LOCUS       NZ_CP054577            29715 bp    DNA     circular CON 12-SEP-2023
DEFINITION  Staphylococcus saprophyticus strain UTI-050 plasmid pUTI-050-2,
            complete sequence.
ACCESSION   NZ_CP054577
VERSION     NZ_CP054577.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15089828
            Assembly: GCF_013343055.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus saprophyticus
  ORGANISM  Staphylococcus saprophyticus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 29715)
  AUTHORS   Stephens,C., Wright,M., Hartman,A., Gonzales,A., Sensabaugh,G.,
            Robinson,P., Lopez,G. and Hess,D.
  TITLE     Complete genome sequences of diverse uropathogenic Staphylococcus
            saprophyticus isolates from a college health center
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 29715)
  AUTHORS   Stephens,C., Wright,M., Hartman,A., Gonzales,A., Sensabaugh,G.,
            Robinson,P., Lopez,G. and Hess,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUN-2020) Biology, Santa Clara University, 500 El
            Camino Real, Santa Clara, CA 95054, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 168x
            Sequencing Technology :: Illumina MiSeq, Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/12/2023 03:38:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,706
            CDSs (total)                      :: 2,621
            Genes (coding)                    :: 2,541
            CDSs (with protein)               :: 2,541
            Genes (RNA)                       :: 85
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 42 of 80
            Pseudo Genes (incomplete)         :: 33 of 80
            Pseudo Genes (internal stop)      :: 23 of 80
            Pseudo Genes (multiple problems)  :: 16 of 80
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054577.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..29715
                     /organism="Staphylococcus saprophyticus"
                     /mol_type="genomic DNA"
                     /strain="UTI-050"
                     /isolation_source="urine specimens"
                     /host="Homo sapiens"
                     /db_xref="taxon:29385"
                     /plasmid="pUTI-050-2"
                     /geo_loc_name="USA: California"
                     /collection_date="2019"
     gene            complement(join(28857..29715,1..998))
                     /locus_tag="HSZ50_RS13155"
                     /old_locus_tag="HSZ50_13175"
     CDS             complement(join(28857..29715,1..998))
                     /locus_tag="HSZ50_RS13155"
                     /old_locus_tag="HSZ50_13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002511755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_241158948.1"
                     /translation="MTSTPSVEAKDKADLNIETHSNSENTLEQRIQEGKEKIDKLKNIK
                     DSQKDASIKEITKAKSTEEVEAILKKAKKVDNKIIEQNRVQSHLIENDKKEVSEDKKSV
                     KSELDSKKNIVSSVKEKSNHIEEQDSIDLFDQEDLQDNTFDANLNQRDTKQDISHLVDM
                     GKLNEESKDIADMNDSEENKNTASEKDEGAVKENNQDGLAFKDTSNTKSNQMQQSDEIK
                     KDIDKVTTNHSKVKDNLDYYVENKENNLKILDSKLSERDSISAKNKEKLKKEIEKTQQS
                     LKKQNDVVLNHLQSVNNKEQAVKDIVSGTFDEKSAQSILERIDTKGKTDQQIASQVVSE
                     LDNLSTTTSDDILKSMFDKTSDKQELIKTILLTKFDHIDTSKIVDEIMHKNPSNEQIVA
                     LIKHHFGDNVTSDDILENILDQSHDKRKALETMLATKLNDAKAKALADVIAKKEDSKHN
                     LLNLMKSGINNELNDLLKADKDISKFKDDMHGLFEPLKYTPSLSNKFDGSLLDRAEQMR
                     KLSGNSKLLGTPSLFDDLFNRNSILDGIKDISNPSPGRALSLGDSSGSFLSGLFDNNGD
                     FSLPDTGTVVKKSTIPLGILLFIIGGGLIWFIKRNKSKNCKY"
                     /name="hypothetical protein"
     gene            <1245..1501
                     /locus_tag="HSZ50_RS13160"
                     /old_locus_tag="HSZ50_13180"
                     /pseudo=""
     CDS             <1245..1501
                     /locus_tag="HSZ50_RS13160"
                     /old_locus_tag="HSZ50_13180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002432347.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="butanediol dehydrogenase"
                     /name="butanediol dehydrogenase"
     gene            complement(1626..2000)
                     /locus_tag="HSZ50_RS13165"
                     /old_locus_tag="HSZ50_13185"
     CDS             complement(1626..2000)
                     /locus_tag="HSZ50_RS13165"
                     /old_locus_tag="HSZ50_13185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_011304037.1"
                     /translation="MINEMEELNQVKLDLKKLRNKFPNMYEKLEYIASLTRQLSIHYKY
                     LGLLMFSDNREIIQNKRPTLIRESVLKLYEQEVKKVKKDSNFVIFKDMMLKFQNVNYSQ
                     IFLIILGAEPSFVFKNTIIK"
                     /name="hypothetical protein"
     gene            complement(2008..2532)
                     /locus_tag="HSZ50_RS13170"
                     /old_locus_tag="HSZ50_13190"
     CDS             complement(2008..2532)
                     /locus_tag="HSZ50_RS13170"
                     /old_locus_tag="HSZ50_13190"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011304038.1"
                     /GO_function="GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_011304038.1"
                     /translation="MENYKFPSDSKIVSTDQVLINDLNNYNTLFGGVLMKKIDNNATLS
                     ARRHARVKECVTASTDSVEFLYPITQSDSVCIESYVVYTGEKSMEIFCKVISEDMITAE
                     RKIAAVAFLTFVALDEKKKPIKVPKISPQSKEEKLLFMDGEERAKMRKIKRSQTKNIIE
                     SLDINKPWELE"
                     /name="acyl-CoA thioesterase"
     gene            complement(2642..3529)
                     /locus_tag="HSZ50_RS13175"
                     /old_locus_tag="HSZ50_13195"
     CDS             complement(2642..3529)
                     /locus_tag="HSZ50_RS13175"
                     /old_locus_tag="HSZ50_13195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_011304039.1"
                     /translation="MELRHMQYFVEVVKQKSMTKAASNLFITQPTISNTIKLLEEELDV
                     NLFNRYKNQIYLTDAGEAFFFQCKEMLKMYDNIPNELSNLLELKKGHLKIGIPTIINIR
                     RLIGLISEFHEMYPNITFQLFENGSKKIENDVYYGDLDMGITVLPTNNKNFDIFSFLEE
                     KLKLVVHKNHELSKKTKIDIEDLQEQEFILFNSDFYLNDKIKNTCRNYGFNPNIIFETT
                     QWSFIEEMLLNNLGICILPEGILGLLDNNLQAIDINEPSMKWELGIIWRKDIIVDSLTK
                     NWIKFLQENFLINY"
                     /name="LysR family transcriptional regulator"
     gene            complement(3578..4129)
                     /locus_tag="HSZ50_RS13180"
                     /old_locus_tag="HSZ50_13200"
     CDS             complement(3578..4129)
                     /locus_tag="HSZ50_RS13180"
                     /old_locus_tag="HSZ50_13200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508682.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_011304040.1"
                     /translation="MAKIGYARVSTQDQSLDGQIDTLKDYGCERIFSEKVSGRKTKRTE
                     LDKCLDYLREGDILVIYKLDRLGRTTKQLIDLSQWLDENGIDLHIIDMNVSTKDAMGKM
