LOCUS       NZ_CP054778            15931 bp    DNA     circular CON 16-MAY-2024
DEFINITION  Klebsiella pneumoniae strain KP20194a2 plasmid pKP20194a2-p4,
            complete sequence.
ACCESSION   NZ_CP054778
VERSION     NZ_CP054778.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15186438
            Assembly: GCF_013349065.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 15931)
  AUTHORS   Hu,L.M., Zhang,X.T., Zeng,X., Chen,Y., Liu,L. and Li,G.Q.
  TITLE     Genomic Characterization of a Carbapenemase-Producing, Extensively
            Drug-Resistant Klebsiella michiganensis Strain from a Renal Abscess
            Patient
  JOURNAL   Microbiol Resour Announc 11 (12), e0082522 (2022)
   PUBMED   36321904
REFERENCE   2  (bases 1 to 15931)
  AUTHORS   Zhang,X., Ouyang,J., He,W., Zeng,T., Liu,B., Jiang,H., Zhang,Y.,
            Zhou,L., Zhou,H., Liu,Z. and Liu,L.
  TITLE     Co-occurrence of Rapid Gene Gain and Loss in an Interhospital
            Outbreak of Carbapenem-Resistant Hypervirulent ST11-K64 Klebsiella
            pneumoniae
  JOURNAL   Front Microbiol 11, 579618 (2020)
   PUBMED   33281772
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 15931)
  AUTHORS   Zhang,X.T. and Liu,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2020) Clinical Research institute, The Second
            Affiliated Hospital, University of South China, 35 Libration Ave.,
            Hengyang 421001, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 23-JAN-2020
            Assembly Method                   :: SPAdes v. 3.14
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013349065.1-RS_2024_05_16
            Annotation Date                   :: 05/16/2024 02:37:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,917
            CDSs (total)                      :: 5,795
            Genes (coding)                    :: 5,614
            CDSs (with protein)               :: 5,614
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 181
            CDSs (without protein)            :: 181
            Pseudo Genes (ambiguous residues) :: 0 of 181
            Pseudo Genes (frameshifted)       :: 70 of 181
            Pseudo Genes (incomplete)         :: 119 of 181
            Pseudo Genes (internal stop)      :: 24 of 181
            Pseudo Genes (multiple problems)  :: 32 of 181
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054778.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..15931
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP20194a2"
                     /serotype="ST11-K64"
                     /isolation_source="bed sheets"
                     /db_xref="taxon:573"
                     /plasmid="pKP20194a2-p4"
                     /geo_loc_name="China: Hunan"
                     /lat_lon="27.69 N 111.66 E"
                     /collection_date="2019-04-12"
                     /collected_by="Xiaotuan Zhang"
     gene            join(15843..15931,1..643)
                     /gene="mobC"
                     /locus_tag="HUR99_RS29245"
                     /old_locus_tag="HUR99_29250"
     CDS             join(15843..15931,1..643)
                     /gene="mobC"
                     /locus_tag="HUR99_RS29245"
                     /old_locus_tag="HUR99_29250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            650..1180
                     /locus_tag="HUR99_RS29250"
                     /old_locus_tag="HUR99_29255"
     CDS             650..1180
                     /locus_tag="HUR99_RS29250"
                     /old_locus_tag="HUR99_29255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(1207..1386)
                     /locus_tag="HUR99_RS29255"
                     /old_locus_tag="HUR99_29260"
     CDS             complement(1207..1386)
                     /locus_tag="HUR99_RS29255"
