LOCUS       NZ_CP057332             6790 bp    DNA     circular CON 02-APR-2024
DEFINITION  Klebsiella oxytoca strain RHB30-C02 plasmid pRHB30-C02_3, complete
            sequence.
ACCESSION   NZ_CP057332
VERSION     NZ_CP057332.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15148287
            Assembly: GCF_013826985.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella oxytoca
  ORGANISM  Klebsiella oxytoca
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6790)
  AUTHORS   AbuOun,M., Jones,H., Stubberfield,E., Gilson,D., Shaw,L.P.,
            Hubbard,A.T.M., Chau,K.K., Sebra,R., Peto,T.E.A., Crook,D.W.,
            Read,D.S., Gweon,H.S., Walker,A.S., Stoesser,N., Smith,R.P.,
            Anjum,M.F. and On Behalf Of The Rehab,Consortium.
  TITLE     A genomic epidemiological study shows that prevalence of
            antimicrobial resistance in Enterobacterales is associated with the
            livestock host, as well as antimicrobial usage
  JOURNAL   Microb Genom 7 (10) (2021)
   PUBMED   34609275
REFERENCE   2  (bases 1 to 6790)
  AUTHORS   Shaw,L.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2020) Nuffield Department of Medicine, University
            of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.7
            Assembly Name                     :: RH02 T3-C02
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 112.695489957735x
            Sequencing Technology :: Hybrid: Illumina and OXFORD_NANOPORE
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013826985.1-RS_2024_04_02
            Annotation Date                   :: 04/02/2024 04:33:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,992
            CDSs (total)                      :: 5,872
            Genes (coding)                    :: 5,778
            CDSs (with protein)               :: 5,778
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 94
            CDSs (without protein)            :: 94
            Pseudo Genes (ambiguous residues) :: 0 of 94
            Pseudo Genes (frameshifted)       :: 43 of 94
            Pseudo Genes (incomplete)         :: 59 of 94
            Pseudo Genes (internal stop)      :: 17 of 94
            Pseudo Genes (multiple problems)  :: 22 of 94
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP057332.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6790
                     /organism="Klebsiella oxytoca"
                     /mol_type="genomic DNA"
                     /strain="RHB30-C02"
                     /isolation_source="Pooled pig faecal samples collected from
                     floor of farm"
                     /db_xref="taxon:571"
                     /plasmid="pRHB30-C02_3"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
     gene            join(5997..6790,1..22)
                     /gene="sul2"
                     /locus_tag="HVY70_RS29705"
                     /old_locus_tag="HVY70_29710"
     ARG             5998..6788
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="97.42"
     gene            83..>610
                     /locus_tag="HVY70_RS29710"
                     /old_locus_tag="HVY70_29715"
                     /pseudo=""
     CDS             83..>610
                     /locus_tag="HVY70_RS29710"
                     /old_locus_tag="HVY70_29715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /name="phosphotransferase"
     gene            631..1104
                     /gene="dfrA14"
