LOCUS       NZ_CP057231            32364 bp    DNA     circular CON 01-APR-2024
DEFINITION  Escherichia fergusonii strain RHB32-C16 plasmid pRHB32-C16_3,
            complete sequence.
ACCESSION   NZ_CP057231
VERSION     NZ_CP057231.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15148320
            Assembly: GCF_013820225.1
KEYWORDS    RefSeq.
SOURCE      Escherichia fergusonii
  ORGANISM  Escherichia fergusonii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32364)
  AUTHORS   AbuOun,M., Jones,H., Stubberfield,E., Gilson,D., Shaw,L.P.,
            Hubbard,A.T.M., Chau,K.K., Sebra,R., Peto,T.E.A., Crook,D.W.,
            Read,D.S., Gweon,H.S., Walker,A.S., Stoesser,N., Smith,R.P.,
            Anjum,M.F. and On Behalf Of The Rehab,Consortium.
  TITLE     A genomic epidemiological study shows that prevalence of
            antimicrobial resistance in Enterobacterales is associated with the
            livestock host, as well as antimicrobial usage
  JOURNAL   Microb Genom 7 (10) (2021)
   PUBMED   34609275
REFERENCE   2  (bases 1 to 32364)
  AUTHORS   Shaw,L.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2020) Nuffield Department of Medicine, University
            of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.7
            Assembly Name                     :: RH13 T3-C16
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.84135526264x
            Sequencing Technology :: Hybrid: Illumina and OXFORD_NANOPORE
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013820225.1-RS_2024_04_01
            Annotation Date                   :: 04/01/2024 04:17:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,694
            CDSs (total)                      :: 4,578
            Genes (coding)                    :: 4,454
            CDSs (with protein)               :: 4,454
            Genes (RNA)                       :: 116
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 48 of 124
            Pseudo Genes (incomplete)         :: 64 of 124
            Pseudo Genes (internal stop)      :: 28 of 124
            Pseudo Genes (multiple problems)  :: 18 of 124
            Pseudo Genes (short protein)      :: 2 of 124
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP057231.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..32364
                     /organism="Escherichia fergusonii"
                     /mol_type="genomic DNA"
                     /strain="RHB32-C16"
                     /isolation_source="Pooled sheep faecal samples collected
                     from floor of farm"
                     /db_xref="taxon:564"
                     /plasmid="pRHB32-C16_3"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
     gene            1..855
                     /locus_tag="HVZ03_RS23005"
                     /old_locus_tag="HVZ03_22995"
     CDS             1..855
                     /locus_tag="HVZ03_RS23005"
                     /old_locus_tag="HVZ03_22995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001239324.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001239324.1"
                     /translation="MRLQVKTVTGLTKVRHRNEVGVTLASLSLSAKRVLFLALCQIDTK
                     EMLNDDILEVDADFFSKTTTLDKYAAYAALKEGAKVLASTTLVLNRDDLKTLSNELGIS
                     TSKNKIPDRLDLNLTEFCAYYDHLATVRIKFTNTAKRYFSKLIGSENRYTTQVLKSVVI
                     LNSVNSTNLYQVIRKYYSLNPASKSFEISVDQLKEEMGLYNIENGEKVYRYPKYSFFIR
                     DVINKSIREIIEKTEIRDIKFSVAGKKGRMVHMLRFDFSLNEDISLSDDEAKFLEEFDK
                     KVL"
                     /name="replication initiation protein"
     gene            880..1326
                     /locus_tag="HVZ03_RS23010"
                     /old_locus_tag="HVZ03_23000"
     CDS             880..1326
                     /locus_tag="HVZ03_RS23010"
                     /old_locus_tag="HVZ03_23000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021532249.1"
                     /translation="MAKIYQFPQGEERAKFRKEIAKERKKRFAVKTGSTFVKWLGWGWF
                     YLRLLVASVLHFIFVFVLAILGAFKWAVFWLGGILCVITWYHLDHQLWTPQNLTIPVIT
                     ATWILGLLAEPLMELLNKTMPWHKLLVPEPADESTENSSEISQQ"
                     /name="hypothetical protein"
     gene            1394..1819
                     /gene="ddp1"
                     /locus_tag="HVZ03_RS23015"
     CDS             1394..1819
                     /gene="ddp1"
                     /locus_tag="HVZ03_RS23015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_179893738.1"
                     /translation="MTSLTPFRNVCPVTYSRFLLENFMKYQVREFINEKYAKAVNLLKD
                     NLKENYHVFYGVRLSEILFPASEYGTDAFFKEFESINSVILPLVIFDLIQRKPMMIISF
                     DKILDASLLEGTNIVVLECTTLADLLTNDNIDSLYKS"
                     /name="ddp1"
     gene            complement(1816..2793)
                     /locus_tag="HVZ03_RS23020"
                     /old_locus_tag="HVZ03_23010"
     CDS             complement(1816..2793)
                     /locus_tag="HVZ03_RS23020"
                     /old_locus_tag="HVZ03_23010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6685 family protein"
                     /protein_id="WP_012301151.1"
                     /translation="MRYLTELICKLYRLTDHHKLTAATFKNLADIKLVEPTADADTILQ
                     LENIFSEYSLRYIDRDLAEILSNIITTDKNHSLDFDFNKIQSLTASKSFGCGWNKVING
                     SWFKNLYSWGEGMYPAQNLKAENISDWEDNIWHIEHEGFNPRDPINVKYYSWLDRYVAL
                     NSGGSHHAAMVVYQSVRDKLEYKREAVIEQLSINSNTVEILGQNYYSFIFQIKHPSNKT
                     ENYTSEYEFTDALKDFGQNRHTTLKPVNYVSNIKLAFIPKDALKTNSETFRNWFYSAIS
                     YGKIISLPDYLKNPAHYHTLHYSHEVDSITLGDPSRKYKLKGDS"
                     /name="DUF6685 family protein"
     gene            complement(2818..3099)
                     /locus_tag="HVZ03_RS23025"
                     /old_locus_tag="HVZ03_23015"
     CDS             complement(2818..3099)
                     /locus_tag="HVZ03_RS23025"
                     /old_locus_tag="HVZ03_23015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_058805671.1"
                     /translation="MALKLNRPNIDESKQPATNAETARFISGATRAPVVGKPKLMNFRL
                     SAHFEDILEAEAIRTGQSKTTVLKAALAMYNSQDENIKNHWLLESAKF"
                     /name="hypothetical protein"
     gene            complement(3199..3861)
                     /locus_tag="HVZ03_RS23030"
                     /old_locus_tag="HVZ03_23020"
     CDS             complement(3199..3861)
                     /locus_tag="HVZ03_RS23030"
                     /old_locus_tag="HVZ03_23020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516402.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHDL
                     LSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVSDI
                     VVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDLDKL
                     LRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIGIL"
                     /name="division plane positioning ATPase MipZ"
     gene            4242..4886
                     /locus_tag="HVZ03_RS23035"
                     /old_locus_tag="HVZ03_23025"
     CDS             4242..4886
                     /locus_tag="HVZ03_RS23035"
                     /old_locus_tag="HVZ03_23025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001503708.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000203199.1"
                     /translation="MTSNAPTNFVRAYLRASTAEQDASRALETIEAFARERGLIICSYY
                     IENESGSRLDRPELFRLLRDCQQNDILLIEDVDRLSRLSGEDWNTLKKMIRQKDIRVMA
                     VNVPTTWINSGMSEFDSRLFAAINDMLLDMLAAVARRDYEQRRERQKQGIEKARKDGKY
                     KGRKPNQARHDAIIRLIESGSSWTQVQKVLGCSRGTISSAIKRKSLQSSGE"
                     /name="recombinase family protein"
     gene            complement(5002..5181)
                     /locus_tag="HVZ03_RS23040"
                     /old_locus_tag="HVZ03_23030"
     CDS             complement(5002..5181)
                     /locus_tag="HVZ03_RS23040"
                     /old_locus_tag="HVZ03_23030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000347020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000347021.1"
                     /translation="MDFMSILGRCLLLPFPVAMFVGCLFPGIDDRFTGMFMSFIVGCLS
                     WYITKPKPQKAEVA"
                     /name="hypothetical protein"
     gene            complement(5248..5343)
                     /gene="dqlB"
                     /locus_tag="HVZ03_RS23645"
     CDS             complement(5248..5343)
                     /gene="dqlB"
                     /locus_tag="HVZ03_RS23645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_000609146.1"
                     /translation="MINLLIIVLRAVAALANALIAVLELIRQFID"
                     /name="dqlB"
     gene            complement(5904..5987)
                     /gene="dqlB"
                     /locus_tag="HVZ03_RS23650"
     CDS             complement(5904..5987)
                     /gene="dqlB"
                     /locus_tag="HVZ03_RS23650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_272056275.1"
                     /translation="MMNLLIIVLRAVLAIANALIAIQKLIE"
                     /name="dqlB"
     gene            6714..7505
                     /locus_tag="HVZ03_RS23045"
                     /old_locus_tag="HVZ03_23035"
     CDS             6714..7505
                     /locus_tag="HVZ03_RS23045"
                     /old_locus_tag="HVZ03_23035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEPN domain-containing protein"
