LOCUS       NZ_CP056170            26712 bp    DNA     circular CON 04-APR-2024
DEFINITION  Enterobacter roggenkampii strain RHBSTW-00695 plasmid
            pRHBSTW-00695_3, complete sequence.
ACCESSION   NZ_CP056170
VERSION     NZ_CP056170.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15148685
            Assembly: GCF_013733395.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter roggenkampii
  ORGANISM  Enterobacter roggenkampii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 26712)
  AUTHORS   AbuOun,M., Jones,H., Stubberfield,E., Gilson,D., Shaw,L.P.,
            Hubbard,A.T.M., Chau,K.K., Sebra,R., Peto,T.E.A., Crook,D.W.,
            Read,D.S., Gweon,H.S., Walker,A.S., Stoesser,N., Smith,R.P.,
            Anjum,M.F. and On Behalf Of The Rehab,Consortium.
  TITLE     A genomic epidemiological study shows that prevalence of
            antimicrobial resistance in Enterobacterales is associated with the
            livestock host, as well as antimicrobial usage
  JOURNAL   Microb Genom 7 (10) (2021)
   PUBMED   34609275
REFERENCE   2  (bases 1 to 26712)
  AUTHORS   Shaw,L.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2020) Nuffield Department of Medicine, University
            of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.7
            Assembly Name                     :: WTP2 T2-00695
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 93.5654070765511x
            Sequencing Technology :: Hybrid: Illumina and OXFORD_NANOPORE
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013733395.1-RS_2024_04_04
            Annotation Date                   :: 04/04/2024 05:14:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,933
            CDSs (total)                      :: 4,818
            Genes (coding)                    :: 4,681
            CDSs (with protein)               :: 4,681
            Genes (RNA)                       :: 115
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 45 of 137
            Pseudo Genes (incomplete)         :: 74 of 137
            Pseudo Genes (internal stop)      :: 29 of 137
            Pseudo Genes (multiple problems)  :: 12 of 137
            Pseudo Genes (short protein)      :: 1 of 137
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP056170.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..26712
                     /organism="Enterobacter roggenkampii"
                     /mol_type="genomic DNA"
                     /strain="RHBSTW-00695"
                     /isolation_source="Wastewater effluent sample"
                     /db_xref="taxon:1812935"
                     /plasmid="pRHBSTW-00695_3"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
     gene            complement(join(26522..26712,1..196))
                     /locus_tag="HV268_RS24330"
                     /old_locus_tag="HV268_24335"
     CDS             complement(join(26522..26712,1..196))
                     /locus_tag="HV268_RS24330"
                     /old_locus_tag="HV268_24335"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF86 domain-containing protein"
                     /protein_id="WP_003100872.1"
                     /translation="MSENRLPDYLDHIQQAATDARSFVEGMAKDDFLADKRTQQAVIMS
                     LIVIGEAATKVMDGYVEFTQAHADVPWRSMRNMRNRMAHGYFDINLDVVWETVQEWLPA
                     LLQQLPAVRQDADDEDRNDKGMEP"
                     /name="DUF86 domain-containing protein"
     gene            complement(193..483)
                     /locus_tag="HV268_RS24335"
                     /old_locus_tag="HV268_24340"
     CDS             complement(193..483)
                     /locus_tag="HV268_RS24335"
                     /old_locus_tag="HV268_24340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="WP_001247892.1"
                     /translation="MRPSVVLDMKRSAVREAVGRFRAANPRVFGSVLHGTDRDGSDLDL
                     LVDALPGATLLDLGDLEEELKSLLGVDVDLLTPGDLPPKFRAKVLAEAQPI"
                     /name="nucleotidyltransferase"
     gene            620..1324
                     /locus_tag="HV268_RS24340"
                     /old_locus_tag="HV268_24345"
     CDS             620..1324
                     /locus_tag="HV268_RS24340"
                     /old_locus_tag="HV268_24345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_023327680.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWQMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(<1375..2418)
                     /locus_tag="HV268_RS24345"
                     /old_locus_tag="HV268_24350"
                     /pseudo=""
     CDS             complement(<1375..2418)
                     /locus_tag="HV268_RS24345"
                     /old_locus_tag="HV268_24350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229631.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /name="AAA family ATPase"
     gene            complement(2492..2908)
                     /locus_tag="HV268_RS24350"
                     /old_locus_tag="HV268_24355"
     CDS             complement(2492..2908)
                     /locus_tag="HV268_RS24350"
                     /old_locus_tag="HV268_24355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family toxin"
                     /protein_id="WP_016236302.1"
                     /translation="MNKTYMLDTCICSFIMREQPEAVLKRLELAVLRGQRIVVSAITYS
                     EMRFGATGPKASPRHVELVDAFCARLDAILPWDRAAVDATTEIKVALRMAGTPIGPNDT
                     AIAGHAIAAGAVLVTNNTREFERVPGLVLEDWVR"
                     /name="type II toxin-antitoxin system VapC family toxin"
     gene            complement(2905..3135)
                     /gene="vapB"
                     /locus_tag="HV268_RS24355"
                     /old_locus_tag="HV268_24360"
     CDS             complement(2905..3135)
                     /gene="vapB"
                     /locus_tag="HV268_RS24355"
                     /old_locus_tag="HV268_24360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_001261282.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVRP
                     TWGSFAQFEKADPDFMAEREDVVSDEGRFNL"
                     /name="vapB"
     gene            3092..>3304
                     /locus_tag="HV268_RS24360"
                     /old_locus_tag="HV268_24365"
                     /pseudo=""
     CDS             3092..>3304
                     /locus_tag="HV268_RS24360"
                     /old_locus_tag="HV268_24365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229628.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            3619..3933
                     /locus_tag="HV268_RS24365"
                     /old_locus_tag="HV268_24370"
     CDS             3619..3933
                     /locus_tag="HV268_RS24365"
                     /old_locus_tag="HV268_24370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013811190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_096152151.1"
                     /translation="MNNTIISFDTAFSAACFLQKQIGHRRLWITKFYVGFNGVGYYYAL
                     VDWDHRVLADWDQDSCHWDLRQDAWTVVPDSRDYCPEDVLTEVISEEQLFQLSTVEGFL
                     "
                     /name="hypothetical protein"
     gene            4028..4357
                     /locus_tag="HV268_RS24370"
                     /old_locus_tag="HV268_24375"
     CDS             4028..4357
                     /locus_tag="HV268_RS24370"
                     /old_locus_tag="HV268_24375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_096151727.1"