                     /locus_tag="HVY70_RS29715"
                     /old_locus_tag="HVY70_29720"
     ARG             632..1101
                     /name="dfrA14"
                     /gene="dfrA14"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA14"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <1179..1454
                     /locus_tag="HVY70_RS29720"
                     /old_locus_tag="HVY70_29725"
                     /pseudo=""
     CDS             <1179..1454
                     /locus_tag="HVY70_RS29720"
                     /old_locus_tag="HVY70_29725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase APH(3')"
                     /name="aminoglycoside phosphotransferase APH(3')"
     gene            1454..2290
                     /locus_tag="HVY70_RS29725"
                     /old_locus_tag="HVY70_29730"
     CDS             1454..2290
                     /locus_tag="HVY70_RS29725"
                     /old_locus_tag="HVY70_29730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="WP_000480968.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKP
                     IEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIA
                     AELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNA
                     SELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIA
                     QMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY"
                     /name="aminoglycoside O-phosphotransferase APH(6)-Id"
     gene            complement(<2397..2801)
                     /locus_tag="HVY70_RS29730"
                     /old_locus_tag="HVY70_29735"
                     /pseudo=""
     CDS             complement(<2397..2801)
                     /locus_tag="HVY70_RS29730"
                     /old_locus_tag="HVY70_29735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /name="IS91 family transposase"
     gene            complement(2845..3234)
                     /locus_tag="HVY70_RS29735"
                     /old_locus_tag="HVY70_29740"
     CDS             complement(2845..3234)
                     /locus_tag="HVY70_RS29735"
                     /old_locus_tag="HVY70_29740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000102614.1"
                     /translation="MSTELNSGTVGGFGHMGPNDPYNDGHSGSGSSGGSFNGGGNGGHD
                     NSSGSSYTASFGLITGRHPITVPGTKNINSVDLSAVINNIIHHEGARNNMYLDTANNVR
                     VGVTGTGWQCLATAGISAEGKRTFR"
                     /name="hypothetical protein"
     gene            3452..3892
                     /locus_tag="HVY70_RS29740"
                     /old_locus_tag="HVY70_29745"
     CDS             3452..3892
                     /locus_tag="HVY70_RS29740"
                     /old_locus_tag="HVY70_29745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011161230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005119689.1"
                     /translation="MAWHTVQETLKLTGKSRSQLYRDMAKGLVSYRTGKNDRREFETSE
                     LIRAYGELRTSETPKRHKEGHSKSVVSQAENAQLDVIQQKLDALQQTVTLMLEDKMARE
                     AENRLRNEEREQLQAEISRLADALAQEKKRGFWSRLFRSGSE"
                     /name="hypothetical protein"
     gene            complement(4659..4808)
                     /locus_tag="HVY70_RS29745"
                     /old_locus_tag="HVY70_29750"
     CDS             complement(4659..4808)
                     /locus_tag="HVY70_RS29745"