                     /protein_id="WP_000501395.1"
                     /translation="MGATKDWVMQVEESRREEWIRERLSSPDLEEDSEEWQLLEKDYDE
                     YQDFLSDMAMEEYENEKWLKQHPHTEIYKIAINLLEQIKEEGKQSTSEVFIKMKIAYIV
                     TIMENCLSEMIKSVVLSHNRYVENAIRNINELKAKNISLSELINKESNANKYVQEYLSD
                     ILYHRIQLVVEIYKAVLQPKQYPRFPLKNINELMKLRHDIVHRNGKTKTTDEKIHTFNT
                     ATLNDAFKVVEEFLNNMMNLISDAVEHHENEQIARDLEDEF"
                     /name="HEPN domain-containing protein"
     gene            7556..8881
                     /locus_tag="HVZ03_RS23050"
                     /old_locus_tag="HVZ03_23040"
     CDS             7556..8881
                     /locus_tag="HVZ03_RS23050"
                     /old_locus_tag="HVZ03_23040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEPN domain-containing protein"
                     /protein_id="WP_058805679.1"
                     /translation="MATKKYELTKEYFFHGEFWHQLDDNKGRFSARIEYSPYHGLILDY
                     CISDSESPRTCEILYGVLNTGERCTLIGKFDFTQGNIHFDKGIIHTGRHGFPIMLFNDF
                     YAPDSKIEYCDLSLHGLQEFIHPHGFFTQLKHLEHPIFIAKGNHWTLQLVNHVSFSVIG
                     DDLLNIINCQNKAALENIIHQLKKTKELYPDAFFSIRKELVFYFRIKSSNDLGIKDHIS
                     KCWDISGLFSILLNKPTLPEEINIKFKGNGSKTPCLLTTGFEQRTIDLALREIKHQLLP
                     INRKHINLGKIFCKWFKIAERYMPLTITYQYETGFRTLHQAHTDIILFATQLEAINKTI
                     GGSKNEKYMKPINEYASLFLIQEIEMFFKKFNNKSIGENIATLRNELAHVDRKKELMNI
                     LTIGDYVKIGNYLKTIVTSYLLSDLGINNIIIEKYQAQTIQE"
                     /name="HEPN domain-containing protein"
     gene            complement(9057..9320)
                     /locus_tag="HVZ03_RS23055"
                     /old_locus_tag="HVZ03_23045"
     CDS             complement(9057..9320)
                     /locus_tag="HVZ03_RS23055"
                     /old_locus_tag="HVZ03_23045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001714223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072657.1"
                     /translation="MSNTSYKQIIPATDWYFRHDNVSGVAGKSTVYQLAAWALKENGEV
                     VGLVTVRDDNGRPKLVTPPPVPGDYLHKEQLTDDEKEWAKRR"
                     /name="hypothetical protein"
     gene            complement(9371..9832)
                     /locus_tag="HVZ03_RS23060"
                     /old_locus_tag="HVZ03_23050"
     CDS             complement(9371..9832)
                     /locus_tag="HVZ03_RS23060"
                     /old_locus_tag="HVZ03_23050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293131.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293131.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERAERERKRQELLQLIAGEGFSPEELLGLSEEAPKSRKKTLPKAPP
                     KYQFEENGETKYWSGRGRAPKPIDEALKAGRSLEDFRINKSLNGVTDEQ"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(9848..10054)
                     /gene="hha"
                     /locus_tag="HVZ03_RS23065"
                     /old_locus_tag="HVZ03_23055"
     CDS             complement(9848..10054)
                     /gene="hha"
                     /locus_tag="HVZ03_RS23065"
                     /old_locus_tag="HVZ03_23055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            complement(10051..12204)
                     /locus_tag="HVZ03_RS23070"
                     /old_locus_tag="HVZ03_23060"
     CDS             complement(10051..12204)
                     /locus_tag="HVZ03_RS23070"
                     /old_locus_tag="HVZ03_23060"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_058805673.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVLRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSSRKSKAFNSAKVTAHTAIIPTSSVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAEITDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVVVNEKKTTPLPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPNM
                     TALWSEKQTAIENGDLTVEQFINELYGELTGMISDVDLGKMKIEPAAPAGQFQHLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            complement(12209..12784)
                     /locus_tag="HVZ03_RS23075"
                     /old_locus_tag="HVZ03_23065"
     CDS             complement(12209..12784)
                     /locus_tag="HVZ03_RS23075"
                     /old_locus_tag="HVZ03_23065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_058805675.1"
                     /translation="MQYALFDGMERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     VCYGGYLLNPDVSDLDISRKIKDQTGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKDQDIATNILNREGIFAFNGCEHRFRQ
                     PVSEDNWQQAVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            complement(12788..>12970)
                     /locus_tag="HVZ03_RS23570"
                     /pseudo=""
     CDS             complement(12788..>12970)
                     /locus_tag="HVZ03_RS23570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            complement(13083..13385)
                     /locus_tag="HVZ03_RS23080"
                     /old_locus_tag="HVZ03_23070"
     CDS             complement(13083..13385)
                     /locus_tag="HVZ03_RS23080"
                     /old_locus_tag="HVZ03_23070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000820907.1"
                     /translation="MKRICKGLIVIFTVSCFIAPTYAADPCKSVFCLYGKAVGSSGGSE
                     CSSAEKDFFKNVEKKKGKIRWGKTFDLRKNFLNQCSTADPAAISLIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(13382..13795)
                     /locus_tag="HVZ03_RS23085"
                     /old_locus_tag="HVZ03_23075"
     CDS             complement(13382..13795)
                     /locus_tag="HVZ03_RS23085"
                     /old_locus_tag="HVZ03_23075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_012477153.1"
                     /translation="MKKILMISILVLTACSSPPEPPQVEWEKRPEVMNTQIMNWKPTSG
                     VIKSNNINSSWSKVLPDFKPENHLYDDSVFYAVAHSEKIVVRTSSFDSYWSAKDWLRKN
                     GATGVIEYQPLKRWLNNDYVEIYLSRINIQRLL"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(13792..15627)
                     /locus_tag="HVZ03_RS23090"
                     /old_locus_tag="HVZ03_23080"
     CDS             complement(13792..15627)
                     /locus_tag="HVZ03_RS23090"
                     /old_locus_tag="HVZ03_23080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053816.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_024159713.1"
                     /translation="MSLKLPDKGQWVFIGLVMCLVTYYTGSVAVYFLNGKTPLYIWKNF
                     DSMLLWRIITESNIRTDIRLTAIPSLLSGMVSSLIVPVFIIWQLNKTAVALYGDAKFAS
                     DNDLRKSKLLKWEKENDTDILVGAYKGKYLWYTAPDFVSLGAGTRAGKGAAIGIPNLLV
                     RKHSLIALDPKQELWKITSKVREILLGNKVYLLDPFNSKTHQFNPLFYIDLKAESGAKD
                     LLKLIEILFPSYGMTGAEAHFNNLAGQYWTGLAKLLHFFINYEPSWLNEFGLKPVFSIG
                     SVVDLYSNIDRELILSKREELEGTNGLDENALYHLRDALTKIREYHETEDEQRSSIDGS
                     FRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAEDISLAYDFLNLFFNFVVE
                     VTLRENPDFDPTLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNE
                     IYGIEGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGYITTTSKSTSKNRGRSTSQGESE
                     SEARRALVLPQELGTLDFKEEFIILKGENPVKAEKALYYLDPYFMDRLMKVSPKLASLT
                     MKLNKTKKIFGVKGLKYPSKEKMLSVGELESEVLL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            complement(15630..16661)
                     /gene="virB11"
                     /locus_tag="HVZ03_RS23095"
                     /old_locus_tag="HVZ03_23085"
     CDS             complement(15630..16661)
                     /gene="virB11"
                     /locus_tag="HVZ03_RS23095"
                     /old_locus_tag="HVZ03_23085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058463.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_001058474.1"
                     /translation="MNNENRHLIYDVVNDYFYHWLNEIEGVTEIAVNRPGEIFIKVRGK
                     WQWYEQKMSYSDCLSFASTLADFHDGGSVTPEYPLRSATLPGGERVQVVIPPATEKDTV
                     SITIRKPSGIFISHDKFIKQGFYSRVSGLSGDSVMEDNISALITSGYFDRVIPESLRQG
                     KTIVFCGGTGSGKTTFANACLEYIPHHLRCISIEDTDEAKFRFHKNHVKLYYPAEGESK
                     VITSASLLRSCFRMNPDRILMTEIRGAEAWDFLKASSSGHAGNITTVHESSPEYAVLGI
                     VQRCYMNPECQNLPFNVILRRVLSNIDIIMSIKYLDDEDFRFASGIYYKQLHFDDYFRK
                     LKE"
                     /name="virB11"
     gene            complement(16663..17868)
                     /gene="virB10"
                     /locus_tag="HVZ03_RS23100"
                     /old_locus_tag="HVZ03_23090"
     CDS             complement(16663..17868)
                     /gene="virB10"
                     /locus_tag="HVZ03_RS23100"
                     /old_locus_tag="HVZ03_23090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001378527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_058805665.1"
                     /translation="MTEQENKIPTATEIEQQLRERRQKELEQAGKTPEEEPGKPALQLG
                     IEKLKKSRKGMIILVVGFLLLAAGVSVYYIPSIIRSVSSGDEKPASQPLATGAAKRQTG
                     LSEDIDPFNTAQKKTEKPEEEKVISSEKTEPPENKQQSFSRALDVSLDGSQTGNSSSSA
                     GTSVSHTAASEPESDKKDEAKATAQTTESAPLAKITKLPYDPNLFIPEGTSIPCSLDRR
                     FVSDLAGKLECTVNSDIYSASGNVKLIERGTAAKLMYKAGSLNHGQGRVFVMAYKLRTR
                     SKPFIDIPLVDSQAAGALGEAGASGWIDTHFSERFLGAMMVGMIPDLSQAASGIAQNNR
                     DSQTDYTANSRQAFADIAREAFSNSVNIPPTLYKNQGEIITLIVGQDLDFSGIYKLKMK
                     GG"
