LOCUS       NZ_CP059775            27191 bp    DNA     circular CON 06-NOV-2023
DEFINITION  Enterococcus faecium strain A3895 plasmid pA3895_P3, complete
            sequence.
ACCESSION   NZ_CP059775
VERSION     NZ_CP059775.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14675384
            Assembly: GCF_012933265.2
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27191)
  AUTHORS   Veeraraghavan,B., Vasudevan,K., Arumugam,A., Solaimalai,D. and
            Bakthavatchalam,Y.D.
  TITLE     Complete genome of vancomycin resistant Enterococcus faecium
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27191)
  AUTHORS   Veeraraghavan,B., Vasudevan,K., Arumugam,A., Solaimalai,D. and
            Bakthavatchalam,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2020) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore, Tamil Nadu 632004, India
REFERENCE   3  (bases 1 to 27191)
  AUTHORS   Veeraraghavan,B., Solaimalai,D., Vasudevan,K. and Arumugam,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-APR-2020) Department of Clinical Microbiology,
            Christian Medical College and Hospital, Ida Scudder Road, Vellore,
            Tamil Nadu 632004, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method :: CANU v. v. 1.7; UNICYCLER HYBRID v. v. 0.4.6
            Assembly Name                     :: A3895
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.42x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/06/2023 04:47:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,060
            CDSs (total)                      :: 2,970
            Genes (coding)                    :: 2,868
            CDSs (with protein)               :: 2,868
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 35 of 102
            Pseudo Genes (incomplete)         :: 68 of 102
            Pseudo Genes (internal stop)      :: 25 of 102
            Pseudo Genes (multiple problems)  :: 20 of 102
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059775.1.
            Bacteria and source DNA available from Christian Medical College.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="A3895"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pA3895_P3"
                     /geo_loc_name="India: Vellore"
                     /lat_lon="12.9165 N 79.1325 E"
                     /collection_date="2019"
                     /collected_by="CMC Vellore"
     gene            complement(join(26358..27191,1..329))
                     /locus_tag="HI845_RS14765"
                     /old_locus_tag="H4J14_014760"
     CDS             complement(join(26358..27191,1..53,53..329))
                     /locus_tag="HI845_RS14765"
                     /old_locus_tag="H4J14_014760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_086953888.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKWV
                     KQFKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANKHL
                     YPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSKRGI
                     QISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIVTDLT
                     YVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFHTDRGK
                     EFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLEL
                     FDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
                     /name="IS3 family transposase"
     gene            complement(735..989)
                     /locus_tag="HI845_RS14775"
                     /old_locus_tag="H4J14_014770"
     CDS             complement(735..989)
                     /locus_tag="HI845_RS14775"
                     /old_locus_tag="H4J14_014770"
                     /inference="COORDINATES: protein motif:HMM:NF013677.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000199136.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYLP
                     DQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
                     /name="transposase"
     gene            complement(1182..1457)
                     /gene="prgO"
                     /locus_tag="HI845_RS14780"
                     /old_locus_tag="H4J14_014775"
     CDS             complement(1182..1457)
                     /gene="prgO"
                     /locus_tag="HI845_RS14780"
                     /old_locus_tag="H4J14_014775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            complement(1429..2382)
                     /locus_tag="HI845_RS14785"
                     /old_locus_tag="H4J14_014780"
     CDS             complement(1429..2382)
                     /locus_tag="HI845_RS14785"
                     /old_locus_tag="H4J14_014780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            2994..4487
                     /locus_tag="HI845_RS14790"
                     /old_locus_tag="H4J14_014785"
     CDS             2994..4487
                     /locus_tag="HI845_RS14790"
                     /old_locus_tag="H4J14_014785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            4622..4918
                     /locus_tag="HI845_RS14795"
                     /old_locus_tag="H4J14_014790"
     CDS             4622..4918
                     /locus_tag="HI845_RS14795"
                     /old_locus_tag="H4J14_014790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(4942..5901)
                     /locus_tag="HI845_RS14800"
                     /old_locus_tag="H4J14_014795"
     CDS             complement(4942..5901)
                     /locus_tag="HI845_RS14800"
                     /old_locus_tag="H4J14_014795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222573.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHCLNRSRQTIHKVYLFF
                     KQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIRCS
                     ARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFKSITF
                     DCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDESF
                     IQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
                     /name="IS30 family transposase"
     gene            6084..>6689
                     /locus_tag="HI845_RS14805"
                     /old_locus_tag="H4J14_014800"
                     /pseudo=""
     CDS             6084..>6689
                     /locus_tag="HI845_RS14805"
                     /old_locus_tag="H4J14_014800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358225.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            6764..7444
                     /locus_tag="HI845_RS14810"
                     /old_locus_tag="H4J14_014805"
     CDS             6764..7444
                     /locus_tag="HI845_RS14810"
