LOCUS       NZ_CP054725             5596 bp    DNA     circular CON 16-MAY-2024
DEFINITION  Klebsiella pneumoniae strain KP20194f plasmid pKP20194f-p5, complete
            sequence.
ACCESSION   NZ_CP054725
VERSION     NZ_CP054725.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15186447
            Assembly: GCF_013348905.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5596)
  AUTHORS   Hu,L.M., Zhang,X.T., Zeng,X., Chen,Y., Liu,L. and Li,G.Q.
  TITLE     Genomic Characterization of a Carbapenemase-Producing, Extensively
            Drug-Resistant Klebsiella michiganensis Strain from a Renal Abscess
            Patient
  JOURNAL   Microbiol Resour Announc 11 (12), e0082522 (2022)
   PUBMED   36321904
REFERENCE   2  (bases 1 to 5596)
  AUTHORS   Zhang,X., Ouyang,J., He,W., Zeng,T., Liu,B., Jiang,H., Zhang,Y.,
            Zhou,L., Zhou,H., Liu,Z. and Liu,L.
  TITLE     Co-occurrence of Rapid Gene Gain and Loss in an Interhospital
            Outbreak of Carbapenem-Resistant Hypervirulent ST11-K64 Klebsiella
            pneumoniae
  JOURNAL   Front Microbiol 11, 579618 (2020)
   PUBMED   33281772
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5596)
  AUTHORS   Zhang,X.T. and Liu,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2020) Clinical Research institute, The Second
            Affiliated Hospital, University of South China, 35 Libration Ave.,
            Hengyang 421001, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 23-JAN-2020
            Assembly Method                   :: SPAdes v. 3.14
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013348905.1-RS_2024_05_16
            Annotation Date                   :: 05/16/2024 02:47:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,918
            CDSs (total)                      :: 5,796
            Genes (coding)                    :: 5,618
            CDSs (with protein)               :: 5,618
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 178
            CDSs (without protein)            :: 178
            Pseudo Genes (ambiguous residues) :: 0 of 178
            Pseudo Genes (frameshifted)       :: 68 of 178
            Pseudo Genes (incomplete)         :: 118 of 178
            Pseudo Genes (internal stop)      :: 24 of 178
            Pseudo Genes (multiple problems)  :: 32 of 178
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054725.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5596
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP20194f"
                     /serotype="ST11-K64"
                     /isolation_source="telephone of Nurse station"
                     /db_xref="taxon:573"
                     /plasmid="pKP20194f-p5"
                     /geo_loc_name="China: Hunan"
                     /lat_lon="27.72 N 112 E"
                     /collection_date="2019-04-27"
                     /collected_by="Xiaotuan Zhang"
     gene            105..614
                     /locus_tag="HUS08_RS29325"
                     /old_locus_tag="HUS08_29330"
     CDS             105..614
                     /locus_tag="HUS08_RS29325"
                     /old_locus_tag="HUS08_29330"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            621..833
                     /locus_tag="HUS08_RS29330"
                     /old_locus_tag="HUS08_29335"
     CDS             621..833
                     /locus_tag="HUS08_RS29330"
                     /old_locus_tag="HUS08_29335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            1500..1724
                     /locus_tag="HUS08_RS29335"
                     /old_locus_tag="HUS08_29340"