                     /name="virB10"
     gene            complement(17865..18794)
                     /locus_tag="HVZ03_RS23105"
                     /old_locus_tag="HVZ03_23095"
     CDS             complement(17865..18794)
                     /locus_tag="HVZ03_RS23105"
                     /old_locus_tag="HVZ03_23095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000783379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_001722388.1"
                     /translation="MKMNKGALIMALLMAAHVCHAAVLPSGSRFDPRNQIVSYNPNNTT
                     IINSAVGYTTTLVFDEDETVISARTGFPQGWAVNKEDNLVYLEVRPVKQTVQKNNMDEN
                     GNTSSESVSVALDPENELERWRTNLFVRTTKRNYSMELNARTFRQPEKIAFVVNYQYPQ
                     ERRKEQAEIEKKRTEALARRQEEQAINRSLENAKSPRNWQYWKRVAEGSQDISPDYAYD
                     DGRYTWFGFSQLKKIPSVFVMNGMQETLTNPVIKQSGSFTVVGVPVDKRFVLRLGEQVV
                     GIENQGFGKVRLPAGDTVSPDVKKEVIQ"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            complement(18799..19512)
                     /locus_tag="HVZ03_RS23110"
                     /old_locus_tag="HVZ03_23100"
     CDS             complement(18799..19512)
                     /locus_tag="HVZ03_RS23110"
                     /old_locus_tag="HVZ03_23100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_052909228.1"
                     /translation="MEFKLPGFKNKKDVTDSSVSFEEKNIALQERMNRIYKFGGIGGML
                     IGGLSLLALNAALPLKTTVVDAYLIDKVTGVAERLTSVKKEHLSENEAIARYFITQYIK
                     HREGYNFFSLQHDYDYVMAYSAENVAADYNALFNSEQAPKLVYNKAEKTAMVQDNPSVI
                     ISPSSRADDKDIGAYIRFRLTIRDVATGQTRQEFWNVRLTYRIEPQVEMVSGERNNNPL
                     KFVVTSYVRDKEARG"
                     /name="type IV secretion system protein"
     gene            complement(19758..20819)
                     /locus_tag="HVZ03_RS23115"
                     /old_locus_tag="HVZ03_23105"
     CDS             complement(19758..20819)
                     /locus_tag="HVZ03_RS23115"
                     /old_locus_tag="HVZ03_23105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000796673.1"
                     /translation="MAEASNFFVTAKEEILSVLDASVSGQLTSLSNIAGTLGRYGVSIY
                     VLWYAFTVLARKQQTPVPDFIWNLCRFSIILMFVQNAGGWLNTSLVAIDGLKDSLSGNN
                     DAWLWLDQLWTKVQQVAAHVMSKDTSTYVKTDGAIAALFTYFGGILALVACAIVFLAAE
                     VTLKLLTVTAPVFIFCLMFGFLRQMFNSWLQLIFSSCLIFMFGSLALRAGTSFLNIVLS
                     LAIDTVDNRNLIKIGATAAVAGIFMAWIIWQAKSYASQIAGVGVEGAMQGAAAMGIGAG
                     VFGASRMARGALGMGRNAGIGAWKGLRRQEGGFGQSPGITGKTANLAGQGVNIGAKKLR
                     QAAIERAKKMYGG"
                     /name="type IV secretion system protein"
     gene            complement(20831..21115)
                     /locus_tag="HVZ03_RS23120"
                     /old_locus_tag="HVZ03_23110"
     CDS             complement(20831..21115)
                     /locus_tag="HVZ03_RS23120"
                     /old_locus_tag="HVZ03_23110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_001722385.1"
                     /translation="MKKSFVLIGALSIFSLVGCEETKSVDWWLEHHEESLKKEAECKKT
                     GSDNQNCRNVKEANFRYQQLHAKEPNFKEYFKKYKDASNHEEKGDMPKK"
                     /name="EexN family lipoprotein"
     gene            complement(21130..21879)
                     /locus_tag="HVZ03_RS23125"
                     /old_locus_tag="HVZ03_23115"
     CDS             complement(21130..21879)
                     /locus_tag="HVZ03_RS23125"
                     /old_locus_tag="HVZ03_23115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001722384.1"
                     /translation="MKKQIMAAFVASLIVISGAQAGIPVAIDANPEWAIEAGRWTERLK
                     QWAETVKHYESQINAYKQELLSKTGIRDVQGLVQSAQSVSKELMQIYDQGNAFIDDYIK
                     NPEGALSEQAKSLLSDYKVTDTCHNLGYSGDLVRGCEATFLSQLASVEYGNKLESKLRQ
                     DNQTMKDLIDQVKNAKDTKATQDATNAVALEQLKFEKLKFQYQMYRDKQRDLAEYKEKM
                     AQAAFRKQQLEAEEPSFKDAARRYTLN"
                     /name="type IV secretion system protein"
     gene            complement(21890..24643)
                     /locus_tag="HVZ03_RS23130"
                     /old_locus_tag="HVZ03_23120"
     CDS             complement(21890..24643)
                     /locus_tag="HVZ03_RS23130"
                     /old_locus_tag="HVZ03_23120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_065314228.1"
                     /translation="MSTLFKGLTRPALIRGLGVPLYPFLGMCIICVLLGVWIHEAMYAL
                     ILPGWYAIRRVTQFDERFFDLLYLRTLVKGHPLSNKRFSAVHYAGSQYNEVDISKVDNF
                     MKLKDQSSVEELIPYSSHITDNIIVTKNRDLLATWQIDGAYFECVDSEDLSILTDQLNT
                     LIRSFEGKSVTLYPHRIRCKKGVRPVFNSKIPFVNRVMNDYYESFPQSEFFENKLFLTI
                     CFKPFTTEDKVTHFFSRSKKQKDIFKEPVNEMNEICDRLNTYLSRFHSRRLGLYEDHGV
                     VYSDQLSLFQYLLSGRWQKVRVSSSPFYTYLGGKDLFFGNDAGQITASDHARYFRCIEI
                     KDYFQETDAGILDALMYLPVEYVVTSSFTAMDKQSAIKALDDQIDKLEMTDDAAKSLLA
                     DLKVGLDMVSSGYISFGKSHQTLVVFADSPERLVKDTNIVTSTLEDLGLIVTYSTLSLG
                     AAYFAQLPGNYTLRPRLSTLSSLNFAEMESFHNFFSGKEKGNTWGEKLITLRGSGNDIY
                     HLNYHMTTEHQNFFGKNPTLGHTEILGTSNVGKTVLLMTKAFAAQQFGTPESFPANRKL
                     KKLTTVFFDKDRAGEVGIRAMGGSYYRVKEGEPTGWNPAALPPTKRNIAFMKDLVRLLC
                     TLNSEPLDDYQNSLISDAVERLMQRSDRSYPVSKLRPLIQEPDDTETKRHGLKARLKPW
                     TQGEEFGWVFDNREDTFDVDNLDVFGIDGTEFLDNKVLASAASFYLIYRVTMLADGRRL
                     LIYMDEFWQWINNEAFRDFVYNKLKTGRKLDMVLVVATQSPDELIKSPIAAAVREQCAT
                     HIYLANPKAKRSEYVDGLQVRELYFDKIKAIDPLSRQFLVVKNPQRKGESDDFAAFARL
                     ELGKAAYYLPVLSASKPQLELFDEIWKEGMKPEEWLDTYLEQANLI"
                     /name="VirB3 family type IV secretion system protein"
     gene            complement(24662..24958)
                     /locus_tag="HVZ03_RS23135"
                     /old_locus_tag="HVZ03_23125"
     CDS             complement(24662..24958)
                     /locus_tag="HVZ03_RS23135"
                     /old_locus_tag="HVZ03_23125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000916182.1"
                     /translation="MLKLNLNKRYLTLSLFMAALMLCVAEPAFADDVSTKTTGFLQKII
                     DFLTDIRKPAITIIALVIGYIAIFSRQHTSWIVPLVIGIIIFIVAPYIPDWLA"
                     /name="TrbC/VirB2 family protein"
     gene            complement(24936..25583)
                     /locus_tag="HVZ03_RS23140"
                     /old_locus_tag="HVZ03_23130"
     CDS             complement(24936..25583)
                     /locus_tag="HVZ03_RS23140"
                     /old_locus_tag="HVZ03_23130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_049074298.1"
                     /translation="MLSTSTFLALAMQCAASVHPDTTHEVARVESGFNPYAIAEIIPKV
                     KRKPGDKGVVSYFPESKEAALSIVKNIESRNHRYSVGLMQITSTNFAKFGTTAEKMFDP
                     CENLKVSEKILVDCYKRGGDLVRGLSCYYSGNPETGVKPEPEFNNTSYVQRIGFSPPDN
                     KKSFIVPSVKEMIKKENKTTITPEEIIIYPQYAMRGTVSNEKETKDVEIKSE"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(25758..26276)
                     /locus_tag="HVZ03_RS23145"
                     /old_locus_tag="HVZ03_23135"
     CDS             complement(25758..26276)
                     /locus_tag="HVZ03_RS23145"
                     /old_locus_tag="HVZ03_23135"
                     /inference="COORDINATES: protein motif:HMM:NF014417.4"
                     /GO_process="GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]; GO:0140673 -
                     transcription elongation-coupled chromatin remodeling
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_001446885.1"
                     /translation="MKGQKQFYLLQCSPHFHQSVLLQLSRSGIAYYNPVIRTFYKRRDC
                     SAYRGQIMPMFPGYVFVLLDFEVVHPSCFTRMKNVYGLVSFGEYPAEVPLSVINEVKEQ
                     EKIFSMNLSLMNNSCLAKILLLADASKRGQVFADYVCNRKYDRLKNDSYKRKAETATQC
                     TLPSYRSSC"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            complement(26629..27795)
                     /gene="mobP1"
                     /locus_tag="HVZ03_RS23150"
                     /old_locus_tag="HVZ03_23140"
     CDS             complement(26629..27795)
                     /gene="mobP1"
                     /locus_tag="HVZ03_RS23150"
                     /old_locus_tag="HVZ03_23140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP1 family relaxase"
                     /protein_id="WP_016247741.1"
                     /translation="MGVYVDKEYRVKRKSSENGRKSAFAHKVKNGGKNYSRNVQERINR
                     KGASKEVVVKISGGAITRQGIRNSIDYMSRESELPVMSESGRVWTGDEILEAKEHMIDR
                     ANDPQHVMNDKGKENKKITQNIVFSPPVSAKVKPEDLLESVRKTMQKKYPNHRFVLGYH
                     CDKKEHPHVHVVFRIRDNDGKRADIRKKDLREIRTGFCEELKLKGYDVKATHKQQHGLN
                     QSVKDAHNTAPKRQKGVYEVVDIGYDHYQNDKTKSKQHFIKLKTLNKGVEKTYWGADFG
                     DLCSRESVKAGDLVRLKKLGQKEVKIPALDKNGVQHGWKTVHRNEWQLENLGVKGVDRT
                     PSASKELVLNSPDMLLKQQQRMAQFTQQKASTLQSEQKLKTGIKFWGL"
                     /name="mobP1"
     gene            complement(27798..28343)
                     /gene="ddp1"
                     /locus_tag="HVZ03_RS23155"
                     /old_locus_tag="HVZ03_23145"
     CDS             complement(27798..28343)
                     /gene="ddp1"
                     /locus_tag="HVZ03_RS23155"
                     /old_locus_tag="HVZ03_23145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="WP_000757693.1"
                     /translation="MKKVQFRIDENQHDDLLDCLKTLYPDEPALTVAKGMKLLANALLK