                     FFTMMSAFAELEANLLSERTKKGLEAARARGRKGGRPSLPDYKKREIKFLYDEQKLTGE
                     EIAKQTDVSRSTVYRIIKNN"
                     /name="recombinase family protein"
     gene            complement(4400..5914)
                     /locus_tag="HSZ50_RS13185"
                     /old_locus_tag="HSZ50_13205"
     CDS             complement(4400..5914)
                     /locus_tag="HSZ50_RS13185"
                     /old_locus_tag="HSZ50_13205"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF020877.3"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="WP_069794937.1"
                     /translation="MKKIYLLINSLELERGGLTKANLQQASMFSELGYETYILTFNYNS
                     DYNGIIEDIYDVYKVNKKVKIINMYDYFRNEDQIDQKFKSYKNLINDDSIVEKNDSKDI
                     VKIYENGLYKKNISYRSDESIKKIDYFNNSNYRIKVEFYAPEGYIGKLSYMDYNLNRPR
                     QMTFYNSIGNCYLRKTVNPENGLATKVDLIKKGQIVHSFRSDRQLKSYFVEQIVNNNKD
                     SVIISDARNTDDIMINIKNENSSKNVRLHSNHLSPNGEIAKTVMTSLENLKNIDSLIVL
                     TSQQKEDIVNNYGYSEKVKVIPHGIQTLPSKDINNIIRKNKAVVISRLVKLKQIDHIIK
                     AMQLIKDDDPDFILEIYGNGNELENLKSLVKKNKLENNIIFKGYTNNPLEIYNESLFSI
                     TTSKSEGFSLSILESMASGTPVISYDFKYGPEEIIDNNKNGLVINKDNIKELAEKILYL
                     KNNEKVLKDMSEKSIEKIEEKFSIQSVKKKWFEFIENNNITNPNNL"
                     /name="glycosyltransferase"
     gene            6073..9261
                     /locus_tag="HSZ50_RS13190"
                     /old_locus_tag="HSZ50_13210"
     CDS             6073..9261
                     /locus_tag="HSZ50_RS13190"
                     /old_locus_tag="HSZ50_13210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016930563.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0047355 - CDP-glycerol
                     glycerophosphotransferase activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="WP_069794936.1"
                     /translation="MLHIKQEGTVLYISFGEPKENITGLYVKNSFKSIFYKSYDESFNF
                     KIDLNEVLDIFKEFNETKIFLTLGVLENKRKKQKNIEVTNEYTSIYNLEKVSDGVNTIY
                     PYITKNGFLHFTMTNYTPLKAFFSRRHIDKLKFNNHQALIEGQFSIINSTIQKASLVLT
                     TRFTDRELEVYLPSTVDSKNKNTSTFNFSVDIYNELIKFMKHSFIIGDVIDIYLKIDIQ
                     ESFVPLKIKIGNPRVLIERFLKGEIITDYQNDIISITPYFTMKGRNLSFRINRYTIDSY
                     LTYIENFKKTNVKLPFQKNRPKVWVVGEKSYKAQDNGFHFFKYMRTHHPELPVYYIIEE
                     DSNEIQNVLPFGNVIYYKSPEHFKIMLQADYICTTHHPELIFPTNSVIYTKKIKATRVF
                     LQHGVLGTKNLSNINGNQLKDFNVDLFITSSEREKQIVVRDLKFDSSQVAVTGLARFDN
                     LFNPKVTTKNQVLIIPTWRDWLINIEQIEYSEYLKRINQLLNSSNIKNIVNDGNEVIFC
                     LHPNMQPFIDSFNVPSYITSIKQGDVDVQKLIQESKLMITDYSSVAFDFSFLNKPVIYY
                     QFDKDKFLGKQPSHIDIENELPGTIVNNQQDLEKQLKKMIMNNYQIDKNVEMKANQFIK
                     YHDQYNSQRIFEAVQKSKTTNRLKRKFKYDILTQHLFKRFRKSKKYFNVMDKYNSAISK
                     VVPVKKDLVVFESNVGKSVSDSPKVIYDKLKEYSDAYQIVWVSNPQFPFNDPNVIRVKR
                     LSPEYYHYLSRAKYWVNNQNFPHYITKPKDTIYIQTWHGTPLKKMLNDVESFEGRDANY
                     KNRVNNAIKHWDYLVSPSPYASRCFRSAFEFQKEILEVGYPRNDIFYNEDIVYINNKKE
                     KIKQRLGIQDERKIILYAPTFRDDEVNKAKKHIINLQIDLQQMKEKLSKDYILILRPHI
                     IISNSLQLDSSLDNFVINGNKYNDISDLFLITDICITDYSSVMFDFANTKKPMLFFTYD
                     LEHYRDSLRGFYFDFENEAPGPLIKTNDSLIKSIENIEQIQQQYQMKYEKFYDKFCSYE
                     KGTAAQSIIHNFFK"
                     /name="CDP-glycerol glycerophosphotransferase family
                     protein"
     gene            complement(9497..9697)
                     /locus_tag="HSZ50_RS13195"
                     /old_locus_tag="HSZ50_13215"
     CDS             complement(9497..9697)
                     /locus_tag="HSZ50_RS13195"
                     /old_locus_tag="HSZ50_13215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002448025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002448025.1"
                     /translation="MAGFLDNIDTSEVKYTENYRPISKSTTMRVDTDIKKRLNQMALDK
                     DTSIKSIIDKVLEEFLENNKY"
                     /name="hypothetical protein"
     gene            complement(9703..10497)
                     /locus_tag="HSZ50_RS13200"
                     /old_locus_tag="HSZ50_13220"
     CDS             complement(9703..10497)
                     /locus_tag="HSZ50_RS13200"
                     /old_locus_tag="HSZ50_13220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366803.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_002448023.1"
                     /translation="MNIITVGNFKGGVGKTTVSTLLSYIASENYNKKVLLIDFDPQGNA
                     TQIMKRTYPEFKEESLSFINMLKSGNIDESIIRLTSNLSLLPADSSLANLSDIISKTDI
                     LKKRYILKNVVEKIEKIYDFDYVFIDVPPTINSDFTNNAVYASNYILMVFQTQQSAYES
                     SLSFVNFLRDRKKESDLPFELVGAVPVLIKKNGRVDKQILEMSKSAFSEALFEHQIYQR
                     ERIKKFAADGIKDKDMHDKKVIHMFNKVYEELVSRIKLIEEE"
                     /name="ParA family protein"
     gene            11139..12404
                     /locus_tag="HSZ50_RS13205"
                     /old_locus_tag="HSZ50_13225"
     CDS             11139..12404
                     /locus_tag="HSZ50_RS13205"
                     /old_locus_tag="HSZ50_13225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_011304047.1"
                     /translation="MTNEENQKFTKLHKFLFTDNKFKAMRAKSKLLYAIITERQSLTIA
                     YAKNNQDQSQFLDENKRLFSIYSNSDLKGMLHVSEPTIINLKKELIEYGLLEEIRVPTS
                     NNRLYPKKPYDKYYYLNDIDEFYRLPYALFDNPFYNKLSPDAIITYAIYLSRYEYSVFK
                     DIFYDKTHNIYCVMPNQEIAKFLNINRKKVARLKNELIAYGLIEVKPSKRADKLYVNPP
                     KQRNDNKLKKWDIANLKNGTLQTKDMGHCKLKKWDASYTDFSNTNISVIDSNDMNDMND
                     IREANIEDTKPNQPNHTDHLQKQSDEEALKHLELQEMPEDTKRYMNNFSAKEIQIIKSV
                     ILKAKRSFNDLYGEVYMLEDMDDELFTVLKRFKGIMVKKQEKLENMQGYLMRSILSELE
                     EMRSTNMRRKNFENSPLNVFKS"
                     /name="replication initiator protein A"
     gene            12424..13047
                     /locus_tag="HSZ50_RS13210"
                     /old_locus_tag="HSZ50_13230"
     CDS             12424..13047
                     /locus_tag="HSZ50_RS13210"
                     /old_locus_tag="HSZ50_13230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_011304048.1"
                     /translation="MIGYEFFVSEKLENCKYKYIKAINDYIKQEKSHIIGIDLGKYHYL
                     TASNIDRSFVFVDKHNTLFHLFRKYERRIANKQYDNSEAYSKLKTGLKSHINQVVNEML
                     EQTSNRFQTVFALDDHGSSHLSFPSLVFDLTYFAIKQRKNESDEILIVDESFTSIECPI
                     CHDRNQYNRTNKNKFKCTKCGFIHQNNDIVAASNIAKKGQLLNS"
                     /name="zinc ribbon domain-containing protein"
     gene            13068..13343
                     /locus_tag="HSZ50_RS13215"
                     /old_locus_tag="HSZ50_13235"
     CDS             13068..13343
                     /locus_tag="HSZ50_RS13215"
                     /old_locus_tag="HSZ50_13235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_153907253.1"
                     /translation="MNNKQKARLKHYKNYDYPKQAYAFFDHKKVKVVLNNGESFTGYIV
                     KEYTYEILLVKSDGIKDPKDNELEKRTLIPKHSIAYTTNFIHLPQE"