                     /translation="MCDLCRADGNYFHSAECVYDQLVSEYPVMWLRDSTRIGACYTLRE
                     LLSPEGMVLAIQNAPPVTGWRLRMRYNEATDEEIDPLRGDCTELPSRTDALLAFEPFRE
                     GATSV"
                     /name="hypothetical protein"
     gene            4406..5224
                     /locus_tag="HV268_RS24375"
                     /old_locus_tag="HV268_24380"
     CDS             4406..5224
                     /locus_tag="HV268_RS24375"
                     /old_locus_tag="HV268_24380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_096149273.1"
                     /translation="MGSMKDQMMDIESERFDKWLAENYPDVAPGSEEWEQAANLYYWEQ
                     EYLADQAQWDHEHGLFVASLNNVHQRYLHARQELKGLYTLLDTEQPELVYRMSFVHAVT
                     VMEAYLMYCARALLEEDLPLTRFRDEFYMKSDKIKNPVKHAARDMALSMFRPAAQNFVS
                     RMTFHNVKTIERYFGTVLHIPPVWPTEPLGIIADWRNDLVHRNGVDVHDVPRVISAPQL
                     QSALQKVSDLIEAADHSLRLEVDYFGNSRTEENREIIAEALRISPGGESS"
                     /name="hypothetical protein"
     gene            5224..5997
                     /locus_tag="HV268_RS24380"
                     /old_locus_tag="HV268_24385"
     CDS             5224..5997
                     /locus_tag="HV268_RS24380"
                     /old_locus_tag="HV268_24385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011251292.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="WP_008502207.1"
                     /translation="MTGLVTLGGYSTTGAQLPVSIDYPAALALRQMALVQDELPKYLLA
                     PEVSALLHYVPDLHRKMLLATLWNTGARINEALALTRSDFSLAPPYPFVQLATLKQRAE
                     KAARTAGRAPVGSQTHRLVPLSDANYVGQLEMMVATLKIPLERRNKRSGRTEKARIWEI
                     TDRTVRTWLSEAVEAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSI
                     SSTEVYTKVFALDVAARHRVQFQMPGDEAVALLKK"
                     /name="site-specific integrase"
     gene            complement(6074..6379)
                     /locus_tag="HV268_RS24385"
                     /old_locus_tag="HV268_24390"
     CDS             complement(6074..6379)
                     /locus_tag="HV268_RS24385"
                     /old_locus_tag="HV268_24390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_096152150.1"
                     /translation="MRNRAHTPPKDEASFINGGSAGLTAKNLDEPSIKPATSKAKPVSI
                     SLAEENLSSIDNVIREEMLSGNRRVNRSDVVRAAVMALENLSREEISQLIEKSRLK"
                     /name="hypothetical protein"
     gene            complement(6376..7002)
                     /locus_tag="HV268_RS24390"
                     /old_locus_tag="HV268_24395"
     CDS             complement(6376..7002)
                     /locus_tag="HV268_RS24390"
                     /old_locus_tag="HV268_24395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010260829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family plasmid-partitioning AAA ATPase"
                     /protein_id="WP_008502208.1"
                     /translation="MIIVLGSQKGGVGKSTLAVSIAAYLMALGKRVLIVDADDQKSVLT
                     WYNNRPENLPHMPVTGASGNIKAMLKEHEKSYDFVIADCAGRDSAEMRSGLMAADVFIS
                     PLRPSQMDLDVVPHTCSVFTAAKDFNESVRGYLVLNMTPTNMFVNEANQAADVLKDFPE
                     MNLSNARVCDRKAHRDAWAESMTIFETQNIKAQEEIEALVKEIIL"
                     /name="ParA family plasmid-partitioning AAA ATPase"
     gene            7235..8587
                     /locus_tag="HV268_RS24395"
                     /old_locus_tag="HV268_24400"
     CDS             7235..8587
                     /locus_tag="HV268_RS24395"
                     /old_locus_tag="HV268_24400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_181531669.1"
                     /translation="MDLVWKKNPRGRLERKLNLAEREALLHVFSNGRKPAQADLRIANS
                     VLEEMDRRKLWLKCDCVEHDPNIEGPFNCEVNVARLRHVKTTRQHDEQCPLFRLKKSKD
                     ADNTITEGKTSPLNPVGGNDWLPDKKKDTKITAVEGPVVPRKRRRKTLKPIPALGRKLL
                     TLIQAAGLNQLELVPEYKSPGLVGSVKRIKEVLDEHTMGNGTQLNMLFSCAPWLSLERI
                     NDMLTQLEVSLQTDSSDKESCVYIIGIATDASREEVTFSVRSNTFIHRPEARVSINGES
                     TYNTGSRAPYWAILEYRRGRDGKVYCHEGYAHAAYTLDNPVPVDSNKERDTLKVIINAS
                     SYAGRQENHPDAISLSKPLFTSKSTKNGVEEVIHPDFILNVVSSKENIVTTLIIETMGS
                     ESEEYVERKLQTHSWMEQEGVLLTDPPGWPEPSDRTFNSFLLKHIFSVSVQ"
                     /name="hypothetical protein"
     gene            complement(8614..10149)
                     /locus_tag="HV268_RS24400"
                     /old_locus_tag="HV268_24405"
     CDS             complement(8614..10149)
                     /locus_tag="HV268_RS24400"
                     /old_locus_tag="HV268_24405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549217.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="WP_001000409.1"
                     /translation="MNDTSSDDILLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLD
                     KLRRMNFGSRSEKVSRRIAQMEADLNLLQQESDTLTGRVDDPAVQRPLRQTRTRKPFPE
                     SLPRDEKRLLPTEPCCPECGGSLSYLGEDAAEQLELMRSAFRVIRTVREKHACRRCDRI
                     VQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYARQGVVLSRSVLSGWVDA
                     CCRLLAPLDEALQHYVLTDGKLHADDTPVPVLLPGNKKTKTGRLWTYVRDDRNAGSALA
                     PAVWFAYSPDRKGIHPQTHLAGFSGVLQADAYAGFNELYRDGHIKEAACWAHARRKIHD
                     VHVRTPSVLTEEALKRIGELYAIESEIRGKRAEERQAVRHQKVLPLLASLEGWLREKQK
                     TLSRHSELAKAFGYALNQWPALIRYAEDGWVEVDNNIAENALRRVSLGRKNWLFFGSDH
                     GGERGASLYSLIGTCKLNGVDPERYLHYVLDVIADWPVNRVGALLPWRVTLPA"
                     /name="IS66 family transposase"
     gene            complement(10199..10546)
                     /gene="tnpB"
                     /locus_tag="HV268_RS24405"
                     /old_locus_tag="HV268_24410"
     CDS             complement(10199..10546)
                     /gene="tnpB"
                     /locus_tag="HV268_RS24405"
                     /old_locus_tag="HV268_24410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004966400.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="WP_000609174.1"
                     /translation="MINLPAGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFI
                     FRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLMEGIDWRQ
                     PKRLLTSLTML"
                     /name="tnpB"
     gene            complement(11338..12093)
                     /gene="repE"
                     /locus_tag="HV268_RS24415"
                     /old_locus_tag="HV268_24420"
     CDS             complement(11338..12093)
                     /gene="repE"
                     /locus_tag="HV268_RS24415"
                     /old_locus_tag="HV268_24420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="WP_008502210.1"
                     /translation="MTEVAVINHKKRKNSPRIVQSNELTEAAYSLSRDQKRMLYLFVDQ
                     IRKSDGTLQEHDGICEIQVAKYAETFGLTSAEASKDIRQALKGFAGKEVVFYRPEEDAG
                     EEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNPYAM
                     RLYESLCQYRKPDGSGVVSLKIDWIMERYQLPQSYQRMPDFRRRFLQASVDEINSRTPM
                     RLSYIEKKKGRQTTHIVFSFSDIMSITPE"
                     /name="repE"
     gene            complement(12544..13788)
                     /locus_tag="HV268_RS24420"
                     /old_locus_tag="HV268_24425"
     CDS             complement(12544..13788)
                     /locus_tag="HV268_RS24420"
                     /old_locus_tag="HV268_24425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_181531671.1"