                     SKAVSKDINTFFDNNDFIKTTMYLTGKQRADIERAANRHGWTLSRECRYRIQTTLENEL
                     DFFDQELLMMNRCRNSIDKIGRNFHYIIVNDQTRVLDKDGFYQDAERLTTEIFNLKNQF
                     ENYIMLCKGRTVSNKVEM"
                     /name="ddp1"
     gene            complement(28669..28941)
                     /locus_tag="HVZ03_RS23165"
                     /old_locus_tag="HVZ03_23155"
     CDS             complement(28669..28941)
                     /locus_tag="HVZ03_RS23165"
                     /old_locus_tag="HVZ03_23155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000160399.1"
                     /translation="MTKHDFVSFVSGELRQGAVRFSLAFNSKGEIVLHWTNKAGIRVWR
                     ILSGNRGKKPSKANLERMSNFRRWLFDARQGMEGYTQQPEQSNLS"
                     /name="hypothetical protein"
     gene            complement(28954..29103)
                     /locus_tag="HVZ03_RS23170"
                     /old_locus_tag="HVZ03_23160"
     CDS             complement(28954..29103)
                     /locus_tag="HVZ03_RS23170"
                     /old_locus_tag="HVZ03_23160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000003880.1"
                     /translation="MSERILSAINDVEKGGRPVFPLMPFHVFPEYMALLRKALEKKTQK
                     RTDK"
                     /name="hypothetical protein"
     gene            complement(29173..29352)
                     /locus_tag="HVZ03_RS23175"
                     /old_locus_tag="HVZ03_23165"
     CDS             complement(29173..29352)
                     /locus_tag="HVZ03_RS23175"
                     /old_locus_tag="HVZ03_23165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000439078.1"
                     /translation="MEREFSAKASLNRNIKFWFEQCGLSKERVIHCIDNWYDLAYPPSE
                     QEKAKKEAIEKLIK"
                     /name="hypothetical protein"
     gene            complement(29395..29724)
                     /locus_tag="HVZ03_RS23180"
                     /old_locus_tag="HVZ03_23170"
     CDS             complement(29395..29724)
                     /locus_tag="HVZ03_RS23180"
                     /old_locus_tag="HVZ03_23170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_046623240.1"
                     /translation="MKVLTFKNDTVSIGDIFVSSWGYEQTNVTFYQVLSVHGKKTVTVR
                     EIRANSEYTDSMVGFKTPVLNDFTGECFKRQIKDFGDELAIKIEDFETAYKTLPEEKHR
                     FSSYY"
                     /name="hypothetical protein"
     gene            complement(29817..30032)
                     /locus_tag="HVZ03_RS23185"
                     /old_locus_tag="HVZ03_23175"
     CDS             complement(29817..30032)
                     /locus_tag="HVZ03_RS23185"
                     /old_locus_tag="HVZ03_23175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001180116.1"
                     /translation="MQNKPTPEEVKNARVAAGLTLKEAADIFGYQLNSWQMKESAGKAS
                     RSLSIGEYQYLLLLANMHPSYRLVKK"
                     /name="hypothetical protein"
     gene            complement(30022..30267)
                     /locus_tag="HVZ03_RS23190"
                     /old_locus_tag="HVZ03_23180"
     CDS             complement(30022..30267)
                     /locus_tag="HVZ03_RS23190"
                     /old_locus_tag="HVZ03_23180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000356546.1"
                     /translation="MDKDKIIKKNRGNYSYVIRTMDEDGDTVFHVLKYVKTIDKTKSRK
                     TVRKLIMDEKLNLASLMLLDNGVLCDCLTKGDENAE"
                     /name="hypothetical protein"
     gene            complement(30312..30635)
                     /locus_tag="HVZ03_RS23195"
                     /old_locus_tag="HVZ03_23185"
     CDS             complement(30312..30635)
                     /locus_tag="HVZ03_RS23195"
                     /old_locus_tag="HVZ03_23185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001181903.1"
                     /translation="MQNYAKSVATEILRQLGGNRFIVMTGAKSFSYFDENGECGLTFRL
                     PSNFAMKGINLVKIKLDFTDTYQVKFSRVRGAEVKDISRFDNIYCDQLARLFTQETGLH
                     TVL"
                     /name="hypothetical protein"
     gene            complement(30781..31062)
                     /locus_tag="HVZ03_RS23200"
                     /old_locus_tag="HVZ03_23190"
     CDS             complement(30781..31062)
                     /locus_tag="HVZ03_RS23200"
                     /old_locus_tag="HVZ03_23190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000220560.1"
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLH
                     GHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADLR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(31052..31303)
                     /locus_tag="HVZ03_RS23205"
                     /old_locus_tag="HVZ03_23195"
     CDS             complement(31052..31303)
                     /locus_tag="HVZ03_RS23205"
                     /old_locus_tag="HVZ03_23195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="WP_000121743.1"
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL"
                     /name="plasmid stabilization protein"
     Typing          31671..32260
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="99.831"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          881..1326
                     /name="IncX1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.658"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(26633..27795)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.742"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(13832..15627)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.833"
                     /coverage="98.0"
                     /evalue="0.0"
     Typing          complement(17869..18794)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.353"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(18803..19512)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.734"
                     /coverage="100.0"
                     /evalue="8.06e-136"
     Typing          complement(19762..20819)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.717"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(21894..24043)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.861"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaggcttc aggtgaaaac tgtaacaggg ttaacgaaag tcaggcatag aaatgaggtt
       61 ggcgttactc tggcatctct ttctctttct gcgaaacggg ttttatttct cgcactttgt
      121 cagattgata caaaggaaat gttgaatgat gatattttgg aggttgatgc tgattttttt
      181 tctaagacaa ctactttgga taaatatgcc gcatatgcgg ccttaaaaga aggtgcaaaa
      241 gttctggctt caacgacatt agttttaaat agagatgatt taaaaaccct atctaatgaa
      301 ttgggaatat caacatctaa aaacaagata cctgacagat tggatttaaa tttaaccgaa
      361 ttttgtgcct attatgatca tttggctact gttcgtatta aatttactaa tactgcaaaa
      421 agatactttt caaaacttat tggctctgaa aacagatata caacacaggt gttaaaatct
      481 gttgttatct tgaacagtgt aaactccaca aacttatatc aggttatcag aaaatactat
      541 agtttaaacc ctgcgagtaa atccttcgaa atttcagttg accaactgaa agaggaaatg
      601 gggctttata atattgaaaa tggtgagaag gtatacagat atccaaagta ctcttttttt
      661 attcgtgatg ttataaacaa aagtataaga gaaatcatag aaaagacaga gataagggat
      721 ataaaatttt cagtggcagg aaaaaaagga cgtatggtgc atatgctaag atttgatttt
      781 tctctcaatg aagatatttc tctttctgat gatgaagcta aattcttgga agagtttgat
      841 aaaaaagtcc tctagtgaat atatgatatg aggtaactca tggctaaaat ctatcaattc
      901 cctcaggggg aagaacgtgc taaattcagg aaagaaatag ccaaggagcg taagaaacgt
      961 tttgcagtga aaacagggag cacttttgtt aagtggcttg gctggggatg gttttatctt
     1021 cgtcttcttg tcgcgagtgt tttacatttt atctttgttt ttgtgttagc cattcttggt
     1081 gcgtttaaat gggctgtatt ctggctgggt ggtattttgt gtgtcatcac ctggtatcat
     1141 ctcgatcacc agttatggac gccacaaaat ctgactatac cggtgattac ggcaacctgg
     1201 attttgggac tgctggctga gcctctgatg gagctgctca acaaaactat gccctggcac
     1261 aagttacttg ttcccgaacc tgcggacgaa agcaccgaga acagtagcga gataagccag
     1321 caatgatgct actcagcggt tatgccattc cctgcctttt cactgcgatg caggataggg
     1381 caaacgccgc aaaatgacgt ctctgacgcc attccgcaac gtttgcccgg tgacctacag
     1441 tcggttcttg ttggagaatt ttatgaaata tcaggtgaga gagtttatta acgaaaaata
     1501 tgctaaggct gttaatcttt taaaagataa tcttaaagaa aactaccatg ttttttatgg
     1561 agtacgatta agtgagattc tttttcctgc cagtgagtat ggcactgatg cattctttaa
     1621 agagtttgaa tcaattaaca gtgtaatact tccattagta atctttgatt taatacaacg
     1681 caagccaatg atgattatca gcttcgataa gatacttgat gccagtttgt tggaaggaac
     1741 aaatattgtg gttcttgaat gtactaccct cgctgatctt ctgacaaatg ataacattga
     1801 ttctttatat aaaagctaag aatctccttt cagtttatat tttctgcttg ggtcgccaag
     1861 tgttatcgag tctacttcat gtgagtaatg aagtgtatga taatgtgctg gatttttcag
     1921 ataatcaggg agtgatatta tttttccgta gctaattgca gaataaaacc agttgcggaa
     1981 tgtctcgctg tttgttttta aagcatcttt gggaataaat gctaatttta tgttagaaac
     2041 gtaattaaca ggtttaagtg tggtatgtct gttttgtcca aagtctttta aagcatctgt
     2101 aaattcatat tctgatgtat aattttctgt cttattacta gggtgtttta tctggaatat
     2161 gaatgaatag tagttctggc caagtatttc aacggtgttt gaatttatgc tcagttgttc
     2221 aataaccgct tctcttttat actctaattt gtctctgaca gattgatata caaccattgc
     2281 tgcatgatgt gaaccaccac tgtttaaagc tacatatcgg tcaagccaag agtaatattt
     2341 aacattaata ggatcgcgag ggttgaaacc ttcatgctca atgtgccata tattatcctc
     2401 ccagtctgaa atgttttcag ctttcaggtt ttgggcggga tacatccctt ccccccatga
     2461 ataaaggttt ttgaaccaac taccatttat tactttgttc catccacaac cgaaactttt
