LOCUS       NZ_CP056261            34519 bp    DNA     circular CON 31-MAR-2024
DEFINITION  Klebsiella aerogenes strain RHBSTW-00898 plasmid pRHBSTW-00898_2,
            complete sequence.
ACCESSION   NZ_CP056261
VERSION     NZ_CP056261.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15148733
            Assembly: GCF_013727635.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella aerogenes
  ORGANISM  Klebsiella aerogenes
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 34519)
  AUTHORS   AbuOun,M., Jones,H., Stubberfield,E., Gilson,D., Shaw,L.P.,
            Hubbard,A.T.M., Chau,K.K., Sebra,R., Peto,T.E.A., Crook,D.W.,
            Read,D.S., Gweon,H.S., Walker,A.S., Stoesser,N., Smith,R.P.,
            Anjum,M.F. and On Behalf Of The Rehab,Consortium.
  TITLE     A genomic epidemiological study shows that prevalence of
            antimicrobial resistance in Enterobacterales is associated with the
            livestock host, as well as antimicrobial usage
  JOURNAL   Microb Genom 7 (10) (2021)
   PUBMED   34609275
REFERENCE   2  (bases 1 to 34519)
  AUTHORS   Shaw,L.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2020) Nuffield Department of Medicine, University
            of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.7
            Assembly Name                     :: WTP1 T3-00898
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 85.0111481093368x
            Sequencing Technology :: Hybrid: Illumina and OXFORD_NANOPORE
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013727635.1-RS_2024_03_31
            Annotation Date                   :: 03/31/2024 05:03:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,270
            CDSs (total)                      :: 5,148
            Genes (coding)                    :: 5,071
            CDSs (with protein)               :: 5,071
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 36 of 77
            Pseudo Genes (incomplete)         :: 40 of 77
            Pseudo Genes (internal stop)      :: 11 of 77
            Pseudo Genes (multiple problems)  :: 9 of 77
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP056261.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..34519
                     /organism="Klebsiella aerogenes"
                     /mol_type="genomic DNA"
                     /strain="RHBSTW-00898"
                     /isolation_source="Wastewater influent sample"
                     /db_xref="taxon:548"
                     /plasmid="pRHBSTW-00898_2"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
     gene            join(34450..34519,1..593)
                     /locus_tag="HV316_RS26010"
                     /old_locus_tag="HV316_26020"
     CDS             join(34450..34519,1..593)
                     /locus_tag="HV316_RS26010"
                     /old_locus_tag="HV316_26020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516402.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHDL
                     LSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVSDI
                     VVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDLDKL
                     LRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIGIL"
                     /name="division plane positioning ATPase MipZ"
     gene            693..977
                     /locus_tag="HV316_RS26015"
                     /old_locus_tag="HV316_26025"
     CDS             693..977
                     /locus_tag="HV316_RS26015"
                     /old_locus_tag="HV316_26025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001185481.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVAGKPKLMNFRL
                     PAYFEEILEAEAQRTGQSKTTVLKAALAAFDNLDENLKNHWLLESAKLG"
                     /name="hypothetical protein"
     gene            1184..1495
                     /locus_tag="HV316_RS26020"
                     /old_locus_tag="HV316_26030"
     CDS             1184..1495
                     /locus_tag="HV316_RS26020"
                     /old_locus_tag="HV316_26030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482050.1"
                     /translation="MFIFRYIKALINIYLLYIQPILGMFLIGIGLWGFYAPDEGTCTNL
                     NIELCTVSTIDVLKPAIFVFLGIITVAGWYFTELQPKLRGEGKYMKVKTGVKPEDFVK"
                     /name="hypothetical protein"
     gene            1531..1815
                     /locus_tag="HV316_RS26025"
                     /old_locus_tag="HV316_26035"
     CDS             1531..1815
                     /locus_tag="HV316_RS26025"
                     /old_locus_tag="HV316_26035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482052.1"
                     /translation="MNKSWLEQQVQTEKIKKVQEEKKDSTIQKGLYRVRIKSKYRWDLW
                     ENDFRVVIAYSKDDAELKFTEMTGFNEHYYIESIEKITLSDIEKVLLEN"
                     /name="hypothetical protein"
     gene            complement(2115..2468)
                     /gene="ddp1"
                     /locus_tag="HV316_RS26030"
                     /old_locus_tag="HV316_26040"
     CDS             complement(2115..2468)
                     /gene="ddp1"
                     /locus_tag="HV316_RS26030"
                     /old_locus_tag="HV316_26040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_228725283.1"
                     /translation="MKYQVKEFINEKYSKAVNILKDNLKEHYHIFYGLRLSEILFPASE
                     YGSEMFFQEFEAINSVILPLVIFDLIDRKPIMVIGFGEVSGVDSLVDSGIEVVSLDGLS
                     DLLMNKKLNPLFD"
                     /name="ddp1"
     gene            complement(2656..3099)
                     /locus_tag="HV316_RS26035"
                     /old_locus_tag="HV316_26050"
     CDS             complement(2656..3099)
                     /locus_tag="HV316_RS26035"
                     /old_locus_tag="HV316_26050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482056.1"
                     /translation="MAKIYDFPQGAERGKLKKEIIRERKKRLREKNGNPVIRHAKWFWF
                     YLRLATAGALHLVSVITLAILGAFSKAIFWIGGLLCVVTWFHLERQFWTPQNFTIPVIV
                     TLWGLSLFATPLMELLNKKMPWYRLLVPDAKHTSTEAINDDQP"
                     /name="hypothetical protein"
     gene            complement(3108..4013)
                     /locus_tag="HV316_RS26040"
                     /old_locus_tag="HV316_26055"
     CDS             complement(3108..4013)
                     /locus_tag="HV316_RS26040"
                     /old_locus_tag="HV316_26055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488386.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_061800704.1"
                     /translation="MRLKVMMDVNKKTKIRHRNELNHTLAQLPLPAKRVMYMALAPIDS
                     KEPLERGRIFNIRAEDLASLAKITPSLAYRQLKEGGKILGASKISLRGDDIIALAKELN
                     LPFNSKNTPDELDLNITEWIAYSKDEGYLSLKFTRTIEPYISSLIGKKNKFTTQLLTAS
                     LRLSSQYSSSLYQLIRKNYSNFKKKNSFVISIEELKDELIAYTFDGDGNTEYKYPEFPI
                     FKRDVLNKSIAEIKKKTEISFIGVSVFEKEGRKVSKLQFDFIVDEDEFSGNGDDLLTAF
                     SEEDSAFLKEFDKAVPPKKK"
                     /name="replication initiation protein"
     gene            5402..5917
                     /locus_tag="HV316_RS26045"
                     /old_locus_tag="HV316_26060"
     CDS             5402..5917
                     /locus_tag="HV316_RS26045"
                     /old_locus_tag="HV316_26060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="WP_001549904.1"
                     /translation="MNIQEALNVFGLSGDLTEKDIKAAYKKAALKYHPDRNPLGAELMK
                     AVNAAFDFLMANIDKINQFQSTDENARYNYGEDLEKVLNTLSGLTGIVYEVIGNWVWIS
                     GETKEHKDILKEMGCKWASKKKQWFYRPEEHKSRWNRKEHSIEEIREMYGTAGKRKASG
                     WRRVEASA"
                     /name="DnaJ domain-containing protein"
     gene            5976..6212
                     /locus_tag="HV316_RS26050"
                     /old_locus_tag="HV316_26065"
     CDS             5976..6212
                     /locus_tag="HV316_RS26050"
                     /old_locus_tag="HV316_26065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_065806172.1"
                     /translation="MKNKTITEAELINIFESYGAYILPDEIEVTAKECNENGSVLHRGL
                     NAEGWAHLFAKEEAYQQECEAQEAASDDGYFDE"
                     /name="hypothetical protein"
     gene            6273..6824
                     /locus_tag="HV316_RS26055"
                     /old_locus_tag="HV316_26070"
     CDS             6273..6824
                     /locus_tag="HV316_RS26055"
                     /old_locus_tag="HV316_26070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482058.1"
                     /translation="MKEQKNFFERYKPVFEIVCRILGSGWRVNLLDDCQYRIKLTSPQF
                     KNYSIHIRMEKGRLVIIGSVDSRSWRSPYHTCKVSPERNPVEIAADIEKKILTDALDNV
                     DMAREYEQQLQRKREQKQILKGMLSRLVRLESWHGTLTGFKVENGLDGNVSERGDGYEM
                     VIRGLSVDKLIKVAGFIKQL"
                     /name="hypothetical protein"
     gene            6833..7102
                     /locus_tag="HV316_RS26060"
                     /old_locus_tag="HV316_26075"
     CDS             6833..7102
                     /locus_tag="HV316_RS26060"
                     /old_locus_tag="HV316_26075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_074423240.1"
                     /translation="MNEILSDRKNKGNVTYRIVVSEDATRLFIELEKLMKVRSKEEDKK
                     TTKKVVFQKSFYHEEFCNVKDEIDDPILLQFYSDTIVKVQNHEF"
                     /name="hypothetical protein"
     gene            7092..7334
                     /locus_tag="HV316_RS26065"
                     /old_locus_tag="HV316_26080"
     CDS             7092..7334
                     /locus_tag="HV316_RS26065"
                     /old_locus_tag="HV316_26080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000008707.1"
                     /translation="MSFKPTPEEVKQARIKAGFTQQEAAERFGFTLSAWQAKETSGKTS
                     RGLAAGTYELLLLLADEHPDYQLVKREKNQDKVTK"
                     /name="hypothetical protein"
     gene            7428..7766
                     /locus_tag="HV316_RS26070"
                     /old_locus_tag="HV316_26085"
     CDS             7428..7766
                     /locus_tag="HV316_RS26070"
