac
     8641 ctgaagagta ataagctaaa gaaagcgtga aaatcacatt atttcgacca agacgtcctt
     8701 ctccgccgac gatgtttgct ttatgaagta acatatcgaa ccacggttca tctacttgac
     8761 gaatttcttt tttctcagga aagacaatta gttttcgttc tcgatcttct tttgtttttt
     8821 gatctgattc aagcttcatc gaccattgaa tccagtcagc aaaagaatac tgatagttca
     8881 tttctttaaa aacaatatta ttttcttgtg ggaatcgagc aattccgaag tggttacatc
     8941 ctagatccac tccggacaat ttttcagcca actgtagacg aattgttttt gaaatttttt
     9001 ttgctacatc gatcaccttg aaattgcttt tctttgtgac atagcctggt gtctttagta
     9061 caaaataaac ttgataacca tgatctgatt ctaaaattag cgttggcatg tagcccactt
     9121 gatctaaaca ggctaaaata atttcgcctt gatggttctc ttttgaatcg atatcaacta
     9181 caaatgtgtt gatttgactt aagtttttct cagaatgacc tttaaccact gttcgataat
     9241 catccgcata agtaccaaag cgataggtat taggtgtcca atgcgttagt ttcttttcgt
     9301 tctctaaaat agcttcttcc gaagtaatga ccataccacg cccaacattc attaattgct
     9361 tgctacggta cgcaaagata gcaccactcc tactggaatc aatatgacct gcaggtttca
     9421 tggtgctgtt tcgatatttg tatgtacgta agccgttttt aagaatagct gaataaattt
     9481 cgctcaacat cgattgtaac gtcctttctc aaacaaaaag agaacacagt ttagctttaa
     9541 tctcagccat agtatgtgtt ctctcttcag tgtttaagaa tatttaattt aagtacacta
     9601 aataaacgtt cttctgttga gttgctcgcc tttttttggt agaataaagg caatcggaaa
     9661 aggtatccga tcaactttta atataagtag ttggtagcta cttacatatt cttgagacga
     9721 gcgtgaacac atgtcctaac catgtgattc agaaataatt gattctgcta aaatcaatta
     9781 tttccgtctc ttttttttat gtaatttttc tgtttaaaga gtaccactgc ttttgctact
     9841 ttgtaaatag tgaattatct gtggtttcta tagaattaag tttacctctt ttcactctaa
     9901 attgtcaacg caaaacgcac aaatatattt tgacattttg aatatatctg atatactgaa
     9961 tatagcaaat atatttagta tatccactat attccttata aagtctgaat tcttatcaat
    10021 ttggagtata ttagatatat cgaatatatt aagtatatga agtatactaa atatatttag
    10081 tataggaaat tggagggaac tatggaaaac ttacggactg catttaaaac atcagataaa
    10141 ctaggaaaag ttgtaatgct tacaggtaga aaaggcggca ttggtaagac tacagacaat
    10201 gatttattag cgattgtttc tagtcaactt tttgaaaaag acgtgttgct aattgattat
    10261 gaccaacaaa gaaatactac ttccaacatt ggatcaacgt atcaaattac tagctttgat
    10321 cgatccatgt ctgcagcaat caaaaaaggg gactgggttt caggtattac tcaagtaagt
    10381 ccacatttat atattatggc tggctctcct ggatctgaag aacttaatga atacttgtcc
    10441 gaaaaatatc ctgatcgtcg taagagatca ttggccttca ttaaaccttt agaagaattg
    10501 agaaaaaatt tcgattatat ctttatcgac tgcccaccat caacagataa tgtggttcgt
    10561 gcattcttaa ctgctgcaga ttatattatt gcaatgcaag aattaaaacg gtacgcaatg
    10621 gaaggaacag aagattttat taataaagtt ttagttccga ttgtcacgaa ttttgaagag
    10681 tctcatcttc aaatcattgg aattttgcct gttcttttct cagtgcgacg ttcctctcaa
    10741 cacgcaaact atcaaaaaac aattgataag tatggtgaat caaacatttt taaaagcatt
    10801 gttaaaggct cggatcggtt agaaatgtat ggtgagaatg gtatccaatt aaatgattat