                     /old_locus_tag="HUR99_29260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(1412..1840)
                     /locus_tag="HUR99_RS29260"
                     /old_locus_tag="HUR99_29265"
     CDS             complement(1412..1840)
                     /locus_tag="HUR99_RS29260"
                     /old_locus_tag="HUR99_29265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            complement(2004..2318)
                     /locus_tag="HUR99_RS29265"
                     /old_locus_tag="HUR99_29270"
     CDS             complement(2004..2318)
                     /locus_tag="HUR99_RS29265"
                     /old_locus_tag="HUR99_29270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2306..2584)
                     /locus_tag="HUR99_RS29270"
                     /old_locus_tag="HUR99_29275"
     CDS             complement(2306..2584)
                     /locus_tag="HUR99_RS29270"
                     /old_locus_tag="HUR99_29275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            complement(2759..3124)
                     /locus_tag="HUR99_RS29690"
     CDS             complement(2759..3124)
                     /locus_tag="HUR99_RS29690"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_072354022.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            complement(3121..3492)
                     /gene="tolA"
                     /locus_tag="HUR99_RS29280"
                     /old_locus_tag="HUR99_29285"
     CDS             complement(3121..3492)
                     /gene="tolA"
                     /locus_tag="HUR99_RS29280"
                     /old_locus_tag="HUR99_29285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            complement(3766..4011)
                     /locus_tag="HUR99_RS29285"
                     /old_locus_tag="HUR99_29290"
     CDS             complement(3766..4011)
                     /locus_tag="HUR99_RS29285"
                     /old_locus_tag="HUR99_29290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            complement(4131..7097)
                     /locus_tag="HUR99_RS29290"
                     /old_locus_tag="HUR99_29295"
     CDS             complement(4131..7097)
                     /locus_tag="HUR99_RS29290"
                     /old_locus_tag="HUR99_29295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /protein_id="WP_174892463.1"
                     /translation="MPRRLILSATERDTLLALPESQDDLIRYYTFNDSDLSLIRQRRGD
                     ANRLGFAVQLCLLRYPGYALGTDSELPEPVILWVAKQVQAEPASWAKYGERDVTRREHA
                     QELRTYLQLAPFGLSDFRALVRELTELAQQTDKGLLLAGQALESLRQKRRILPALSVID
                     RACSEAIARANRRVYRALVEPLTDSHRAKLDELLKLKAGSSITWLTWLRQAPLKPNSRH
                     MLEHIERLKTFQLVDLPEGLGRHIHQNRLLKLAREGGQMTPKDLGKFEPQRRYATLAAV
                     VLESTATVIDELVDLHDRILVKLFSGAKHKHQQQFQKQGKAINDKVRLYSRIGQALLEA
                     KESGSDPYAAIEAVIPWDEFTESVSEAELLARPEGFDHLHLVGENFATLRRYTPALLEV
                     LELRAAPAAQGVLAAVQTLREMNADNLRKVPADAPTAFIKPRWKPLVITPEGLDRKFYE
                     ICALSELKNALRSGDIWVKGSRQFRDFDDYLLPAEKFAALKREQALPLAINPNSDQYLE
                     ERLQLLDEQLATVTRLAKDNELPDAILTESGLKITPLDAAVPDRAQALIDQTSQLLPRI
                     KITELLMDVDDWTGFSRHFTHLKDGAEAKDRTLLLSAILGDAINLGLTKMAESSPGLTY
                     AKLSWLQAWHIRDETYSAALAELVNHQYRHAFAAHWGDGTTSSSDGQRFRAGGRGESTG
                     HVNPKYGSEPGRLFYTHISDQYAPFSTRVVNVGVRDSTYVLDGLLYHESDLRIEEHYTD
                     TAGFTDHVFALMHLLGFRFAPRIRDLGETKLYVPQAVQAYPTLRPLIGGTLNIKHVRAH
                     WDDILRLASSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRIERTLFILDWLQSVEL
                     RRRVHAGLNKGEARNSLARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYL
                     ERATQGLVEAGKPVDGELLQFLSPLGWEHINLTGDYVWRQSRRLEDGKFRPLRMPGKP"
                     /name="Tn3-like element TnAs1 family transposase"
