LOCUS       NZ_CP054989             6817 bp    DNA     circular CON 02-MAY-2024
DEFINITION  Klebsiella pneumoniae strain STIN_90 plasmid unnamed5, complete
            sequence.
ACCESSION   NZ_CP054989
VERSION     NZ_CP054989.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN13925547
            Assembly: GCF_022353705.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6817)
  AUTHORS   Che,Y., Xu,X., Yang,Y., Brinda,K., Hanage,W., Yang,C. and Zhang,T.
  TITLE     High-resolution genomic surveillance elucidates a multilayered
            hierarchical transfer of resistance between WWTP- and
            human/animal-associated bacteria
  JOURNAL   Microbiome 10 (1), 16 (2022)
   PUBMED   35078531
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6817)
  AUTHORS   Che,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2020) Civil Engineering, The University of Hong
            Kong, Pokfulam Road, Hong Kong 000000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: "Other" v. Unicycler
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology :: Illumina; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022353705.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 04:59:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,770
            CDSs (total)                      :: 5,646
            Genes (coding)                    :: 5,488
            CDSs (with protein)               :: 5,488
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 69 of 158
            Pseudo Genes (incomplete)         :: 96 of 158
            Pseudo Genes (internal stop)      :: 39 of 158
            Pseudo Genes (multiple problems)  :: 35 of 158
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054989.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6817
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="STIN_90"
                     /isolation_source="Shatin WWTPs_90 WWTPs influent"
                     /db_xref="taxon:573"
                     /plasmid="unnamed5"
                     /geo_loc_name="Hong Kong"
                     /lat_lon="22.4 N 114.2 E"
                     /collection_date="2018-12"
     gene            join(6731..6817,1..543)
                     /locus_tag="HUZ59_RS28710"
                     /old_locus_tag="HUZ59_28660"
     CDS             join(6731..6817,1..543)
                     /locus_tag="HUZ59_RS28710"
                     /old_locus_tag="HUZ59_28660"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_140430500.1"
                     /translation="MRHIFFLLYFFCISTIASNELKINNMPIELIFNDGSSAKISSCTD
                     LQNQMSLGKKIESIPNISDPDYNDIKNKIFICRMQNYISNHRMTRIKDSLSIHDVLSNF
                     PATAAYFISQEEMDKVSREYSNKTILEYTPDLIIDKNKAISQKKYTSYSLPEYYHFKNS
                     DGDEIKIVILAGHSIGGTASSRSYWRIDDDHSHPWTVTELDENSFL"
                     /name="hypothetical protein"
     gene            complement(607..1368)
                     /locus_tag="HUZ59_RS28715"
                     /old_locus_tag="HUZ59_28665"
     CDS             complement(607..1368)
                     /locus_tag="HUZ59_RS28715"
                     /old_locus_tag="HUZ59_28665"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_224728059.1"
                     /translation="MPGFNYGGYGDGTGWSSERGDGPAPGGGSHGNSGRDDHRGESGYG
                     YPGHNGISGPVSLRTTDSYDGDTMSGYINNLINHEGFKNTMYRDTEGNITVGIGHLLSS
                     PEMAAGLPFNRTRITHGHGDEMEHEFSVSREDITSSFNALRDNPTAISGIHISNDAVIG
                     LAISDVESTISGLKGLYSDFDSFPRSAKTALVDMGFNVGVGKLRSDFPNFNNAVNKKDW
                     NTAADESHRTKIGEGRNNDTKAQFQQAANGN"
                     /name="hypothetical protein"