                     /old_locus_tag="H4J14_014805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            7581..>8534
                     /locus_tag="HI845_RS14815"
                     /old_locus_tag="H4J14_014810"
                     /pseudo=""
     CDS             7581..>8534
                     /locus_tag="HI845_RS14815"
                     /old_locus_tag="H4J14_014810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /name="IS256-like element IS256 family transposase"
     gene            complement(8584..9264)
                     /locus_tag="HI845_RS14820"
                     /old_locus_tag="H4J14_014815"
     CDS             complement(8584..9264)
                     /locus_tag="HI845_RS14820"
                     /old_locus_tag="H4J14_014815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            9395..9847
                     /locus_tag="HI845_RS14825"
                     /old_locus_tag="H4J14_014820"
     CDS             9395..9847
                     /locus_tag="HI845_RS14825"
                     /old_locus_tag="H4J14_014820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000751236.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNKK
                     MSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSELVS
                     YKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
                     /name="hypothetical protein"
     gene            9861..10550
                     /locus_tag="HI845_RS14830"
                     /old_locus_tag="H4J14_014825"
     CDS             9861..10550
                     /locus_tag="HI845_RS14830"
                     /old_locus_tag="H4J14_014825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000718009.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFEE
                     EDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKNDIE
                     TTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFLRWK
                     SYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNPVAGT
                     YYVVQNI"
                     /name="hypothetical protein"
     gene            10675..13026
                     /locus_tag="HI845_RS14835"
                     /old_locus_tag="H4J14_014830"
     CDS             10675..13026
                     /locus_tag="HI845_RS14835"
                     /old_locus_tag="H4J14_014830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="WP_000344083.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQV
                     ELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVYTP
                     YLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLNVNY
                     LEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGNSGNY
                     VRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKGLLSSA
                     GDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTTEELNNI
                     FSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAVDLDMLGE
                     EILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMSTGYSGNLG
                     FPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNYIAKYNQKVI
                     NQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRKIYDEYRNKLT
                     NSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWLGDLMTCWGEVK
                     KLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDSTALSALKTYYCDK
                     GAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFIDKIVNNSLGTDFT
                     YLDFIGDEGKVANGFSEKIIQFQENRSKLN"
                     /name="glycoside hydrolase domain-containing protein"
     gene            13106..13501
                     /locus_tag="HI845_RS14840"
                     /old_locus_tag="H4J14_014835"
     CDS             13106..13501
                     /locus_tag="HI845_RS14840"
                     /old_locus_tag="H4J14_014835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002304891.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIVD
                     YFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKKKE
                     YNYIVKAKVSKRFIFNPKLEIYSVVIE"
                     /name="hypothetical protein"
     gene            13826..14443
                     /locus_tag="HI845_RS14845"
                     /old_locus_tag="H4J14_014840"
     CDS             13826..14443
                     /locus_tag="HI845_RS14845"
                     /old_locus_tag="H4J14_014840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001224538.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFKR
                     PEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTASY
                     KQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPPEFP
                     AIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
                     /name="recombinase family protein"
     gene            14484..14783
                     /locus_tag="HI845_RS14850"
                     /old_locus_tag="H4J14_014845"
     CDS             14484..14783
                     /locus_tag="HI845_RS14850"
                     /old_locus_tag="H4J14_014845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="WP_000366408.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFLV
                     CGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
                     /name="BRCT domain-containing protein"
     gene            14817..14984
                     /locus_tag="HI845_RS14855"
                     /old_locus_tag="H4J14_014850"
     CDS             14817..14984
                     /locus_tag="HI845_RS14855"
                     /old_locus_tag="H4J14_014850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000824191.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCPK
                     CHRRYGVHGT"
                     /name="hypothetical protein"
     gene            complement(15029..15634)
                     /locus_tag="HI845_RS14860"
                     /old_locus_tag="H4J14_014855"
     CDS             complement(15029..15634)
                     /locus_tag="HI845_RS14860"
                     /old_locus_tag="H4J14_014855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002321606.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERPE
                     FQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNEL
                     LDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRL
                     VFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
                     /name="recombinase family protein"
     gene            15759..18746
                     /locus_tag="HI845_RS14865"