     gene            complement(7101..7661)
                     /locus_tag="HUR99_RS29295"
                     /old_locus_tag="HUR99_29300"
     CDS             complement(7101..7661)
                     /locus_tag="HUR99_RS29295"
                     /old_locus_tag="HUR99_29300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220837.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001161490.1"
                     /translation="MQGHRIGYVRVSSFDQNPERQLEQTQVSKVFTDKASGKDTQRPQL
                     EALLSFVREGDTVVVHSMDRLARNLDDLRRLVQKLTQRGVRIEFLKEGLVFTGEDSPMA
                     NLMLSVMGAFAEFERALIRERQREGIALAKQRGAYRGRKKALSDEQAATLRQRATAGEP
                     KAQLAREFNISRETLYQYLRTDD"
                     /name="recombinase family protein"
     gene            8617..10103
                     /gene="ltrA"
                     /locus_tag="HUR99_RS29300"
                     /old_locus_tag="HUR99_29305"
                     /pseudo=""
     CDS             8617..10103
                     /gene="ltrA"
                     /locus_tag="HUR99_RS29300"
                     /old_locus_tag="HUR99_29305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /name="ltrA"
     gene            10208..11893
                     /locus_tag="HUR99_RS29305"
                     /old_locus_tag="HUR99_29310"
     CDS             10208..11893
                     /locus_tag="HUR99_RS29305"
                     /old_locus_tag="HUR99_29310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            11903..12160
                     /locus_tag="HUR99_RS29310"
                     /old_locus_tag="HUR99_29315"
     CDS             11903..12160
                     /locus_tag="HUR99_RS29310"
                     /old_locus_tag="HUR99_29315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            12245..12394
                     /locus_tag="HUR99_RS29315"
                     /old_locus_tag="HUR99_29320"
     CDS             12245..12394
                     /locus_tag="HUR99_RS29315"
                     /old_locus_tag="HUR99_29320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            13879..15843
                     /locus_tag="HUR99_RS29320"
                     /old_locus_tag="HUR99_29325"
     CDS             13879..15843
                     /locus_tag="HUR99_RS29320"
                     /old_locus_tag="HUR99_29325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_071177727.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     BGC             5208..15931
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(12498..13077)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="97.089"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9..640
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.365"
                     /coverage="87.0"
                     /evalue="2.48e-129"
ORIGIN
        1 agagctgtgt tccacggcgg agctggttgc gcgacggctg gggattgcgg cggtacagcc
       61 ggtttaccgc ttcctggaca gtctggtggc gaaagggctg ctggtccggg cgaaataccc
      121 ggttgacggc cgtcaggtca gcgtgtgggg gctgacgccg cacggggtgg cgttctcgtt
      181 cgacgaggac gagccgctga cggacgttat tccgtttcag ccgtcaaggg tgtcggcggc
      241 gcagctgccg caccggctgg ccgtgcagtc cctgcgcctc tccatggagg gccggggggc
      301 caccggctgg cggtacctgc accgtatggc cctgaaaggg atgaaagtgc cggacgcgct
      361 ggcggagctg gacggcagaa cggtggcatt tgaggtagag cgcaccgtca agagccgcag
      421 gcggtatcag gaagtggtgt ccgggtatct gttcaaccgc cgggcgaacg gcatcgatga
      481 aatctggtac atctgccctg accggccgac gcttgtccgg gtacagcggg cgattctggc
      541 ggtggatgaa atcgtgaatc cacagaccgg cgaggcccgc aaaacggtgg agctggaccg
      601 ggagaggctg ttcgcgtgct ttaaatttat gacaacggag tgagggatta tggcgctgta
      661 catggtattt attgaggacg tggaagacaa agacggcgag cgctgcatta tgccaaccag
      721 cgagcatctg gaagacatgg tggtgctcgc ctggcagacc ggggcgtatg ttttctgttt