                     /translation="MYASCERVFRPDLKGKPVVVLSNNDGCVIARSAEAKPWIKMGTPW
                     FQMKNEKYPEKIYAFSSNYELYASMSARVMSCLEELAPRVEQYSIDEMFLDLTGVERCM
                     DLEDFGRQLRQHVYDCTRLTIGVGAGPTKTLAKSAQWASKEWKQFRGVLALTRGNPQRT
                     RKLLSLQPVEEIWGVGNRIARKLNVLGIKTALDLALMNPAFIRKNFSVVLERTVRELNG
                     ESCMSLEEAPPTKQQIVCSRSFGEKVTEYDSLRQAVCQYAERASEKLRKERQYCRHISV
                     FIKTSPFAVKEPYYGNVATEKLLTPTQDTRDIIAAATTALERIWKDGHRYAKAGVMLND
                     FTGSGVSQMQLFDERPPRPHSAELMKVLDGINHSGLGQVWFAGRGIAPAWQMKRDMLSP
                     AYTTRWKDIPIARIG"
                     /name="Y-family DNA polymerase"
     gene            14333..14686
                     /gene="arsR"
                     /locus_tag="HV268_RS24425"
                     /old_locus_tag="HV268_24430"
     ARG             14334..14683
                     /name="arsR"
                     /gene="arsR"
                     /gene_name="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="100.0"
                     /coverage="100.0"
     gene            14734..15096
                     /gene="arsD"
                     /locus_tag="HV268_RS24430"
                     /old_locus_tag="HV268_24435"
     ARG             14735..15093
                     /name="arsD"
                     /gene="arsD"
                     /gene_name="arsenite efflux transporter metallochaperone
                     ArsD"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="98.33"
                     /coverage="100.0"
     gene            15114..16865
                     /gene="arsA"
                     /locus_tag="HV268_RS24435"
                     /old_locus_tag="HV268_24440"
     ARG             15115..16862
                     /name="arsA"
                     /gene="arsA"
                     /gene_name="arsenite efflux transporter ATPase subunit
                     ArsA"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.14"
                     /coverage="100.0"
     gene            16914..18203
                     /gene="arsB"
                     /locus_tag="HV268_RS24440"
                     /old_locus_tag="HV268_24445"
     ARG             16915..18200
                     /name="arsB"
                     /gene="arsB"
                     /gene_name="arsenite efflux transporter membrane subunit
                     ArsB"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="98.37"
                     /coverage="100.0"
     gene            18216..18641
                     /gene="arsC"
                     /locus_tag="HV268_RS24445"
                     /old_locus_tag="HV268_24450"
     ARG             18217..18638
                     /name="arsC"
                     /gene="arsC"
                     /gene_name="glutaredoxin-dependent arsenate reductase"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.29"
                     /coverage="100.0"
     gene            complement(18672..>18965)
                     /locus_tag="HV268_RS24450"
                     /old_locus_tag="HV268_24455"
                     /pseudo=""
     CDS             complement(18672..>18965)
                     /locus_tag="HV268_RS24450"
                     /old_locus_tag="HV268_24455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001057013.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ArsA-related P-loop ATPase"
                     /name="ArsA-related P-loop ATPase"
     gene            complement(19081..19653)
                     /locus_tag="HV268_RS24455"
                     /old_locus_tag="HV268_24460"
     CDS             complement(19081..19653)
                     /locus_tag="HV268_RS24455"
                     /old_locus_tag="HV268_24460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556711.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001556711.1"
                     /translation="MRLFGYARVSTSQQSLDIQIKGLKEAGVKASRIFTDKASGSSTDR
                     KGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGEMG
                     KMVVTILSAVAQAERRRILERTNEGRQEARLKGIRFGRKRIIDRNSVLALHQQGTGATD
                     IARRLSIARSTVYKILEDESRVNLSKI"
                     /name="recombinase family protein"
     gene            19817..22825
                     /locus_tag="HV268_RS24460"
                     /old_locus_tag="HV268_24465"
     CDS             19817..22825
                     /locus_tag="HV268_RS24460"
                     /old_locus_tag="HV268_24465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012817690.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="WP_001556712.1"
                     /translation="MPVDFLTTEQELNYGRYVAEPNDVQLARYFHLDERDLAFINQRRG
                     RHNRLGIALQLTTARFLGTFLTDLTRVLPGVQQFVAVQLNIRRPEVLTRYAERVTTLRE
                     HTALIKEYYGYHEFGDFPWSFRLKRLLYTRAWLSNERPGLMFDFATAWLLQNKVLLPGA
                     TTLVRLVSEIRERANQRLWKKLAALPDSWQTARVTELLDIPEGQRTSPLEQLKKGPVTV
                     SGPAFTEALERYIRLRNLEFSRLNFTGLPAIQLRNLARYAGMASVKYIARMPQQRKLAV
                     LTAFVKAQETAALDEAVDVLDMLILDITRAAKKTGQKKRLRTLKDLDRAALILARACSL
                     LLDEQADDAELRETIFNSIPKSRLAESVSKVNELARPQNNNFHDEMVEQYGRVKRFLPA
                     VLRDLHFQAAPAGEHTLSAIHYLTELNGSKKRILDNAPEHIITGPWKRLVYDAEGRIQR
                     AGYSLCLLERLQDALRRRDIWLENSDRWGNPREKLLQGEEWQAQRVPVCRALGHPTDGH
                     KGVQQLAVQLDETWKTVASRFEGNAEVHICHDGKHPSLTISSLEKLEEPTSLHRLNSRV
                     RLLLPPVDLTELLLEIDARTGFTREFTHVSESGARAQDLHISLCAVLMAEACNIGLEPL
                     IKHNIPALTRHRLSWVKQNYLRAETLVSANARLVDFQSTLELAGRWGGGEVASADGMRF
                     VTPVKTVNSGPNRKYFGSGRGITWYNFVSDQYSGFHGIVVPGTLRDSIFVLEGLLEQQT
                     GLNPVEIMTDTAGTSDIIFGLFWLLGYQFSPRLADAGEAVFWRVDKSANYGALDELARG
                     CADLSKAEDQWDEMMRTAGSLKLGTIHASELIRSLLKSSRPSGLAQAIMEVGRVNKTLY
                     LLNYIDDEDYRRRILTQLNRGEGRHAVARAICYGQRGEIRKRYREGQEDQLGALGLVTN
                     AVVLWNTLYMQEALSWIRSNGEEIGVEDIARLSPLMHGHINMLGHYTFTLPEDILKGEL
                     RELNFNLNNELTS"
                     /name="Tn3 family transposase"
     gene            complement(22858..23853)
                     /locus_tag="HV268_RS24465"
                     /old_locus_tag="HV268_24470"
     CDS             complement(22858..23853)
                     /locus_tag="HV268_RS24465"
                     /old_locus_tag="HV268_24470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS5075 family transposase"
                     /protein_id="WP_121933010.1"
                     /translation="MENIALIGIDLGKNSFHIHCQDHRGKAVYRKKFTRPKLIEFLATC
                     PATTIAMEACGGSHFMARKLAELGHFPKLISPQFVRPFVKSNKNDFVDAEAICEAASRP
                     SMRFVQPRTESQQAMRALHRVRESLVQDKVKTTNQMHAFLLEFGISVPRGAAVISRLST
                     LLEDSSLPLYLSQLLLKLQQHYHYLVEQIKDLESQLKRKLDEDEVGQRLLSIPCVGTLT
                     ASTISTEIGDGKQYASSRDFAAATGLVPRQYSTGGRTTLLGISKRGNKKIRTLLVQCAR
                     VFIQKLEHQSGKLADWVRELLCRKSNFVVTCALANKLARIAWALTARQQT"
                     /name="IS110-like element IS5075 family transposase"
     gene            complement(23932..24489)
                     /locus_tag="HV268_RS24470"
                     /old_locus_tag="HV268_24475"
     CDS             complement(23932..24489)
                     /locus_tag="HV268_RS24470"
                     /old_locus_tag="HV268_24475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019897068.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_003100847.1"
