LOCUS       NZ_CP054743             5596 bp    DNA     circular CON 16-MAY-2024
DEFINITION  Klebsiella pneumoniae strain KP20194c5 plasmid pKP20194c5-p5,
            complete sequence.
ACCESSION   NZ_CP054743
VERSION     NZ_CP054743.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15186444
            Assembly: GCF_013348985.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5596)
  AUTHORS   Hu,L.M., Zhang,X.T., Zeng,X., Chen,Y., Liu,L. and Li,G.Q.
  TITLE     Genomic Characterization of a Carbapenemase-Producing, Extensively
            Drug-Resistant Klebsiella michiganensis Strain from a Renal Abscess
            Patient
  JOURNAL   Microbiol Resour Announc 11 (12), e0082522 (2022)
   PUBMED   36321904
REFERENCE   2  (bases 1 to 5596)
  AUTHORS   Zhang,X., Ouyang,J., He,W., Zeng,T., Liu,B., Jiang,H., Zhang,Y.,
            Zhou,L., Zhou,H., Liu,Z. and Liu,L.
  TITLE     Co-occurrence of Rapid Gene Gain and Loss in an Interhospital
            Outbreak of Carbapenem-Resistant Hypervirulent ST11-K64 Klebsiella
            pneumoniae
  JOURNAL   Front Microbiol 11, 579618 (2020)
   PUBMED   33281772
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5596)
  AUTHORS   Zhang,X.T. and Liu,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2020) Clinical Research institute, The Second
            Affiliated Hospital, University of South China, 35 Libration Ave.,
            Hengyang 421001, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 23-JAN-2020
            Assembly Method                   :: SPAdes v. 3.14
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013348985.1-RS_2024_05_16
            Annotation Date                   :: 05/16/2024 02:49:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,905
            CDSs (total)                      :: 5,783
            Genes (coding)                    :: 5,614
            CDSs (with protein)               :: 5,614
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 169
            CDSs (without protein)            :: 169
            Pseudo Genes (ambiguous residues) :: 0 of 169
            Pseudo Genes (frameshifted)       :: 64 of 169
            Pseudo Genes (incomplete)         :: 113 of 169
            Pseudo Genes (internal stop)      :: 23 of 169
            Pseudo Genes (multiple problems)  :: 31 of 169
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054743.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5596
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP20194c5"
                     /serotype="ST11-K64"
                     /isolation_source="monitor panel"
                     /db_xref="taxon:573"
                     /plasmid="pKP20194c5-p5"
                     /geo_loc_name="China: Hunan"
                     /lat_lon="27.72 N 112 E"
                     /collection_date="2019-04-15"
                     /collected_by="Xiaotuan Zhang"
     gene            complement(356..514)
                     /locus_tag="HUS05_RS29850"
     CDS             complement(356..514)
                     /locus_tag="HUS05_RS29850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     gene            1154..1330
                     /locus_tag="HUS05_RS29265"
                     /old_locus_tag="HUS05_29270"
     CDS             1154..1330
                     /locus_tag="HUS05_RS29265"
                     /old_locus_tag="HUS05_29270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     gene            1320..1664
                     /locus_tag="HUS05_RS29270"
                     /old_locus_tag="HUS05_29275"