    10861 gtagatcgaa gatggtgggc tatttttgca gacatcttta cagaattaga agaaagaatt
    10921 gaatactatg aacaacatgg tgatattgaa ggatttgatt atacacctaa atatgctgac
    10981 tcaatggcca atcatatcct acctcttgga aaggagatta aactaaatgg cattattacc
    11041 aacgaacaaa gataagaaga aaattggtgc tgaagatatt tcaattaaag atgatattaa
    11101 tgtcgagtta ggggaacgaa agtacactgc gaaagaaaga aaaccagttc aagtagatcc
    11161 tcccgtacta aaaaccattc gggatcttag ttatgcaaaa gatattccta tgtatgaaat
    11221 agtcaaactt gcaatggacg cctatgttga tactttaaac gacgaggaac ggattatata
    11281 taatagacga tcaaaagatt aaaatatagt aagtatacta gatatagtaa atatatttag
    11341 tatacttact atatttttag ctttattaat cctaatcctt caaaatatgt gtattgtttg
    11401 ggggtataca acatttggtg ttagtatcaa atcttagaca gcttttcgta gagacaagaa
    11461 taaattaaac ttatctacga gaggatgaat ttttatgacc cgatatgaag aaaattttaa
    11521 acaaatgatt gttgaactga atcaaactgg acgttctgtt cgagggttag cgaaagaata
    11581 tggcttatct gaagcaacga tttacaaatg gaagaattta tatttacctg atcagtccac
    11641 aggactgact ggaaaagaag tagctgaact gagaaaagaa aatgctcgtt taaatgagga
    11701 acttgaaatc ttaaaaaaag ccgcagccat attctctcgg aaaacctaaa ttcgcttgtt
    11761 caatttattg aaaaatggtg taaggattac actgtttctt tgttgtgtcg gttattagaa
    11821 atccctagaa gtgtctatta tttttataag aataaaccgt tgacagctac agaaatcaga
    11881 aataataagt tgaaaaagaa gatttcaaca atttttttta cgaataaaca acgctatggt
    11941 gccacaaaga tccatcaagt tttattaaaa gaagggattt cagtatctct taaacatgtc
    12001 caaaagctaa tgaaacaatt aaatttaagg tcgattgtag ttaaaaaata tagacctcaa
    12061 aggtctaata aaccgatcat ggataggcta caattaacta gacagaaaaa ttaaggtgtg
    12121 tagactagaa gaaaacatac caggaggaat ttttatgtct aagagaacac gaagaacttt
    12181 ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta gctggaaagc cacgtgtaga
    12241 aatcattcga gaatatgaac taacggcttc agcatttgac aaatgggtaa agcaatttaa
    12301 aacgagtggt tcattcaaag aaaaagataa tcttacgcct gaacaaaaag aattgttaga
    12361 actacgtaaa agaaaccagc aattagaaat ggaaaatgat attttaaagc aagcagcgct
    12421 gatattcgga cgaagagaca agtaatcgat gcgaataagc atctttaccc tatatcagcg
    12481 atgtgcagaa tattaggtct atcacgtcag tcctattatt atcaatcaaa accaaagaaa
    12541 gacgaatcag aacttgaaga agtagtcgct gaagaattta tccgcagccg aaaggcctac
    12601 ggctcaagaa aaataaaaaa gccttatcaa aacgaggcat tcagatcagc cgacgaaaaa
    12661 ttagtagaat catgaaaaat agaggattaa aatcgagcta tactgttgct tattttaaaa
    12721 gtacatcatt ctacttgcaa tgaagccaaa acgacaaacg tattgaatcg taaattctta
    12781 agagacaacc cattagaagc gatcgtaaca gacttgactt atgtacgagt cgggaaaaaa
    12841 tggaattatg tctgtttcat tttggatctg ttcaatcgaa aattctcggc tattcttgtg
    12901 gagaacataa agatgccgtt ctagtaaaaa agcatttagc cgtatcaaac aacctctgac
    12961 agaggttgag attttttcat actgatcgtg gaaaagagtt tgataaccaa gctattgatg
    13021 aattattaac aacttttgac atcaatcgat cattgagtca taaaggctgt ccttttgata
    13081 atgccgtagc tgaatcaact tataagtcgt tgaaagtaga atttgtctat caatacacat
