LOCUS       NZ_CP059819            24162 bp    DNA     circular CON 20-SEP-2023
DEFINITION  Enterococcus faecium strain BP657 plasmid pBP657_P3, complete
            sequence.
ACCESSION   NZ_CP059819
VERSION     NZ_CP059819.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14675395
            Assembly: GCF_012933075.2
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24162)
  AUTHORS   Veeraraghavan,B., Vasudevan,K., Arumugam,A., Solaimalai,D. and
            Bakthavatchalam,Y.D.
  TITLE     Complete genome of vancomycin resistant Enterococcus faecium
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24162)
  AUTHORS   Veeraraghavan,B., Vasudevan,K., Arumugam,A., Solaimalai,D. and
            Bakthavatchalam,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2020) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore, Tamil Nadu 632004, India
REFERENCE   3  (bases 1 to 24162)
  AUTHORS   Veeraraghavan,B., Solaimalai,D., Vasudevan,K. and Arumugam,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-APR-2020) Department of Clinical Microbiology,
            Christian Medical College and Hospital, Ida Scudder Road, Vellore,
            Tamil Nadu 632004, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method :: CANU v. v. 1.7; UNICYCLER HYBRID v. v. 0.4.6
            Assembly Name                     :: BP657
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 44.03x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/20/2023 06:25:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,092
            CDSs (total)                      :: 2,999
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 38 of 116
            Pseudo Genes (incomplete)         :: 72 of 116
            Pseudo Genes (internal stop)      :: 30 of 116
            Pseudo Genes (multiple problems)  :: 20 of 116
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059819.1.
            Bacteria and source DNA available from Christian Medical College.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="BP657"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pBP657_P3"
                     /geo_loc_name="India: Vellore"
                     /lat_lon="12.9165 N 79.1325 E"
                     /collection_date="2017"
                     /collected_by="CMC Vellore"
     gene            join(23853..24162,1..371)
                     /locus_tag="HI829_RS15000"
                     /old_locus_tag="HI829_015000"
     CDS             join(23853..24162,1..371)
                     /locus_tag="HI829_RS15000"
                     /old_locus_tag="HI829_015000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            569..1174
                     /locus_tag="HI829_RS15005"
                     /old_locus_tag="HI829_015005"
     CDS             569..1174
                     /locus_tag="HI829_RS15005"
                     /old_locus_tag="HI829_015005"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            1190..1762
                     /locus_tag="HI829_RS15010"
                     /old_locus_tag="HI829_015010"
     CDS             1190..1762
                     /locus_tag="HI829_RS15010"
                     /old_locus_tag="HI829_015010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002303206.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENCVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(2235..2807)
                     /locus_tag="HI829_RS15015"
                     /old_locus_tag="HI829_015015"
     CDS             complement(2235..2807)
                     /locus_tag="HI829_RS15015"
                     /old_locus_tag="HI829_015015"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_073120187.1"
                     /translation="MCQKNCCHSIISKENLLNQDFSTETICEKWAADITYIPTKKNGWC
                     YLSSIMDLHTKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREV
                     EQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGF
                     YNRNRIHSSIHYLTPQEFEELAKEKMA"
                     /name="IS3 family transposase"
     gene            complement(2908..4070)
                     /locus_tag="HI829_RS15020"
                     /old_locus_tag="HI829_015020"
     CDS             complement(join(2908..3794,3794..4070))
                     /locus_tag="HI829_RS15020"
                     /old_locus_tag="HI829_015020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_127817621.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKWV
                     KQSKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANKHL
                     YPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSKRGI
                     QISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIVTDLT
                     YVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFHTDRGK
                     EFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLEL
                     FDYVNWWNHLRLHGTLGYETPVGYRNKRLAQRILDNELGCANASEAV"
                     /name="IS3 family transposase"
     gene            complement(4476..4730)
                     /locus_tag="HI829_RS15030"
                     /old_locus_tag="HI829_015030"
     CDS             complement(4476..4730)
                     /locus_tag="HI829_RS15030"
                     /old_locus_tag="HI829_015030"
                     /inference="COORDINATES: protein motif:HMM:NF013677.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000199136.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYLP
                     DQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
                     /name="transposase"
     gene            complement(4923..5198)
                     /gene="prgO"
                     /locus_tag="HI829_RS15035"
                     /old_locus_tag="HI829_015035"
     CDS             complement(4923..5198)
                     /gene="prgO"
                     /locus_tag="HI829_RS15035"
                     /old_locus_tag="HI829_015035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            complement(5170..6123)
                     /locus_tag="HI829_RS15040"
                     /old_locus_tag="HI829_015040"
     CDS             complement(5170..6123)
                     /locus_tag="HI829_RS15040"
                     /old_locus_tag="HI829_015040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            6735..8228
                     /locus_tag="HI829_RS15045"