     gene            1627..2064
                     /locus_tag="HUZ59_RS28720"
                     /old_locus_tag="HUZ59_28670"
     CDS             1627..2064
                     /locus_tag="HUZ59_RS28720"
                     /old_locus_tag="HUZ59_28670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="WP_170936219.1"
                     /translation="MGHCHFMAWHTLQDALKMTGRSRSQFYRDMRAGLVSYRTSQDGRR
                     EFETSELIRAYGELKRNETPERHTAGQAEKPHNQQTERILREVNELKQCLTLMLEDKQA
                     QDTERRRQEAEREQLQNEIVQLRQALEQEKKRGFWSRLFGR"
                     /name="entry exclusion protein 1"
     gene            2145..2573
                     /locus_tag="HUZ59_RS28725"
                     /old_locus_tag="HUZ59_28675"
     CDS             2145..2573
                     /locus_tag="HUZ59_RS28725"
                     /old_locus_tag="HUZ59_28675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_094307660.1"
                     /translation="MKRSGGTRYMYLSALITVTAALTACTPKTSLEQHTRHYVYASDDG
                     FDPNFYTKKADTTRMMIPFFQQFREMGVKDKAAGVSAEKAQQRIKEFHSEEFLQSLRTT
                     TNFAGRKYTNSDTPSPEKMKLLADTISAIYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            2798..3007
                     /locus_tag="HUZ59_RS28730"
                     /old_locus_tag="HUZ59_28680"
     CDS             2798..3007
                     /locus_tag="HUZ59_RS28730"
                     /old_locus_tag="HUZ59_28680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgH/BhsA/McbA-like domain containing protein"
                     /protein_id="WP_009310047.1"
                     /translation="MKSIKTFVAVAALSMMSFGAFAQSVSATASTLDRAEAKIAAQAAE
                     QGASYKITSAQFNNRVHMTAELTK"
                     /name="YdgH/BhsA/McbA-like domain containing protein"
     gene            complement(3630..3863)
                     /locus_tag="HUZ59_RS28735"
                     /old_locus_tag="HUZ59_28685"
     CDS             complement(3630..3863)
                     /locus_tag="HUZ59_RS28735"
                     /old_locus_tag="HUZ59_28685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021534848.1"
                     /translation="MTELEKHLLNALEQLQQDYMQRLNEWESAFVELQKMFSLTQRDNA
                     MLNERVMKLSQQVQHLSERTERLSQLYSENRR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(3870..4400)
                     /locus_tag="HUZ59_RS28740"
                     /old_locus_tag="HUZ59_28690"
     CDS             complement(3870..4400)
                     /locus_tag="HUZ59_RS28740"
                     /old_locus_tag="HUZ59_28690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001673158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_001314441.1"
                     /translation="MSNLLQTGAEFEKKLKERAESTEKMLNDEFRKLEESVNRELTSNE
                     SLIRNAINDHTTALKELLERYQKTTVSTMDTHWQTVLKMSVKRWLWLIIVSVLMFATTG
                     SLLWYQGMKINVNMNILREQKESLEKLNAKTWGVRYHEDSNGRFLVLPKGMKAETNWTE
                     DNGKLNAVRLVQE"
                     /name="MbeB family mobilization protein"
     gene            complement(<4438..5136)
                     /locus_tag="HUZ59_RS28905"
                     /old_locus_tag="HUZ59_28695"
                     /pseudo=""
     CDS             complement(<4438..5136)
                     /locus_tag="HUZ59_RS28905"
                     /old_locus_tag="HUZ59_28695"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(5078..5401)
                     /locus_tag="HUZ59_RS28750"
                     /old_locus_tag="HUZ59_28700"
     CDS             complement(5078..5401)
                     /locus_tag="HUZ59_RS28750"