                     /old_locus_tag="HVY70_29750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001138880.1"
                     /translation="MPSEYDEQLDSTDTQLPGEYDLFDLMAQVTEENLHAPVDFGSPVG
                     REAL"
                     /name="hypothetical protein"
     gene            5379..5537
                     /locus_tag="HVY70_RS30175"
     CDS             5379..5537
                     /locus_tag="HVY70_RS30175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007772075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032287700.1"
                     /translation="MHEPPVQSDRCALSGNYQLESNPERHDKTPLAAAISNRSAREDRL
                     RGLEVEA"
                     /name="hypothetical protein"
     ARG             1455..2287
                     /name="aph(6)-Id"
                     /gene="aph(6)-Id"
                     /gene_name="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1210..1454
                     /name="APH(3'')-Ib"
                     /gene="APH(3'')-Ib"
                     /gene_name="APH(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="30.34"
     ARG             84..625
                     /name="APH(3'')-Ib"
                     /gene="APH(3'')-Ib"
                     /gene_name="APH(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.43"
                     /coverage="67.42"
     Typing          complement(4844..5017)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="99.429"
                     /coverage="100.0"
                     /evalue="1.19e-84"
     Typing          4941..5546
                     /name="rep_cluster_2335"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.593"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 agaaaccgca agaattcgtt aactgcacat tcgggatatt tctctatatt cgcgcttcat
       61 cagaaaactg aaggaacctc cattgaatcg aactaatatt ttttttggtg aatcgcattc
      121 tgactggttg cctgtcagag gcggagaatc tggtgatttt gtttttcgac gtggtgacgg
      181 gcatgccttc gcgaaaatcg cacctgcttc ccgccgcggt gagctcgctg gagagcgtga
      241 ccgcctcatt tggctcaaag gtcgaggtgt ggcttgcccc gaggtcatca actggcagga
      301 ggaacaggag ggtgcatgct tggtgataac ggcaattccg ggagtaccgg cggctgatct
      361 gtctggagcg gatttgctca aagcgtggcc gtcaatgggg cagcaacttg gcgctgttca
      421 cagcctatcg gttgatcaat gtccgtttga gcgcaggctg tcgcgaatgt tcggacgcgc
      481 cgttgatgtg gtgtcccgca atgccgtcaa tcccgacttc ttaccggacg aggacaagag
      541 tacgccgcag ctcgatcttt tggctcgtgt cgaacgagag ctaccggtgc ggctcgacca
      601 agagcgcacc gttaacccag gatgagaacc ttgaaagtat cattgatagc tgcgaaagcg
      661 aaaaacggcg tgattggttg cggtccagac ataccctggt ccgcgaaagg ggagcagcta
      721 ctttttaaag cattgaccta caatcagtgg cttctggtgg gtcgcaagac gtttgaatct
      781 atgggcgcac tccccaatag gaaatacgcg gtcgttaccc gctcaggttg gacatcaaat
      841 gatgacaatg tagttgtatt tcagtcaatc gaagaggcca tggacaggct agctgaattc
      901 accggtcacg ttatagtgtc tggtggcgga gaaatttacc gagaaacatt acccatggcc
      961 tctacgctcc acttatcgac gatcgacatc gagccagagg gggatgtttt cttcccgagt
     1021 attccaaata ccttcgaagt tgtttttgag caacacttta cttcaaacat taactattgc
     1081 tatcaaattt ggaaaaaggg ttaacaaagc tatgcaatcg acggcaaaaa gcttcgttcg
     1141 cttcgcgcac tacgcctttt tccgcgattg atagcgacga tatggttgtt tgccatggtg
     1201 atccctgcat gccgaacttc atggtggacc ctaaaactct tcaatgcacg ggtctgatcg
     1261 accttgggcg gctcggaaca gcagatcgct atgccgattt ggcactcatg attgctaacg
     1321 ccgaagagaa ctgggcagcg ccagatgaag cagagcgcgc cttcgctgtc ctattcaatg