                     /old_locus_tag="H4J14_014860"
     CDS             15759..18746
                     /locus_tag="HI845_RS14865"
                     /old_locus_tag="H4J14_014860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="WP_000343406.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPAT
                     RLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTKLI
                     KSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITTFSR
                     FVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLADDSH
                     KEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKKLALLV
                     AFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSDIVDLVM
                     SSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYRKFRKFIP
                     DILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYYIHEYPEQT
                     NKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLLEQLDLPSSA
                     NEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKEDKSFRRRIQQ
                     LLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSESCNIGFSPVSK
                     EGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDGHMASADGIRYIT
                     PQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSLYLLEGFLNQPSEL
                     TPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDANAHYGELDTLSQNSI
                     NMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGKAITEYGKVYKTKHQL
                     RYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYDGMEEQLNALGLVTNAI
                     IYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVGKYTFRYEAELSNGKLRP
                     LNVEEF"
                     /name="Tn3 family transposase"
     gene            18895..>19104
                     /locus_tag="HI845_RS14870"
                     /old_locus_tag="H4J14_014865"
                     /pseudo=""
     CDS             18895..>19104
                     /locus_tag="HI845_RS14870"
                     /old_locus_tag="H4J14_014865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /name="DNA topoisomerase"
     gene            19239..>19421
                     /locus_tag="HI845_RS14875"
                     /old_locus_tag="H4J14_014870"
                     /pseudo=""
     CDS             19239..>19421
                     /locus_tag="HI845_RS14875"
                     /old_locus_tag="H4J14_014870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            19397..19753
                     /locus_tag="HI845_RS14880"
                     /old_locus_tag="H4J14_014875"
     CDS             19397..19753
                     /locus_tag="HI845_RS14880"
                     /old_locus_tag="H4J14_014875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_029756604.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLTN
                     IENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVTIG
                     KVIQAIYGEKCKFN"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(20267..20434)
                     /locus_tag="HI845_RS14885"
                     /old_locus_tag="H4J14_014880"
     CDS             complement(20267..20434)
                     /locus_tag="HI845_RS14885"
                     /old_locus_tag="H4J14_014880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="WP_005228365.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITVI
                     TEPDAKTQSR"
                     /name="cysteine-rich KTR domain-containing protein"
     ARG             complement(20523..22462)
                     /name="tet(S)"
                     /gene="tet(S)"
                     /gene_name="tetracycline-resistant ribosomal protection
                     protein"
                     /tool="rgi"
                     /drug_class="tetracycline antibiotic"
                     /identity="99.84"
                     /coverage="100.78"
     ARG             complement(20526..22447)
                     /name="tet(S)"
                     /gene="tet(S)"
                     /gene_name="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            23141..23821
                     /locus_tag="HI845_RS14900"
                     /old_locus_tag="H4J14_014895"
     CDS             23141..23821
                     /locus_tag="HI845_RS14900"
                     /old_locus_tag="H4J14_014895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            24019..24624
                     /locus_tag="HI845_RS14905"
                     /old_locus_tag="H4J14_014900"
     CDS             24019..24624
                     /locus_tag="HI845_RS14905"
                     /old_locus_tag="H4J14_014900"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            24640..25212
                     /locus_tag="HI845_RS14910"
                     /old_locus_tag="H4J14_014905"
     CDS             24640..25212
                     /locus_tag="HI845_RS14910"
                     /old_locus_tag="H4J14_014905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(25685..26257)
                     /locus_tag="HI845_RS14915"
                     /old_locus_tag="H4J14_014910"
     CDS             complement(25685..26257)
                     /locus_tag="HI845_RS14915"
                     /old_locus_tag="H4J14_014910"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_073120187.1"
                     /translation="MCQKNCCHSIISKENLLNQDFSTETICEKWAADITYIPTKKNGWC
                     YLSSIMDLHTKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREV
                     EQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGF
                     YNRNRIHSSIHYLTPQEFEELAKEKMA"
                     /name="IS3 family transposase"
     Typing          2995..4487
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 catcgctgat atagggtaaa gatgcttatt cgcatcgatt acttgtctct tcgtccgaat
       61 atcagcgctg cttgctttaa aatatcattt tccatttcta attgctggtt tcttttacgt
      121 agttctaaca attctttttg ttcaggcgta agattatctt tttctttgaa tgaaccactc
      181 gttttaaatt gctttaccca tttgtcaaat gctgaagccg ttagttcata ttctcgaatg
      241 atttctacac gtggctttcc agctaagtaa agattgacga tttgttgctt gaattcttgt
      301 gaaaaagttc ttcgtgttct cttagacata aaaattcctc ctggtatgtt ttcttctagt
      361 ctacacacct taatttttct gtctagttaa ttgtagccta tccatgatcg gtttattaga
      421 cctttgaggt ctatattttt taactacaat cgaccttaaa tttaattgtt tcattagctt
      481 ttggacatgt ttaagagata ctgaaatccc ttcttttaat aaaacttgat ggatctttgt
      541 ggcaccatag cgttgtttat tcgtaaaaaa aattgttgaa atcttctttt tcaacttatt
      601 atttctgatt tctgtagctg tcaacggttt attcttataa aaataataga cacttctagg