                     /name="hypothetical protein"
     gene            14045..14719
                     /locus_tag="HSZ50_RS13220"
                     /old_locus_tag="HSZ50_13240"
     CDS             14045..14719
                     /locus_tag="HSZ50_RS13220"
                     /old_locus_tag="HSZ50_13240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_174605061.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRNTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCQEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(14942..15211)
                     /locus_tag="HSZ50_RS13225"
                     /old_locus_tag="HSZ50_13245"
     CDS             complement(14942..15211)
                     /locus_tag="HSZ50_RS13225"
                     /old_locus_tag="HSZ50_13245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508598.1"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_011304050.1"
                     /translation="MAKLNITFSPQAFEDYEYFQLKDRPMVKRINKLLKSINRDGALGG
                     IGKPEKLVGSLSGYYSRRINQEHRLVYTVNDTSIMVASCRYHYR"
                     /name="Txe/YoeB family addiction module toxin"
     gene            complement(15212..15460)
                     /locus_tag="HSZ50_RS13230"
                     /old_locus_tag="HSZ50_13250"
     CDS             complement(15212..15460)
                     /locus_tag="HSZ50_RS13230"
                     /old_locus_tag="HSZ50_13250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608026.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0097351 - toxin sequestering activity [Evidence IEA]"
                     /GO_process="GO:0045927 - positive regulation of growth
                     [Evidence IEA]; GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_011304051.1"
                     /translation="MTVKNYTFVRDNFRDMINKVNDDSDTITITTKDRNAVLMSEDDYD
                     AIMETLYLQQNPSNAKHLAESIENLERGNVKSKEIEI"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            complement(15768..16766)
                     /locus_tag="HSZ50_RS13235"
                     /old_locus_tag="HSZ50_13255"
     CDS             complement(15768..16766)
                     /locus_tag="HSZ50_RS13235"
                     /old_locus_tag="HSZ50_13255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011304053.1"
                     /GO_function="GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_041785008.1"
                     /translation="MERYNRQVRYHQFGEYGQSQLQKTHVMIMGAGALGSHSAEMLVRM
                     GVGSLTVIDMDIVELSNLHRQALYDELDAEKMLPKVEALKHKLNQINSNVQVIAIDREI
                     TNLNIENLLSTYHPDIVIDGMDHFKIRYLINESCNKQNIPWIYGAAVGSKGTVYGIDDQ
                     GPCLKCLLETMPSTGESCAINGVLPPVIYQVASIQVSELMRWVSGEAFSKKLITIDCFN
                     MQYKSMDVNALKQSDCNVCKKHEYALLNDKYDNKIEKQCGDMFLLRFNADIFSHTDYLP
                     VTVKKANNFVKLLSYKPYEITLFKDGRMHVYGVENEGEAEKIYREIGKSLS"
                     /name="ThiF family adenylyltransferase"
     gene            complement(16766..17533)
                     /locus_tag="HSZ50_RS13240"
                     /old_locus_tag="HSZ50_13260"
     CDS             complement(16766..17533)
                     /locus_tag="HSZ50_RS13240"
                     /old_locus_tag="HSZ50_13260"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015901320.1"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="WP_011304054.1"
                     /translation="MFKIGNFTLNSRLLLGTGKFDNEEIQTQAIAAAETEVLTFAVRRM
                     NLYDKDLPNPLAKVDLSKFITFPNTAGAKTAKEAVRIAEIANHAGVCDMIKVEVIGDDE
                     TLLPDPLETYEACKVLLEKGYTVCPYISNDVVLAKRLEELGVHAIMPLASPIGTGRGIN
                     NPLNLRYIIERVNVPVIVDAGIGSPKDACHAMELGADGILLNTAISSAADPVKMAEAMN
                     KGISAGRLSYEAGRIPVKYTAQASSPTEGIGFL"
                     /name="thiazole synthase"
     gene            complement(17535..17735)
                     /gene="thiS"
                     /locus_tag="HSZ50_RS13245"
                     /old_locus_tag="HSZ50_13265"
     CDS             complement(17535..17735)
                     /gene="thiS"
                     /locus_tag="HSZ50_RS13245"
                     /old_locus_tag="HSZ50_13265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011304055.1"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_011304055.1"
                     /translation="MKCKINGDVFNFEQPINIQEIIQSLGLDETRIIVEHNETLIKREQ
                     FTSRIVNDEDNLELLEFVGGG"
                     /name="thiS"
     gene            complement(17725..18837)
                     /locus_tag="HSZ50_RS13250"
                     /old_locus_tag="HSZ50_13270"
     CDS             complement(17725..18837)
                     /locus_tag="HSZ50_RS13250"
                     /old_locus_tag="HSZ50_13270"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002506451.1"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA];
                     GO:0016491 - oxidoreductase activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_011304056.1"
                     /translation="MYDVIIIGSGVMGMSIARGLSQSFANIAVIDRDEAGKHASYKAGG
                     MLGAQNEFTKNSALFSLATTSQKMFKPLRDSLLEEVGVDIEYLNSGLIKLATNHYDNKK
                     IEQQYQFLRQHFASVERLSPTDVQHMSNGAITSKHTNGIYMPEDNQINANRYTKGLLKS
                     LSNRHIDRIYQTTVTHIESIKDGYRVETRNGAYYTEKLIVTGGAWTGKLLQQYLPCETV
                     IGVKGEALLVEQPDLNLNITMFLTNGCYVIPKLKNRYLIGATSYFNDYSVGVSNSGKSW
                     LKSQALHYIPDLKNGKIINQWSGIRPYCQNEQPIMDEVDKDLFVIAGHYRNGILLSPLI
                     GELMSQWIISGHRPKQLYDFQIRRGERNEM"
                     /name="FAD-dependent oxidoreductase"
     gene            complement(18830..19414)
                     /locus_tag="HSZ50_RS13255"
                     /old_locus_tag="HSZ50_13275"
     CDS             complement(18830..19414)
                     /locus_tag="HSZ50_RS13255"
                     /old_locus_tag="HSZ50_13275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017723966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_041785010.1"
                     /translation="MFIAITPYQDLSKSHIKHYCEIEGVIDYLLIRVPMNTEEVIQWVH
                     GLLKNEFPKDKIIVHSDINVIIQCDLSAIHFRESDPYIEEVQASYPDMQISMSTHHKDA
                     IANAKYLGLDFVLFGHVFETSSKPQQTPRAKSEVEEALQIDIPIIAIGGINQHTLSSLP
                     NGFSGIAGISVFNQYSKEKLINMKEVWDGHV"
                     /name="thiamine phosphate synthase"
     regulatory      complement(19483..19592)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /name=""
     gene            complement(19729..21216)
                     /gene="xylB"
                     /locus_tag="HSZ50_RS13260"
                     /old_locus_tag="HSZ50_13280"
     CDS             complement(19729..21216)
                     /gene="xylB"
                     /locus_tag="HSZ50_RS13260"
                     /old_locus_tag="HSZ50_13280"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017723967.1"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA];
                     GO:0004856 - xylulokinase activity [Evidence IEA]"