                     /old_locus_tag="HV316_26085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482059.1"
                     /translation="MNTYVITFQALNTKKEKITCSAFFHSETLFLAVHSFEDKNRGRGY
                     VITSASELLSEELTAKNSLKKNINFWFNECGLSKSEVINEVTNWKNFAYTLKELEEAKN
                     EAIRELRS"
                     /name="hypothetical protein"
     gene            7841..8005
                     /locus_tag="HV316_RS26075"
                     /old_locus_tag="HV316_26090"
     CDS             7841..8005
                     /locus_tag="HV316_RS26075"
                     /old_locus_tag="HV316_26090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_162838210.1"
                     /translation="MSERMLSAIQTVEKGGRPVFPLMPFSAFPEYMALLRKALEKKETK
                     ALIKKQEVL"
                     /name="hypothetical protein"
     gene            8002..8259
                     /locus_tag="HV316_RS26080"
                     /old_locus_tag="HV316_26095"
     CDS             8002..8259
                     /locus_tag="HV316_RS26080"
                     /old_locus_tag="HV316_26095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482061.1"
                     /translation="MKKQEFLDFISAEQRRGAVRFSLGFNSKGEIVLHWTNEAGLRDWS
                     ILSGNRGKSPSQANRERMSNLRRWLHDARQGMEGDTPEAE"
                     /name="hypothetical protein"
     gene            8599..9144
                     /gene="ddp1"
                     /locus_tag="HV316_RS26090"
                     /old_locus_tag="HV316_26105"
     CDS             8599..9144
                     /gene="ddp1"
                     /locus_tag="HV316_RS26090"
                     /old_locus_tag="HV316_26105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="WP_181482073.1"
                     /translation="MKKVQFRIEESQHDDLLDCLKTLYPDEPGLTVAKGMKLFASALLK
                     SKVKNEDVNVSKDNYDFIKTTMYLTGKQRTLIEKAAHRHGWNLSRECRYRIQTTLENEL
                     DFFDQELLVMNRCRNAIDKIGRNFHYIIVNDNARVLDKDGFYQDAERLSTEIMSLKSEF
                     ENYIMLCKGRTVSNKVEV"
                     /name="ddp1"
     gene            9147..10307
                     /gene="mobP1"
                     /locus_tag="HV316_RS26095"
                     /old_locus_tag="HV316_26110"
     CDS             9147..10307
                     /gene="mobP1"
                     /locus_tag="HV316_RS26095"
                     /old_locus_tag="HV316_26110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP1 family relaxase"
                     /protein_id="WP_181482063.1"
                     /translation="MGVYVDKEFRVKRKSSEAGRKSAFAHKVKNGGKNYQRNVQERINR
                     KGASKEVVVKISGGAITRQGVRNSIDYMSRESELPVMSESGQVWKGDEIQEAKEHMIDR
                     ANDPQNVFDDKGKENKKVTQNIVFSPPVSAKVKPEDLLESVRKTMHKKYPNHRFVLGYH
                     NDKKEHPHVHVVFRIRDNDGKRADIRKKDLREIRTGFCEELKLKGYDVKATHKQQHGLN
                     QSIKDAHKTAPKRQKGVYEVIDVGYDHYQNDKTKPKQHFIKLKTLNKGVEKTYWGADFG
                     ELTTRENVKKGDLVKLKKLGQKEVKIPALDKNGIQYGWKTAHRNEWQLENLGVKGIDRT
                     TSSSKELVLNSAEMIKKQQLQMRNFSQIKQAMIQSEQKVKIGIRLG"
                     /name="mobP1"
     gene            10661..11170
                     /locus_tag="HV316_RS26100"
                     /old_locus_tag="HV316_26115"
     CDS             10661..11170
                     /locus_tag="HV316_RS26100"
                     /old_locus_tag="HV316_26115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455437.1"
                     /GO_process="GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]; GO:0140673 -
                     transcription elongation-coupled chromatin remodeling
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_181482065.1"
                     /translation="MEWYVLQFTTTRFAAVFAHLERLNFSYFCPMETERYRRPDKIISY
                     RERRLPLFPGYLFIQADFEEVHSTTITAIPYVQRFISFGGEPLPVPEDVMAELLYRQSH
                     TTAQANLLRKSIPHEFAEILLMDNPQQRSMAFIHYITERSLTHKMKRKKNDCYPKKNRN
                     ETQAPT"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            11394..12038
                     /locus_tag="HV316_RS26105"
                     /old_locus_tag="HV316_26120"
     CDS             11394..12038
                     /locus_tag="HV316_RS26105"
                     /old_locus_tag="HV316_26120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_181482067.1"
                     /translation="MLSTTAFAALALQCAASVHPDTAHEVARVESGFNPYAIAEIIPKV
                     ERKPGDKGVVSYFPKTKEAALQIVNQIESRNHRYSVGLMQITSTNFANFNTTAEKMFDP
                     CENLKVSEQILVDCYKRGGDILRGLSCYYSGNPETGTKPESDFNNTSYIQRIGFNPPDN
                     KKNWVVPSVKYAIRKENVKQSIKPKEVTVYPQYAMRGTVLDEKETNDVKTQ"
                     /name="lytic transglycosylase domain-containing protein"
     gene            12022..12312
                     /locus_tag="HV316_RS26110"
                     /old_locus_tag="HV316_26125"
     CDS             12022..12312
                     /locus_tag="HV316_RS26110"
                     /old_locus_tag="HV316_26125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_021542857.1"
                     /translation="MLKLNKRYLTLSVFMAALMLCVAEPAFADDVSTKTTGFLQKIIDF
                     LTDIRKPAITIIALVIGYIAIFSRQHASWIYPLAIGIIIFIIAPYLPDWLS"
                     /name="TrbC/VirB2 family protein"
     gene            12337..15090
                     /locus_tag="HV316_RS26115"
                     /old_locus_tag="HV316_26130"
     CDS             12337..15090
                     /locus_tag="HV316_RS26115"
                     /old_locus_tag="HV316_26130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_181482069.1"
                     /translation="MSTVFKGLTRPALIRGLGVPLYPFLGMCVICVLLGVWIHEAMYAL
                     ILPGWYAIKRVTKIDERFFDLLYLRMQIKGNPLANKRFNAVHYAGSSYDAVDISKVDNF
                     MKLKDQSSLEELIPYSSHITDNLIVTRNHDLLATWQIDGAYFECVDEADLALLTDQLNT
                     LIRSFDGKPVTFYTHRIRVRKEVRPVFDSKIPFVNRVMNDYYESLSAAEYFENKLYLTV
                     CYKPFSAEDKVTHFLSRKKGNKNIFEEPINDMNEICGRLSTYLSRFHSRRLGLYEENNI
                     VYSEQLTLFQKLLSGRWQKVRVTNSPFYTYLGGKDLFFGNDAGQITASDHARYFRCIEI
                     KDYFQETDAGIFDALMYLPVEYVQTSSFTPIDKQSAIKALDDQIDKLEMTDDAAKSLLA
                     DLKVALDMVSSGYISFGKSHQTLIVYADSPERLVKDTNIVTTTLEDLGLIVTYSTLSLG
                     AAYFAQLPGNYTLRPRLSSISSLNFAEMESFHNFFTGKEKGNTWGNNLITLGGSGNDIY
                     NLNYHMTTEHQNYFGKNPTLGHTEILGTSNVGKTVVMMTKAFAAQQFGTPESFPPERKL
                     KKLTTVFFDKDRAAEPGIRSMGGAYFRVKEGEPTGWNPAALPPTKRNISFMKDLVRLLC
                     TLNSEPLDDYQNRLISDAVERLMQRSNRSYPISKLRPLILEPDDTETRRHGLKARLNAW
                     VQGGEFGWVFDNPDDTFDVDNLDVFGIDGTEFLDNKVLSSAASFYLIYRVTMLADGRRL
                     LIYMDEFWQWINNEAFRDFVYNKLKTARKLDMVLVVATQSPDELIKSPIAAAVREQCAT
                     HIYLANPKAKRSEYVDELEVRELYFDKIKAIDPLSRQFLVVKNPQRKGESDDFAAFARL
                     DLGKAAYYLPVLSASKPQLELFDGIWKEGMKPEEWLDTYLERANLI"
                     /name="VirB3 family type IV secretion system protein"
     gene            15100..15870
                     /locus_tag="HV316_RS26120"
                     /old_locus_tag="HV316_26135"
     CDS             15100..15870
                     /locus_tag="HV316_RS26120"
                     /old_locus_tag="HV316_26135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000716326.1"
                     /translation="MKKHIVAALIASVTVISGAQAGVPVAIDANPEWAVEAQRWTERLK
                     QWQDTVNHYQKQINAYKQELLTKTGIRDVQGLVQSAQSVSKELENIYDQGNSFIDDYIK
                     NPEATLSEQARSLLADYKVTNTCKGLGYTGDLVRGCEASFLSQLAGIEYGNKLESKLRE
                     DNQEMADLIDQVKNAQDTKATQDATNAVSLASLKFNKLKFQYEMYRDKQRDLAEYKEKM
                     LQAAFQEKQLGAVNKETPVVDYKAAFEQQSYEMN"
                     /name="type IV secretion system protein"
     gene            15880..16137
                     /locus_tag="HV316_RS26125"
                     /old_locus_tag="HV316_26140"
     CDS             15880..16137
                     /locus_tag="HV316_RS26125"
                     /old_locus_tag="HV316_26140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000759841.1"
                     /translation="MKKYGLVAALGLTFFLTGCEEVKSVDWWQSHVDDATKKVAECKKS
                     GSDSENCKNAKEGLFRYKQLHPKHVDYKDAFKNVLGKDGS"
                     /name="EexN family lipoprotein"
     gene            16149..17204
                     /locus_tag="HV316_RS26130"
                     /old_locus_tag="HV316_26145"
     CDS             16149..17204
                     /locus_tag="HV316_RS26130"
                     /old_locus_tag="HV316_26145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_181482071.1"
                     /translation="MATSRYFQAAHDVIVKTLDQSLTGQLDNFSSIASQLGKYGISIYI
                     LWYAYTTIVGKQKTAVQDFLWNLCRFWLILVFVKNMGGWLDSATQAIDGLKETFAGGDP
                     WKWVDELWEKIQQVAAYLMSKDTSKYVKTDGAIASLLTYAGGIIALLLTSIVYLAAEVT
                     IKILTITAPLFIICLSFGFLRQMFNSWLQLIFSSCFIFLFCGLAIKAGMTFLNGILTIS
                     IANADELNLISTGAQAGVAGAFMAWIIWQAKTYASQLAGVGVEGAMQGAAAMGIGAGVF
                     GASRMGRNLLGMGKNAGIGAWKGVRRQDGGFNQSPGVSGKLGNLTGQGVNIGAKRLRQA
                     AIDAAKKKYGG"
                     /name="type IV secretion system protein"
     gene            17399..18127
                     /locus_tag="HV316_RS26135"
                     /old_locus_tag="HV316_26150"
     CDS             17399..18127
                     /locus_tag="HV316_RS26135"
                     /old_locus_tag="HV316_26150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004199085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_181482017.1"
                     /translation="MGFKLSELKLPGFNKKKEVTDSSTTFEEKNVLMQEKMNRIYKFGG
                     IAGMAVGVLSLLALNGALPLKSTVVEAYLINGVTGVAERLTSVKKENLSENEALAKYFI
                     TQYVKRREGYNYFSLQHDYDYVLLYSAENVATDYNALINGNQSPKVIYNKAEKTASVQD
                     NPSVIISPSSRRDDKDMGAYIRFKLTIRNVATGQDDYEYWNVRLTYRIEPQVEMASGDR
                     NNNPLKFVVTSYVRDKEVKG"
                     /name="type IV secretion system protein"
     gene            18133..19062
                     /locus_tag="HV316_RS26140"
                     /old_locus_tag="HV316_26155"
     CDS             18133..19062