    13141 ttgaaacctt acaacaattg gatttggagt tatttgacta tgtcaattgg tggaaccacc
    13201 ttcggttgca cggtacactt ggctacgaga caccggttgg ttaccgtaac cagagattgg
    13261 cgcagcgaat ccttgataat gagctcggat gtgctaacgc tagcgaggca gtctaacttt
    13321 aactgttagc tcctgccgaa gatcgtcaca tccgaggagg ctcgtatcag gacaatcgga
    13381 atagcatacg gaaagaagtt ctgcacctta taaaatttgt caaaaaaact gttgccattc
    13441 cacctcattg aaaaaagaag aagtctacac gactagctac tcagattttg aagaagcaaa
    13501 tcgagcgcta tttagctaca ttgaaggatt ttataaccga aatcgaatcc atagctcgat
    13561 tcactatcta accccacagg aatttgaaga attagcaaaa gaaaaaatgg cttaaccgtc
    13621 tctactaaaa tgtgtccaag atattgactc aaatccagta atatcacaat aggaatgctg
    13681 tttattatat tagcagcagt gctgattttt atgatagtta tttggttctt aaatgaaaga
    13741 tctaaagaca atcaacaccg tagggatatg gagataaaat caatagagtc aatagattat
    13801 ttatcgataa taacactaaa aaagccacgt tcctaaacgt gacttacgct gaacgatatg
    13861 tgttgtttgg tagacgaaca aatcgttcat tataaatata tgatggtatc ctaatatagt
    13921 aagcgtggct agcatacctt taattacttt accttttaca gttaccatac acattttttg
    13981 agcagaaatc aagtaaataa aaaaatatta tatttcacaa catgctaata gactcatatc
    14041 tagaacgcat taagtattta cctgtctggt tcgctgagac ttctttttta actttcttca
    14101 attttcttct ttattctaaa aagcgtactg cgactgaaac cggttatagc ttcaacttcc
    14161 ttatacgatt tacctgaagt aagcagttca tatgcgtgcc tcttcttcgg tgtgattgtt
    14221 gctttcggac gtccttctct gaaattagga ttattctttc ttgcaaacat ttttccttct
    14281 tgggtacgtt ccacaatcat atcacgttcc atttctgcta cactcaacaa cgtccgtgtc
    14341 accattcgcc ccatggacgt attttcaatc gttcctagat tcaaaacctt gatcgttacg
    14401 ttatcatcga gtaaaggttc aatgatctct aatgcttctc tcgtgttacg agcaaatcga
    14461 tcaagcttcg taacaactat ttcatctcca ggcttcagac cagccaacag ctgattgaat
    14521 tttggccgat cccgttttgt acccgtaaat ttttctgaaa aaatattctt cttctctacg
    14581 ccgttctcaa gcaactgttg aatttgttct tttgtacttt gagaagcggt tgagacacgt
    14641 gcatatccat atttcgtcat ttggtccacc tacttttaca aatcatctat cgtatactca
    14701 gaataccctt catagaaata gctgacatcg attcctttca tatataactc gcgatcgtca
    14761 attttatcag tcagagcatt ggaaattaga tagcgtattt ccaaatcgtt tatgggactt
    14821 cgctccattg cagaaagata gtctgcttta tcgattaagt tccaatctac aactttttgc
    14881 aattcttcct ttaaaatgag atccagccaa attctagtac ttcggccatt tccttctcga
    14941 aatgggtgag cgatattcat ctccacatat ttcttgataa tctcttcaaa agaagtttgt
    15001 ggcatctgat caatatgctg taacgaatgt tctaaataca taactggtgc aaatcgaaaa
    15061 tttccttttg caatattgac cgatcggatt tttccggcaa aatcgtaaat atccgaaaat
    15121 agaaattcat gaatttcaga taaaccttta aatgtaccaa cttcgatttc atttattttt
    15181 ccacaatcgt acaattcttt cgctttttgt ttactgagtt tttcttcaac cttagccaac
    15241 tcaacttgat tggttaatcc caatttattc tctaaaatca tgcgaaatct ccttaacttt
    15301 atgacataag tttatgaaac actctcaacc ccattatatc gcgattttgt ttatgtgtca