      661 gatttctaat aaccgacaca acaaagaaac agtgtaatcc ttacaccatt tttcaataaa
      721 ttgaacaagc gaatttaggt tttccgagag aatatggctg cggctttttt taagatttca
      781 agttcctcat ttaaacgagc attttctttt ctcagttcag ctacttcttt tccagtcagt
      841 cctgtggact gatcaggtaa atataaattc ttccatttgt aaatcgttgc ttcagataag
      901 ccatattctt tcgctaaccc tcgaacagaa cgtccagttt gattcagttc aacaatcatt
      961 tgtttaaaat tttcttcata tcgggtcata aaaattcatc ctctcgtaga taagtttaat
     1021 ttattcttgt ctctacgaaa agctgtctaa gatttgatac taacaccaaa tgttgtatac
     1081 ccccaaacaa tacacatatt ttgaaggatt aggattaata aagctaaaaa tatagtaagt
     1141 atactaaata tatttactat atctagtata cttactatat tttaatcttt tgatcgtcta
     1201 ttatatataa tccgttcctc gtcgtttaaa gtatcaacat aggcgtccat tgcaagtttg
     1261 actatttcat acataggaat atcttttgca taactaagat cccgaatggt ttttagtacg
     1321 ggaggatcta cttgaactgg ttttctttct ttcgcagtgt actttcgttc ccctaactcg
     1381 acattaatat catctttaat tgaaatatct tcagcaccaa ttttcttctt atctttgttc
     1441 gttggtaata atgccattta gtttaatctc ctttccaaga ggtaggatat gattggccat
     1501 tgagtcagca tatttaggtg tataatcaaa tccttcaata tcaccatgtt gttcatagta
     1561 ttcaattctt tcttctaatt ctgtaaagat gtctgcaaaa atagcccacc atcttcgatc
     1621 tacataatca tttaattgga taccattctc accatacatt tctaaccgat ccgagccttt
     1681 aacaatgctt ttaaaaatgt ttgattcacc atacttatca attgtttttt gatagtttgc
     1741 gtgttgagag gaacgtcgca ctgagaaaag aacaggcaaa attccaatga tttgaagatg
     1801 agactcttca aaattcgtga caatcggaac taaaacttta ttaataaaat cttctgttcc
     1861 ttccattgcg taccgtttta attcttgcat tgcaataata taatctgcag cagttaagaa
     1921 tgcacgaacc acattatctg ttgatggtgg gcagtcgata aagatataat cgaaattttt
     1981 tctcaattct tctaaaggtt taatgaaggc caatgatctc ttacgacgat caggatattt
     2041 ttcggacaag tattcattaa gttcttcaga tccaggagag ccagccataa tatataaatg
     2101 tggacttact tgagtaatac ctgaaaccca gtcccctttt ttgattgctg cagacatgga
     2161 tcgatcaaag ctagtaattt gatacgttga tccaatgttg gaagtagtat ttctttgttg
     2221 gtcataatca attagcaaca cgtctttttc aaaaagttga ctagaaacaa tcgctaataa
     2281 atcattgtct gtagtcttac caatgccgcc ttttctacct gtaagcatta caacttttcc
     2341 tagtttatct gatgttttaa atgcagtccg taagttttcc atagttccct ccaatttcct
     2401 atactaaata tatttagtat acttcatata cttaatatat tcgatatatc taatatactc
     2461 caaattgata agaattcaga ctttataagg aatatagtgg atatactaaa tatatttgct
     2521 atattcagta tatcagatat attcaaaatg tcaaaatata tttgtgcgtt ttgcgttgac
     2581 aatttagagt gaaaagaggt aaacttaatt ctatagaaac cacagataat tcactattta
     2641 caaagtagca aaagcagtgg tactctttaa acagaaaaat tacataaaaa aaagagacgg
     2701 aaataattga ttttagcaga atcaattatt tctgaatcac atggttagga catgtgttca
     2761 cgctcgtctc aagaatatgt aagtagctac caactactta tattaaaagt tgatcggata
     2821 ccttttccga ttgcctttat tctaccaaaa aaaggcgagc aactcaacag aagaacgttt
     2881 atttagtgta cttaaattaa atattcttaa acactgaaga gagaacacat actatggctg
     2941 agattaaagc taaactgtgt tctctttttg tttgagaaag gacgttacaa tcgatgttga
     3001 gcgaaattta ttcagctatt cttaaaaacg gcttacgtac atacaaatat cgaaacagca
     3061 ccatgaaacc tgcaggtcat attgattcca gtaggagtgg tgctatcttt gcgtaccgta
     3121 gcaagcaatt aatgaatgtt gggcgtggta tggtcattac ttcggaagaa gctattttag
     3181 agaacgaaaa gaaactaacg cattggacac ctaataccta tcgctttggt acttatgcgg
     3241 atgattatcg aacagtggtt aaaggtcatt ctgagaaaaa cttaagtcaa atcaacacat
     3301 ttgtagttga tatcgattca aaagagaacc atcaaggcga aattatttta gcctgtttag
     3361 atcaagtggg ctacatgcca acgctaattt tagaatcaga tcatggttat caagtttatt
     3421 ttgtactaaa gacaccaggc tatgtcacaa agaaaagcaa tttcaaggtg atcgatgtag
     3481 caaaaaaaat ttcaaaaaca attcgtctac agttggctga aaaattgtcc ggagtggatc
     3541 taggatgtaa ccacttcgga attgctcgat tcccacaaga aaataatatt gtttttaaag
     3601 aaatgaacta tcagtattct tttgctgact ggattcaatg gtcgatgaag cttgaatcag
     3661 atcaaaaaac aaaagaagat cgagaacgaa aactaattgt ctttcctgag aaaaaagaaa
     3721 ttcgtcaagt agatgaaccg tggttcgata tgttacttca taaagcaaac atcgtcggcg
     3781 gagaaggacg tcttggtcga aataatgtga ttttcacgct ttctttagct tattactctt
     3841 caggttatgc attggatact tgcgaataca atatgttcac attcaacgaa cggttacagg
     3901 aaccgctatc tgaagcagaa ttagtaaaga ttgtacgtag tgcttattct ggtaattatc
     3961 aagcagcaag cagagaattc attattgaat tgtgccagca atgggtttca ccaaccttaa
     4021 aaaataatga tctgttcatt caacgacgtg gctggtggaa atttaaaaag ccacgagatc
     4081 aaagaaaata tagtcataaa aatgaatgga aagaagatct attggcttat ctaagcgaaa
     4141 aaagtcttgc tagtgagcct tatttgaacc tgtcaaaaaa agaattggct tcacaactaa
     4201 cgatgcccaa gcgaacactt gataagatct taaatgagtt acgagaggag aataaagtct
     4261 tctacaaggt aacacgagga agaaatggcg gaatgatcat tgcttcagtc aaaacgttgt
     4321 tcgcgagggt tattcaacta agtaaagaaa agagactaga ttattcaaca aggatcacag
     4381 aggtatttgg actcaacgag agcttagtag aagagacatt tagacaatta tcaaccccct
     4441 tgaaccctct taaagaagtg aatctttttg aagtagatac aggttgaaaa ataaaaggtg
     4501 caaattgcct tatacaatat atctatgata cttctgtagg tgttgctccc tttgcctagc
     4561 tacgtgtagg tggtatactt ataactgcgt atgcagtctt atgtatcatg gaggaagttg
     4621 tatgtcgtta aaaaattatg tctattcaca tcctgttaat gtgtttatca ttggtcgttt
     4681 gggattatct gtggaagtgt tctgtgagct ttatggtttt aagcagggga ctttgtcttc
     4741 ttgggttacc agggaaaaaa cagttgcttc tttgccgatt gagtttcttc atgggttgtc
     4801 cttagcttct ggggagacta tggatcaggt atatgattgt ttgtgtgtgt tagagcagga
     4861 gtatattgag tataaaatag ctaacgagtt aagaaaaagg aagaagtata tccagtagta
     4921 gtttttattt actcttaatt gtcaaattaa gttagacaaa tcatcaatac ttacgtaact
     4981 caaaaatact tccaaaggtg ttcgataatt cagtgatttt ctaggaatat tatttcgttt
     5041 cgatgcgaca gattgaataa aagattcatc tactgaattg aaatccatag atttcaataa
     5101 accatctcta cgtaacaatc cgttagaatt ctcgtttagg cctctttgag acggcgttcc
     5161 tggatcagcg aaataaatgg caatatcatt ggcattactg atctgtttcc aatttgaaaa
     5221 ttcctttcca caatcaaaag tgatggattt gaatagattt ttcggtacag attcaaacca
     5281 atgatttaat ttgttttcaa tatcaatcgc ttgtctacca cacggtttca atgtgatgat
     5341 aacttttgat aatcgctcaa ctaaggtaat tacagcactt ttatgtttca aacctacgat
     5401 agtgtcacct tcaaggtgac caaactcatt tgagaattgg ctataatctt tttcacgttc
     5461 atgaatagag cgacggaaag cttgttttcc acgtctttct tgatgtccat ttggtttacg
     5521 cttgcctttc atcggtaagt cagaaggatt aaatagcccc tttttgaaca tacgataaat
     5581 ggtacgagca gaacaacgaa taggaaacgc tgcacgacca acaatcacat cgggtgtcca
     5641 tccttgaaca acctttcttt gaatatattc tgattgttcc tcaggtaaaa caagcgggcg
     5701 tctaccacag tttgatttgt ttttcttata ctgttgatag tactctaagg ctgattttcc
     5761 ttgcttgaag aacaggtata ctttatggat cgtttgtctt gaacgattca agcaatgcgc
     5821 agttttcgca acagattgat ttattttgaa ataagactct atcattacaa gttcatccgt
     5881 tgtaagatgg gtataggtca tttgtactca ctccttataa ttctttggac ggaactattt
