LOCUS       NZ_CP058746            36029 bp    DNA     circular CON 30-APR-2024
DEFINITION  Klebsiella pneumoniae strain STLIN_10 plasmid unnamed3, complete
            sequence.
ACCESSION   NZ_CP058746
VERSION     NZ_CP058746.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN13925567
            Assembly: GCF_022494255.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 36029)
  AUTHORS   Che,Y., Xu,X., Yang,Y., Brinda,K., Hanage,W., Yang,C. and Zhang,T.
  TITLE     High-resolution genomic surveillance elucidates a multilayered
            hierarchical transfer of resistance between WWTP- and
            human/animal-associated bacteria
  JOURNAL   Microbiome 10 (1), 16 (2022)
   PUBMED   35078531
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36029)
  AUTHORS   Che,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2020) Civil Engineering, The University of Hong
            Kong, Pokfulam Road, Hong Kong 000000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. Unicycler 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology :: Illumina; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022494255.1-RS_2024_04_30
            Annotation Date                   :: 04/30/2024 04:30:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,530
            CDSs (total)                      :: 5,408
            Genes (coding)                    :: 5,263
            CDSs (with protein)               :: 5,263
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 56 of 145
            Pseudo Genes (incomplete)         :: 96 of 145
            Pseudo Genes (internal stop)      :: 22 of 145
            Pseudo Genes (multiple problems)  :: 27 of 145
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP058746.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..36029
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="STLIN_10"
                     /isolation_source="Stanley WWTPs_10 WWTPs influent"
                     /db_xref="taxon:573"
                     /plasmid="unnamed3"
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.2 N 114.2 E"
                     /collection_date="2018-12"
     gene            join(35830..36029,1..640)
                     /gene="sul1"
                     /locus_tag="HZS96_RS27365"
                     /old_locus_tag="HZS96_27245"
     ARG             3..640
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide resistant sul"
                     /tool="rgi"
                     /drug_class="sulfonamide antibiotic"
                     /identity="100.0"
                     /coverage="75.99"
     gene            1045..2586
                     /locus_tag="HZS96_RS27370"
                     /old_locus_tag="HZS96_27250"
     CDS             1045..2586
                     /locus_tag="HZS96_RS27370"
                     /old_locus_tag="HZS96_27250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000050481.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91-like element ISCR1 family transposase"
                     /protein_id="WP_000050481.1"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASLE
                     AQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGARRM
                     AESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIKKAG
                     YTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYDELNT
                     LAHTLSHRIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGPQQGRK
                     VFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPAVSEKRL
                     ALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVFAPNSKHR
                     VQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVCEHCGGHVK
                     VIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQSRLFD"
                     /name="IS91-like element ISCR1 family transposase"
     gene            complement(<2819..3358)
                     /locus_tag="HZS96_RS27375"
                     /old_locus_tag="HZS96_27255"
                     /pseudo=""
     CDS             complement(<2819..3358)
                     /locus_tag="HZS96_RS27375"
                     /old_locus_tag="HZS96_27255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460650.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /name="ABC transporter substrate-binding protein"
     gene            3893..4345
                     /locus_tag="HZS96_RS27380"
                     /old_locus_tag="HZS96_27260"
     CDS             3893..4345
                     /locus_tag="HZS96_RS27380"
                     /old_locus_tag="HZS96_27260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgcJ/EcaC family oxidoreductase"
                     /protein_id="WP_003833285.1"
                     /translation="MNKLLSLVVSLALLPGAVFAASTPDCVKVNKAQIEALFDKWNESL
                     KTGNAQTVSENYLSDAVLLPTVSNKARLTDAERVDYFEHFLAKKPTGKIDMRTIRLGCN
                     KAIDTGTYTFTFADKSTVSARYTFTYAWDGKEWKISTHHSSAMPEG"
                     /name="SgcJ/EcaC family oxidoreductase"
     gene            complement(4387..5031)
                     /locus_tag="HZS96_RS27385"
                     /old_locus_tag="HZS96_27265"
     CDS             complement(4387..5031)
                     /locus_tag="HZS96_RS27385"
                     /old_locus_tag="HZS96_27265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017900990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrB91"
                     /protein_id="WP_065908739.1"
                     /translation="MALALVGEKINRNRFTGEKIENSTFFNCDFSGADLSGTEFIGCQF
                     YDRESQKGCNFSRAMLKDAIFKSCDLSMADFRNASALGIEICHCRAQGADFRGASFMNM
                     ITTRTWFCSAYITNTNLSYANFSKVVLEKCELWENRWMGAQVLGATFSGSDLSGGEFST
                     FDWRAANFTHCDLTNSELGDLDIRRVDLQGVKLDNYQASLLMERLGIAIIG"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrB91"
     gene            complement(5127..>5333)
                     /locus_tag="HZS96_RS27390"
                     /old_locus_tag="HZS96_27270"
                     /pseudo=""
     CDS             complement(5127..>5333)
                     /locus_tag="HZS96_RS27390"
                     /old_locus_tag="HZS96_27270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003833280.1"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /name="helix-turn-helix domain-containing protein"
     gene            <5325..5528
                     /locus_tag="HZS96_RS27395"
                     /old_locus_tag="HZS96_27275"
                     /pseudo=""
     CDS             <5325..5528
                     /locus_tag="HZS96_RS27395"
                     /old_locus_tag="HZS96_27275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA];
                     GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="SMR family transporter"
                     /name="SMR family transporter"
     ARG             35831..36027
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide resistant sul"
                     /tool="rgi"
                     /drug_class="sulfonamide antibiotic"
                     /identity="100.0"
                     /coverage="23.66"
     ARG             5523..6358
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            6489..6989
                     /locus_tag="HZS96_RS27405"
                     /old_locus_tag="HZS96_27285"
     CDS             6489..6989
                     /locus_tag="HZS96_RS27405"
                     /old_locus_tag="HZS96_27285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194535.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000376623.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARID
                     RTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHAGR
                     GVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAERLE
                     LEI"
                     /name="GNAT family N-acetyltransferase"
     gene            <7310..7378
                     /locus_tag="HZS96_RS27410"
                     /old_locus_tag="HZS96_27290"
                     /pseudo=""
     CDS             <7310..7378
                     /locus_tag="HZS96_RS27410"
                     /old_locus_tag="HZS96_27290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /name="EAL domain-containing protein"
     gene            7496..8260
                     /locus_tag="HZS96_RS27415"
                     /old_locus_tag="HZS96_27295"
     CDS             7496..8260
                     /locus_tag="HZS96_RS27415"
                     /old_locus_tag="HZS96_27295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389365.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /protein_id="WP_001389365.1"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDHT
                     TIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTIDFY
                     LSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETAHRQ
                     VKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQPGIR
                     GEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
                     /name="IS6-like element IS6100 family transposase"
     gene            complement(8753..9337)
                     /gene="mphR(A)"
                     /locus_tag="HZS96_RS27420"
                     /old_locus_tag="HZS96_27300"
     CDS             complement(8753..9337)
                     /gene="mphR(A)"
                     /locus_tag="HZS96_RS27420"
                     /old_locus_tag="HZS96_27300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide-binding transcriptional repressor