     1381 tattggggat cgaagccccc gaccgcgaac gccttgcctt ctatctgcga ttggaccctc
     1441 tgacttgggg ttgatgttca tgccgcctgt ttttcctgct cattggcacg tttcgcaacc
     1501 tgttctcatt gcggacacct tttccagcct cgtttggaaa gtttcattgc cagacgggac
     1561 tcctgcaatc gtcaagggat tgaaacctat agaagacatt gctgatgaac tgcgcggggc
     1621 cgactatctg gtatggcgca atgggagggg agcagtccgg ttgctcggtc gtgagaacaa
     1681 tctgatgttg ctcgaatatg ccggggagcg aatgctctct cacatcgttg ccgagcacgg
     1741 cgactaccag gcgaccgaaa ttgcagcgga actaatggcg aagctgtatg ccgcatctga
     1801 ggaacccctg ccttctgccc ttctcccgat ccgggatcgc tttgcagctt tgtttcagcg
     1861 ggcgcgcgat gatcaaaacg caggttgtca aactgactac gtccacgcgg cgattatagc
     1921 cgatcaaatg atgagcaatg cctcggaact gcgtgggcta catggcgatc tgcatcatga
     1981 aaacatcatg ttctccagtc gcggctggct ggtgatagat cccgtcggtc tggtcggtga
     2041 agtgggcttt ggcgccgcca atatgttcta cgatccggct gacagagacg acctttgtct
     2101 cgatcctaga cgcattgcac agatggcgga cgcattctct cgtgcgctgg acgtcgatcc
     2161 gcgtcgcctg ctcgaccagg cgtacgctta tgggtgcctt tccgcagctt ggaacgcgga
     2221 tggagaagag gagcaacgcg atctagctat cgcggccgcg atcaagcagg tgcgacagac
     2281 gtcatactag atatcaagcg acttctccta tcccctggga acacatcaat ctcaccggag
     2341 aatatcgctg gccaaagcct tagcgtagga ttccgcccct tcccgcaaac gaccccaaac
     2401 aggaaacgca gctgaaacgg gaagctcaac acccactgac gcatgggttg ttcaggcagt
     2461 acttcatcaa ccagcaaggc ggcactttcg gccatccgcc gcgccccaca gctcgggcag
     2521 aaaccgcgac gcttacagct gaaagcgacc aggtgctcgg cgtggcaaga ctcgcagcga
     2581 acccgtagaa agccatgctc cagccgcccg cattggagaa attcttcaaa ttcccgttgc
     2641 acatagcccg gcaattcctt tccctgctct gccataagcg cagcgaatgc cgggtaatac
     2701 tcgtcaacga tctgatagag aagggtttgc tcgggtcggt ggctctggta acgaccagta
     2761 tcccgatccc ggctggccgt cctggccgcc acatgaggca tgttccgcgt ccttgcaata
     2821 ctgtgtttac atacagtcta tcgcttagcg gaaagttctt ttaccctcag ccgaaatgcc
     2881 tgccgttgct agacattgcc agccagtgcc cgtcactccc actcttacat tgttcgcagt
     2941 atctaggtac atgttattgc gtgcaccttc atgatgtata atgttattaa tgacagcaga
     3001 aagatcgaca gaattaatat tcttcgtacc tgggacagtt atcgggtgtc ggccagtgat
     3061 gagaccaaag gatgcagtat aagatgaacc actactatta tcatggccac cattaccacc
     3121 accgttaaaa ctacctcccg aacttccaga gccgctatga ccatcattgt aggggtcatt
     3181 tggtcccatg tgaccaaaac caccgacagt accgctattt aactctgtac tcataaaatt
     3241 atcctctttg acttttaaaa acagcaaaaa ctgtatttat aacaatgtgt ttatatacag
     3301 tattcgaaat actacgcccg tcaaaaccac accgtcaaca ggttttttgt gtatttttca
     3361 cgcctcacgg gcagcctcag accttttgtg ttaaaacagt aatatgttct gctgttacaa
     3421 tacggtacac acaggagaca ctgtcacttt tatggcatgg cacacagttc aagagacact
     3481 gaaattaaca ggaaagtcgc gctcgcaatt atatcgtgac atggctaaag gccttgtcag
     3541 ctatcgcaca ggaaaaaatg atcgccggga gttcgagacc agtgaactga ttcgggccta
     3601 tggcgagctg cgcacttctg agacaccaaa aaggcacaag gagggacact ccaaatctgt
     3661 cgttagccag gcggaaaatg ctcagctaga cgtcattcag cagaaactgg acgctctgca
     3721 gcagactgtt accctaatgc ttgaagacaa gatggcgcgg gaagcagaaa accgcctgcg
     3781 aaatgaggag agggaacaac tacaggccga aattagccgt ctggctgacg cgctggcaca
     3841 ggaaaaaaag cggggattct ggtcgcggct gtttcgctcc ggttcagagt aacagtgcag
     3901 gtgactctga tttaccataa catctgttat cagcaccgcc tgagaggccc tcagggcgtt
     3961 tctgacggga aaccggtaaa acaggcaaca aaccacccga aaacccgcca gaaacgcgca
     4021 ggctctgttt ttacggcatg catgagtatg cgcacaagtg catagcgcgg aaattcacac