                     /old_locus_tag="HI829_015045"
     CDS             6735..8228
                     /locus_tag="HI829_RS15045"
                     /old_locus_tag="HI829_015045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            8363..8659
                     /locus_tag="HI829_RS15050"
                     /old_locus_tag="HI829_015050"
     CDS             8363..8659
                     /locus_tag="HI829_RS15050"
                     /old_locus_tag="HI829_015050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(8683..9642)
                     /locus_tag="HI829_RS15055"
                     /old_locus_tag="HI829_015055"
     CDS             complement(8683..9642)
                     /locus_tag="HI829_RS15055"
                     /old_locus_tag="HI829_015055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_002287225.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLFF
                     KQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIRCS
                     ARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFKSITF
                     DCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDESF
                     IQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
                     /name="IS30 family transposase"
     gene            complement(9914..10594)
                     /locus_tag="HI829_RS15060"
                     /old_locus_tag="HI829_015060"
     CDS             complement(9914..10594)
                     /locus_tag="HI829_RS15060"
                     /old_locus_tag="HI829_015060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<10669..>11301)
                     /locus_tag="HI829_RS15065"
                     /old_locus_tag="HI829_015065"
                     /pseudo=""
     CDS             complement(<10669..>11301)
                     /locus_tag="HI829_RS15065"
                     /old_locus_tag="HI829_015065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein"
                     /name="tetracycline resistance ribosomal protection
                     protein"
     gene            11377..12057
                     /locus_tag="HI829_RS15070"
                     /old_locus_tag="HI829_015070"
     CDS             11377..12057
                     /locus_tag="HI829_RS15070"
                     /old_locus_tag="HI829_015070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <12114..12614
                     /locus_tag="HI829_RS15075"
                     /old_locus_tag="HI829_015075"
                     /pseudo=""
     CDS             <12114..12614
                     /locus_tag="HI829_RS15075"
                     /old_locus_tag="HI829_015075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /name="IS6-like element IS1216 family transposase"
     gene            <12670..12927
                     /locus_tag="HI829_RS15080"
                     /old_locus_tag="HI829_015080"
                     /pseudo=""
     CDS             <12670..12927
                     /locus_tag="HI829_RS15080"
                     /old_locus_tag="HI829_015080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParA"
                     /name="chromosome partitioning protein ParA"
     gene            13019..13234
                     /locus_tag="HI829_RS15085"
                     /old_locus_tag="HI829_015085"
     CDS             13019..13234
                     /locus_tag="HI829_RS15085"
                     /old_locus_tag="HI829_015085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="WP_001835296.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETA
                     KNGGNVKEVMDQALEEYIRKYLPDKL"
                     /name="peptide-binding protein"
     gene            13251..13523
                     /locus_tag="HI829_RS15090"
                     /old_locus_tag="HI829_015090"
     CDS             13251..13523
                     /locus_tag="HI829_RS15090"
                     /old_locus_tag="HI829_015090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="WP_000301765.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEVN
                     LLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
                     /name="antitoxin"
     gene            13525..14388
                     /locus_tag="HI829_RS15095"
                     /old_locus_tag="HI829_015095"
     CDS             13525..14388
                     /locus_tag="HI829_RS15095"
                     /old_locus_tag="HI829_015095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016301 - kinase activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="WP_001284311.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGSG
                     KTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAIIS
                     RLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYETMY
                     ADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETPSISP
                     KETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQPPTPPIPKT
                     PKLPGI"
                     /name="zeta toxin family protein"
     gene            complement(14651..15388)
                     /gene="erm(B)"
                     /locus_tag="HI829_RS15100"
                     /old_locus_tag="HI829_015100"
     ARG             complement(14655..15388)
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="99.59"
                     /coverage="100.0"
     gene            complement(15513..15596)
                     /locus_tag="HI829_RS15105"
                     /old_locus_tag="HI829_015105"
     CDS             complement(15513..15596)
                     /locus_tag="HI829_RS15105"
                     /old_locus_tag="HI829_015105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="WP_031929417.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuator leader peptide
                     ErmL"
     gene            complement(15645..>15728)
                     /locus_tag="HI829_RS15680"
                     /old_locus_tag="HI829_015110"
                     /pseudo=""
     CDS             complement(15645..>15728)
                     /locus_tag="HI829_RS15680"
                     /old_locus_tag="HI829_015110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502600.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MLS leader peptide"
                     /name="MLS leader peptide"