                     /translation="MLIGYARVSTQDQNLELQREALSKAGCKKVFEDKVSGTRADRPGL
                     AKTLEMLREGDTLVVWKLDRLGRSVKQLVDLVGDLHKHGVQFRSLTDSIDTGTPSGRFF
                     FHVMASLAEMERELTVERTRAGLEVAKQLGRKGGRKPKMTDSKIESAKKLLASGVPPKD
                     VAKNLGVSIPTLYRWVPASTHA"
                     /name="recombinase family protein"
     gene            complement(24483..24854)
                     /locus_tag="HV268_RS24475"
                     /old_locus_tag="HV268_24480"
     CDS             complement(24483..24854)
                     /locus_tag="HV268_RS24475"
                     /old_locus_tag="HV268_24480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_003100853.1"
                     /translation="MSTSTIEALASAWARIAEEAEFPADYEGTATPQAHRASEAIQEQI
                     RERIVATNDMRLFSLLHLLGQASLRMEQALWPEDYERMTREVEEALRQATDANARSYTH
                     EEVMQAMQERIDRARDKPC"
                     /name="hypothetical protein"
     gene            complement(24851..25351)
                     /locus_tag="HV268_RS24480"
                     /old_locus_tag="HV268_24485"
     CDS             complement(24851..25351)
                     /locus_tag="HV268_RS24480"
                     /old_locus_tag="HV268_24485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_003100856.1"
                     /translation="MKLSFHQHIALFWMIGAPGVFAPVIENAKRPDAGAVMAWGVAIVA
                     VMILFTPLLLRCPPFRRWYGRTDALSERQRQALAERGLRRYYQTAFDDGYVPRVMPYVW
                     RIIWTVGGLMAVTAVLPTNTGRPAFDALVVFSTWYPIGVMLLVFASRPLGRLIRQRAQE
                     RRK"
                     /name="hypothetical protein"
     gene            complement(25348..25674)
                     /locus_tag="HV268_RS24485"
                     /old_locus_tag="HV268_24490"
     CDS             complement(25348..25674)
                     /locus_tag="HV268_RS24485"
                     /old_locus_tag="HV268_24490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011809177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_003100858.1"
                     /translation="MSRSRRKTPIVGHTTCGSEREDKKLWHQRWRTRERTALTSASPEA
                     LSAHLPLLENQASSVWSMGKDGRSYWPVKRQAATADRIANHKGRNPQERASLKKRLLRK
                     WMSK"
                     /name="hypothetical protein"
     gene            complement(25929..26285)
                     /locus_tag="HV268_RS24490"
                     /old_locus_tag="HV268_24495"
     CDS             complement(25929..26285)
                     /locus_tag="HV268_RS24490"
                     /old_locus_tag="HV268_24495"
                     /function="Uncharacterized conserved protein, contains
                     double-stranded beta-helix domain"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003465043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="WP_003465043.1"
                     /translation="MTVESRIFSVAEYVQPSEGEPIRSVVLETRDSIIVVWHVHPGQEI
                     AAHIHPHGQDTWTVLSGMADYFQGNGIVRALREGEIAVARPGQVHGARNTGTEPFVFVS
                     VVASANAGFVLAER"
                     /name="cupin domain-containing protein"
     Typing          complement(11360..12064)
                     /name="rep_cluster_2268"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="80.737"
                     /coverage="95.0"
                     /evalue="5.29e-154"
ORIGIN
        1 cctgggtgaa ctcgacgtag ccatccatca cctttgtggc cgcctcgccg atgacgatca
       61 ggctcatgat gacggcctgc tgggtgcgct tgtcggccaa gaagtcgtcc ttggccatcc
      121 cttccacgaa gctgcgcgca tcggttgcgg cctgctgaat gtggtcgagg taatcgggca
      181 ggcggttctc gctcatatcg gttgcgcctc cgcgagcacc ttggcccgga acttcggcgg
      241 caggtcgccg ggagtcagca gatcgacgtc aacgccgagc agcgatttca gttcttcttc
      301 caaatcgccc aagtccaaca acgtggcacc gggcagcgca tcgaccaaca ggtcgaggtc
      361 gctgccatcc cggtcggtgc catgcagcac cgagccgaag acgcgcgggt tcgcggcgcg
      421 aaagcggcct accgcttcac gcactgcgct tcgcttcatg tcaagcacaa cagacggtcg
      481 catgcgcatc ctttcttatc gaaactcgtt gagatgatat gcaatcaaga atagaatttc
      541 aagagctatt ttcgagggca ctgttgcaaa tagtcggtgg tgataaactt atcatcccct
      601 tttgctgatg gagctgcaca tgaacccatt caaaggccgg cattttcagc gtgacatcat
      661 tctgtgggcc gtacgctggt actgcaaata cggcatcagt taccgtgagc tgcaggagat
      721 gctggctgaa cgcggagtga atgtcgatca ctccacgatt taccgctggg ttcagcgtta
      781 tgcgcctgaa atggaaaaac ggctgcgctg gtactggcgt aacccttccg atctttgccc
      841 gtggcaaatg gatgaaacct acgtgaaggt caatggccgc tgggcgtatc tgtaccgggc
      901 cgtcgacagc cggggccgca ctgtcgattt ttatctctcc tcccgtcgta acagcaaagc
      961 tgcataccgg tttctgggta aaatcctcaa caacgtgaag aagtggcaga tcccgcgatt
     1021 catcaacacg gataaagcgc ccgcctatgg tcgcgcgctt gctctgctca aacgcgaagg
     1081 ccggtgcccg tctgacgttg aacaccgaca gattaagtac cggaacaacg tgattgaatg
     1141 cgatcatggc aaactgaaac ggataatcgg cgccacgctg ggatttaaat ccatgaagac
     1201 ggcttacgcc accatcaaag gtattgaggt gatgcgtgca ctacgcaaag gccaggcctc
     1261 agcattttat tatggtgatc ccctgggcga aatgcgcctg gtaagcagag tttttgaaat
     1321 gtaaggcctt tgaataagac aaaacgctgc ctcatcgcta actttgcaac agtgccagaa
     1381 ggcggcagtc tcagcggaaa gttcattcat cagtaccggc cgggcagacc cgaggaggat
     1441 tgccttacgc agatcgaggc gggaggagat atggctgctg tgtgtggcaa taaacacctg
     1501 cgtctgccgt tcagtggcaa gctgattaac cagcctcttc atactgacat ggctgagatg
     1561 attttccggc tcctcaagca acagtacgtg gagctctccc tgctgctgat gccgctgcag
     1621 cgcaaactcc gttttgatga agcactgcct tccttttcca cggtgacgaa tggaaatacc
     1681 gtcctcggta atgtccagat tcgcctcaag ccctgattta gcaccggaac gcacgccaaa
     1741 ctgatacgtt tccagcgtgt cgtttatggc tgacagatgc cgggtgcaga agtgcatttt
     1801 ctgttgccgg taactgtttt caagccggta ccgatcggcc accggcacat tgacgctgta
     1861 aactgtgcgc gtatattcct gtgcggcgtg ctcgttatcg atgcgtgcac tgtctaagag
     1921 cagatggcgc agatagcgtc tgaagctggc gaaatgacca ccggagaagg tgctgaaccg
     1981 cacggaatag tattcatagg gaaaattatc gggatcctgc tgtagtacat tgtgaatatc
     2041 ctggccgtat tcctccgtca ttggtgcaat acgcattctg agaccatccg cattgatacc
     2101 cgccagattt tgcctgccgt tcaggtcagg atctccccca ttactcagga aaacgtcagc
     2161 tgtcagcacg ggtaactgat cggcgcggcg ctcaccttcc tgaaacagcc ttactgctga
     2221 ctgggacagg agcgattcca cacccaatgc ctcgacccgg tgccggctgt cactcagcac
     2281 aaggtcaagg gccagcagaa tcgtgctttt cccggactca ttgtccccga ccagaatgtt
     2341 acggtcatga gtgaagcgca ggtccagttc cggaaacttt ttaaagtttt gcagcataag
     2401 ccgcgtgatc agaggcatct tttattcctt tatataccgc tgactgaaag agtgtccggc
     2461 tgcgccagac cgcctgtttt gttttacagc gttatcttac ccagtcttcc agcacaagac
     2521 ccggtacccg ctcaaattcc cgcgtattat tcgtcaccag cacggcaccg gcggcgatgg
     2581 cgtgcccggc aatggccgtg tcgttcgggc cgatcggcgt cccggccatt cgcagcgcca
     2641 ccttaatctc cgtggtggcg tccaccgcag cgcgatccca gggcaggatg gcatcgaggc
     2701 gggcgcagaa cgcgtcgacc agctcgacgt ggcgcgggga ggccttcggg ccggtggccc
     2761 cgaagcgcat ttcagaataa gtgatggccg agacaacgat gcgctggccg cgcagcaccg
     2821 ccagctccag gcgcttcagg acggcttccg gctgctcgcg catgatgaac gagcagatac
     2881 aggtgtcgag catataggtc ttgttcacag gttaaatcgt ccttcgtcgc tgacaacgtc
     2941 ctcgcgctcc gccataaagt ccgggtctgc cttctcgaac tgcgcgaacg agccccaggt
     3001 cggccggacg ggacgcaaaa taatgctgtc cccttcccgg acgatctcca gctcgctcac
     3061 tccctcaaaa tccagatcgc ggggcagacg aatggcgcgg ttattgccgt ttttaaaaat
     3121 ggatacagtt ctcatcattt cctcctggcc gaccggcctg tatgactatg ttcagtatat
     3181 gcagatgcaa agcatatgta tagtcatagc atatgcagat ggtaagtata tgcgtatgcc