                     /old_locus_tag="HUZ59_28700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_000956000.1"
                     /translation="MLTIRVTDDEHARLLERCEGKQLAVWMRRVCLGEPVARSGKLPTL
                     APPLLRQLAAIGNNLNQTARKVNSGQWSSGDRVQVVAALMAIGDELRRLRLAVREQGTR
                     DDS"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            5466..5657
                     /locus_tag="HUZ59_RS28755"
                     /old_locus_tag="HUZ59_28705"
     CDS             5466..5657
                     /locus_tag="HUZ59_RS28755"
                     /old_locus_tag="HUZ59_28705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165974.1"
                     /translation="MTKQEKTALNMARFIRGQTLTLLEKLNELDADEQADICESLHDHA
                     DELYRSCLARFGDDGENL"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            6325..6438
                     /locus_tag="HUZ59_RS28760"
     CDS             6325..6438
                     /locus_tag="HUZ59_RS28760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071821494.1"
                     /translation="MHEPPVQPDRCALSGNYRLESNPVRHDLTPLAAATGN"
                     /name="replication initiation protein"
     gene            complement(6478..6663)
                     /locus_tag="HUZ59_RS28765"
                     /old_locus_tag="HUZ59_28710"
     CDS             complement(6478..6663)
                     /locus_tag="HUZ59_RS28765"
                     /old_locus_tag="HUZ59_28710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005421809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_094307661.1"
                     /translation="MSKKDAKILLRSFFSARNLLLANKKTTATNGGLFAGSRATNSFSE
                     GNWLGGAQSPKPVFSV"
                     /name="hypothetical protein"
     Typing          complement(5743..5824)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="96.386"
                     /coverage="100.0"
                     /evalue="1.35e-30"
     Typing          5841..6397
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.238"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(3527..5088)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="95.777"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttaattttta atgacgggag cagtgcaaaa atatcatctt gcactgacct tcagaatcag
       61 atgtcactag gaaaaaaaat agagtcaata cctaacattt cagacccaga ttacaatgat
      121 ataaaaaata aaatatttat atgcaggatg caaaattaca tatcaaatca tcgaatgacg
      181 agaatcaaag actcattatc aatacatgac gttttgagta attttccagc aacagcggca
      241 tattttataa gtcaagaaga aatggataaa gtttctcgtg aatacagcaa caagacaatt
      301 ttagaataca caccggatct tattattgat aaaaataaag caatatcaca aaaaaaatac
      361 acaagctact cactgcctga atattatcac tttaaaaata gtgatggtga tgaaataaaa
      421 attgttattt tagcagggca ttcaattggt ggtacagcta gctcacgctc atactggcgt
      481 atagatgatg atcattcaca cccctggaca gtcactgaac ttgatgaaaa tagtttctta
      541 taattcaatt aattaccacc tcataaagag gtggtatagg catgaaatat gtagaatcct
      601 ttatgcttag ttaccattag ctgcttgttg gaactgagct ttcgtatcat tatttcggcc
      661 ttcacctatc ttagttcgat gagactcatc agccgcagta ttccaatctt tcttatttac
      721 agcattatta aagtttggaa agtccgatcg taatttacca actcccacat tgaaccccat
      781 atcaactaat gcggtttttg ctgaacgagg gaaactatca aaatcagaat aaagcccttt
      841 taatcctgaa attgtcgatt ctacatcgct aatagcaaga ccaattactg catcgtttga
      901 aatgtgaata ccagaaatag ctgtaggatt atctctcaat gcattaaatg aagatgtaat
      961 atcttcccgc gatacagaaa actcatgttc catttcatca ccatgtccat gtgtaattct
     1021 agttcggtta aacggtaatc cagccgccat ctccggtgat gaaagcaagt gaccaatacc