     gene            complement(15885..16844)
                     /locus_tag="HI829_RS15115"
                     /old_locus_tag="HI829_015115"
     CDS             complement(15885..16844)
                     /locus_tag="HI829_RS15115"
                     /old_locus_tag="HI829_015115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_002303350.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRFL
                     KSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIACS
                     VRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEFGHL
                     EGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFKSITF
                     DCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNGVSETF
                     IQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
                     /name="IS30 family transposase"
     gene            complement(17204..17998)
                     /gene="aph(3')-IIIa"
                     /locus_tag="HI829_RS15120"
                     /old_locus_tag="HI829_015120"
     ARG             complement(17208..17998)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(18091..>18342)
                     /locus_tag="HI829_RS15125"
                     /old_locus_tag="HI829_015125"
                     /pseudo=""
     CDS             complement(18091..>18342)
                     /locus_tag="HI829_RS15125"
                     /old_locus_tag="HI829_015125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /name="GNAT family N-acetyltransferase"
     gene            18587..19882
                     /locus_tag="HI829_RS15130"
                     /old_locus_tag="HI829_015130"
     CDS             18587..19882
                     /locus_tag="HI829_RS15130"
                     /old_locus_tag="HI829_015130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="WP_002297218.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRAC
                     RSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQSY
                     FVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSKKIL
                     PRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEEVEFL
                     VTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKSQAEKL
                     KKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAYPFFHEL
                     VEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
                     /name="ISL3-like element ISEfa11 family transposase"
     gene            complement(19942..20628)
                     /locus_tag="HI829_RS15135"
                     /old_locus_tag="HI829_015135"
     CDS             complement(19942..20628)
                     /locus_tag="HI829_RS15135"
                     /old_locus_tag="HI829_015135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_059355960.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLW
                     LFVNKD"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(20682..20900)
                     /locus_tag="HI829_RS15140"
                     /old_locus_tag="HI829_015140"
     CDS             complement(20682..20900)
                     /locus_tag="HI829_RS15140"
                     /old_locus_tag="HI829_015140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002347151.1"
                     /translation="MNNKNTKNTNTNHEKRSFFDKLFKKKKNGKVSILKMIGWIFLAFF
                     IVAVNSSGGDKKEAASKDTTKGSVAKF"
                     /name="hypothetical protein"
     gene            complement(20948..21220)
                     /locus_tag="HI829_RS15145"
                     /old_locus_tag="HI829_015145"
     CDS             complement(20948..21220)
                     /locus_tag="HI829_RS15145"
                     /old_locus_tag="HI829_015145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002303415.1"
                     /translation="MLGSFKKDKEVKTRGALTPSQQNKLGTKATFHPVRDQANQKELIG
                     VCVGFTSEKFFPIIECKIHGITTREVARKVVKWHTSQTKTNHKKR"
                     /name="hypothetical protein"
     gene            complement(21210..21419)
                     /locus_tag="HI829_RS15150"
                     /old_locus_tag="HI829_015150"
     CDS             complement(21210..21419)
                     /locus_tag="HI829_RS15150"
                     /old_locus_tag="HI829_015150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002303414.1"
                     /translation="MIRKLNNIKLSLAILTLFFGIYNNSRMALFFLTLLIFMNLIIHNF
                     KELENTAPAPSQGNQESEGMPHAW"
                     /name="hypothetical protein"
     gene            complement(21550..21828)
                     /locus_tag="HI829_RS15155"
                     /old_locus_tag="HI829_015155"
     CDS             complement(21550..21828)
                     /locus_tag="HI829_RS15155"
                     /old_locus_tag="HI829_015155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002303413.1"
                     /translation="MEKKEDLLNAFKNLDEKDQLKALLRLHDITYSDIAERLTVKKGER
                     EGQKGVSLVTVQKAFQSKTNLESDRWKEIVKVATKLIEERQNDQNKA"
                     /name="hypothetical protein"
     gene            complement(22133..22441)
                     /locus_tag="HI829_RS15160"
                     /old_locus_tag="HI829_015160"
     CDS             complement(22133..22441)
                     /locus_tag="HI829_RS15160"
                     /old_locus_tag="HI829_015160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002303412.1"
                     /translation="MKEMKMKQVIYPVIIGVLAIALIILGVNCYNLSKENNQLETKNNK
                     QEIQIAKQAYVISDYKTYFRENYVDTVKYRSHFTDKQILNVYREALRDGKISDEGAN"
                     /name="hypothetical protein"
     gene            complement(22615..22983)
                     /locus_tag="HI829_RS15165"
                     /old_locus_tag="HI829_015165"
     CDS             complement(22615..22983)
                     /locus_tag="HI829_RS15165"
                     /old_locus_tag="HI829_015165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002347150.1"
                     /translation="MENTNQTPNTAPTNQTSPAERKADLIRLYSRLEGMKLQHVPTAPK
                     APDGFPKSAESLEFFECKVCGSTFQTILRESVASGCPKCEHDRLGILADHLPEPDKNSC
                     LNNRKKPVTVMAMGFLCI"
                     /name="hypothetical protein"
     gene            complement(23097..23714)