     5941 tgagtgtagc acaaatgact tttttagttg tctagcttaa ttttacaatc ggcgtactta
     6001 aaaaattggt tcattgagca acctatcgct gctaaagtag caaaggaaaa cgttaaagga
     6061 aagaatttag ggaagaaatc gaaatgaaat cggacgactg gattgaacac acctggcttc
     6121 ctctgaaaag aaatagcaaa cgaaagaaat tttgggtatt gcaattatgg ccattaggaa
     6181 aactttgtag ttacggggca cgacttattc ttgatttaac cgtttactcg attggagtat
     6241 ttggaacggc ttattacttg ataaatgatc ccaataggat tgcagcatca gacattttta
     6301 cagtgctaat gacgttgatt tttgtcatgc tattgtctat ttttactcaa ttagtcatgc
     6361 aatttaccag gcaaaaatta acagcaggaa aacttttcaa aagcctattc gatttaattg
     6421 ttgtaaatgc aattctagcg actttaataa aacaaattga acaatctgga agaacaacaa
     6481 aaggagtgaa ggatttttta ttgacgttta ttcactttgt aaatggacac atgtatttgt
     6541 ttgaagtggg tattattctc ttttttgtcg ggtatgtatc cacgaaactt attaaacgtt
     6601 caattgaaaa agaaattgaa attgacctga ttccgacact tcttggttat gagtacaatg
     6661 ttgattttgg aagatatgac gaattgatcg gttctgttgc aaagttttaa atctactatc
     6721 aaataaggta gaataataga aaaagatagc aggaggaatg acgatgaatc attttaaagg
     6781 aaagcaattt cagcaggatg tgattattgt agccgtgggc tactatcttc gttataacct
     6841 tagctatcgt gaagttcaag aaatcttata tgatcgtggc attaacgttt ctcatacgac
     6901 gatttatcgt tgggtgcaag aatatggcaa actactctat caaatttgga aaaagaaaaa
     6961 taaaaaatcc ttttattcat ggaaaatgga tgaaacgtac atcaaaatta aaggaaaatg
     7021 gcattatttg tatcgagcca tcgatgcaga tggtttaacc ttggatattt ggttacgtaa
     7081 aaaacgggac acacaagcag cctatgcttt tcttaagcgg ttagtgaagc agtttgatga
     7141 accgaaggtt gtagtcacag ataaagcccc ctctattaca agtgccttta agaaactaaa
     7201 agaatacggc ttttatcaag ggacagaaca tcgtaccatt aaatacctga ataatttgat
     7261 tgaacaagac catcgtccag taaagagacg caataaattc tatcgaagtt tacgcactgc
     7321 ctctaccacg attaaaggca tggaagccat tcgaggatta tataagaaaa cccgaaaaga
     7381 aggcactctc ttcgggtttt cggtctgtac tgaaatcaag gtattattgg gaatcccagc
     7441 ttaaatcata gataccgtaa gggattttat tctttattta aaactttgca acagaacctg
     7501 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
     7561 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
     7621 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
     7681 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
     7741 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
     7801 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
     7861 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
     7921 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
     7981 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
     8041 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
     8101 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
     8161 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
     8221 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
     8281 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
     8341 gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat tcaaaatctt
     8401 tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg cgtgaggcta
     8461 aaaatcgatt gattcatgat tatatcgatc aaccaaaata ttcaaaagct tgcgcatcat
     8521 tggatgatgg gttctgttgc aaagttttaa ataaagaata aaatccctta cggtatctat
     8581 gatttaagct gggattccca ataatacctt gatttcagta cagaccgaaa acccgaagag
     8641 agtgccttct tttcgggttt tcttatataa tcctcgaatg gcttccatgc ctttaatcgt
     8701 ggtagaggca gtgcgtaaac ttcgatagaa tttattgcgt ctctttactg gacgatggtc
     8761 ttgttcaatc aaattattca ggtatttaat ggtacgatgt tctgtccctt gataaaagcc
     8821 gtattctttt agtttcttaa aggcacttgt aatagagggg gctttatctg tgactacaac
     8881 cttcggttca tcaaactgct tcactaaccg cttaagaaaa gcataggctg cttgtgtgtc
     8941 ccgtttttta cgtaaccaaa tatccaaggt taaaccatct gcatcgatgg ctcgatacaa
     9001 ataatgccat tttcctttaa ttttgatgta cgtttcatcc attttccatg aataaaagga
     9061 ttttttattt ttctttttcc aaatttgata gagtagtttg ccatattctt gcacccaacg
     9121 ataaatcgtc gtatgagaaa cgttaatgcc acgatcatat aagatttctt gaacttcacg
     9181 atagctaagg ttataacgaa gatagtagcc cacggctaca ataatcacat cctgctgaaa
     9241 ttgctttcct ttaaaatgat tcatcgtcat tcctcctgct atctttttct attattctac
     9301 cttatttgat agtagattta aaactttgca acagaaccaa ttatcttatc gtagatatat
     9361 attataaatt taataagaaa gcgaggtgag aatcgtgaaa aaaacgatac taagtatttt
     9421 ttcagtattt acaatattaa ttgggggcta ttttcttttg aatttagatt ctgttaattc
     9481 aaacgctcaa ataaaagatc aaagagtagc tgaacataat aataaaaaaa tgagtttgac
     9541 caaaaatatc tattctatgt cagatgaaga attgtataaa gaatttggtg atttatccgg
     9601 ggaacagtta gaagaaagta ttccaggaat tagtgactca gataaaattg ttgtcttgtc
     9661 tgctggtggg caattaatgg gagatggcaa atccgaatta gttagttata aacaaaatca
     9721 cagacagttt attgatgtta atactgattc caacgctatt tcgattaagg atctaaaaga
     9781 gcttttaaat agtaaaagaa atgaattaaa gcagataaaa gaaactaatt cagtggaatt
     9841 agagtaaagg aagattcatt atgaaaaaga tttttggtgt ttctgttggg ctacttatga
     9901 tgttaacatt tggaaatgca gtatatgctg ctgagaaaga agttatttca gatccagagc
     9961 agtacgcctc acgatacttt gctgattttg aagaagaaga taaagtactt gcattgccag
    10021 aaggtggttt tttaaaaggg gaagctaaaa ttgtatctat ggataatcca gatataattc
    10081 aaggttcata taattcagaa actgatcctg cttcagtttc agtgacagaa gcaaaaaaaa
    10141 ttgttgctga aaaattcaaa aatgatattg aaactactcc aattatgcct cgaggagcat
    10201 ttccacccga tgttggtact agcggacacc ttcttgtact agcaggagga ggaagctata
    10261 aatcacagcc atttagtggt gcgggatggc gttttggagg tatgggtgta aaaccagctg
    10321 atggtacagg caacttttta cgttggaaat cctacattga cgatggaaga gtaggaaatg
    10381 taaatcaagc caacgcaact aaatctggtt ctattcaagg aatggcattg tatgctcgtg
    10441 aaggattcaa atactttgca ccaaacgggc ctggttggac aatgaatata ggtatttatt
    10501 acacttataa tcctgttgca ggtacgtatt atgttgttca aaatatttaa taaaacagca
    10561 caaagagatt tctttgtgct gttttattat ttttagttgt tgacaaacac taaaatataa
    10621 aatataatca acacataaac gaacgtatgt tcggcaagaa agcaggggat ttttatggat
    10681 gagatggttt taagtactca gaaatggcta aacaagaaat acagtaatgt tacagggttt
    10741 gataaggttc cagaaaatgg gcgaacaggg tggcctacaa tctatggact tattgaagga
    10801 ctacaagtag aacttggtat tactaatcta gtagctaatt ttggacctac cactgaaaaa
    10861 atgtacgata atcaggttac tcctaaatgg ggcaaaaatc tacctaaaaa tattgtattt
    10921 cttattcaag gtgccttttg gtgtaagggg attaatccag gtggcttcga tggggtatat
    10981 actccatatt tagatactgc tgtaaaagag ttgcagactg atgcagggtt taatggaagc
    11041 gctgtaactg gagttttgga tgcgaaatgg gccaaagcgt tatttgatat gagtgctttt
    11101 gttcttgttc ccggcggaga tagtaaaatt agaaaaatgc agcaatggtt aaatgtaaat
    11161 tatttagaat acacgggaat aatgccttgt gatggtattt atcaaagaaa ttcaaatcaa
    11221 gcattaattt ttgcattaca agctgaacta ggatattctc ccagtgaagc aacagggtct
    11281 tatggtaatg ggacaactag taaaacttat cctgtgtctg aaggtaactc gggaaactat