                     MphR(A)"
                     /protein_id="WP_001137892.1"
                     /translation="MPRPKLKSDDEVLEAATVVLKRCGPIEFTLSGVAKEVGLSRAALI
                     QRFTNRDTLLVRMMERGVEQVRHYLNAIPIGAGPQGLWEFLQVLVRSMNTRNDFSVNYL
                     ISWYELQVPELRTLAIQRNRAVVEGIRKRLPPGAPAAAELLLHSVIAGATMQWAVDPDG
                     ELADHVLAQIAAILCLMFPEHDDFQLLQAHA"
                     /name="mphR(A)"
     gene            complement(9337..10575)
                     /gene="mrx(A)"
                     /locus_tag="HZS96_RS27425"
                     /old_locus_tag="HZS96_27305"
                     /gene_synonym="mrx"
     CDS             complement(9337..10575)
                     /gene="mrx(A)"
                     /locus_tag="HZS96_RS27425"
                     /old_locus_tag="HZS96_27305"
                     /gene_synonym="mrx"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide resistance MFS transporter Mrx(A)"
                     /protein_id="WP_000004159.1"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWAG
                     ATAASSVIATIIGAWVGGGLVDRFGRAPVALISGVVGGVAMASIPLLDAVGALSNTGLI
                     ACVVLGAAFDAPGMAAQDSELPKLGHVAGLSVERVSSLKAVIGNVAILGGPALGGAAIG
                     LLGAAPTLGLTAFCSVLAGLLGAWVLPARAARTMTTTATLSMRAGVAFLWSEPLLRPLF
                     GIVMIFVGIVGANGSVIMPALFVDAGRQVAELGLFSSMMGAGGLLGIAIHASVGARISA
                     QNWLAVAFCGSAVGSLLLSQLPGVPVLMLLGALVGLLTGSVSPILNAAIYNRTPPELLG
                     RVLGTVSAVMLSASPMVMLAAGAFVDLAGPLPGLVVSAVFAGLVALLSLRLQFATMAAA
                     ATASAPTHTEGEH"
                     /name="mrx(A)"
     gene            complement(10572..11477)
                     /locus_tag="HZS96_RS27430"
                     /old_locus_tag="HZS96_27310"
     CDS             complement(10572..11477)
                     /locus_tag="HZS96_RS27430"
                     /old_locus_tag="HZS96_27310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000219391.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDD
                     GRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMV
                     IQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDV
                     DRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSE
                     ARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFA
                     LDSGNEEYLAAAKAQLAAAE"
                     /name="Mph(A) family macrolide 2'-phosphotransferase"
     gene            complement(11599..12303)
                     /locus_tag="HZS96_RS27435"
                     /old_locus_tag="HZS96_27315"
     CDS             complement(11599..12303)
                     /locus_tag="HZS96_RS27435"
                     /old_locus_tag="HZS96_27315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <12368..12622
                     /locus_tag="HZS96_RS27440"
                     /old_locus_tag="HZS96_27320"
                     /pseudo=""
     CDS             <12368..12622
                     /locus_tag="HZS96_RS27440"
                     /old_locus_tag="HZS96_27320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            12680..12922
                     /locus_tag="HZS96_RS27445"
                     /old_locus_tag="HZS96_27325"
     CDS             12680..12922
                     /locus_tag="HZS96_RS27445"
                     /old_locus_tag="HZS96_27325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000844627.1"
                     /translation="MKTAALDLARERQAHEAGARTRATAHERTPQQERQKAAREAERGR
                     EAWTLGQGMKKPVAGCYGRLTRWKGGGDVVYMALL"
                     /name="transposase"
     gene            complement(12954..13604)
                     /gene="tetR(A)"
                     /locus_tag="HZS96_RS27450"
                     /old_locus_tag="HZS96_27330"
     CDS             complement(12954..13604)
                     /gene="tetR(A)"
                     /locus_tag="HZS96_RS27450"
                     /old_locus_tag="HZS96_27330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /protein_id="WP_000164043.1"
                     /translation="MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHF
                     RNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHAGTR
                     PGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGDSDAGERGGTVE
                     QAPLSPLLRAAIDAFDEAGPDAAFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD"
                     /name="tetR(A)"
     gene            13710..14909
                     /gene="tet(A)"
                     /locus_tag="HZS96_RS27455"
                     /old_locus_tag="HZS96_27335"
     ARG             13711..14906
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(<14876..15064)
                     /locus_tag="HZS96_RS27460"
                     /old_locus_tag="HZS96_27340"
                     /pseudo=""
     CDS             complement(<14876..15064)
                     /locus_tag="HZS96_RS27460"
                     /old_locus_tag="HZS96_27340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /name="IS91 family transposase"
     gene            complement(15176..15481)
                     /locus_tag="HZS96_RS27465"
                     /old_locus_tag="HZS96_27345"
     CDS             complement(15176..15481)
                     /locus_tag="HZS96_RS27465"
                     /old_locus_tag="HZS96_27345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_001255015.1"
                     /translation="MRRTNHRNLVNVGILSGRIPLISLVQFIAVAEHLNFRHAAKALGI
                     SQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAVKTAE"
                     /name="LysR family transcriptional regulator"
     gene            complement(15509..16723)
                     /gene="floR"
                     /locus_tag="HZS96_RS27470"
                     /old_locus_tag="HZS96_27350"
     ARG             complement(15513..16723)
                     /name="floR"
                     /gene="floR"
                     /gene_name="chloramphenicol/florfenicol efflux MFS
                     transporter FloR"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(16940..17668)
                     /locus_tag="HZS96_RS27475"
                     /old_locus_tag="HZS96_27355"
     CDS             complement(16940..17668)
                     /locus_tag="HZS96_RS27475"
                     /old_locus_tag="HZS96_27355"
                     /inference="COORDINATES: protein motif:HMM:NF023271.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3363 domain-containing protein"
                     /protein_id="WP_094545105.1"
                     /translation="MSFRSTERQTPYSSYTCRVPGGDYEGYVDAHVRRLEALRRAGIVE
                     RIDADQWRIPDDLVSRAAAHDAGRDSQASVRVLSPVDLNKQIGSDGATWLDRRLIHGET
                     ADLAPTGFGQQVREAMDQRREHHIEQGDATRSRDSRVFYRRNLLAILREREVAGVGSDM
                     ALSKGLPFRAATDGESVSGKFTGTVHLSSGKFAVVEKSHEFTLVPWRPIIDRQLGREVM
                     GIVQGGSVSWQLGRQRGLER"
                     /name="DUF3363 domain-containing protein"
     gene            complement(17670..20675)
                     /locus_tag="HZS96_RS27480"
                     /old_locus_tag="HZS96_27360"
     CDS             complement(17670..20675)
                     /locus_tag="HZS96_RS27480"
                     /old_locus_tag="HZS96_27360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143759.1"
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            20839..21396
                     /locus_tag="HZS96_RS27485"
                     /old_locus_tag="HZS96_27365"
     CDS             20839..21396
                     /locus_tag="HZS96_RS27485"
                     /old_locus_tag="HZS96_27365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001235713.1"
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            21579..22439
                     /locus_tag="HZS96_RS27490"
                     /old_locus_tag="HZS96_27370"
     CDS             21579..22439
                     /locus_tag="HZS96_RS27490"
                     /old_locus_tag="HZS96_27370"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     gene            22698..23174
                     /locus_tag="HZS96_RS27495"
                     /old_locus_tag="HZS96_27375"
     CDS             22698..23174
                     /locus_tag="HZS96_RS27495"
                     /old_locus_tag="HZS96_27375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016943399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /protein_id="WP_013023839.1"
                     /translation="MKQITMSDMQQQSAAAVQSPRLRAHRNFHPELSDSVQRLAIAMEP
                     GTYVRPHRHPHTFELLLPLRGRFVVLNFDDRGTVTHRAILGETCTVLEMAAGTWHAVLS
                     LDTGGIIFEVKHGGYQPVAADDYAHWAPAEGEPGTTELMAWYAQAQVGDSTFAV"
                     /name="WbuC family cupin fold metalloprotein"
     gene            complement(23221..24096)
                     /locus_tag="HZS96_RS27500"
                     /old_locus_tag="HZS96_27380"
     CDS             complement(23221..24096)
                     /locus_tag="HZS96_RS27500"
                     /old_locus_tag="HZS96_27380"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extended-spectrum class A beta-lactamase CTX-M-3"
                     /protein_id="WP_011091028.1"
                     /translation="MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQSG
                     GRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSD
                     LVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETF
                     RLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAA
                     SIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESRRDVLA
                     SAAKIVTDGL"
                     /name="extended-spectrum class A beta-lactamase CTX-M-3"
     gene            complement(24431..>24625)
                     /locus_tag="HZS96_RS27505"
                     /old_locus_tag="HZS96_27385"
                     /pseudo=""
     CDS             complement(24431..>24625)
                     /locus_tag="HZS96_RS27505"
                     /old_locus_tag="HZS96_27385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            24682..25379
                     /locus_tag="HZS96_RS27510"
                     /old_locus_tag="HZS96_27390"
     CDS             join(24682..24931,24931..25379)
                     /locus_tag="HZS96_RS27510"
                     /old_locus_tag="HZS96_27390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558270.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="WP_223216367.1"
                     /translation="MASISISCPSCSATEGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLSLLSAFEVVVW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1 family transposase"
     gene            complement(<25395..26300)
                     /locus_tag="HZS96_RS27515"
                     /old_locus_tag="HZS96_27395"
                     /pseudo=""
     CDS             complement(<25395..26300)
                     /locus_tag="HZS96_RS27515"
                     /old_locus_tag="HZS96_27395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEcp1 family transposase"
                     /name="IS1380-like element ISEcp1 family transposase"
     gene            26650..27510
                     /gene="aac(3)-IId"
                     /locus_tag="HZS96_RS27520"
                     /old_locus_tag="HZS96_27400"
     ARG             26651..27507
                     /name="aac(3)-IId"
                     /gene="aac(3)-IId"
                     /gene_name="aminoglycoside N-acetyltransferase AAC(3)-IId"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            27523..>27816
                     /locus_tag="HZS96_RS27525"
                     /old_locus_tag="HZS96_27405"
                     /pseudo=""
     CDS             27523..>27816
                     /locus_tag="HZS96_RS27525"
                     /old_locus_tag="HZS96_27405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="tunicamycin resistance protein"
                     /name="tunicamycin resistance protein"
     gene            27879..>28232
                     /locus_tag="HZS96_RS27530"
                     /old_locus_tag="HZS96_27410"
                     /pseudo=""
     CDS             27879..>28232
                     /locus_tag="HZS96_RS27530"
                     /old_locus_tag="HZS96_27410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /name="IS6-like element IS26 family transposase"
     gene            28297..29001
                     /locus_tag="HZS96_RS27535"
                     /old_locus_tag="HZS96_27415"
     CDS             28297..29001
                     /locus_tag="HZS96_RS27535"
                     /old_locus_tag="HZS96_27415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(29191..30006)
                     /locus_tag="HZS96_RS27540"
                     /old_locus_tag="HZS96_27420"
     CDS             complement(29191..30006)
                     /locus_tag="HZS96_RS27540"
                     /old_locus_tag="HZS96_27420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3')-Ia"
                     /protein_id="WP_000018329.1"
                     /translation="MSHIQRETSCSRPRLNSNMDADLYGYKWARDNVGQSGATIYRLYG
                     KPDAPELFLKHGKGSVANDVTDEMVRLNWLTEFMPLPTIKHFIRTPDDAWLLTTAIPGK
                     TAFQVLEEYPDSGENIVDALAVFLRRLHSIPVCNCPFNSDRVFRLAQAQSRMNNGLVDA
                     SDFDDERNGWPVEQVWKEMHKLLPFSPDSVVTHGDFSLDNLIFDEGKLIGCIDVGRVGI
                     ADRYQDLAILWNCLGEFSPSLQKRLFQKYGIDNPDMNKLQFHLMLDEFF"
                     /name="aminoglycoside O-phosphotransferase APH(3')-Ia"
     gene            30157..30861
                     /locus_tag="HZS96_RS27545"
                     /old_locus_tag="HZS96_27425"
     CDS             30157..30861
                     /locus_tag="HZS96_RS27545"
                     /old_locus_tag="HZS96_27425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(31332..32345)
                     /gene="intI1"
                     /locus_tag="HZS96_RS27550"
                     /old_locus_tag="HZS96_27430"
     CDS             complement(31332..32345)
                     /gene="intI1"
                     /locus_tag="HZS96_RS27550"
                     /old_locus_tag="HZS96_27430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="WP_000845048.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFI
                     RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI
                     GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG
                     TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR
                     AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH
                     SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER"
                     /name="intI1"
     gene            32637..33191
                     /locus_tag="HZS96_RS27555"
                     /old_locus_tag="HZS96_27435"
     CDS             32637..33191
                     /locus_tag="HZS96_RS27555"
                     /old_locus_tag="HZS96_27435"
                     /EC_number="2.3.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoroquinolone-acetylating aminoglycoside
                     6'-N-acetyltransferase AAC(6')-Ib-cr5"
                     /protein_id="WP_063840321.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLAD
                     VQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGRWEEETDPGVRGIDQLLA
                     NASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTVTTP
                     YGPAVYMVQTRQAFERTRSDA"
                     /name="fluoroquinolone-acetylating aminoglycoside
                     6'-N-acetyltransferase AAC(6')-Ib-cr5"
     gene            33288..33740
                     /locus_tag="HZS96_RS27560"
                     /old_locus_tag="HZS96_27440"
     CDS             33288..33740
                     /locus_tag="HZS96_RS27560"
                     /old_locus_tag="HZS96_27440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)--rifampin ADP-ribosyltransferase Arr-3"
                     /protein_id="WP_001749986.1"
                     /translation="MVKDWIPISHDNYKQVQGPFYHGTKANLAIGDLLTTGFISHFEDG
                     RILKHIYFSALMEPAVWGAELAMSLSGLEGRGYIYIVEPTGPFEDDPNLTNKRFPGNPT
                     QSYRTCEPLRIVGVVEDWEGHPVELIRGMLDSLEDLKRRGLHVIED"
                     /name="NAD(+)--rifampin ADP-ribosyltransferase Arr-3"
     gene            33873..34346
                     /gene="dfrA27"
                     /locus_tag="HZS96_RS27565"
                     /old_locus_tag="HZS96_27445"
     ARG             33874..34343
                     /name="dfrA27"
                     /gene="dfrA27"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA27"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            34527..35372
                     /locus_tag="HZS96_RS27570"
                     /old_locus_tag="HZS96_27450"
     CDS             34527..35372
                     /locus_tag="HZS96_RS27570"
                     /old_locus_tag="HZS96_27450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_048608579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA16"
                     /protein_id="WP_001749984.1"
                     /translation="MSNAVPAEISVQLSQALNVIEHHLGSTLLAVHLYGSALDGGLKPC
                     SDIDLLVTVTAQLDETVRQALFVDFLEVSASPGQSEALRALEVTIVVYGDVVPWRYPAR
                     RELQFGEWQRKDILAGIFEPATTDVDLAILLTKARQHSLALAGSAAEDFFNSVPESDLF
                     KALADTLKLWNSQPDWAGDERNVVLTLSRIWYSAATGKIAPKDVAANWVMERLPVQHQP
                     VLLEAQQAYLGQGMDCLASRADQLTAFIYFVKHEAASLLGSTPMMSNSSFKPTPLRGAA
                     "
                     /name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA16"
     gene            35489..35836
                     /locus_tag="HZS96_RS27575"
                     /old_locus_tag="HZS96_27455"
     CDS             35489..35836
                     /locus_tag="HZS96_RS27575"
                     /old_locus_tag="HZS96_27455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="WP_000679427.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY
                     FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSP
                     SWKSLRRPTPW"
                     /name="quaternary ammonium compound efflux SMR transporter
                     QacE delta 1"
     ARG             complement(4391..5031)
                     /name="qnrB91"
                     /gene="qnrB91"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrB91"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             35490..35833
                     /name="qacEdelta1"
                     /gene="qacEdelta1"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(10576..11477)
                     /name="mph(A)"
                     /gene="mph(A)"
                     /gene_name="Mph(A) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             33289..33737
                     /name="arr-3"
                     /gene="arr-3"
                     /gene_name="NAD(+)--rifampin ADP-ribosyltransferase Arr-3"
                     /tool="amrfinderplus"