     1081 gacagttatg ttcccttcgg tatccctata cattgtattt ttaaaacctt catgattgat
     1141 taagttgtta atataacctg acatagtatc accatcataa ctatctgttg tcctgagact
     1201 cacaggccca gatatcccat tgtgaccagg ataaccataa ccactttcac cacgatgatc
     1261 gtctcgacca ctattcccat gagaaccgcc tcctggagcc ggaccatcac cacgttcaga
     1321 actccagcca gtaccgtcac catatccacc ataattaaat ccaggcataa ctaactcctc
     1381 tttgacttgt aaaacaaacc gttaaaaaca aatactgtat atataactac tggttttata
     1441 tacagcttaa aaattacgcc gctgcgtttt ccctgtcaac cctgtggatt ttcgtttttg
     1501 tgaaaacgat caaaaaacag ccaaccacac cacgtgctat tcccgcccga tgccacaaaa
     1561 accagcacaa acattaccgt tctccggcct cagtatgttt tactgaaacc atgatatgag
     1621 acaccaatgg gacactgtca cttcatggca tggcacacac tccaggacgc actgaaaatg
     1681 acgggcagat cgcgttcaca gttttaccgt gatatgcgcg caggccttgt cagttaccgt
     1741 acgagccagg acggacgacg ggagtttgaa accagtgaac tgatccgggc atacggcgaa
     1801 ttaaagcgga atgagacacc agaaaggcac actgcgggac aggcagaaaa acctcataat
     1861 cagcagacag aacgcattct ccgggaggtg aacgagctga aacaatgcct gacgctgatg
     1921 cttgaggata aacaagccca ggatacggag cgccggcgcc aggaagcaga acgggaacaa
     1981 ctacagaatg agatagtcca gctcaggcag gcgctggagc aggaaaagaa acggggattc
     2041 tggtctaggt tgttcggtcg ctgaacgcgc tcagagactg atgataagat agccatcaga
     2101 taataactca ccgaaaataa atactttaag gtaaggagac tcgcatgaaa cgttctggcg
     2161 gcacacgcta tatgtatctt agcgccctga taactgtgac agcagccctc acagcctgta
     2221 ccccaaaaac cagcctggaa caacataccc ggcattatgt ttatgcttca gatgatgggt
     2281 ttgatcctaa cttctacacc aagaaagctg acaccacacg gatgatgatt ccgttctttc
     2341 agcagttccg ggagatgggg gtgaaagaca aagcagccgg agtatcagca gaaaaggcac
     2401 agcaacgcat aaaagaattc cactctgaag aattccttca gtcactgaga accacaacca
     2461 actttgcggg cagaaaatac acgaacagtg atacgccatc accggaaaaa atgaagctgc
     2521 tggctgacac gatttctgcg atttatctcg atggctacga gggaagacag taagtggatt
     2581 taccataatc ccttaattga acgaaccctc aaggctattc atcctgcccc taaatcagag
     2641 tctcacacct ggttttgatt cgctcaattt ttattctatt tttttgaatg atatccgcaa
     2701 attgtttcga ttttaatcag ctcatggtcg tcctatcatt tatcacatca gggcaacaac
     2761 gcccgataca gaacaaaatt acttaaggaa tacgaccatg aaatccatca aaactttcgt
     2821 tgcagttgct gctctatcca tgatgtcttt cggtgccttt gctcagagcg tcagcgctac
     2881 cgcctccacc ctggatcgtg ctgaagcaaa aattgccgca caggctgctg aacagggtgc
     2941 gtcatacaaa atcaccagcg ctcagttcaa taaccgtgtc cacatgacgg ctgaactgac
     3001 caaataagat ggtcgcagat ggagctgccg aacaggtcgc cgggaggcgg cccgtttcgc
     3061 cactaaacag gaaaaccctc aagccccttc tggggccttt ttgcgtctgt tatttaacat
     3121 aaaggcatga ttgtacgcac cgctgaaacg cgttcggtgc gatcacggca gcagacaggt
     3181 aaaaatggca acaaaccacc cgaaaaactg ccgcgatcgc ccccgataaa ttttaaccac
     3241 atgcatagct atgcagccat gtgaatcacg caggaattgc cagccagaga ctgctgaaac
     3301 ggattttttt catactttcg gaaaggcaga agacggaacc ggagcggaaa aacagaaatt
     3361 caggggaatg agcgcgatct ggcaataacg gcaaaacaca gcaacaaaga cacaccagaa
     3421 tcgcgcccat atgcgtttta gtgcgttccc ggtgccccga accaaccatt atcccaaaaa
     3481 atgcaccgga aacacgctga caacatttta gcctgtctct ggttaccatc ccagcgaagg
     3541 gccatccagt gtccgttcct gtatttccgg ctggcgctca cgctccaggg ataactcatg
     3601 ttcgcgttcc tgtatcagcc gttcgtccct tatctcctgt tctcgctgta taactggctc
     3661 aagcgttctg tccgctcgct caagtgctgc acctgctgac tcaacttcat gacccgctcg
     3721 ttcagcatcg cgttgtcccg ttgcgtaagc gaaaacattt tctgcaattc cacgaaggcg
     3781 ctctcccatt cgttcagccg ctgcatatag tcctgttgca gttgctctaa tgcgttcagc
     3841 aaatgttttt ccagctccgt catgctctgt cactcctgta ccaatctcac tgcgttcagt
     3901 ttgccgttgt cctccgtcca gttcgtttcg gctttcatcc ccttcggcaa caccagaaaa