     CDS             1320..1664
                     /locus_tag="HUS05_RS29270"
                     /old_locus_tag="HUS05_29275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062955149.1"
                     /translation="MAVKRTRFLGIRVTDGEYQQLLERCNGRQLAVWMRETCLDTRPAR
                     SLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRVQVVAALMAIDAELERLRHA
                     VLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            1873..>2307
                     /locus_tag="HUS05_RS29715"
                     /pseudo=""
     CDS             1873..>2307
                     /locus_tag="HUS05_RS29715"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            2342..2851
                     /locus_tag="HUS05_RS29280"
                     /old_locus_tag="HUS05_29285"
     CDS             2342..2851
                     /locus_tag="HUS05_RS29280"
                     /old_locus_tag="HUS05_29285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            2858..3070
                     /locus_tag="HUS05_RS29285"
                     /old_locus_tag="HUS05_29290"
     CDS             2858..3070
                     /locus_tag="HUS05_RS29285"
                     /old_locus_tag="HUS05_29290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            3737..3961
                     /locus_tag="HUS05_RS29290"
                     /old_locus_tag="HUS05_29295"
     CDS             3737..3961
                     /locus_tag="HUS05_RS29290"
                     /old_locus_tag="HUS05_29295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            3945..4211
                     /locus_tag="HUS05_RS29295"
                     /old_locus_tag="HUS05_29300"
     CDS             3945..4211
                     /locus_tag="HUS05_RS29295"
                     /old_locus_tag="HUS05_29300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(4281..4631)
                     /locus_tag="HUS05_RS29300"
                     /old_locus_tag="HUS05_29305"
     CDS             complement(4281..4631)
                     /locus_tag="HUS05_RS29300"
                     /old_locus_tag="HUS05_29305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197756.1"
                     /translation="MYWLIAFLAFIFPGRSFADGYTAYYRCNGTQEASLTVKDNKLSMV
                     VGLSKFNRQLDTYRFKEKGIEVVMQRAASDDNSEAIMSFIMPDVNNMTLLVKNNGYIIV
                     KTTCWLTKTDKQ"
                     /name="hypothetical protein"
     gene            complement(4697..5242)
                     /locus_tag="HUS05_RS29305"
                     /old_locus_tag="HUS05_29310"
     CDS             complement(4697..5242)
                     /locus_tag="HUS05_RS29305"
                     /old_locus_tag="HUS05_29310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            complement(5268..5594)
                     /locus_tag="HUS05_RS29260"
                     /old_locus_tag="HUS05_29265"
     CDS             complement(5268..5594)
                     /locus_tag="HUS05_RS29260"
                     /old_locus_tag="HUS05_29265"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     Typing          989..1068
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="90.361"
                     /coverage="97.0"
                     /evalue="1.1100000000000001e-21"
     Typing          complement(406..803)
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          1655..3186
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.804"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cccccccttg ctattgcgtt ttttgttgcg cacaaagcta ccattgcgca ttaagaaacg