                     /drug_class="RIFAMYCIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(23225..24096)
                     /name="blaCTX-M-3"
                     /gene="blaCTX-M-3"
                     /gene_name="extended-spectrum class A beta-lactamase
                     CTX-M-3"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             34528..35369
                     /name="aadA16"
                     /gene="aadA16"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA16"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             32638..33188
                     /name="aac(6')-Ib-cr5"
                     /gene="aac(6')-Ib-cr5"
                     /gene_name="fluoroquinolone-acetylating aminoglycoside
                     6'-N-acetyltransferase AAC(6')-Ib-cr5"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE/QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(29195..30006)
                     /name="aph(3')-Ia"
                     /gene="aph(3')-Ia"
                     /gene_name="aminoglycoside O-phosphotransferase APH(3')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21580..22436
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(10573..11477)
                     /name="mphA"
                     /gene="mphA"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             32593..33191
                     /name="AAC(6')-Ib-cr6"
                     /gene="AAC(6')-Ib-cr6"
                     /gene_name="AAC(6'); AAC(6')-Ib-cr"
                     /tool="rgi"
                     /drug_class="fluoroquinolone antibiotic; aminoglycoside
                     antibiotic"
                     /identity="98.99"
                     /coverage="100.0"
     ARG             complement(4388..5031)
                     /name="QnrB2"
                     /gene="QnrB2"
                     /gene_name="quinolone resistance protein (qnr)"
                     /tool="rgi"
                     /drug_class="fluoroquinolone antibiotic"
                     /identity="99.53"
                     /coverage="100.0"
     ARG             complement(9338..10575)
                     /name="Mrx"
                     /gene="Mrx"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
ORIGIN
        1 gctcttagac gccctgtccg atcagatgca ccgtgtttca atcgacagct tccaaccgga
       61 aacccagcgc tatgcgctca agcgcggcgt gggctacctg aacgatatcc aaggatttcc
      121 tgaccctgcg ctctatcccg atattgctga ggcggactgc aggctggtgg ttatgcactc
      181 agcgcagcgg gatggcatcg ccacccgcac cggtcacctt cgacccgaag acgcgctcga
      241 cgagattgtg cggttcttcg aggcgcgggt ttccgccttg cgacggagcg gggtcgctgc
      301 cgaccggctc atcctcgatc cggggatggg atttttcttg agccccgcac cggaaacatc
      361 gctgcacgtg ctgtcgaacc ttcaaaagct gaagtcggcg ttggggcttc cgctattggt
      421 ctcggtgtcg cggaaatcct tcttgggcgc caccgttggc cttcctgtaa aggatctggg
      481 tccagcgagc cttgcggcgg aacttcacgc gatcggcaat ggcgctgact acgtccgcac
      541 ccacgcgcct ggagatctgc gaagcgcaat caccttctcg gaaaccctcg cgaaatttcg
      601 cagtcgcgac gccagagacc gagggttaga tcatgcctag cattcacctt ccggccgccc
      661 gctaaatatc tccttttggg ttgttaataa aacatccaat aagttgactg tgcgtgaaaa
      721 agaaagtttt gtgtgatggc gttgaagatc gcaccgttaa gctcttatgt gggatggtgc
      781 agagctcgac gactaccgat aaaacgcaac cgccgcaaac agacaagaaa aagccccaac
      841 tgataacagt tggggcttca gtattgtgat tggtggagca atagcaccct gaacccaaaa
      901 ccttctcgct caaccggtag tggctgataa caactcgtga gggctattgc gggttaagca
      961 tttagcgatg tctagggcca gactggacgt ctgaacgcaa gccgctgata ctgtacataa
     1021 ccacagtatc agcggaggat acccatgtcg ctggcaagga acgccacggc gagtcaatcg
     1081 cccactcaaa caaacggtta cgaacgccac caacccgacc agacgctgct ctaccagctg
     1141 gttgagcagc actacccagc cttcaaagcc tcactcgaag cccaaggtca acacctgcct
     1201 cgctacatcc aacaagaatt caacgacctc ctccaatgtg gccgtctgga gtatggtttc
     1261 atgcgggttc gctgcgagga ttgtcatcac gagcgtctgg tcgccttcag ctgtaaacga
     1321 cgcggctttt gccctagctg cggtgcccgc cggatggccg agagtgcggc gctgctgata
     1381 gacgaagtct tccccaagga gcccattcgc cagtgggtgc tcagctttcc tttccagcta
     1441 cgctttttgc tggctcgcca tccccagctg atgggccagg tcttgagtat cgtctatcgt
     1501 acactctcaa ctcatctgat caaaaaagcc ggttacacca aagcctctgc acaaactggc
     1561 tcagtgactc ttatccaacg ctttggctcc gcgctaaatc tcaatgtcca ctaccacatg
     1621 ctgtttctcg atggtgtcta tgccgaagat gactatggca agcaacgctt ccatcgtgtc
     1681 aaggcaccca cttacgatga gctgaatacg ctcgctcaca ccctcagcca tcgcatcgct
     1741 cgctgcatgg aaaagcgtgg gattttggag cgtgatgccg agaatacgtg gttgacactg
     1801 gaagagggcg aagacgatac gctgactcaa ttacatggtg cttcggttac gtatcgcatt
     1861 gccgtcggcc cccagcaagg gcgcaaagtc ttcaccctgc aaaccttgcc agggcgtgag
     1921 gataaagccg actcaagcag tcgagtagcc aaccatgctg gtttctcgct acacgccggt
     1981 gtgatggccg aagcgcatca gcgggataag cttgagcgct tgtgtcgcta cattagtcgg
     2041 ccagcggttt cagaaaaacg tctggcatta accgccaatg ggcaggtgcg ttacgagctc
     2101 aaaactccgt accgcaatgg caccacccat gtgatcttcg agccgctgga cttcatcgcc
     2161 aaactcgctg cgttggtacc taagccgcga gtcaacctca cacgcttcca cggcgtcttt
     2221 gcaccgaaca gcaaacaccg agttcaagta acacccgcca agcggggcaa gaagcccgac
     2281 aaatcggaag gtctcgatac taactggcgt gacaagagtc ctgcagagcg ccaccgcgcc
     2341 atgacctgga tgcaacgcct caagcgagtc ttcaatattg atattgaagt ctgcgaacac
     2401 tgcggcggtc acgtcaaagt gattgccagc atcgaagatc cgaaggtcat tgagcagatt
     2461 ctcaagcatc tgaaacagaa aacagccaag gcgaatgccg ccaagcagcg tgagctgcca
     2521 ccagaacgag cgccgccact gactcccagc ctgttcgatc catcacagag tcgtctcttt
     2581 gactgacgac cccaaatcca acactgctca acactgccaa cttttaaacg gggcggtggg
     2641 gcagtttgta tctctcgagc tatcaggcta gagattttac cgccaaatcg aaccttatta
     2701 gagcggttta ggctggaccg gcagttaaaa ttggggcttg agcggtaaac gagtgaggga
     2761 atttcaggta agatacttcg gatgaggagc aaaaaggtgg tttatacttc ctatacccca
     2821 taaaggaggc atccggttgc gttaagcgga attcaacggt gttgttgtcc agtttgcgca
     2881 cgctttggac gttatcggca aactgcaggc tgtcgaagta ggggaaactg ctgccgttca
     2941 cattgtgcca cggatggtgg cgatcaaaga tgcgctcgaa ggtaaacacc acatcgtctg
     3001 cattcagttt gcgggtgggg gtgaaccagg ccgtcttctg aaactgaacg tcacgacgca
     3061 gatggaagcg gtaggttgcg ccgttatcca gcacctccca gctttcagca agctcaggca
     3121 ccagccgata ggtgtaggga tctacatcaa gcagtcggtc atacaattgg gccgctaacg
     3181 tatcgacgat gagaccgctg ctcgtttttt gtgggttgaa cgtattgact tgcccgctga
     3241 cgcaatagac aaacccactg tcacggatat cagcgtgcgg agcttgctca ggcgcagcag
     3301 cagcctgacc actcagaaat ccagccatca cgatcagaga tgataaaacc aggcgcataa
     3361 ttttaatgga ttatataaag aggctatctt actaatactt aatgacattt gccattaccg
     3421 tttgtttttg ggagtaacag gctcgataag cgcgagttca acaccgcgac atggtcaaaa
     3481 ttcatacctg ctatccactt tgaatctact ctgttaacta tcttagcatt ttcatggccc
     3541 atctgacttg ctataaacgt gggggcgtac ctgtcgttgt ttactgattg atatcagtgt
     3601 gtgctcggaa gatggagtat ggcatcgata acgaagtgtg gagcgagcat ttagagtgtc
     3661 actatcaatg ctgaactata atcattcagg aagcagtaca cgttatgtga gttgtaatag
     3721 ctaaagtatc tataattatt tcaatatgtt aattccattt tttcttcatg gcatcttaat
     3781 cttctcaccc atttatggtg atgatttcca ttggttatta aatgcatttt ggctttgatc
     3841 ctggttatga acggttttct gttgccattt aacttctaat ggaatgaatt gtatgaataa
     3901 attactgagc cttgttgttt cacttgccct attgcctgga gccgtttttg cagcgtcgac
     3961 tccagactgt gtgaaggtga ataaagcgca aatcgaagcg ctatttgata agtggaacga
     4021 gtcattgaaa acaggtaacg cgcagacggt atctgaaaat tatcttagcg atgcggtatt
     4081 gttgcctact gtatccaata aagcgcgttt aacggacgct gaacgtgttg attatttcga
     4141 gcattttctt gcgaaaaagc cgaccgggaa aattgacatg cgtaccattc gcctggggtg
     4201 taataaggcg atagacaccg gtacctacac atttaccttc gcggacaaat caacggtttc
     4261 agcccgctac acattcactt atgcatggga cggtaaagag tggaaaattt ccacacacca
     4321 ctcttcagcg atgcctgaag ggtaaaaagc tgtgcagggg gcggaatatt caccgctccc
     4381 tgaagactag ccaataatcg cgatgccaag acgttccatg agcaacgatg cctggtagtt
     4441 gtccaactta acgccttgta aatcaacgcg ccgaatatct aagtcaccca actccgaatt
     4501 ggtcagatcg caatgtgtga agtttgctgc tcgccagtcg aaagtcgaaa actcgccgcc
     4561 ggagagatct gaaccactga acgtcgcgcc cagtacctgg gcccccatcc aacggttttc
     4621 ccacagctca cacttttcca acacgacttt cgaaaaattg gcgtagctta gatttgtgtt
     4681 agtgatatat gcactgcaaa accaggtgcg agtagtgatc atattcataa aacttgcgcc
     4741 gcgaaaatct gcgccttgcg cacgacagtg gcaaatttca atgccaagcg cactggcatt
     4801 gcgaaaatcc gccatggata aatcacagct tttaaaaatg gcatctttca gcatcgcacg
     4861 actaaaattg caccctttct ggctttcacg atcatagaac tgacagccga taaattcagt
     4921 gccgctcagg tcggcacctg aaaaatcaca gttaaaaaat gtactatttt caattttctc
     4981 accggtgaag cggtttctgt taattttttc gccaacgagt gccagagcca tattttgtgc
     5041 ctgttttttt atacagtaat ggcgtcatgg taaaccctga tgaggttatg cgtcaaatcc
     5101 gccaatataa catctgcaaa tgtgcgttaa atctggtgtt ttttcagcaa agcgcgaagc
     5161 tgatggtaag tcagacccag taattcagcg gcttttttct ggttaaattt tgcctgctgt
     5221 aagctggttt gtagaaagtc tttctcttgc tgctgctgga attcacgcag atccagcggt
     5281 aaccctacag acatcggttt agtttccggc gcctgcggct gcgtctggtt ctgaaatcca
     5341 tccctgtcgg tgttgcttat gcagtctggt cgggactcgg cgtcgtcata attacagcca
     5401 ttgcctggtt gcttcatggg caaaagcttg atgcgtgggg ctttgtaggt atggggctca
     5461 taattgctgc ctttttgctc gcccgatccc catcgtggaa gtcgctgcgg aggccgacgc
     5521 catggtgacg gtgttcggca ttctgaatct caccgaggac tccttcttcg atgagagccg
     5581 gcggctagac cccgccggcg ctgtcaccgc ggcgatcgaa atgctgcgag tcggatcaga
     5641 cgtcgtggat gtcggaccgg ccgccagcca tccggacgcg aggcctgtat cgccggccga
     5701 tgagatcaga cgtattgcgc cgctcttaga cgccctgtcc gatcagatgc accgtgtttc
     5761 aatcgacagc ttccaaccgg aaacccagcg ctatgcgctc aagcgcggcg tgggctacct