      781 tgtcgaccgg gcccagcatc tggcgatgat gaaatccatc gggatgtatg acgagcggct
      841 caacagcgac gaaaaagcca cgtacttttt caccggtgaa aatccgcaat gggaacggga
      901 caaacccaca ggaatgaagc tgtgtgatta cctctatcga aaggtggagc ggttcgccat
      961 cgagaacggt gtgcaggtgg ttgatgccgg gaagtgctca ccggagcaga ttaacgcgat
     1021 gattgaggtg gtcagcgagc ggcacgggga aagcgcggtg aacgagaagc tgaaagcgga
     1081 gctgatgcgg gaatataaca gccgctattt taacgtgccg gtgcctgaac tgccggagga
     1141 caaacccgcc cgccggtggt ggccgttcgg caaaaaataa cgccagcacc ggcatggccg
     1201 gtgctgttat tcttccccga gcttatcccg catcacctgc cagagtgttt ccgcatcctc
     1261 gtgaagccgt tcgcacatgt cggccggggt atccatgtcc agctcgttca gcttttccag
     1321 caacagcagc gactgatcct taatgaattt agccatattg agggcagttt tttcctgctt
     1381 cgtcatgttc tccattccct tcggtaagtt ctcagctaaa ccagccggac cagaagcgtt
     1441 ttttcttctg tgtcagttct gttgtcaatc tgtccacttc ggcctggagt ttccggcgct
     1501 catcatcgtg ctggcggcgt tcttcttccc gggatgtttt atcttccagc atcagggtga
     1561 cagcctgccg gagatcggcc agttcctttt gcattgccag aagctgttcc tgtgggaaat
     1621 ttttttgtgt attttcacgg tgtgaaatgc cgggaatttg tttctcaggg atattcacat
     1681 ttccgtatac acggatcagt tctgacacat ccacgacagg gttgtttttc ccgtcacgtg
     1741 acacggtaac ctttccctgt tttacatgat tgtatagcgt tcttctggta atgcccgcgg
     1801 cttgtgctgc ctgtgaaagg ttgagcaatg ttttcgccac tgtatacccc tgattttatc
     1861 gggtgtgaaa ggtgtgtaat ttctcacggt aaatgtatcg ctgaatttta cccgtttttc
     1921 cgttcaggat gtggttttct gacgcgctgc gcttgtcaaa ccggcgacgg ccacgcaatg
     1981 aattgcgccc ccgtcatcgg ttattagagg ctgtctgccc ccggataccc ggattctttc
     2041 tgatgcctga cggtgacgat cacaatctgg tccatttccc ggtcgtggcg gtagagcatc
     2101 acatagccac tgtcgccaaa cccgatcacc agttccttat attccagcgg cagaaacggc
     2161 accgggcggc caatgtctgg caatgttttc agttgctgga tagcccggac gatcacctca
     2221 cctccttttc tggctgccag ccgatttttg gttttgagaa agtcctgaag gcgttgtaaa
     2281 tcgcgctgtg ccagcgcgga aatcgttacc tgtggcatgg cggagcatcc tgctcgttct
     2341 cagttcccca ggtacttatc caggcttccg cttcttccgc agtaaggtgc agacccgttt
     2401 cctgatagtg ctgccatgcg gcctgtccgt cccgcaggta ctggctgcgc ttctcttccc
     2461 ggtcgatgta ttcggtgatt gcctccagca ttagcgcgtg cgctgagcgg tgccggtcat
     2521 cggccagcgt tttcagccgg tccttaagtt cttcatcgag cctgatggat gttgctgatg
     2581 acataaaagc ccctttgtag tcatatgtat tacacatgac tactttaatc cgtggcggcg
     2641 ctatttgcca gaaatacggc ttttgctgcc catttttcag cttcgcttcc actaatcagg
     2701 gctgctacag gctcactcat catccaggac tattgcagcc tgcgggttaa aggacctgtt
     2761 actggcggca accatcatca ttgagctttt gggtggtgac tggtcgcgga tcctgtaagc
     2821 cgtcattttt cagactgaat tcaaaattta taacctgtcg cattgccggg tgccctgcgg
     2881 gatatagcca gtgcctcatt gccgtcagcg tttcccgaaa aaaaaggtga cagccggtaa
     2941 gcgacacgtt gtccactcgt ccatcgtcca gaatatcaaa cgtggcggtc acctgacctt
     3001 cgatgcgttt tgctgcggcc tgtaccgggt aggttggctg cagtgtggtt acgggtttta
     3061 gtggtatcgc atgtaccgga gtgaggaaca tggccgccag cactgtcaga gtaaaagctt
     3121 tcatggtctg aaatccagag gggcgttttt gaatatttgc caggtatttt catccggtgc
     3181 cggcggaatt ttggcgtggg taacggctga tattgctgct ttacagagtt tcggatctcc
     3241 tccttcagca atggcgctgt tcagagtgcc atcacgttgt atggatatcc gcacggtgca
     3301 catttttccc gcataggcct ctggttcaaa catctgcatt tcaacagcgg tcttgatggc
     3361 cgcagcgtag ctactgattt tagatgactt atccagagta taaattttcg gcggctgggt
     3421 ggtggaatgc ttacaggccg tcaggagtaa ggggctgcac aatgccagca ggataaaggg
     3481 tattaaacgc atcgggttga tgacctgtca gtaaaaaatg ttacatgtat atttgtcact
     3541 ctttacggcc acgttcattt acataaacac ggcttatcgt atcgttttta caccaaacgg
     3601 cccgccatgc agttgcgtgc ataggcatgc agcgggttac aatttaccgg gcgcgtttcc
     3661 ggcggttttc cgggtggttt gttgcctgtt ttatcccgta gccgccggaa acgccctcag
     3721 accgtctgag cggtgcgggc aatgcgacgt tatggtaaat accccttacc ggcggcgctg
     3781 tggctgccag gtgaaggtgg tttccgtagc ctcgtatttc tcccgacgca tttcctgcgc