                     /locus_tag="HV316_RS26140"
                     /old_locus_tag="HV316_26155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000783379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_181482019.1"
                     /translation="MKMNKGALIVALLLVSHVCHAAVTPAASRFDPRNQIVSYNPQNTT
                     VINSAVGYTTTLVFDEDETVISARTGFPQGWEVNKEDNLVYLEVKPVKQTVQKNSTDDN
                     GNQSSEVVSVALDPENDLERWRTNLFVRTTKRNYSMELNARTFRQPDKIAFVVNYQYPQ
                     ERRKEQAEIEKKRIEALNKRQEEQAINRSLENAKSPRNWDYWKRVADGSQSISPDYAYD
                     DGRYTWFGFSSLKKIPSIFVLSGEQETLTNPVVKNSGSFTVVGVPVDQRFVLRMGNQVV
                     GVENRGFGKVRLPAGDTVSPNVEKEVIQ"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            19059..20261
                     /locus_tag="HV316_RS26145"
                     /old_locus_tag="HV316_26160"
     CDS             19059..20261
                     /locus_tag="HV316_RS26145"
                     /old_locus_tag="HV316_26160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="WP_181482021.1"
                     /translation="MSEQENKIPTAVEIEQALRERHQKEIEQSDKTDKEDEDDGKSVKR
                     LGIEKLKKSRKGLVIIVAAFLLLAAGVSVYYIPSIIRATSSGDEKPASNAVSTGSVKRA
                     TGLSDDVDPFNTRAEPAKTEERKESSDKAETPPEKVQQNFSRALDVAYGGSSSASSNSG
                     GSSSTASNTRNEGDGSDKQAEVQPVNAGQPAQLSKITRVPYDPNLFIPENTAIKCSLDR
                     RFISDLAGKLVCTINEDIYSANRNVKLIEKGTAAYLMYKTGTFNHGQGAVFIAATKLRT
                     RKEPFIDIPLIDTQAAGALGEAGASGWIDTHFADRFMGAMMVGMIPDVAQAASGAAKSN
                     KDNQTDYTANSRQAFADIAREAFANSVNIPPTLYKNQGEIITLIVGQDLDFSSIYKLKM
                     K"
                     /name="TrbI/VirB10 family protein"
     gene            20273..21304
                     /gene="virB11"
                     /locus_tag="HV316_RS26150"
                     /old_locus_tag="HV316_26165"
     CDS             20273..21304
                     /gene="virB11"
                     /locus_tag="HV316_RS26150"
                     /old_locus_tag="HV316_26165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058463.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_228725282.1"
                     /translation="MLKENIHLAYELVNDYFHKPLNEIEGLTEIAVNRPNELFIKVRGK
                     WQQHELKMDFLDCMSFAGAISDYHDGGSVTPEYPLRSVTLPGGERVQIVIPPATERETV
                     SITIRKPSSVFIDHDTFVKQGFYSRLNQGVEFRDKEDELSLMFKDNCFERFVPECLVKG
                     KTMVFCAGTGAGKTTFANACLQYIPHHLRCISIEDTDEAKFRFHKNHVKLYYPSEGESS
                     TVSSASLLRSGFRMNPDRILMTEVRGAEAWDFLKGSSSGHAGNLTTVHESTPEDAVLGL
                     VQRCYMNPECQNLPYNIILRRVLSNVDVIMSIKYIDEEDNRFASGIYYRDIHFQEYFEK
                     LKE"
                     /name="virB11"
     gene            21307..23142
                     /locus_tag="HV316_RS26155"
                     /old_locus_tag="HV316_26170"
     CDS             21307..23142
                     /locus_tag="HV316_RS26155"
                     /old_locus_tag="HV316_26170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053816.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_181482023.1"
                     /translation="MSLKLPDKGQWAFIGLVMCLVTYYTGSVAVYFLNGKTPLYIWKNF
                     DSMLLWRIITESNIRTDIRLTAIPSLLSGMVSSLIVPVFIIWQLNKADVALYGDAKFAS
                     DNDLRKSKLLKWEKENDSDILVGAYKGKYLWYTAPDFVSLGAGTRAGKGAAIGIPNLLV
                     RKHSLIALDPKQELWKITSKVREKLLGNKVFLLDPFNSKTHQFNPLFYIDLKAESGAKD
                     LLKLIEILFPSYGLTGAEAHFNNLAGQYWTGLAKLLHFFINYDPSWLGEFGLKPVFSIG
                     SVVDLYSNIDRELILSKREDLEATKGLDENALYHLRDALTKIREYHETEDEQRSSIDGS
                     FRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAEDMSLAYDFLNLFFNFVVE
                     VTLRENPDFDPTLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNE
                     IYGVEGAKTLMSAHPCRIIYAVSEEDDAKKISEKLGYITTKSTGSSKTSGRSTSKSSSE
                     SEAQRALVLPQELGTLDFKEEFIILKGENPVKAEKALYFLDPYFMDRLMMVSPKLTELT
                     ASLNKTKKVLGVKGLKYPSKEKMLSVGELESEVLL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            23139..23531
                     /locus_tag="HV316_RS26160"
                     /old_locus_tag="HV316_26175"
     CDS             23139..23531
                     /locus_tag="HV316_RS26160"
                     /old_locus_tag="HV316_26175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_181482025.1"
                     /translation="MKKMLMVGVLFLSACSSPPEPPQVDWEQKPETVNTQLMDWQPTYS
                     IIKSDKVDSSWVKVIHDFRPENRLYDDAVFYSVAHSDSVIVETSNGTDFFTAKNWLRAN
                     GANGVIQYRYKMNCLSCRTTSIYLSR"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            23619..23933
                     /locus_tag="HV316_RS26165"
                     /old_locus_tag="HV316_26180"
     CDS             23619..23933
                     /locus_tag="HV316_RS26165"
                     /old_locus_tag="HV316_26180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_181482027.1"
                     /translation="MKKTVTTAVLLCAFAAGAAHAEEKADPNDPCAMVLCLAGKLDGSS
                     PAECDPMYKSFMSIRKKNKHGFLPNHTADARKKKLNECPAADAGTVNKIISSFGRLKSF
                     "
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            24019..24342
                     /locus_tag="HV316_RS26170"
                     /old_locus_tag="HV316_26185"
     CDS             24019..24342
                     /locus_tag="HV316_RS26170"
                     /old_locus_tag="HV316_26185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004208538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482029.1"
                     /translation="MKVINAPDARSVRVAGIEIIDSVKAVASVFTEILLFMVWFPAIIY
                     GLYRVIIVLWDDSLKPQSLMEFINFMVELYSYVLPSLAVIAVVLIVILSSFKVFSKVWR
                     KSC"
                     /name="hypothetical protein"
     gene            24336..24752
                     /locus_tag="HV316_RS26175"
                     /old_locus_tag="HV316_26190"
     CDS             24336..24752
                     /locus_tag="HV316_RS26175"
                     /old_locus_tag="HV316_26190"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482030.1"
                     /translation="MLRELSGVSRTLWRAAFFSLVKAPAMALFIGFVFLSFNNSIADTF
                     LTSARELTGNAPPDKVQTCVFKKSKQELSPYVQKEPCVNTLTDAKDWSQSFDRSIRRIY
                     WTIALLGFFTWFCFDGMAAQLMLKIDDIWERRKK"
                     /name="hypothetical protein"
     gene            24749..25222
                     /locus_tag="HV316_RS26180"
                     /old_locus_tag="HV316_26195"
     CDS             24749..25222
                     /locus_tag="HV316_RS26180"
                     /old_locus_tag="HV316_26195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_181482032.1"
                     /translation="MKYFLYAFSLVVVILPPALFAAQIQGKVIRVLDGDTIEVLQEQQP
                     VRVRLLNIDAPEKKQPFGRWSTNQLKALLAGQSVTVSYTQTDRYGRVLGRVVTANGTEA
                     NRQQVLKGAAWVYDRYNTDNSLPALQREAQTQKRGLWADNQPVPPWEWRHKNN"
                     /name="thermonuclease family protein"
     gene            25304..26077
                     /locus_tag="HV316_RS26185"
                     /old_locus_tag="HV316_26200"
     CDS             25304..26077
                     /locus_tag="HV316_RS26185"
                     /old_locus_tag="HV316_26200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000988150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482034.1"
                     /translation="MMTESDKERFNKRICVGHVLVSADIYVTPVMTESAAEVELTVPNE
                     DYKKAMDLYERICQFALLHGEDLQGLFQTSRYYYMSCFVRDIEAFKKEFEKEEELKPLF
                     NHDKGDTAEFLISFPEKANYDDKEPVKNSFLEITQKHVDSLDELTWGDFEHRAFTGGTV
                     GFGINPNTMERINFDDERDKITKLSRKDFVASNLTDSFEDDFYVNPLFEGAQKIGEIDN
                     HPVYFNSRGFYFYWNKETEYLLESWLTFPSYPYGW"
                     /name="hypothetical protein"
     gene            26088..26678
                     /locus_tag="HV316_RS26190"
                     /old_locus_tag="HV316_26205"
     CDS             26088..26678
                     /locus_tag="HV316_RS26190"
                     /old_locus_tag="HV316_26205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6012 family protein"
                     /protein_id="WP_181482036.1"
                     /translation="MYLHIVPRLFHLMANKCHLESVTIPELDFKIEVDALSTGRPHPNK
                     NIWVGMRKGRKAINGLLLKTDKHLKWFTADYQWHIENMGLITHRVTTYIEDNEFDMVSQ
                     DIMLNGGFEQWENRRHSAYDEISPAKNQPRMESFLSNPGKRDSHDTWRVFDWGDFLELR
                     EESLLLHTIQSERLNTDFPLFNRLPSLEQAIII"
                     /name="DUF6012 family protein"
     gene            26689..27084
                     /locus_tag="HV316_RS26195"
                     /old_locus_tag="HV316_26210"
     CDS             26689..27084
                     /locus_tag="HV316_RS26195"
                     /old_locus_tag="HV316_26210"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482038.1"
                     /translation="MDFSKFDFNHDCYVDLHVGDYGSLSGLFFTGKSDLAIIEKLFTDS
                     HDWQNSFQREGRQYVMGFVDPGNVQFIAFMQHAFTKEKEHDERFYRENGYYEQSHDFFN
                     IWFDNDVSDVQISFPLLKAVDKASELI"
                     /name="hypothetical protein"
     gene            27094..29421
                     /locus_tag="HV316_RS26200"
                     /old_locus_tag="HV316_26215"
     CDS             27094..29421
                     /locus_tag="HV316_RS26200"
                     /old_locus_tag="HV316_26215"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549937.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_181482040.1"
                     /translation="MRLFIAEKPSLAKAIFEGLGGNPNTEKKNGYFEHGSDVVTWCYGH
                     MLELYDPQDYDEKYSNWRFSDLPIKAVYPPKYKIKPESEAQTRIILSLIDKADSIVHSG
                     DPDDEGCLLVDEILGYAGNNKPVQRLLVADLNLAPVQKSLANLQPNDKFRGMTLSALAR
                     SLCDQGFGYNMTRGCTLKGREKGYDGVLNVGRVQSAVLGLVNMRTLANQNHTESFYYDV
                     FASLSMNGHQIKAKYQTTDDDQIDEKKRLISEAQAEHIAGRVTGKDAIVTIATTKPENT
                     KPPLPLNLSTLQQLCAKRFGYSAKDTLDVMQGLYETHKLLTYPRSDNRYLSDEHYYQAG
                     EIAAAIAATVPELASAIVDMDKGQKHKAFNASKIEAHHAIIPTTKSGAGIQLNEKERNV