                     /locus_tag="HI829_RS15170"
                     /old_locus_tag="HI829_015170"
     CDS             complement(23097..23714)
                     /locus_tag="HI829_RS15170"
                     /old_locus_tag="HI829_015170"
                     /inference="COORDINATES: protein motif:HMM:NF013235.3"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_182482101.1"
                     /translation="MELLQTGINLHSIYMVDENENEIITAPAIARWVINKHTLEVTARI
                     NPEYLEWFSEVVNQYILFNLRDFVKLKSKYSMILFLELSTFWNTGMYYKRINDLREILG
                     VNPTRNNRDFINNVLKPAIAALKEYFPELSLTVEKNSSDSRKITHVRLKFDKLTITDMQ
                     ERLRSSEGASLVEYQQELENMEGEEKAVNDPTPEIDLSNVEW"
                     /name="replication initiation protein"
     ARG             complement(10649..11253)
                     /name="tet(M)"
                     /gene="tet(M)"
                     /gene_name="tetracycline-resistant ribosomal protection
                     protein"
                     /tool="rgi"
                     /drug_class="tetracycline antibiotic"
                     /identity="95.02"
                     /coverage="31.46"
     ARG             complement(14652..15388)
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.78"
                     /coverage="98.79"
     Typing          6736..8228
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
       61 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      121 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      181 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      241 gcactgcctc taccacgatt aaaggcatgg aagccattcg aggattatat aagaaaaccc
      301 gaaaagaagg cactctcttc gggttttcgg tctgtactga aatcaaggta ttattgggaa
      361 tcccagctta aatcatagat accgtaaggg attttattct ttatttaaaa ctttgcaaca
      421 gaaccaacta gactgtgcaa aatagagaca cttgaaaaat ctatcggggg tcagaaactt
      481 aatagttttt gacacataaa caaaatcgcg atataatggg gttgagagtg tttcataaac
      541 ttatgtcata aagttaagga gatttcgcat gattttagag aataaattgg gattaaccaa
      601 tcaagttgag ttggctaagg ttgaagaaaa actcagtaaa caaaaagcga aagaattgta
      661 cgattgtgga aaaataaatg aaatcgaagt tggtacattt aaaggtttat ctgaaattca
      721 tgaatttcta ttttcggata tttacgattt tgccggaaaa atccgatcgg tcaatattgc
      781 aaaaggaaat tttcgatttg caccagttat gtatttagaa cattcgttac agcatattga
      841 tcagatgcca caaacttctt ttgaagagat tatcaagaaa tatgtggaga tgaatatcgc
      901 tcacccattt cgagaaggaa atggccgaag tactagaatt tggctggatc tcattttaaa
      961 ggaagaattg caaaaagttg tagattggaa cttaatcgat aaagcagact atctttctgc
     1021 aatggagcga agtcccataa acgatttgga aatacgctat ctaatttcca atgctctgac
     1081 tgataaaatt gacgatcgcg agttatatat gaaaggaatc gatgtcagct atttctatga
     1141 agggtattct gagtatacga tagatgattt gtaaaagtag gtggaccaaa tgacgaaata
     1201 tggatatgca cgtgtctcaa ccgcttctca aagtacaaaa gaacaaattc aacagttgct
     1261 tgagaactgc gtagagaaga agaatatttt ttcagaaaaa tttacgggta caaaacggga
     1321 tcggccaaaa ttcaatcagc tgttggctgg tctgaagcct ggagatgaaa tagttgttac
     1381 gaagcttgat cgatttgctc gtaacacgag agaagcatta gagatcattg aacctttact
     1441 cgatgataac gtaacgatca aggttttgaa tctaggaacg attgaaaata cgtccatggg
     1501 gcgaatggtg acacggacgt tgttgagtgt agcagaaatg gaacgtgata tgattgtgga
     1561 acgtacccaa gaaggaaaaa tgtttgcaag aaagaataat cctaatttca gagaaggacg
     1621 tccgaaagca acaatcacac cgaagaagag gcacgcatat gaactgctta cttcaggtaa
     1681 atcgtataag gaagttgaag ctataaccgg tttcagtcgc agtacgcttt ttagaataaa
     1741 gaagaaaatt gaagaaagtt aaaaaagaag tctcagcgaa ccagacaggt aaatacttaa
     1801 tgcgttctag atatgagtct attagcatgt tgtgaaatat aatatttttt tatttacttg
     1861 atttctgctc aaaaaatgtg tatggtaact gtaaaaggta aagtaattaa aggtatgcta
     1921 gccacgctta ctatattagg ataccatcat atatttataa tgaacgattt gttcgtctac
     1981 caaacaacac atatcgttca gcgtaagtca cgtttaggaa cgtggctttt ttagtgttat
     2041 tatcgataaa taatctattg actctattga ttttatctcc atatccctac ggtgttgatt
     2101 gtctttagat ctttcattta agaaccaaat aactatcata aaaatcagca ctgctgctaa
     2161 tataataaac agcattccta ttgtgatatt actggatttg agtcaatatc ttggacacat
     2221 tttagtagag acggttaagc cattttttct tttgctaatt cttcaaattc ctgtggggtt
     2281 agatagtgaa tcgagctatg gattcgattt cggttataaa atccttcaat gtagctaaat
     2341 agcgctcgat ttgcttcttc aaaatctgag tagctagtcg tgtagacttc ttcttttttc
     2401 aatgaggcat ggaaagattc gattccagca ttatcataag gtgttccttt tctactataa
     2461 gaatgcctta ttttgttggt tttaagccat tgttccactt ctcttgctgt gtattggctg
     2521 cccaagtcag tgtgtagaat cattccttct ggaatgtgat aatgtatttt tgctttattc
     2581 aatgtttgaa tgacacaatc cacagtcatt cgttttgaaa atgtataact aataattctt
     2641 ttcgtgtgta aatccatgat tgaagataag taacaccaac catttttctt agtaggaatg
     2701 tacgtaatgt cagctgccca tttctcacag atcgtttcag tagaaaagtc ctgatttaag
     2761 agattctctt ttgaaatgat ggaatggcaa cagttttttt gacaaatttt ataaggtgca
     2821 gaacttcttt ccgtatgcta ttccgattgt ccttgacaat gagcctcctc ggatgtgacg
     2881 atcttcggca ggagctaaca gttaaagtta gactgcctcg ctagcgttag cacatccgag
     2941 ctcattatca aggattcgct gcgccaatct cttgttacgg taaccaaccg gtgtctcgta
     3001 gccaagtgta ccgtgcaacc gaaggtggtt ccaccaattg acatagtcaa ataactccaa
     3061 atccaattgt tgtaaggttt caaatgtgta ttgatagaca aattctactt tcaacgactt
     3121 ataagttgat tcagctacgg cattatcaaa aggacagcct ttatgactca atgatcgatt
     3181 gatgtcaaaa gttgttaata attcatcaat agcttggtta tcaaactctt ttccacgatc
     3241 agtatgaaaa atctcaacct ctgtcagagg ttgtttgata cggctaaatg ctttttttac
     3301 tagaacggca tctttatgtt ctccacaaga atagccgaga atttctcgat tgaacagatc
     3361 caaaatgaaa cagacataat tccatttttt cccgactcgt acataagtca agtctgttac
     3421 gatcgcttct aatgggttgt ctcttaagaa tttacgattc aatacgtttg tcgttttggc
     3481 ttcattgcaa gtagaatgat gtactttaaa ataagcaaca gtatagctcg attttaatcc
     3541 tctatttttc atgattctac taatttttcg tcggctgatc tgaatgcctc gttttgataa
     3601 ggcttttttt atttttcttg agccgtaggc ctttcggctg cggataaatt cttcagcgac
     3661 tacttcttca agttctgatt cgtctttctt tggttttgat tgataataat aggactgacg
     3721 tgatagacct aatattctgc acatcgctga tatagggtaa agatgcttat tcgcatcgat
     3781 tacttgtctc ttcgtccgaa tatcagcgct gcttgcttta aaatatcatt ttccatttct
     3841 aattgctggt ttcttttacg tagttctaac aattcttttt gttcaggcgt aagattatct
     3901 ttttctttga atgaaccact cgttttagat tgctttaccc atttgtcaaa tgctgaagcc
     3961 gttagttcat attctcgaat gatttctaca cgtggctttc cagctaagta aagattgacg