     5821 gaacgatatc caaggatttc ctgaccctgc gctctatccc gatattgctg aggcggactg
     5881 caggctggtg gttatgcact cagcgcagcg ggatggcatc gccacccgca ccggtcacct
     5941 tcgacccgaa gacgcgctcg acgagattgt gcggttcttc gaggcgcggg tttccgcctt
     6001 gcgacggagc ggggtcgctg ccgaccggct catcctcgat ccggggatgg gatttttctt
     6061 gagccccgca ccggaaacat cgctgcacgt gctgtcgaac cttcaaaagc tgaagtcggc
     6121 gttggggctt ccgctattgg tctcggtgtc gcggaaatcc ttcttgggcg ccaccgttgg
     6181 ccttcctgta aaggatctgg gtccagcgag ccttgcggcg gaacttcacg cgatcggcaa
     6241 tggcgctgac tacgtccgca cccacgcgcc tggagatctg cgaagcgcaa tcaccttctc
     6301 ggaaaccctc gcgaaatttc gcagtcgcga cgccagagac cgagggttag atcatgccta
     6361 gcattcacct tccggccgcc cgctagcgga ccctggtcag gttccgcgaa ggtgggcgca
     6421 gacatgctgg gctcgtcagg atcaaactgc actatgaggc ggcggttcat accgcgccag
     6481 gggagcgaat ggacagcgag gagcctccga acgttcgggt cgcctgctcg ggtgatatcg
     6541 acgaggttgt gcggctgatg cacgacgctg cggcgtggat gtccgccaag ggaacgcccg
     6601 cctgggacgt cgcgcggatc gaccggacat tcgcggagac cttcgtcctg agatccgagc
     6661 tcctagtcgc gagttgcagc gacggcatcg tcggctgttg caccttgtcg gccgaggatc
     6721 ccgagttctg gcccgacgcc ctcaaggggg aggccgcata tctgcacaag ctcgcggtgc
     6781 gacggacaca tgcgggccgg ggtgtcagct ccgcgctgat cgaggcttgc cgccatgccg
     6841 cgcgaacgca ggggtgcgcc aagctgcggc tcgactgcca cccgaacctg cgtggcctat
     6901 acgagcggct cggattcacc cacgtcgaca ctttcaatcc cggctgggat ccaaccttca
     6961 tcgcagaacg cctagaactc gaaatctaac gtccgttcgg gcatcgaggt ccatgtcggg
     7021 gtgggacggg cccgtggctt caagatcact tgcagtccga ccgcgatgtc ttggttgcgc
     7081 gagaggttgt cgatatcctc cacttccatc atcaaccctg gataatgccg ccgccgtcat
     7141 cgccgccgac gcccgtgccg ggcttttcgg gcctgtcagg cttgctcggc cttcagcctg
     7201 cctgggcgag atctccggcg gacggattaa cggcggagct tcgccgcctt tcgtgcgtgt
     7261 gaaggccgaa gatagttctc tcaaaaacat ccgtttatga gagataccaa atgtcatttt
     7321 cagaagacga ctgcaccagt tgattgggcg taatggctgt tgtgcagcca gctcctgaca
     7381 gttcaatatc agaagtgatc tgcaccaatc tcgactatgc tcaatactcg tgtgggctct
     7441 gttgcaaaaa tcgtgaagct tgagcatgct tggcggagat tggacggacg gaacgatgac
     7501 ggatttcaag tggcgccatt tccagggtga tgtgatcctg tgggcggtgc gctggtattg
     7561 tcgctatccg atcagctatc gcgaccttga ggaaatgctg gcggaacgcg gcatttcggt
     7621 cgaccatacg acgatctatc gctgggtcca gtgctacgcc ccggagatgg agaagcggct
     7681 gcgctggttc tggcggcgtg gctttgatcc gagctggcgc ctggatgaaa cctacgtcaa
     7741 ggtgcggggc aagtggacct acctgtaccg ggcagtcgac aagcggggcg acacgatcga
     7801 tttctacctg tcgccgaccc gcagcgccaa ggcagcgaag cggttcctgg gcaaggccct
     7861 gcgaggcctg aagcactggg aaaagcctgc cacgctcaat accgacaaag cgccgagcta
     7921 tggtgcagcg atcaccgaat tgaagcgcga aggaaagctg gaccgggaga cggcccaccg
     7981 gcaggtgaag tatctcaata acgtgatcga ggccgatcac ggaaagctca agatactgat
     8041 caagccggtg cgcggtttca aatcgatccc cacggcctat gccacgatca agggattcga
     8101 agtcatgcga gccctgcgca aaggacaggc tcgcccctgg tgcctgcagc ccggcatcag
     8161 gggcgaggtg cgccttgtgg agagagcttt tggcattggg ccctcggcgc tgacggaggc
     8221 catgggcatg ctcaaccacc atttcgcagc agccgcctga tcggcgcaga gcgacagcct
     8281 acctctgact gccgccaatc tttgcaacag agcccgccgt gctagtctgc tcggtgatgg
     8341 tggagtgaag ccaacccgca atcgggttat gaatctgcat cgcgattcgc aatcagctgt
     8401 ctcttgagca tgtcgaactc ctgcgatgtt atctcgccgt gctcgtgctg ctacaccaac
     8461 ttgtccaact catccgccac accgctcccc accacctgcg atggccaggt tgtttgctgg
     8521 gcgcattggc ggagtatcgt ctcgacccgg gacacccaca ccggcacaac cttacgggag
     8581 tgattcactg tcaaagaatc ggcccggtgc tctgacgcaa gtatcgggat ggtcaccatt
     8641 tgtaagccgt agacctgagt ggtgatcaag acttcgatac caccgaccgt accggtacta
     8701 atcgacgacg gtcgtgttcg tcgcctgccg cagggactct gcacacctcc gtttacgcat
     8761 gtgcctggag gagttggaaa tcgtcgtgtt cgggaaacat taaacacagg atggcagcga
     8821 tctgagccag cacatgatca gctagctcac catccggatc gacggcccac tgcatcgtcg
     8881 cgccagcgat gaccgagtgc aggagcaact cagctgccgc aggagcacct gggggcagtc
     8941 gcttgcggat cccctccacc accgcgcggt tccgctggat cgcaagcgtg cgtagctccg
     9001 gcacctggag ctcgtaccag gagatgagat agttcaccga gaagtcgttg cgagtgttca
     9061 tgctccgaac gagcacctgc aaaaattccc agagcccttg cggccctgcg cctatcggta
     9121 tcgcattcag gtaatgccgc acctgctcga cgccgcgctc catcatcctc accagcagcg
     9181 tatcgcggtt ggtgaagcgc tggattaacg ctgcgcggga gagccccacc tcctttgcta
     9241 ctccgctgag cgtgaactct atgggaccgc aacgcttcag cactacggtg gcggcctcga
     9301 gtacctcgtc atcggacttg agcttggggc ggggcatcag tgttcacctt ctgtatgggt
     9361 tggggcggag gctgtggctg ccgccgccat tgtagcaaat tgaagacgga gcgagagtag
     9421 agccacgagc cccgcaaaca cggccgatac aacgaggcca gggagcggac cagcaaggtc
     9481 gacaaacgcg ccggccgcaa gcataaccat gggcgaggct gacagcatca ccgccgagac
     9541 cgtgccgagt acccggccga gaagttctgg cggcgtgcgg ttgtagatgg cagcgttgag
     9601 aatgggagag actgagccgg tcagcagtcc cacgagcgcg cccaacaaca tcagcaccgg
     9661 cacgcctggc aactgtgaaa gcagaagcga gcccaccgca gagccacaaa atgccaccgc
     9721 cagccagttc tgcgctgata tccgggcgcc gaccgacgca tgaatggcaa tgccaaggag
     9781 accaccagcc cccatcattg aggagaacag cccgagctct gctacttggc gtcctgcatc
     9841 tacaaacagc gcaggcatga tgacgctgcc gttggcgcca acgatgccca cgaagatcat
     9901 cactatacca aagagagggc gcagcagggg ttcgctccag agaaaagcga cgccggcgcg
     9961 catggagaga gtcgccgtcg tggtcatcgt ccgagcggca cgcgcgggaa gcacccacgc
    10021 gccgagcaga cctgcaagga cggagcagaa cgccgtcagc ccgagcgttg gcgcagcgcc
    10081 aagcaggccg attgcggccc ccccaagggc cgggccacct agaatcgcga cgttcccgat
    10141 caccgctttc agtgacgaga cgcgctcaac ggagagcccg gcgacgtggc cgagtttggg
    10201 cagctcactg tcctgcgcgg ccataccggg tgcgtcgaac gcggcaccga gcaccacgca
    10261 agcgatcagc ccagtgttcg agagggcgcc aacggcatcg agcagtggga tgctcgccat
    10321 ggccacgccg cccaccacac ccgagatcaa tgcgacgggc gcgcgcccga accgatcgac
    10381 gaggccacca ccaacccacg cgccgatgat ggtcgcgatg acgctgctag cggccgtggc
    10441 gcccgcccag gccgcgctct ttgtatgaga caggacgaac catggaagcg cgagggccgc
    10501 caccgcgttg ccgatccgga agagaaaggt cgccgcgaac agcgtcgcga gcgggctata
    10561 tcgacgttcg ctcattccgc tgcggcgagc tgcgccttcg ccgcagcgag gtactcttcg
    10621 ttacccgagt cgagggcgaa gagtgcgtag gtgaccgccc cgaacgcaag gcgctccgcg
    10681 atgtggtggg cgagccgcgg ccacacccgg ccaccggccg cttcatacgt gaggaggagc
    10741 ttcgcgagcc cctcttcacc aaagaccata aggtgcgcgg ccatgtcgat ggcagggtca
    10801 tcaacgcggg cctcgctcca gtcgatcatc ccgctgacgc gctccgtgtt gtcgatgagc
    10861 acatggccca cgtagagatc gccatgcacc accacggaga aatctggcca cgacgaatcg
    10921 tcgtcgagcc agcgctgcca ccggtggagg cgcttgtcgt tcaccacgaa ctcgcgtcgg
    10981 acgcggtcaa cgtcgtcggc caccttctga cgggcctgcg tcggtgtacg gatgagcatc
    11041 cccgcatcca cggcggcgga aatggggacg gcatgcaggg cggcgagcgc ggtcgcgaag
    11101 ctctccgcga agacctccga gtcctgcggc acgacccagt cgggcgtgga cgaaccaggc
    11161 tggatgacca tcgcagtcga gtcttcgagc atgggatagg caacgagctc ggcgttggcc
    11221 acgcgccagt ccggcaccgc gaacggcagg cgattcttga gcattgccag cacccgcgcc
    11281 tctggttcga ccttcgcgct tacctcggct cggcgcggga tgcgcagcac ccaccgacgt
    11341 ccatcgtcga cggtggcgat cacgatccta tagtcgagcc caagctcatt gacagtcagc
    11401 gggccatgga gcttgagccc atgtcgggct gcaagtgcgt acagttggga ggtatcggcg
    11461 gtcgtgacta cggtcatgat tcactcctga gggcttgacg ggtttagcca cctaaatgta
    11521 acagtcacgt cggttatatt caatccggca ctgttgcaaa gttagcgatg aggcagcctt
    11581 ttgtcttatt caaaggcctt acatttcaaa aactctgctt accaggcgca tttcgcccag
    11641 gggatcacca taataaaatg ctgaggcctg gcctttgcgt agtgcacgca tcacctcaat
    11701 acctttgatg gtggcgtaag ccgtcttcat ggatttaaat cccagcgtgg cgccgattat
    11761 ccgtttcagt ttgccatgat cgcattcaat cacgttgttc cggtacttaa tctgtcggtg
    11821 ttcaacgtca gacgggcacc ggccttcgcg tttgagcaga gcaagcgcgc gaccataggc
    11881 gggcgcttta tccgtgttga tgaatcgcgg gatctgccac ttcttcacgt tgttgaggat
    11941 tttacccaga aaccggtatg cagctttgct gttacgacgg gaggagagat aaaaatcgac
    12001 agtgcggccc cggctgtcga cggcccggta cagatacgcc cagcggccat tgaccttcac
    12061 gtaggtttca tccatgtgcc acgggcaaag atcggaaggg ttacgccagt accagcgcag
    12121 ccgtttttcc atttcaggcg cataacgctg aacccagcgg taaatcgtgg agtgatcgac
    12181 attcactccg cgttcagcca gcatctcctg cagctcacgg taactgatgc cgtatttgca
    12241 gtaccagcgt acggcccaca gaatgatgtc acgctgaaaa tgccggcctt tgaatgggtt
    12301 catgtgcagc tccatcagca aaaggggatg ataagtttat caccaccgac tatttgcaac
    12361 agtgcccttc gagcagcagc gctaccgggc cagcggcctc aacctggtga cggcggctat
    12421 cgtgctgtgg aacacggtgt acctggaacg cgccacccag gggttggtcg aggccggcaa
    12481 gccggtggac ggcgagctgc tgcaattcct gtcgccgctg ggctgggagc acatcaacct
    12541 aaccggcgat tacgtctggc ggcagagccg cagactggaa gacgggaagt ttcggccctt
    12601 acggatgccc ggaaaacctt agcgtacgat tttttccgaa ttctgcgggc tcccctatct
    12661 catctgcgca aggcagaacg tgaagacggc cgccctggac ctcgcccgcg agcgccaggc
    12721 gcacgaggcc ggcgcgcgga cccgcgccac ggcccacgag cggacgccgc agcaggagcg
    12781 ccagaaggcc gccagagagg ccgagcgcgg ccgtgaggct tggacgctag ggcagggcat
    12841 gaaaaagccc gtagcgggct gctacgggcg tctgacgcgg tggaaagggg gaggggatgt
    12901 tgtctacatg gctctgctgt agtgagtggg ttgcgctccg gcagcggtcc tgatcaatcg
    12961 tcaccctttc tcggtccttc aacgttcctg acaacgagcc tccttttcgc caatccatcg
    13021 acaatcaccg cgagtccctg ctcgaacgct gcgtccggac cggcttcgtc gaaggcgtct
    13081 atcgcggccc gcaacagcgg cgagagcgga gcctgttcaa cggtgccgcc gcgctcgccg
    13141 gcatcgctgt cgccggcctg ctcctcaagc acggccccaa cagtgaagta gctgattgtc
    13201 atcagcgcat tgacggcgtc cccggccgaa aaacccgcct cgcagaggaa gcgaagctgc
    13261 gcgtcggccg tttccatctg cggtgcgccc ggtcgcgtgc cggcatggat gcgcgcgcca
    13321 tcgcggtagg cgagcagcgc ctgcctgaag ctgcgggcat tcccgatcag aaatgagcgc