                     YNLVSVYFIGLFYPDAIRNKTKIHFDIKGDTFTATQSVLVQKGWEALGKDNDDEEETED
                     AGTDGFDLSSLKFNDSGLCESADVDKKKTTPPRYFTESTLLAAMTSAAKFIDDPALRKA
                     LEAKDEGSSDRGSIGTEATRAGILEKLAANTGLISIEKEKGYSELVWKTTKQGQEFCAA
                     LPPEITKPDISALWAEKQSQIKAGELTVEEFIKENDEYVQGVIDELDRNGISISSNATP
                     CPVCNNGFLRKRKGQNGFFWGCSCYPECKTTFPDKDGKPDMEAKSRSEGSMSRLEAPCP
                     SCSKEIIIRPKGFFCSGCEFKIWSEVSGKKLTQNQVEMLIKKGKTGEIKGFTSNKTGKK
                     FDAAIVLQDKATGKLGFQFSKK"
                     /name="type IA DNA topoisomerase"
     gene            29433..29888
                     /locus_tag="HV316_RS26205"
                     /old_locus_tag="HV316_26220"
     CDS             29433..29888
                     /locus_tag="HV316_RS26205"
                     /old_locus_tag="HV316_26220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549938.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_181482042.1"
                     /translation="MSENETFDATRKLLLNIRSVRVFARETSFEQLLEMQEKLNAVIEE
                     RREEAEREAAEREERERKRQELLQLIAGEGFSPEELLGLTEDTPKTRKKTLPKAPPKYQ
                     FDENGETKYWSGRGRTPKPIDEALKAGRSLDEFLIKEDASSSVGDEK"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(29926..30576)
                     /locus_tag="HV316_RS26210"
                     /old_locus_tag="HV316_26225"
     CDS             complement(29926..30576)
                     /locus_tag="HV316_RS26210"
                     /old_locus_tag="HV316_26225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242661.1"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="WP_181482044.1"
                     /translation="MDIKPNSVIHLEPGETLPGYTNLKPVPDKYLDELKALINKLNTQS
                     GNIYLKLKQMYAFLDRFNKEFVSTFTSCQKGCSSCCKIDVHLTALEATHIAQASKLTAR
                     DNPLTTGHESKCPFLSEKGTCSIYNYRPLLCRTYHVLTPPEMCNDPDAQVMQYGSQSAN
                     MGNHIYKTIAEWIYFQTYHCTGKLETKDIRDYFPYPREDIQRFLHHNPPRPFC"
                     /name="YkgJ family cysteine cluster protein"
     gene            30566..30832
                     /locus_tag="HV316_RS26215"
                     /old_locus_tag="HV316_26230"
     CDS             30566..30832
                     /locus_tag="HV316_RS26215"
                     /old_locus_tag="HV316_26230"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482079.1"
                     /translation="MISIAFASFILLALVVYLTLKQALNNGKASNPAVNQVCQQTSFLQ
                     PVWPLIFASNLTRSMLALGLKLPAKKIAASKGVVYIICIVRYR"
                     /name="hypothetical protein"
     gene            30844..31077
                     /locus_tag="HV316_RS26220"
                     /old_locus_tag="HV316_26235"
     CDS             30844..31077
                     /locus_tag="HV316_RS26220"
                     /old_locus_tag="HV316_26235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004196202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021542838.1"
                     /translation="MNYVDIARVWRQHNQEHADSGVVLIWDGKVYCWKNILRDPQHERP
                     GVIAVDTEENVFIAEGGNEYDGAKCWVVFQES"
                     /name="hypothetical protein"
     gene            31080..31904
                     /locus_tag="HV316_RS26225"
                     /old_locus_tag="HV316_26240"
     CDS             31080..31904
                     /locus_tag="HV316_RS26225"
                     /old_locus_tag="HV316_26240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="WP_181482077.1"
                     /translation="MTRATERAYSELQQAFDFYNQRLFDGELPDCLITFQRGKNTMGYF
                     SYRRFVAADGSGRMIDEIALNPEYFPVYPLIEVMQTLVHEQCHMWQYHYGNPSRKTYHN
                     AQWAAKMESIGLMPSSTGRPGGAKIGQKINDYPIPGGRFQRVTLELFQGQFALSWFDRF
                     PVQVEQQKDMTAVIEQWRETLAQAHQNAESGIDIEAVLSMALLPSVSPQNGNGDSGDMA
                     GSNDNGLPVAAFEDKPKKNKVKYQCRGCGAAVWGKAGLNIECGDCELAFIEN"
                     /name="SprT-like domain-containing protein"
     gene            32015..32275
                     /locus_tag="HV316_RS26230"
                     /old_locus_tag="HV316_26245"
     CDS             32015..32275
                     /locus_tag="HV316_RS26230"
                     /old_locus_tag="HV316_26245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016193173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181482046.1"
                     /translation="MGHYTIRTNDDEDQAIKKAQEATGQASASKTFMTAILELQRNRDE
                     IAQLRRELAQEQAKNKELVASVKQFRNSMNAMFELAGNNKS"
                     /name="hypothetical protein"
     gene            32831..32926
                     /gene="dqlB"
                     /locus_tag="HV316_RS26610"
     CDS             32831..32926
                     /gene="dqlB"
                     /locus_tag="HV316_RS26610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021542841.1"
                     /translation="MVNLLIIVLRAVAALANALIAILELIRQFID"
                     /name="dqlB"
     gene            complement(33100..34068)
                     /locus_tag="HV316_RS26235"
                     /old_locus_tag="HV316_26250"
     CDS             complement(33100..34068)
                     /locus_tag="HV316_RS26235"
                     /old_locus_tag="HV316_26250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122497.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_181482048.1"
                     /translation="MTQTVPKGFVRAYLRASTTEQDATRALDTINTFAIERGLSICNYY
                     IENESGSKLERPELFRLLKDCQQNDVLLVEDVDRLSRLVGEDWNTLKKMIRQKDIRVVA
                     VNVPTTWLASGHNDFDSRMFSAINDMLLDMLAAVARRDYEQRRERQQQGIARAKREGKY
                     KGRQVNQSRYDAINRLIASGSSWSQVQKVLGCSRATISKAVRQIKSSRQPSAPEPETRL
                     SAILWVPVANGSKFTRGKKKVKEEIAWLIEADFEGEVLDNNEYRLFFTYENEEDLKEQI
                     DDLFREINMFADMRNCVVDDMTLTNEKTGKSWNEYDGGWYE"
                     /name="recombinase family protein"
     Typing          complement(3109..3998)
                     /name="IncX3"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.96"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9148..10304
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="97.927"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12938..15087
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="89.958"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          16150..17201
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.715"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17400..18124
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.174"
                     /coverage="100.0"
                     /evalue="3.57e-144"
     Typing          18134..19059
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.058"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          21308..23103
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="94.658"
                     /coverage="98.0"
                     /evalue="0.0"
ORIGIN
        1 gctcaatgct ggtcaacaaa ggtaagtcgg taattatcct gaagacagat aaaaaccacg
       61 atctgttgag ctggaacgaa aagcggacag ataacggctt actcactatc ccggttcacg
      121 cagcttacgg aaacgtcagc aacgaaatta agcgccttag taagctgtgt gaagtcctca
      181 ttgtcgattg ccccggccat gacagccagg agttccgtag cgccctgaca gtatcagata
      241 tcgtggtaac actggttaag ccgtcctctg atttcgaaag cgaaacactg accagtgtta
      301 cagagaaaat ccgcaccgct cagaaagcta acgcagctct ggaaccgtgg gtgctgttca
      361 ccagaatcaa ctcagcgaaa ccccgccaca gaaaagcggc cattgatctg gataaattac
      421 tgcgttcgga caacatctgg attcaacctc tgaaaacccg gatatccgag ctggatgtgt
      481 atgaaagcgc ctgtaatgaa ggggcagggg tacatgacgt tagccgggca tcgagccttt
      541 caacagcgaa agcacagatt gaacttgtgg cacaggaaat tggcatttta tagaaatatc
      601 aagaagattc atcaacatct ttacattgta aatacaccat aaagatacta tgatatttac
      661 aattaatgca taccgtacaa ggggaaattt tcatggcttt aaaactaaac cgtccgaaca
      721 tcgatgaatc tcagcaacca gcaacaaacg cagaaacagc gcgttttatc tccggcgcta
      781 ccagagcgcc tgtagcgggt aaaccaaagt tgatgaactt cagactgcca gcgtactttg
      841 aggagatcct ggaagcggag gcgcagagaa caggccagag caagacaacc gttctaaagg
      901 cagcgctggc cgcattcgat aacctggacg agaacctgaa aaaccactgg ctgcttgaat
      961 ctgcaaaatt agggtagcgt tatggctaag aaaaagagat atgttgtgat ggttagagat
     1021 aaaaccaaat acagcggcaa tcagcgatta ttagcctggt tagtatggtt cgctaacagg
     1081 cataataagg ccgttgccta tgactgcgga gaatggattg tcgaaccatc atattggtta
     1141 agaattggaa atccaaaata gaaagaaacc taaggaaaga aaaatgttca tattcagata
     1201 tattaaagct cttattaata tctacttgtt atacatccaa ccaatattgg ggatgttcct
     1261 tataggtata ggcttatggg gattctatgc acctgatgag ggaacttgta ctaatctcaa
     1321 tattgagtta tgcactgtat caactattga tgttctgaaa cctgccattt ttgtgttttt
     1381 aggcattatc accgttgccg gatggtactt taccgaactt cagccgaaac taagggggga
     1441 gggcaagtat atgaaggtaa aaacaggtgt aaaaccggaa gatttcgtta agtaaaaacc
     1501 gagcctaaag gagttaaccg tgggggattt atgaataaat catggcttga acaacaggtg
     1561 caaacagaaa aaataaaaaa agtccaggaa gaaaaaaaag atagcactat ccaaaaagga
     1621 ttgtacaggg tacgtataaa aagcaaatac aggtgggatt tgtgggaaaa tgatttcaga
     1681 gttgttattg cttattcgaa agatgatgca gagctaaaat ttacagaaat gacaggtttt
     1741 aatgagcatt actatataga aagcattgaa aaaataacgc tttcagatat agagaaagtc
     1801 ttgctggaaa actaacaggc acaaactaaa acaaaggatc caattacatg ataacaatcc
     1861 cattaccaat gttcatagca atatttatcg ttctgttgat tgggtatagt ttcgagttca
     1921 ataaatatat acgaatggta tcccttgtcc tgtttatagg attttggttt tcattcgaag
     1981 cgagtggcat tccatcattc aatatagcca gtattgacaa tactatatgg tatgcaattg
     2041 ggaaagccat tatctctata ttagcagtag gtttaggaat gctttgctta aaaaaactat
     2101 ggtcaaaaca gtagttaatc aaacaatgga ttcagttttt tattcatcaa taaatcgctt
     2161 aaaccgtcta aagaaacaac ttctatacca gaatcaacaa gtgaatcaac tccagatact
     2221 tcaccgaagc cgataaccat aatcggcttt cggtctatta aatcaaaaat caccaaaggc
     2281 aatattacac tgttaatcgc ctcaaactct tgaaaaaaca tttcagagcc gtattcgctg
     2341 gcaggaaaaa gaatctcact taatctcaaa ccataaaaaa tatggtagtg ttctttaagg
     2401 ttatccttta aaatattaac agccttagaa tatttttcgt taataaactc tttaacctga
     2461 tatttcataa aactctccaa caagaaccga ctgtaggtca ccgggcaaac gttgcggaat
     2521 ggcgtcagag acgtcatttt gcggcgtttg ccctatcctg catcgcagtg aaaagaactc