     CDS             1500..1724
                     /locus_tag="HUS08_RS29335"
                     /old_locus_tag="HUS08_29340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            1708..1974
                     /locus_tag="HUS08_RS29340"
                     /old_locus_tag="HUS08_29345"
     CDS             1708..1974
                     /locus_tag="HUS08_RS29340"
                     /old_locus_tag="HUS08_29345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2044..2394)
                     /locus_tag="HUS08_RS29345"
                     /old_locus_tag="HUS08_29350"
     CDS             complement(2044..2394)
                     /locus_tag="HUS08_RS29345"
                     /old_locus_tag="HUS08_29350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197756.1"
                     /translation="MYWLIAFLAFIFPGRSFADGYTAYYRCNGTQEASLTVKDNKLSMV
                     VGLSKFNRQLDTYRFKEKGIEVVMQRAASDDNSEAIMSFIMPDVNNMTLLVKNNGYIIV
                     KTTCWLTKTDKQ"
                     /name="hypothetical protein"
     gene            complement(2460..3005)
                     /locus_tag="HUS08_RS29350"
                     /old_locus_tag="HUS08_29355"
     CDS             complement(2460..3005)
                     /locus_tag="HUS08_RS29350"
                     /old_locus_tag="HUS08_29355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            complement(3031..3357)
                     /locus_tag="HUS08_RS29355"
                     /old_locus_tag="HUS08_29360"
     CDS             complement(3031..3357)
                     /locus_tag="HUS08_RS29355"
                     /old_locus_tag="HUS08_29360"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     gene            complement(3715..3873)
                     /locus_tag="HUS08_RS29900"
     CDS             complement(3715..3873)
                     /locus_tag="HUS08_RS29900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     gene            4513..4689
                     /locus_tag="HUS08_RS29360"
                     /old_locus_tag="HUS08_29365"
     CDS             4513..4689
                     /locus_tag="HUS08_RS29360"
                     /old_locus_tag="HUS08_29365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     gene            4679..5023
                     /locus_tag="HUS08_RS29365"
                     /old_locus_tag="HUS08_29370"
     CDS             4679..5023
                     /locus_tag="HUS08_RS29365"
                     /old_locus_tag="HUS08_29370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062955149.1"
                     /translation="MAVKRTRFLGIRVTDGEYQQLLERCNGRQLAVWMRETCLDTRPAR
                     SLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRVQVVAALMAIDAELERLRHA
                     VLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            complement(5205..5450)
                     /locus_tag="HUS08_RS29695"
     CDS             complement(5205..5450)
                     /locus_tag="HUS08_RS29695"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032433971.1"
                     /translation="MQPQSPVHHGLPRIDARTVCPVVVRLETPAGQQFRVRYQKIQFQP
                     PLVPVFNPQHAVLVFIESGHQNPLEARHQLFTLAGR"
                     /name="hypothetical protein"
     Typing          4348..4427
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="90.361"
                     /coverage="97.0"
                     /evalue="1.1100000000000001e-21"
     Typing          complement(3765..4162)
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          3..949
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.684"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          5014..5594