       61 caataaaaaa ggagggaggg agtggtttgt acatgatgtg cagtgcgctg agggcatcag
      121 tggcgggtgt ttttccgtgg gatggatgga gctccgggga taacagaact gacgatcatt
      181 taaaggatct tcttgagatc ctttttttct gcgcgtaatc tcttgcactg taaacgaaaa
      241 aaccgcctag ggaggcggtt tgatcgaagg ttaagtcagt tggggaactg cttaaccggg
      301 taactgggta tacgagaccg cagataccaa aactgttctt tcagtgtagc cgcagttagg
      361 cacccacttc aagacctctc aatatctctc tcgtatatat ccagttacca atggctgctg
      421 ccagtggcgt ttttgcgtgt ccgtccgggt tggactcaag atgatagtta ccggaaaggg
      481 cgcagcagtc gggctgaacg gggggttcgt gcatacagcc cagcttggag cgaacgacct
      541 aaaccgagcc gagataccag cagcgtgagc tatgagaaag cgccacgctt cccgaaaggg
      601 aaaaaggcgg aacaggtatc cggtaaacgg cagggtcgga acaggagagc gcacgaggga
      661 gccgccggag agaaatcacc ggcatcttta agtcctgtcg ggtttcgtcc tcctctgact
      721 tgagcgtcca tttctgtgat gctcgtcagg ggaggcggag cctatggaaa aacggcaacg
      781 ccgcatcctt ttctccggcc ctttctgatt tgagcgcctt tgctttatcc cgttatccgt
      841 gagtcggtca cgcccgccgc agccgaacgg caggagcgca gctaccgagt gagcgaggag
      901 gcgtcatttc atctgtccgt gcatggtatt gcggacgctc ctgagccaca tatcacacct
      961 gccacatgag gcactttcat gaatcgtgct ctcatgccaa catagtaagc cagtatacac
     1021 agcgtaaacg ctgtgactgg ttcagggctg cgccccgaaa cccgctaaca ccactgacgc
     1081 gctggcgctt gtccaacgcc ggagcgaccc ggaaaacttt tccgtgccgt ccggcgtttg
     1141 cgaaggaggg ataatgcaga agccgaagaa gaagccgctc gtcgtaaaaa aaagatcctg
     1201 gcatccggca gtgatggcaa atctgatgcg tcaggcacag gaggaagatt accgccggga
     1261 gcagatggca gagcttgagc gttcagcccg gtcacatttt gcggatatcg gaggagagga
     1321 tggcggttaa gcgtacccgt tttttaggta tccgggtgac cgatggggag taccagcagc
     1381 tgctggagcg ctgcaatgga aggcaactgg cggtgtggat gcgggaaacc tgtctcgata
     1441 cgcgcccggc gcggtcgttg cggctgccgt ccatcgatcc ggttttgctg cgccagcttg
     1501 ccgggatggg gaacaacctc aaccagatcg cccggaaaat taacggcggc cagtggtcag
     1561 gcgctgaccg ggttcaggtg gtggccgcgc tgatggccat tgatgccgaa ctcgagcggc
     1621 tgcggcatgc cgtgctggaa aagggggcag acgatgatcg ttaagtttca tccgcgaggg
     1681 cgaggcggcg gtgccgggcc ggtggattat ctgctgggga aagaccgcca gcgcgacggg
     1741 gccatcgtcc tgcagggaaa gccggaggag gtccgggagc ttatcgacgc ctcgccctac
     1801 gccaaaaagt acacctccgg cgtcctgtct tttgctgaac aggatttacc gcccggccag
     1861 cgtgaaaagc tgatggcgag cttcgagcgg gttctgatgc ccggactcga taaagaccag
     1921 tacagcgtgc tgtgggttga acaccgggac aaggggcggc tggaactgaa ttttctggta
     1981 ccgaacacgg aactgctgac cggcaggcgt ctccagccgt actacgaccg ggcagaccgt
     2041 ccgcgcatcg atgcgtggca gaccgtggtg aacgggcgac tggggctgca cgacccgaac
     2101 gcaccggaga accggcgcgc gctggtgacg ccatcttcgt tacccaaaac gaagcaggaa
     2161 gccgcagagg ctattacgcg gggcttactg gccctcgcct cgtcagggga gcttaaaacg
     2221 cgtcaggacg tcactgaggc gctggaaagc gcaggttttg aggtcgtgcg caccacaaag
     2281 agcagcatca gcattgccga cccggacgga gggcgaaaca tccgacttaa gggagccatc
     2341 tatgaacagt cttttaacgc tggcgaagga cttagagcag aaatcgaaag cgcagcagca
     2401 gagtaccggc gaaatgctga aagccgcatt cagcgagcac gagaagtctg tcagagcgga
     2461 actgagcgaa agcgggaaga gaatcagcgc cgccatccgc gcccacgagc agggtatgag
     2521 cgcggccatg cagtcgaacc gcctgagcgt gatgcgtatg gtcgggcgga catggctgac
     2581 catcacgatg gtgtcaggac tgctgttcgc cagcctgagc ggggtgttgt ggtatcaggg
     2641 gagcttgata gcgtcaaatc tggccgaaat cgaccggcag aacgcagcgc tgtcgaagct
     2701 gaacgcgaag acctggggcg tgacgtacct ggaagacagc aacggacgtt ttctggtgct
     2761 gccgaagggg acggccgtag acaggacgca gagctggacg gtcgggaacg ggcggtcgaa