     3961 cgcccgttgc tgtcctcgtg ataacgcacg ccccatgtct tcgcgttcag cttctccaga
     4021 ctctctttct gctcgcggag aatattcatg tttacgttta tcttcatgcc ctgataccac
     4081 agcagactcc cggtcgtggc aaacatcagc actgagacga taatcagcca cagccagcgt
     4141 ttcacgctca ttttcagtac ggtttgccaa tgtgtatcca tcgtgctgac ggtcgttttc
     4201 tgatatctct ccagcagttc tttcagggct gttgtatggt cgttgatagc gttcctgatt
     4261 aaagattcgt ttgaggtcag ttccctgttt acagattctt cgagcttcct gaactcgtcg
     4321 ttcagcattt tctctgtaga ttcggctctc tctttcagct ttttctcgaa ctccgcgccc
     4381 gtctgtaaaa gattgctcat aaaacgctcc tttcagtctg atattcttcc cgccgttcgg
     4441 gtctgcaatg cttatactgc ttcgcgtcac cctgaccact tcaagccccg cctccgtgag
     4501 cgcctgaatt acatcctgac ggccttttat ctccccgaca tgataaagag cgtctatccc
     4561 gcgtgtgacg ctctctgcaa gcgcctgttt cgtttccggc aggttatcag ggagagtcag
     4621 tatccggcgg ttctccgggg cgttggggtc atgcagcccg taatggtgat taaccagcgt
     4681 ctgccaggca tcaattctcg gcctgtctgc ccggtcgtag tacggctgga ggcgttttcc
     4741 gctctgtagc tccatgttcg gaatgacaaa attcagctca agccgtccct tgtcctggtg
     4801 ctccacccac aggatgctgt actgattttt ttcgagaccg ggcatcagta cacgctcaaa
     4861 gctcgccatc actttttcac gtcctcccgg cggcagctcc ttctccgcga acgacagaac
     4921 acctgacgtg tatttcttcg caaatggcgt ggcatcgatg agttcccgga cttcttccgg
     4981 attaccctga agcaccgttg ccccttcccg gttacgctcc cttcccagca ggtaatcaac
     5041 cggaccactg ccaccacctt ttcccctggc atgaaattta actatcatcc cgcgtcccct
     5101 gttccctgac ggccagacgc agccggcgca gctcatcccc gatggccatc agtgcggcca
     5161 ctacctgaac ccggtcaccg gaagaccact gtccgctgtt caccttcctc gctgtctgat
     5221 tcaggttatt cccgatggcg gccagctgac gcagtaacgg cggtgccagt gtcggcagct
     5281 tcccggaacg ggcaaccggc tcccccaggc agacccgccg catccatacc gccagttgtt
     5341 taccctcaca gcgttccagt aaccgggcat gttcatcatc agtaacccgt atcgtgagca
     5401 tcctctcgcg tttcatcggt atcattaccc ccatgaacag aaatccccct tacacggagg
     5461 catcagtgac taaacaggaa aaaaccgccc ttaacatggc ccgcttcatc agaggccaga
     5521 cattaacgct gctggagaaa ctcaacgaac tggacgcgga tgaacaggca gatatctgtg
     5581 aatcgcttca cgaccacgcc gatgagcttt accgcagctg cctcgcacgt ttcggggatg
     5641 acggtgaaaa cctctgacac atgcagctcc cggagacggt cacagcttgt ctgtgagcgg
     5701 atgccgggag ccgacaagcc cgtcagggcg cgtcagcggg ttttagcggg tgtcggggcg
     5761 cagccatgac ccagtcacgt ggcgatagcg gagtgtatac tggcttactt atgcggtatc
     5821 agtgcgaatt gtatgaaaag tgcaccatgc agggtgtgaa atgccgcaca gatgcgtaag
     5881 gagaaaatgc agcttccggc gctcttccgc ttcctcgctc actgactcgc tgcgctcggt
     5941 cgttcggctg cggcgagcgg ttctgactca cacaaaaacg gtagcacggt tatccacaga
     6001 atcaggggat aaggccggaa agaacatgtg agcaaaagac cagtgcagga agaaggccac
     6061 gccgctggcg tttttccata ggctccgccc ccctgacgag catcacaaaa tcgacactca
     6121 agtcagaggt ggcgaaaccc gacaggacta taaagatacc aggcgtttcc ccctggaagc
     6181 tccctcgtgc gctctcctgt tccgaccctg ccacttaccg gatacctgtc cgcctttctc
     6241 ccttcgggaa gcgtggcgct ttctcatagc tcacgctgtt ggtatctcgg cttggtgtag
     6301 gtcgttcgct ccaagctggg ctgtatgcac gaaccccccg ttcagcccga ccgctgcgcc
     6361 ttatccggta actatcgtct cgagtccaac ccggtaagac acgacttaac gccactggca
     6421 gcagccactg gtaactgatt tagaggagtt ggtcttgaag ttatgaacca gttaaggcta
     6481 aactgaaaag acaggttttg gtgactgcgc tcctccaagc cagttacctt cggaaaaaga
     6541 gttggtagct cttgatccgg caaacaaacc accgttggta gcggtggttt ttttgtttgc
     6601 aagcagcaga ttacgcgcag aaaaaaagga tctcaagagg atcttggcat cttttttact
     6661 caaaatactt tcctgtttaa atacattcag tacaaaataa attaacaact aatgtaggag
     6721 aaccctaagt atgcgtcaca tattcttttt gctttatttt ttctgcatat caacaatagc
     6781 ttcaaatgaa ttaaaaatta acaacatgcc tatagag
//