     3841 ccgcctggct tcacgttcgt cctgaatggc acgaagcacc ctttcccgca cctgttgttt
     3901 taccgccttt ggcagcgttt tgttcccttt caggcccatg gccagtgcct gagcgacaaa
     3961 ggcgtccgcc aggcgctttt cttcagcggg agtcagtttc aggtgcgtca tagtggcctc
     4021 cgggcgtctc aggtttcccg aacagtttaa ccgcaggtcc tctcctcatg ccagttagct
     4081 ttcagatgtg tctatacggg gagcccgcag aattcggaaa aaatcgtacg ctaaggtttt
     4141 ccgggcatcc gtaagggccg aaacttcccg tcttccagtc tgcggctctg ccgccagacg
     4201 taatcgccgg ttaggttgat gtgctcccag cccagcggcg acaggaattg cagcagctcg
     4261 ccgtccaccg gcttgccggc ctcgaccaac ccctgggtgg cgcgttccag gtacaccgtg
     4321 ttccacagca cgatagccgc cgtcaccagg ttgaggccgc tggcccggta gcgctgctgc
     4381 tcgaagctcc gatccctgat ttccccaagg cggttgaaga acaccgccct ggccagcgag
     4441 ttgcgcgcct cacctttgtt caggccggca tgcacgcggc ggcgcagttc aacactttgc
     4501 agccagtcca ggatgaacag cgtgcgctcg atccggccca gctcgcgcag ggccacggcc
     4561 agtccgttct ggcgcgggta gctgccgagc ttgcgcagca tcagcgaggc ggtgacggtg
     4621 ccctgcttga tcgagctggc caggcgcagg atgtcgtccc agtgggcacg cacgtgcttg
     4681 atgttcaggg tgccgccgat cagcgggcgc aacgtcgggt aggcttgcac cgcctgcggc
     4741 acgtacagct tggtttcgcc gaggtcgcgg atgcgcggcg cgaagcggaa gcctagcagg
     4801 tgcatcaggg caaagacgtg atcggtgaag ccggccgtgt cggtgtagtg ctcctcgatc
     4861 cgcaggtcgg actcgtggta cagcaggccg tcgagcacat aggtggaatc gcggacgccg
     4921 acattcacca cgcgggtgct gaacggcgcg tactggtcgg agatatgggt atagaacagc
     4981 cgtcccggct cgctaccgta cttcgggttg acgtgcccgg tgctctcgcc ccggccaccc
     5041 gcgcggaagc gctggccatc ggaggatgag gtcgtgccgt cgccccagtg ggcggcaaag
     5101 gcgtggcgat actggtggtt gaccagctcg gccaaggccg ccgaataggt ttcgtcgcgg
     5161 atgtgccagg cttgcagcca ggacagcttg gcgtaggtca ggccggggct cgactcggcc
     5221 atcttggtca gcccgaggtt gatcgcatca ccgaggattg cggacagcag caacgtcctg
     5281 tctttggcct cggccccgtc cttcaagtgg gtgaagtggc ggctgaagcc cgtccagtcg
     5341 tccacgtcca tcagcagttc ggtgatcttg atgcgcggca gtaactggct ggtttggtcg
     5401 atcagcgcct gcgcccgatc cggcaccgcc gcatccagcg gggtgatttt cagccctgac
     5461 tcggtgagga tggcatcggg cagctcgttg tccttggcca ggcgggtgac ggtggccaac
     5521 tgctcgtcca gcagctgcaa acgctcttcc aggtactggt cgctgttcgg gttgatcgcc
     5581 aggggcaggg cctgctcgcg cttgagtgcg gcgaacttct cggccggcag caggtagtcg
     5641 tcgaagtcgc ggaactgccg cgagcccttg acccagatgt cgccggagcg cagggcgttc
     5701 ttcagctcgg acagggcgca gatttcgtag aatttccggt cgaggccttc cggggtgatc
     5761 accagcggct tccagcgcgg cttgatgaag gccgtgggtg catcggccgg caccttgcgc
     5821 aggttgtcgg cgttcatctc acgcagggtc tgcacggctg ccagcacgcc ttgcgcggcc
     5881 ggcgcggcgc gcagttccag cacctccagc aaggccggcg tgtaacggcg cagggtggcg
     5941 aagttctcgc cgaccaggtg caggtggtcg aagccttccg gccgggccag cagctcggcc
     6001 tcgctgacgc tctcggtgaa ctcgtcccag ggaatcaccg cctcgatggc ggcatagggg
     6061 tcgctgccgc tttccttcgc ttccagcagc gcctggccga tcctggagta caggcgcacc
     6121 ttgtcgttga tcgccttgcc ctgcttctgg aactgctgct gatgcttgtg cttcgcgccg
     6181 ctgaacagct tgaccaggat gcggtcatgc agatcgacca gctcatcgat cacggtcgcg
     6241 gtgctctcca gcaccacggc ggccagggtc gcgtagcggc gctgcggctc gaacttaccg
     6301 aggtctttgg gcgtcatctg cccaccctcg cgggccagct tgagcaggcg gttctggtgg
     6361 atgtgccggc ccaggccttc gggcaagtcc accaactgaa atgtcttcag ccgctcgatg
     6421 tgttccagca tgtgccgaga gttgggtttc agcggtgcct ggcgcagcca ggtcaaccag
     6481 gtgatgctgc tgccggcctt gagcttcaac agctcgtcca gcttggcccg atgcgagtcc
     6541 gtgagtggtt cgaccagggc gcggtagacc cgccgattgg ctcgcgcaat ggcttccgag
     6601 caggcccggt caatcacgct cagcgccggc aggatgcgtc gtttctgccg taggctctcc
     6661 agggcctgac cggccagcag caagcctttg tcggtctgct gggccagctc ggttagctcg
     6721 cgcaccaggg cgcggaagtc ggacaggccg aacggggcca gttgcaggta ggtgcgcagt
     6781 tcctgggcat gctcgcgacg ggtcacgtcg cgctcgccgt actttgccca gctcgccggc