     4021 atttgttgct tgaattcttg tgaaaaagtt cttcgtgttc tcttagacat aaaaattcct
     4081 cctggtatgt tttcttctag tctacacacc ttaatttttc tgtctagtta attgtagcct
     4141 atccatgatc ggtttattag acctttgagg tctatatttt ttaactacaa tcgaccttaa
     4201 atttaattgt ttcattagct tttggacatg tttaagagat actgaaatcc cttcttttaa
     4261 taaaacttga tggatctttg tggcaccata gcgttgttta ttcgtaaaaa aaattgttga
     4321 aatcttcttt ttcaacttat tatttctgat ttctgtagct gtcaacggtt tattcttata
     4381 aaaataatag acacttctag ggatttctaa taaccgacac aacaaagaaa cagtgtaatc
     4441 cttacaccat ttttcaataa attgaacaag cgaatttagg ttttccgaga gaatatggct
     4501 gcggcttttt ttaagatttc aagttcctca tttaaacgag cattttcttt tctcagttca
     4561 gctacttctt ttccagtcag tcctgtggac tgatcaggta aatataaatt cttccatttg
     4621 taaatcgttg cttcagataa gccatattct ttcgctaacc ctcgaacaga acgtccagtt
     4681 tgattcagtt caacaatcat ttgtttaaaa ttttcttcat atcgggtcat aaaaattcat
     4741 cctctcgtag ataagtttaa tttattcttg tctctacgaa aagctgtcta agatttgata
     4801 ctaacaccaa atgttgtata cccccaaaca atacacatat tttgaaggat taggattaat
     4861 aaagctaaaa atatagtaag tatactaaat atatttacta tatctagtat acttactata
     4921 ttttaatctt ttgatcgtct attatatata atccgttcct cgtcgtttaa agtatcaaca
     4981 taggcgtcca ttgcaagttt gactatttca tacataggaa tatcttttgc ataactaaga
     5041 tcccgaatgg tttttagtac gggaggatct acttgaactg gttttctttc tttcgcagtg
     5101 tactttcgtt cccctaactc gacattaata tcatctttaa ttgaaatatc ttcagcacca
     5161 attttcttct tatctttgtt cgttggtaat aatgccattt agtttaatct cctttccaag
     5221 aggtaggata tgattggcca ttgagtcagc atatttaggt gtataatcaa atccttcaat
     5281 atcaccatgt tgttcatagt attcaattct ttcttctaat tctgtaaaga tgtctgcaaa
     5341 aatagcccac catcttcgat ctacataatc atttaattgg ataccattct caccatacat
     5401 ttctaaccga tccgagcctt taacaatgct tttaaaaatg tttgattcac catacttatc
     5461 aattgttttt tgatagtttg cgtgttgaga ggaacgtcgc actgagaaaa gaacaggcaa
     5521 aattccaatg atttgaagat gagactcttc aaaattcgtg acaatcggaa ctaaaacttt
     5581 attaataaaa tcttctgttc cttccattgc gtaccgtttt aattcttgca ttgcaataat
     5641 ataatctgca gcagttaaga atgcacgaac cacattatct gttgatggtg ggcagtcgat
     5701 aaagatataa tcgaaatttt ttctcaattc ttctaaaggt ttaatgaagg ccaatgatct
     5761 cttacgacga tcaggatatt tttcggacaa gtattcatta agttcttcag atccaggaga
     5821 gccagccata atatataaat gtggacttac ttgagtaata cctgaaaccc agtccccttt
     5881 tttgattgct gcagacatgg atcgatcaaa gctagtaatt tgatacgttg atccaatgtt
     5941 ggaagtagta tttctttgtt ggtcataatc aattagcaac acgtcttttt caaaaagttg
     6001 actagaaaca atcgctaata aatcattgtc tgtagtctta ccaatgccgc cttttctacc
     6061 tgtaagcatt acaacttttc ctagtttatc tgatgtttta aatgcagtcc gtaagttttc
     6121 catagttccc tccaatttcc tatactaaat atatttagta tacttcatat acttaatata
     6181 ttcgatatat ctaatatact ccaaattgat aagaattcag actttataag gaatatagtg
     6241 gatatactaa atatatttgc tatattcagt atatcagata tattcaaaat gtcaaaatat
     6301 atttgtgcgt tttgcgttga caatttagag tgaaaagagg taaacttaat tctatagaaa
     6361 ccacagataa ttcactattt acaaagtagc aaaagcagtg gtactcttta aacagaaaaa
     6421 ttacataaaa aaaagagacg gaaataattg attttagcag aatcaattat ttctgaatca
     6481 catggttagg acatgtgttc acgctcgtct caagaatatg taagtagcta ccaactactt
     6541 atattaaaag ttgatcggat accttttccg attgccttta ttctaccaaa aaaaggcgag
     6601 caactcaaca gaagaacgtt tatttagtgt acttaaatta aatattctta aacactgaag
     6661 agagaacaca tactatggct gagattaaag ctaaactgtg ttctcttttt gtttgagaaa
     6721 ggacgttaca atcgatgttg agcgaaattt attcagctat tcttaaaaac ggcttacgta
     6781 catacaaata tcgaaacagc accatgaaac ctgcaggtca tattgattcc agtaggagtg
     6841 gtgctatctt tgcgtaccgt agcaagcaat taatgaatgt tgggcgtggt atggtcatta
     6901 cttcggaaga agctatttta gagaacgaaa agaaactaac gcattggaca cctaatacct
     6961 atcgctttgg tacttatgcg gatgattatc gaacagtggt taaaggtcat tctgagaaaa
     7021 acttaagtca aatcaacaca tttgtagttg atatcgattc aaaagagaac catcaaggcg
     7081 aaattatttt agcctgttta gatcaagtgg gctacatgcc aacgctaatt ttagaatcag
     7141 atcatggtta tcaagtttat tttgtactaa agacaccagg ctatgtcaca aagaaaagca
     7201 atttcaaggt gatcgatgta gcaaaaaaaa tttcaaaaac aattcgtcta cagttggctg
     7261 aaaaattgtc cggagtggat ctaggatgta accacttcgg aattgctcga ttcccacaag
     7321 aaaataatat tgtttttaaa gaaatgaact atcagtattc ttttgctgac tggattcaat
     7381 ggtcgatgaa gcttgaatca gatcaaaaaa caaaagaaga tcgagaacga aaactaattg
     7441 tctttcctga gaaaaaagaa attcgtcaag tagatgaacc gtggttcgat atgttacttc
     7501 ataaagcaaa catcgtcggc ggagaaggac gtcttggtcg aaataatgtg attttcacgc
     7561 tttctttagc ttattactct tcaggttatg cattggatac ttgcgaatac aatatgttca
     7621 cattcaacga acggttacag gaaccgctat ctgaagcaga attagtaaag attgtacgta
     7681 gtgcttattc tggtaattat caagcagcaa gcagagaatt cattattgaa ttgtgccagc
     7741 aatgggtttc accaacctta aaaaataatg atctgttcat tcaacgacgt ggctggtgga
     7801 aatttaaaaa gccacgagat caaagaaaat atagtcataa aaatgaatgg aaagaagatc
     7861 tattggctta tctaagcgaa aaaagtcttg ctagtgagcc ttatttgaac ctgtcaaaaa
     7921 aagaattggc ttcacaacta acgatgccca agcgaacact tgataagatc ttaaatgagt
     7981 tacgagagga gaataaagtc ttctacaagg taacacgagg aagaaatggc ggaatgatca
     8041 ttgcttcagt caaaacgttg ttcgcgaggg ttattcaact aagtaaagaa aagagactag
     8101 attattcaac aaggatcaca gaggtatttg gactcaacga gagcttagta gaagagacat
     8161 ttagacaatt atcaaccccc ttgaaccctc ttaaagaagt gaatcttttt gaagtagata
     8221 caggttgaaa aataaaaggt gcaaattgcc ttatacaata tatctatgat acttctgtag
     8281 gtgttgctcc ctttgcctag ctacgtgtag gtggtatact tataactgcg tatgcagtct
     8341 tatgtatcat ggaggaagtt gtatgtcgtt aaaaaattat gtctattcac atcctgttaa
     8401 tgtgtttatc attggtcgtt tgggattatc tgtggaagtg ttctgtgagc tttatggttt
     8461 taagcagggg actttgtctt cttgggttac cagggaaaaa acagttgctt ctttgccgat
     8521 tgagtttctt catgggttgt ccttagcttc tggggagact atggatcagg tatatgattg
     8581 tttgtgtgtg ttagagcagg agtatattga gtataaaata gctaacgagt taagaaaaag
     8641 gaagaagtat atccagtagt agtttttatt tactcttaat tgtcaaatta agttagacaa
     8701 atcatcaata cttacgtaac tcaaaaatac ttccaaaggt gttcgataat tcagtgattt
     8761 tctaggaata ttatttcgtt tcgatgcgac agattgaata aaagattcat ctactgaatt
     8821 gaaatccata gatttcaata aaccatctct acgtaacaat ccgttagaat tctcgtttag
     8881 gcctctttga gacggcgttc ctggatcagc gaaataaatg gcaatatcat tggcattact
     8941 gatctgtttc caatttgaaa attcctttcc acaatcaaaa gtgatggatt tgaatagatt
     9001 tttcggtaca gattcaaacc aatgatttaa tttgttttca atatcaatcg cttgtctacc