    15361 aaaactatta agtttctgac ccccgataga tttttcaagt gtctctattt tgcacagtct
    15421 agttggttct gttgcaaagt tttaaataaa gaataaaatc ccttacggta tctatgattt
    15481 aagctgggat tcccaataat accttgattt cagtacagac cgaaaacccg aagagagtgc
    15541 cttcttttcg ggttttctta tataatcctc gaatggcttc catgccttta atcgtggtag
    15601 aggcagtgcg taaacttcga tagaatttat tgcgtctctt tactggacga tggtcttgtt
    15661 caatcaaatt attcaggtat ttaatggtac gatgttctgt cccttgataa aagccgtatt
    15721 cttttagttt cttaaaggca cttgtaatag agggggcttt atctgtgact acaaccttcg
    15781 gttcatcaaa ctgcttcact aaccgcttaa gaaaagcata ggctgcttgt gtgtcccgtt
    15841 ttttacgtaa ccaaatatcc aaggttaaac catctgcatc gatggctcga tacaaataat
    15901 gccattttcc tttaattttg atgtacgttt catccatttt ccatgaataa aaggattttt
    15961 tatttttctt tttccaaatt tgatagagta gtttgccata ttcttgcacc caacgataaa
    16021 tcgtcgtatg agaaacgtta atgccacgat catataagat ttcttgaact tcacgatagc
    16081 taaggttata acgaagatag tagcccacgg ctacaataat cacatcctgc tgaaattgct
    16141 ttcctttaaa atgattcatc gtcattcctc ctgctatctt tttctattat tctaccttat
    16201 ttgatagtag atttaaaact ttgcaacaga acccttttaa tgatattttc caagtcaaac
    16261 ttaatattaa caattcaaaa ctattggaac cactgcaaaa tattttgtta agcagtatat
    16321 atttcaaaaa ttatacgtaa tatatttgta gaaaggttgt ggacagttgt cctattgacc
    16381 tgaaaagtaa tataatagct ggatgaataa agaatccctt atgaacttgt aaatcgttat
    16441 taaatcgctg aattttgata gccattctga agagttatct tcaactacta cactaacttc
    16501 cattaatttc tcattaattt ccctttcgtt caaaaaatat ggttggcttt acaagcattc
    16561 tatcatatga tagaattaag ataacattca aaaggagata ataaaaatgc ggcaaggtat
    16621 tcttaaataa actgtcaatt agatagcggg aataattaat taagcatcct tatttaaaat
    16681 aaggactggt tttttgtgcc cagtttaaga atacttttat cattttatca taaagcatct
    16741 gtggctatca gtgtgtagta tacagctatt tttgtattaa aatcccagtg ataagagtat
    16801 ttatcactgg gattttttct gctttttgag cttttgaatg gaggaaataa aattgaaaat
    16861 tattaatatc ggtatcttag cacatgttga tgcaggaaaa actactttga cagaaagctt
    16921 actatacagt agcggagcaa ttaaagagtt aggaagtgta gatagcggta caacgaaaac
    16981 ggatactatg tttttggaac gccagagagg tattactatt cagaccgcaa taacatcttt
    17041 tcaacgggaa aatgttaaag taaatattgt agatactcct ggacacatgg attttttggc
    17101 agatgtatac cgttcattat ctgttttgga tggagctatt ttgctaatct ctgcaaaaga
    17161 tggagtacag tcacaaactc gtatactatt ccatgcactt agaaagatga acatacctat
    17221 aatatttttt attaacaaaa ttgatcaaaa tggaataaat ttgccagatg tttatcaaga
    17281 tattaaggac aaactttctg acgacatcat aattaagcag actgtgaatc taaatttgaa
    17341 accttatgta atagattata ctgaaccaga acaatgggag acagtaattg tgggaaatga
    17401 ttatttatta gaaaaatata ccattgggaa aacattgaat attgcagaac ttgaaaagga
    17461 ggaaaacgaa agaattcaaa gttgctcctt atatcctgtt tatcacggaa gtgcaaagaa
    17521 taatattgga attaaacaac ttatagaggt aattactagc aaattatttt cacccacaca