     4081 cattcagccg gggtaagtcc tgtttccggc gttcttccca tccgaaaacg gtgaacgggg
     4141 acgcaattta ttgcgtggcc gtgaagcgtt gccggcgcag ccggaaaacc cgctgtcagc
     4201 acgttcagga agggggtgat gtacaaatgg cacagaggat gaaagtgacg tatgagctga
     4261 aggaatgatg taaaagtgat gtataagtga tgtaaaagcg atgtataagt gatgtaaaag
     4321 tgatgtatga actgaaggag cgatgtaatt ctgtagtcag gaagaataac ccgttcatgc
     4381 aggcatgaac gatacagtga ggaacgcttt ttttgtcacg atctcccctt aacctgcgta
     4441 aatcacccgc catggttgat tatttttcaa cctcaaaatg gtcatacacc taacgcagcc
     4501 gcgattttca tcgcaactgc atgaattaaa agaaaaaaaa ggaatatttc gttttcacga
     4561 gtaatacccg ggtattaaaa atccactgta attacatgaa aataaagaaa taaaaggtaa
     4621 taccggagta ttaccacgta cgcgggcaag cgaaaaagct ataacgcttc ccggccgaca
     4681 ggcgacccaa aatccacagg ggcatgcagg ttctcttcag taacctgcgc cattaaatca
     4741 aaaaggtcat attcgccggg aagctgcgta tcagtcgaat ccagttgttc atcatattca
     4801 gatggcatgg ggtgatatcc agtagctgag aggttgttag cgggtttcgg ggcgcagccc
     4861 tgaaccagtc atgtagcgct agcggagtgt atactggctt actatgttgc cacgattgcg
     4921 aaaatcagtg aagtgcttca tgtggcagga gaaaaaaggc agcaccggcg cgtcagcaga
     4981 atatgcgata caggagatat tccgcttcct cgctcactga ctcgctacgc tcggtcgttc
     5041 ggctgcggcg agcggtaccg gcttacggac ggggacggaa atttcctgga agataccagg
     5101 aagacactta gcaaagaaga gataaggcca cggcgaagcc gtttttccat aggctccgcc
     5161 cccctgacaa gcatcgcaaa atctgacgct caaatcagtg gtggcgaaac ccgacaggac
     5221 tataaagatc ccaggcgttt ccccctggta gctccctcgt gcgctctcct gttcctgcct
     5281 ttcggtttac cggtgtcatt ccgctgttat ggccgcggtt tctcattcca cgcctgacac
     5341 tcagttccgt gaaggcagtt cgctccaagc tggactgtat gcacgaaccc cccgttcagt
     5401 ccgaccgctg cgccttgtcc ggtaactatc aacttgagtc caacccggaa agacacgaca
     5461 aaacgccact ggcagcagcc attagtaaca ggagtgcacg agaagataga ttaagaggtc
     5521 ttgaagtaga ggcctgactg cggctacact gaaagaacag ttttggtaat ggcggtctcg
     5581 tgaaccctgt taccgggtta agcagttccc caactgactt aaccttcgaa caaaccgcct
     5641 ccccaggcgg ttttttcgtt tacagagcaa gagattacga ttcattgaaa aggatctcaa
     5701 gaagatcctt tgtagattac tatcaattaa tcttccgaac atgacaccag tcactgttga
     5761 ttacggttaa accgctccgt aacaggtttc cctcgtattg gtgacttgca gcaccaaaga
     5821 agcaaaaaag ataaatatat ctacttattg agagatgata tatttatttc caaaatgcta
     5881 cagatacatc atcatgaaac ggatcaccgc aaacaggtta ctcgcctggg gattcccttt
     5941 cgacccgagc atccgtatga gactcatgct cgattattat tattatagaa gcccccatga
     6001 ataaatcgct catcattttc ggcatcgtca acataacctc ggacagtttc tccgatggag
     6061 gccggtatct ggcgccagac gcagccattg cgcaggcgcg taagctgatg gccgaggggg
     6121 cagatgtgat cgacctcggt ccggcatcca gcaatcccga cgccgcgcct gtttcgtccg
     6181 acacagaaat cgcgcgtatc gcgccggtgc tggacgcgct caaggcagat ggcattcccg
     6241 tctcgctcga cagttatcaa cccgcgacgc aagcctatgc cttgtcgcgt ggtgtggcct
     6301 atctcaatga tattcgcggt tttccagacg ctgcgttcta tccgcaattg gcgaaatcat
     6361 ctgccaaact cgtcgttatg cattcggtgc aagacgggca ggcagatcgg cgcgaggcac
     6421 ccgctggcga catcatggat cacattgcgg cgttctttga cgcgcgcatc gcggcgctga
     6481 cgggtgccgg tatcaaacgc aaccgccttg tccttgatcc cggcatgggg ttttttctgg
     6541 gggctgctcc cgaaacctcg ctctcggtgc tggcgcggtt cgatgaattg cggctgcgct
     6601 tcgatttgcc ggtgcttctg tctgtttcgc gcaaatcctt tctgcgcgcg ctcacaggcc
     6661 gtggtccggg ggatgtcggg gccgcgacac tcgctgcaga gcttgccgcc gccgcaggtg
     6721 gagctgactt catccgcaca cacgagccgc gccccttgcg cgacgggctg gcggtattgg
     6781 cggcgctgaa
//