    13381 cagtcgtcgt cggctctcgg caccgaatgc gtatgattct ccgccagcat ggcttcggcc
    13441 agtgcgtcga gcagcgcccg cttgttcctg aagtgccagt aaagcgccgg ctgctgaacc
    13501 cccaaccgtt ccgccagttt gcgtgtcgtc agaccgtcta cgccgacctc gttcaacagg
    13561 tccagggcgg cacggatcac tgtattcggc tgcaactttg tcatgcttga cactttatca
    13621 ctgataaaca taatatgtcc accaacttat cagtgataaa gaatccgcgc gttcaatcgg
    13681 accagcggag gctggtccgg aggccagacg tgaaacccaa cagacccctg atcgtaattc
    13741 tgagcactgt cgcgctcgac gctgtcggca tcggcctgat tatgccggtg ctgccgggcc
    13801 tcctgcgcga tctggttcac tcgaacgacg tcaccgccca ctatggcatt ctgctggcgc
    13861 tgtatgcgtt gatgcaattt gcctgcgcac ctgtgctggg cgcgctgtcg gatcgtttcg
    13921 ggcggcggcc ggtcttgctc gtctcgctgg ccggcgctgc tgtcgactac gccatcatgg
    13981 cgacggcgcc tttcctttgg gttctctata tcgggcggat cgtggccggc atcaccgggg
    14041 cgactggggc ggtagccggc gcttatattg ccgatatcac tgatggcgat gagcgcgcgc
    14101 ggcacttcgg cttcatgagc gcctgtttcg ggttcgggat ggtcgcggga cctgtgctcg
    14161 gtgggctgat gggcggtttc tccccccacg ctccgttctt cgccgcggca gccttgaacg
    14221 gcctcaattt cctgacgggc tgtttccttt tgccggagtc gcacaaaggc gaacgccggc
    14281 cgttacgccg ggaggctctc aacccgctcg cttcgttccg gtgggcccgg ggcatgaccg
    14341 tcgtcgccgc cctgatggcg gtcttcttca tcatgcaact tgtcggacag gtgccggccg
    14401 cgctttgggt cattttcggc gaggatcgct ttcactggga cgcgaccacg atcggcattt
    14461 cgcttgccgc atttggcatt ctgcattcac tcgcccaggc aatgatcacc ggccctgtag
    14521 ccgcccggct cggcgaaagg cgggcactca tgctcggaat gattgccgac ggcacaggct
    14581 acatcctgct tgccttcgcg acacggggat ggatggcgtt cccgatcatg gtcctgcttg
    14641 cttcgggtgg catcggaatg ccggcgctgc aagcaatgtt gtccaggcag gtggatgagg
    14701 aacgtcaggg gcagctgcaa ggctcactgg cggcgctcac cagcctgacc tcgatcgtcg
    14761 gacccctcct cttcacggcg atctatgcgg cttctataac aacgtggaac gggtgggcat
    14821 ggattgcagg cgctgccctc tacttgctct gcctgccggc gctgcgtcgc gggctttgga
    14881 gaaattcttc aaattcccgt tgcacatagc ccggcaattc ctttccctgc tctgccataa
    14941 gcgcagcgaa tgccgggtaa tactcgtcaa cgatctgata gagaagggtt tgctcgggtc
    15001 ggtggctctg gtaacgacca gtatcccgat cccggctggc cgtcctggcc gccacatgag
    15061 gcatgttccg cgtccttgca atactgtgtt tacatacagt ctatcgctta gcggaaagtt
    15121 cttttaccct cagccgaaat gcctgccgtt gctagacatt gccagccagt gcccgtcact
    15181 ccgcggtctt cactgcgtga tcgagttgat cgacacccgc cgtgacacgc tccatgaagt
    15241 gcctgcctgc gtctgttagc cgaacgcccc gcgcatggcg ctcaaatagc aggacaccaa
    15301 ggttatcctc cagcgctttc acacgcgcgc tgacgctcga ctggctgata ccaagtgcct
    15361 tggccgcatg ccgaaaattc agatgctcgg cgacggcgat gaactgaaca agggaaatga
    15421 gcggtatcct gccagacagg ataccgacat tcacgaggtt tcgatggtta gtgcgccgca
    15481 tcggagcggg cctgctacca gtcgtcggtt agacgactgg cgacttctcg gtggcagccc
    15541 cacggagccg aaggagcacc agccccaacg aaaccagtac cgccatcgcc gtggcgtaac
    15601 agatcacggg ccacgctgtg tcaccgttta aaagtgccac cgccaatgtc ccgacaatgc
    15661 tgactatcag gctttgaacg cagaagtaga acgcgaccgc tgatcccgcg atgtcgtcga
    15721 actctgccaa agcgccgttc gcggtaacgg acaccgtgaa gacaataccg accgcgacaa
    15781 cccacatcgg taggatgaag gtgaggaatg acggcgagcc gtaaagttcg ccgatcccca
    15841 acaggaccgc tccgcaaaca agcaacgcca tcccacgcgc cacgcatcct gcgatgcccc
    15901 atctggcgac aaaggacttc gcgaaacggg ttgtcacgat cattacaagc gcgacagtgg
    15961 cgaaggcaaa gctgaatccg atctcggaat attccgcttg gcctatgagc acacgggtag
    16021 ccgtcgagaa gaagacgaag taggtgccca taccggcgct aaagccgaca gtgtaaaccc
    16081 aaaaagccgg actcgcgaag atcggcaaga cagatcggcg cgtcttgact tgatccagag
    16141 ggcgggtttc gtgccacctg aaacccgcat ttaggagtgc gagcatcgcc agtatagcca
    16201 aagtaatgaa tatcgcctgc catcccaaga actcgccgat caatgctccg gcgatagggc
    16261 cgagcgcagg cacgaacgcc agcatcgaac tgaaaaggcc gtagatgacg acaccctcag
    16321 gacggttggc ataaacgtcg cgaaccgtcg cgaacgtcgc caccagcatg gccgacgcgc
    16381 ccactgcttg aagtagacgg aaagcgacaa aggccggtgc agttgaagac caagctgctc
    16441 ccagagacgc aatgacgaaa gccgttgcgc ccgcaagtag aattggccgt cgcccgattc
    16501 tgtctgagag cggaccaaaa atcacctggc ccacgccgag catcaccata tagaggctca
    16561 acgtgagttg gatcatagcg ggcgtcgtgt tcaggatgcc gggcatcgct ggaacgacag
    16621 ggagataaat atccatcgcc agtgaagcga ggatgtcgaa aggagccatc agcagcagtg
    16681 ctgccggcag cgtataggcc cacgcggggc gtgtggtggt catgacgaat caaccctcga
    16741 ttaaggaata ccgggcgacg tctgctcgtc agcaatcaga tgagactagc cttacagagc
    16801 gccgcaacaa caatactggt tgttgcggct tacttgtctg ctgacttgga atttcccatc
    16861 tgattactcc acgcttacga atatgaattg ctacatttta tccgattatc ttttgcttcg
    16921 caatgcggca tgggcgcact cagcgttcca gccccctctg ccgccctaac tgccacgaca
    16981 ccgacccgcc ctgcacgatg cccataacct cgcggccgag ttggcggtcg atgatcggcc
    17041 gccacgggac aagggtgaac tcatgggatt tctcgaccac ggcgaacttg ccgctcgata
    17101 gatgcacggt tccggtaaac ttgccgctga cgctctcgcc gtccgtggcg gcgcggaacg
    17161 gcaggccctt actcaaagcc atatccgatc cgacgccggc tacctcgcgc tcccgcagga
    17221 tggcgagaag gttgcgccgg tagaagacgc ggctgtcccg gctgcgggtg gcgtcgccct
    17281 gttcgatatg gtgctcgcgg cgctggtcca tggcttcgcg gacttgttgc ccgaagccgg
    17341 ttggcgcaag gtcggccgtc tcgccgtgga tcagccgccg gtccagccag gtcgcgccgt
    17401 ccgatccgat ctgtttgttc agatcgaccg gggaaaggac gcgaacgctg gcctgactgt
    17461 ctcggccggc gtcatgggcg gcggcacggc tgaccagatc atcggggatg cgccattggt
    17521 cggcgtcgat ccgctcgacg ataccggccc ggcgtagcgc ctccagccgg cgcacatggg
    17581 catcgacata gccctcatag tcgccgcctg gaacgcggca cgtataggaa gaataagggg
    17641 tctgacgctc agtggaacga aaactcacgt taagcaacgt tttctgcctc tgacgcctct
    17701 tttaatggtc tcagatgtcc tttggtcacc agttctgcca gcgtgaagga ataatggccg
    17761 agcatattga tatgtccgtg gcaaagcggg gagaggcgtg cgatatcttc atcattcagt
    17821 gtttcaccct gcgcccggag atgatccagg gctgcctgca tataaatagt gttccataac
    17881 acgacggcgt tagtgaccag ccccagtgcg cccagttgat cttcctgacc gtcggtatat
    17941 cgttttctta tctcaccttt ttgaccgtga cagatggctc tggcaacggc atggcgactt
    18001 tctccccgat taagctgggt cagaatgcgc cggcggtaat cttcatcatc aatataatta
    18061 agcagataca gcgttttgtt gatgcgcccc acttcaatga ttgcctgagt cagtccggaa
    18121 ggacgttcac ttttcagcaa tgaacggacc agcactgaag cctgtacttt gcccagcttc
    18181 agggagccag cggtccggat catttcgtcc cactgaagga ctatttttcg gggatctgat
    18241 tgccctctgg caatatcatt cagcacgcca tagtcggcat catggtccat tcgccagaaa
    18301 accgaagcac cggcatcagc caggcgtgga gaaaactggt atcccagcag ccagaaaagg
    18361 ccaaagacaa gttcgctggc acctgctgta tcggtcataa tttcggttgg attcagcccg
    18421 gtctcctgtt ccagaagacc ttccagcaca aagatagagt ccctcagcgt ccccggtata
    18481 acgatgccat gaaagccgga atactgatcg gacacaaagt tgtaccaggt gatccctctg
    18541 ttattaccaa agtatttgcg gttcggtccg gcattgattg ttctgactgg cgtaacaaag
    18601 cgcattccat ctgcagatgc cacttctcct ccaccccata tctgtgccag tggcagcgtt
    18661 gcctgaaaat caaccagtct ggcattagcg ctggtgatag tttcagcccg cagatagttc
    18721 gcttttgtcc agttcagccg gtgtcgggtc agtgcaggaa catttgatct gatcagtggt
    18781 tccagaccga tattgcaggc ttcagccatc agcacggcgc tgatgctgac gggcagatca
    18841 tcaactctgg cactggcttc actagcatgg aaaaactcat cagcaaatcc ggtatgggcg
    18901 ttaatttcga gcagcaactc cgttaaatcc accggaggga gtagatcact gatcattttg
    18961 ctcagtcgtt tcagactgtc cggctcatca agactggcga ggggagaaat tgtcaaccgg
    19021 ggcttcgggc cagaaacatc gagttcgaca gcctcatttt cgcaaagacg tgcagcaacc
    19081 tgtctgtaac gactatcaag ctgatgaccc agagatttta ttgcttcctg cgggtctgtc
    19141 gggtgcccca aagaacgata aaccttaatc cggtttgcct gccagtcagc accctgtagt
    19201 aatcttgcac gaggatctcc ccaccggtta ctgccggtaa cgtagacatc cctccgcctc
    19261 agactatcct gcagtttact gagaaagcag agcgtgtatc ccctgcgggt gatatgtttt
    19321 tccttgttaa tcaccagccg tttccatgac cgactgataa tttccgttgg tgcgtcgtca
    19381 aaaaactgcc gccgtgagct gaactcccgg ctgaggtagt cacaggcatt cagagtggta
    19441 accccggcag gtgcggatga aaatttaacg gtattcagca gatggggcag gaaacgacga
    19501 acgcgcccgt actgctccac catttcttca tgaaaattat cgtctgaggg ccgggcaatt
    19561 tcacggacaa gcgtgatgat ttcagccagc ttttgccttg ggatgtagct gaacacctca
    19621 gcacgaatcg attcgtccgg tgtttcttct ttcagcaggt acgaacatgc gctggcgagc
    19681 gccaatgcag atttatccag atccttcagc gagcggagcc gttttttctg cccaatcttt
    19741 ctggcgtcac ggatgataac ggccagcatg gcgtccagaa cgtccaatgc atcatccagc
    19801 gccagcgttt cccatgcaag gacaaaggca accagaaccg ccatcctttt ctgcggtgac
    19861 atcctggcaa tattgaacac cgaagtcata ccagcataac gtgcgagatt tttcaggcgc
    19921 acagccggga gtgtactcag gttttcagca tgcaggccaa aatcgttcag agttttccag
    19981 cgttcaattg cttcattaaa cgccggacca ctgatggtca cagggccctt tttcagtgat
    20041 tccagtaaag acaggcggct gcaatcagtt ggccccagca gcatctccag ctgtgaacgc
    20101 tgttcggctg acggtatcag tgccagtttg ttccacaggc gcaacgtcgc cttttccctt
    20161 acctctgaaa tcaaccgggt cagcgtagtg gctccgggga gaataatacg atgttgcata
    20221 agccaccctg tcgccagatc gaaaagcagg ccaggacgtt cgttgcttat ccagctccgg
    20281 gtatataaaa gacgggtaag gcgaaatgtc cagggccagg caaattcacg atactgatag
    20341 tgctgacgta tcagcgctgc atgctcacgg cgggtatttt ccctctgacc gtattctgca
    20401 agaacggtga tatcacgaat cccgagctgt ctggcggtaa aatgccggac gccggaagga
    20461 atatgattca tatcggtgag gaaggtgccc agaaaacgga cacatccaat ttgcagggca
    20521 atgcccagac ggttgtgatc acctctgctt tttccgataa attccttgtc tgcttcatca
    20581 aggtgaaaat atcgtgccag ctgaagctca tccggttcac cggtgaatct gccatagctt
    20641 tcagtctgct cagtggtcag aaagtcaacg ggcatatcgg cctccctgcc tgacgggcat
    20701 ttagtaacat ttttccaacc gtacgaaatg ttataaatta tcggacatcg taaaactgtt
    20761 acattaatat gtctattaaa tcgtaaattt gtaataatag acatgagttg tccgatattc
    20821 gatttaaggt acatttttat gcgacttttt ggttacgctc gggtctcaac cagtcagcag
    20881 tctcttgatc ttcaggtcag agcactcaaa gacgcaggtg tgaaagcaaa ccgtatattt