    11341 gtaagaataa ttcaatatgg attatatgtt aatggttatt ttgaagacgg tacattcgat
    11401 ggtattttca ctaaatatat gggtttagaa gtactggcat tccgaaaatt tatggtattg
    11461 cctgaatata ctgaaatagc agatgttgtt gtaataaaag gactattgtc tagcgctgga
    11521 gatattagaa gatctgcaga tggcgcagat acttctacgc aattaactag atctcaaatc
    11581 caaacattgg ttgataatga tataaaaata gttggtagat atcttactgg tactgttgga
    11641 attggaaaag atgaacgaaa taagtatcta actacagagg aattgaataa tattttttct
    11701 aaaaatttat ctgtgtttcc tatctatcaa gatggaggtg cagcattagc ttattttact
    11761 tatgatcgtg gcttatcaga tggtaagaag gctatagatg cagcaaaaaa tctaaatata
    11821 ccattaacaa cagttattta ttttgctgtt gatctagaca tgttagggga agaaattctt
    11881 gcatatgctg gagaatattt taagggggta tctgctgtaa tgtcatatag cgggtatcaa
    11941 acgggtgttt acggaacaag aaatgtttgt tctcaaataa tcaataacgg gtatgcttcg
    12001 tttgcatttg tttcagatat gtcgactggt tatagtggga atttaggttt tcctatgcct
    12061 agacaatggt cttttgatca atttgttgaa tttaccatag gaagtggcaa cggagctgtt
    12121 ggtatcgatt taatcgctac atcgggtaga gatagcggat ttaatgagtt atcaaatgat
    12181 actaataatg ataattacat tgccaaatac aatcagaagg ttataaatca gatggtacgt
    12241 gcgtatcaat atctatcaca agctggtctt gataatcctt ggaaccctca tttgacattt
    12301 tatagatatg taaattattc tggtttgtca tgggacatca tttcttctcc tgtaacagag
    12361 catgatagaa aaatttatga tgaatatagg aataaattaa ctaatagcga gggcctgtat
    12421 aattatttta tagatcctaa tactggttca ataataggtt tgcctcactt aattgtgacg
    12481 ttacaatcac agatgtttct agccgacaca atcaatgata gtgtttctga ctttgcaggt
    12541 tggttaggag atttaatgac ttgctggggt gaagttaaga aattaggaat acaaatggag
    12601 caaggtgtat ttgcattagt aggtacggct gcaggtggaa catttagtct agaagattta
    12661 taccaagatg ttgacgcggt aaatgtttat accttagcaa aaagaaattc tgattcaaca
    12721 gctttatcgg ctttaaaaac gtactattgt gataagggtg ctattgatag atttaatcaa
    12781 tttgttaaga acagatttgg ttcttcagat aaaatcgctt cagtaacaaa tagtttatta
    12841 gaaaatgacg aaacagttga tatcttaggt gtagggataa tttcattttt cattgataaa
    12901 atagttaata attcacttgg gacagatttt acttatcttg attttattgg agatgagggg
    12961 aaagttgcaa atggattttc tgaaaaaatt attcaatttc aagaaaatag aagtaaactt
    13021 aattaagaat cgtttactat ttaaacagtg tccttttcct ttttaaatat atacgataaa
    13081 ataagtatat gaattgtaaa aggacatgat gattatggaa gaaatagaat ggaataatct
    13141 gactcaaaat aataaaaata attctggatg tggaattatc tttatgtttg ttatagtttt
    13201 gggaatagta gtacttttaa taactgtcaa gatagtagat tactttgcga atactcctga
    13261 agaacaaata cagagaaaac ttcctgagtt tgaaagagta ccaccttatg atccaagaga
    13321 taattcattt caagtaaaaa aattaaaaga gtctccaaat gaaatgtggt ttgaagttac
    13381 agttgaatca agcgacttca aagaaaaaaa gaaagaatac aattatattg taaaggcaaa
    13441 agtatcaaaa agatttattt ttaaccctaa attagaaata tatagtgttg taatagaata
    13501 atagtgttaa aaaaattgta aaagttaaag aagtcaaatt ctgatgtgaa aaataaaata
    13561 taccatggaa gacataaaag aaaaactgga taactagttt atttaatggc agaccgttaa
    13621 ggcctgccat ttttatgtat tttagcggaa taaatataat catgcgggag tgtaaactta
    13681 ctgtttcaaa aagtatactt tttgacatgc cttgattttc tttgtttatg tatggcataa
    13741 taaccacata atacaatttg aaacgtttct gatttaatct gattgttttg aaacaatttt
    13801 agtgaaaaaa gggtagataa aaacgatgag aaaatttttt tatatccggg tcagtagtta
    13861 tgatcaatcg atcgaacgac aactgatttc cgcgaaggaa ttaggaatcc ctgaagaata
    13921 tatatttgta gaaaaagcca gcggcaaaga ttttaaacgc cctgaatatc aattaatgaa
    13981 acggatgttt cgaaaaggag atttactcta tctacaatca ttagatagac taggcagaaa
    14041 taaacaaatg attttagaag aatggcgaga attaactaag gaaaagcaga ttgatatttc
    14101 tgtgttagac atgcctctgt tagatactgc tagttacaag caactagatg ggttagagac
    14161 gcttatctct gacttaattc tgcaattact cagctatatg gccgaagacg agcggaaacg
    14221 aattaatagc cggcaaagag aaggcgtaga agctgcgaaa caaaagggtg taaaattcgg
    14281 cagaaagaaa attgctttac ctcctgaatt tcctgcgatc tattctgact ggaaagcagg
    14341 aaagataact gcagtctatg ctatggatca attgggcatg aaacgaaata ccttttatcg
    14401 acgggtgaaa gaatatgaac ataccttgca ccacttttct tgatagatat aacagctatt
    14461 agacgggaag ggagagtttg aaaatggact taacgaatca aagggtcgtt tttactggaa
    14521 cgctgcagca aatgacacga acccaagcca tcggtttggt tcactcttta aacggccatt
    14581 gtcaatcaag tgttacttca aaaacaaatt tcctggtttg tggtcagtat tctaagtcgt
    14641 tgtttgatga ttctctctat acaaaaaagg aacaaaccgc gcgggacttg attgcgttag
    14701 gtcatgagat taccatttta tcagaagtcg aattttatgc gttaattagt caacagttga
    14761 aagaatggca acggtattta taatcgttag taaaatttac aaggaggaaa atttttatga
    14821 agcgaaaatc ttatgatcgt tggggcattg aaataactag ttttaatcga aatattgctt
    14881 ttcacgtgga gtgtgactgt ggggaattag caaaaagtgt ttatcaaaaa aattactttt
    14941 actgtcctaa atgccatcgc cgatacgggg tacatggaac atagaaacga aatagtgcgg
    15001 tagaaaagcg aatgaatgta gtatatttct acaaatcatt cgctttcttt attttataaa
    15061 tagttggtcg agagatcccg ttttcttttg caatctctgc aactggaatg ccttgcttta
    15121 acatgtccac cacggtttta aaaactaagc gtttttgcgg atctgttgag ttaatagaat
    15181 actcgattgg tcgtccctta tatcggccgg ctttttgagc caataatact ccttgccgct
    15241 gacgttcacg aattttctca cgctcgtttt gtgcaatata acttagcagt gataaaaaca
    15301 tatcgaacat agcggtatcc aggagttcat ttccagtatt aaaatctaaa aactgtgcat
    15361 ctaatatttt taacgctact tttttctgtt tcataaaagc aactgtattt tttatatctt
    15421 cataatctct tcctaaacga tctagtgatg taacgatgac gcaatcacct tcacggatat
    15481 aatttagtaa tttttgaaac tcaggacgct cagtatcttt accactggct ttttcttgga
    15541 ataatttatc aatgttaagt ccttccatca ttgccaattg tcgatccaaa ttttgatctt
    15601 gtgaagatac tcgaatatag ccaatttttc ccataaaaaa ctccttttta aaagtgatat
    15661 aatttacatg taaaatttac ttgtagtttt actgctatca tagcattttt aaaaataaat
    15721 tttatgtaga cttaaaattt acttcatgga gggtttaaat ggatgaaatc aaaagtaaca
    15781 aaaaagcatt tggcatttat ttaggagaac ctagtacaga acaattaaac caattttttt
    15841 atttgcatga aaaagattta gaattgatgg agactatacg acgaccagct actagattag
    15901 gttttgcact acagttagtc tcactacgtt ttttaggaac ttttatatta gatcttacca
    15961 atattcccca aaatgtattg agttatgtag caactcaact aaatattgat cctggagaaa
    16021 ttatctacta tagcaggaga cagaccaggt atcagcacac aaaattgata aaatcacatt
    16081 atggatatca agatttcaac caaccggaaa tagaaacata cctagctaac tggcttttaa
    16141 atagagcgct gtatacaaca gaatcttcag atatgttgtt tgatatgctt ctaaaaaaat
    16201 gtctggatga aaagattgtt ttacctggaa ttactacttt ttctcgtttt gttgctagtg
    16261 caattgaaaa agctgaagag catttatacc gacaattgtc tttggttcca actgaagatg
    16321 agagaaagcg gcttctcaat catttagaat taattggaac tccagtttat ggggcaataa
    16381 tcaaaatgga cattttgaga accccgttag ctgacgatag tcataaagaa atagccagag
    16441 gttttgaccg actaaagcaa tttcaagctt tctctactga aaaatggaag atggaatcta
    16501 ttcctgaagg gaaaataaaa gttcttgcaa attatgcatt taaagctaaa gctcaattaa
    16561 ttcaacgaat gagtgaacag aaaaaactgg cgttgttagt ggcatttatt ttcatataca