     2581 gcctcgtgcg ctacaataaa ccgatgataa aaggctgaaa gaagcactgc aagccaactg
     2641 gctaacattg ttgcttcacg gctgatcatc attgattgcc tcagtgctag tgtgctttgc
     2701 atcaggaacc agaagacgat accacggcat ttttttgtta agcaactcca tcaggggagt
     2761 ggcaaacaaa ctcaatcccc acagcgttac gattactgga atcgtgaaat tttgcggcgt
     2821 ccagaactgc cgctcaaggt ggaaccatgt aacaacacag agcaggccac caatccagaa
     2881 aatagcttta ctgaaagcac ccaggattgc cagagtaata acagagacta aatgcagtgc
     2941 gccagccgta gcaagacgta gataaaacca gaaccattta gcgtgccgga taaccgggtt
     3001 accgttcttt tctcgcaatc gttttttacg ttcccggatg atctcttttt ttagcttacc
     3061 tcgttcagct ccctgcggaa aatcatagat tttagccata tttcacctca cttttttttt
     3121 ggaggaactg ctttatcaaa ttcttttaga aatgcactat cttcttcact gaaagcagtc
     3181 aataaatcat caccatttcc agaaaactca tcttcatcaa caatgaagtc aaactgtaac
     3241 ttacttactt tacggccttc tttttcaaaa acagaaacgc cgataaaaga tatttcagtt
     3301 tttttcttta tttctgcaat tgatttatta agcacatccc gtttgaaaat agggaattca
     3361 gggtatttat actcagtatt accgtcacca tcgaaagtat aggcaatcag ttcatctttc
     3421 aattcttcaa ttgaaataac aaaagaattt ttctttttga agttagagta attttttctt
     3481 atcagctgat acaaagatga agagtattga ctactcagac ggaggctggc cgtaagtaat
     3541 tgtgtagtga atttattttt tttcccaatc aaactcgata tatatggttc aattgtacgg
     3601 gtgaatttaa gggataagta cccttcatcc ttagaatatg caatccattc agtgatgttg
     3661 agatctaatt catctggtgt attttttgaa ttgaagggga ggttaagctc ttttgctaag
     3721 gcaataatat catcccctct caaagagatc ttgctcgcac ctaaaatctt tccaccttct
     3781 ttcaactgcc tgtaagccaa cgaaggggta attttggcaa gggaagccag atcttcagct
     3841 ctaatattga aaattcgccc tcgttcaaga ggctctttac tatcaatagg agctaacgcc
     3901 atatacatta cacgcttagc gggtaaaggg agttgggcta aagtatggtt tagttcattt
     3961 ctgtgacgaa tctttgtttt tttattcaca tccatcataa ctttaagtct catcatgacc
     4021 tcactatttt ctccatccta ccaatcaaaa catgagattc aaattttttt tctcatgatg
     4081 tgatatgaag cgttgtacag aacgtacaat ccactcatgt ttagaagccc tgagatagta
     4141 catagcatgc tcagagagga acagcggggg aaaaatacga ataaaaaata tactgttttc
     4201 atgaagatcc gaagatctga agatcttcag atagatctgt ggattccacg tactaagctc
     4261 tcatgtttca cgtactatcc tctcatgttt aacgtactaa gctctcatgt ttaacgtact
     4321 atcctctcat gcttaacgta ctaagctctc atgtttcacg tactatcctc tcatgtttag
     4381 tgttttttcc tgttttttat cagtaactta caagacctct aagtctttaa gtttttaaag
     4441 aaaagaaaga aaagataagt cttttaatgc aaagggttgt ggataacagg cattaaaaat
     4501 tcaaaggcaa atccatgaca gcgcttgcta cagcactaga gattcagttg ctcagacgtg
     4561 accccagcgc gaaagtgctc tttgcaaccc tacagaaatt ccgcttcctc gctcactcgc
     4621 gggcttcgcc ctgtcgttcg gctgcggcga gcggtgtaat ctctctaaaa gatccagacg
     4681 cgatcctttt ccgatccaat cctaaaacgc aatcagaagc cctcagacgc gttttaacgg
     4741 cttttacccg gtcatgcttc aacggaacgg gtaaaatgcg cttagaacgt catacagcgc
     4801 gtttttacgt aacaagccaa aaattggcct gaggtgatct ccgctcgcac aggatgccag
     4861 caaaatttca caaccgttga cgttggccaa ttgttttttg ctggcaattg tcgtgcagcc
     4921 gctggcgccc ggattcattt tttgctgtca ggcaccaatc ggtttcagaa acccgccccg
     4981 taattcgctg ctaacgcatc tcataacgcg cagatacagc gccccgcgcc agtgtttcac
     5041 actgacccgg cgtaccgttc gcaagctcac gcgctaactg cgacaggcta aaaatcgtct
     5101 gatagccaga aattagcctg gcaggggtga gggggttatc gctctcattc gggtttgttg
     5161 gttcgccagg actggcgaac gtctccggcg cgatgttaca acagcgcatt atgtaactac
     5221 agttcgcgcc tcttttggaa atcccttcat gcgtggtaaa gcaatataca tctttatgta
     5281 atctttacaa tgtaaagcat taaaaatgat tccataacca tcatttgatg gtataatgaa
     5341 tttgttggtt gggaatggtt ccctgccaga ttccagaagc ccacacgggc gggagtgaaa
     5401 aatgaatatt caggaagcat taaacgtttt tggtttatcc ggtgatctga ctgaaaagga
     5461 catcaaggcg gcatacaaaa aagcggcttt aaaatatcat ccagaccgca atccattggg
     5521 tgctgagttg atgaaagcag taaatgcagc gtttgatttt ctcatggcta acattgataa
     5581 aatcaatcag tttcaaagca ccgatgaaaa cgcacgttac aactacggtg aagatctgga
     5641 aaaagttttg aatacgcttt ccggccttac agggattgtc tatgaagtca ttggtaattg
     5701 ggtctggatt agcggagaaa ctaaagaaca caaagatatt ttaaaggaaa tgggctgtaa
     5761 gtgggcatcg aagaaaaaac aatggtttta ccgtcctgaa gaacataaaa gccgctggaa
     5821 ccgtaaagaa cacagtattg aagaaatccg tgaaatgtat ggtacagcgg gtaaacgtaa
     5881 ggcgtcaggc tggagacgtg tagaagctag cgcataaccg gaacgggggc gaaagccccc
     5941 tagaacatgg caaagattga tacggagaca cgttgatgaa aaacaagacc ataacggaag
     6001 cggagctgat aaacattttt gaaagttacg gagcctacat tttaccggat gagatcgaag
     6061 ttacagccaa agaatgcaat gaaaatggtt cagtcttaca ccgtggctta aacgcagaag
     6121 gatgggcgca tctttttgca aaggaagaag catatcagca ggaatgcgaa gcccaggaag
     6181 ctgcaagtga tgatggatac tttgacgaat agtcttaaaa ctgccgtaat tcgatttacg
     6241 gcttttttgt tgagttcaaa aggctgaatc agatgaaaga acagaaaaat ttctttgaac
     6301 ggtataaacc tgtgtttgaa atcgtttgtc gaatcctggg gagcggttgg cgtgtaaacc
     6361 tgctcgatga ttgccagtac aggattaagc taacctcacc tcagtttaaa aattactcta
     6421 tacatattcg aatggagaaa ggaaggttag ttatcattgg aagcgtagac agtcgaagct
     6481 ggagaagtcc ttaccatact tgcaaagtat cgccagaacg taaccctgta gaaatcgccg
     6541 ccgatattga aaagaaaatc ctgacggatg ctttagataa tgtagatatg gcgcgagaat
     6601 atgaacaaca gttacagaga aaacgcgagc aaaaacagat cctgaaagga atgttatctc
     6661 gtttagtgcg tcttgaaagc tggcatggga cattaaccgg gtttaaagtt gagaatgggt
     6721 tagatggtaa cgtatcagaa cggggcgacg gatatgaaat ggtaattcgt ggcctgagtg
     6781 tggataagct cataaaggta gcggggttta ttaaacagtt atgaggcaaa aaatgaatga
     6841 gatcctgagc gacaggaaaa acaaaggtaa tgtaacatac aggattgttg tatctgaaga
     6901 tgcaacacgt ttgtttattg aacttgaaaa actgatgaag gtacgctcta aagaagagga
     6961 taaaaaaaca actaaaaagg ttgttttcca aaaatcattt tatcatgaag aattctgtaa
     7021 cgttaaagat gaaattgatg atccaatttt attgcaattc tattcagata ctatcgtgaa
     7081 ggtacaaaat catgagtttt aaaccaacac ctgaagaggt taaacaagca cgtatcaaag
     7141 ctggctttac gcagcaggaa gccgctgaac ggtttggttt tacgttatca gcctggcaag
     7201 ccaaagaaac atccggtaaa acatctcgcg gtttagccgc tggtacgtat gaattacttt
     7261 tgctcctggc tgatgaacat ccagattacc agctcgttaa gcgagaaaaa aatcaggata
     7321 aagtgactaa ataaattgca ttaccatcat atgatggtat aatttgtttg taggtcggga
     7381 atagttcctt accatgatcc agtagcccaa acgggcggga gactaaaatg aacacttatg
     7441 ttatcacttt ccaggcttta aacactaaga aagaaaaaat cacctgctcc gcttttttcc
     7501 attcagaaac tctcttcctt gccgttcatt ctttcgaaga taaaaatcgc ggtcgtggtt
     7561 atgtcatcac gtctgctagt gaattgttgt ccgaggaatt gacggcgaaa aattccctca
     7621 agaaaaatat taacttttgg tttaatgaat gtggtttaag taaatctgag gttataaacg
     7681 aagtaactaa ctggaagaat ttcgcatata cccttaaaga actggaggaa gccaaaaatg
     7741 aagcgataag agaactgcgg agttaattaa ttaagggtgg tatcaggttg tggaggcaac
     7801 ctgataccgt gacactcaat tccctcgcga agaatataaa atgtcggaac gcatgttatc
     7861 agcaatacag actgttgaaa agggtgggcg tccagttttt cccttgatgc cattctctgc
     7921 ttttcctgag tacatggcat tactcagaaa agccctggaa aagaaagaaa caaaagcact
     7981 gataaaaaaa caggaggtgc tatgaaaaaa caggaatttt tagattttat cagtgcagaa
     8041 cagaggcggg gagctgtccg gttttcgctg ggatttaaca gcaaagggga aattgtattg
     8101 cactggacta acgaggccgg gttaagagac tggagtatac taagcggtaa caggggtaaa
     8161 agtcccagcc aggcaaaccg ggaaagaatg agtaacctcc gtcgctggct ccatgatgcc
     8221 cgtcagggca tggaaggcga cacaccagag gcagaataac attcccgttc ctgaatcgcc
     8281 gaagccctcc cgtttacggg aggtgctttt ttgtatattc cgcaaaacag cgctcgcgcc
     8341 ccctgccagg ccattcgcgc agcgaattta tttccaccca agctagccgc aaatacgttg
     8401 tctccggtcg cagacgtacc agatcacagc catgatagcc tttcattctt tgcatttcga
     8461 tggacgctga agcacaattt gagtgtggag gtagttcact gcgatgcagg atagggcaaa
     8521 cgccgctaaa tgacgtctct gacgccattc cgcaacgttt gcccggtgac ctacagtcgg
     8581 ttcttgttgg agagttttat gaaaaaagtt caattcagga ttgaagaaag tcaacatgat
     8641 gatctactag attgtcttaa aacactttat ccagatgaac cgggtttaac cgtggcaaaa
     8701 ggaatgaagc tgtttgccag tgctttactg aaaagcaagg ttaaaaatga agatgttaac
     8761 gtgtcaaaag ataattatga ttttatcaaa accacaatgt atttgacagg gaaacaaaga
     8821 actttaatag agaaagcggc tcatcgtcat ggctggaatt tatccagaga atgtcgttac
     8881 cgaatccaga ctacactcga aaatgagctt gatttctttg accaagaact tttggtgatg
     8941 aatcgttgcc gtaatgcaat cgataaaata gggcgcaact ttcattatat tatcgttaat
     9001 gataatgcta gggtacttga taaagatggg ttctatcagg acgctgagcg gttgagtaca
     9061 gagataatga gtctcaaaag tgagtttgaa aactacatta tgttatgcaa agggcgaact
     9121 gtttctaaca aggttgaggt gtaatcatgg gcgtttatgt tgacaaggaa ttcagggtta
     9181 agcgtaagtc ctctgaggct ggccgcaagt ctgctttcgc ccataaagtt aaaaatggtg
     9241 ggaagaacta tcaacgcaac gttcaggaac gtatcaaccg caagggtgcc agtaaggagg
     9301 ttgttgtcaa aatctcagga ggtgcgatta cccggcaggg agttcgaaac agtattgact
     9361 atatgagccg ggagtcagag ctaccagtga tgagtgaaag cggtcaggta tggaaaggtg
     9421 acgagattca ggaggctaaa gagcacatga tagatcgtgc taatgaccct caaaatgttt
     9481 tcgatgataa aggtaaggaa aataaaaaag taacccaaaa tattgttttt tcaccgcctg
     9541 tatcagcaaa ggtaaaacct gaagatctgc ttgaatctgt caggaaaacg atgcacaaga
     9601 agtacccaaa tcatcgtttt gtgcttggct atcataacga caaaaaagaa catccacacg
     9661 tacatgtcgt ttttcgcatt cgtgataatg acggtaaacg agctgatatc aggaaaaaag
     9721 atttacggga aattcgtaca ggtttttgtg aagagctgaa gctgaagggc tatgacgtta
     9781 aagccactca taagcagcag catggactta accaatctat taaagatgct cacaaaacag
     9841 cgccaaaacg acagaagggc gtttatgagg ttattgatgt tggctacgac cattatcaga
     9901 acgataaaac caaaccaaag cagcatttca taaagcttaa gacactgaac aagggcgtgg
     9961 agaaaacata ttggggggct gattttggtg agttaaccac tcgcgagaac gttaagaaag
    10021 gtgatctcgt taagctgaaa aagttagggc aaaaggaggt aaaaatccct gcacttgata
    10081 agaacggtat acagtatggc tggaaaactg cacacaggaa tgaatggcag ttagagaacc
    10141 tgggggttaa aggcatagac agaaccactt catccagtaa agagctggtg ctgaacagtg
    10201 cggagatgat taagaaacag cagctccaga tgagaaattt ctcgcaaata aaacaggcga
    10261 tgattcaaag cgaacagaaa gtgaaaattg gtattcgctt aggataattc atgctctccg
    10321 gtaacttatt gattaagatc gatttattta tcttgttagc agaggttttg taaaaagtaa
    10381 ctagcggtaa aaaatttagt taacttgact ataaaatcag cgcaaggcga tcaatcgatc
    10441 tgcttttttg ttatcaaata gcatataaaa ctatatatca caaaataacc agcacaaaca
    10501 aaatgaaata tgtcgtaaat gcgatctaaa gatctgcctg tgtggttgaa cgcagcacat