    17581 actcaattca gataaacttt gtggaaatgt ttttaaagta gaatattcag atgatggtca
    17641 acggcttgtc tatgtacgtc tttatagtgg aacgctacat ttgcgagact cagtcaatat
    17701 atcagaaaag gaaaaaataa aagttacaga aatgtatact tcaataaatg gagaattacg
    17761 ccagatagat aaggcagagc ctggtgagat tattatttta aaaaatgagc ttttaaaact
    17821 aaataacgta cttggagata aaaaaagatt accacataga gaaattcttg agaatcctct
    17881 tcctatgtta caaacaacaa ttgaaccatg taaatcagta caaagagaaa agttactaga
    17941 tgcacttttt gaaatatccg atagtgatcc ccttctacaa tattatgtag atacagtaac
    18001 tcacgaaatt gtgctatctt ttttaggtga ggtccaaatg gaggtaactt gtactctgat
    18061 tcaagaaaaa tatcatattg agatagaaac aagaaaacca actgtcattt atatggaaag
    18121 accattaaaa aaatctgaat ttaccattga tatcgaagta cctccaaatc ctttctgggc
    18181 ttctattggt ttatctgtaa caccacttcc tttgggtagt ggcattcagt atgagagcct
    18241 ggtttctcta ggttatttaa atcaatcatt tcaaaatgca gttatggaag gtatacgcta
    18301 tgggtgtgaa caaggattgt acggttggaa attaacagac tgtaagatct gttttaagta
    18361 tggtctatat tacagccctg tcagtacgcc agcagatttc cgaatgcttg cgcctattgt
    18421 actagagcag gcttttagaa agagtggtac agagttatta gagccatatc ttagcttcga
    18481 aatttatgta ccacaagaat atctttcgag agcatataat gatgcttcca aatattgtgc
    18541 aaatatttta aatactaagt taaaaggtaa cgaggtcatt ctcattggtg aaattccagc
    18601 ccgttgtatt caagagtatc gaaacagttt aactttcttt acaaatggac gcagtgtctg
    18661 tttaacagag ttaaaaggtt atcaggttac taacattaag tctgctttcc aaccacgtcg
    18721 tccaaataat agaatagaca aagtaaggca tatgtttaat aaaatcaact tacattgata
    18781 gtgaactaaa gagaaatttt taaaatgaat attgagttgt taattagaac aggaggatat
    18841 agatattgta aatactaggt ggatactgtg ccctatatgt ggcaataaga cccgtttaaa
    18901 aatgagggaa gatactgaat taaaaaattt ccctctattt tgtcctaaat gcagacaaga
    18961 aattttaatt gaaataacga agtttagaat aactgtaatt acagagccag acgcaaagac
    19021 gcagagccga taattcgaga tatcaaaatc tcattttatc ggctttttct tttctatgca
    19081 taccattgag cttagttctt gatatccttt ataagaaaat aagtgtactg attttttttg
    19141 cagtagctgt attacagtag acatccctca agcataaaaa gtatacaatt aaaattcaat
    19201 acttgattat tgatgaagta cagagttact cgtcatttca aaactagtat atcagtcaag
    19261 tttttcctaa ggaacaaaaa cgaacttcgc tatgggaatc aaaaattttt agtcggatga
    19321 agtgatatgc aataaatcca gaaaattttc ccaacaacaa aaaatgaact gtactttgca
    19381 gcgataagag taaccaaaga actatttatc attcgctcta gttcctaagt gtaacaaaga
    19441 taaattcatt ttctatttat gattaacaaa aatcagaaaa aattcattac atctttgtaa
    19501 tcaatctttc ctgatagtat taattaatcc attgtgtatt attgaactag ttaaatttac
    19561 atttttctcc gtaaattgct tgaatcactt tcccaatcgt cactaattca tcttcatcca
    19621 gacaatccaa ctgtgcttct acttgaagac gtttggagct tttatgactg ttttcttccc
    19681 ctaaaataaa tccatccaaa gaaatattta gcaaagtcac taaatcatat acaacatgaa
    19741 aacttggctg ttgtccttta ttttcaatgt tcgtcaaata gcgtggcgca atctggatca
    19801 ttgatcctac ctgctcacga gtcaatcctt tactaagacg ggcttcttta atcgcaagac