     2521 cgaggcagtc agagactgta tcttgttaaa atcgaaatcc agagagtggt ttttatctgt
     2581 agttattatg ttactcagaa tttcagccag atccctgtca atatatctta gtgagtattc
     2641 gctaaatata ttttcaagct gcaatatggt atctgcatcc gctgtaggtt caactaactt
     2701 aatatcagca agatttttaa acgttgcagc ggtcagctta tggtgatctg tcaacctgta
     2761 gagtttacag attaattcgg ttaaatatct catagatttt catccatact tctatggtta
     2821 gaattttgcc gattccagta accagtgatt ctttatgttt tcatcctggc tgttgtacat
     2881 cgccagcgcc gctttgagaa cggttgtttt gctctgccct gttctgatag cttcagcttc
     2941 cagtatgtcc tcaaaatggg ctgaaagtct gaagttcatc aactttggtt tacccactac
     3001 aggcgctctg gtagcgccgg agataaaacg cgcggtttct gcgtttgttg ctggttgctt
     3061 agattcatcg atgttcggac ggtttagttt taaagccatg aaaattgcct cttgtacggt
     3121 atgcattcat tgtaaatatc atagtatctt tatgatgtat ttacaatgta aagatcttgg
     3181 ttaatcttgt tgatattcct ataaaatccc aatttcctgt gccacaagtt caatctgtgc
     3241 tttcgctgtt gaaaggcttg atgcccggct aacgtcatgt acccctgccc cttcattaca
     3301 ggcgctttca tacacatcca gctcggatat ccgggttttc agaggttgaa tccagatgtt
     3361 gtccgaacgc agtaatttat ccagatcaat ggccgctttt ctgtggcggg gttttgctga
     3421 gttgattctg gtgaacagca cccacggttc cagggctgcg ttagctttct gagcggtgcg
     3481 gattttctct gtaacactgg tcagagtttc gctttcgaaa tcagaggacg gcttaaccag
     3541 tgttaccacg atatctgata ctgtcagggc gctacggaac tcctggctgt cgtggccggg
     3601 gcaatcgaca atgaggactt cacacagctt actaagtcgc ttaatttcat tgctgacgtt
     3661 tccgtaagct gcgtgaaccg ggatagtgag taagccgtta tctgtccgct tttcgttcca
     3721 gctcaacaga tcgtggtttt tatctgtctt gaggataatt accgacttac ctttattgac
     3781 cagcattgag cctgtgttag ccacgtaggt gcttttgcct acaccaccct tatctgatac
     3841 gacaagcaag attttaccca tttcagaatt cctctcttta tgacgtaaag gttatgtaaa
     3901 gactatctta tctttacatt gtgtgttgtt cgtaaagatt attttgtctt tacagtgtct
     3961 ttatattaca catgatttac catgtaaagc acaaataaag ataaacttgt atttatgttg
     4021 tctttattgt gtaaagattt atgtgtcttt gcagtggctt tacatggtaa agctgaggct
     4081 gtctttacat catctttatg ttgtaaattt ctgtgtgaca ttgtcacttt atggtcggag
     4141 gtctgttttc tggttctttt tgagtgtgcc tttcctgtcg atccactttc tggttcattt
     4201 tgggtatagt ggtgtgacct tatgcgaact ggttctgtaa tatgacttca aatgcaccaa
     4261 caaactttgt ccgcgcttat ctgagagctt caacagcaga acaggatgct tcgcgtgccc
     4321 tggaaactat cgaggctttt gccagggaaa gaggcctgat catttgcagc tattatattg
     4381 agaatgaatc cggctcccgt cttgaccgcc cggaactctt ccgtcttctg agagattgcc
     4441 agcaaaatga cattttgctt atcgaggatg tggacagact ttcccgactg tcaggggaag
     4501 actggaatac gctgaagaaa atgatccgtc agaaagatat ccgggttatg gccgtgaatg
     4561 tgccgacgac ctggattaat tctggtatga gtgagtttga cagccggttg tttgcagcca
     4621 ttaacgatat gctgctggat atgctggccg ctgttgctag aagggactat gaacaacggc
     4681 gggaacgcca gaaacaaggg atagagaaag caaggaaaga cggcaaatat aaagggcgta
     4741 aacctaatca agccagacat gatgcaatta tcaggttgat agaaagtggc agctcctgga
     4801 cacaggtaca gaaggtacta gggtgcagcc gcggcacaat cagtagcgca ataaaacgta
     4861 aatccctgca atcctccggt gagtagggta gggtgagctc aataaactgg ttgacgttat
     4921 ttatgaggga ggtgctgaag tggatatttt taaaaagcaa attgaatgtt gtaactaatg
     4981 agtatcaaaa taaaaggccg cttacgcgac ctcagccttt tgcggttttg gcttggtgat
     5041 ataccacgat agacaaccga caataaaact catgaacatt ccagtaaaac gatcatcgat
     5101 gcctggaaac aggcaaccga caaacatcgc aacagggaaa ggaagaagta aacagcgccc
     5161 caaaatgctc ataaaatcca taacacctcc tttgttaaag ggcaggaagc ggtgcacttc
     5221 ctgcccttag ttacgtttcc gcagtcatca atcgatgaac tgacggatca gttccagaac
     5281 tgcaatcagc gcgtttgcaa gcgcagctac cgccctcaga acgatgatta acaggttaat
     5341 catccgtttt ctccataaat ggagtaaaga caccgtggct tgctcttacg ctgcctgtca
     5401 ccacggcttc tcttcgtctt gtcagttgta gagagtctca ctcctaccag agcacagata
     5461 accagcacca cctgtattac ctgtcaggac tttgaagctg ttcatgccgc atttagcgga
     5521 atgcagggaa agactcacca cagcactaac cctctgatta tacgtttatc taactttcaa
     5581 gcaaaccgtt aacgcgtagt caccgcctgt catattgcat aatcaggctt cacggattat
     5641 catactgttg tcagttgtag agagtttctc ttccgggcga gttaccagct cgtaccggaa
     5701 ctgtaaaaaa gccgacctca ccagtcggtt tttttacgtc tgcagtttcc cgcttcattt
     5761 agatctattt taaatgaata aattttctgc ggcaaaccca acgacgttgg gtcgttagtg
     5821 taaataattg ttcaaaactc ataaacactc ctttgttaaa gggcaggaag cggtaaacgt
     5881 ctctccctta gttaagccat caatcactcg attagtttct gaatggcaat cagcgcgttt
     5941 gcaatggcga gcacagccct gagaacgatg attaacagat tcatcatccg tttctctagg
     6001 ttgatactgg aggaagtcac cgttgcttgc tcatacatcg cctgtcacaa cggctctctc
     6061 acattgttgg atgtagagta ccttccccct gccagagcac tgaacacagc accacctgtt
     6121 tgttcagcca ggactttaat tcgttcatcc ccagatagcg caggggttag aagcaaggga
     6181 ggcacactgt acagcgccaa cacaaagatt atacagatgc acgcataaaa ttcatttaaa
     6241 gaaatggcca ttgacagaca atctgaagtc aaactagaca actggtgtct agtgccataa
     6301 tattgtggat gttggatgta gagtatcttc ctccagtcag agccaccaac tcaggactgg
     6361 aaaacacgaa aaagcccgat taccagtcgg gtttttttgt gcctgtcgtt cgactgttct
     6421 tccgtttttt cccttcattt gggggatttt ctttcagttt ttttgttaag tccaatgctg
     6481 ccggtcgcgt tggccaacag atcaatgccg ttatcggcgt ttccattaat ccttttttca
     6541 gtaagttgca gcacaaaaga tgattaaaaa gctatcagtt tttttgatgg atacagtagc
     6601 ggcggtacgc tgcgtgaaat ctgataaaaa agcaggggga aaggagaaga tttttcacgt
     6661 agtctccgat aaagtgacta ttgatattta gcaatgaaca taaggagggt attgtgggag
     6721 ctacaaaaga ttgggttatg caagtcgagg aaagtcgccg tgaggaatgg atacgagaac
     6781 ggctttccag cccagatctt gaggaggatt ctgaagaatg gcagttactt gaaaaggact
     6841 atgacgagta tcaggacttt ctttctgata tggctatgga agaatatgaa aacgaaaaat
     6901 ggttaaaaca gcatccacat acagaaattt ataaaatagc aataaacctt ttagaacaaa
     6961 taaaagaaga gggaaaacaa tctacaagtg aagttttcat aaaaatgaaa atcgcataca
     7021 ttgtgacaat aatggaaaac tgtcttagcg aaatgattaa aagcgttgta ttgtcacata
     7081 acagatatgt agaaaatgcc ataagaaaca taaatgaact gaaagcaaag aatatctctc
     7141 tgtctgagtt gataaataaa gagtctaatg caaacaaata tgtacaggag tacctttcag
     7201 atattcttta tcatagaatc caactggtag ttgaaatata taaagcagtc ctgcaaccta
     7261 agcaatatcc acgttttcca ctcaaaaata tcaatgaatt gatgaaactg aggcatgaca
     7321 tagttcatcg taacgggaaa acgaaaacaa cggatgaaaa gatacataca ttcaatacag
     7381 ctacgctcaa tgatgcgttt aaagttgtag aggagtttct taataacatg atgaatttga
     7441 tcagtgatgc tgttgagcat catgaaaatg agcagatagc cagagatctt gaagacgagt
     7501 tttgagtagt atttttacta ttctgaagga ttctcaggaa caaatggagc agtacatggc
     7561 aacaaaaaaa tacgaactaa caaaagaata cttttttcat ggtgaatttt ggcaccaact
     7621 tgatgataac aaaggaagat tttctgcacg aattgaatat tcaccgtacc atggtctgat
     7681 tctagattat tgtatttctg acagtgaaag ccccagaaca tgtgaaatat tatatggagt
     7741 cttaaatact ggagaaagat gtactctaat tgggaaattt gatttcacac aagggaatat
     7801 tcattttgat aaagggatta tccatactgg aaggcatgga tttcccataa tgctattcaa
     7861 tgatttttat gcccccgact caaagataga atattgtgat ttatccttgc acggattgca
     7921 agaatttatc caccctcacg gttttttcac tcaattgaaa catttagaac atccaatatt
     7981 tatcgcaaaa ggaaaccatt ggactcttca acttgtcaac catgtatctt ttagcgtaat
     8041 tggtgatgat ctattaaaca taataaattg ccaaaacaaa gccgcactgg agaacataat
     8101 tcatcaacta aaaaagacaa aagagttata ccctgatgct tttttctcca ttagaaaaga
     8161 acttgttttc tactttagga taaaatcatc taatgattta ggaataaaag accatatatc
     8221 aaagtgctgg gatatttccg ggttattttc aattcttctg aacaaaccga ctcttcctga
     8281 agaaataaac ataaagttca agggaaatgg ttcgaagaca ccatgtctct taacaacggg
     8341 gtttgaacaa agaactattg acctagcgct gagggaaata aaacatcaac tccttccaat
     8401 aaacaggaag catattaatc ttggaaagat attctgcaaa tggttcaaaa tagcagaaag
     8461 atatatgcca ttgacaataa catatcagta tgaaaccggt tttcgaacac tgcatcaagc
     8521 tcatactgat attatattat ttgcgactca attagaagca ataaacaaaa caataggtgg
     8581 ctcaaaaaat gaaaaataca tgaaacccat taatgaatat gcaagtttgt ttcttattca
     8641 agagatagag atgtttttta agaaattcaa caataaatct attggtgaaa atattgccac
     8701 actcagaaat gaattagcac atgttgaccg caaaaaggag ttaatgaaca tattgacgat
     8761 tggtgattat gttaaaattg gaaactacct aaaaacaatt gtaacatctt atctgctatc
     8821 agatttagga atcaataaca ttattattga aaaatatcag gctcagacaa ttcaagagta
     8881 ataaaacatt atacaattac aattgtcatt taaatataat aagacgagaa acgagcaacg
     8941 gaaaagtaaa atcaatatca atttacctca atttgagcat tgaagccatt atcaactcca
     9001 gtgcaactaa acatgctaat aaagcctcta gaacagaggc tttatatgaa tatagtttag
     9061 cgtctcttcg cccactcttt ttcatcatcg gtgagttgtt ctttatgcaa ataatcacca
     9121 gggacagggg gaggagtaac cagtttagga cgcccattat catcacgaac cgtcaccaga
     9181 ccaactacct caccattttc tttaagcgcc catgcagcca gttggtatac tgttgacttt
     9241 cctgccacac cggagacatt atcgtgacgg aaataccagt ctgtcgcagg gataatttgt
     9301 ttgtaggatg tattactcat ggattttctt ccttaacaaa atgatgatat aaaactatat
     9361 ccttgccata ttactgctca tctgttactc cgttcaaact cttattgata cgaaaatctt
     9421 ccagagaacg cccggctttc aacgcttcat caatcggttt tggcgcacgt ccacgaccag
     9481 accagtattt cgtttcacca ttttcttcaa attgatactt gggtggcgct tttggtaacg
     9541 tttttttacg tgattttggt gcttcttcgg acagaccaag cagttcttcc ggtgagaaac
     9601 cctctccggc gattaactga agcagttcct gacgtttccg ttcacgctct gctcgttcag
     9661 ccgcttcacg ttcagcatct tcacgacgtt cttcaataac aacgttgagc ttttcctgca
     9721 tttcgagcaa ctgctcaaaa tcaatctcac gggcaaacac acgcaatgaa cgaatattca
     9781 tcatagtccg gctgataatg ccgtattcat cttctttagt cagttcgctc ataattaatc
     9841 ctcttgttta atggacgtac ttccatacgc cggaaggaac cttatcataa agtttattca
     9901 tcaccagttc tgcacggcgg tgatctgcgg cagaataaaa tgcctctgat tctgataaag
     9961 gcagcttgta acggttaatc tcaataactt tttcaagagt atctcttgat gtacattttc