     9061 acacggtttc aatgtgatga taacttttga taatcgctca actaaggtaa ttacagcact
     9121 tttatgtttc aaacctacga tagtgtcacc ttcaaggtga ccaaactcat ttgagaattg
     9181 gctataatct ttttcacgtt catgaataga gcgacggaaa gcttgttttc cacgtctttc
     9241 ttgatgtcca tttggtttac gcttgccttt catcggtaag tcagaaggat taaatagccc
     9301 ctttttgaac atacgataaa tggtacgagc agaacaacga ataggaaacg ctgcacgacc
     9361 aacaatcaca tcgggtgtcc atccttgaac aacctttctt tgaatatatt ctgattgttc
     9421 ctcaggtaaa acaagcgggc gtctaccaca gtttgatttg tttttcttat actgttgata
     9481 gtactctaag gctgattttc cttgcttgaa gaacaggtat actttatgga tcgtttgtct
     9541 tgaacgattc aagaaatgcg cagttttcgc aacagattga tttattttga aataagactc
     9601 tatcattaca agttcatccg ttgtaagatg ggtataggtc atttgtactc actccttata
     9661 attctttgga cggaactatt ttgagtgtag cacaaatgac ttttttagtt gtctagctta
     9721 attttacaat cggcgtactt aaaaaattgg ttcattgagc aacctatcgc tgctaaagta
     9781 gcaaaggaaa acgttaaagg aaagaattta gggaagaaat cgaaatgaaa tcggacgact
     9841 ggattgaaca cacctggctg gttctgttgc aaagttttaa ataaagaata aaatccctta
     9901 cggtatctat gatttaagct gggattccca ataatacctt gatttcagta cagaccgaaa
     9961 acccgaagag agtgccttct tttcgggttt tcttatataa tcctcgaatg gcttccatgc
    10021 ctttaatcgt ggtagaggca gtgcgtaaac ttcgatagaa tttattgcgt ctctttactg
    10081 gacgatggtc ttgttcaatc aaattattca ggtatttaat ggtacgatgt tctgtccctt
    10141 gataaaagcc gtattctttt agtttcttaa aggcacttgt aatagagggg gctttatctg
    10201 tgactacaac cttcggttca tcaaactgct tcactaaccg cttaagaaaa gcataggctg
    10261 cttgtgtgtc ccgtttttta cgtaaccaaa tatccaaggt taacccatct gcatcgatgg
    10321 ctcgatacaa ataatgccat tttcctttaa ttttgatgta cgtttcatcc attttccatg
    10381 aataaaagga ttttttattt ttctttttcc aaatttgata gagtagtttg ccatattctt
    10441 gcacccaacg ataaatcgtc gtatgagaaa cgttaatgcc acgatcatat aagatttctt
    10501 gaacttcacg atagctaagg ttataacgaa gatagtagcc cacggctaca ataatcacat
    10561 cctgctgaaa ttgctttcct ttaaaatgat tcatcgtcat tcctcctgct atctttttct
    10621 attattctac cttatttgat agtagattta aaactttgca acagaaccaa cagggctata
    10681 gtataagcca tacttaaaac agattttaca atccgtcaca ttccaaccat ataatccttg
    10741 ttcgcaacca tagcgtatcc cttccataac tgcattttga aatgattgat ttaagtatcc
    10801 aagagaaacc gagctctcat actgcattcc acttcccaac ggaagcggtg atacagataa
    10861 accaatggaa gcccagaaag gatttggcgg cacttcgatg tgaatggtat attctgcatt
    10921 ttttaacggt ctctccatat aaatgactgt aggctctttt agttctatct ccacatgata
    10981 cttttcttgc aacagtgcac taatcacttc catttgtact ttccctaaga aagaaagtat
    11041 aatttcatgt gtcgtagaat ccacataata ttgtagaagc gggtcactgt cggagatttc
    11101 taaaagtgca tcaagtaaca tttccctttg ttgaggtttg ctcggttcaa cagttgtttg
    11161 cagcagaggg agcggatttt caattctctc tctctgtggc aatagctttg tatctccaag
    11221 aacactattt agcttcaaaa actcattttg caaaataaca atttccccgg aataagcctt
    11281 atcaatttta cataattcac caggttctgt tgcaaagttt taaatctact atcaaataag
    11341 gtagaataat agaaaaagat agcaggagga atgacgatga atcattttaa aggaaagcaa
    11401 tttcagcagg atgtgattat tgtagccgtg ggctactatc ttcgttataa ccttagctat
    11461 cgtgaagttc aagaaatctt atatgatcgt ggcattaacg tttctcatac gacgatttat
    11521 cgttgggtgc aagaatatgg caaactactc tatcaaattt ggaaaaagaa aaataaaaaa
    11581 tccttttatt catggaaaat ggatgaaacg tacatcaaaa ttaaaggaaa atggcattat
    11641 ttgtatcgag ccatcgatgc agatgggtta accttggata tttggttacg taaaaaacgg
    11701 gacacacaag cagcctatgc ttttcttaag cggttagtga agcagtttga tgaaccgaag
    11761 gttgtagtca cagataaagc cccctctatt acaagtgcct ttaagaaact aaaagaatac
    11821 ggcttttatc aagggacaga acatcgtacc attaaatacc tgaataattt gattgaacaa
    11881 gaccatcgtc cagtaaagag acgcaataaa ttctatcgaa gtttacgcac tgcctctacc
    11941 acgattaaag gcatggaagc cattcgagga ttatataaga aaacccgaaa agaaggcact
    12001 ctcttcgggt tttcggtctg tactgaaatc aaggtattat tgggaatccc agcttaaatc
    12061 atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac caaatttgga
    12121 aaaagaaaaa taaaaaatcc ttttattcat ggaaaatgga tgaaacgtac atcaaaatta
    12181 aaggaaaatg gcattatttg tatcgagcca tcgatgcaga tggtttaacc ttggatattt
    12241 ggttacgtaa aaaacgggac acacaagcag cctatgcttt tcttaagcgg ttagtgaagc
    12301 agtttgatga accgaaggtt gtagtcacag ataaagcccc ctctattaca agtgccttta
    12361 agaaactaaa agaatacggc ttttatcaag ggacagaaca tcgtaccatt aaatacctga
    12421 ataatttgat tgaacaagac catcgtccag taaagagacg caataaattc tatcgaagtt
    12481 tacgcactgc ctctaccacg attaaaggca tggaagccat tcgaggatta tataagaaaa
    12541 cccgaaaaga aggcactctc ttcgggtttt cggtctgtac tgaaatcaag gtattattgg
    12601 gaatcccagc ttaaatcata gataccgtaa gggattttat tctttattta aaactttgca
    12661 acagaaccta tgatcggttt tgttccttat ttagttgata cggacagcgc aacgataaaa
    12721 tcaaacctgg aagaactgta taagcaacat aaagaagata acttggtttt ccaaaatatt
    12781 atcaagcgaa gtaataaagt aagtacctgg tctaaaaacg gcattacaga gcataaaggc
    12841 tatgacaaaa aagttttatc catgtataag aacgtatttt ttgaaatgct tgagcgaatt
    12901 attcaattag aaaacgaaaa agaatagaat cacaaatcac aagtgattaa tcacaaatca
    12961 cttgtgattt gtgattgttg atgataaaat aagagtaaga agaaatagaa agaagtgagt
    13021 gattgtggga aatttaggcg cacaaaaagc aaaacgaaat gatacaccaa tcagtgcaaa
    13081 aaaagatata atgggagata agacggttcg tgttcgtgct gacttgcacc atatcataaa
    13141 aatcgaaaca gcaaagaatg gcggaaacgt aaaagaagtt atggatcaag ccttagaaga
    13201 atatatacgg aaatatttac ctgacaaact ttaaaaggag tgaaaatgaa atggcagtta
    13261 cgtatgaaaa aacatttgaa atagagatca ttaacgaatt atcggcaagc gtttataatc
    13321 gagtattaaa ctatgttttg aaccatgaat taaataaaaa tgactctcaa ttattggaag
    13381 tcaatttatt aaaccaatta aagcttgcaa aacgtgtaaa tctttttgat tattctttag
    13441 aagaattaca agccgttcat gagtattggc ggtcaatgaa tcgttactca aaacaagttt
    13501 tgaataaaga gaaagtggct taatatggca aatatagtca attttactga caaacaattt
    13561 gagaatcgct taaatgataa tttagaagaa ttgattcaag gaaaaaaagc ggttgaatcg
    13621 ccaaccgctt ttttacttgg tgggcaacca gggtcaggga aaaccagttt gcgatcagca
    13681 atttttgaag aaacacaagg gaatgttatt gtcattgata atgatacctt taaacaacag
    13741 caccctaatt ttgatgaact agtgaaactt tatgaaaaag acgtagtaaa acacgttacc
    13801 ccttattcta atcgcatgac agaagcgatc ataagccgtt tgagcgatca agggtataat
    13861 ttggtgatcg aaggtacagg acgaacaaca gacgttccta ttcaaaccgc aacaatgctt
    13921 caagccaaag gttatgaaac aaaaatgtat gtcatggcag tacctaaaat caactcatat
    13981 ttaggaacaa ttgaacgata tgaaaccatg tatgcagatg atccaatgac agccagggca
    14041 acaccaaaac aagcgcatga tattgttgtc aaaaacttac cgaccaattt agaaaccctt