    19861 ccaatggttt gaaatcaaaa tttgatagag tagtttgcca tattcttgca cccaacgata
    19921 aatcgtcgta tgagaaacgt taatgccacg atcatataag atttcttgaa cttcacgata
    19981 gctaaggtta taacgaagat agtagcccac ggctacaata atcacatcct gctgaaattg
    20041 ctttccttta aaatgattca tcgtcattcc tcctgctatc tttttctatt attctacctt
    20101 atttgatagt agatttaaaa ctttgcaaca gaacccttta aagactatta aatcaatgtt
    20161 aggaaagact attagtaaaa ctatgaatta ttcaggaaaa aaggttcttt tttaaagttt
    20221 tctattgctt cctggcgttg ataaatgaga tataaagtcg gtgtttgtac acgtcctaat
    20281 gaaaatgtac cttgtacgcc tttttgttgt aaattcaagg tatataaagg gcttgcgttc
    20341 atgccgatca accaatcggc aatttggcgt gtttgcgctt cttgataaag gggtacatgg
    20401 aacatagaaa cgaaatagtg cggtagcaca aaagtaaaaa cacaagaaac gttgatttaa
    20461 cgctgttctc gtgtttttct ctttttctat tcgaagtgat tcgctggaac agtcatacga
    20521 aatagtgcgg tagcatgcaa aacccgaaca ttgctagaat tcttctacat tcaatggacg
    20581 taacttaccg ttggataatt cagcttcgta tctaaacgta tacttaccaa caaaattgat
    20641 gtgatcacta attagtggag attgcctgcg tatcatttct tcggaacagt cgaatccttc
    20701 agctttcatt tgttcaaata ctttttctaa atacagtgag ttccaatata tgatggcatt
    20761 agtaactaat cctaatgcat tgagctgctc ttccatccca tcataataag tctggtagag
    20821 ttttcctttt cgtccataaa aaatattacg gcataaggca tgccgagctt cccccttatt
    20881 caattgttct aaaatttgcc gtgcatatat ttcgtcagaa atataacgaa gctgatgttt
    20941 cgtcttataa acttttccat actcagttat tgcttttcct aaaggcgtgg gttgcccatt
    21001 ccgttgaaga gatttcgtta attctgttgc attcactttt ccagatttca acgaacctgc
    21061 aaccctaaga atgtcctccc aatgggtata aatcagttcc atattaattg aattttgaga
    21121 caacgtatca agttccccgt agtgagcgtt agcgtcgatt cgccaaagtt tggttccttt
    21181 atcattggca attcttggac taaattgaaa ccctaataag ccaaagagac caaaaatcat
    21241 atcgctataa ccagctgtat cagtcatgat ctgattagga gttaattcgc tgggttgatt
    21301 gaggaatcct tctagaaggt aaagcgaatc tcgcagtgtc cctgaaacga ccattccgtg
    21361 gaaccctata tattgatcag agacaaaatt gtagaatgtg atcccacgac cacggccaaa
    21421 atattttgga ttacttctag aatataggga acgttgtggt gtgatataac gaataccgtc
    21481 agctgaagcc atatgcccat caccccatat cttagaggtg gcaagtttcc tgtgtgcatg
    21541 tattattttt tgattagctc ctgaaagtgt atccactcga atataatgat gattgacata
    21601 gacaagacga tcatacttta aagaatcaaa tccttctttt gaaaccgggg aaaaaccaat
    21661 attgcaggac tctgataaaa gaactgctaa taaactaata tccaagtctt tcattttggt
    21721 gtccttgtca cttaagtggt taaatgattg agtaagattt aactgttggt ttacttccaa
    21781 taacaaatct gacaaatcaa ttttaggaag taactgctga atgcgacgtc taaaagactt
    21841 atcttccttt ttttcatatg tctttttaag tctagagaca accaggcgat ctgcattttc
    21901 tattctggcc attttagaag taggccaacg atttagcgct tctttataag acagttccaa
    21961 atcgttcttt aaccataaag acatttcatt tgctgaagaa ggaagatcta gttgttctaa
    22021 taaaacgtat ttttgttgaa cccaagtttt ctcatcaatc aagcaatcca taggattgtt