     2821 gcagaacgcg ctgagactgg tgaaggagta agtgccgatg accgagctgg aaaaacagtt
     2881 gctgagcgca ttagagcagc tacagcagga ctactcgaaa aggctggacg agtgggagag
     2941 cgccttcggg gaatggcgga aaatgtcagg gcttatgcaa cgggagaacg cggcgctgag
     3001 cgagcgcgtg acgcgcttga gtcagcaggt ggaacgcttg agcgggcaac tgcagcgttt
     3061 gagccggtag tgcagcgtca tgagatggcc gtggccgcag aacgggcgca cgagcaacgg
     3121 cagcacgaaa aggaactgac ggaagcgcgt tcccggcagc gaagctatga cggtccgtcg
     3181 ctgggctgaa atgcaggaaa acagggttct catcgggcat ttacgctgaa accggatgtc
     3241 attcacctgg ctgcatggct atgcagccag gtaaaattta tctgtcgcga acggggcggt
     3301 ttatcgggtg gtttgttgcc ggttttacct gactgccacc ccgttcgcgg cgaacccgtc
     3361 cggggcggtg cgggcaacgg gtgttatgtt taatcagcgt gaacggcaga tacaaaaaag
     3421 ccccggaggg cttttaacta ctgacttatt tttttgaaga tttgctgggt ttcaatttgt
     3481 cagtatttcc cggcgttttt ttattgtcac gctggcgttt atcaggttcc cctgttgaat
     3541 cggcaattcg tttcggaccc ggcttaagac ccataatcgt tatcctttca atagttaaga
     3601 ggaaagccct caagctagat atattgaccg cgttacggat tatcaagagg ggctaacaag
     3661 attatttttt gttcttttag gttgattgtg gtactgttga tatacatgta tagcaaatgg
     3721 tgttcgggag gtttatatgc ttgctatccg gttatctgat gagattgagt cccgtctgga
     3781 ctcgctggcg aagcaaaccg gcagaacaaa gacgttttat gcgcgggaag caatactggc
     3841 gcatctggaa gacctggagg attattatct ttcagcagaa actgctgcac gcgttcgccg
     3901 tggtgatgaa gcagtgcatt cgtctgaaga cgtgaggaag tcacttggtc tggacgatta
     3961 actattccga tcgggcgctc aaatcgttac gcaagatgga caaacagaac gcacgacgga
     4021 ttgtggattt tatgagttta cgcattgcag ttgctgccga tcctcgccag tcagggaagc
     4081 cgctcaaagg tgagctgggc gagttctggc gctatcgggt gggagattat cgcgttctgt
     4141 gtgagatccg agatgacgag cttgttatcc ttgccgccac gattggacat cgccgcgaag
     4201 tttacgactg aagcccgcta tgcgggcttt tttgatgccg acaacaggta ttatggtaaa
     4261 tactcgacta actacgtgtt ctactgtttg tcggttttag ttaaccagca ggttgtctta
     4321 acgataatgt agccgttatt tttaactaat aaggtcatat tgttaacgtc aggcataata
     4381 aaagacatta tggcctcaga gttatcatca gaagcagctc tctgcattac tacttcgatt
     4441 cccttttctt tgaatctata agtatccagt tgcctattaa acttagaaag acctacaacc
     4501 atacttagtt tgttatcttt aacagtaaga gatgcttcct gagtaccatt acatcggtag
     4561 taagcggtgt aaccgtcagc aaaagatcga ccggggaata taaatgctag gaacgcaatt
     4621 aaccaataca tagttgagaa tcttggtatt acacatttca ctatcctctc tttcattttt
     4681 cgttcaccat actttgttat ctgattttta atttttctat tttataaacc aagtctctac
     4741 caaaaaggcg aaaattatcc tcaaataata ataattgttt aagaacatcc atgaaagcag
     4801 ctgcttcacc ctcagttatg ggagctactc tatataacat ataacctgag ttaagggttt
     4861 cttttatact ttcttcaatg ctcattataa atattagtgg attatcattt ttcttccccc
     4921 atgggtttct aattaatcct tcgatgtact caggtccttt gcgtcctatt gcctgcgcaa
     4981 tattttttat ttcatctgcg tgagggcttt gttgtacagc tttgtttatg cctgcttgag
     5041 tgattttcag agactctaca ccgtgtatgt tgtatgagat aaaatgtaat aaattaagat
     5101 gcaatgcaat taatccattt ttgtttacat ctgagtattt ggataaaaaa cgtaatgaag
     5161 tgttaactct cccttgaagc ctaacaattg ggagtgctgc cttgtatatt tccttctccg
     5221 ttaaataccg tttaaaaaac ataattctcc gcctccgtat agcgtgccta ttttatttcg
     5281 tcgtaaaact tagctctgaa atattccttt agaaccatca tgtcattaat aattgaatct
     5341 atctcatcca ttttttcttg gtattctttt aatggtgaag ggagcggtaa ctcaatattt
     5401 gaaaagtgat tggcgagata gggatcaagg tttctcatcc attcaggctt ttcgccaatg
     5461 cgttcttcaa ctgaaagtga acctgataat ctctggttaa taagatcact tagactcatt
     5521 ttggttttat tcgaaagccg ttgtaaggat tgctttaatc ctatatctag catgatattt
     5581 gttctttctc tcatta
//