    16621 aacgtaaggc tatggatgaa caaattttag cactatctaa tttttttgaa actgttttta
    16681 gacgcgccaa aaataaggaa tctaaagaac gtcttcgtac cataaaagat ctagatcgag
    16741 ccgcatcgac actttcagat attgtagatt tagtaatgtc cagtcattct gatactaatg
    16801 aactatccct tcgcgatcgt atcttagaaa aatattctga ggaaaatgtt accgaagctg
    16861 tatcgcaagt tcggctattg gttaaaaatg atcgtgaacc aatagccatt tctgaacttc
    16921 tgaacactta tcgaaagttc agaaaattta ttccggatat tttaactaca ctaacatttg
    16981 acagcaatga ctacggtaac aactgtaagg aactctggac cttcattaat aatagatttc
    17041 ctaagccgat tacttacaaa atgtttggag ctattaaaca tactcttcca aagaaatgga
    17101 tttattacat tcatgaatac cctgaacaaa ctaataaatg tgtattgatt gcagctgtcg
    17161 aattgttaat tcaatcttta aaacgccatg atatttatat tcctcagagt gtcttatata
    17221 acaatcctat ggattgcttg attgatgaga aaacttgggt tcaacaaaaa tacgttttat
    17281 tagaacaact agatcttcct tcttcagcaa atgaaatgtc tttatggtta aagaacgatt
    17341 tggaactgtc ttataaagaa gcgctaaatc gttggcctac ttctaaaatg gccagaatag
    17401 aaaatgcaga tcgcctggtt gtctctagac ttaaaaagac atatgaaaaa aaggaagata
    17461 agtcttttag acgtcgcatt cagcagttac ttcctaaaat tgatttgtca gatttgttat
    17521 tggaagtaaa ccaacagtta aatcttactc aatcatttaa ccacttaagt gacaaggaca
    17581 ccaaaatgaa agacttggat attagtttat tagcagttct tttatcagag tcctgcaata
    17641 ttggtttttc cccggtttca aaagaaggat ttgattcttt aaagtatgat cgtcttgtct
    17701 atgtcaatca tcattatatt cgagtggata cactttcagg agctaatcaa aaaataatac
    17761 atgcacacag gaaacttgcc acctctaaga tatggggtga tgggcatatg gcttcagctg
    17821 acggtattcg ttatatcaca ccacaacgtt ccctatattc tagaagtaat ccaaaatatt
    17881 ttggccgtgg tcgtgggatc acattctaca attttgtctc tgatcaatat atagggttcc
    17941 acggaatggt cgtttcaggg acactgcgag attcgcttta ccttctagaa ggattcctca
    18001 atcaacccag cgaattaact cctaatcaga tcatgactga tacagctggt tatagcgata
    18061 tgatttttgg tctctttggc ttattagggt ttcaatttag tccaagaatt gccaatgata
    18121 aaggaaccaa actttggcga atcgacgcta acgctcacta cggggaactt gatacgttgt
    18181 ctcaaaattc aattaatatg gaactgattt atacccattg ggaggacatt cttagggttg
    18241 caggttcgtt gaaatctgga aaagtgaatg caacagaatt aacgaaatct cttcaacgga
    18301 atgggcaacc cacgccttta ggaaaagcaa taactgagta tggaaaagtt tataagacga
    18361 aacatcagct tcgttatatt tctgacgaaa tatatgcacg gcaaatttta gaacaattga
    18421 ataaggggga agctcggcat gccttatgcc gtaatatttt ttatggacga aaaggaaaac
    18481 tctaccagac ttattatgat gggatggaag agcagctcaa tgcattagga ttagttacta
    18541 atgccatcat atattggaac tcactgtatt tagaaaaagt atttgaacaa atgaaagctg
    18601 aaggattcga ctgttccgaa gaaatgatac gcaggcaatc tccactaatt agtgatcaca
    18661 tcaattttgt tggtaagtat acgtttagat acgaagctga attatccaac ggtaagttac
    18721 gtccattgaa tgtagaagaa ttctagcaat gttcgggttt tgcatgctac cgcactattt
    18781 cgtatgactg ttccagcgaa tcacttcgaa tagaaaaaga gaaaaacacg agaacagcgt
    18841 taaatcaacg tttcttgtgt ttttactttt gtgctaccgc actatttcgt ttctatgttc
    18901 catgtacccc tttatcaaga agcgcaaaca cgccaaattg ccgattggtt gatcggcatg
    18961 aacgcaagcc ctttatatac cttgaattta caacaaaaag gcgtacaagg tacattttca
    19021 ttaggacgtg tacaaacacc gactttatat ctcatttatc aacgccagga agcaatagaa
    19081 aactttaaaa aagaaccttt tttcctgaat aattcatagt tttactaata gtctttccta
    19141 acattgattt aatagtcttt aaagggttct gttgcaaagt tttaaatcta ctatcaaata
    19201 aggtagaata atagaaaaag atagcaggag gaatgacgat gaatcatttt aaaggaaagc
    19261 aatttcagca ggatgtgatt attgtagccg tgggctacta tcttcgttat aaccttagct
    19321 atcgtgaagt tcaagaaatc ttatatgatc gtggcattaa cgtttctcat acgacgattt
    19381 atcgttgggt gcaagaatat ggcaaactac tctatcaaat tttgatttca aaccattggg
    19441 tcttgcgatt aaagaagccc gtcttagtaa aggattgact cgtgagcagg taggatcaat
    19501 gatccagatt gcgccacgct atttgacgaa cattgaaaat aaaggacaac agccaagttt
    19561 tcatgttgta tatgatttag tgactttgct aaatatttct ttggatggat ttattttagg
    19621 ggaagaaaac agtcataaaa gctccaaacg tcttcaagta gaagcacagt tggattgtct
    19681 ggatgaagat gaattagtga cgattgggaa agtgattcaa gcaatttacg gagaaaaatg
    19741 taaatttaac tagttcaata atacacaatg gattaattaa tactatcagg aaagattgat
    19801 tacaaagatg taatgaattt tttctgattt ttgttaatca taaatagaaa atgaatttat
    19861 ctttgttaca cttaggaact agagcgaatg ataaatagtt ctttggttac tcttatcgct
    19921 gcaaagtaca gttcattttt tgttgttggg aaaattttct ggatttattg catatcactt
    19981 catccgacta aaaatttttg attcccatag cgaagttcgt ttttgttcct taggaaaaac
    20041 ttgactgata tactagtttt gaaatgacga gtaactctgt acttcatcaa taatcaagta
    20101 ttgaatttta attgtatact ttttatgctt gagggatgtc tactgtaata cagctactgc
    20161 aaaaaaaatc agtacactta ttttcttata aaggatatca agaactaagc tcaatggtat
    20221 gcatagaaaa gaaaaagccg ataaaatgag attttgatat ctcgaattat cggctctgcg
    20281 tctttgcgtc tggctctgta attacagtta ttctaaactt cgttatttca attaaaattt
    20341 cttgtctgca tttaggacaa aatagaggga aattttttaa ttcagtatct tccctcattt
    20401 ttaaacgggt cttattgcca catatagggc acagtatcca cctagtattt acaatatcta
    20461 tatcctcctg ttctaattaa caactcaata ttcattttaa aaatttctct ttagttcact
    20521 atcaatgtaa gttgatttta ttaaacatat gccttacttt gtctattcta ttatttggac
    20581 gacgtggttg gaaagcagac ttaatgttag taacctgata accttttaac tctgttaaac
    20641 agacactgcg tccatttgta aagaaagtta aactgtttcg atactcttga atacaacggg
    20701 ctggaatttc accaatgaga atgacctcgt taccttttaa cttagtattt aaaatatttg
    20761 cacaatattt ggaagcatca ttatatgctc tcgaaagata ttcttgtggt acataaattt
    20821 cgaagctaag atatggctct aataactctg taccactctt tctaaaagcc tgctctagta
    20881 caataggcgc aagcattcgg aaatctgctg gcgtactgac agggctgtaa tatagaccat
    20941 acttaaaaca gatcttacag tctgttaatt tccaaccgta caatccttgt tcacacccat
    21001 agcgtatacc ttccataact gcattttgaa atgattgatt taaataacct agagaaacca
    21061 ggctctcata ctgaatgcca ctacccaaag gaagtggtgt tacagataaa ccaatagaag
    21121 cccagaaagg atttggaggt acttcgatat caatggtaaa ttcagatttt tttaatggtc
    21181 tttccatata aatgacagtt ggttttcttg tttctatctc aatatgatat ttttcttgaa
    21241 tcagagtaca agttacctcc atttggacct cacctaaaaa agatagcaca atttcgtgag
    21301 ttactgtatc tacataatat tgtagaaggg gatcactatc ggatatttca aaaagtgcat
    21361 ctagtaactt ttctctttgt actgatttac atggttcaat tgttgtttgt aacataggaa
    21421 gaggattctc aagaatttct ctatgtggta atcttttttt atctccaagt acgttattta
    21481 gttttaaaag ctcatttttt aaaataataa tctcaccagg ctctgcctta tctatctggc
    21541 gtaattctcc atttattgaa gtatacattt ctgtaacttt tattttttcc ttttctgata
    21601 tattgactga gtctcgcaaa tgtagcgttc cactataaag acgtacatag acaagccgtt
    21661 gaccatcatc tgaatattct actttaaaaa catttccaca aagtttatct gaattgagtt
    21721 gtgtgggtga aaataatttg ctagtaatta cctctataag ttgtttaatt ccaatattat
    21781 tctttgcact tccgtgataa acaggatata aggagcaact ttgaattctt tcgttttcct
    21841 ccttttcaag ttctgcaata ttcaatgttt tcccaatggt atatttttct aataaataat
    21901 catttcccac aattactgtc tcccattgtt ctggttcagt ataatctatt acataaggtt