    22081 atataagaca ctctgaggaa tataaatatc atggcgtttt aaagattgaa ttaacaattc
    22141 gacagctgca atcaatacac atttattagt ttgttcaggg tattcatgaa tgtaataaat
    22201 ccatttcttt ggaagagtat gtttaatagc tccaaacatt ttgtaagtaa tcggcttagg
    22261 aaatctatta ttaatgaagg tccagagttc cttacagttg ttaccgtagt cattgctgtc
    22321 aaatgttagt gtagttaaaa tatccggaat aaattttctg aactttcgat aagtgttcag
    22381 aagttcagaa atggctattg gttcacgatc atttttaacc aatagccgaa cttgcgatac
    22441 agcttcggta acattttcct cagaatattt ttctaagata cgatcgcgaa gggatagttc
    22501 attagtatca gaatgactgg acattactaa atctacaata tctgaaagtg tcgatgcggc
    22561 tcgatctaga tcttttatgg tacgaagacg ttctttagat tccttatttt tggcgcgtct
    22621 aaaaacagtt tcaaaaaaat tagatagtgc taaaatttgt tcatccatag ccttacgttt
    22681 gtatatgaaa ataaatgcca ctaacaacgc cagttttttc tgttcactca ttcgttgaat
    22741 taattgagct ttagctttaa atgcataatt tgcaagaact tttattttcc cttcaggaat
    22801 agattccatc ttccattttt cagtagagaa agcttgaaat tgctttagtc ggtcaaaacc
    22861 tctggctatt tctttatgac tatcgtcagc taacggggtt ctcaaaatgt ccattttgat
    22921 tattgcccca taaactggag ttccaattaa ttctaaatga ttgagaagcc gctttctctc
    22981 atcttcagtt ggaaccaaag acaattgtcg gtataaatgc tcttcagctt tttcaattgc
    23041 actagcaaca aaacgagaaa aagtagtaat tccaggtaaa acaatctttt catccagaca
    23101 tttttttaga agcatatcaa acaacatatc tgaagattct gttgtataca gcgctctatt
    23161 taaaagccag ttagctaggt atgtttctat ttccggttgg ttgaaatctt gatatccata
    23221 atgtgatttt atcaattttg tgtgctgata cctggtctgt ctcctgctat agtagataat
    23281 ttctccagga tcaatattta gttgagttgc tacataactc aatacatttt ggggaatatt
    23341 ggtaagatct aatataaaag ttcctaaaaa acgtagtgag actaactgta gtgcaaaacc
    23401 taatctagta gctggtcgtc gtatagtctc catcaattct aaatcttttt catgcaaata
    23461 aaaaaattgg tttaattgtt ctgtactagg ttctcctaaa taaatgccaa atgctttttt
    23521 gttacttttg atttcatcca tttaaaccct ccatgaagta aattttaagt ctacataaaa
    23581 tttattttta aaaatgctat gatagcagta aaactacaag taaattttac atgtaaatta
    23641 tatcactttt aaaaaggagt tttttatggg aaaaattggc tatattcgag tatcttcaca
    23701 agatcaaaat ttggatcgac aattggcaat gatggaagga cttaacattg ataaattatt
    23761 ccaagaaaaa gccagtggta aagatactga gcgtcctgag tttcaaaaat tactaaatta
    23821 tatccgtgaa ggtgattgcg tcatcgttac atcactagat cgtttaggaa gagattatga
    23881 agatataaaa aatacagttg cttttatgaa acagaaaaaa gtagcgttaa aaatattaga
    23941 tgcacagttt ttagatttta atactggaaa tgaactcctg gataccgcta tgttcgatat
    24001 gtttttatca ctgctaagtt atattgcaca aaacgagcgt gagaaaattc gtgaacgtca
    24061 gcggcaagga gtattattgg ctcaaaaagc cggccgatat aagggacgac caatcgagta
    24121 ttctattaac tcaacagatc cgcaaaaacg cttagttttt aaaaccgtgg tggacatgtt
    24181 aaagcaaggc attccagttg cagagattgc aaaagaaaac gggatctctc gaccaactat
    24241 ttataaaata aagaaagcga atgatttgta gaaatatact acattcattc gcttttctac
    24301 cgcactattt cgtttctatg ttccatgtac cccgtatcgg cgatggcatt taggacagta