                     /GO_process="GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]; GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="WP_103314675.1"
                     /translation="MNEAVLGIDIGTSSVKVIAVSKEGEVLAKVSEGLDIIQLQSGCNE
                     QQPDEWFEATKSCIRQILSASALSDIYIRGLSLSGQMHSLVVLDSTNKPLRNAILWNDT
                     RSTHQCTTIEQQFGDYILSNPVLEGFTLTKLLWIKDNEPNNWNKIATFLLPKDYVRFKL
                     TGKINMEYSDASSTLLLDPKQKSWSKTTGSQFRIHDIYPSLVSSGDFIGYVESSLAKSL
                     GLTGEVAVFAGGGDNACGALGAGVIKSNDTLCSIGTSGTLLTCESGEGKTYRHNLHYFN
                     HVVEDKSYVMGVTLAAGDSLNWLKKHVFPGLTFNQILSLASNSTIGSEGLLFAPYLSGE
                     RTPHGDSQIRGSFIGLSTLHTNADIARSVIEGITYSLYETLVHLREQGKDITHITSIGG
                     GARNDFWLQLQADIFNAKVSKLKYEEGPCMGAAMLAIVGLSWYESLEDVVDQFIVYDRT
                     FLPNEVHHERYVKYFEIYQEVYRQTRPITARLLELSL"
                     /name="xylB"
     gene            21383..22057
                     /locus_tag="HSZ50_RS13265"
                     /old_locus_tag="HSZ50_13285"
     CDS             21383..22057
                     /locus_tag="HSZ50_RS13265"
                     /old_locus_tag="HSZ50_13285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_011304059.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILSERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPGCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(22248..>22550)
                     /locus_tag="HSZ50_RS13270"
                     /old_locus_tag="HSZ50_13290"
                     /pseudo=""
     CDS             complement(22248..>22550)
                     /locus_tag="HSZ50_RS13270"
                     /old_locus_tag="HSZ50_13290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834869.1"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine 5'-phosphate decarboxylase / HUMPS
                     family protein"
                     /name="orotidine 5'-phosphate decarboxylase / HUMPS family
                     protein"
     gene            <22560..22760
                     /locus_tag="HSZ50_RS13275"
                     /old_locus_tag="HSZ50_13295"
                     /pseudo=""
     CDS             <22560..22760
                     /locus_tag="HSZ50_RS13275"
                     /old_locus_tag="HSZ50_13295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001798878.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /name="winged helix-turn-helix transcriptional regulator"
     gene            complement(22965..23420)
                     /locus_tag="HSZ50_RS13280"
                     /old_locus_tag="HSZ50_13300"
     CDS             complement(22965..23420)
                     /locus_tag="HSZ50_RS13280"
                     /old_locus_tag="HSZ50_13300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483600.1"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_011304031.1"
                     /translation="MEHKEGNLEIIINQFYDATANINKAITNMVKELEPGRYLSYEQIE
                     TMYFIQHNEKVSINDLANKQRTYKTAASKRVKKLESKGYVQRVYSNDKRTKLLSLTHNG
                     ERLLKEMKINLTKEIKLLLLSCFVREDFEKFMYQLMNFEKTFLKKYY"
                     /name="MarR family transcriptional regulator"
     gene            complement(23506..26355)
                     /locus_tag="HSZ50_RS13285"
                     /old_locus_tag="HSZ50_13305"
     CDS             complement(23506..26355)
                     /locus_tag="HSZ50_RS13285"
                     /old_locus_tag="HSZ50_13305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834639.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="WP_011304032.1"
                     /translation="MKNAIKLFVMDLKKIAKTPAVLVILGGLALLPSFYAWFNLEATWD
                     PYGNTKNIKVAVVNEDKGDTVKDKNVNVGNKITNKLKKDDNFDWQFVSRKKADHDLKMG
                     DYYAAIYIPEKFTHQITGTLRKNPQQADVEYKVNQKLNAIAPKMTNAGTSAIVQKANEQ
                     FNETVTKALLDEANRLGVKLEEEIPTINKIEDAVSKANDSIPKINDFADKIIYLDENQD
                     EIDNYADEFRALGNHKGEVIDAADKLNQVNAAIPTLNERAKLILALNDYMPNIENALNV
                     ASNDVPEAFPKINRGVDLASAGVDAGLQGLNEAQGYLPAVQQRVEGYQEVVDNAQEANQ
                     NANNRLQENVETEQQSSKGSDSYSNIKTSQISNSNSDNAGNNQNGTAISSEDVSAMESS
                     LSKSLLSLSNYTDKQAESSQEDINALKNVTYGIISTDKPKDFKETLDNIKSRLEVTSKS
                     NQKFIDILSELEDREKVDLSDEIKELESANNRINNLIKTQNQLSEALSNGSSGKEEAVE
                     LLKEIPRVNSSLDDLRNYIKSELNQKLLDVSNDVMSLLDDGDIKLSTVQSKLNTIDQVI
                     NSGESILTTGKDRVETIQSALPVIEQRYMDAMSIAQNYYPQFKQSVSNAASFIENDLPG
                     LEQQLSDTTATVNNTIPTLFNRYDNLVDILDTNQPRAKESLHNLADFARNQLPDVEKDL
                     AKANKLFDEIEDDDAVDKMVDLLKNDLKKQANVIANPINIDQKDIFPVKDYGSASTPFY
                     TALAIWVGALLLVSLLTTDNKHKSLEPHLTTREIYLGKSGLFYTLGIIQALIVSIGDMV
                     ILKAQVESVVWFIAISVFSSLVFISIVYTLVSLLGNPGKAIAIIFLVLQIAGGGGTFPI
                     QVTPEFFQVIHPYLPFSYSIDALREAVGGPVPEILTKKLVILSLFGIGFLLIGVIFKPI
                     TDPLMRKATEKAEESDVME"
                     /name="YhgE/Pip domain-containing protein"
     gene            26574..28691
                     /locus_tag="HSZ50_RS13290"
                     /old_locus_tag="HSZ50_13310"
     CDS             26574..28691
                     /locus_tag="HSZ50_RS13290"
                     /old_locus_tag="HSZ50_13310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011304033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="WP_063489142.1"
                     /translation="MKQQKLLVCLLSTSLLIPSFSINDVSAESLEKSATTSESNDVYKE
                     KDEEQAKQSHSSKNGNDEKNKASDEKENSERKSKLNSTKDERTTEDINNKRHKTSDNKS
                     SNEKIPSSFENSFNDSSSYDSLNVFKPEPFRSDKDGLSELLNQLFSNNKMKQTSTIENN
                     DVQNEKNDSHNDNTSIDQINPNTTYSDDSDESNTNNLEKNSDKGSLQDDIDDVQSSEKS
                     ENDDIDNKSESNKLPVDKNQKKDDGESKQSSQQDQSYEEANNDADNLDNKDNDTPATEN
                     DNANSDNENADKSDTKSDDKVLDAILDEYSEDAKNNKKQYDAQKDDLSNGNSKSKKNNS
                     EKQASNTNANPQLPSESQLAKKEKPAQSFENDINQSNIRSTATFQQLPNLSDDNNNSND
                     ITITESKNTRDFIKTVAQDAHDIGQDEDIYASVMIAQAILESDSGTSDLASSPHFNLFG
                     IKGAYEGQSATFNTLEDNGNHTFQISANFRSYPSKKESLEDYANLIKHGIDGNQDIYKP
                     TWKSEAYSYRSATMHLATTYATDSQYADKLNSIINHYDLTQFDNKKMPDLDNYKANNDD
                     YDSAFKPFSETTNDSPYPHGQCTWYVYNRMAQFDKYVSGDLGDARNWNNRAERKDYAVS
                     STPKAHTAVVFEAGQQGADQIYGHVAFVEKVNDDGSIVISESNIKGLGIVSYRTIDADA
                     ATELSYITGNN"
                     /name="amidase domain-containing protein"
     Typing          11140..12404
                     /name="rep_cluster_2442"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atttgttgat ctgttttacc ttttgtatct atacgttcta aaatagattg tgcactcttt
       61 tcatcaaaag taccactaac aatatctttt acagcttgtt ctttattatt tacagattgt
      121 aaatgattta atacaacgtc attttgtttt tttagacttt gttgcgtttt ttctatttcc
      181 tttttcaatt tttctttgtt tttagcagat attgagtctc gttcagaaag ctttgaatcc
      241 aatatcttta aattattttc tttattttcg acataataat ctaaattatc ttttactttt
      301 gaatggtttg tcgtaacttt atcgatgtct tttttaattt cgtctgattg ttgcatttga