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="99.0"
                     /evalue="1.2900000000000002e-122"
ORIGIN
        1 ggcgctggaa agcgcaggtt ttgaggtcgt gcgcaccaca aagagcagca tcagcattgc
       61 cgacccggac ggagggcgaa acatccgact taagggagcc atctatgaac agtcttttaa
      121 cgctggcgaa ggacttagag cagaaatcga aagcgcagca gcagagtacc ggcgaaatgc
      181 tgaaagccgc attcagcgag cacgagaagt ctgtcagagc ggaactgagc gaaagcggga
      241 agagaatcag cgccgccatc cgcgcccacg agcagggtat gagcgcggcc atgcagtcga
      301 accgcctgag cgtgatgcgt atggtcgggc ggacatggct gaccatcacg atggtgtcag
      361 gactgctgtt cgccagcctg agcggggtgt tgtggtatca ggggagcttg atagcgtcaa
      421 atctggccga aatcgaccgg cagaacgcag cgctgtcgaa gctgaacgcg aagacctggg
      481 gcgtgacgta cctggaagac agcaacggac gttttctggt gctgccgaag gggacggccg
      541 tagacaggac gcagagctgg acggtcggga acgggcggtc gaagcagaac gcgctgagac
      601 tggtgaagga gtaagtgccg atgaccgagc tggaaaaaca gttgctgagc gcattagagc
      661 agctacagca ggactactcg aaaaggctgg acgagtggga gagcgccttc ggggaatggc
      721 ggaaaatgtc agggcttatg caacgggaga acgcggcgct gagcgagcgc gtgacgcgct
      781 tgagtcagca ggtggaacgc ttgagcgggc aactgcagcg tttgagccgg tagtgcagcg
      841 tcatgagatg gccgtggccg cagaacgggc gcacgagcaa cggcagcacg aaaaggaact
      901 gacggaagcg cgttcccggc agcgaagcta tgacggtccg tcgctgggct gaaatgcagg
      961 aaaacagggt tctcatcggg catttacgct gaaaccggat gtcattcacc tggctgcatg
     1021 gctatgcagc caggtaaaat ttatctgtcg cgaacggggc ggtttatcgg gtggtttgtt
     1081 gccggtttta cctgactgcc accccgttcg cggcgaaccc gtccggggcg gtgcgggcaa
     1141 cgggtgttat gtttaatcag cgtgaacggc agatacaaaa aagccccgga gggcttttaa
     1201 ctactgactt atttttttga agatttgctg ggtttcaatt tgtcagtatt tcccggcgtt
     1261 tttttattgt cacgctggcg tttatcaggt tcccctgttg aatcggcaat tcgtttcgga
     1321 cccggcttaa gacccataat cgttatcctt tcaatagtta agaggaaagc cctcaagcta
     1381 gatatattga ccgcgttacg gattatcaag aggggctaac aagattattt tttgttcttt
     1441 taggttgatt gtggtactgt tgatatacat gtatagcaaa tggtgttcgg gaggtttata
     1501 tgcttgctat ccggttatct gatgagattg agtcccgtct ggactcgctg gcgaagcaaa
     1561 ccggcagaac aaagacgttt tatgcgcggg aagcaatact ggcgcatctg gaagacctgg
     1621 aggattatta tctttcagca gaaactgctg cacgcgttcg ccgtggtgat gaagcagtgc
     1681 attcgtctga agacgtgagg aagtcacttg gtctggacga ttaactattc cgatcgggcg
     1741 ctcaaatcgt tacgcaagat ggacaaacag aacgcacgac ggattgtgga ttttatgagt
     1801 ttacgcattg cagttgctgc cgatcctcgc cagtcaggga agccgctcaa aggtgagctg
     1861 ggcgagttct ggcgctatcg ggtgggagat tatcgcgttc tgtgtgagat ccgagatgac
     1921 gagcttgtta tccttgccgc cacgattgga catcgccgcg aagtttacga ctgaagcccg
     1981 ctatgcgggc ttttttgatg ccgacaacag gtattatggt aaatactcga ctaactacgt
     2041 gttctactgt ttgtcggttt tagttaacca gcaggttgtc ttaacgataa tgtagccgtt
     2101 atttttaact aataaggtca tattgttaac gtcaggcata ataaaagaca ttatggcctc
     2161 agagttatca tcagaagcag ctctctgcat tactacttcg attccctttt ctttgaatct
     2221 ataagtatcc agttgcctat taaacttaga aagacctaca accatactta gtttgttatc
     2281 tttaacagta agagatgctt cctgagtacc attacatcgg tagtaagcgg tgtaaccgtc
     2341 agcaaaagat cgaccgggga atataaatgc taggaacgca attaaccaat acatagttga
     2401 gaatcttggt attacacatt tcactatcct ctctttcatt tttcgttcac catactttgt
     2461 tatctgattt ttaatttttc tattttataa accaagtctc taccaaaaag gcgaaaatta
     2521 tcctcaaata ataataattg tttaagaaca tccatgaaag cagctgcttc accctcagtt
     2581 atgggagcta ctctatataa catataacct gagttaaggg tttcttttat actttcttca
     2641 atgctcatta taaatattag tggattatca tttttcttcc cccatgggtt tctaattaat
     2701 ccttcgatgt actcaggtcc tttgcgtcct attgcctgcg caatattttt tatttcatct