    20941 accgataagg catccggcag ttcaacagac cgggaagggc tggatttgct gaggatgaag
    21001 gtggaggaag gtgatgtcat tctggttaag aagctcgacc gtcttggccg cgacactgcc
    21061 gatatgatcc aactgataaa ggaatttgac gctcagggcg tggcagtccg gttcattgat
    21121 gacgggatca gtaccgacgg tgatatgggg caaatggtgg tcaccatcct gtcggctgtg
    21181 gcacaggctg aacgccggag gatcctagaa cgcacgaatg agggccgaca ggaagcaaag
    21241 ctgaaaggaa tcaaatttgg ccgcaggcgt accgtggaca ggaacgtcgt gctgacgctt
    21301 catcagaagg gcactggtgc aacggaaatt gctcatcagc tcagtattgc ccgctccacg
    21361 gtttataaaa ttcttgaaga cgaaagggcc tcgtgatacg cctattttta taggttaatg
    21421 tcatgataat aatggtttct tagacgtcag gtggcacttt tcggggaaat gtgcgcggaa
    21481 cccctatttg tttatttttc taaatacatt caaatatgta tccgctcatg agacaataac
    21541 cctggtaaat gcttcaataa tattgaaaaa ggaagagtat gagtattcaa cattttcgtg
    21601 tcgcccttat tccctttttt gcggcatttt gccttcctgt ttttgctcac ccagaaacgc
    21661 tggtgaaagt aaaagatgct gaagatcagt tgggtgcacg agtgggttac atcgaactgg
    21721 atctcaacag cggtaagatc cttgagagtt ttcgccccga agaacgtttt ccaatgatga
    21781 gcacttttaa agttctgcta tgtggtgcgg tattatcccg tgttgacgcc gggcaagagc
    21841 aactcggtcg ccgcatacac tattctcaga atgacttggt tgagtactca ccagtcacag
    21901 aaaagcatct tacggatggc atgacagtaa gagaattatg cagtgctgcc ataaccatga
    21961 gtgataacac tgctgccaac ttacttctga caacgatcgg aggaccgaag gagctaaccg
    22021 cttttttgca caacatgggg gatcatgtaa ctcgccttga tcgttgggaa ccggagctga
    22081 atgaagccat accaaacgac gagcgtgaca ccacgatgcc tgcagcaatg gcaacaacgt
    22141 tgcgcaaact attaactggc gaactactta ctctagcttc ccggcaacaa ttaatagact
    22201 ggatggaggc ggataaagtt gcaggaccac ttctgcgctc ggcccttccg gctggctggt
    22261 ttattgctga taaatctgga gccggtgagc gtgggtctcg cggtatcatt gcagcactgg
    22321 ggccagatgg taagccctcc cgtatcgtag ttatctacac gacggggagt caggcaacta
    22381 tggatgaacg aaatagacag atcgctgaga taggtgcctc actgattaag cattggtaac
    22441 tgtcagacca agtttactca tactgaaata attggggggt gattaccacc gtaaattttt
    22501 cccagacggt aaaaagaatt acagactttt atcaactaaa aaagtggcct gaatatcagc
    22561 actaccgtca ataccatttc agtaaatcag gatagggaaa aattggcaaa cccagttctt
    22621 cacttgctct gcgggttctg tcaccctgac gtcatacggt aatccccccc aattcattaa
    22681 tcgacaaggt catcctgatg aaacaaatta ccatgagcga tatgcagcaa cagagcgcag
    22741 cggctgtgca atcgcctcgg ctccgcgcgc accgtaattt ccatccagaa ttaagcgatt
    22801 cggtccaacg tctggctatt gccatggaac ctgggaccta cgtgcgcccg caccgacacc
    22861 ctcacacctt cgagctactg ttgccattaa ggggtcgttt cgtggtgctg aattttgacg
    22921 atcggggtac cgtcacccat cgggcgatat tgggggaaac ctgtacggtg ctggagatgg
    22981 ccgcaggaac ctggcatgcc gtgctgtcgc tggataccgg tggcataatt tttgaagtaa
    23041 aacacggtgg ctatcaaccc gtggctgccg atgactatgc gcactgggct ccagcggaag
    23101 gagaaccagg aaccacggag cttatggcct ggtatgcgca agcgcaggtg ggcgacagca
    23161 cttttgccgt ctaaggcgat aaacaaaaac ggaatgagtt tccccattcc gtttccgcta
    23221 ttacaaaccg tcggtgacga ttttagccgc cgacgctaat acatcgcgac ggctttctgc
    23281 cttaggttga ggctgggtga agtaagtgac cagaatcagc ggcgcacgat cttttggcca
    23341 gatcaccgcg atatcgttgg tggtgccata gtcaccgctg ccggttttat cccccacaac
    23401 ccaggaagca ggcagtccag cctgaatgct cgctgcaccg gtggtattgc ctttcatcca
    23461 tgtcaccagc tgcgcccgtt ggctgtcgcc caatgcttta cccagcgtca gattccgcag
    23521 agtttgcgcc attgcccgag gtgaagtggt atcacgcgga tcgcccggaa tggcggtgtt
    23581 taacgtcggc tcggtacggt cgagacggaa cgtttcgtct cccagctgtc gggcgaacgc
    23641 ggtgacgcta gccgggccgc caacgtgagc aatcagctta ttcatcgcca cgttatcgct
    23701 gtactgtagc gcggccgcgc taagctcagc cagtgacatc gtcccattga cgtgcttttc
    23761 cgcaatcgga ttatagttaa caaggtcaga ttttttgatc tcaactcgct gatttaacag
    23821 attcggttcg ctttcacttt tcttcagcac cgcggccgcg gccatcactt tactggtgct
    23881 gcacatcgca aagcgctcat cagcacgata aagtatttgc gaattatctg ctgtgttaat
    23941 caatgccaca cccagtctgc ctcccgactg ccgctctaat tcggcaagtt tttgctgtac
    24001 gtccgccgtt tgcgcataca gcggcacact tcctaacaac agcgtgacgg ttgccgtcgc
    24061 catcagcgtg aactggcgca gtgatttttt aaccatggga ttccttattc tgaaagagac
    24121 gaaataacaa caacatgaat agtcaatatt ttacctgaag cgagccacaa cgcgtccgat
    24181 tttatgcttc cgaaaggcaa atacggacgt cgccagaatg aaacctaaat tccacgtgtg
    24241 ttttttatta gcttcaaaaa tcactatttc acgaagaatt tagactgctt ctcacacatt
    24301 gtaacattat ttacaaccac ctttcaatca tttttgataa atcattgatt tcatctttgc
    24361 tgcaatgata cttaataaac tctgcaagtt atccacagag caacactcaa ttttattgat
    24421 gatattctta ttataccaga catttttcat acactccctt gtacggatag ttttccgaca
    24481 acttcatgat tacatatctt gcggttttga ttatttttgc tgcaagaaat acatacttca
    24541 aacgaaaggt ctttatttgc tgtctgtatt ctgaagagtc caaggaatca aacttgaaca
    24601 acaaaaatag gttatatgaa agcatcggta atggtgccaa cttactgatt tagtgtatga
    24661 tggtgttttt gaggtgctcc cgtggcttcc atctccatca gttgtccctc ctgctcagct
    24721 actgaaggcg tggtgcgtaa cggtaaaagt actgccggac atcagcgcta tctctgctct
    24781 cactgccgta aaacatggca actgcagttc acttacaccg cttctcaacc cggtacacac
    24841 cagaaaatca ttgatatggc catgaatggt gttggatgcc gggcaaccgc ccgcattatg
    24901 ggcgttggcc tcaacacgat tttacgtcac ttaaaaaact caggccgcag tcggtaacct
    24961 cgcgcataca gccgggcagt gatgtgattg tctgcgctga aatggacgaa cagtggggct
    25021 acgtcggtgc taaatcacgt cagcgctggc tgttttacgc gtatgacagg atacggagga
    25081 cggttgtggc gcacgtcttc ggtgaacgca ctctggccac actggagcgt cttctgagcc
    25141 tgctgtcggc ctttgaggtc gtggtatgga tgacggatgg ctggccgctg tatgaatccc
    25201 gcctgaaggg aaagctgcac gtaatcagca agcgttacac tcagcgcatt gagcgacata
    25261 acctgaatct gagacaacat ctggcaaggc tgggacggaa gtcactgtcg ttctcaaaat
    25321 cggtggagct gcatgacaaa gtcatcgggc attatctgaa cataaaacac tatcagtaag
    25381 ttggagtcat taccaaagta gtcgtattcg gaaccttcta aaagtgataa ttgtgctctt
    25441 tctttttctg gtttcagtac gcgagatacg acaaatcttc tgtctttttc ccatttaact
    25501 aattttgtat acagttctgt agtttctcta ccttcttctc ctttaacgaa tacaattgat
    25561 gaattcgttg cttgtgaggt gagtgtagaa taacttttgg ctttaattaa atatttgcat
    25621 ccaagagatt ctatcgtttc gataattttt tcatcaaagt agccactatc cattcgaaat
    25681 aaaatttcta aatcgtctga tttgatgtta gcaacaattt ctttgatcat ttccgcagca
    25741 ccgtttgcag tgtaagtatt gccacttctt acaaatccgg taacatatgc ttttaattcg
    25801 tcgcaaaatg caaattggat attgtagcat cggtttccca gtttcttagg attatatcct
    25861 tttgacgcac cttcttgatg accttctacg ttaattacac tactatcaat atcaatcgta
    25921 atggatgtca atttactttt agtgagcagt tttttaaaga ctttaaaatt aatgtctcta
    25981 aacatttggg ttgtcttgaa gttgaagttt cctagaaacc gtgacactgt ttcaggttct
    26041 tttacggaaa tatcaaactc gttgacgagg ggatcatttt gaagtagctt tagacgttct
    26101 aacttatcaa tgccaatgaa gtgaccgcag agcatggtct ttatatgatt catcttgatt
    26161 ttatttgttg agtcattatc aaatacgagg tcattttcaa taaaatcaaa aatcccattg
    26221 ctttttgcat tctcaaggag cagaaaaaga cctgcatttg atgttagatt cttagctttg
    26281 aaatcaattt tattaatcat aattagaacc cctttttact acttttctta ctattatttt
    26341 accatatatc gagtcataaa agctgataat ttaacatatt tttgagcact tttctttcac
    26401 ccaatgggtg aaagctgaat ttcgaaggaa tgcatattta tcaaggcttt gattatgctt
    26461 tttgaagtac tgacgtagaa tctaggtcat atatacttta gattgattta aaacttcatt
    26521 tttaatttaa aaggatctag gtgaagatcc tttttgataa tctcatgacc aaaatccctt
    26581 aacgtgagtt ttcgttccac tgagcgtcag accccgtata gtgttttgca gtttagagga
    26641 gatatcgcga tgcatacgcg gaaggcaata acggaggcgc ttcaaaaact cggagtccaa
    26701 accggtgacc tcttgatggt gcatgcctca cttaaagcga ttggtccggt cgaaggagga
    26761 gcggagacgg tcgttgccgc gttacgctcc gcggttgggc cgactggcac tgtgatggga
    26821 tacgcgtcgt gggaccgatc accctacgag gagactctga atggcgctcg gctggatgac
    26881 gaagcccgcc gtacctggct gccgttcgat cccgcaacag ccgggactta ccgtgggttc
    26941 ggcctgctga atcaatttct ggttcaagcc cccggcgcgc ggcgcagcgc gcaccccgat
    27001 gcatcgatgg tcgcggttgg tccgctggct gaaacgctga cggagcctca cgaactcggt
    27061 cacgccttgg gggaaggatc gcccgtcgag cggttcgttc gccttggcgg gaaggccctg
    27121 ctgttgggtg cgccgctaaa ctccgttacc gcattgcact acgccgaggc ggttgccgat
    27181 atccccaaca aacggtgggt gacgtatgag atgccgatgc ttggaagaga cggtgaagtc
    27241 gcctggaaaa cggcatcgga ttacgattca aacggcattc tcgattgctt tgctatcgaa
    27301 ggaaagccgg atgcggttga aactatagca aatgcttacg tgaagctcgg tcgccatcga
    27361 gaaggtgtcg tgggctttgc tcagtgctac ctgttcgacg cgcaggacat cgtgacgttc
    27421 ggcgtcacct atcttgagaa gcatttcgga accactccga tcgtgcctcc gcacgaggcc
    27481 gtcgagcgct cttgcgagcc ttcaggttag aggccgtcga caatgataat ctggatcaac
    27541 ggacctttcg gcgccggaaa gacgacgctc gctaagcggc tgcgcgatcg gcgttccaaa
    27601 tcgctgatct ttgaccccga ggaaatcggg ttcgtggtga aagaaacggt ccccatgcca
    27661 gcgagcggag actatcagga tctccccttg tggaggggac ttacgatcgc ggcggtcagg
    27721 gagattcgaa ggaattactc gcaggacatc atcatcccaa tgacgctcgt gcacccggac
    27781 tatctgactg agatactcga cggggtaagg cggatggcac tgttgcaaat agtcggtggt
    27841 gataaactta tcatcccctt ttgctgatgg agctgcacat gaacccattc aaaggccggc
    27901 attttcagcg tgacatcatt ctgtgggccg tacgctggta ctgcaaatac ggcatcagtt
    27961 accgtgagct gcaggagatg ctggctgaac gcggagtgaa tgtcgatcac tccacgattt
    28021 accgctgggt tcagcgttat gcgcctgaaa tggaaaaacg gctgcgctgg tactggcgta
    28081 acccttccga tctttgcccg tggcacatgg atgaaaccta cgtgaaggtc aatggccgct
    28141 gggcgtatct gtaccgggcc gtcgacagcc ggggccgcac tgtcgatttt tatctctcct
    28201 cccgtcgtaa cagcaaagct gcataccggt ttcggcactg ttgcaaatag tcggtggtga
    28261 taaacttatc atcccctttt gctgatggag ctgcacatga acccattcaa aggccggcat
    28321 tttcagcgtg acatcattct gtgggccgta cgctggtact gcaaatacgg catcagttac
    28381 cgtgagctgc aggagatgct ggctgaacgc ggagtgaatg tcgatcactc cacgatttac
    28441 cgctgggttc agcgttatgc gcctgaaatg gaaaaacggc tgcgctggta ctggcgtaac