    24361 aaagtaattt ttttgataaa cactttttgc taattcccca cagtcacact ccacgtgaaa
    24421 agcaatattt cgattaaaac tagttatttc aatgccccaa cgatcataag attttcgctt
    24481 cataaaaatt ttcctccttg taaattttac taacgattat aaataccgtt gccattcttt
    24541 caactgttga ctaattaacg cataaaattc gacttctgat aaaatggtaa tctcatgacc
    24601 taacgcaatc aagtcccgcg cggtttgttc cttttttgta tagagagaat catcaaacaa
    24661 cgacttagaa tactgaccac aaaccaggaa atttgttttt gaagtaacac ttgattgaca
    24721 atggccgttt aaagagtgaa ccaaaccgat ggcttgggtt cgtgtcattt gctgcagcgt
    24781 tccagtaaaa acgacccttt gattcgttaa gtccattttc aaactctccc ttcccgtcta
    24841 atagctgtta tatctatcaa gaaaagtggt gcaaggtatg ttcatattct ttcacccgtc
    24901 gataaaaggt atttcgtttc atgcccaatt gatccatagc atagactgca gttatctttc
    24961 ctgctttcca gtcagaatag atcgcaggaa attcaggagg taaagcaatt ttctttctgc
    25021 cgaattttac acccttttgt ttcgcagctt ctacgccttc tctttgccgg ctattaattc
    25081 gtttccgctc gtcttcggcc atatagctga gtaattgcag aattaagtca gagataagcg
    25141 tctctaaccc atctagttgc ttgtaactag cagtatctaa cagaggcatg tctaacacag
    25201 aaatatcaat ctgcttttcc ttagttaatt ctcgccattc ttctaaaatc atttgtttat
    25261 ttctgcctag tctatctaat gattgtagat agagtaaatc tccttttcga aacatccgtt
    25321 tcattaattg atattcaggg cgtttaaaat ctttgccgct ggctttttct acaaatatat
    25381 attcttcagg gattcctaat tccttcgcgg aaatcagttg tcgttcgatc gattgatcat
    25441 aactactgac ccggatataa aaaaattttc tcatcgtttt tatctaccct tttttcacta
    25501 aaattgtttc aaaacaatca gattaaatca gaaacgtttc aaattgtatt atgtggttat
    25561 tatgccatac ataaacaaag aaaatcaagg catgtcaaaa agtatacttt ttgaaacagt
    25621 aagtttacac tcccgcatga ttatatttat tccgctaaaa tacataaaaa tggcaggcct
    25681 taacggtctg ccattaaata aactagttat ccagtttttc ttttatgtct tccatggtat
    25741 attttatttt tcacatcaga atttgacttc tttaactttt acaatttttt taacactatt
    25801 attctattac aacactatat atttctaatt tagggttaaa aataaatctt tttgatactt
    25861 ttgcctttac aatataattg tattctttct ttttttcttt gaagtcgctt gattcaactg
    25921 taacttcaaa ccacatttca tttggagact cttttaattt ttttacttga aatgaattat
    25981 ctcttggatc ataaggtggt actctttcaa actcaggaag ttttctctgt atttgttctt
    26041 caggagtatt cgcaaagtaa tctactatct tgacagttat taaaagtact actattccca
    26101 aaactataac aaacataaag ataattccac atccagaatt atttttatta ttttgagtca
    26161 gattattcca ttctatttct tccataatca tcatgtcctt ttacaattca tatacttatt
    26221 ttatcgtata tatttaaaaa ggaaaaggac actgtttaaa tagtaaacga ttcttaatta
    26281 agtttacttc tattttcttg aaattgaata attttttcag aaaatccatt tgcaactttc
    26341 ccctcatctc caataaaatc aagataagta aaatctgtcc caagtgaatt attaactatt
    26401 ttatcaatga aaaatgaaat tatccctaca cctaagatat caactgtttc gtcattttct
    26461 aataaactat ttgttactga agcgatttta tctgaagaac caaatctgtt cttaacaaat
    26521 tgattaaatc tatcaatagc acccttatca caatagtacg tttttaaagc cgataaagct
    26581 g
//