    10561 gtagctgata gagtttttat gagatgtaaa tttgtccttt tgtttttttt ctcttcttcg
    10621 gggtcatccg agtcgagaga gcgcctgaaa ggaaaaaact atggaatggt atgttttgca
    10681 attcaccact acgaggtttg cagcagtttt tgctcatctc gaacgcctga acttctctta
    10741 cttctgtcct atggagactg aaaggtatcg tcgcccggat aagataattt catatcgaga
    10801 aagacgtttg ccgctttttc ccggttatct ttttatccag gcagattttg aagaggttca
    10861 ttccactaca ataactgcta tcccttacgt acaacgcttt atctcatttg gcggtgagcc
    10921 tttacctgta ccagaagatg tgatggcgga gcttttgtac agacaatcgc atacaacagc
    10981 tcaggcaaat cttttaagga aatcaattcc acacgaattt gctgaaattc tactcatgga
    11041 taatccgcag caaagaagta tggctttcat ccactacatc acagagagaa gcttaaccca
    11101 caaaatgaaa cggaagaaaa atgactgcta cccgaaaaaa aaccgcaacg agacgcaagc
    11161 cccaacgtaa tacactctac ctgccctcag cttctcgtga ggaactggat aaaattgctc
    11221 tggagattgg ctatcgcagg gggcggcgta tttcaagctc tggtgttgtc cagtacctca
    11281 taaaaaaata ttccagccag gctattgagg agctgataaa cgaagacgat gacgacttcg
    11341 atgactaacc attcagtcta aactttccgc gctgttctgg ccgggagaaa atcatgttat
    11401 ctactactgc ttttgcggcg cttgctttgc aatgcgcggc cagcgttcat cccgatactg
    11461 cgcatgaagt tgcaagggtt gaatctggtt ttaacccata tgctattgcc gagataatac
    11521 cgaaggttga acgtaagccc ggtgacaaag gcgtagtgtc ctactttccc aaaactaagg
    11581 aggctgcact ccagatcgta aatcaaattg aatcacgaaa tcatcgttac tcagtcggtc
    11641 ttatgcaaat aacgagtacg aattttgcaa acttcaatac aaccgctgag aaaatgtttg
    11701 acccctgcga aaacctcaag gtttcagagc aaattttggt ggattgttat aaacgtggtg
    11761 gcgacatttt acgtggtctg agttgctatt attccggcaa tccagaaacg ggaactaaac
    11821 ctgaatcaga ttttaataac accagttata tacagcgcat agggtttaat ccgcctgata
    11881 acaaaaaaaa ctgggtggtt ccttcagtta aatatgcaat cagaaaggag aatgtaaagc
    11941 agagtatcaa acctaaagaa gttaccgtat atccccaata tgccatgcgt ggcactgttt
    12001 tagatgaaaa ggaaacaaac gatgttaaaa ctcaataaac gttatttaac tctttctgta
    12061 tttatggctg cattgatgct ttgtgtagca gaacccgcct ttgctgatga tgtatccact
    12121 aaaacaactg gcttcttgca gaagattatc gattttctga ccgatattcg taagccagca
    12181 atcaccatca ttgcgctggt aattggctat atcgctatct tctcacgcca gcatgcttcc
    12241 tggatttatc cattagctat cgggatcatc atctttatca tcgcgccata tctcccggac
    12301 tggttgtcgt aatttgaaat aaaagggggc gtaaaaatga gtaccgtttt taaagggctg
    12361 acacgccccg ctttgattag ggggctgggc gttccgctct acccctttct tggaatgtgc
    12421 gttatctgcg ttctgcttgg tgtctggatt catgaggcta tgtatgccct catcctccct
    12481 ggctggtatg ccatcaagcg agttacgaag atagatgaac gcttttttga cctgctttat
    12541 ctgcgaatgc aaatcaaagg taatcctctg gcaaacaagc gcttcaatgc cgtccattat
    12601 gcggggagtt cgtacgacgc agtcgatata tcgaaagtgg acaattttat gaagcttaaa
    12661 gaccagtctt ctcttgaaga gttaatcccg tattcatcac acatcactga taacctcatt
    12721 gttaccagaa accatgatct actggcgacc tggcagattg acggagctta ttttgaatgt
    12781 gtagatgaag cggatctagc cttgcttact gaccaactca atacgctgat acgtagtttt
    12841 gatgggaaac ccgttacctt ttatacgcat cgtattcggg ttagaaaaga agtgcgacct
    12901 gtatttgaca gcaagatccc attcgtcaac agagtgatga acgattatta cgaatcgctt
    12961 tcggcggctg agtattttga aaacaaacta tacttaaccg tatgctataa accgttcagc
    13021 gctgaagata aagtgacgca ttttctttca aggaaaaagg gtaataaaaa tatcttcgaa
    13081 gaacccatta atgatatgaa tgaaatatgt ggcagattga gcacctatct ctcccggttt
    13141 cattcccgtc gtcttgggtt atatgaagaa aataacatag tttattcaga acagcttacg
    13201 ctgttccaga aactgctatc cgggcgctgg cagaaagtca gagtcaccaa tagtccgttt
    13261 tatacatacc tgggtggtaa agacctgttc tttggtaacg atgctggaca aatcactgcc
    13321 tctgaccatg cccggtactt tcgttgcatc gagatcaagg actactttca ggaaacggat
    13381 gccggaattt ttgatgcact gatgtatctc ccggttgagt atgtccagac ttcctctttt
    13441 actccgatag acaagcagtc tgcaatcaag gcgctggatg atcagatcga caaactcgaa
    13501 atgactgatg atgccgctaa atccttgctc gctgatttga aagttgctct cgatatggtc
    13561 tccagcggct atatttcttt cgggaaaagt caccagacac tgattgttta cgcagattcg
    13621 ccggagcgtc tggtgaagga caccaatatt gtaacgacga ccctggagga tttagggctg
    13681 atcgtaacct attcaacctt gagtcttggc gcagcgtatt ttgctcagtt acctggtaac
    13741 tacacgttac ggccacgcct gagttctatc agcagtctga actttgccga aatggaaagc
    13801 ttccataatt tctttacggg caaggagaaa ggaaatactt ggggtaacaa ccttatcacc
    13861 ctgggcggct caggaaatga tatttataac ctgaactatc acatgactac cgagcatcaa
    13921 aattacttcg gtaaaaaccc cacgctgggg cataccgaaa ttcttggtac gtcaaacgtg
    13981 ggtaaaacgg tagtgatgat gactaaggct ttcgccgccc agcagttcgg aacgccggag
    14041 tcttttccac ctgagaggaa attaaagaag ttaactacag tatttttcga caaagatcgg
    14101 gcagcggaac ccggtatacg ttcaatggga ggtgcttact ttcgggtgaa agaaggagag
    14161 ccgactggct ggaaccctgc ggctttgcca ccaaccaaac gaaatatttc ctttatgaaa
    14221 gacctggtga ggctactttg tacgcttaac agtgagccgc ttgatgatta ccagaaccgc
    14281 ctgatttctg atgccgttga gcgcctgatg cagaggtcaa accgctctta tccgatcagt
    14341 aagttgcgac cactcattct ggagcctgat gatactgaaa cccggcggca tgggcttaaa
    14401 gcacgcctga atgcctgggt gcagggaggg gaatttggct gggtgtttga taacccggac
    14461 gatacatttg atgtggacaa cctggacgtt ttcggtatag acggaacgga gtttctggat
    14521 aacaaagtgc tttccagcgc cgcttcattc tatctcatct accgtgtcac catgctggcc
    14581 gatggccgcc gactccttat ctacatggat gagttctggc aatggattaa caacgaagcg
    14641 ttcagagatt ttgtttataa caaactcaaa accgcgcgta agctggatat ggtgcttgtc
    14701 gtagcgacac aatcgccgga tgaactaatt aaatcaccta tcgcggctgc cgttcgtgag
    14761 cagtgcgcaa cacatattta tctggcgaac cccaaagcga aacgtagtga gtacgtagac
    14821 gagctggaag tgagagaact ttattttgac aaaattaaag ccattgaccc gttatctcgt
    14881 cagttcctgg tcgtcaaaaa cccacagagg aagggggaaa gtgatgattt tgcggctttc
    14941 gcaagactgg atttgggaaa agcggcgtat tacctaccgg ttctcagcgc atcgaaaccc
    15001 cagcttgaac tgttcgatgg aatctggaaa gagggtatga agccggaaga gtggcttgat
    15061 acctatctgg aacgtgcaaa cctgatttaa ggaatcccta tgaaaaagca tatcgttgcg
    15121 gcacttatcg cctctgttac ggttatttct ggtgctcagg ctggtgttcc cgttgccatt
    15181 gatgcaaacc ctgaatgggc tgtcgaagcg cagcgctgga cagaacgcct caaacagtgg
    15241 caggacaccg tgaaccacta ccagaaacag attaatgcct ataagcagga gctgctgact
    15301 aaaacgggca ttcgtgatgt tcagggactg gtgcagtctg cgcaatctgt cagtaaggag
    15361 ctggagaata tttacgacca ggggaactcc ttcattgatg attacattaa gaacccggaa
    15421 gccaccctgt ctgagcaagc cagatcacta ctggccgatt ataaggtgac aaacacctgt
    15481 aaggggctgg gatatacggg cgacctggtg cggggctgtg aagcctcgtt cctgtcccaa
    15541 ctggcgggga tcgagtacgg caataagctg gaaagtaaac tgcgtgaaga taatcaggag
    15601 atggccgacc ttatcgacca ggtgaagaac gcccaggaca cgaaagccac gcaggacgcg
    15661 acaaacgctg tatctctggc aagcctgaaa tttaacaagc tcaaatttca gtatgaaatg
    15721 tatcgcgata agcagcgcga tcttgcagaa tacaaggaga aaatgttaca ggctgctttc
    15781 caggagaaac aattaggggc tgttaataaa gaaactccag ttgttgatta taaggcagca
    15841 tttgagcagc agagttatga aatgaactga gggggcattt tgaaaaaata tggattagtt
    15901 gcggcgttgg ggcttacatt ctttcttacc gggtgtgaag aggttaaatc tgtagactgg
    15961 tggcagtctc acgtagacga tgcaacgaaa aaagtagctg aatgcaaaaa gtctgggagt
    16021 gatagcgaaa attgtaaaaa cgctaaggaa ggtttgttta ggtataagca attacatcct
    16081 aagcatgttg actataaaga tgcattcaaa aatgtattgg gtaaagatgg aagttaaaag
    16141 gagccactat ggcaacttct aggtatttcc aagccgctca tgacgttatt gttaaaactc
    16201 ttgaccagtc tttgactggt cagttagata atttttcttc aatagcgtct cagttgggta
    16261 agtatggtat ttccatttat atattgtggt atgcctatac cacaatagtt gggaagcaaa
    16321 aaaccgcagt gcaggatttt ttatggaatc tatgtcgatt ctggttaatt cttgtttttg
    16381 tcaaaaatat gggggggtgg ttagatagtg caactcaggc cattgatggg ctgaaggaaa
    16441 catttgcagg aggtgatcct tggaaatggg ttgacgagct ttgggagaaa attcagcagg
    16501 tagctgcata tcttatgtcc aaagatactt cgaagtatgt gaaaacagat ggggcaatcg
    16561 catctttatt aacatatgct ggaggaataa ttgcattatt gctaacttca atagtttatc
    16621 tcgccgccga agttactatt aagatactta ctattaccgc gccgttgttt attatttgtc
    16681 tttcatttgg ttttttaagg cagatgttta acagctggct tcagttaata tttagctcat
    16741 gcttcatatt cttgttttgt ggactggcaa ttaaagcggg aatgaccttc cttaatggca
    16801 ttctgactat ctcgatagct aacgcagatg aattaaatct gatatcaaca ggtgctcagg
    16861 ccggggttgc aggtgcattt atggcctgga ttatctggca agccaaaacc tatgcttccc
    16921 agctcgcagg ggtaggtgta gaaggcgcga tgcaaggggc agccgctatg gggattggtg
    16981 ctggcgtgtt cggcgcttcc cgtatggggc gcaatctgct tggtatgggt aaaaatgcag
    17041 ggattggcgc atggaaaggc gttcgccgtc aggatggagg gttcaaccag tctcctggtg
    17101 tatccggtaa gttggggaat ctgaccgggc agggcgttaa tattggcgct aagaggcttc
    17161 gccaggctgc gatagatgcg gcgaaaaaga aatatggagg ttaaccgatt tattatttaa
    17221 atctgtcaac tctgagtgtt ccgcagtaaa tattcactcc tctatttagg ttctcacatt
    17281 atgaaacttc ttatcacagc tatcgtgacg ctttgccttg tcggatgcca ggcgtcacat
    17341 aaacaacctc cggtatccgg aaaaagcgaa cctgttaatt cagcagaggt aatgcgcaat
    17401 ggggtttaaa ctctcagaat taaaacttcc cggttttaac aagaaaaaag aagtaacgga
    17461 ctcttcaact acttttgaag agaaaaatgt attgatgcag gagaaaatga accgcattta
    17521 taaattcggt ggtattgcag ggatggccgt aggtgtgttg tctctgctgg cactgaatgg
    17581 agcgctaccg ttaaagagta cggttgtcga agcttatctt attaatggtg tcactggcgt
    17641 tgctgaaaga ctgacttctg ttaaaaaaga aaacctctct gaaaatgaag cgctggcgaa
    17701 atacttcatt actcagtatg tgaagcgtcg tgaagggtat aactatttca gtctccagca
    17761 tgattatgat tatgttctgt tatacagcgc tgagaatgtg gcgacggatt acaacgcttt
    17821 aatcaacggc aaccagtcac caaaggttat ttataataaa gcggaaaaaa ccgcatctgt
    17881 tcaggataat ccgtccgtga ttatcagtcc gtcatcccgg cgcgatgata aggatatggg
    17941 agcatatatc cggtttaaat taaccattcg aaatgtcgcg acaggccagg atgattatga
    18001 atactggaac gtccggttga cctaccgtat tgaaccacag gtcgaaatgg catcgggtga
    18061 ccgaaacaat aacccgctta aattcgttgt aacgagctat gtacgcgata aagaagtgaa
    18121 agggtgaaaa ctatgaaaat gaataaagga gcgctaattg tggcgcttct gttggtgtcg
    18181 cacgtctgcc atgcagccgt tacgccagca gccagccgtt ttgatccccg taatcagatt
    18241 gtcagttata acccgcaaaa cacgacagtc ataaacagtg cggttggcta tacaaccaca
    18301 ctggtatttg acgaggatga aacggtcatc agtgccagaa ccggctttcc ccagggctgg
    18361 gaagtgaaca aagaagataa cctggtgtat ctcgaagtga agcccgtcaa acagaccgta
    18421 cagaagaaca gtaccgatga caatggcaac cagtcttcag aggtggtcag tgtagccctt
    18481 gatcctgaaa acgacctgga acgctggcga acaaacctgt ttgttcgcac aacaaaacgt