    28501 ccttccgatc tttgcccgtg gcacatggat gaaacctacg tgaaggtcaa tggccgctgg
    28561 gcgtatctgt accgggccgt cgacagccgg ggccgcactg tcgattttta tctctcctcc
    28621 cgtcgtaaca gcaaagctgc ataccggttt ctgggtaaaa tcctcaacaa cgtgaagaag
    28681 tggcagatcc cgcgattcat caacacggat aaagcgcccg cctatggtcg cgcgcttgct
    28741 ctgctcaaac gcgaaggccg gtgcccgtct gacgttgaac accgacagat taagtaccgg
    28801 aacaacgtga ttgaatgcga tcatggcaaa ctgaaacgga taatcggcgc cacgctggga
    28861 tttaaatcca tgaagacggc ttacgccacc atcaaaggta ttgaggtgat gcgtgcacta
    28921 cgcaaaggcc aggcctcagc attttattat ggtgatcccc tgggcgaaat gcgcctggta
    28981 agcagagttt ttgaaatgta aggcctttga ataagacaaa aggctgcctc atcgctaact
    29041 ttgcaacagt gccaatttat gagtaaagga ttatgtccac gataagcacc tgggtcgatt
    29101 cctgggaggc ggccatgagg gtagggaagc gccgtcccgt caagtcagcg taatgctctg
    29161 ccagtgttac aaccaattaa ccaattctga ttagaaaaac tcatcgagca tcaaatgaaa
    29221 ctgcaattta ttcatatcag gattatcaat accatatttt tgaaaaagcc gtttctgtaa
    29281 tgaaggagaa aactcaccga ggcagttcca taggatggca agatcctggt atcggtctgc
    29341 gattccgact cgtccaacat caatacaacc tattaatttc ccctcgtcaa aaataaggtt
    29401 atcaagtgag aaatcaccat gagtgacgac tgaatccggt gagaatggca aaagcttatg
    29461 catttctttc cagacttgtt caacaggcca gccattacgc tcgtcatcaa aatcactcgc
    29521 atcaaccaaa ccgttattca ttcgtgattg cgcctgagcg agacgaaata cgcgatcgct
    29581 gttaaaagga caattacaaa caggaatcga atgcaaccgg cgcaggaaca ctgccagcgc
    29641 atcaacaata ttttcacctg aatcaggata ttcttctaat acctggaatg ctgttttccc
    29701 ggggatcgca gtggtgagta accatgcatc atcaggagta cggataaaat gcttgatggt
    29761 cggaagaggc ataaattccg tcagccagtt tagtctgacc atttcatctg taacatcatt
    29821 ggcaacgcta cctttgccat gtttcagaaa caactctggc gcatcgggct tcccatacaa
    29881 tcgatagatt gtcgcacctg attgcccgac attatcgcga gcccatttat acccatataa
    29941 atcagcatcc atgttggaat ttaatcgcgg cctcgagcaa gacgtttccc gttgaatatg
    30001 gctcataaca ccccttgtat tactgtttat gtaagcagac agttttattg ttcatgatga
    30061 tatattttta tcttgtgcaa tgtaacatca gagggcactg ttgcaaatag tcggtggtga
    30121 taaacttatc atcccctttt gctgatggag ctgcacatga acccattcaa aggccggcat
    30181 tttcagcgtg acatcattct gtgggccgta cgctggtact gcaaatacgg catcagttac
    30241 cgtgagctgc aggagatgct ggctgaacgc ggagtgaatg tcgatcactc cacgatttac
    30301 cgctgggttc agcgttatgc gcctgaaatg gaaaaacggc tgcgctggta ctggcgtaac
    30361 ccttccgatc tttgcccgtg gcacatggat gaaacctacg tgaaggtcaa tggccgctgg
    30421 gcgtatctgt accgggccgt cgacagccgg ggccgcactg tcgattttta tctctcctcc
    30481 cgtcgtaaca gcaaagctgc ataccggttt ctgggtaaaa tcctcaacaa cgtgaagaag
    30541 tggcagatcc cgcgattcat caacacggat aaagcgcccg cctatggtcg cgcgcttgct
    30601 ctgctcaaac gcgaaggccg gtgcccgtct gacgttgaac accgacagat taagtaccgg
    30661 aacaacgtga ttgaatgcga tcatggcaaa ctgaaacgga taatcggcgc cacgctggga
    30721 tttaaatcca tgaagacggc ttacgccacc atcaaaggta ttgaggtgat gcgtgcacta
    30781 cgcaaaggcc aggcctcagc attttattat ggtgatcccc tgggcgaaat gcgcctggta
    30841 agcagagttt ttgaaatgta aggcctttga ataagacaaa aggctgcctc atcgctaact
    30901 ttgcaacagt gccgatttac gtgcatagcc gattttcatt cttttctcgc taattagtta
    30961 tggggttatt gttatgttga tacagtaacg agttttgtta catgagggga gtcatttttc
    31021 gggagaagtc aggacttttc aagactgtca caaaaaccat cgtttttgat acattaattt
    31081 aaccaatagg ttgcagatca aatcgcctgt aacagccttt ctggctgttt gtcgttttca
    31141 gaagacggct gcactgaacg tcagaagccg actgcactat agcagcggag gggttggatc
    31201 catcaggcaa cgacgggctg ctgccggcca tcagcggacg cagggaggac tttccgcaac
    31261 cggccgttcg atgcggcacc gatggccttc gcgcaggggt agtgaatccg ccaggattga
    31321 cttgcgctgc cctacctctc actagtgagg ggcggcagcg catcaagcgg tgagcgcact
    31381 ccggcaccgc caactttcag cacatgcgtg taaatcatcg tcgtagagac gtcggaatgg
    31441 ccgagcagat cctgcacggt tcgaatgtcg taaccgctgc ggagcaaggc cgtcgcgaac
    31501 gagtggcgga gggtgtgcgg tgtggcgggc ttcgtgatgc ctgcttgttc tacggcacgt
    31561 ttgaaggcgc gctgaaaggt ctggtcatac atgtgatggc gacgcacgac accgctccgt
    31621 ggatcggtcg aatgcgtgtg ctgcgcaaaa acccagaacc acggccagga atgcccggcg
    31681 cgcggatact tccgctcaag ggcgtcggga agcgcaacgc cgctgcggcc ctcggcctgg
    31741 tccttcagcc accatgcccg tgcacgcgac agctgctcgc gcaggctggg tgccaagctc
    31801 tcgggtaaca tcaaggcccg atccttggag cccttgccct cccgcacgat gatcgtgccg
    31861 tgatcgaaat ccagatcctt gacccgcagt tgcaaaccct cactgatccg catgcccgtt
    31921 ccatacagaa gctgggcgaa caaacgatgc tcgccttcca gaaaaccgag gatgcgaacc
    31981 acttcatccg gggtcagcac caccggcaag cgccgcgacg gccgaggtct tccgatctcc
    32041 tgaagccagg gcagatccgt gcacagcacc ttgccgtaga agaacagcaa ggccgccaat
    32101 gcctgacgat gcgtggagac cgaaaccttg cgctcgttcg ccagccagga cagaaatgcc
    32161 tcgacttcgc tgctgcccaa ggttgccggg tgacgcacac cgtggaaacg gatgaaggca
    32221 cgaacccagt ggacataagc ctgttcggtt cgtaagctgt aatgcaagta gcgtatgcgc
    32281 tcacgcaact ggtccagaac cttgaccgaa cgcagcggtg gtaacggcgc agtggcggtt
    32341 ttcatggctt gttatgactg tttttttgta cagtctatgc ctcgggcatc caagcagcaa
    32401 gcgcgttacg ccgtgggtcg atgtttgatg ttatggagca gcaacgatgt tacgcagcag
    32461 ggcagtcgcc ctaaaacaaa gttagatgca ctaagcacat aattgctcac agccaaacta
    32521 tcaggtcaag tctgctttta ttatttttaa gcgtgcataa taagccctac acaaattggg
    32581 agttagacat catgagcaac gcaaaaacaa agttaggcat cacaaagtac agcatcgtga
    32641 ccaacagcaa cgattccgtc acactgcgcc tcatgactga gcatgacctt gcgatgctct
    32701 atgagtggct aaatcgatct catatcgtcg agtggtgggg cggagaagaa gcacgcccga
    32761 cacttgctga cgtacaggaa cagtacttgc caagcgtttt agcgcaagag tccgtcactc
    32821 catacattgc aatgctgaat ggagagccga ttgggtatgc ccagtcgtac gttgctcttg
    32881 gaagcgggga cggacggtgg gaagaagaaa ccgatccagg agtacgcgga atagaccagt
    32941 tactggcgaa tgcatcacaa ctgggcaaag gcttgggaac caagctggtt cgagctctgg
    33001 ttgagttgct gttcaatgat cccgaggtca ccaagatcca aacggacccg tcgccgagca
    33061 acttgcgagc gatccgatgc tacgagaaag cggggtttga gaggcaaggt accgtaacca
    33121 ccccatatgg tccagccgtg tacatggttc aaacacgcca ggcattcgag cgaacacgca
    33181 gtgatgccta acccttccat cgagggggac gtccaagggc tggcgccctt ggccgcccct
    33241 catgtcaaac gttatgcagc caaatcccaa caattaaggg tcttaaaatg gtaaaagatt
    33301 ggattcccat ctctcatgat aattacaagc aggtgcaagg accgttctat catggaacca
    33361 aagccaattt ggcgattggt gacttgctaa ccacagggtt catctctcat ttcgaggacg
    33421 gtcgtattct taagcacatc tacttttcag ccttgatgga gccagcagtt tggggagctg
    33481 aacttgctat gtcactgtct ggcctcgagg gtcgcggcta catatacata gttgagccaa
    33541 caggaccgtt cgaagacgat ccgaatctta cgaacaaaag atttcccggt aatccaacac
    33601 agtcctatag aacctgcgaa cccttgagaa ttgttggcgt tgttgaagac tgggaggggc
    33661 atcctgttga attaataagg ggaatgttgg attcgttgga ggacttaaag cgccgtggtt
    33721 tacacgtcat tgaagactag tcctttgcat aacaaagcca tcaaaccgga cgccagagat
    33781 tccgcgcctg ttgcgcatgg cttcgccatt ttatgcgcaa taggcgcgcc accctgtcgc
    33841 cgtttatggc ggcgttaacc caaaggagta tcgtgaaaat atcactaatg gctgcaaaag
    33901 caagaaatgg ggttattggc tgcggctcgg atatcccgtg gaacgctaaa ggtgagcagc
    33961 tgctttttaa agcaataact tacaatcaat ggctcttagt cggccgtaaa acatttgagg
    34021 caatgggggc tctcccaaat agaaagtatg cagttgtcag ccgctcagga tcggtagcta
    34081 ctaacgatga tgtggttgtg tttccatcta tagaagcagc aatgagggag ctaaagactc
    34141 ttacgaacca tgttgttgtt tctggtggtg gagagatcta caagagtctg atcgcccatg
    34201 ccgacacgct acatatctcg acaatagatt ccgagccaga gggcaatgtt ttctttccgg
    34261 aaatccccaa agagttcaat gtggtgttcg agcaggaatt tcattcaaat ataaattatc
    34321 gctatcaaat ctggcaaagg ggttaaccat ccaagccatc ggacacattt tgcttcgctg
    34381 cgctcaaaac gcaaaatgtg ccgctgctta gcggcgttag atgcactaag cacataattg
    34441 ctcacagcca aactatcagg tcaagtctgc ttttattatt tttaagcgtg cataataagc
    34501 cctacacaaa ttgggagtta gacatcatga gcaacgcagt gcccgccgag atttcggtac
    34561 agctatcaca ggcactcaac gtcatcgagc atcatctggg atcgacgttg ctggccgtgc
    34621 atttgtacgg ctctgcactc gacggtggcc tgaagccatg cagtgatatt gatttgctgg
    34681 ttactgtgac tgcacagctc gatgagactg tgcggcaggc tctgttcgta gatttcctgg
    34741 aagtttccgc ttctcccggc caaagtgaag ctctccgtgc cttggaagtt accatcgtcg
    34801 tgtacggcga tgttgttcct tggcgttatc cagccagacg ggaactgcaa ttcggggagt
    34861 ggcagcgcaa ggacattctt gcgggcatct tcgagcccgc gacaaccgat gttgatctgg
    34921 ctattctgct aactaaagca aggcaacaca gccttgcctt ggcaggttcg gccgcggaag
    34981 atttcttcaa ctcagtcccg gaaagcgatc tattcaaagc actggccgac accttgaaac
    35041 tatggaactc acaaccggat tgggcaggcg acgagcggaa tgtagtgctt actttgtctc
    35101 gcatttggta cagcgcagca accggcaaga tcgcgccgaa ggatgtagct gccaactggg
    35161 taatggaacg cctgcccgtc caacatcagc ccgtgctgct tgaagcccag caggcttacc
    35221 ttggacaagg gatggattgc ttggcctcac gcgctgatca gttgactgcg ttcatttact
    35281 ttgtgaagca cgaagccgcc agtctgctcg gctccacgcc aatgatgtct aacagttcat
    35341 tcaagccgac gccgcttcgc ggcgcagctt aattcaggcg ttagatgcac taagcacata
    35401 attgctcaca gccaaactat caggtcaagt ctgcttttat tatttttaag cgtgcataat
    35461 aagccctaca caaattggga gatatatcat gaaaggctgg ctttttcttg ttatcgcaat
    35521 agttggcgaa gtaatcgcaa catccgcatt aaaatctagc gagggcttta ctaagcttgc
    35581 cccttccgcc gttgtcataa tcggttatgg catcgcattt tattttcttt ctctggttct
    35641 gaaatccatc cctgtcggtg ttgcttatgc agtctggtcg ggactcggcg tcgtcataat
    35701 tacagccatt gcctggttgc ttcatgggca aaagcttgat gcgtggggct ttgtaggtat
    35761 ggggctcata attgctgcct ttttgctcgc ccgatcccca tcgtggaagt cgctgcggag
    35821 gccgacgcca tggtgacggt gttcggcatt ctgaatctca ccgaggactc cttcttcgat
    35881 gagagccggc ggctagaccc cgccggcgct gtcaccgcgg cgatcgaaat gctgcgagtc
    35941 ggatcagacg tcgtggatgt cggaccggcc gccagccatc cggacgcgag gcctgtatcg
    36001 ccggccgatg agatcagacg tattgcgcc
//