     3241 acacctatgc agatgcccgg catatggata tgttaaacct atacatagtt ctctcttttt
     3301 ctgctgagat ccgaaaaaag ctagttccgg atcttgaata tttttagatc agttttctga
     3361 aacgaaaccg aaaaatgtgc tataatatat agagttagta gttgttgact gacgggcgtt
     3421 acgtgtacgg tcggatgatg ctggtactgt gatggacttt cctgtttccg attatctgaa
     3481 ataggagagt tttcggaaag tccggttaag gttgtcaggt aattccgatg ggaaactgtt
     3541 tcactgctaa cggtaaacat ctgctgacat gaagtcacag atgaaattat aatcgttcaa
     3601 ctgataagga tatcaactat gaacaataca attattagtt ttgatactgc tttttcggca
     3661 gcgtgttttc ttcaaaagca gattggtcat cgtcgtcttt ggatcaccaa gttttatgtg
     3721 ggattcaatg gcgttggata ctactacgct cttgttgact gggatcaccg tgtgcttgcg
     3781 gactgggatc aggattcatg tcactgggat ttacgtcagg atgcctggac tgttgttcca
     3841 gacagcaggg actattgccc ggaagatgtg ttgactgagg tcatttctga ggagcaactc
     3901 tttcagctct ccaccgtgga aggcttttta taatcaggag gggcttagcc cctccttttt
     3961 tttaatagtt acagggactg ctaaaaatga atgatggcag gcgggatttc tcagtagagg
     4021 aagggttatg tgtgatttat gcagggcgga cggaaattac tttcactcgg ctgaatgcgt
     4081 atatgaccag ctggtcagtg agtaccccgt gatgtggctg cgggactcga cccggatcgg
     4141 cgcctgctac acgctccgtg agctgctgtc gccggaaggg atggtgctgg ccatacagaa
     4201 cgcgcctccc gtgacgggat ggcggctgcg tatgcggtat aacgaggcca cagatgaaga
     4261 gatcgacccg ctgcgcgggg actgtaccga gctgccctcc aggacggacg ccctgttggc
     4321 ctttgagccg ttccgtgaag gcgctacgtc agtatgaccg gcgggatttt tcatttacag
     4381 aaccatacag aagggtactg gcattatggg aagcatgaaa gaccagatga tggatattga
     4441 atctgaacga tttgataaat ggcttgcgga aaattatccg gatgttgcac ccggctcaga
     4501 agaatgggaa caggccgcta acctttatta ctgggaacag gagtatctcg ccgatcaggc
     4561 tcagtgggat catgaacacg ggctgtttgt ggcttccctg aacaatgttc atcagcgtta
     4621 ccttcacgcc aggcaggagt tgaaggggct gtataccctg ctcgatacag agcagcctga
     4681 actggtgtac aggatgtctt tcgtccatgc cgtgacggtc atggaggcgt acctgatgta
     4741 ctgcgccagg gctctgctgg aagaggattt gccgcttaca cggttcaggg atgagtttta
     4801 tatgaagtcc gataaaatca aaaatccggt aaaacatgct gcccgtgaca tggctctttc
     4861 tatgttccgg cctgcggcgc agaattttgt ttcccggatg acgtttcata acgtaaaaac
     4921 cattgagcgc tatttcggga ctgtgcttca tataccgccc gtctggccaa ctgagccgct
     4981 gggtatcatc gcagactggc gaaacgatct ggtacaccgc aacggtgtgg atgtgcatga
     5041 tgtgccacga gtgatatcag cgccgcagct gcaaagcgcc ctgcagaaag tgtcggatct
     5101 gatagaggct gcagatcatt ccctgcgtct ggaagtggac tattttggta actcgcgtac
     5161 cgaagaaaac cgggaaatca ttgcggaagc actgcgcata tccccgggcg gagaatcatc
     5221 ctgatgaccg gactcgttac cctgggaggg tattcgacca caggggctca gttacctgtt
     5281 tctatcgact acccggcggc gctggccctg cgtcagatgg cactggttca ggacgaactg
     5341 ccgaaatacc tgctggcccc ggaagtgagt gccctgctcc actatgtgcc cgaccttcac
     5401 cgcaagatgc ttcttgctac cctgtggaac accggcgccc gtattaacga agcactggcc
     5461 ctgacccgga gtgatttttc cctggcaccg ccctatccgt tcgtgcagct ggccacactc
     5521 aaacaaaggg ctgaaaaagc cgccagaacg gctggccgtg cgcccgtcgg cagtcagact
     5581 caccggctgg taccgctttc tgatgcgaat tatgtcggtc aactggagat gatggtggcc
     5641 acgctgaaaa ttcctcttga acgacgtaat aagcgaagcg gcagaaccga gaaggcacgc
     5701 atctgggaga tcaccgaccg gacggtccgc acctggctca gcgaagcagt tgaagccgca
     5761 gcggccgacg gggtgacgtt ctccgtgccg gtgaccccgc acacgttccg tcattcctac
     5821 gcgatgcaca tgctgtatgc cggtatacca ctgaaggtgc tgcagagttt gatggggcat
     5881 aagagcatca gttcgactga ggtgtatacg aaggtgtttg cgctcgatgt cgcggcacgg
     5941 caccgggtgc agttccagat gccgggcgat gaggcggtag cgttgctaaa aaaatagatg
     6001 attaagatag caagatagta ttttattatc ttgctatctt attaagttat taagttatta
     6061 agttattaag ttattatttt aatctagatt tttcaatgag ttgagatatt tcttctcgcg
     6121 ataaattttc taacgccatc actgcagctc taactacatc tgatctattg actctcctgt
     6181 tccctgataa catctcttcc cttatgacat tatcaattga gctaagattc tcttcagcaa
     6241 gagagatgct gactggtttt gctttactag tcgcaggttt aatacttggt tcgtcaagat
     6301 tttttgcagt aaggccagct gaacctccat ttataaacga agcttcatcc tttggcggcg
     6361 tatgtgctct atttctcaca gaatgatctc cttaaccaga gcttcaattt cttcttgggc
     6421 tttgatgttc tgtgtttcaa aaatagtcat tgattcggcc caggcatccc tgtgagcttt
     6481 tctgtcacat acgcgagcat tagacagatt catttccgga aagtctttga gaacatccgc
     6541 cgcctgatta gcttcattaa cgaacatgtt agttggtgtc atattcaaca ctaaataccc
     6601 acgtacagac tcgttgaaat ctttagcagc agtaaaaaca gagcatgtat gaggtacaac
     6661 atccaaatcc atttgggacg gtcgtaaagg ggaaataaac acatctgcag ccattaatcc
     6721 acttcgcatc tctgcactgt cacggccagc acaatcggcg attacaaagt cataagattt
     6781 ttcatgctct ttaagcatgg ctttgatgtt gccggacgct ccagtcacag gcatatgagg
     6841 caagttctct ggtcgattgt tataccaggt cagcactgat ttttgatcgt cggcatctac
     6901 aatgagaact cgctttccta atgccataag atatgcagcg atggaaactg cgagcgtact
     6961 tttacctact ccaccttttt gactaccaag aacaatgatc atattccgca caccttgttt
     7021 gttatcttat taagataata ggataacaaa cattaatttt caatatgcgc cggagttgat
     7081 attttgttaa catgctaact tagcatgtta acaactacat taaattcaat taattagaat
     7141 acaatattac catcttgcga tattaataag atattacgat aacaagatac tatcttgtta
     7201 tcgtaatcgc acttttgagt gaaggagtaa agcaatggac ctggtgtgga aaaaaaatcc
     7261 aaggggaagg cttgaaagga aactgaatct ggcagagaga gaggcattgc tgcatgtgtt
     7321 cagcaacggt cgaaaacccg ctcaggctga tttacgtata gcaaattctg tgcttgaaga
     7381 aatggaccgc cgtaagttgt ggttaaaatg cgattgcgtc gaacatgacc cgaacattga
     7441 aggtcctttt aactgcgagg ttaacgttgc caggttacgc cacgtcaaga cgacaagaca
     7501 gcatgatgaa cagtgccctt tgttcaggct aaagaaaagt aaggacgctg ataacactat
     7561 cactgaagga aaaaccagcc cactaaatcc ggttggcggt aatgactggt tacctgacaa
     7621 gaagaaagac accaaaatca ccgctgtgga agggccggta gtgccccgta agcgtcgacg
     7681 caaaactctt aaacccattc cggctctggg ccgaaaattg ctgactctca ttcaggcagc
     7741 tggcctgaac caacttgaac tagtacctga atataaaagt ccggggttag tcggttcggt
     7801 caaaagaata aaagaagttc tggatgaaca tacaatgggc aatggaacac agcttaatat
     7861 gctgttcagt tgcgcgccct ggctgtccct cgaacggatt aacgacatgc tgactcagct
     7921 ggaagtctca ctgcagactg atagcagtga taaggagtca tgcgtgtata tcattggtat
     7981 tgcgaccgat gccagtcggg aagaagtaac ctttagcgtt cggagtaata cttttatcca
     8041 taggcctgaa gcccgagtca gtatcaatgg agaaagcacc tacaacactg gcagtcgggc
     8101 cccatactgg gcaattctgg aataccgcag aggtagggat ggcaaggttt actgccatga
     8161 gggctatgcg catgctgcgt atacgcttga taatcctgtg cctgtggata gcaacaaaga
     8221 acgcgacaca ctgaaggtaa taataaacgc cagcagctat gctggccgtc aggaaaatca
     8281 tccggatgct atcagcctca gcaagccact tttcacgtct aaaagcacta aaaatggggt
     8341 ggaggaggtc attcatcctg acttcatact gaatgtagtt tcgagcaaag aaaacatcgt
     8401 taccactttg atcatcgaaa caatgggctc tgaatccgag gagtatgtcg agcgtaaact
     8461 gcaaacacat agctggatgg agcaggaagg tgtgctctta actgatcctc cgggttggcc
     8521 agaaccttca gacaggacat ttaacagctt cctgctcaaa cacattttta gtgtaagcgt
     8581 gcagtgagaa ccgtattgac gaagtgaagc tggtcaggca ggcagagtaa cccgccacgg
     8641 gagcagagca cccacccggt tcacaggcca gtcggcgatg acatcaagta cataatgcag
     8701 atagcgttcc ggatccacgc cgtttaattt gcacgtcccg ataagactgt acagtgacgc
     8761 accgcgctca ccaccatgat ccgagccgaa gaacagccag ttttttctcc ccagactgac
     8821 ccgtcgtagg gcgttttcgg caatgttatt atccacctcc acccagccat cttctgcata
     8881 gcggatcagc gccggccact ggttcagcgc atacccgaac gccttcgcca gttctgagtg
     8941 ccttgagagg gttttctgtt tctcccgcag ccacccctcc agtgacgcca gcagcggcag
     9001 cactttttgg tgccggactg cctgccgttc ctctgctctt ttacctctga tctccgactc
     9061 gatggcatac agctcgccga tccgtttcag cgcctcctcc gtcaggactg acggggtacg