    18541 aattacagca tggagctgaa cgcccgaacg ttccggcagc cggataagat cgcgtttgtt
    18601 gttaattacc agtacccgca ggaacgccgt aaggagcaag ccgaaatcga gaagaaacgg
    18661 attgaggctc ttaacaagcg gcaggaggag caggcaatca accgttctct tgaaaatgcg
    18721 aagtcgcccc ggaactggga ttactggaag cgggtagctg acggcagcca gtcaatcagc
    18781 cctgattatg cgtatgacga tggtcgctat acctggtttg gcttcagctc cctgaagaaa
    18841 atccccagca tttttgtgtt gagcggcgaa caggaaacgc tgactaaccc ggtagtcaaa
    18901 aacagcggca gtttcaccgt tgttggtgtt cctgtagacc agcgctttgt tttgcgtatg
    18961 ggaaatcagg ttgttggggt tgaaaaccgg ggctttggca aagtccgtct tccggcagga
    19021 gataccgttt ccccgaatgt tgagaaagag gtgatccagt gagcgaacag gaaaataaaa
    19081 tcccgaccgc tgtagaaatt gaacaggcac tacgggaacg gcatcagaaa gaaattgagc
    19141 aaagtgacaa aacggataag gaagatgaag atgacggtaa atcagtaaaa cgcctgggta
    19201 tcgagaagct taaaaaatcg cgtaaggggc tggtgattat tgtggccgct ttccttctgc
    19261 tggccgccgg ggtgtctgtc tactatatcc cgtcgattat tcgtgcaacg tccagcggtg
    19321 atgaaaagcc tgccagtaat gcggtatcta ctggttcagt aaaacgcgcg acaggcctca
    19381 gcgatgatgt tgatccattc aacaccaggg cagaaccggc taagacggaa gaacggaagg
    19441 aaagcagcga caaagcggaa acgccaccgg aaaaagtaca acaaaacttc agtcgtgcgc
    19501 tggatgtggc ctatgggggg agcagctctg cttcctcaaa ttccggtggt agctcgtcaa
    19561 cggccagcaa taccaggaac gagggggacg gcagtgacaa acaggcagag gttcagcctg
    19621 ttaatgcagg gcaacccgcg cagctttcta aaattacgcg cgttccttat gaccctaacc
    19681 ttttcattcc tgaaaatacc gcgattaagt gctcgctgga cagacgattt atttcggatc
    19741 tggctggcaa gctggtctgt acgattaatg aggacatata cagtgcaaac aggaatgtaa
    19801 agctaattga aaagggaaca gccgcatatc tgatgtataa aacgggcacg ttcaatcatg
    19861 gtcagggagc cgtgtttatc gctgctacga agcttagaac acgtaaggaa cctttcattg
    19921 atattccgct gattgataca caagcggcgg gagcgctggg tgaggccggg gcttcaggct
    19981 ggattgacac acattttgca gatcgcttta tgggcgcgat gatggttggc atgatccccg
    20041 atgtggcaca ggccgcaagc ggagcggcta aaagtaataa agacaatcag accgactata
    20101 cagctaacag tcgccaggct tttgctgata tagcacgcga agcgtttgca aacagcgtaa
    20161 atatccctcc aacgctttat aaaaaccagg gggaaatcat tactctgatc gttggtcagg
    20221 atttggattt ctcttctatt tataaactga aaatgaaata aaggcgggtg cgatgttgaa
    20281 agaaaatatc catttggctt atgaactcgt aaatgactac tttcataaac cacttaatga
    20341 aattgaaggg ctgacagaaa tcgccgttaa cagaccaaat gagcttttta taaaggtcag
    20401 aggtaaatgg cagcagcatg aattaaaaat ggattttctt gattgtatgt catttgcagg
    20461 ggcaatttct gattatcatg atggtgggtc ggttacacca gaatatccct tacgttctgt
    20521 tacgctcccc ggaggggagc gtgtacaaat agtaattccc ccggcaacgg aacgggaaac
    20581 ggtgtctatt acaatacgta agccgtccag tgtgtttatc gaccatgata cctttgttaa
    20641 acagggtttt tactcaaggc taaatcaggg ggttgaattc agggataaag aagatgaatt
    20701 atctttaatg tttaaagata attgttttga acgatttgtc cctgaatgtc tggttaaggg
    20761 taaaacgatg gtattttgtg ccggaacggg ggcgggtaaa accacctttg caaatgcctg
    20821 tcttcagtac attccccatc atttacgatg tatttcaatt gaagatacag atgaagcaaa
    20881 gttcaggttt cacaaaaatc atgtgaaatt gtattacccg tcagaagggg aaagtagcac
    20941 tgtcagctcc gcttctcttt tacgttctgg ttttcgtatg aacccggaca gaatcctcat
    21001 gactgaggtt cgcggcgcgg aagcctggga ttttctcaaa ggctcaagtt ccggccatgc
    21061 agggaacctt acaaccgtcc atgagagcac ccctgaagat gctgtgcttg gacttgttca
    21121 acggtgctat atgaaccctg aatgtcagaa tttgccctat aacattatat tgcggagggt
    21181 gttaagcaac gtcgatgtga ttatgagtat taaatacatc gatgaggaag ataaccgatt
    21241 tgcatcgggt atttactatc gtgatattca ttttcaggaa tactttgaaa agctgaagga
    21301 gtgattatgt ctctaaaact acccgataaa ggccagtggg cttttatcgg tctggttatg
    21361 tgtcttgtga cgtattatac tggctcagtt gctgtttact tcctgaacgg aaaaacgccg
    21421 ctttatatat ggaagaattt tgattccatg ctgctgtggc ggataataac agagagtaat
    21481 atacggacag atatcagatt aactgctatc ccctctcttt tatcaggtat ggtttcgtct
    21541 ctcattgtgc ctgtttttat aatctggcaa ctgaataaag cggatgtagc tctttatggt
    21601 gacgcgaagt ttgccagtga taatgattta agaaaatcga aacttctgaa atgggagaaa
    21661 gaaaacgatt ctgatattct ggtcggggca tataaaggta aatacctgtg gtataccgca
    21721 ccagattttg tatcacttgg cgcaggaacc cgcgcaggta aaggggctgc aatcggtatt
    21781 ccaaacctgc tggtcaggaa acattcactg attgcattag atccaaaaca ggaactgtgg
    21841 aaaatcacca gtaaggtacg cgaaaaactg ctgggtaata aagtttttct tcttgaccct
    21901 ttcaacagca aaacgcatca gtttaacccg cttttctata ttgatttaaa agcagagagc
    21961 ggtgctaaag acctgttgaa gttgattgag atcctgttcc cgtcttacgg tctgaccgga
    22021 gcggaagcac actttaataa cctcgcgggg caatactgga cggggctggc aaaactgctt
    22081 catttcttta ttaactacga cccctcctgg cttggtgagt tcgggcttaa acctgttttc
    22141 tcaattggtt ctgtagtcga tttgtacagc aacattgacc gggaactgat actcagtaag
    22201 cgagaagacc tggaggcaac aaaaggactt gatgaaaacg cactgtatca tctgcgagat
    22261 gcgctgacca aaatcaggga gtatcacgaa accgaggatg agcagcgttc gagcattgat
    22321 ggttcgttcc gtaagaaaat gagtttgttt tatcttccga ctgtccgaaa atgtacagac
    22381 ggcaatgatt tcgaccttcg ccagttgcgc cgggaagata tcactgttta tgttggcgtt
    22441 aatgctgaag atatgtccct ggcctatgac ttcctcaacc tgttttttaa cttcgttgtg
    22501 gaagtcacgt tacgtgaaaa ccctgacttt gacccgaccc tgaaacatga ctgtctgatg
    22561 tttctggatg agtttccgtc tattggttac atgccaatca ttaaaaaagg gtcaggttat
    22621 attgccgggt ttaaactcaa acttctgacg atttaccaga atatcagtca gcttaatgaa
    22681 atctatggtg ttgaaggtgc caaaacgctg atgagtgcgc atccctgccg gattatatac
    22741 gctgtcagtg aagaagatga tgctaaaaag atttcggaaa agctgggcta tatcaccacc
    22801 aaatcgacag gctcaagtaa gacaagcgga cgctcgacgt cgaaaagcag ttcagaaagt
    22861 gaggcgcagc gcgcccttgt gctcccgcag gagctgggaa cgctggattt taaagaagaa
    22921 tttatcattc ttaaaggtga aaacccggtt aaagctgaga aagccctcta cttcctcgac
    22981 ccgtatttta tggacaggct gatgatggta agccctaaac ttaccgagtt aaccgcctct
    23041 ctgaataaga ctaaaaaagt attgggtgtt aaagggctta aatatccttc taaagaaaaa
    23101 atgctctccg tcggtgagct ggagtcagag gttttactat gaaaaaaatg ctaatggtcg
    23161 gtgtcctttt tctctctgcc tgttcctctc cgccggaacc gccacaggtt gactgggaac
    23221 agaaacctga aacggtgaat acacaattaa tggactggca accgacatat tcaatcatta
    23281 aatcagacaa ggttgattca tcgtgggtta aagttatcca tgatttcaga cctgaaaacc
    23341 gtctctacga tgatgctgtt ttttactctg ttgcacattc tgattcagtg attgttgaaa
    23401 ccagtaacgg aacagacttt ttcacagcta aaaactggtt gagggcgaac ggtgctaacg
    23461 gtgtcataca gtatcgctat aaaatgaact gtctttcttg ccggactacc agtatttatt
    23521 tatcacgata accccggatt aataaaattc ttgtaatttt attgagccgg ggttgaacaa
    23581 ccgcagggcg ttagttgccc gttatccatg aggtgtatat gaaaaagacc gtaaccacgg
    23641 cagtgctgct ttgtgcgttc gctgccggag ctgctcatgc tgaggaaaag gccgacccga
    23701 acgatccatg tgcaatggtg ttatgccttg ccggaaagct tgacggcagt agtccggcag
    23761 agtgtgaccc gatgtataaa agttttatgt caatcaggaa aaagaataaa catggttttt
    23821 tacccaatca cacggcagat gccagaaaga aaaaactaaa tgaatgtcct gcggctgatg
    23881 caggtacagt aaataaaatt atttcaagct ttggtcgatt gaaaagcttt taagtctgtt
    23941 atggtttaat tctgatgtga aaacgcaagt ttcaggtttg agactggaac ttgcgaacat
    24001 tttttacagg ggggaaggat gaaagttatt aatgcacctg atgcaagaag tgtaagagtc
    24061 gccggaattg aaattatcga tagtgtcaaa gcggtcgctt ctgtttttac tgaaatcttg
    24121 ttgtttatgg tctggtttcc ggcaattatc tatggtcttt atcgagtcat catcgttttg
    24181 tgggatgatt ccttaaaacc gcaatcactc atggagttta ttaatttcat ggttgagtta
    24241 tacagctatg tgcttccttc gctggcagtt atcgctgtgg ttttaatcgt tattttaagt
    24301 tcatttaaag tgttttctaa ggtctggaga aaatcatgtt aagagaatta agtggtgtga
    24361 gccgtacttt atggcgagct gcatttttta gcctggttaa ggctccagca atggcgttgt
    24421 ttattggctt tgtctttctg tctttcaata actccattgc ggacacgttc ctgacctcag
    24481 caagagaact taccgggaat gctccaccgg ataaggttca gacctgtgtc tttaaaaaaa
    24541 gcaaacagga actatcacct tacgtacaga aagaaccatg cgtaaatacg ctgactgatg
    24601 cgaaggactg gtctcagtcg ttcgacagaa gcattcgtcg tatttactgg actatagccc
    24661 tgttgggttt ttttacctgg ttttgttttg atggtatggc tgctcagttg atgctgaaaa
    24721 ttgatgacat ttgggagaga aggaaaaaat gaagtacttc ctttatgcct tttctcttgt
    24781 tgttgtcata ttaccacctg cgttgttcgc ggctcagatt cagggaaaag ttattcgtgt
    24841 gcttgatggt gacaccattg aagtattgca ggagcaacaa cctgtcaggg ttcgtctcct
    24901 gaatatcgat gccccggaaa agaaacaacc ctttggacgc tggtcaacca atcaacttaa
    24961 agccctgctc gcagggcaat ccgttaccgt ctcttatacg caaacagatc gctacgggcg
    25021 agtcctggga cgagtggtga cagcgaacgg cactgaggct aaccgccagc aagtgctaaa
    25081 aggggctgca tgggtttatg acaggtacaa caccgataac tcattaccgg ctctgcaacg
    25141 ggaagcacag acacagaagc gcggcctgtg ggctgataat caacctgttc ccccgtggga
    25201 atggcggcac aaaaacaact gacgcgcttc gcttgtccaa cccctccaca tcctgaaata
    25261 aatgtcaggc tgtgtcacgg ttaacgtgaa aaggaataaa tcaatgatga cagaatctga
    25321 taaagaacgt ttcaataagc gtatatgtgt tggtcatgtg cttgtcagtg ctgacattta
    25381 tgtaacacct gttatgactg aaagcgcggc cgaggtggag ttaactgtcc ctaacgaaga
    25441 ttataaaaag gcaatggatc tgtatgagcg tatttgccag tttgcattgc ttcatggtga
    25501 agatttacaa ggactattcc agactagcag atattactac atgtcatgtt tcgtgcgtga
    25561 tattgaagca tttaagaaag aattcgaaaa agaggaagag ctaaagcctt tatttaatca
    25621 tgataagggc gatacggctg agtttcttat cagcttcccc gagaaggcta actatgatga
    25681 taaggaacca gttaaaaact cctttctgga aatcacacaa aaacatgtcg attcattaga
    25741 tgaacttaca tggggtgatt ttgaacacag agcattcact ggcggaacgg taggttttgg
    25801 catcaacccc aatacaatgg aacgcattaa ttttgatgat gagcgtgaca aaataacaaa
    25861 actatctcgt aaggatttcg tggcgtctaa tcttactgat tctttcgaag atgattttta
    25921 tgttaatcct ttatttgaag gtgcacaaaa aatcggtgag attgataatc acccggtata
    25981 tttcaactca agggggtttt acttctactg gaacaaagaa actgaatacc tgctggaaag
    26041 ttggttgact ttcccgtcgt atccctatgg ctggtaaagg agagtatatg tacctgcata
    26101 ttgttccacg attgtttcat ctgatggcaa ataaatgcca tcttgaatca gttactattc
    26161 ctgaactgga tttcaaaatt gaagtggatg cactgtcaac gggcagacca cacccaaata
    26221 aaaatatctg ggttgggatg aggaaaggcc gaaaggctat caacggactt ttactgaaaa
    26281 cagataaaca cctcaagtgg tttaccgctg actaccaatg gcatatagaa aatatggggc
    26341 taattactca tcgtgtgaca acctatattg aagataatga gtttgacatg gtttcacagg
    26401 atatcatgtt aaatggtggt tttgagcaat gggagaacag acgacattca gcttatgatg
    26461 aaatttctcc tgcaaaaaat cagcctcgaa tggaatcttt tttatcgaat cccggtaaaa