    14101 cataaaacgg gcttatttag cgatataagg ctatataaca gagaaggagt aaaactctat
    14161 tcaagtttgg aaacaccttc tattagtcca aaagaaacct tagaaaaaga attgaatcgt
    14221 aaagtatcag ggaaagaaat tcaaccgact ttagaacgaa tagagcaaaa aatggttcta
    14281 aataaacacc aagagacacc tgaatttaaa gcaattcaac aaaaattgga aagcttgcag
    14341 ccacctacac caccaatacc caaaacacct aaacttccag gtatttaaac cttaaaaaag
    14401 gaaaagagta gttaccaaaa aacggtaact actctttttt tataaaaaca tttcctcatg
    14461 ttggggtccc gagcgcctac gaggaatttg tatcgataag aaatagattt aaaaatttcg
    14521 ctgttttttt ctaatttcat tttgaggtga attaattggt agttattaga ggtgccctat
    14581 acctaataat ttatctacat tccctttagt aacgtgtaac tttccaaatt tacaaaagcg
    14641 actcatagaa ttatttcctc ccgttaaata atagataact attaaaaata gacaatactt
    14701 gctcataagt aacggtactt aaattgttta ctttggcgtg tttcattgct tgatgaaact
    14761 gatttttagt aaacagttga cgatattctc gattgaccca ttttgaaaca aagtacgtat
    14821 atagcttcca atatttatct ggaacatctg tggtatggcg ggtaagtttt attaagacac
    14881 tgtttacttt tggtttagga tgaaagcatt ccgctggcag cttaagcaat tgctgaatcg
    14941 agacttgagt gtgcaagagc aaccctagtg ttcggtgaat atccaaggta cgcttgtaga
    15001 atccttcttc aacaatcaga tagatgtcag acgcacggct ttcaaaaacc acttttttaa
    15061 taatttgtgt gcttaaatgg taaggaatat tcccaacaat tttatacctc tgtttgttag
    15121 ggaattgaaa ctgtagaata tcttggtgaa ttaaagtgac acgagtattc agttttaatt
    15181 tttctgacga taagttgaat agatgactgt ctaattcaat agacgttacc tgtttactta
    15241 ttttagccag tttcgtcgtt aaatgccctt tacctgttcc aatttcgtaa acggtatcgg
    15301 tttcttttaa attcaattgt tttattattt ggttgagtac tttttcactc gttaaaaagt
    15361 tttgagaata ttttatattt ttgttcatgt tatcactcct gaagtgatta catctataaa
    15421 caaatacaga agttaaacga tttgtttgta attttagtta tctgtttaaa aagtcataag
    15481 attagtcact ggtaggaatt aatctaacgt atttatttat ctgcgtaatc actgttttta
    15541 gtctgtttca aaacagtaga tgttttatct acataacgca tttggaatac caacatgacg
    15601 aatccctcct tcttaattac aaatttttag catctaattt aacttcaatt cctattatac
    15661 aaaattttaa gataatgcac tatcaacaca ctcttaagtt tgcttctaag tcttatttcc
    15721 ataactttag ggttaaccat acgcaagacc aatcactctc ggacaatact catgatttta
    15781 atgataaaat ccatgttaaa cccatagata agaaatacac ctgcaataac cgttacctgt
    15841 ttgtgccaat ttaaaaatgc accacttttt tataatttcg tttgtcaaat taagttagac
    15901 aaatcatctt ttgtgacgta actcaaaaat acttccattg gtgtccgata gtgtaatgat
    15961 tttctaggaa tatgatttcg tttcgatgcc accgattgga taaaggtttc agatacacca
    16021 ttaaaatcca tagctttata caaaccatct ttacgtaata agccatttga atgttcattc
    16081 aatcctcgtt gagaaggtgt tcctggatcc gcaaaataaa ttgaaatatc gttggtatta
    16141 ctaatctttt tccaatttga gaattctttt ccacaatcaa atgtgatgga tttaaataag
    16201 ttttttggga cacaacgaaa ccattgattc agcctatttt caatgtcttt agcctgtctg
    16261 ccttcgggtt tcaaggtaat gatgacttta gatagccgtt caactaatgt gatgaccgcg
    16321 cttttatgtt ttccacccac gatagtgtca ccttccaggt gaccaaattc atgatcaaac
    16381 tgggtatagt ctgtctttct gtctcggatt gaccggcgaa acccttgttt tcctcttttt
    16441 tctttatgac cgtttggttt tctttttccc ttcattggta aatcgtgagt gtcaaaggtt
    16501 ttatctttaa acattcgata cagtgtgcgt accgaacaag caataggaaa ctctgctcga
    16561 ccaataagga catcaggagc ccacccttga acaacctttt tttgaatgta ttcctgttgc
    16621 tcatcaggta aaacaatcgg atgtcttccg cagttacgtt tgtttttctt atattgttta
    16681 tagtagctca ttgcgcttcc accagattta agaaaacgat agaccttata aatagtttgt
    16741 cgagaacgtt gtaacagatt ggctactttt gaaacaggtt gtgattgatt gaaataagct
    16801 tctatcatta cgagttcagt tggtgtaaga tggttatagg tcatttgtac tcactcctta
    16861 taattctttc gtcggaacta ttttgagtgt agcacaaatg acttttttta gttgtctagc
    16921 ttaattttac aatcggcgta attaaaacgg ttgaaaactg taccactaat aactcacaat
    16981 agagagatgt caccgtcaag ttaaatgtac aaaataacag cgaaattttt aaatctattt
    17041 cttatcgata caaattcctc gtaggcgctc gggaccccta tctagcgaac ttttagaaaa
    17101 gatataaaac atcagagtat ggacagttgc ggatgtactt cagaaaagat tagatgtcta
    17161 aaaagcttgt agttaaagct ttttagacat ctaaatctag gtactaaaac aattcatcca
    17221 gtaaaatata atattttatt ttctcccaat caggcttgat ccccagtaag tcaaaaaata
    17281 gctcgacata ctgttcttcc ccgatatcct ccctgatcga ccggacgcag aaggcaatgt
    17341 cataccactt gtccgccctg ccgcttctcc caagatcaat aaagccactt actttgccat
    17401 ctttcacaaa gatgttgctg tctcccaggt cgccgtggga aaagacaagt tcctcttcgg
    17461 gcttttccgt ctttaaaaaa tcatacagct cgcgcggatc tttaaatgga gtgtcttctt
    17521 cccagttttc gcaatccaca tcggccagat cgttattcag taagtaatcc aattcggcta
    17581 agcggctgtc taagctattc gtatagggac aatccgatat gtcgatggag tgaaagagcc
    17641 tgatgcactc cgcatacagc tcgataatct tttcagggct ttgttcatct tcatactctt
    17701 ccgagcaaag gacgccatcg gcctcactca tgagcagatt gctccagcca tcatgccgtt
    17761 caaagtgcag gacctttgga acaggcagct ttccttccag ccatagcatc atgtcctttt
    17821 cccgttccac atcataggtg gtccctttat accggctgtc cgtcattttt aaatataggt
    17881 tttcattttc tcccaccagc ttatatacct tagcaggaga cattccttcc gtatctttta
    17941 cgcagcggta tttttcgatc agttttttca attccggtga tattctcatt ttagccattt
    18001 attatttcct tcctcttttc tacagtattt aaagataccc caagaagcta attataacaa
    18061 gacgaactcc aattcactgt tccttgcatt ctaaaacctt aaataccaga aaacagcttt
    18121 ttcaaagttg ttttcaaagt tggcgtataa catagtatcg acggagccga ttttgaaacc
    18181 acaattatga tagaatttac aagctataag gttattgtcc tgggtttcaa gcattagtcc
    18241 atgcaagttt ttatgctttg cccattctat agatatattg ataagcgcgc tgcctatgcc
    18301 ttgccccctg aaatccttac atacggcgat atcttctata taaaagataa cccgtggtgc
    18361 tagttaattt tttcctagag gaaaatgtct aaacatgttg gtaaatcaac aaaaaaacgc
    18421 atatagtagt ctcaaaactc ccaagaaatg ggctctataa tttatgggac tgatgaatca
    18481 gaattgattc ttcagcccca ttttcatttt aggtattaaa aaacatatcg ttctctagta
    18541 tgattaaatc accacaaaat aaacaactga gaggacgata cgctatatga atgattctat
    18601 caaaaaaatg ctgagaataa cagagaaaga tttgatgatt acagaggtct cttacgagac
    18661 ccttcagaag aaaaagacgt tggtcgtcga tgctgttctc tcgcctactc ctcgtgcttg
    18721 tagaagttgt ggttctactg tggtagatgg aaacgggaaa gcaattatag tgaaaaatgg
    18781 aaaaaaggaa acgattgtcc gttttgaaca atacaatcat atgcctttgg ttatgcgcct
    18841 aaaaaagcaa cgctatacct gtaaaaactg tcgcacccat tggacggctc aaagttattt
    18901 tgtccaaccc agacattcaa tcgcaaatca tgttagatat aaaattgctt ctttactgac
    18961 tgaaaaagta tctttatctt ttattgcgaa aagctgtcag gtatctttga ccaccgttat
    19021 tcgtacattg aaagagttta aaagctattt accaaagcaa tctaagaaga tcctccccag
    19081 agtattgatg gttgacgaat ttcgttcgca tgcttccata gaagataaga tgagctttat