     6841 tcggcctgga cttgcttcgc cacccacagg atgaccggct cgggcagctc gctgtcggtt
     6901 cccagcgcgt aaccggggta gcgcagcagg cagagctgca cggcgaagcc gaggcggttg
     6961 gcgtcgccgc gtcgctggcg gatcagcgac aggtcggagt cgttgaaggt gtagtagcgg
     7021 atcaggtcat cctggctttc cggcagcgca agcagggtgt cccgctccgt ggccgagagg
     7081 atcaagcgac gcggcatgtg tcagtcgtcc gtgcggaggt actggtagag ggtttcccgg
     7141 ctgatgttga actcgcgggc aagctgcgcc ttgggctcgc cggccgtcgc tcgctgccgc
     7201 agggtagcag cctgctcatc ggacagggct ttcttgcggc cccggtacgc gccacgctgc
     7261 ttggccaagg cgatgccctc acgctgccgc tcgcggatca gggcgcgctc gaactcagcg
     7321 aaggccccca tcaccgacag catcaggttg gccatcggcg agtcctcgcc agtgaacacc
     7381 aggccctcct tcaggaactc gatgcgcacg ccgcgctgag tcagcttctg taccaagcga
     7441 cgcaggtcat cgaggttgcg ggccagccga tccatgctgt gcaccaccac tgtatcgcct
     7501 tcgcggacga agctcagcag cgcttcgagc tgggggcgct gggtgtcctt gcccgatgcc
     7561 ttgtcggtga acaccttgct cacctgggtt tgttccagct ggcgttccgg gttctggtca
     7621 aagctgctga cccggacgta gccgatgcgg tgcccctgca cgatgtctcc ttggttgaag
     7681 gcggcttaag tgcactttct gttccgttgt gcctcaaagc ccatttctgt caggctgaaa
     7741 tctataacct tcgcgggcat gtgtcaaaaa atgggaaagc agactctatt ctgacgaagc
     7801 ggcgcggccc tgcctgacat caagttaggg tatagcctag attgacatgc gcgatgcaac
     7861 ccttaacttg cttgcaccta tcgtttccat gctagcttta tcgtaacgct aaggaagctc
     7921 tgaaaaagcc catgtttcgc gaaatcaccg ctctgtaacc cgcatggttg ctgggatgca
     7981 tttctcgagc gggggctttt tcagaccttc cttagcttag cgtacgattt tttccgaatt
     8041 ctgcggttcc ccctatacca tctgaaatgt aagtgtgatg aatgtcttaa ataataaaat
     8101 ttgttgccat gagaaatttt cgggaaaaga cgcgatctgc ttacaggtgg ctccgggcgc
     8161 ttttttgtgc ctgaagatga gaactaatct catatattga cacctgaaaa cgggaggagt
     8221 aaggtaataa ttatactgtg tatatgtaca gtgtgcgccg ggagaccggt tagagatcaa
     8281 ggggtgaaag tccccgacca ttgaaggacc agcaatccac aaggtccccg agtcatgcgt
     8341 tgcataccgc gaggtatggg gcgaagcgtt gacaggggtg ttgacaggcc agccattgag
     8401 ccacgaaatg tatattaaat taccgggtgc cgacgttgta ctgttaacgg aaggcaacat
     8461 catagggtgc gacactgcga gtgccacatg gacccggcgg ggtctgagac cctggcatgt
     8521 caatacgatc tctacgcggg aaccgggaga tctcccctct gaccatctgc cagtgtcgga
     8581 gatggcccgc accgggaaga cgaggagtca tagccggtga tgtacggaga ggagaagtcg
     8641 gactcgctca tagtagcggc gaagcaggcg aacaacccga aaggagcgga gtcagtggag
     8701 cgaaggagcg gggccaaggg aacgcggaac agccacacat gcgccggaca cagagccggg
     8761 aaagcatgtc acagaggctg tcacgcgtgc gggaagctgc gaagcagcgg aagaaagaac
     8821 ggtttacagc attgttccac ctgctgacag tcgaagcact ggaagccgca ttcctctccc
     8881 tgagcaggaa agcggccgcc ggagtggatg gcatcaggtg gatggactac gccggaaaca
     8941 tgaagaacaa cataacagat ctgcaccgga ggctacatca gggcagctac agggcgcagc
     9001 ccggcaggcg tcactacatc ccaaaagcgg atggaaaaca acgcccgctc ggcatcgcct
     9061 cgctggagga caagatcgtc cagtatgcgc tggtgaaaat cctgaacgca gtctatgaaa
     9121 acgactttat ggggttctca tacgggttca gacccgggcg aagccagcac gatgcactgg
     9181 acgcactggc cacagggctg gtacgcacta acgtaaactg ggtactggat gccgacatca
     9241 gtcagttctt cgacagggtg agccacgaat ggctgatcag gttcacagag catcggatcg
     9301 gcgaccggag ggtaatcagg ctcatacgta agtggctcac agccgggacg tcggaggagg
     9361 gtcaatggcg agcaacggag gaaggcaccc cacagggtgc ggtcatctca ccgctgctgg
     9421 caaacatata cctccactac gtcttcgatc tgtgggcgca tcagtggcga cgtcgctatg
     9481 ccacaggcaa tgtggtaatg gtcagatacg ccgatgacat cgtcatcggg ttcgacaaac
     9541 gatacgatgc ccggcgcttc cgtatagcca tgcagcgcag actgagggag ttcggactca
     9601 cggttcaccc ggagaaaacc cgtctgatgg agttcggccg cttcgctgcc gaaaaccgtg
     9661 ccatcagggg aaaaggcaaa ccagaaacgt tcaacttcct cgggttcacg cacatcagcg
     9721 ggaaagatcg caacggcagg ttcatgctga tacgaaagac ccgccgggat cggatgacgg
     9781 caactctgaa agccatcaaa gacggtctgc gaaggcgctg gcattactca atccccgaac
     9841 agggaaaatg gctcaggaga gtggttcagg gatacctgaa ctatcactcg gtaccgggca