    26521 gagattcgca tgatacatgg cgggtatttg attgggggga ttttctcgaa ctcagagaag
    26581 aaagtttact cctgcatacc attcagtccg aacgactgaa cacagatttt cctttgttca
    26641 accgactacc ctcactggaa caagccatta ttatctgagg tgattgttat ggattttagt
    26701 aaatttgatt tcaatcatga ttgttatgtt gacttacatg ttggtgatta cggctcattg
    26761 tctggcttgt tttttacagg taaatcagac ctggctatta ttgaaaagct ttttaccgat
    26821 tctcacgact ggcaaaactc ttttcagcgt gaaggtagac agtatgtgat ggggtttgtt
    26881 gatccgggta atgtgcaatt cattgcgttt atgcagcatg catttacaaa agaaaaagaa
    26941 cacgacgaaa gattttatcg tgagaatggt tattatgaac agtcgcatga cttctttaat
    27001 atatggtttg ataacgatgt tagcgatgtg caaatcagtt ttccgctttt aaaggcagta
    27061 gataaagcgt cagaattaat ttaaggatta cttatgagac tttttattgc agaaaaaccc
    27121 tctttagcaa aagccatttt tgaagggctg ggtggtaacc caaatacgga aaagaaaaac
    27181 ggctattttg aacacggttc tgatgttgtt acctggtgtt atggtcatat gctggaactt
    27241 tacgacccgc aggattacga cgaaaagtat tcaaactggc gtttcagtga tttacccatt
    27301 aaagcggttt atcctccaaa atataaaatc aagccagaat ctgaagcaca gacccgcatc
    27361 attctgtctc ttatcgataa agccgacagc atcgttcatt ctggcgaccc cgatgatgaa
    27421 ggatgtttgc tggtagatga gattttaggt tatgccggaa acaacaaacc cgtccagcgg
    27481 ctgcttgttg ccgacctcaa ccttgcgcca gtgcaaaaat cgctggcgaa tttacagcct
    27541 aacgataaat ttcgcggtat gacgttaagc gccctggcgc gttccctgtg cgatcagggt
    27601 tttggctata acatgacgcg gggatgtaca ttaaaaggcc gtgagaaggg ctatgacggc
    27661 gttctgaacg ttggccgggt acaaagtgcc gttcttggtc tggtgaacat gcgcacgctg
    27721 gcgaaccaga accacacaga aagtttttat tacgatgtat tcgccagtct gtcgatgaac
    27781 gggcatcaga ttaaggcgaa atatcagaca acagacgacg atcagataga cgagaaaaaa
    27841 cgcctgattt ccgaagctca ggccgagcat attgccgggc gggttacggg taaggacgct
    27901 attgttacta tcgcgacgac aaagccggaa aataccaaac ctccgctgcc gcttaacctt
    27961 tccacgcttc agcagctatg cgcaaagcgg tttggttatt ctgcaaaaga tacgctcgat
    28021 gtgatgcagg ggctgtatga aactcacaag cttctgacct atccacgttc tgacaatcgc
    28081 tatctttcag atgagcatta ttaccaggcc ggagagattg ctgccgcgat agcggccacc
    28141 gtacccgaac tggcgtctgc gatcgtagat atggataaag gccagaagca caaagccttt
    28201 aatgccagta agattgaggc gcaccacgcc atcataccga cgacaaaaag cggagccggt
    28261 attcagctta atgaaaaaga gcggaacgtt tataacctgg tgtccgtcta ctttatcggg
    28321 ctgttctacc cggatgcgat ccgcaacaag acgaaaatcc actttgatat taagggggat
    28381 acctttacgg ccacacagag cgttctggta caaaagggct gggaagcgct gggtaaggat
    28441 aatgatgatg aggaagaaac tgaagatgcc ggaacggacg gttttgacct ttcatcgctg
    28501 aaatttaatg acagcggcct gtgtgaatcg gcagacgtgg acaagaaaaa gactacacca
    28561 cctcgctatt tcacagagtc aacgttactg gccgccatga cgagtgcggc aaaattcatt
    28621 gatgatccgg ctctcagaaa ggcgctggaa gcgaaagacg agggcagcag tgatcgtggc
    28681 agtatcggaa cggaagccac ccgtgcgggc attcttgaga aactggcggc aaataccggg
    28741 cttatctcca tcgaaaaaga aaaggggtat tcggagctgg tatggaaaac cacaaaacaa
    28801 ggccaggagt tttgcgctgc actgcctcct gaaatcacta aaccggatat ctccgctctg
    28861 tgggctgaaa agcagtctca gatcaaagcc ggagagctga cggttgagga gtttattaag
    28921 gaaaatgatg aatatgtcca gggggtaatc gacgagctgg acaggaacgg aatttcgatt
    28981 tcttcaaatg ccacgccctg cccggtctgt aacaacggtt tcctgcgtaa acgtaagggg
    29041 caaaatggct ttttctgggg atgctcctgc taccctgaat gcaagacaac attcccggat
    29101 aaagacggca agccggatat ggaagcaaaa tccagatcag aaggttccat gtcccggctc
    29161 gaagccccct gcccttcatg cagtaaagaa attattatcc ggcctaaagg ctttttctgt
    29221 tccgggtgtg agtttaaaat ctggtctgaa gtatcaggaa aaaaactgac gcaaaatcag
    29281 gttgagatgt taatcaaaaa aggtaaaacc ggagagatta aaggctttac cagtaataaa
    29341 accgggaaaa agtttgacgc tgcaattgtt ttgcaggata aagctacggg taaacttggg
    29401 tttcagttca gtaaaaaata aggattaact cgatgagtga aaatgaaacg tttgacgcaa
    29461 cacgaaagct actcctgaat attcgctctg tccgtgtttt tgcgcgagaa accagctttg
    29521 agcaactgct ggaaatgcag gaaaagctta acgccgtaat cgaagaacgc cgtgaagaag
    29581 cagagcgtga ggcagcagaa cgcgaagaac gcgaaagaaa gcgccaggaa ctgctccagc
    29641 tgatcgccgg agaaggcttt tcaccggaag aactgcttgg cctgaccgaa gatacaccaa
    29701 aaacacgcaa aaagaccttg ccaaaagcgc cgcctaaata tcagtttgac gaaaacggcg
    29761 aaacgaaata ctggtctggc cgtggccgga caccaaaacc aatcgacgaa gcgttaaaag
    29821 ctggccgttc tcttgatgag tttctcatca aagaagatgc ttccagctct gttggtgacg
    29881 aaaagtaatc taacaagcct ctgacactgc gtcggaggct tttttttagc aaaaagggcg
    29941 cggggggtta tggtgaagaa atctttgaat atcttcgcgg ggataaggga aatagtctct
    30001 gatatctttg gtttctaact taccagtgca gtgatacgtc tgaaaataga tccactctgc
    30061 tattgttttg tagatgtgat ttcccatgtt cgcactttga gaaccatact gcatgacttg
    30121 tgcatccggg tcgttacaca tttccggcgg agtgagtaca tgatatgtcc tgcataacag
    30181 cgggcggtaa ttgtagattg agcatgttcc cttctcagac aaaaacggac attttgactc
    30241 atgcccggtc gtaagcgggt tgtctctggc agtgagttta cttgcttgtg caatatgtgt
    30301 tgcctcaagc gcggttaaat gtacatcgat tttacagcac gaagagcacc ccttttgaca
    30361 ggaggtaaac gtgctcacaa attctttgtt aaaacgatcc aaaaaggcgt acatctgttt
    30421 taacttcagg taaatatttc ctgattgagt attgagttta ttaatgagtg cctttaactc
    30481 atcgagatac ttatcaggta cgggtttcag attggtatag ccgggtaatg tttcgcctgg
    30541 ctccaggtgg atcactgagt taggtttgat atccattgct tttgcttcct ttattcttct
    30601 cgcgctggtt gtttatttga cactaaaaca agcgttaaac aatggcaagg cgtcaaaccc
    30661 agcagtaaat caggtctgcc agcaaaccag tttcctgcag ccggtttggc cgttgatttt
    30721 tgccagcaat cttacgcgct cgatgctcgc cttgggcttg aaattgccag caaaaaagat
    30781 tgccgctagc aaaggtgtgg tttatattat ctgtatcgta cgatacagat aagaggtaag
    30841 acgatgaatt atgttgatat tgccagggta tggcgtcagc acaaccagga gcacgctgat
    30901 tcgggcgtgg ttctgatttg ggacgggaag gtgtattgct ggaaaaatat tctccgcgac
    30961 cctcagcatg agcgccccgg agtgatagcg gtagatactg aagagaatgt ttttattgct
    31021 gaaggtggca atgaatatga cggcgcgaaa tgctgggttg tctttcagga gtcctgatga
    31081 tgacgagagc cacagaacgc gcttacagcg agctacaaca ggcgtttgat ttctataacc
    31141 agcgcctttt tgatggcgaa ctcccggact gcctgattac gttccagcgc ggcaagaaca
    31201 caatgggcta tttcagttac aggcgctttg ttgctgctga cggcagcggc aggatgattg
    31261 atgaaatcgc cctcaaccct gaatacttcc cggtgtaccc gcttattgaa gtcatgcaaa
    31321 cgctggttca tgagcagtgc catatgtggc agtaccacta cggcaacccg tcgcgtaaga
    31381 cgtaccacaa tgcgcagtgg gcggccaaaa tggaaagcat cggacttatg ccctcctcta
    31441 ccgggagacc tggtggcgcg aaaatcggcc agaagattaa tgactatcca atacctggtg
    31501 gccgcttcca gcgtgtcaca ctggaactgt tccaggggca atttgctttg agctggtttg
    31561 atcgcttccc tgtccaggtt gaacaacaaa aagacatgac cgccgtcatc gagcagtggc
    31621 gagaaacgct ggctcaggca catcaaaatg ctgaatccgg gattgatatt gaagcggtgc
    31681 tatcaatggc gctgctgccg tcagtgtcac cgcagaacgg gaacggcgat tcaggtgata
    31741 tggccgggag caatgataac ggtctgcctg ttgcagcttt tgaggacaaa ccaaaaaaga
    31801 acaaagtcaa atatcagtgt cgggggtgcg gtgctgccgt gtggggcaaa gccggactta
    31861 acatagagtg cggcgattgc gagctggctt tcatcgaaaa ctaattgcca gcaaatcttc
    31921 ccgaccgcag ctgttggcca ttgatttttt gccagcaaag ttttcatccg gggcggcgcc
    31981 ggcagcgtaa aaatgacagc aaaagagggt tatcatgggg cattacacaa tcagaactaa
    32041 tgacgacgaa gatcaggcca ttaaaaaggc gcaggaagcc accggacagg catcggccag
    32101 caaaaccttt atgacggcta tccttgagct tcagcggaac agagatgaga tcgcgcagct
    32161 acggcgtgaa ctggcgcagg aacaagccaa aaacaaagag ctggttgcat cagtgaagca
    32221 attcaggaac agcatgaatg ccatgtttga actggctggc aacaataaaa gttaatatca
    32281 ttgctcttgt ccgggcactg tcgggggttc cttttacggg tgatggtttg tttatcccgg
    32341 cattgcccgg cgctctctcg taaattctcg cgcccaatcc tcctcgcaaa acctcagaat
    32401 tcacgtagcg caccgttatc accaggcgta aaaaaacccg actggtgaga tcgggttttt
    32461 atacggtttc cggttctgag ttggtggctc tgaccggagg aagtcactct acacctaacg
    32521 cctacatttt atgcactcag gcgaagtatt gcaactaact gtggttaagg caccacattt
    32581 agttgtgtat caagggtttt gtataccgta taatcatgga gttagccgtg tggtgtggct
    32641 tcttcccctg cccttcccgt ttctgcgggt atgaacgatt ttaaagtcct ggctgaacaa
    32701 acaggtggtg ctgtgttcag tgctctggca ggaggaagtc actctacacc taacaatgcg
    32761 agagagccgt tgtgacaggc agtgtatgag taagcagcgg tgatttcctc cagataatct
    32821 ggagaaacgg atggttaacc tgttaatcat cgttctgagg gcggtagcgg cgcttgcaaa
    32881 cgcgctgatt gccattctgg aactgatccg ccagttcatc gactgatgaa cacggaaacg
    32941 taattaaggc cgggggcaca ccacctccgg cctttaataa aaatacactt tagttacaac
    33001 attcactagg ctgtagtgag caccacacac ctgaccttct gcgcacatat cacctttgct
    33061 gctcactaaa ggaacactat aataattatt atgttgtaac tactcatacc acccaccgtc
    33121 atactcattc cagctcttac cagtcttctc gtttgtcaac gtcatatcat ccacgacaca
    33181 atttctcatg tcagcgaaca tattgatttc acgaaataaa tcatcaatct gttcttttag
    33241 atcctcttca ttttcatacg taaagaacag gcggtattca ttattatcca gtacctcacc
    33301 ttcaaaatcc gcttcaatca gccaggcaat ttcctccttc acttttttct tccctctggt
    33361 gaacttgcta ccattggcga ccggaaccca caaaatagcc gaaagtcgcg tttccggctc
    33421 aggagctgac ggctggcgac tcgacttaat ctgtctaacg gccttgctga ttgtcgcccg
    33481 actgcaaccg agcacttttt gaacctggct ccaggagctg ccgctcgcaa ttagcctgtt
    33541 tatggcgtca tagcgcgact gattaacctg gcggccttta tacttccctt cccttttcgc
    33601 cctggcaatc ccctgctgct gccgttcccg gcgctgttca tagtctcgcc tggcgacggc
    33661 ggccagcata tccagcaaca tatcgtttat ggccgaaaac atacggctgt caaaatcatt
    33721 gtgacccgat gctagccagg ttgtcggaac gttgacggcc acaacccgga tatctttctg
    33781 ccggatcatt ttcttcagcg tgttccagtc ctcccctacc aggcgtgaaa gcctgtccac
    33841 atcctctacc agcaagacat cgttttgctg acagtccttc aggagccgga acaactcagg
    33901 gcgttcaagc ttagaacctg actcattttc aatgtagtag ttacagatgc tcaggccgcg
    33961 ctcgatggcg aaggtattta tcgtgtccag ggcgcgtgtt gcatcctgtt cagtcgtgga
    34021 tgcgcgtaag taagccctga caaagccttt cggtactgtt tgagtcatta ttgggaacca
    34081 gttcattttg agttaaccag gcacacccat acagtacccg tttccgttgg ttcagggaag
    34141 gcacactcaa aaagaaccag caaacagacc ccaaccctat agtgacaacg tcacactaaa
    34201 aatttacaac ataaagatga tataaagaca caccaagctt taccaagtaa cccacttgta
    34261 aagacagctc tatatttacc acgtaaagac aaaataaaga catacttatc tttatttgtg
    34321 ctttacatgg taaacccctt ggattataaa gacactgtaa agactaaatt atctttacga
    34381 aaaacacacg atgtaaagac agaaatatct ttacgtgagc tttacaacat aaagagagga
    34441 attgtgaaaa tgggtaaaat cttgcttgtc gtatcagata agggtggggt aggcaaaagc
    34501 acctacgtag ctaacacag
//