     9121 gacgtgaaca tcgtggattt ttcggcgggc atgggcccag cacgcggctt cctttatatg
     9181 gccgtcgcgg tagagctcgt tgaacccggc gtaggcatca gcctgcagta cgccactgaa
     9241 gcctgcaaga tgggtctgag ggtggatacc ttttctgtcc gggctgtaag cgaaccacac
     9301 tgcgggggcc agcgctgatc cggcgttgcg gtcgtctcga acgtacgtcc ataagcgccc
     9361 ggtcttcgtc ttcttattgc ccggcaacag caccgggaca ggcgtatcgt cagcatggag
     9421 tttgccgtcg gtcaggacat agtgctgaag ggcttcatcc agcggtgcca gcagacgaca
     9481 acacgcatcc acccagcccg acagtacaga acgactcaac actacaccct ggcgggcata
     9541 gatctccgac tggcgataca gcggtgtgtg ctctgcatac tttgaggtca gcactcgggc
     9601 cagcagcccc ggtccggcga tcccccgttc gatggggcgc gaaggagccg gggcctgaac
     9661 gatgcgatcg caccgacggc aggcatgctt ttcacggact gtccggataa cccggaaggc
     9721 gctgcgcatc agctccagct gttcggcggc atcctcaccc aggtaactca gcgaaccacc
     9781 gcactccggg caacacggct cagtcggcag cagccgcttc tcatcccgtg ggagtgactc
     9841 agggaacggt ttgcgggtgc gggtctgacg cagcgggcgc tgcactgccg ggtcatccac
     9901 ccggccggtc agcgtatcgc tttcctgctg cagcaggttc aggtcagctt ccatttgcgc
     9961 gatacggcgg gatacctttt cggaacgact gccgaagttc atccggcgca gcttatccag
    10021 ttgcgcctgc agatggtcta tttcgcgttc ccggttgctc agcttttcct gcagggcgtg
    10081 gatcaacgct tcctgttcgg ccaggcgctg tttcagcaga aggatgtcgt cagaagaggt
    10141 atcgttcata agcctgtatt ttaccaggct tattctgcga caaccaggat aaagagcgct
    10201 acaacatggt cagggatgtc agtaaccgct ttggctgtcg ccagtcgata ccttccatca
    10261 gcatcgccag ttgcgccggc gtcaggaaca ctttgccatc gcgggctgag ggccaggcga
    10321 agcgaccacg ttccagtcgc tttgtcagca ggcacagacc atcgccggtg gaccagagca
    10381 gttttacctg actgccgctg cgtccccgga agatgaagac gtggccggac atcgggtcat
    10441 ctttcagcgc ggtctgcacc tttgcggcga ggccattgaa gccgttgcgc atatcggtga
    10501 taccggcaac cagccagatt tttgtgcctg cgggaagatt tatcataccg gcccccgcat
    10561 cagttcgcgc aggacagtgc tcatgagttc agcagaggga tgagtcagtg ttatttctcc
    10621 tccccgacat tttatgtggc aggtagcggg aggagagcag gatggtagtt cgaaggttgg
    10681 gagagaagag cccgcctgaa gctgcacggg tatcagggca ggaagcgacg atgagttttt
    10741 tcggggccga cagacccgcc cttcacgctg ccagagcctt atccatttaa agagcaggtt
    10801 atcattgacg tcatgtttcc gggccagtgc ggcaatactg ccttcttctt caagagccag
    10861 cctgaccagt tccattttga attcagggga atagtgtttc cggggaagtc tttctttagc
    10921 gcgcatgagg tgtccacctg cgaaataagt gggtgcttaa gttacaggat cctggattcg
    10981 ggaccagacg gtactcagac gacgcttact ttttagtgca gggaaaatgc acaaatagtt
    11041 caggcagcgg ttttgaattc aaatagtgac aatgcaccct cagccagaag tggaaaggac
    11101 gcacttaagt gtgacaaacg acactcaggg ctgaggggat atgtgacaag ctgcactgaa
    11161 ctaaatgtga caaattgccc tcattaagtg tatttaaagc acaaaattgg aaccatgtag
    11221 ttccagaaaa ccagtcaggg caaaggaaga caaactgttc tgtgacaaat caccctgaga
    11281 gctttaactc tagtgtgaca aaccaccctg ctaattgtga caaatcaccc tcaaaactca
    11341 ctcaggtgta atcgacatta tgtcgctgaa agaaaagact atatgagtcg tctggcgtcc
    11401 tttctttttc tctatataag acaggcgcat tggcgttctg ctgttaatct catcgacact
    11461 cgcctgcagg aacctacggc gaaagtccgg catacgctga taactttgcg gaagctgata
    11521 gcgctccatg atccagtcta ttttcaggga taccacgcca gagccatccg gcttacggta
    11581 ctggcataat gactcgtaca ggcgcatggc atagggattg gtgatctctt tcgtttcact
    11641 tagtcggaac tgtgtgaaac ggttctgaag gccaataaag aaaggaatga ggtacgggtt
    11701 aatatgaacg ctgtagagcc ctctggaggg actatgggca cgtttgatga accagggaaa
    11761 ggactcataa cctttttctt ccccggcatc ctcttcaggc cgataaaaga ccacttcttt
    11821 acccgcgaat cccttgagag cctgacggat atctttgctt gcctcggcgg aggtcaaccc
    11881 gaaggtttcc gcatacttgg cgacctgaat ttcacatata ccgtcatgct cctgcagcgt
    11941 accgtcagat tttctgatct ggtccacaaa gagataaagc atacgctttt gatcgcgaga
    12001 tagactgtat gccgcctcag tcagttcgtt tgactggaca attcgcgggc tattcttacg
    12061 ttttttatgg ttgataaccg caacttccgt catgacaggt ccgtgtaaag tgtgacagga
    12121 atttagattg tcacactaat tgaaaaagag tcaacaggtt gggataactt tgtggaatac
    12181 aacaaatcat gagggcaatt tgtcacaggg ttaagggcaa tctgtcacac tttaagatgg
    12241 agattgaggg tgatttgtca cactgaaagg gcagattgtc acacagatcc ttctcaaacc
    12301 cgcatgaata aagggctgag aggtgttcta aaaaggtaaa cctaacaaca ctttaaaaag
    12361 atcttataaa aatatgcccg tggataagta gataagtgga taaacagagt ggggtatcca
    12421 ttaaacacct agcgtaagca gaatttgtcc gtgcagttcc ctggtgcttc ctcgctcact
    12481 cgcgggcttc gccctgtcgt tcggctgcgg cgagcactac tggctctctc tgaaaggcga
    12541 aatttaaccg atcctcgcta tggggatatc tttccagcgt gtggtgtacg caggggagag
    12601 catatcgcgt ttcatctgcc atgcaggcgc aatacctcgt cctgcaaacc agacctgtcc
    12661 cagtccggaa tgattaatgc catcaagaac cttcatcagc tcagcgctgt gaggacgtgg
    12721 cggacgttcg tcgaacagct gcatctgcga aacgccggag ccggtgaagt cattcagcat
    12781 cacaccggct tttgcatacc ggtgcccgtc cttccagatt cgctccagag ccgttgtggc
    12841 ggccgcaatg atgtcccggg tgtcctgagt gggtgtaagc agtttctccg tggccacgtt
    12901 gccgtagtaa ggctctttaa cggcgaacgg agacgttttg atgaaaacgg aaatatgccg
    12961 gcagtactgg cgctctttac gcagcttttc tgaggcccgt tctgcgtact gacagacagc
    13021 ctggcgcagc gaatcgtatt cagtgacctt ctcgccgaag ctacggctgc agacgatctg
    13081 ctgctttgtt ggcggggctt cttcaagcga catgcagctt tccccgttca gttcacgtac
    13141 tgttcgctcg agaacgacgg agaaattttt gcggataaag gccgggttca tcagggccag
    13201 atcgagcgcg gttttgatgc ccagaacatt gagctttcgt gcaatacggt ttcccacccc
    13261 ccagatctct tcgaccggct gcagtgaaag cagtttccgc gttcgctgag gattcccccg
    13321 ggtcagtgcg agcacaccac gaaactgttt ccactccttt gaggcccact gggctgattt
    13381 tgccagggtt ttcgtcggcc cggcacccac gccgatggtc agacgggtac agtcatacac
    13441 gtgctggcgc agctgccggc cgaagtcctc caggtccatg cagcgctcaa cgccggtcag
    13501 gtcgaggaac atctcgtcaa tcgaatactg ttccaccctg ggggccagct cctccaggca
    13561 gctcatcacg cgcgctgaca tcgaggcata aagttcatag ttgcttgaga acgcgtatat
    13621 tttttccggg tacttttcgt ttttcatctg aaaccacggc gtgcccattt tgatccaggg
    13681 ctttgcctcg gcacttcttg cgatgacgca gccatcgtta ttactgagca ccacaaccgg
    13741 ctttcctttc aaatcagggc ggaaaacacg ttcgcagctg gcataaatct atggtcactc
    13801 ccgtttttgc aacaccgatt ttgacgataa gttggcttgc ttgaatctat ccggcgtctg
    13861 aatgggattt tattcccgcg cctcgatgag ttccgcgcct gatgaacctc cagaaaatat
    13921 acggcttcag cgagcctttc cgttttacag gttcctcaac aggccggtgg gccgtttgta
    13981 tcatcaatat cagtattcgc aaaaccagat gaatgattgt ttaaactggt gtatttctgc
    14041 ctttatgctt cgtaagtggg gtctgagggc caatggaacg aaaacgtacg ctaaggaaat
    14101 aaccaattgt tataattgat attattcatt cttctctatg aactgaaagc ccgcactaag
    14161 caatgtttta gcctcaaatg acttttttac ctacccaact aacgtaacga tcgcacatca
    14221 ggtcgttttt caaccgcata gtgacacctg cactcacatg cgagaaaaca catatgattt
    14281 tgacttcttg ttttggtgga gagacaatac ccattcatag caggagtaca taatgccaga
    14341 aattgcatcc ctacaacttt tcaaaatact atctgatgaa acccgcctgg gtatcgtgct
    14401 actgctcagg gagatggggg agctgtgcgt atgcgatctc tgcacagcgc tggaacaatc
    14461 acaacccaag acctcccgcc atctggcgat gcttcgggaa agtggcctgt tgctggatcg
    14521 taagcagggg aaatgggttc attatcgctt atccccgcat attccttcct gggctgccct
    14581 ggtgattgag caggcctggt taagtcaaca ggacgacgta caggccatcg cccgtaagct
    14641 ggcatcggcc aactgctctg gcagcggtaa ggctgtttgt atctaaaaat tttgcctgta
    14701 catatatgtt tttacgaata tgaggtgtta aagatgaaaa tgttaacggt gtttgatccg
    14761 gcgatgtgct gcagtaccgg cgtttgtggt tcggatgtcg atcaggtttt ggtcaatttt
    14821 tctgctgatg tgcaatggct gaaagggcgt ggggttcaga tcgaacgtta taacctggcg
    14881 cagcagccta tgagcttcgt tgagaacgaa aaagcgaaag cattccttga ggcttctgga
    14941 gctgaagggc ttccgctgct gttgcttgat ggtgaaacgg tgatggccgg gcgataccca