     9901 acttccccac catgcagaag ttcaggacac acgtaacaaa cctctggcgc cgggcgctca
     9961 ggcgcaggag ccagaaggat gatacgacct ggacgaaagc aaacaaactg gcagccgcat
    10021 ggctaccaag ggttcgggtt cttcatccat ggcctgtgga gcggttcacc gccagacacc
    10081 cgaggcagga gcccggtgcg taaatcgcgc acgccgggat ctgtgcgggg ggtatccggt
    10141 aacgggtatc cctaccgcga catgttggct ttaatttatt gttttaaatg tcaaagagga
    10201 aaacggtatg agtggtggag acggtcgagg tccgggtaat tcaggtctgg gacataatgg
    10261 tggtcaggcc agtgggaatg tgaacggtac gtctggtaaa ggtggccctt catcaggtgg
    10321 tggtacggat ccaaacagcg ggccgggctg gggtacgacg catacgccga atggagatat
    10381 tcataactat aatccggggg agtttggtaa cggcgggagt aaacccggtg gtaatggtgg
    10441 taacagcggc aatcatagcg gtagctctgg tggcggacag tcttcggcca ctgcgatggc
    10501 cttcggtctg cctgccctgg ctactccggg ggctgaagga ctggctttat cagtttccgg
    10561 cgatgcgttg tcggccgccg ttgctgatgt gctggctgcc ctgaaggggc cgtttaagtt
    10621 tggtctgtgg gggattgcga tctacggtgt gctgccttct gagattgcaa aagatgatcc
    10681 gaaaatgatg tcaaaaatta tgacgtcatt accggccgat gcggtgacgg agactccggc
    10741 aagtacttta ccactggacc aggcgacggt tcgtgtcaga caacgggttg tggatgtggt
    10801 gaaggatgag cggcagcata ttgcggttgt cgcaggtcgg ccaatgagtg tccctgtggt
    10861 ggatgcgaaa ccgacaaaac gtccgggggt attcagtgtg tcgattccgg gtctcccgtc
    10921 tctgcaggtg agcgtaccga aaggtgttcc gacagcgaaa gccccgccaa aaggcattgt
    10981 tgctgaaaaa ggtgattcac gtccggctgg ttttacagcc ggtggtaact cccgtgaggc
    11041 cgttattcgt ttcccgaaag agaccggaca gaagccggtt tatgtgtcgg tgacagatgt
    11101 tcttaccccg gcacaggtaa aacagcgtca ggaggaagaa aagcgtcgcc agcaggcatg
    11161 ggacgccgct catccggaag aggggctgaa aagagactat gataaagcga aagctgagct
    11221 ggatgccgaa gataaaaata ttgcgacctt aaacagccgc attgcatcga cagagaaggc
    11281 gctccccggt gcaagggctg ctgttcagga agccgataaa aaggtaaaag aggcagaggc
    11341 aaataaagat gattttgtga cttataaccc gcctcatgaa tatggctccg ggtggcagga
    11401 tcaggttcgc tatcttgata aggatattca gaatcagaat gagaaattaa aagcggctca
    11461 ggcatcttta aacgcaatga atgaatcctt atccagagat aaggctgcac ttaccggggc
    11521 gatggagagc cggaaacaaa aggagaaaaa agcgaaggat gcagaaaata agttaaatga
    11581 ggaaaagaac aagcctcgca aggggactaa agactacggc catgattatc atccagtacc
    11641 taaaacagaa gacataaagg gacttggaga gttaaagcga ggtgatccta aaacacctaa
    11701 acaaggtggt ggtggtaagc gggcccgatg gtatggcgat aaaaaacgta aaatttatga
    11761 atgggattcc cagcacggtg agcttgaagg gtatcgtgcc agtgatggcg aacacctagg
    11821 cgcatttgat cccaaaacgg gtaagcaggt taaagggcca gatccaaaac ggaacattaa
    11881 aaaatatctt tgagaggtaa atatggggct taaattacgt ttgacatggt ttgataagaa
    11941 aactgaagag tttaaagggg aagagtattc taaagacttt ggtgacgatg gttctgtcat
    12001 tgaaagcttg ggaatgcctt taaaggataa tattaataat ggtgagtttg atttgaagaa
    12061 agaatgggtt cctttactac agccattttt taaaaatcaa ataaaacctg atgtggataa
    12121 ttgttatata gcttttgatt atcgggacgg taactggtaa caaaaaatta tcaaggatga
    12181 tttgaaatac tgacttccgg tgttcaggga tgaatgccgg agtctttaaa tacagggaaa
    12241 gtatatgaaa aaggtaaaga ctatttttct ttttatattg attgttgctg gctttcttct
    12301 ggccgcatgt caggcaaatt atatccggga tgttcagggc ggaacggtgg caccatcgtc
    12361 ctcctctgaa ctgacgggga tcgcggttca gtagaaaaga tcaaaggatc ttcttgagat
    12421 cctttttttc tgcgcgtaat cttttgccct gtaaacgaaa aaaccacctg gggaggtggt
    12481 ttgatcgaag gttaagtcag ttggggaact gcttaaccgg gtaactggct ttcgagagca
    12541 cagcaaccaa atctgtcctt ccagtgtagc cggactttgg cgcacacttc aagagcaacc
    12601 gcgtgtttag ctaaacaaat cctctgcgaa ctcccagtta ccaatggctg ctgccagtgg
    12661 cgtttttgcg tgtctttccg ggttggactc aagatgacag ttaccggata aggcgcagca
    12721 gtcgggctga acggggggtt cgtgcttaca gcccagcttg gagcgaacga cctacaccga
    12781 gccgagatac cagctgtgtg agctatgaga aagcgccaca cttcccgcaa gggagaacgg
    12841 cggaacaggt atccggtaaa cggcagggtc ggaacaggag agcgcaagag ggagcgacct