    10021 ttaactgaaa aagccattcc tgctttgttt tcacttctta gcccttgccg gaaaacccag
    10081 cttccctgtt ttcttatcct caaggacaag aactgtatca tacgttccac cacttttctt
    10141 tttaaatccc ttaatcaaat cggttttccc tgatttaacc agtttttcgg cctgtgcctg
    10201 ggtgattttc ttaccagaaa actcactcca gattttaaat tcacatccgg tacagaaata
    10261 acctttcggc ctgataacaa tatgtttacc acaggaaggg cagggagagt ccaggtgttg
    10321 aaactgccct gctggcgcag cgggttcaat cttcatcttg cccaggtcaa catcagaaat
    10381 catgcctgtc aattcaccgt acagctcatt aataaactgt tcaaccgtca ggtcgccatt
    10441 ttcaatggca gtctgctttt cagaccataa tgctgtcata ttaggattaa ccgctatacc
    10501 tggcagggca tcaataagcg catatccggt atcagtcgga ataagtttcc ctttttccag
    10561 cgtgatatag tttctcttct tcagcgtttc cagaatggct gcacgggtag ctggcgtacc
    10621 aataccgcca tgttcatctt ttttgtcttt atccttatct ttcagtaatt ttttaatcgt
    10681 tggatcagtg acaaaatccg cgacacgaac aagcgcagca agcaaggagg cttcggtgaa
    10741 taacggcagc ggtgttgttt tcttctcatt aacaacaact tcttttgtcg tcagtgtttc
    10801 tcctgtgcga attttacaga gcagttcaaa agcggaatca tcattatctt ctgattcacc
    10861 ttcgtctgtg atttccgcgc caagaaacgc ctcaaatccg ctgtcagttg tttttctggc
    10921 acgggcatag aacgactcat caccacactg aatggcaacc gatacttcct ggtatgcttt
    10981 ttcaggcatg aactgaacaa gatagtgttg tgcgatcgcc aggtaaacat tgcgctcgtc
    11041 ggtgctgagt gcgttaacat caggcacact ggaggtcggg attatcgcag tatgcgcagt
    11101 cacctttgca ctgttaaacg ctttgctttt acgtgaagaa tcaatatcca gcgactgagg
    11161 aaagactgat ttcagggcat cgataacctg cggcgcttca ctgaattgtt catcagaaag
    11221 atatgagcaa tctgagcggt tataagtaat tgctttatat ttttcacgta gttgttgcgt
    11281 aatatccagc gttttttgtg ccgtcatttt aaacttcttg ttcatgtatt gctggagtct
    11341 gaccaggtta aacggcaacg gcgcagccgt ttttttatca tcagttgctg ctgcttcaac
    11401 tgtagccggt tttcctgcaa gggatgctgc cgttccgtct gcccacgcct tatcaagtaa
    11461 tttacggtcg gtcagcggag caaattcacc tggtttccag ttcgccctga gaacatcagc
    11521 accacgctga aaaactccgg tcatggtgta gtaaaaactg gatttatggt tctggttagc
    11581 acgggtacga ttcacaatca ggccaagaac gggtgtctgg acgcgcccga cagacagaac
    11641 gccctgatat cctctggctt ttgcaggaat ggtgtaagca cgcgtcatgg agaatccata
    11701 gacggcatcg gcaactgaac gcgccagcgc cttaaggtaa agccctttga aatcacgatt
    11761 atctttaaga tttgccagtg cctttttcac tgccggaagc gtgttgtcgt ttatcagaac
    11821 gcgctttacg ggttttgtgt ttcctgcata ttccaggact tcatcaacaa gtagctgtcc
    11881 ctcatcatca ggatcgccag cgtgaacaat ttcagtcacg tctccacgtc tgataagttc
    11941 gagaatcgtt ttaacctgtt ttgctgcact ttcaacaggc tgatacttca cgggataaag
    12001 acgtaaagga agcgtttcaa ccttccaggc tttgtattca ggattatagt tttccggcgg
    12061 ttgtgattcg ataatatgac caaaacagtt agtcacaatg gcgttatcac tttcaaacca
    12121 gccatcatgg cgggtaaaat tgccaccaag tgccttaaca atatcatttg ctactgcggg
    12181 tttttcagcg ataaaaagtc tcattttgtt atcctttaca ttgaattaat cttttggcac
    12241 aacggatagc gcgttcttct gacactgcct gttgccagtt atcttcactt acaggttgtc
    12301 tgaatctgtg ctcacagcca ttaaaggcaa aaattccctc acggttaagt atattcgttg
    12361 cgatatcctg gtctttaatt ctcaaaaagg ctgttacggc aaaaccagaa tacgaagcaa
    12421 tttttgaaat gatgcattca tcagctttta ttaacgctgc aaaaggaact atcttctgat
    12481 gaccacacga aattaaaggg agggtgtgaa tatcataata agctattgaa tgacaatcca
    12541 tacgggtatc atcaatagct gccagccaga atcctgtctg gtcttttatt tttctgctaa
    12601 tatctaaatc tgaaacatca gggtttaata aatatccacc ataacagaca tggaaggggt
    12661 gaacagattc atcaatatca ggaagttctt ttaccggatt ttctttccag tccttcagaa
    12721 caccaaattc aagagcatcc agcaaaaact ttcgttccat cccatcaaat aatgcatatt
    12781 gcatgtgtta atcctccagg taacttaaat agtcaggttg cgccccgttc ttcttataaa
    12841 gttcttccct ttcatctgct tcctgcacgc tcagatcaag ggttcctttc aaaaaggtac
    12901 gagcattttt tattacatcc acttatgcac taccagcaga taagcacaat aaaatagata
    12961 taatagattt ggttactttc atttctaacc tcagtgattg taactaatca tcacatttcg
    13021 ttggcgcggt atgtgatact tgcagtcccc tgatacccgt tggcgcgggt atcaggtttt
    13081 aatcaacctc tgacgcgacc aaacttactc atgatcagtg agattgcagc cgggtctgcc
    13141 gttgaacact gatttaaaaa attcttacgg agatcaaatg ttttacccca gcggattttc
    13201 ccctttttct tttcaacatt tttaaaaaaa tccttttctg cactgctgca ctcactccct
    13261 ccactactac cgacagcttt accataaaga caaaaaacgg atttacaggg atcagcggca
    13321 tacgttggcg ctataaaaca ggacacagta aaaattacga ttagaccttt gcatatcctt
    13381 ttcatagtaa cctctgaata tttattcttg acagataaat ttcaacatag tcattattca
    13441 accatctttt tagtggctga tattcaataa cacctgttgc accatttttt cttagccagt
    13501 ctttcgctga ccagtaacta tcaaaagaag atgtccttac aactattttt tcagaatggg
    13561 caacggcata aaaaacagaa tcatcgtaaa gatggttttc tggtttaaaa tcaggcaaca
    13621 ccttactcca tgaggaattt atattatttg atttaataac accggatgtt ggtttccagt
    13681 tcattatttg tgtattcata acttcaggcc ttttttccca ttcaacctgt ggcggttcag
    13741 gtggagagga acaggctgtg aggacaagaa tactgatcat aagtattttt ttcatagcaa
    13801 aacctcagac tccagctctc ctacggagag cattttttct tttgacggat atttaagccc
    13861 tttcacacca aatatttttt tcgtcttatt tagtttcatc gtcaatgatg ccagtttagg
    13921 actgaccttc attaacctgt ccataaaata cggatcaagg taataaagtg ccttttctgc
    13981 tttaacaggg ttctccccct tcaggatgat aaactcttct ttaaagtcca gcgttcccag
    14041 ttcctgtgga agcaccagtg ctcttcgggc ttcactttct gattcgccct gtgaagttga
    14101 tcgtccccgg ttcttgcttg tgctctttga tgtagtggta atatacccaa gtttttctga
    14161 tatcttcgcg gcatcatcct cttcgctgac agcatagata atacggcagg gatgagcact
    14221 catcagcgtt ttggctccct caataccata gatttcattt agctgactga tattctgata
    14281 aattgtcagc agtttaagtt tgaaacctgc aatataccct gatccctttt taataattgg
    14341 catataacca atcgaaggga actcatcaag aaacatcagg cagtcatgtt tcagggtggg
    14401 atcaaaatca ggattttcac gcaatgtcac ttcaacaacg aagttgaaaa acaggttcag
    14461 aaaatcgtaa gccagtgata tatcttccgc attaacaccg acataaacag tgatatcttc
    14521 ccgtcgcaac tgacggagat cgaaatcatt accatcagta catttacgaa cggttgggag
    14581 ataaaacagg ctcattttct tacggaaaga accatcaatg cttgaacgct gttcatcttc
    14641 cgtttcgtga tattccctga ttttggtcag ggcatcgcgc aaatgataca acgcgttttc
    14701 atcaagcccg tttgttccct ccagttcttc ccgcttactg agtatcagtt cccggtcaat
    14761 attgctgtac aagtcgacga cagaaccgat tgagaaaacg ggtttaagcc cgaactcatt
    14821 aagccaggac ggctcatagt taataaagaa atgaagcaac ttagccagtc ctgtccagta
    14881 ttgacccgca agattattaa agtgcgcttc tgcccctgtc atgccataag acggaaacag
    14941 aatttcaatc agtttaagca gatccttagc cccactctcc gcttttaaat caatatagaa
    15001 aaggggatta aactggtgtg ttttactgtt gaaagggtcg agcagataaa ctttattacc
    15061 cagcagtatt tcacgcacct tactggtgat tttccacaat tcctgttttg gatctaacgc
    15121 aatcagagag tgttttctga ccagaagatt agggatacca atggcggcac ctttacctgc
    15181 gcgggttcct gcgccaagtg atacaaaatc tggtgcggta taccacaggt atttaccttt
    15241 atatgctccg acgagaatat cagtatcgtt ttctttctcc catttcagaa gtttcgattt
    15301 ccttaaatca ttatcactgg caaacttcgc gtcaccataa agagcaacag ccgttttatt
    15361 cagttgccag ataataaaaa caggcacgat gagagacgaa accatacctg ataaaagaga
    15421 ggggatagcg gttaacctga tatctgtccg tatattactc tctgttatta ttcgccacag
    15481 gagcatggaa tcaaaatttt tccatatata aagcggcgtt tttccgttca ggaagtaaac
    15541 agcaacagaa ccagtataat atgtcacgag acacataacc agaccgataa aaacccactg
    15601 gcctttatcg gggagtttta aagacataat cactccttca gttttctgaa atagtcatca
    15661 aaatgaagtt gtttgtaata aataccggaa gcgaaacgaa aatcttcatc atcaaggtat
    15721 ttaatactca tgataatatc aatattactc agtacacgtc ttaaaatgac attgaatggt
    15781 agattctgac attcaggatt catataacat cgctgaacaa tcccaagcac agcatattca
    15841 ggactacttt cgtgaacggt ggtaatgttt cctgcatggc ctgaactcga tgctttcaga
    15901 aaatcccatg cctcagcccc cctgatttct gtcatcagaa tcctgtccgg attcatacga
    15961 aaacaggaac gcagaagact cgctgaggta ataaccttac tctcaccctc tgccggatag
    16021 taaagtttta catggttttt atggaatctg aattttgcct catcagtatc ttcaatagaa
    16081 atacaccgca gatgatgcgg tatatattcc agacaggcat ttgcaaaggt agttttacct
    16141 gaacccgtcc ctccacagaa aactatcgtt ttcccctgac gcagtgattc aggtataacc
    16201 cgatcaaaat atccggaagt gattaaagca gaaatattat cttccataac cgagtcacca
    16261 cttaaaccac tgacgcgtga ataaaatccc tgttttataa atttgtcatg actgataaaa
    16321 atacctgacg gcttacggat tgttatagaa acagtatctt tttcagttgc cggtgggatc
    16381 acaacctgaa cacgttctcc acccggaagc gtggcagagc gcaggggata ttcaggagtc
    16441 acagaaccgc cgtcatgaaa atcggccagt gtggatgcaa aagaaagaca atcactgtaa
    16501 ctcatctttt gttcatacca ttgccacttt cccctgacct ttataaatat ttctcctggt
    16561 cggttaacag caatttccgt gacaccctca atctcattca gccaatgata aaaataatcg
    16621 ttgaccacat cataaatcag atgtctgttt tcgttattca cattaacccc ctttcatttt
    16681 cagtttataa atgcctgaaa aatccagatc ctgaccgaca atcagagtaa taatttcgcc
    16741 ctgattttta taaagcgttg gcggaatatt cacactatta gaaaatgctt cgcgtgctat
    16801 atcagcaaaa gcctggcgac tgtttgccgt atagtcggtc tggctgtccc tgttgttctg
    16861 tgcaatacca ctggcggcct gacttaaatc cggtatcatc ccgaccatca ttgcaccaag
    16921 aaaacgttca ctgaaatgag tgtcaatcca cccagaagca ccggcttcgc ctaacgcgcc
    16981 agccgcctgt gagtcaacca ggggaatatc aataaaaggc ttactgcggg tacgtagctt
    17041 gtaagccata acaaacacac gcccttgtcc atgatttaaa gacccggcct tatacatcag
    17101 ttttgcggcg gttcctcttt cgataagttt tacattaccg ctggcgctgt atatatcgct
    17161 gttgaccgta cattccagtt tccccgccag gtcagaaaca aaacgcctgt ccagtgaaca
    17221 gggaattgat gtcccttccg ggataaacaa atttgggtca tatggaagtt tcgttatttt
    17281 cgccagtggc gcagattctg tagtctgtgc ggttgctttt gcttcatcct ttttatcgct
    17341 ttctggctca ctggccgcag tatgtgaaac tgacgttccc gctgaactgc tgctgtttcc
    17401 tgtctggctg ccatcaagag aaacgtcaag tgcacggctg aagctctgct gtttattttc