      361 ttactcttag tattagatgt atctttaaat gctaaaccgt cttggttgtt ttctttaaca
      421 gcgccttcgt ctttttctga agccgtattt ttattttctt cactatcatt catatctgct
      481 atatctttac tttcttcatt tagtttaccc atatcaacta aatgagatat atcttgcttt
      541 gtatctcttt gatttaaatt agcatcaaac gtattatctt gcagatcttc ttgatcgaac
      601 aagtcaatac tatcttgttc ttcaatatgg ttagactttt ctttaacaga agaaactata
      661 ttttttttac tatctaactc acttttcaca cttttcttat cttcagatac ttcctttttg
      721 tcattttcaa ttaaatgact ctgcactcta ttctgttcaa tgattttatt atcaactttt
      781 tttgctttct tcaatattgc ttcaacttct tctgtgcttt tagcttttgt aatttcttta
      841 atagaagcat ctttctgact atctttgatg ttttttaatt tatcaatttt ctctttacct
      901 tcttgaatgc gttgttctag cgtattttca ctattcgaat gcgtctcaat atttaaatca
      961 gccttatctt ttgcttctac tgatggtgtc gaagtcatac tataccccat caaagaagtg
     1021 ctaataatga gtgccatagt agaaaattta aattgatgat ttaatctggt tttattactt
     1081 aaattattat accttaactt tttcattaaa ttcacctttc ttctaattat tcatcctcat
     1141 tatataggtt atataacttt attcaaatag caatattgct atactatatc attaaaaaat
     1201 aaattttatg tccaaattta ttgataaatc aacttatatt taaaactgtc gttatagtgt
     1261 ctatatttgg tcatcctatt gaatggaatc caatgcaatt aacaaataca ggtgtaaagc
     1321 tcacttcgac aattgcttat acacctacta catttcaaaa acaatagatt taattaatga
     1381 aggtaattta aaagttaaag atgttattac tgatgagata gagctagatg atattgtcga
     1441 atcaggattt gaaaaactca taaacgataa atcacaagca aaaattctca ttaagttata
     1501 aaaattaata aaagagcctc tctaaattta gggaagctct tttattagct aaaatatagt
     1561 tttatttagt caagaaattt gtgagttttt ataattcatt aatctaggga ttgttaataa
     1621 agttattatt taataattgt atttttaaat acaaaactag gttcggcacc taaaataata
     1681 agaaatattt gtgagtagtt cacattttgg aattttaaca tcatatcttt aaaaattaca
     1741 aaattactat cttttttaac ttttttaact tcttgttcat ataattttaa aacagattct
     1801 cttattaaag ttggtcgctt attttgaata atttcacggt tatctgaaaa cattagtaat
     1861 cctaaatatt tataatggat acttaattgt cttgtcaaac tagctatata ttctaacttt
     1921 tcatacatat taggaaactt gtttcttagt tttttcaaat ctaacttaac ttggtttaat
     1981 tcttccattt catttatcat tttatcacta ctccaattcc catggtttat tgatatcaag
     2041 agactcaatt atatttttag tttgtgatct tttaattttt cgcattttag ctctttcttc
     2101 gccatccata aataataatt tttcttcttt ggactgagga gagattttgg gtactttaat
     2161 tggttttttc ttttcatcca aagctacaaa agtaagaaaa gctacagcag caatttttct
     2221 ttctgcagtg atcatatctt ctgaaatgac tttacaaaat atttccatag acttttctcc
     2281 tgtataaact acataagatt ctatacaaac tgaatcagat tgggtgattg gatataaaaa
     2341 ttctactgaa tctgtagaag ctgtaacaca ttctttaact cttgcatgtc ttctagctga
     2401 tagcgttgcg ttattatcaa tttttttcat taataccccc ccaaataggg tattataatt
     2461 gtttaaatca ttaattaata cttgatccgt actgacaatt ttactgtcac taggaaattt
     2521 ataattttcc ataaaaaact cccgtttcta taatgtttat gttctaatta tagagcgaga
     2581 gtatataaat ataaaatatc ttttttttat acagctataa atttctcaaa tacctttata
     2641 tttaatagtt aattaagaag ttttcttgga gaaatttaat ccaatttttt gttaaagaat
     2701 caactataat atcttttctc caaataatac caagttccca tttcatagaa ggttcattaa
     2761 tatcgatggc ttgtaaatta ttatctaata agcctagtat tccttcgggt aatatacata
     2821 tccctagatt atttaataac atttcttcta tgaagctcca ttgggtggtt tcaaaaatta
     2881 tattaggatt aaagccataa tttctacatg tatttttgat tttatcgttt aaatagaaat
     2941 cagaattgaa taaaataaat tcttgttctt gtaaatcttc aatatcaatc tttgtttttt
     3001 tagataattc atgattttta tgaacgacca gttttaattt ttcttctaaa aaagagaata
     3061 tatcaaagtt tttattattt gtaggaagta cagtaattcc catgtccaaa tcaccataat
     3121 atacatcgtt ttcaattttt ttactaccat tttcaaaaag ttgaaaagtt atattaggat
     3181 acatttcatg aaattccgaa attaagccaa ttaatcttct tatattaata atagtaggga
     3241 ttccaatttt caaatgtccc ttttttaatt ctaataaatt acttaactca ttagggatat
     3301 tatcatacat tttaagcatt tctttacatt ggaaaaagaa agcttctcct gcgtcagtta
     3361 agtatatttg gtttttatac ctattaaata aatttacatc taattcttct tctaataatt
     3421 taattgtatt actaattgtg ggttgtgtga taaaaagatt agatgctgct ttggtcatac
     3481 ttttttgctt tacgacttct acaaaatact gcatatgtct aagttccaat aaatttcctc
     3541 cctttttatt atttcttcac gttaccagtt ttttaaacta attatttttt attattctgt
     3601 ataccgttga acgactaaca tctgtctgtt tagcaatctc ttcgcctgta agtttttgtt
     3661 catcgtataa gaatttgatt tctcttttct tataatctgg caaagaagga cggccgcctt
     3721 ttctccctct tgctctcgca gcttctagac cttttttcgt acgttcactt aataagttag
     3781 cttcaagttc tgcaaatgca ctcatcattg taaaaaacat ttttcccatc gcatctttgg
     3841 ttgacacatt catatcaata atatgtaaat caatgccgtt ttcatctaac cattgagaca
     3901 gatcaattaa ttgttttgtt gtacgtccaa gacgatctaa tttatagata actaggatgt
     3961 ctccttcacg taaatagtct aaacacttat caagttctgt tcttttcgtt ttgcgaccac
     4021 tcactttttc gctaaagata cgttcacaac catagtcttt aagtgtatca atttgtccat
     4081 caagactttg atcttgtgtt gatacacgtg cataaccaat tttagccatt tcaataccac
     4141 ctcttttaat cgttttatgg gaacttatta ataaaatcta tttctcgatg caaataagca
     4201 cgtctctcat cgtctgaaaa ctcatgattt ttgatatttt cgacacattg attatagcac
     4261 aagtttatag acttaaatat ccaagaaaaa cctcttaatt ttaatttaag aggttttgtg
     4321 tcaaaaacga acaataagta acataagttt ctatttaata aaaattatca aataagttaa
     4381 cttagtaagt ttaatagatt tataaattgt ttgggtttgt tatattatta ttttcaataa
     4441 attcaaacca tttcttttta acactttgta ttgaaaattt ttcttcaatt ttttctatac
     4501 ttttttcact catatctttt aaaacttttt cattattttt tagatataat attttttcag
     4561 ctaattcctt tatattgtct ttgttaataa ctaagccatt tttattatta tcaattattt
     4621 cttctggacc atatttaaaa tcgtaagaaa ttacaggagt tccagatgcc atactttcca
     4681 aaatacttaa tgaaaaacct tcacttttag aagtggttat agaaaacaat gattcattat
     4741 atatttctaa tggattatta gtataccctt taaatataat attattttct agtttatttt
     4801 ttttgactaa ggattttaaa ttttctaatt catttccatt tccataaatt tccaatataa
     4861 aatcaggatc atcatcttta attagttgca ttgctttaat tatatgatca atttgtttta
     4921 atttaactaa tctagaaata acaacagctt tgttttttct aatgatgtta ttaatatctt
     4981 ttgaaggcaa agtctgtata ccatgtggaa taacttttac tttttctgaa taaccataat
     5041 tatttacaat atcctctttt tgttggcttg ttaatactat taaagaatct atatttttaa
     5101 gattttctaa agaagtcatt acagttttag ctatctcgcc atttgggctt aaatgattac
     5161 tatgcaatct tacattctta ctagaatttt cattttttat attaatcata atatcatcag
     5221 tatttcttgc atcagaaata ataacagaat ctttattatt attgacaatt tgttctacaa
     5281 aataagactt taattgtcta tcacttctaa aagaatgaac tatttgccct ttttttatta
     5341 aatcaacttt agtagctaat ccattttcag ggtttactgt tttacgtaag taacagttac
     5401 caatactatt gtaaaaagtc atttgtctgg gtctatttaa attataatcc atatatgata
     5461 gtttacctat atatccttca ggagcataaa attctacttt aattcgataa tttgaattat
     5521 taaagtaatc tattttttta atagattcat cacttctgta agatatattt tttttatata
     5581 atccattttc atatatttta acaatgtctt tactgtcatt tttttcaact attgaatcat
     5641 catttattag atttttatat gacttgaatt tttggtcaat ctgatcctca tttctaaaat
     5701 aatcatacat atttattatt ttaacttttt tgtttacctt atatacatca taaatatctt
     5761 ctataatacc gttataatcg gaattataat taaatgtcag tatataagtt tcgtaaccta
     5821 attcactaaa catgctagct tgttgtaaat tagccttagt aagacctcct cgttctagtt
     5881 ctaaagaatt aattaataag tatatttttt tcaaattcac acctcttttg ttttgttcat