    19141 ttgcgcggat ggcgaaacag gaaaattaat agatgttttg cctacgcgta aattacctcg
    19201 attaacaagc tatttcttag gttgtaccaa tccagaagaa gtagaattct tggtgacaga
    19261 catgaacgcc gcctacttcc agctcaccaa acgtgttctg ccaaatgcga aagtcgtgat
    19321 tgatcggttt catattgtca aacacatgaa tcaagcgttc aatgagttgc gtatccgtga
    19381 aatgaatgaa cttcgtaaag ccggacagaa aagccaggca gaaaaactga aaaagaactg
    19441 gcgctttttg ctaaaaaatc gtgcaaacat caaccattat gaatacaaaa catggaaaag
    19501 tttccgagca ccaaaatacc catttcttac tgaagcaatg atgattgatc gattgcttga
    19561 gttttctccg cccctaaagg aggcgtatcc cttttttcat gaattagttg aagcctttcg
    19621 agacaaagac cctgacttat ttttctcctt attggcagaa cttcccgaaa cgttagatga
    19681 cagctttcgg gaaaagcttc aaaaccttct gacctatgaa gaaggcatca ccaacgcaat
    19741 gatctatcct tattccaatg gaaaaataga agcgaagaat acccacataa agacaatgaa
    19801 acgagtatcc tacggattta aatcatttga gaacatgaga attagaatct ttttgatcaa
    19861 tcaattaatc aatgtaagat aacaaaaaat ctgagccaga atgtggttca ttctgactca
    19921 gatttgattt tgcacaactc atcagtcctt attgacaaag agccataata ccttgatttc
    19981 agtacagacc gaaaacccga agagagtgcc ttcttttcgg gttttcttat ataatcctcg
    20041 aatggcttcc atgcctttaa tcgtggtaga ggcagtgcgt aaacttcgat agaatttatt
    20101 gcgtctcttt actggacgat ggtcttgttc aatcaaatta ttcaggtatt taatggtacg
    20161 atgttctgtc ccttgataaa agccgtattc ttttagtttc ttaaaggcac ttgtaataga
    20221 gggggcttta tctgtgacta caaccttcgg ttcatcaaac tgcttcacta accgcttaag
    20281 aaaagcatag gctgcttgtg tgtcccgttt tttacgtaac caaatatcca aggttaaacc
    20341 atctgcatcg atggctcgat acaaataatg ccattttcct ttaattttga tgtacgtttc
    20401 atccattttc catgaataaa aggatttttt atttttcttt ttccaaattt gatagagtag
    20461 tttgccatat tcttgcaccc aacgataaat cgtcgtatga gaaacgttaa tgccacgatc
    20521 atataagatt tcttgaactt cacgatagct aaggttataa cgaagatagt agcccacggc
    20581 tacaataatc acatcctgct gaaattgctt tcctttaaaa tgattcatcg tcattactcc
    20641 tgctatcttt ttctattatt ctaccttatt tgatagtaga tttaaaactt tgcaacagaa
    20701 ccctttgtgg tatcttttga agcagcctct ttcttatcac cgccgctact gttcacagca
    20761 actatgaaaa aggctaaaaa tatccagccg atcattttca aaatagatac ttttccattc
    20821 ttcttctttt tgaaaagctt atcaaagaag cttctcttct cgtggttagt attggtattt
    20881 ttggtgtttt tgttgttcat tcttaaatct cccttaattt aattttcaaa cgctcttagg
    20941 aacgttttta acgtttctta tggttggttt tggtttggct ggtgtgccat ttcacaactt
    21001 ttctagcaac ttctctagtt gtgatcccgt gtattttgca ctctattatt ggaaaaaatt
    21061 tctctgaagt aaaccctaca caaacgccaa ttagttcttt ttggttggct tgatctcgga
    21121 cggggtggaa agtggctttt gtaccaagct tattttgctg gcttggtgta agggctcctc
    21181 gtgtttttac ttccttatcc tttttaaaac taccaagcat gtggcatgcc ctcactttct
    21241 tggtttcctt gagagggcgc tggagctgta ttttctaact ccttgaaatt atggataatt
    21301 aagttcatga atatcaataa cgtaagaaaa aacaaagcca ttctggaatt attgtaaatt
    21361 ccaaaaaata gtgttaaaat tgccaaagaa agcttgatat tattaagttt tctaatcatt
    21421 tctaaatctc cttagtggtt atttggtaaa tggtttggta gcttttaggg cgtgtggtta
    21481 cccctaaaag taaatggtgt ggctcgttca ttttattgct ttggtcagcg gtaaatggac
    21541 gggctttttt tatgctttgt tctggtcgtt ttgtcgctct tcaattagct tggtagcgac
    21601 ttttacaatc tctttccagc gatcactctc caagttggtc tttgattgga aagctttttg
    21661 tacagtcacg aggctaacac ctttttgtcc ttccctctcg ccttttttaa cggttaatct
    21721 ttcagcaata tcgctgtatg ttatatcatg aagccttaat aacgctttaa gttgatcttt
    21781 ctcgtctagg ttcttaaaag cgttcaataa atcttccttt ttctccaact taccacctcc
    21841 cttccgattt ttagttagaa atcgctccaa gggtcttcct cttcttctgg cggctttctc
    21901 actaagtatt cattttcctt tataccaacg attttccgcc actcttgttc ccaatcttgg
    21961 ttattatcat agtttttgga aagttcttgg atacgcttct ccagctcctc tattttctga
    22021 tctctttccc gatctgcttc ctcatatcct attcggattc tttccagctg ttaggcttct
    22081 cgttcacgct tcttttcctg taataacata gccagcaaaa tgagctcttc cactagttag
    22141 ctccctcatc gctgattttt ccatctctaa gagcttctcg ataaacattt aaaatttgtt
    22201 tatcagtgaa gtgggagcga tatttcacgg tgtctacata gttttcacga aaataagtct
    22261 tgtaatcgct gataacgtaa gcttgcttgg ctatttggat ttcttgcttg ttgtttttgg
    22321 tctcaagttg attattttcc ttgcttaagt tatagcaatt tacaccaagg ataataagag
    22381 cgatagctaa aactccaata atcacgggat aaattacttg cttcattttc atttctttca
    22441 tattactttc tctcctttaa ttggttggtt tggtattttc aaaagagaac ggtactcatt
    22501 ccgccattac gctttaaccc tcgtaccctt tcgatatatt tatattacta ccagtggtag
    22561 tataatttaa tagatttttt aaaataaatc cataaataac ccttggaaat tatctcaaat
    22621 acacaaaaac cccatagcca taacggttac aggttttttt cgattattta aacaactgtt
    22681 tttgtctggt tctggtaaat gatcggctaa aattcctaag cgatcatgtt cacatttggg
    22741 gcagccactc gcaacggatt cccttaaaat cgtttgaaaa gtcgatccgc acaccttaca
    22801 ctcgaaaaac tcaaggctct ctgccgattt tgggaagccg tctggcgcct ttggagcggt
    22861 cggaacgtgt tggagtttca taccttcaag gcgtgagtac aatctaataa gatcggcttt
    22921 gcgttcggct gggctagttt ggttagttgg tgctgtattt ggtgtttggt tagtgttttc
    22981 catgttggtt atagctcctt tattttgctt ggtttggtat aggactagaa ggctctaaaa
    23041 ggagccctcg cgccttacaa gtactttggt ttattggatt agattgctga caggtgttac
    23101 cattccacgt tggaaaggtc gatctctgga gttggatcgt tgacagcttt ttcctctcct
    23161 tccatatttt ccaactcttg ttggtactct actaaagaag ctccctcgct gcttcttagg
    23221 cgttcttgca tatcggttat tgttagctta tcaaacttca atcttacatg agtgatcttt
    23281 ctggagtcgc tagaattctt ttccactgtt aggcttagct ctggaaagta ctctttgaga
    23341 gcagcgatag caggctttag aacgttgttt ataaaatctc tgttatttct cgttggattg
    23401 actcctaaaa tttctcttaa atcattaatc cttttataat acattcctgt attccaaaag
    23461 gtagaaagct ctaagaaaag gatcatggag tacttacttt ttaacttcac aaagtctctt
    23521 agattaaata aaatgtattg gttaaccact tctgaaaacc actctaaata ttctggattg
    23581 atccgcgctg ttacttctag cgtatgctta tttattaccc accttgctat agcgggcgcg
    23641 gttatgatct cattttcatt ttcatctacc atataaatag agtgtaaatt tatccccgtt
    23701 tggagtaatt ccatttgctc gttaattgtc agaggttctg gctggtttga aaagtaacga
    23761 tcaactattt gtttgttggg ttctgttgca aagttttaaa tctactatca aataaggtag
    23821 aataatagaa aaagatagca ggagtaatga cgatgaatca ttttaaagga aagcaatttc
    23881 agcaggatgt gattattgta gccgtgggct actatcttcg ttataacctt agctatcgtg
    23941 aagttcaaga aatcttatat gatcgtggca ttaacgtttc tcatacgacg atttatcgtt
    24001 gggtgcaaga atatggcaaa ctactctatc aaatttggaa aaagaaaaat aaaaaatcct
    24061 tttattcatg gaaaatggat gaaacgtaca tcaaaattaa aggaaaatgg cattatttgt
    24121 atcgagccat cgatgcagat ggtttaacct tggatatttg gt
//