    17461 cggcggttca gtcttttcag aagaaatgac tttttcttcc tctggtttct ctgttttttt
    17521 ctgtgcggta ttaaaaggat cgatatcttc gctcagtccg gtctgacgtt tagccgctcc
    17581 ggttgcaagc ggctgacttg cgggtttctc atcccctgac gacacagaac ggataatgga
    17641 cgggatataa taaacagaaa caccggcagc aagcagaaga aaacccacga cgaggataat
    17701 catcccttta cgtgactttt taagtttttc aataccaagc tgcaatgctg gcttgccagg
    17761 ctcttcttcc ggagtcttcc cggcctgttc cagttctttc tgtctgcgtt cccgtagctg
    17821 ctgttcaatt tcggttgcag tcgggatttt attttcctgt tcagtcactg gatcacctct
    17881 ttcttaacat ccggggatac cgtatctccg gctggtaaac gtacttttcc gaagccctgg
    17941 ttctcaatcc ccaccacctg ctcaccaaga cgtaaaacaa aacgcttatc aaccggtacg
    18001 ccaacaaccg taaaactccc gctctgttta atcacaggat tggtaagagt ctcctgcata
    18061 ccgttcatca caaagacgct gggaattttc tttaactgac tgaagccgaa ccaggtataa
    18121 cgaccatcgt catatgcata atcagggctg atatcctggc tgccttcagc aacccgcttc
    18181 cagtactgcc agttacgggg cgatttcgca ttttccaggg aacggttgat tgcctgctcc
    18241 tcctggcgtc tggcaagagc ctctgtgcgt ttcttctcaa tttcggcctg ttccttccgg
    18301 cgttcctgcg gatactggta attcaccaca aacgcaattt tctccggctg ccggaacgtc
    18361 cgagcgttca gctccatgct gtaattacgc ttcgtggtgc gaacaaacaa attcgttcgc
    18421 cagcgttcaa gctcattttc cgggtcaaga gcaacactga cggattcaga agaggtatta
    18481 ccgttttcat ccatattatt tttctgaaca gtctgtttaa caggacgaac ttccaggtat
    18541 accaggttat cttctttatt aaccgcccat ccctgcggaa aaccagttct ggcactgata
    18601 actgtttcat cttcatcaaa taccagtgtg gtggtgtatc caacggcact gttaattatg
    18661 gtggtattat tggggttata actgactatc tgattgcgtg ggtcaaagcg actgcctgaa
    18721 ggaagaacag cagcatgaca gacgtgcgcc gccatcagaa gcgccataat taacgctcct
    18781 ttattcattt tcatattatt aacctctggc ttctttatcg cgaacgtagc ttgttacaac
    18841 gaacttaaga ggattgttat tacgttcccc cgacaccatt tcaacctgcg gttcgatacg
    18901 ataagtcagg cgaacattcc agaactcctg gcgagtttgt ccggtagcaa catccctgat
    18961 ggtcagacga aaacgaatat acgcaccgat atctttatca tctgcccgtg acgaaggtga
    19021 aattatgaca gatggattat cctgaaccat tgccgttttt tctgctttgt tataaacaag
    19081 ttttggtgcc tgttcactgt taaataatgc gttataatct gccgcgacat tctccgcgct
    19141 gtaagccatt acataatcat aatcatgctg gagactaaaa aaattataac cttcacgatg
    19201 ttttatatac tgggtaataa aatatcgggc aatggcttcg ttttcagaaa gatgttcttt
    19261 tttaacagaa gtcagacgtt cagccacgcc tgtaacctta tcgataaggt aggcatcaac
    19321 aactgttgtt ttcagtggta atgctgcatt taatgcaagt aaagacagcc caccaattaa
    19381 catgcctccg ataccaccga atttataaat acgattcatt ctctcctgta gtgcaatgtt
    19441 tttttcttca aacgaaactg atgagtcagt aacgtctttt ttatttttaa atccgggaag
    19501 tttaaattcc attttgcatt acctcagcag aattaacagg ttcgcttttc ccggaaacgg
    19561 gcggtagttt atgtgacgcc tgacaaccag cgagacaaag cgtcacgaaa gccacaataa
    19621 gtagtttcat aatatgaaca cctgtataac agattaatat ttacagaaga ctcagtgcga
    19681 acagaaaaga taatagagcg cgccaggccc gacaatgaca attatgaaaa gaacattaaa
    19741 aggcgctcat aattaaatta cccaccatac attttctttg ctctctcaat agctgcctga
    19801 cgaagctttt tggcaccaat attaacgccc tgtccggcta ggttagctgt cttacccgtt
    19861 attcccggag actgaccaaa cccgccttcc tgacgacgca gacctttcca tgcaccaata
    19921 ccggcatttc tgcccatacc aagtgcgcca cgcgccatac gggatgcacc gaaaacgcca
    19981 gcaccaatcc ccatagcggc tgcgccctgc atggcacctt caacacccac acctgcaatc
    20041 tgtgaagcat aacttttcgc ctgccagata atccaggcca tgaaaatgcc agcaacagcc
    20101 gcagtagcgc caatcttaat tagattacga ttgtctaccg tatctattgc cagagataaa
    20161 actatattga gaaatgatgt tccggctctt aaagctaatg aaccgaacat aaatatcaag
    20221 catgaactga aaataagctg caaccagcta ttaaacattt gtctcaaaaa accaaacatc
    20281 aggcaaaaga taaaaacagg tgcagtgaca gtcaataatt tcagggttac ttccgcagca
    20341 agaaaaacta tagcacatgc aactaatgct aatattccac caaaataagt aaaaagagca
    20401 gctatagctc catctgtttt tacataagtt gaagtatcct tagacataac atgcgcagca
    20461 acctgttgta ctttcgtcca taactgatct aaccataacc aagcatcatt attaccagat
    20521 aacgaatcct ttaaaccatc tattgctacc agggaagtat ttagccaccc acctgcattt
    20581 tgtacaaaca ttaagattat agaaaacctg cacaagttcc agataaaatc aggcacaggt
    20641 gtttgctgtt ttctagccag aacagtaaaa gcataccata acacatagat ggacaccccg
    20701 tagcgtccta gggtgcctgc tatattactt aaacttgtta actgaccaga aaccgaagca
    20761 tcgagaaccg agaggatctc ttcttttgct gtgacaaaaa aattacttgc ttcagccatc
    20821 tcttgtttcc ttatttttta ggcatatcac ctttttcttc atgattagaa gcatctttat
    20881 attttttaaa atactcttta aaatttggtt ctttggcatg aagttgttga taacggaaat
    20941 tagcttcttt tacatttcga caattctggt tgtcacttcc ggttttctta cactcagctt
    21001 cttttttcaa tgattcttca tggtgctcca accaccaatc aacagatttg gtttcctcac
    21061 atccgacaag ggaaaaaata ctgagtgcac caatcaaaac aaaagacttt ttcataagac
    21121 aacctctctt cagtttaaag tgtatcttct cgctgcatcc ttaaatgaag gttcttcagc
    21181 ctccagttgt tgttttctga aagcagcctg agccatcttc tctttatatt ctgcaagatc
    21241 tcgctgctta tcgcgataca tttgatactg aaatttgagc ttctcgaact tcagttgttc
    21301 aagtgcaaca gcgtttgttg catcctgcgt ggccttcgta tccttcgcat ttttgacttg
    21361 atcaataagg tctttcatcg tctggttgtc ctgacgaagc ttgctctcca gcttgttacc
    21421 gtattccacg cttgccagtt gagaaaggaa cgtcgcttca catccccgta ccaggtcacc
    21481 agaatatccc aggttatgac aggtatctgt taccttgtaa tccgacaata atgatttggc
    21541 ctgttccgat aacgctcctt caggattctt aatgtaatcg tcaataaaag cattcccctg
    21601 atcataaatc tgcatcagct ccttactcac tgactgtgcg gactgcacca gtccctgcac
    21661 atcacggatc cccgtttttg acaacagctc ctgcttgtat gcgtttatct gactttcgta
    21721 atgtttcacc gtttccgccc attgcttaag gcgttctgtc catcgtccgg cttcaatcgc
    21781 ccattcaggg ttggcgtcaa tggcaacagg tatccctgcc tgagcgccgg aaataacaat
    21841 cagtgaagcg acgaatgccg ccataatttg ctttttcatt ggtgattcct caaatcaggt
    21901 tcgcctgttc cagataggta tcaagccact cttccggctt cattccttct ttccagattt
    21961 catcgaacag ttctaactgg ggttttgatg cactgagaac cggtaagtaa tacgctgctt
    22021 ttcccagctc cagtctggca aaagcagcaa aatcatcact ttcacctttc ctctgtgggt
    22081 tcttaacaac caggaactgg cgggacagcg gatcaatagc tttaattttg tcaaaataaa
    22141 gctccctgac ctgcaaacca tcaacatatt cactacgttt ggctttcggg tttgccagat
    22201 agatatgagt ggcgcattgt tcacgaaccg ctgccgcaat gggtgattta atcagttcat
    22261 ccggtgactg tgtggctacg acaagcacca tatcgagttt acgtccggtt ttcagcttgt
    22321 tgtaaacaaa gtccctgaac gcttcgttat tgatccattg ccagaactca tccatgtaga
    22381 taagaagcct gcgaccatcg gccagcatgg tgacccgata gatgagatag aatgaagcag
    22441 cactggccag caccttatta tccaggaact ccgttccatc aataccgaaa acatccaggt
    22501 tatcgacatc aaacgtgtct tcccgattgt cgaacaccca gccaaactct tccccctgcg
    22561 tccacggctt aagacgggct ttaagtccat gacgtttggt ttcagtatca tccggctcct
    22621 ggataagagg ccgtagttta ctgacaggat aagagcgatc tgaccgttgc ataagacgtt
    22681 caaccgcatc tgaaatcagg ctgttctggt aatcatcgag cggctcactg ttgagagtac
    22741 aaagcagcct caccaggtcc ttcataaaag cgatattacg ttttgttggc ggcagtgcgg
    22801 cgggattcca gcctgtcggc tctccctcct tcacccggta ataagatccc cccattgccc
    22861 gtataccgac ttcacctgcc cggtctttat cgaaaaaaac cgtggtcagt tttttcagtt
    22921 ttctgtttgc agggaatgat tccggcgtac cgaactgctg ggcggcaaat gcttttgtca
    22981 tcagtaatac ggttttaccc acgttagacg taccgagaat ttcggtatgc cccagcgtcg
    23041 ggttcttacc gaagaaattc tgatgttcag tcgtcatatg gtaattcaga tggtagatat
    23101 cattacctga cccccgaaga gtaatcagtt tttcccccca ggtatttcct ttttcttttc
    23161 ctgaaaagaa attatgaaaa ctttccattt cggcaaaatt aagactactg agggtactca
    23221 gacgagggcg aagcgtataa tttcctggta gctgagcaaa ataagctgcg ccaagactca
    23281 gtgttgaata agtgacaatc agccccaaat cttccagagt ggaagtcacg atattggtgt
    23341 ctttcaccag acgctccggt gaatccgcaa agacaaccag ggtctgatgc gatttcccga
    23401 aagaaatata tccactggaa accatatcca gtccgacttt cagatctgcc agcaaagatt
    23461 tggcagcatc atctgtcatt tccagcttat cgatctgatc atccagcgcc ttaatcgctg
    23521 actgcttatc catcgcagta aaggacgatg tcacgacata ctcaacgggg agatacatca
    23581 gagcatccag aataccggca tccgtctcct gaaaataatc cttaatctct atgcaacgaa
    23641 aataccgggc atggtctgac gcggtaattt gtccggcatc attaccaaag aacaggtctt
    23701 ttcctcccag atatgtataa aacggactac tgctaaccct gaccttttgc catcgaccag
    23761 aaagcagata ctggaacaga gataactgat ctgaataaac aaccccatga tcttcataaa
    23821 gcccaagacg tcgggaatga aaacgggaca gataggtatt caacctgtca caaatttcat
    23881 tcatttcatt aacaggctct ttaaagatat ctttttgttt tttactgcgt gaaaagaaat
    23941 gtgttacttt atcttccgta gtaaaaggtt taaaacaaat cgtcagaaat aatttattct
    24001 cgaaaaattc agactgaggg aatgactcgt aataatcatt cattactctg ttcacaaaag
    24061 gaattttact gttaaatact ggtctgacgc cctttttaca cctgatacga tgaggataaa
    24121 gcgtaacaga tttcccttca aagctacgta taagcgtatt aagctgatct gtcagaattg
    24181 acaaatcttc agaatcaaca cactcaaagt aagcaccgtc tatctgccag gttgccagca
    24241 aatcccggtt ttttgtaacg ataatattat cagtgatatg tgaagagtac ggaattaact
    24301 cttcaacaga agactggtct ttcagcttca taaagttatc cacttttgaa atatcaactt
    24361 cgttgtactg gctccccgcg taatggactg cgctgaatcg cttgtttgat aaaggatgcc
    24421 ctttgacaag agttctcaga tacagaaggt caaaaaagcg ttcatcaaac tgtgttacac
    24481 gcctgatggc ataccagcca ggaagaatga gggcatacat agcctcatga atccagacac
    24541 caagcagaac acaaataatg cacattccaa gaaaggggta gagcggaacg cccagccccc
    24601 ttattaaagc agggcgcgta agacctttaa aaagagtact catagtgcgc ccatccttta
    24661 attacgcaag ccagtcagga atatatggtg cgacaataaa gatgataatt ccgataacaa
    24721 gtgggactat ccatgaggta tgttgacgag aaaatatcgc aatataccca ataacaagag
    24781 caataattgt aattgcaggc ttacgaatat ccgttaaaaa atcgattatt ttctgtaaaa
    24841 aaccagttgt cttcgtagac acatcatccg caaaagcagg ttctgcaaca caaagcatca