     2761 gcgtgagggc tttgttgtac agctttgttt atgcctgctt gagtgatttt cagagactct
     2821 acaccgtgta tgttgtatga gataaaatgt aataaattaa gatgcaatgc aattaatcca
     2881 tttttgttta catctgagta tttggataaa aaacgtaatg aagtgttaac tctcccttga
     2941 agcctaacaa ttgggagtgc tgccttgtat atttccttct ccgttaaata ccgtttaaaa
     3001 aacataattc tccgcctccg tatagcgtgc ctattttatt tcgtcgtaaa acttagctct
     3061 gaaatattcc tttagaacca tcatgtcatt aataattgaa tctatctcat ccattttttc
     3121 ttggtattct tttaatggtg aagggagcgg taactcaata tttgaaaagt gattggcgag
     3181 atagggatca aggtttctca tccattcagg cttttcgcca atgcgttctt caactgaaag
     3241 tgaacctgat aatctctggt taataagatc acttagactc attttggttt tattcgaaag
     3301 ccgttgtaag gattgcttta atcctatatc tagcatgata tttgttcttt ctctcattac
     3361 ccccccttgc tattgcgttt tttgttgcgc acaaagctac cattgcgcat taagaaacgc
     3421 aataaaaaag gagggaggga gtggtttgta catgatgtgc agtgcgctga gggcatcagt
     3481 ggcgggtgtt tttccgtggg atggatggag ctccggggat aacagaactg acgatcattt
     3541 aaaggatctt cttgagatcc tttttttctg cgcgtaatct cttgcactgt aaacgaaaaa
     3601 accgcctagg gaggcggttt gatcgaaggt taagtcagtt ggggaactgc ttaaccgggt
     3661 aactgggtat acgagaccgc agataccaaa actgttcttt cagtgtagcc gcagttaggc
     3721 acccacttca agacctctca atatctctct cgtatatatc cagttaccaa tggctgctgc
     3781 cagtggcgtt tttgcgtgtc cgtccgggtt ggactcaaga tgatagttac cggaaagggc
     3841 gcagcagtcg ggctgaacgg ggggttcgtg catacagccc agcttggagc gaacgaccta
     3901 aaccgagccg agataccagc agcgtgagct atgagaaagc gccacgcttc ccgaaaggga
     3961 aaaaggcgga acaggtatcc ggtaaacggc agggtcggaa caggagagcg cacgagggag
     4021 ccgccggaga gaaatcaccg gcatctttaa gtcctgtcgg gtttcgtcct cctctgactt
     4081 gagcgtccat ttctgtgatg ctcgtcaggg gaggcggagc ctatggaaaa acggcaacgc
     4141 cgcatccttt tctccggccc tttctgattt gagcgccttt gctttatccc gttatccgtg
     4201 agtcggtcac gcccgccgca gccgaacggc aggagcgcag ctaccgagtg agcgaggagg
     4261 cgtcatttca tctgtccgtg catggtattg cggacgctcc tgagccacat atcacacctg
     4321 ccacatgagg cactttcatg aatcgtgctc tcatgccaac atagtaagcc agtatacaca
     4381 gcgtaaacgc tgtgactggt tcagggctgc gccccgaaac ccgctaacac cactgacgcg
     4441 ctggcgcttg tccaacgccg gagcgacccg gaaaactttt ccgtgccgtc cggcgtttgc
     4501 gaaggaggga taatgcagaa gccgaagaag aagccgctcg tcgtaaaaaa aagatcctgg
     4561 catccggcag tgatggcaaa tctgatgcgt caggcacagg aggaagatta ccgccgggag
     4621 cagatggcag agcttgagcg ttcagcccgg tcacattttg cggatatcgg aggagaggat
     4681 ggcggttaag cgtacccgtt ttttaggtat ccgggtgacc gatggggagt accagcagct
     4741 gctggagcgc tgcaatggaa ggcaactggc ggtgtggatg cgggaaacct gtctcgatac
     4801 gcgcccggcg cggtcgttgc ggctgccgtc catcgatccg gttttgctgc gccagcttgc
     4861 cgggatgggg aacaacctca accagatcgc ccggaaaatt aacggcggcc agtggtcagg
     4921 cgctgaccgg gttcaggtgg tggccgcgct gatggccatt gatgccgaac tcgagcggct
     4981 gcggcatgcc gtgctggaaa agggggcaga cgatgatcgt taagtttcat ccgcgagggc
     5041 gaggcggcgg tgccgggccg gtggattatc tgctggggaa agaccgccag cgcgacgggg
     5101 ccatcgtcct gcagggaaag ccggaggagg tccgggagct tatcgacgcc tcgccctacg
     5161 ccaaaaagta cacctccggc gtcctgtctt ttgctgaaca ggatttaccg cccggccagc
     5221 gtgaaaagct gatggcgagc ttcgagcggg ttctgatgcc cggactcgat aaagaccagt
     5281 acagcgtgct gtgggttgaa caccgggaca aggggcggct ggaactgaat tttctggtac
     5341 cgaacacgga actgctgacc ggcaggcgtc tccagccgta ctacgaccgg gcagaccgtc
     5401 cgcgcatcga tgcgtggcag accgtggtga acgggcgact ggggctgcac gacccgaacg
     5461 caccggagaa ccggcgcgcg ctggtgacgc catcttcgtt acccaaaacg aagcaggaag
     5521 ccgcagaggc tattacgcgg ggcttactgg ccctcgcctc gtcaggggag cttaaaacgc
     5581 gtcaggacgt cactga
//