    15001 aaacgcgctg aactggctcg ctggtttggt ataccgctgg aaaaggtggg tttagcttcc
    15061 accagttgct gtggtggtaa aacttcctgt tgttgagtat gtcaggagga catatgaaat
    15121 tcttagagaa tatcccgtct tacctgtttt tcaccggtaa gggaggtgta ggcaaaactt
    15181 cgatttcctg cgcaacggct atacgtctgg ctgaactggg aaagcgtgtt ctgcttgtca
    15241 gtaccgaccc ggcttccaat gtcggtcagg tattcgatca gactatcggt aacactatcc
    15301 agcccgtgac tgctgtgtct ggtctttcgg ctctggagat tgacccgcag gacgccgccc
    15361 agcaataccg cgccagaatc gttgacccta ttaaaggtct tttgcctgat gacgttgtta
    15421 acagcatcag tgaacagctt tcaggagctt gtacgacaga gatcgctgca ttcgacgagt
    15481 ttactggctt actgactgac gcttctctgc tgacccgctt tgatcacatc atttttgata
    15541 ctgccccaac tggccacact attcgccttc ttcagcttcc cggagcctgg agcagcttca
    15601 tcgaaagtaa cccggatggt gcttcctgtc ttggtccaat ggctgggctg gaaaaacaac
    15661 gcgagcaata tgctcatgcg gttgaggcat tatccgatcc tgaacgaact cgccttgtgc
    15721 tggtcgcgcg attgcaaaaa tcaacactgc aggaagtcgc tcgtactcat gacgaattat
    15781 cagctattgg ccttaaaaat cagtatttag tcattaacgg tgtcctgcct gcgagcgaag
    15841 cagaacgtga tgcactggcc gctgcaatat ggcaacggga gcaagaggcg ctggcaaatc
    15901 ttcctgccgg gttatctgat ttgccgacag acaacttata cctgcagccg ctgaacatgg
    15961 ttggtgtatc cgcattgaaa ggcctgctca acgaacacgc tgagataaca tcgcttcctg
    16021 aacaaagccc acagaacaag ccagagaata tgtcgttgtc tgtcctggtt gatgatatcg
    16081 cccgcagtga acacggtttg attatgctga tgggcaaagg tggtgtgggc aaaaccacaa
    16141 tggctgcggc tatcgccgtc agtctggcgg ataagggttt tgatgtgcat ctcaccacct
    16201 cagatcctgc tgcacatctc agtacaacgc tcaatggcag cctcaaaaat ctgcaggtca
    16261 gccgaatcaa ccctcacgat gaaactgaac gctatcgtca gcatgttctt gagacgaaag
    16321 gcagggatct ggatgaggct gggaaacggc tgctcgaaga ggatttacgt tctccttgca
    16381 cagaagagat tgcggtgttc caggcgtttt cacgcgtaat tcgtgaagct ggcaaacggt
    16441 ttgtggtcat ggatacggca cctaccgggc atacgctatt actgcttgat gctaccgggg
    16501 cttatcaccg tgagattgcc aggaagatgg gggataaagg tcattttacc actccgatga
    16561 tgcagcttca ggaccaggaa cgtaccaaag ttttgctggt cactctgcct gaaaccacac
    16621 ctgtactgga agcggcaaac ctgcagtccg atcttgaacg tgcggggatt catccctggg
    16681 gctggattat caataacagc ctttcgattg cacagacgca atcgccgctg ctttgccagc
    16741 gcgccctaca agagcgtcct caaatcgagg ttgtgaaaaa ccagcatgca agccgcatag
    16801 cgttagtacc ggtaatggct gcagagccca ctggcatcga gaaactcaga gagctggttg
    16861 tttaattttt tttgtatata cagggcggca aagccgtcct gtctggagga tttatgttac
    16921 tggcaggcgc tatttttgtc ctgaccatcg ttttggttat ctggcaaccg aagggattag
    16981 ggatcggctg gagtgcgacg ctgggcgcgg tactggcgct gatctctggc gtagtccatt
    17041 ttggtgatat ccctgtagtg tggaatattg tctggaatgc gacggcgacc tttattgccg
    17101 tgattattat cagccttctg ctcgatgaat cgggcttttt cgaatgggcg gcgctgcacg
    17161 tttcacgttg gggtaacggc cgcgggcgtt tgctgtttac ctatatcgtt ttgctcggcg
    17221 cagcggtggc ggcactgttt gccaacgatg gtgcggcatt gattctgacg ccaattgtta
    17281 tcgccatgct gcttgcatta ggtttcagca aaggcactac gctggcattt gtcatggccg
    17341 ccgggtttat tgccgatacg gccagtctgc cgcttatcgt gtccaacctg gttaacatcg
    17401 tttctgcaga cttctttggg ctgggtttca ctgagtatgc gtcggtaatg gtgccggtgg
    17461 atatcgcagc cattatcgcc acgctggtga tgctgcatct gttcttccgc aaagatattc
    17521 cgccaactta cgacctggct ctcctgaaag caccggcaaa agcgattaaa gatctggcaa
    17581 ccttcagaac cggctggata gtgttgatcc ttcttctggt tggctttttc gtccttgagc
    17641 cgttgggtat cccggtcagt gcgattgctg ctgtaggggc tgtcattctg tttgcggtgg
    17701 cgaagcgagg ccatgccatt aacactggca aagtgcttcg cggtgcgcca tggcagatcg
    17761 tcatattctc tctgggaatg tatctggtgg tctatggtct gcgtaatgcc ggactaacag
    17821 aatacctctc cggtgtgttg aacgtgctgg cagataaagg actttgggcc gcgacgtttg
    17881 gtactggctt cctgacggct ttcctctctt ccatcatgaa caatatgcct accgtgctgg
    17941 ttggtgctct ctctattgat ggcagcactg caacaggcgt tatcaaagag gcgatgattt
    18001 ttgccaacgt gattggctgc gatcttggac cgaaaattac acctattggt agcctggcaa
    18061 cgttgctctg gctgcatgtc ctttcacaga agaacatgac catcacatgg ggatactatt
    18121 tccgcaccgg gatcgtcatg actctgcctg tgctgtttgt aacgctggcc gcgctggcgc
    18181 tacgtctctc tttcactttg taatgagata ctgatatgag caacatcacc atttatcaca
    18241 acccagcctg cggcacgtcg cgtaatacgc tggagatgat ccgcaacagc ggtatcgagc
    18301 cgaccgttat tctttacctt gagactccac cttcacgcga tgagctgctc aaactcattg
    18361 cggatatggg tatttccgtc cgggcgttgc tgcgtaagaa cgtcgagccg tatgaggaac
    18421 tgggtcttgc agaagataaa tttactgacg accagctcat cgactttatg ctacagcatc
    18481 cgattctgat caaccgtccg atcgtagtga cgccactggg aactaaactt tgccgtcctt
    18541 cagaggttgt tctcgatatc cttccagatg cccagaaagc ggctttcacc aaggaagacg
    18601 gtgaaaaagt cgttgatgat tcaggtaaaa gactgaaata aagacgaagg gggcatttgc
    18661 ccccttcatt attacttcgc catttcttcc agcaggtcaa taccaaccgg ctcttcgctc
    18721 tgtagcgctg ttaatgcaat acgctttgca tactgctctt ccacatcaga gatgagaggc
    18781 agctcgcggt tcgccctgat cttcaggaaa ggcgaagacg gttgagcagc tgccaggctg
    18841 ttattaacga cccatgccca cggctcgatg ccagctcggc gtagatcctg ctgcaggtta
    18901 gcggcttcca gtacaggtgt cgtttcggca agcgtcacga taatcacctt cgtcttctcc
    18961 gggtctgctg ctttttcgct atcacctgtc ttcgatgtca gaaagcgaga gaattcggct
    19021 tcatgctgtc gccagaacac actcatgcaa ttgttgaatg cctttacatc actcgtgtcc
    19081 tcaaattttg ctcagattaa cccggctctc atcttccaga attttataaa cagtggaacg
    19141 ggcaatactg agccggcggg caatatctgt tgcaccagtt ccctgctgat gaagtgccag
    19201 tacactattt ctgtcgatga tgcgctttcg gccaaaccgg atacctttca gcctggcctc
    19261 ctgccgtcct tcgttcgtac gctccagaat cctcctgcgt tcggcctggg ctacagctga
    19321 aagaatggtc acaaccattt tccccatttc accgtcggtg ctgatcccgt cgtctatgaa
    19381 tcggaccgcg actccctgag cgtcgaattc ttttatcagt tggatcatat cggcagtgtc
    19441 gcggccaagc cggtcgagtt tcttcaccag gatgacgtca ccttcctcca ccttcattcg
    19501 cagcagatcc agtcctttcc tgtcggtaga actgccggat gctttgtcgg taaatatgcg
    19561 actggctttc acccccgcct ctttaagccc cttgatctga atatcgaggg actgctggct
    19621 tgttgatacc cgtgcgtaac caaaaagtcg cataaaaatg tatcctaaat caaatatcgg
    19681 acagtgggtg tctgttataa caaaaaatcg atttaataga cacctagaca acaccatttt
    19741 agtgtgtccg agaatttata atatttcgga cggttgcgaa attgttaatt catgaccatc
    19801 aggcagggag gccggtatgc ccgtcgattt tctgaccact gagcaggaac tgaattatgg
    19861 tcgctatgtt gcagaaccca atgacgtgca gctggcgcgc tattttcatc ttgatgagcg
    19921 ggatcttgcc ttcattaacc agcggcgggg aaggcataac cggctgggaa ttgcgcttca
    19981 gctcaccacc gcccgttttc tgggcacctt tctgacagac ttaacccggg ttctgccagg
    20041 tgttcagcaa tttgtcgcgg tgcagcttaa tattcgccgt ccggaagtcc ttacccgcta
    20101 cgcagaacgg gttaccaccc tcagagagca tactgcgctg attaaggaat attacggtta
    20161 ccatgaattt ggtgatttcc cctggtcttt ccgcctgaag cgcctgctgt acacccgcgc
    20221 atggctcagt aatgagcgac ccggccttat gtttgatttt gccaccgcgt ggctgcttca
    20281 gaataaggtc ctgctgcccg gagcaaccac acttgtacgt ctcgtcagtg aaatacgcga
    20341 acgggcaaat cagcggctgt ggaagaaact ggccgcgttg ccggacagct ggcagaccgc
    20401 ccgcgtgacg gagcttctgg acattcctga ggggcagcgt acttcaccgc tggagcaact
    20461 gaaaaaggga ccggtcaccg tcagcggccc ggcatttacc gaagcgctgg agcggtatat
    20521 ccggctgcga aacctggaat tttcccgact gaattttacc ggtctgcctg ctatacaact
    20581 gcgtaatttg gcccgttacg caggcatggc gtcggtaaaa tatatcgcgc gaatgccaca
    20641 gcagagaaaa ctggccgtac tcacagcatt cgttaaagcg caggagactg cggcgctgga
    20701 tgaggccgtt gatgtgctcg atatgctgat actggatatc actcgtgcgg cgaagaaaac
    20761 ggggcagaaa aaacggctca ggacgcttaa agatcttgat cgtgctgcgc taatattggc
    20821 gcgggcatgt tcattgttgc tggatgaaca ggctgacgat gctgaactga gggagaccat