     5941 attaaagtat caatgcttat ttatatctaa tttcttttat agccccccag aaaattagat
     6001 tgtagactgg agtattatag tatattctat ttatatactt attatactat aatttaagga
     6061 aggagaacta ttttgctaca tataaaacaa gaaggcactg tgctttatat ttcttttggc
     6121 gaaccaaaag aaaacattac aggcctatat gtaaaaaata gctttaaatc tattttttac
     6181 aaatcatatg atgagtcgtt taattttaaa attgatttaa atgaagtatt agacatcttt
     6241 aaagaattta atgaaactaa gattttctta actttgggag tattagaaaa caagcgtaaa
     6301 aaacaaaaaa atatagaagt tactaacgaa tatacatcta tttataattt agagaaagtt
     6361 tcagatggtg ttaacacaat ttatccatat atcactaaaa acggattttt acattttaca
     6421 atgactaatt acactccatt aaaagcattt ttttcaagac gacatatcga taaactaaaa
     6481 ttcaataatc accaggcgct aatagaaggg caattttcta ttattaactc cacaattcaa
     6541 aaagctagtc ttgttttgac aacgcgcttt actgatcggg aattagaagt ctatttacca
     6601 agtactgtag atagtaaaaa taaaaatact tctacattta atttctccgt tgatatatac
     6661 aacgagttaa taaaattcat gaagcattca tttatcattg gagatgttat tgatatctat
     6721 ttaaaaattg atattcaaga atcatttgta cctttaaaaa taaaaatagg taatccaaga
     6781 gttttaatag aacgctttct aaagggcgaa attattacgg attatcaaaa tgatattata
     6841 tctattactc cttactttac tatgaaaggg cgtaatcttt catttagaat taacagatat
     6901 acaatagata gttacctaac ttatattgaa aattttaaaa aaactaacgt gaaattaccc
     6961 ttccaaaaaa atcgtccaaa agtttgggtt gtgggggaaa aatcttataa agctcaagat
     7021 aatggttttc acttttttaa atatatgcgg acgcaccacc cagaattacc tgtttattat
     7081 attattgaag aagattctaa tgaaatccaa aatgttcttc cttttggtaa tgtcatttat
     7141 tacaaatccc cagaacattt caagattatg ttacaagcgg attatatatg cacaacacac
     7201 catccagaat taatattccc taccaatagt gtaatttata caaaaaaaat caaagctact
     7261 agagtgtttt tacaacacgg tgtgttaggc actaaaaatt tatcaaatat caatggtaac
     7321 caactgaaag atttcaatgt agaccttttt attacaagct ctgagagaga aaaacagatt
     7381 gttgttagag atctaaaatt tgatagtagt caagttgctg taacaggttt agctcgtttt
     7441 gacaatcttt ttaatccaaa agttacaact aaaaaccaag ttttaatcat tccaacatgg
     7501 agagattggt taatcaatat agaacagata gaatattctg aatatcttaa aagaataaat
     7561 caattattaa atagctctaa tattaaaaat attgtaaatg acggaaatga agttattttc
     7621 tgcctacatc ctaatatgca acctttcatt gattcgttta atgtaccatc gtatattaca
     7681 agtattaaac aaggagatgt cgatgttcaa aaactaatcc aagagagtaa attaatgata
     7741 acagattatt caagtgttgc ttttgatttt agctttttaa ataaacctgt catttattat
     7801 caatttgata aagataaatt tttaggtaag caaccttcac atatagatat agaaaatgaa
     7861 ttgcccggta cgatagttaa taatcaacaa gatttagaaa aacaactaaa aaaaatgatt
     7921 atgaataatt atcaaatcga taaaaatgtt gaaatgaaag caaatcagtt tattaaatac
     7981 catgatcaat acaacagtca aaggattttt gaagctgttc aaaaatccaa aacaactaat
     8041 cgattaaaaa gaaaattcaa atatgatatt ttaactcaac atttattcaa acgctttagg
     8101 aagagtaaga aatattttaa cgttatggat aaatataact cagctatttc caaggtagtt
     8161 ccagttaaaa aggacctggt tgtgtttgaa agtaacgtag gtaaatctgt gagcgatagc
     8221 ccaaaagtaa tttacgataa attaaaagaa tacagtgacg cttaccaaat tgtatgggta
     8281 agcaacccac aatttccatt taatgatcct aatgttataa gagtaaaacg tttatcaccg
     8341 gaatactatc attatttatc ccgtgcaaaa tattgggtaa ataaccagaa ttttccgcat
     8401 tatattacaa aacctaaaga tacaatatat atccagacat ggcatggcac gccacttaag
     8461 aaaatgttaa atgatgttga aagttttgaa ggtagagacg ctaactataa aaaccgtgtt
     8521 aacaatgcaa ttaaacattg ggattatctg gtttcaccaa gtccatacgc atctaggtgt
     8581 ttcaggtcag cctttgaatt tcaaaaagaa atattagaag ttggctatcc acgaaatgat
     8641 atattttata atgaggatat agtatatatt aataataaaa aagaaaaaat caaacaacgt
     8701 ttaggtattc aagatgaacg taaaatcata ctatatgcac caactttccg tgatgatgaa
     8761 gttaataaag ctaaaaaaca tatcattaac ttacaaattg atttgcaaca aatgaaagaa
     8821 aaactaagta aagattatat tttaattcta agaccacaca ttattattag taactcttta
     8881 cagttagata gttctttaga taattttgtg attaacggca ataaatataa tgatatcagc
     8941 gatttattct taataactga tatttgtatc actgattatt cttccgtaat gtttgatttt
     9001 gctaatacaa aaaaacctat gctattcttt acttatgatt tagaacacta tagagatagt
     9061 ttacgcggat tttattttga ttttgaaaat gaggcccctg gacctcttat aaaaacaaat
     9121 gactctttaa taaaatctat tgaaaatatt gaacaaattc agcaacaata tcaaatgaag
     9181 tatgaaaaat tttatgataa gttttgttca tatgaaaagg gaacagctgc tcaaagtatt
     9241 attcacaatt tttttaaata atatataact attccattaa aagaattaat aatacttttt
     9301 tcatttcaaa gcgtttcaca aaactactat tcatacacta aagctaatat aaaaacatac
     9361 aaaactcatc ataaccatac gttaaacaat tagttaacat attcgatgat tatcagaagt
     9421 tacaaaaaat gcgtcactag tatagtgacg cattttagca ttttctttat ttgaaaaatt
     9481 actataaatt aactttttaa tacttattat tttctaaaaa ttcttctaaa actttatcaa
     9541 ttattgattt tatagacgta tctttatcta acgccatttg gtttagcctt ttcttaatat
     9601 cagtatctac tctcattgtt gtacttttag atataggtct ataattctct gtgtatttca
     9661 cttccgaagt atctatatta tctaaaaatc cagccataca tttcattcct cctcaattaa
     9721 tttaattcta ctaactaatt cttcatatac tttgttgaac atatgtatga cttttttatc
     9781 atgcatatct ttatctttta tcccatcagc agcgaacttt tttattcttt ctctttgata
     9841 tatttggtgt tcaaataatg cttcagaaaa cgcagattta gacatctcta atatttgttt
     9901 atctactcgt ccattttttt ttattaatac tggaactgca ccaactaatt caaatggtaa
     9961 atctgactct ttttttctat ctcttagaaa attaacaaaa gaaagactgc tctcataagc
    10021 tgattgttgt gtttgaaata ccattaaaat ataattactt gcgtaaacag cattattagt
    10081 aaaatctgaa tttatagtag gtggcacatc tataaataca taatcgaaat cataaatttt
    10141 ttcaattttt tctaccacat tttttaaaat atatcttttt ttcaaaatgt ctgtttttga
    10201 aataatatcg gataaattag ccaaagacga atcagcgggc aataatgata aattagaagt
    10261 taatctaatg atactttcat ctatatttcc actttttagc atatttatga atgaaagtga
    10321 ttcctcttta aattctggat aagttctttt cataatttga gtagcgttac cttgaggatc
    10381 aaaatctatt aaaagaacct ttttgttata gttttcagat gcaatataag aaagtaatgt
    10441 agatactgta gttttaccta cgccaccttt aaaatttcca actgttatta tattcaaaat
    10501 aaccctccta cataatctca ttgttcttaa ttcattctta tatattcttt gtgttgtttg
    10561 ttacatgtaa catgttactg caaaactttg tttctttcaa cttatacata atctcattgt
    10621 tcttaattca ttcttatata ttctttgtgt tgtttgttac atgtaacatg ttactgcaaa
    10681 actttgtttt tttcaactta tacataatct cattgttctt aattcattct tatatattct
    10741 ttgtgttgtt tgttacatgt aacatgttac tgcaaaactt gtttctttca acttatacat
    10801 aatctcattg ttcttaattc attcttatat attctttgtg ttgtttgtta catgtaacat
    10861 gttactcata aaaagttaca aaataaattg tttctatagg tatataagtg ttattattaa
    10921 tttataacaa aataaaaaga gcaactattg gtagtagttg cccttaaatg tttggtaata
    10981 aaacgttggc acacgtttat ttaatatcaa atttatactt gtattatata atgaatgatt
    11041 acttagtgca agtattgaag ttattatatg aacggaaaat atataaaagc gttttattac
    11101 ctcttaccaa tttaaaattc ggaaagaggt tttttattat gacaaatgaa gaaaatcaaa
    11161 aattcacaaa actacacaaa ttcttattta cagacaacaa gttcaaagct atgagagcca
    11221 aaagtaaatt actctatgcg attattactg aacgtcaaag tttaacaatt gcttatgcaa
    11281 aaaataacca agatcaatct caatttttag atgaaaataa acgattattt tcaatatatt
    11341 caaattcaga tttaaaaggt atgctacatg tttctgaacc tacaattata aatttaaaaa
    11401 aagaattgat tgaatatggt cttttagaag aaataagagt tcctacttca aataatcgat
    11461 tatatcccaa aaagccatat gataaatact attatctaaa tgatattgat gagttttatc