    24901 acgcagccat aaatagagaa agcgttaaat aacgtttatt cagatttaat ttcaacatct
    24961 tttgtttcct tttcatttga tacagtgcca cgcatggcgt attgaggata tataatgatt
    25021 tcttcaggtg tgatagtcgt cttattctcc tttttaatca tttcctttac agaaggaaca
    25081 ataaaacttt ttttattatc aggagggcta aatcctatac gttgtacata acttgtatta
    25141 ttaaattcag gttctggttt tactcctgtt tctggattgc cggaataata gcaactcaac
    25201 ccgcgcacta agtcgccacc tcgtttataa cagtcaacca gtattttttc tgatacctta
    25261 agattttcgc atggatcaaa cattttctct gctgtcgtac cgaactttgc aaaattggta
    25321 ctcgttattt gcataagtcc tacagagtaa cgatggttcc gtgattcaat gtttttaacg
    25381 atactaagtg ctgcctcctt tgattcagga aagtaagata ctacgccttt atcaccaggt
    25441 ttgcgtttaa cctttggtat tatttccgca atcgcatatg gattaaaacc tgattcaacc
    25501 ctggcaactt cgtgcgttgt gtcgggatga acgctggcag cgcattgcat ggcaagcgca
    25561 agaaaagtag aagtagataa cataaatatt ccacattcag aacaccgggg cgctatccct
    25621 cgtcaggaat atcatcccca tgaataagtt ctttcatcgc ctgagatttg tattttttaa
    25681 taagatactg aacaaaacca gaatcagaga tacgtctccc cctcttgaaa cttatttcaa
    25741 ttgcaatttt ttcaacttca acacgaactt ctgtaggaag gtagagtaca ttgcgttgcg
    25801 gtttccgctt tccttttata gctgtcattt tttaacctgt cgtattttct gttacacaca
    25861 tagtcggcaa agacttgtcc acgctttgaa gcgtctgcaa ggagaagtat ttttgccaga
    25921 caggagttat tcatcaggct taaattcatc gaaaaaatct tctcctgctc ttttacttca
    25981 tttatgacac tcagaggaac ttcagcagga tattcaccaa aactgaccag tccataaaca
    26041 tttttcatcc gggtaaagca ggatggatgt acaacctcaa aatccagaag aacgaataca
    26101 taaccgggaa acattggcat gatttgtccc ctgtatgcac tacagtcacg cctcttatag
    26161 aaagtgcgta taactggatt gtagtaagcg ataccgctcc gggataactg caacagaacc
    26221 gactgatgaa aatgcggaga acactgaagc aggtaaaact gtttctgtcc tttcatactc
    26281 aatccccgat atacagatgt gacaaaacac aagccaaccg tggttgcttg tgagaaatca
    26341 cgcccctatg aagagagact ttttactatt gcgcgaagtt tatactacaa gtggcttatg
    26401 ctaagttcaa cacataaaac agatctttcg atcttgataa atcaatttta cttttattta
    26461 ttctacataa gcaacaaaac acagaatatt catcttttgc agatctgttt tttagatcga
    26521 tagatcgaat gatagctaaa acgcagaatt tcgatctgtt tttaaggtga aaagatgagc
    26581 aagcgaacta aaataaatat ttttctcgca taatcaatac attaaatctt ataagcccca
    26641 aaatttaatc cctgttttca gcttctgttc tgactgtaac gtggatgctt tctgctgcgt
    26701 aaactgcgcc attcgctgtt gttgcttcag cagcatatca gggctgttca gtaccagctc
    26761 tttgctggct gaaggtgttc tgtctacgcc cttaaccccc agattttcta actgccactc
    26821 atttctgtga accgttttcc agccatgctg aacaccattt ttatcgagcg ccgggatttt
    26881 tacttctttc tgaccaagtt tcttcagtct gacaagatca cctgctttaa cgctttcccg
    26941 cgaacataag tccccaaaat cagcccccca gtatgttttc tcaaccccct tgttaagagt
    27001 ctttagcttt ataaaatgtt gcttagactt tgttttatcg ttctgataat ggtcatagcc
    27061 aatatcaaca acctcataaa cacctttctg tctttttggt gctgtattat gtgcatcttt
    27121 aacagactga ttaagtccat gctgttgctt atgggtcgct ttaacgtcat aaccttttaa
    27181 cttcaattct tcacaaaaac ctgtacgaat ttcccgtaaa tcttttttcc tgatatcagc
    27241 gcgtttaccg tcattatctc ggatacgaaa aacaacatga acgtgaggat gttctttctt
    27301 atcacagtgg tatccaagaa caaaacggtg attaggatat tttttctgca tcgttttcct
    27361 gacagactcc agcaaatctt caggctttac tttcgctgaa actggaggcg agaagacaat
    27421 attctgtgtg atttttttat tttctttacc tttatcattc atcacatgct gaggatcatt
    27481 agcacgatct atcatatgct ctttagcttc cagaatttcg tcacccgtcc atacccgacc
    27541 gctttcactc atcactggta gctctgactc acggctcata taatcaatac tgttccgaat
    27601 cccctgacga gtaatagcac ctccagatat tttgacaaca acctccttac tggcaccctt
    27661 gcggttgata cgttcctgaa cattgcggct atagttcttt ccaccatttt tgactttgtg
    27721 agcgaaagct gacttacgac cattttctga tgactttcgt ttaacacgat attctttatc
    27781 aacgtaaacg cccataatca catctccact ttatttgaaa cagttctccc tttacataac
    27841 ataatgtaat tctcaaactg attcttaaga ttaaaaattt ctgttgtaag acgctccgca
    27901 tcctgataga aaccatcttt atcaagaacc ctggtctgat cattaacaat gatataatgg
    27961 aaattacgac cgatcttatc aattgaatta cggcaacgat tcatcatcag cagttcctgg
    28021 tcaaagaaat ccagttcatt ttcaagtgtc gtctgtatgc ggtaacgaca ttctcgtgat
    28081 aacgtccatc cgtgacgatt agcagctctt tcaatatcag ccctttgttt acctgttaag
    28141 tacatcgttg ttttgataaa atcattatta tcaaaaaacg tatttatatc cttactgaca
    28201 gctttacttt ttaataaagc atttgctaaa agtttcatgc ctttagctac tgttaaagct
    28261 ggttcatccg gataaagagt tttaaggcaa tccagcaaat catcatgctg attttcatca
    28321 attctgaatt gaactttttt cataaaattc tccaacaaga accgactgta ggtcaccggg
    28381 caaatgttgc ggaatggcgt cagagacgtc attttgcggc gtttgcccta tcctgcatcg
    28441 cagtgaatct ggcgccgctc ataaattgtg cttgagcatc aacaaaaatg caaaaaggct
    28501 gatgttgtca tggctgaaca tacgtacgtc tgcgaccgga aacccgatca atgcggtaag
    28561 gacagtgccg tcaggttcgc tccgcgaacg gtctggcagg aagcgcaagc gcagccccgc
    28621 gcaatatatc agaaagcacc tcccgaaata cgggagggct tcggctattc agctaaggtt
    28681 gctctgttca ggttgctgag tgtagccttc catgccctga cgggcatcaa aaagccagcg
    28741 ccggaagtta ctcattcttt caaggttagc tttgcttggt tttttgccac gattaccact
    28801 taatatccgc cagactcgta ttcctgcttt attagtccag tgcagaacaa tttctccttt
    28861 gctgttaaaa gcaagagaaa agcgtacagc gccttgccgc aattctccac tgacaaagga
    28921 cacaaaatca tgttttgtca taaagcctcc ggtttattta tctgttctct tttgtgtctt
    28981 tttttccagt gcttttctga gtaatgccat atactcagga aagacatgga atggcatcaa
    29041 agggaaaacc ggacgcccac ccttttcaac gtcatttatt gctgataata tgcgttccga
    29101 cattttattc ctcgcaatag aatcaggtgt cacggtatca ggttgcccca caacctgata
    29161 ccatctttat ctttacttta ttaacttctc aattgcttct ttttttgctt tctcctgttc
    29221 tgatggtggg tatgcaaggt cataccagtt atcaatacaa tgaataactc tttctttaga
    29281 taatccacat tgctcaaacc aaaattttat atttcggttt aatgatgctt ttgcgctaaa
    29341 ctctctttcc attttcagac ctttactaaa agggggaata tcccccctga ttaattagta
    29401 gtaagaagaa aatcgatgtt tttcttccgg tagagtttta tacgcagttt caaaatcttc
    29461 gattttgatt gccagctcat caccaaaatc ttttatctga cgcttaaaac attcaccagt
    29521 aaaatcattt aaaacgggag ttttaaagcc gaccattgaa tcggtatatt ctgaattggc
    29581 gcgaatctcg cgaacggtga cggttttttt accgtgaaca gaaagaacct ggtagaaggt
    29641 tacattggtt tgctcatagc cccatgatga tacaaagata tcaccaatag agacagtatc
    29701 atttttaaaa gttaatactt tcatttttag ctcccgccca gcttgggctc tggatgaaag
    29761 agaacctgtt tccctttcct gtgttttatt atacctgcat ttgcaggtat ggcaagttat
    29821 ttttttacca gcctgtaaga cggatgcata tttgctaata acaataaata ctgatattca
    29881 ccaatagata aagaacgact ggccttacct gcactttctt tcatctgcca ggaattcagt
    29941 tgataaccaa aaatatcagc agcttcttta agagtaagac ctgccgcaac ccgcgcattc
    30001 tttacttctt caggtgtagg tttattctgc attttcatcc ccttttgtca gacaatcaca
    30061 caaaacccca ttatccagaa gcatcaatga tgccaggttg agtttttcgt ccattatcaa
    30121 ttttcttact gttttcctgc ttttagtttt atcaatcgtc ttaacatatt ttaagacgtg
    30181 aaaaaccgta tccccatctt catccatcgt tctgattaca taggagtaat tacctctgtt
    30241 tttcttaatt atcttatctt tatccatatt attcctcata actaaaaaag gggcttaatg
    30301 ccccttttta tctataacac ggtatgtaac cctgtttcct gtgtaaataa acgcgctaac
    30361 tgatcacaat agatattatc gaatcttgaa atatctttaa cttcagcacc acgtacacga
    30421 gaaaatttca cttggtacgt atcagtaaaa tccagtttaa tttttactaa gttgatgcct
    30481 ttcattgcaa aatttgacgg taaacggaaa gttaacccac actcaccgtt ttcatcaaag
    30541 taagaaaaac ttttagcacc agtcataaca ataaaacgat taccaccaag ttgacgtaaa
    30601 atctctgtgg ctacagattt agcgtagttt tgcattttta acctcccgcc cactttgggc
    30661 tctggatgaa agagaacctg tttccctttc ttgtgtttta ttatacctgc atttgcaggt
    30721 attgcaaatt tttaatgctc tcgctctgac tgtaaacagt caatcatttg atgattaatc
    30781 ttagcgcaaa tctgcgatct gatagacttc gctgctttcc cttcttccaa cggcaataac
    30841 gagtaaaacg actttctcat caatgacttg atatacaagt ctgtagccag atgcacgaag
    30901 tttgatttta tagcgatcag catgaccatg taaccgggct gcgggtacgc gtggattttc
    30961 cagccgttct gccagtttct ttttgaattg ttcacggatg gtgtggccga gtttctgcca
    31021 ttccttcagt gctctacggt caaaagccag ttcataggtc atccaggtta accttcacaa
    31081 tttccgggtt tttcatgcgc tcatcagcaa cagcgtttaa ctcagcatct tcagcgagtt
    31141 cccgatagta ggcgtaaagt tttggtggaa cgcaatagaa cgccggttcg tttcggttca
    31201 ggatcgcaac agcgtcccct tcaccttcag ctacggttcc cataggattt tttttcaggt
    31261 cagtaatact ggccgctgtg gttgtcagaa tttgatagct cataaaccct ccgcttgtct
    31321 cattggcata atagcatctt taaaagcact cttaaaagtg cttatgttga gaaaaacatc
    31381 agaacaggtg agatatggct ctttccgaca tcgccttaaa acgctctgta acgcgttctg
    31441 agcgtttttt cccgtttcgt tgtagtcggc tacggtttaa cggtttttaa cgccgctcaa
    31501 cgctttttag cggccttgtt gctgtgatct gttgccatga tccggataga agttcaatct
    31561 tgatcaaaat ttcctcaagg caacgactgt tttgtaaata ccctctaaaa cgcgctgtat
    31621 cgcattctga gcgatttttt cgatttcgca tggtttcacc atggttgtat cgaacgaagc
    31681 ggcagaaagc gattcagggc ttctcagtga aagatccaaa aaggatcaat caacggatcg
    31741 tatgatctga actcttctgg ttttgagaaa ggagacaccg ctcgccgcag ccgaacgacc
    31801 gagcgtagcg agttagtgag cgaggaagcg gaacagcaca aggataacat caggcaatta
    31861 cgcgcagtgg ttaaaaagcg agcatattgt ttttatgtgt ggttgtccta gttcagagtg
    31921 atctgtcctc tgggtttacg caaagttatc cacaggcact gtgcatttaa aaaacttatc
    31981 ttttcttctt gatcttaaaa acttaaaaac ttagagcgtc gtaacattat gataaatata
    32041 ataaaaaaac gctaaacatg agaagatttt taacgtaagg tgagaggatc tttaacataa
    32101 ggtgagaaga tttttaagta agggtgagaa gatttttcac taaagatgag aggattttta
    32161 acgaaaggtg agaggatttt taagtacatc cacaggctaa aaaaatatca tgtaaaacat
    32221 gatgttatga attcattttg atgtgaatac ataaagatct ttatatctaa aggtgataag
    32281 ttttttaact aaaggttgta atgcattgtt gtcatacaac ctttataggg ttatcattta
    32341 gccaagtgat acgacttatc tata
//