    20881 attcaacagc ataccgaaaa gcaggctggc agaatccgtc agcaaggtaa atgagctggc
    20941 ccggcctcag aacaacaatt tccatgacga aatggtggag cagtacgggc gggtaaagcg
    21001 ctttcttccg gcggtattgc gcgacctgca tttccaggca gcgccagccg gagaacatac
    21061 gttgtccgcc attcattatc tgaccgaact gaacggctcg aaaaagcgca tcctggacaa
    21121 tgcgcctgaa catattatta ccggcccctg gaaacgcctg gtatacgatg cggagggccg
    21181 gatacagcgt gccggttact cgctttgtct gctggagcgc cttcaggatg cactacgtcg
    21241 aagggacatc tggctcgaaa acagcgatcg ctggggaaat ccccgcgaga agctgttgca
    21301 gggggaagaa tggcaggctc agcgggtccc cgtttgccgg gcgctgggac atcccactga
    21361 tggacataaa ggcgtgcaac agttggcggt ccagctagat gaaacctgga aaaccgtcgc
    21421 atcccgcttt gaaggaaatg cggaggttca tatttgccat gacggtaaac atccttccct
    21481 gactatcagc agcctggaga aactggagga gccaacatcg ttgcatcgtc tcaacagtcg
    21541 ggtaaggctg ctactcccgc cagtagattt gacggaactg ttgcttgaaa tagatgccag
    21601 aacgggattt acacgtgagt ttacgcatgt cagtgaatcc ggggcccggg cacaggatct
    21661 gcacatcagc ctgtgcgcgg tcctgatggc agaggcctgc aatatcgggc tggaaccgct
    21721 gataaagcac aatataccgg cgctgacgcg ccaccggctt agctgggtaa aacagaatta
    21781 cctccgggca gaaacgctgg tcagcgccaa tgcccgcctg gttgattttc agtccacact
    21841 ggagcttgct ggccgctggg gtggtggcga agtggcttca gctgatggca tgcgctttgt
    21901 cacgccggtg aaaaccgtca attcaggacc taacagaaaa tattttggtt ccggacgtgg
    21961 catcacctgg tacaacttcg tctctgatca gtactctgga ttccacggca tcgttgtccc
    22021 cggcacatta cgagattcca tttttgtgct ggaaggcctt ctggagcagc agacagggct
    22081 gaatccggtt gagatcatga cagacacagc cggtaccagc gacattattt ttggcctctt
    22141 ctggctgctg ggataccagt tttccccccg gcttgccgat gccggtgaag cggtattctg
    22201 gcgagtggat aaatcggcaa attacggtgc actggacgaa ctggcacgtg gttgtgccga
    22261 tctgtcgaaa gccgaggatc agtgggatga gatgatgcga accgccggtt cgctgaaact
    22321 gggcaccatt catgcttcag aactcattcg ctctttgctg aaaagctcgc gcccatcagg
    22381 gctggcacag gcgatcatgg aagtggggcg cgtcaacaag acgctgtacc ttcttaatta
    22441 tattgatgat gaggattatc gtcggcggat cctgacgcag ctaaaccggg gggaaggccg
    22501 ccatgctgtg gcgagggcga tctgctacgg gcagcgcggt gagatcagaa agcgctatcg
    22561 tgaaggtcag gaagatcagc tgggggcact gggcctggtc actaacgcag tggtactgtg
    22621 gaacacactt tatatgcagg aagccctgag ctggatacgc agtaatggag aagaaatcgg
    22681 ggttgaagat atcgcccggt tgtccccact gatgcacggg catatcaata tgctggggca
    22741 ttatacgttt acgctaccgg aggatatttt gaagggggaa ctgagagaac taaatttcaa
    22801 tttaaacaat gaattaactt cttagcgtac gttttcgttc cattggccct caaaccccta
    22861 agtttgctgt cgcgccgtca gtgcccaggc tattctggcc agcttgtttg ccagagcaca
    22921 ggtgacgaca aagttgcttt ttcgacacaa caactccctg acccagtcgg ccaacttgcc
    22981 agactggtgt tccagttttt gtatgaatac cctggcacac tgaaccaaca aagttcggat
    23041 ctttttgttg ccccgcttgc taatccctaa caatgtcgtc cgacctcccg tgctgtactg
    23101 tcggggtacc agccctgttg ccgccgcaaa gtcacggctg ctggcgtact gcttcccgtc
    23161 gccaatctca gttgaaatag tactggcagt cagcgttcca acgcagggaa tactcagcaa
    23221 gcgctgtcca acctcatctt cgtccaactt tcgtttcaac tgagattcca gatctttaat
    23281 ctgctcaaca agatagtgat aatgctgttg taatttcagc agtaactggc tgagataaag
    23341 aggcaaacta ctgtcctcaa gaagggtact cagtcgacta ataacggcag cacctcgcgg
    23401 aacgctgata ccaaattcca gcagaaaagc atgcatctga ttagttgttt tcaccttatc
    23461 ctgaaccagg gattcacgga cacgatgcag agctcgcatt gcctgctgag attcggttct
    23521 gggctgcacg aaacgcatag atggacgtga tgctgcttca cagatagctt cagcatcaac
    23581 gaagtcattt ttgttgcttt taacgaatgg gcggacaaat tgcggtgata tcagctttgg
    23641 aaaatgccct aactctgcca gcttgcgtgc cataaagtga gaaccgccac aggcttccat
    23701 cgcgatggtt gttgctgggc atgtcgccag aaattcgatt agctttggtc gggtgaattt
    23761 tttacggtaa acggccttcc cacgatgatc ctgacaatga atatggaaag agttcttacc
    23821 cagatcgata ccaataagcg caatgttttc catgatggtt ctccgaatga aagcctgtcc
    23881 tcagcatagt actgggaagg agggagtgac catctcatta aataaagcac gctaagcgtg
    23941 cgtggaggct ggcacccagc ggtacagcgt cggaatggac acgccgaggt tcttggccac
    24001 gtccttgggc ggcaccccgc tggccagcag cttcttggcc gactcgatct tgctgtcggt
    24061 catcttcggc ttgcggccgc ctttgcggcc gagctgcttg gcgacttcca gcccggcgcg
    24121 ggtgcgctcg acggtcagct cgcgctccat ttcggcaagg ctcgccatga cgtggaagaa
    24181 gaaccgcccg gatggtgtgc cggtgtcgat ggagtcggtg aggctcctga actggacacc
    24241 gtgcttgtgc agatcgccga ccagatcgac cagttgcttg accgaccggc ccagccggtc
    24301 gagcttccag acgaccaaag tatcgccttc gcgcagcatt tcgagcgtct tggccaagcc
    24361 aggccggtct gcccgcgtgc cactcacctt gtcctcgaag acctttttac atccggcctt
    24421 gctcaaggct tcgcgttgca gctccaggtt ctgatcctgc gtcgagacgc gcgcatagcc
    24481 aatcaacatg gcttgtctcg cgcccggtcg atgcgttcct gcatcgcctg catcacttct
    24541 tcgtgggtgt acgatctggc gttggcgtcg gtggcttgcc gcagggcttc ctcaacctcg
    24601 cgcgtcatcc gctcgtaatc ctccggccac agcgcttgct ccatgcgcag cgacgcctga
    24661 cccagcaggt gcagcaggct gaacagccgc atgtcgttgg tggcgacgat gcgctcccga
    24721 atctgctcct gaatagcttc gctagcccga tgcgcttgtg gtgtggcagt cccctcgtag
    24781 tcagcgggga attccgcttc ctcggcaatc cttgcccagg cgctggccag cgcctcgatg
    24841 gttgacgtgc tcatttccgc cgctcctgtg ctctttggcg aatcaaccgg ccaaggggcc
    24901 tcgacgcgaa aaccagcagc atcacgccta tcggatacca ggtcgagaag accaccaagg
    24961 catcgaaggc tggccgtccg gtgttggtag gcagtacggc ggtcacagcc atcaacccgc
    25021 cgaccgtcca gatgatgcgc cacacgtagg gcatcacgcg gggcacgtag ccgtcatcga
    25081 aagcggtctg gtagtagcgg cgcaggccgc gctcggcaag cgcctggcgc tgccgctccg
    25141 acagcgcatc cgtccggcca taccagcgcc ggaatggtgg acagcgcagc agcaaagggg
    25201 tgaagaggat catcaccgcc acgatcgcga caccccacgc catgacggcg ccggcatcgg
    25261 gccgcttggc gttctcgatc acgggcgcga agacgcccgg agcaccgatc atccagaaca
    25321 gcgcaatgtg ctgatggaag gagagcttca tttgctcatc cacttgcgca gcaggcgctt
    25381 tttcagggag gcgcgttctt gcgggttgcg tcccttgtga ttggcgatgc gatccgccgt
    25441 ggcggcctgg cgcttgacgg gccagtagga gcggccatcc ttgcccatcg accagacgct
    25501 gctggcctgg ttttccagca ggggcagatg ggcgctcagg gcttcgggcg acgcgctggt
    25561 cagcgccgtg cgctcacggg tgcgccagcg ctgatgccag agcttcttgt cctcgcgctc
    25621 gctgccgcag gtcgtgtgcc cgacgatggg tgttttgcgg cggctgcggc tcataacgta
    25681 gtggtctcca agaacattca ggactgatcc caggcgtcga tggtcaagac ctgatcggca
    25741 ggacaggcgg ctacgcggtc gggaactgga tggtgttcag tctcatgccg accccattcg
    25801 attgatcgcg tcgcttgcgg cacgctgcga cgcaaggagg tttgcgacct ggtttagcag
    25861 ccgtgtccgc tgcatgtctg ttacctatct ccccgaccgc tcattggacc aactccagag
    25921 attgggctct atcgctcagc caatacgaaa ccggcattgg ctgatgccac aaccgagacg
    25981 aacacaaatg gctcggtacc tgtatttcgc gccccgtgca cttggcccgg tcttgccacg
    26041 gctatctcac cttccctgag ggcacgaaca atcccattgc cctgaaagta atcagccatt
    26101 cccgacaaaa cagtccacgt gtcttggccg tgaggatgaa tgtgagccgc aatttcctgc
    26161 ccgggatgga catgccaaac cacgataatt gagtctcggg tttcaagcac aacggaacga
    26221 ataggctcgc cttcggacgg ctgaacatac tcggctacag aaaatattct cgattcaaca
    26281 gtcatcggag atccctcttt cacagtgccc ccagacaggc tggatatgaa ttctaactcg
    26341 aatttgaacg ggaggctggt cgtgcggtcg tgcagttgcc gatgagcgtg tcggctgctg
    26401 cctccttgcc caccagcgaa ctcacgtccg ttgcggccat ccagaaggtc ttgcccgagc
    26461 gcggctcata ggtcgcggga tcgaacacgc cagaggggcc gaacatcggc ggcttgattg
    26521 gtcatggctc catgcctttg tcgttacggt cttcatcgtc ggcatcctga cgcacggcgg
    26581 gcaattgctg gagcaacgcc ggcagccatt cctgtaccgt ctcccacacc acatcgaggt
    26641 tgatgtcgaa atagccgtga gccatgcgat tacgcatatt gcgcatgctg cgccacggca
    26701 cgtcggcatg cg
//