    11521 gtttgcctta tgcacttttt gataatccat tttataataa actatcgccc gatgctatta
    11581 ttacttacgc tatttatcta agtcgttatg aatatagtgt atttaaagat attttttacg
    11641 ataaaacaca taatatttac tgcgtgatgc caaatcaaga aattgcaaaa tttttgaata
    11701 taaatcgtaa aaaagtggct aggctcaaaa atgagttaat tgcttatgga ttaatagaag
    11761 taaaaccttc aaaaagagca gataaattat atgtaaatcc tccaaaacag cgtaatgaca
    11821 acaaacttaa aaaatgggac attgcaaact taaaaaatgg gacattgcaa actaaagata
    11881 tgggacattg caaacttaaa aaatgggacg ctagttatac tgattttagt aacactaata
    11941 ttagtgttat tgattctaat gatatgaatg atatgaatga tataagagag gcaaatatag
    12001 aagatacaaa acctaatcaa ccaaatcata cagatcattt acaaaagcaa tccgatgaag
    12061 aagctttaaa acatttagaa cttcaggaaa tgcccgaaga tacaaaaaga tacatgaata
    12121 attttagtgc taaagaaata caaatcatta aatcagttat actaaaagct aagcgttcgt
    12181 ttaatgattt gtatggtgaa gtgtatatgc ttgaagatat ggatgatgaa ttatttacgg
    12241 tacttaaaag attcaaaggt ataatggtta aaaaacaaga aaaattggaa aatatgcaag
    12301 gatatttaat gcgctctatt ttgtccgaat tagaagaaat gcgctcaacg aatatgcgta
    12361 gaaaaaactt tgaaaacagc ccactcaacg tatttaaatc ataaaataca agaaaaaagg
    12421 ggaatgatag gctatgaatt tttcgttagt gaaaagctag agaactgcaa atataagtat
    12481 atcaaagcga ttaacgatta tataaaacaa gaaaaatctc atattatcgg tatcgattta
    12541 ggcaaatacc attacttaac agcgtcaaat atagaccgat cttttgtttt tgtcgataaa
    12601 cataacacgc tcttccatct ttttagaaaa tacgagagac gtattgctaa taagcaatat
    12661 gataatagcg aagcttattc taaactgaaa acaggactta aaagccatat caatcaagtt
    12721 gttaacgaaa tgttagaaca aacgtccaat cgttttcaaa ccgtctttgc attagatgat
    12781 catggttcaa gtcatttatc ttttcctagt ttggtatttg acttaactta ttttgcgatt
    12841 aagcagcgaa aaaatgaaag tgacgaaata ctgatcgttg atgaaagttt cacgtctatt
    12901 gaatgtccaa tatgccatga tagaaatcag tacaacagaa ctaataaaaa taagtttaag
    12961 tgtacaaaat gtggattcat acatcaaaac aatgatattg tagctgctag caatatagca
    13021 aagaaaggac aattattaaa ttcttaatat aaagggggga taaaatgatg aataataaac
    13081 aaaaagcgag gctaaaacat tacaaaaact atgattatcc aaaacaagcg tatgctttct
    13141 ttgatcataa aaaggtaaaa gttgttttaa ataatggaga atcatttacg gggtatattg
    13201 ttaaagaata tacgtacgaa atattattag tgaaaagcga tggcatcaaa gatccaaaag
    13261 ataatgaatt agagaaacgt acgctcattc ctaaacactc gattgcttat acgaccaatt
    13321 tcattcattt acctcaagaa taaagaataa ttaaaattag ttatattggt tttgagggga
    13381 tttttagcgt gaatataggt cagaatcttt agttcgacct ttaatattca tgctgtagca
    13441 aacgaacaaa gtgagtgcgg tagaatcata cataacgtag caaaataaaa aataattatg
    13501 ataatcaata atgtttctct gcactatcat gtgctagagt gaaattagag aattaatagt
    13561 ccaatcaaaa catattctct tgtcattttg tataatattg cttccaaagc cctaactact
    13621 atttgtagtt agggctttta atttctggat ataaaaataa ccccacacct tattaggtgt
    13681 agtgatttaa aaggtaatat acacaagaaa atataaataa aataagagat gataagcgaa
    13741 agcactctat ttagtgtttt tcctaaataa atgttgataa aaattttgat aactaatgtg
    13801 tcttgttaaa ggtttttatt aatatatgtt tcacgtagaa cagtattggt tttaagtgat
    13861 tagtcgtcgc gattttcatc actttttttt atgtttagga gccaatatat ctctaataat
    13921 ataaataatt gtcattaaaa ctataaaacc aatagaccat ttaacatctg gaaaatcagt
    13981 gaaaattagg ttctgttgca aagttgaatt tatagtataa ttttaacaaa aaggagtctt
    14041 ctgtatgaac tatttcagat ataaacaatt taacaaggat gttatcactg tagccgttgg
    14101 ctactatcta agatatgcat tgagttatcg tgatatatct gaaatattaa gggaacgtgg
    14161 tgtaaacgtt catcattcaa cggtctaccg ttgggttcaa gaatatgccc caattttgta
    14221 tcaaatttgg aagaaaaagc ataaaaaagc ttattacaaa tggcgtattg atgagacgta
    14281 catcaaaata aaaggaaaat ggagctattt atatcgtgcc attgatgcag agggacatac
    14341 attagatatt tggttgcgta agcaacgaga taatcattca gcatatgcgt ttatcaaacg
    14401 tctcattaaa caatttggta aacctcaaaa ggtaattaca gatcaggcac cttcaacgaa
    14461 ggtagcaatg gctaaagtaa ttaaagcttt taaacttaaa cctgactgtc attgtacatc
    14521 gaaatatctg aataacctca ttgagcaaga tcaccgtcat attaaagtaa gaaatacaag
    14581 gtatcaaagt atcaatacag caaagaatac tttaaaaggt attgaatgta tttacgctct
    14641 atataaaaag aaccgcaggt ctcttcagat ctacggattt tcgccatgcc aagaaattag
    14701 catcatgcta gcaagttaag cgaacactga catgataaat tagtggttag ctatattttt
    14761 ttactttgca acagaaccaa aattataata cttctgaaag tcattcagag cctaatacag
    14821 aacaagaaag caatacagat aaaaatagcc acaacgataa aaaagggcta tttagcagac
    14881 tatttggacg ataatattat taaaaaacca cctaactgat ttaaacagta aagtggtttt
    14941 ttcatctata atgataccta catgaagcaa ccatgattga agtatcattc accgtatata
    15001 ctaatctatg ttcctgatta atccgacgac tataatatcc cgaaagacta ccaaccaatt
    15061 tttcaggttt cccaatacct cctaaagccc catctctgtt aatactttta agcaatttat
    15121 tgatacgctt taccataggt ctatctttta actgaaagta ttcataatct tcaaatgctt
    15181 gaggtgaaaa agtaatattt aatttagcca tttatatttc tatttcctta cttttaacat
    15241 taccacgttc taaattctca attgattctg ctaaatgttt tgcgttggaa ggattttgtt
    15301 gaagatataa tgtttccata attgcgtcgt aatcatcttc tgacatcaac acagcgttac
    15361 ggtcttttgt tgtaatcgta attgtatcgc tatcatcatt taccttatta atcatatctc
    15421 taaaattatc tcttacgaac gtataatttt taaccgtcac aataaaaacc tcctttatat
    15481 ttctatgatt attgtacaat tttctgtacg taaattcaat tgattttgct caccttcact
    15541 taacaatcac gtctaatatt atgttaaaat accaacataa taacaagggg aggatataca
    15601 atgaatgata aaattatggg cgacctttta gacgagttaa ggattcaaaa cgctttaaaa
    15661 gagctagaaa cagacttaca agcaagccaa atacttcata acgcaaaaca ctgctaaaca
    15721 atagcacatc aatctattgt ttagtcagtg tttaaattat tttatattca actcaaactc
    15781 tttccaattt ctctataaat cttctcagct tccccttcgt tttcaactcc atagacatgc
    15841 attcttccgt ctttgaacag tgtaatttca taaggcttat aggacagtag tttcacaaaa
    15901 ttattagctt tttttaccgt aacaggtaaa taatcagtat ggctaaaaat atcggcatta
    15961 aagcgtaata agaacatgtc tccgcattgt ttctctatct tgttgtcgta tttatcgttt
    16021 aacaatgcat actcatgttt cttacaaaca ttacaatcac tttgttttaa ggcattaaca
    16081 tccatcgact tatattgcat attaaaacaa tctatagtta taagtttctt tgaaaatgct
    16141 tcgccagaga cccatctcat tagctcggaa acttgtatac tagctacttg ataaatcact
    16201 ggtggcagca caccatttat tgcacaactt tcaccagtac ttggcattgt ttcaagtaga
    16261 catttcaaac atggcccttg atcatcgata ccataaacag tacctttact accaactgca
    16321 gcaccgtaaa tccaaggtat attttgcttg ttacaagatt cattaattaa atatcttatt
    16381 ttaaaatgat ccataccatc tataacaata tccggatgat atgtcgataa tagattttca
    16441 atatttaaat ttgttatttc acgatcaatt gctattactt gtacgttact atttatttga
    16501 ttcaacttat gctttaatgc ttcaacttta ggtaacatct tttctgcatc caactcatca
    16561 tataacgctt gtctatgtaa attggataat tcaacaatat ccatatctat tacagtaagt
    16621 gagcctaccc ccatccttac taacatttct gcgctgtgac taccaagtgc acctgcaccc
    16681 ataatcatga cgtgagtttt ttgaagttgg ctttgaccgt actcaccaaa ctgatgatat
    16741 cttacttgtc gattgtagcg ctctatcata agaacccaat tccttcagtt ggactcgatg
    16801 cttgtgctgt atacttcaca ggtattcttc ctgcttcata actcaatctt ccggcactaa
    16861 tccctttatt cattgcttct gccattttca caggatccgc tgcacttgat attgccgtat
    16921 taagtaaaat accatcagca cctaattcca ttgcatgaca agcatcctta ggtgagccaa
    16981 tacctgcatc tacgattact ggtacattga cacgttcaat aatatagcgc aaatttaatg