    21961 tcaaatttag attcacagtc tgcttaatta tgatgtcgtc agaaagtttg tccttaatat
    22021 cttgataaac atctggcaaa tttattccat tttgatcaat tttgttaata aaaaatatta
    22081 taggtatgtt catctttcta agtgcatgga atagtatacg agtttgtgac tgtactccat
    22141 cttttgcaga gattagcaaa atagctccat ccaaaacaga taatgaacgg tatacatctg
    22201 ccaaaaaatc catgtgtcca ggagtatcta caatatttac tttaacattt tcccgttgaa
    22261 aagatgttat tgcggtctga atagtaatac ctctctggcg ttccaaaaac atagtatccg
    22321 ttttcgttgt accgctatct acacttccta actctttaat tgctccgcta ctgtatagta
    22381 agctttctgt caaagtagtt tttcctgcat caacatgtgc taagataccg atattaataa
    22441 ttttcaattt tatttcctcc attcaaaagc tcaaaaagca gaaaaaatcc cagtgataaa
    22501 tactcttatc actgggattt taatacaaaa atagctgtat actacacact gatagccaca
    22561 gatgctttat gataaaatga taaaagtatt cttaaactgg gcacaaaaaa ccagtcctta
    22621 ttttaaataa ggatgcttaa ttaattattc ccgctatcta attgacagtt tatttaagaa
    22681 taccttgccg catttttatt atctcctttt gaatgttatc ttaattctat catatgatag
    22741 aatgcttgta aagccaacca tattttttga acgaaaggga aattaatgag aaattaatgg
    22801 aagttagtgt agtagttgaa gataactctt cagaatggct atcaaaattc agcgatttaa
    22861 taacgattta caagttcata agggattctt tattcatcca gctattatat tacttttcag
    22921 gtcaatagga caactgtcca caacctttct acaaatatat tacgtataat ttttgaaata
    22981 tatactgctt aacaaaatat tttgcagtgg ttccaatagt tttgaattgt taatattaag
    23041 tttgacttgg aaaatatcat taaaagggtt ctgttgcaaa gttttaaatc tactatcaaa
    23101 taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt ttaaaggaaa
    23161 gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt ataaccttag
    23221 ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc atacgacgat
    23281 ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa agaaaaataa
    23341 aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag gaaaatggca
    23401 ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt tacgtaaaaa
    23461 acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt ttgatgaacc
    23521 gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga aactaaaaga
    23581 atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata atttgattga
    23641 acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac gcactgcctc
    23701 taccacgatt aaaggcatgg aagccattcg aggattatat aagaaaaccc gaaaagaagg
    23761 cactctcttc gggttttcgg tctgtactga aatcaaggta ttattgggaa tcccagctta
    23821 aatcatagat accgtaaggg attttattct ttatttaaaa ctttgcaaca gaaccaacta
    23881 gactgtgcaa aatagagaca cttgaaaaat ctatcggggg tcagaaactt aatagttttt
    23941 gacacataaa caaaatcgcg atataatggg gttgagagtg tttcataaac ttatgtcata
    24001 aagttaagga gatttcgcat gattttagag aataaattgg gattaaccaa tcaagttgag
    24061 ttggctaagg ttgaagaaaa actcagtaaa caaaaagcga aagaattgta cgattgtgga
    24121 aaaataaatg aaatcgaagt tggtacattt aaaggtttat ctgaaattca tgaatttcta
    24181 ttttcggata tttacgattt tgccggaaaa atccgatcgg tcaatattgc aaaaggaaat
    24241 tttcgatttg caccagttat gtatttagaa cattcgttac agcatattga tcagatgcca
    24301 caaacttctt ttgaagagat tatcaagaaa tatgtggaga tgaatatcgc tcacccattt
    24361 cgagaaggaa atggccgaag tactagaatt tggctggatc tcattttaaa ggaagaattg
    24421 caaaaagttg tagattggaa cttaatcgat aaagcagact atctttctgc aatggagcga
    24481 agtcccataa acgatttgga aatacgctat ctaatttcca atgctctgac tgataaaatt
    24541 gacgatcgcg agttatatat gaaaggaatc gatgtcagct atttctatga agggtattct
    24601 gagtatacga tagatgattt gtaaaagtag gtggaccaaa tgacgaaata tggatatgca
    24661 cgtgtctcaa ccgcttctca aagtacaaaa gaacaaattc aacagttgct tgagaacggc
    24721 gtagagaaga agaatatttt ttcagaaaaa tttacgggta caaaacggga tcggccaaaa
    24781 ttcaatcagc tgttggctgg tctgaagcct ggagatgaaa tagttgttac gaagcttgat
    24841 cgatttgctc gtaacacgag agaagcatta gagatcattg aacctttact cgatgataac
    24901 gtaacgatca aggttttgaa tctaggaacg attgaaaata cgtccatggg gcgaatggtg
    24961 acacggacgt tgttgagtgt agcagaaatg gaacgtgata tgattgtgga acgtacccaa
    25021 gaaggaaaaa tgtttgcaag aaagaataat cctaatttca gagaaggacg tccgaaagca
    25081 acaatcacac cgaagaagag gcacgcatat gaactgctta cttcaggtaa atcgtataag
    25141 gaagttgaag ctataaccgg tttcagtcgc agtacgcttt ttagaataaa gaagaaaatt
    25201 gaagaaagtt aaaaaagaag tctcagcgaa ccagacaggt aaatacttaa tgcgttctag
    25261 atatgagtct attagcatgt tgtgaaatat aatatttttt tatttacttg atttctgctc
    25321 aaaaaatgtg tatggtaact gtaaaaggta aagtaattaa aggtatgcta gccacgctta
    25381 ctatattagg ataccatcat atatttataa tgaacgattt gttcgtctac caaacaacac
    25441 atatcgttca gcgtaagtca cgtttaggaa cgtggctttt ttagtgttat tatcgataaa
    25501 taatctattg actctattga ttttatctcc atatccctac ggtgttgatt gtctttagat
    25561 ctttcattta agaaccaaat aactatcata aaaatcagca ctgctgctaa tataataaac
    25621 agcattccta ttgtgatatt actggatttg agtcaatatc ttggacacat tttagtagag
    25681 acggttaagc cattttttct tttgctaatt cttcaaattc ctgtggggtt agatagtgaa
    25741 tcgagctatg gattcgattt cggttataaa atccttcaat gtagctaaat agcgctcgat
    25801 ttgcttcttc aaaatctgag tagctagtcg tgtagacttc ttcttttttc aatgaggcat
    25861 ggaaagattc gattccagca ttatcataag gtgttccttt tctactataa gaatgcctta
    25921 ttttgttggt tttaagccat tgttccactt ctcttgctgt gtattggctg cccaagtcag
    25981 tgtgtagaat cattccttct ggaatgtgat aatgtatttt tgctttattc aatgtttgaa
    26041 tgacacaatc cacagtcatt cgttttgaaa atgtataact aataattctt ttcgtgtgta
    26101 aatccatgat tgaagataag taacaccaac catttttctt agtaggaatg tacgtaatgt
    26161 cagctgccca tttctcacag atcgtttcag tagaaaagtc ctgatttaag agattctctt
    26221 ttgaaatgat ggaatggcaa cagttttttt gacaaatttt ataaggtgca gaacttcttt
    26281 ccgtatgcta ttccgattgt ccttgacaat gagcctcctc ggatgtgacg atcttcggca
    26341 ggagctaaca gttaaagtta gactgcctcg ctagcgttag cacatccgag ctcattatca
    26401 aggattcgct gcgccaatct ctggttacgg taaccaaccg gtgtctcgta gccaagtgta
    26461 ccgtgcaacc gaaggtggtt ccaccaattg acatagtcaa ataactccaa atccaattgt
    26521 tgtaaggttt caaatgtgta ttgatagaca aattctactt tcaacgactt ataagttgat
    26581 tcagctacgg cattatcaaa aggacagcct ttatgactca atgatcgatt gatgtcaaaa
    26641 gttgttaata attcatcaat agcttggtta tcaaactctt ttccacgatc agtatgaaaa
    26701 atctcaacct ctgtcagagg ttgtttgata cggctaaatg ctttttttac tagaacggca
    26761 tctttatgtt ctccacaaga atagccgaga atttctcgat tgaacagatc caaaatgaaa
    26821 cagacataat tccatttttt cccgactcgt acataagtca agtctgttac gatcgcttct
    26881 aatgggttgt ctcttaagaa tttacgattc aatacgtttg tcgttttggc ttcattgcaa
    26941 gtagaatgat gtactttaaa ataagcaaca gtatagctcg attttaatcc tctatttttc
    27001 atgattctac taatttttcg tcggctgatc tgaatgcctc gttttgataa ggcttttttt
    27061 atttttcttg agccgtaggc ctttcggctg cggataaatt cttcagcgac tacttcttca
    27121 agttctgatt cgtctttctt tggttttgat tgataataat aggactgacg tgatagacct
    27181 aatattctgc a
//