    12901 accggaaacg gtggggatct ttaagtcctg tcgggtttcg cccgtactgt cagattcatg
    12961 gttgagcctc acggctccca cagatgcacc gaaaaagcgt ctgtttatgt gaactctggc
    13021 aggagggcgg agcctatgga aaaacgccac cggcgcggcc ctgccgtttt gcctcacatg
    13081 ttagtcccct gcttatccac ggaatctgtg ggtaactttg tatgtgtccg cagcgcccgc
    13141 cgcagtctca cgcccggagc gtagcgaccg agtgagcgag gaggcgcaat ttccccggca
    13201 cctgcaagac ggtcaccgga cgcgctgatg tgggatattg tcccctgatt aagtctttct
    13261 attccctgac gatcaattat caggataggt gaaccatgtc ggtttttcgc tgaacatttt
    13321 acgttaacct atctctgttg cttttttctc cttgcggaga aatgcaagtc atccccgctg
    13381 gggcgtggct gacttcaggg gaaaagacct tgcttacgct ggctggacgc caccgacgca
    13441 cggtcttttc ccctctttct ggctctgtcc ggctggacgc cggccacgcc agaaattcac
    13501 ccggcccccg tcaggctcac gcctgaccac ccacaaaaat ccacggtgct ggacgcacct
    13561 gacgaagcag caaagctgct cctgattttg cgggtggtca gccgctcgct atggcgaact
    13621 ctgacggggg ccggaacacc ggaaaagacc gcactggggt gccgcctttt cctctcacac
    13681 gctggggcgt gctcgttgtt cctccggggc tgcgcctttt ccgcatgggg cggaaagagg
    13741 ctggcctccg cggtgaaagc tgaacgcaat caccacggac gtgaccgccg ccgccatgcc
    13801 ttggggcatg tccgcggctt gtgcagcggg ggctgcgcat cacgccggta aacccgtcgt
    13861 ctgaaggaga gagattgcat gtttaatacg gattcgcttg cctggcagtg gcatatcccg
    13921 gagctggccc ggcagattta cccgtgggtc agctggctgt accgggagta ttacagtctg
    13981 gccggttttt ttctggttat cggcctgttt ttcggtctgg ctgaactctg ggccggccga
    14041 atgcgttttg tggggctgag ccataaggcg cggcgggagt atgccgatcg ctataagcgc
    14101 gataataacc ggactgtgcc attttcggtg ctggcctcgc tggattcacc cgggcggatg
    14161 gtcagggcac ggcgacatgt ctggaactac gcgtactggc tgaccggcgc tgccggtctg
    14221 gcccttctgg gggggctggt tgtcgccgtg tttatcgaga gctggggaga aaccgtcctg
    14281 cgcccggacc tctatgcgaa cgcagattat tacctgctgc agccggctaa cctgttcggg
    14341 atagcctggt gtgccggagg gcttgtcgcc ggcgtccttc tggcgcggct gctggcgttc
    14401 ctgctgcttg atggtcattt tgcggccgct gacgaggcgg tgaacgcgaa actgaatcag
    14461 gagagccggc gcagcagcca gcggaccgga gaaatgacag acgtccgcca cctgcatttc
    14521 ggggagccgg taccggttaa cgcgctggcc gatttttcca cggagcaggc ccggaaacag
    14581 caggcggtgt ttctgggtaa ggatgagcag ggccagccgg tgctggtccc tcgtgatacc
    14641 tggcgcaaga ccaatattca gatcctcggc ctgcccggga gcggcaagag cgcgatggcc
    14701 accaacgcgc tcattcgctg cgtacgcgat ttcggggacg ctgtggtgta cttcgacccc
    14761 aaaggggacg cgtgggcgcc gcacgtcttc cgggcgcact gcccggactt caccctgctg
    14821 gatctgcggc cggggaaacc ggcgcagctg aatctgttcc gcgatctcga ccagtacgcc
    14881 ctgaagaatc tgctggttgc cgggtttaac ctgagtgaga ccggcgacgt ggcggaccac
    14941 taccgcatca gcgagcagaa agcggcgaag ctgattgcgg agcagttccc gcagggggca
    15001 aacattcagc aggtgctggc ggcggcgtac gcgttgccgg aggccctgaa aaaggacgtg
    15061 aaggggctga tcaccaagct ggagaacgtg gccgacctga gcgtcctgca gacggacagc
    15121 ggtatcgatg tggcggggat aatcaacggc ggcggctgcc tgtacgtcat cggctcgatg
    15181 gacgatgagg cggtgatccg ggtgcagaag atgctgtttg cccgctgcgc gcaaatcatc
    15241 attgcgcggg atgagttccg gaggtggccg cacgcgagca tcatgctcga tgagattaaa
    15301 tatctgctgt cgaagtacgt gctgaacgcg ctggggacgc tgcgcagccg ggactgcaac
    15361 ctgctgctcg cgcaccagtc gctgggcgac ttcggtcagt gcgggcagga tctgcccgct
    15421 gattttgtga aaaccacggt actggataac acgccgatcc gctggttcta tcgcgcggcc
    15481 agccaggagt ccgcgcagtg ggcggcgggc cagaccgggg agatccgggt ggacgtggag
    15541 cgccgccggg ccagccggga ggcggggaac gtggagcaca tcagcggcga cagcttcatc
    15601 cagaaggagg cgcggccgct gtttgacgtg aacaccctgc aacacctgcc tgacgggttc
    15661 gcggtgatga ccgggctggg cgtggcgcgg ctggcgttca gcagcccgct gcgggttgag
    15721 cgccgggaaa tttcgctgaa aaccttcccg gtgctggcga aaacggaccc gctggcggag
    15781 tacctgcctc cggccgacgg cggcggacca aaagcggatg atgattttgc ggggctttac
    15841 tgatgacact ggagcagtac aacgtcagcc acgcgaagcg gcaggcgcgg aacgcggaga
    15901 aaacacggct gaccctgcgc tggctgcggg a
//