    17041 gattattgat tcctctccct gtaccaatag gagaggcaag tggcataatt gcatgaacgc
    17101 ctaactcttc taagcgtttc gctaagacaa catcattaga tatatatgga cagaccgtgt
    17161 aacctttttc cagtaacact ttgcatgctt catatgtttc taatgggtct ggcagtaatg
    17221 tttcgtcatc accaatgact tctaccttaa tcatgtcaca aacacctgca tgattagcaa
    17281 tttctgctat acgaactgct tctttagctg tcttagctcc agctgtattt ggaaatgtga
    17341 tgaatttcga taaatcaact tttgctaatg gatttggtaa atctttgtca tataaattca
    17401 tgcgtctcac tgcaaaagtt aatacttctg tttctgctgc tgcaatagcc tgagtttgta
    17461 tctcttcatt atcaaatttt cctgtaccta ataataatct tgaatttaat gtaaagttgc
    17521 ctattttaaa catattaacc gcctcctaca aattctaata attctaagtt atcttcatca
    17581 ttgactatgc gagatgtaaa ttgttctcgc ttaattaatg tttcattatg ctctacaata
    17641 atacgtgttt catccagtcc caatgattga attatttctt gtatattaat tggttgttca
    17701 aagttaaata cgtcaccatt aatcttacat ttcatttcgt tcacctctcc taatctgaaa
    17761 atcatacaat tgtttcggcc tatgcccact gataatccat tgactcatca actcacctat
    17821 taaaggcgaa agtaaaattc cattgcgata atggccagca atgacaaata agtctttatc
    17881 cacttcatcc ataataggct gttcgttttg acaataaggc cgtatacctg accattggtt
    17941 tatgattttt ccatttttca aatctggtat atagtgcaaa gcttgtgatt taagccatga
    18001 tttaccagaa ttagacaccc caactgaata atcattaaag taacttgttg caccgattaa
    18061 atatctattt tttaattttg gaatgacgta acaaccatta gtcagaaaca tggtaatatt
    18121 caagtttaaa tcaggttgtt ctaccaatag cgcttctcct tttaccccaa taaccgtttc
    18181 acaaggtaaa tattgctgta aaagttttcc tgtccaagcg cctcctgtga caattaactt
    18241 ttcagtataa taagctccat ttcgtgtctc cacacggtac ccatctttta tggattcaat
    18301 atgggttaca gttgtttggt atattctatc tatatgtcta tttgataatg acttcaacaa
    18361 ccctttagta tagcggtttg cattgatttg attatcttca ggcatataaa taccatttgt
    18421 atgttttgaa gttatagcac cgttggacat gtgttgaaca tcagtaggac taagacgttc
    18481 tacagatgca aaatgttgtc ttaaaaattg atattgctgt tcaatctttt tattatcata
    18541 atggttcgta gccaatttta ttaatccact atttaaatac tcaatatcca cgccaacctc
    18601 ttccaacaaa ctatctctta gaggtttgaa catcttttga gaagttgttg ccaaactaaa
    18661 caaagcacta tttttggtga attcattttg cgcgcctaac atcccacctg ctttataaga
    18721 tgcatgctta cctgcttcat ctctatctat cacagctata ttcgcaaaag actgacttaa
    18781 cccacgtgcg attgacatgc ccatgactcc cgatccaata ataatgacat catacatgtc
    18841 catcccacac ttccttcatg tttataagtt tttctttcga atattgatta aaaacagaaa
    18901 taccggctat tcctgaaaat ccattaggta aagaagataa agtatgttga ttaatacctc
    18961 caattgcaat aatcggaata tcaatttgta gcgcttcttc aacctccgac tttgctctag
    19021 gtgtttgttg aggtttagat gacgtctcga atacgtgtcc aaataataca aaatctagcc
    19081 ctaaatattt agcgttagca atagcatctt tatggtgcgt agacatactt atttgcatat
    19141 cgggataact agcttgtacc tcctcaatat aaggatcact ttccctaaaa tgaattgccg
    19201 acaagtcaca ttgtatgatt acattgatat cactatgaac aataatctta tccttaggaa
    19261 actcattttt tagtaatccg tgaacccact gaatgacttc ttcagtattc attggcactc
    19321 ttattaataa gtaatcgata acgccttcga tttcacagta atgcttaata tgtgatttag
    19381 acaaatcttg atatggtgta atagcaataa acaatatttt caccccaaat aaaaaaacgt
    19441 tacttttcct ggtggaaaaa taacgttgta tgattacatt tatcatagaa aacgccactt
    19501 tcctacgcca gtgcgaactg gatcaggttc taggaatccc tcagttatta cttcggtctc
    19561 agcctttatc aaaggcactt ccagtggttt ctatctatta aattttcgtt tcataatgtt
    19621 ttagtgatta cttacaatct aacttataat catttacttt tcaagtctca cttcaacttt
    19681 gacaacatgt atcctaaagt cagctggctt aatcgtgcat aatcacgctt atagagacaa
    19741 ctctaacaac cgtgctgtta tcggtcgtgt ctgacgatag acttcttgat atatttcaaa
    19801 gtatttaaca tagcgttcat gatgcacttc attcggcaga aaagttctat catagacgat
    19861 aaattgatca actacatctt ctaggctttc ataccaactc aaaccgacaa tagctagcat
    19921 tgccgccccc atacaaggcc cttcttcata tttcaattta ctgacttttg cattaaatat
    19981 atctgcttgc aattgtaacc aaaaatcatt tcttgcaccg ccaccgattg atgtaatgtg
    20041 cgttatgtcc ttcccttgtt cacgtaaatg taccaaagtt tcatataatg aataagtaat
    20101 accttcaatt actgatctcg ctatgtctgc atttgtatgt aaagtgctta gcccgataaa
    20161 gctacctcta atttgcgaat caccatgtgg tgtacgttca cctgataggt atggggcaaa
    20221 taacaaccct tcactaccaa ttgtagagtt acttgctaag cttaaaattt ggttaaaagt
    20281 taaaccggga aacacatgtt tttttaacca attcaaacta tctccagcag caagcgttac
    20341 gcccattaca tatgatttat cttctacaac atgattgaaa tagtgcaaat tatgacgata
    20401 cgtctttcct tcacctgatt cacaagttaa taacgtacca gaagtaccaa tactgcataa
    20461 tgtatcgttg gatttgataa cacctgcacc aagtgcacca catgcattat cgccaccacc
    20521 agcaaaaaca gctacctccc ctgttaatcc taatgattta gctaggctgc tttctacata
    20581 tccaataaaa tctccagatg atacaagtga gggataaatg tcgtgaatgc gaaattgtga
    20641 gccggttgtc tttgaccaac ttttttgttt tgggtccaat aataatgtgc tcgaagcatc
    20701 tgaatattcc atatttattt taccagttag cttaaacctc acgtaatctt taggtaatag
    20761 gaacgttgct atcttgttcc aattattagg ttcattatct tttatccaaa gcaatttcgt
    20821 taatgtaaaa ccttctaata ctgggtttga taatatataa tcgccaaatt gttgttcgat
    20881 tgttgtgcat tgatgggttg aacgagtatc attccataaa attgcatttc gaaggggttt
    20941 attagtacta tctaatacca ctaaactatg catttgacca gataacgata agcctctaat
    21001 ataaatgtcg cttaacgcgc tagcacttaa tatttgtcta atacatgact tggttgcctc
    21061 aaaccattcg tctggttgtt gctcattgca cccagattga agttgtatta tatcaagtcc
    21121 ttcactaact ttagctagaa cttctccttc tttacttacg gctataactt taactgaact
    21181 tgtacctata tctatgccta acactgcttc attcaatatc atcgattcct ttcttttgct
    21241 ttctctaata aattcgttct cgttaaacca taaggggaac tcattacaga aaatatataa
    21301 ccttcagaaa tacgtgctaa aatagcggtt ctgttgcaaa gttgaattta tagtataatt
    21361 ttaacaaaaa ggagtcttct gtatgaacta tttcagatat aaacaattta acaaggatgt
    21421 tatcactgta gccgttggct actatctaag atatgcattg agttatcgtg atatatctga
    21481 aatattaagt gaacgtggtg taaacgttca tcattcaacg gtctaccgtt gggttcaaga
    21541 atatgcccca attttgtatc aaatttggaa gaaaaagcat aaaaaagctt attacaaatg
    21601 gcgtattgat gagacgtaca tcaaaataaa aggaaaatgg agctatttat atcgtgccat
    21661 tgatgcagag ggacatacat tagatatttg gttgcgtaag caacgagata atcattcagc
    21721 atatgcgttt atcaaacgtc tcattaaaca atttggtaaa cctcaaaagg taattacaga
    21781 tcaggcacct tcaacgaagg tagcaatggc taaagtaatt aaagctttta aacttaaacc
    21841 tggctgtcat tgtacatcga aatacctgaa taacctcatt gagcaagatc accgtcatat
    21901 taaagtaaga aagacaaggt atcaaagtat caatacagca aagaatactt taaaaggtat
    21961 tgaatgtatt tacgctctat ataaaaagaa ccgcaggtct cttcagattt acggattttc
    22021 gccatgccac gaaattagca tcatgctagc aagttaagcg aacactgaca tgataaatta
    22081 gtggttagct atatttttta ctttgcaaca gaacctttta aaacctaagt actacataca
    22141 ctagaaaaaa ggaagtttaa acataaaatg ttttctagtt ttttcacaaa ttacatgtgc
    22201 atttttatct gtttagttta atcttattta atattaattg taactgatta tgcatttgta
    22261 tgggcatcta caatatcacg acattgttta gcagcttcta cagggtcatc agcatttgca
    22321 atgccgccac caacaataat taaatcagga ttttctgcaa caatatcttt aattgtatct
    22381 ggtttaatac cacctgcgac tgctacttta gaattactaa ttacagattt aactttacgt
    22441 aaactttcta aaggagattg accttcagct tgtaagtcat aaccagtatg aacagcgata
    22501 taatctgcgt ctaaatcatc taaatcttgt actgcaatca tagctactaa ttttagaaaa
    22561 gtaatcgttt aagattaagt gaattacaaa atacactacc ttatatcaat cagcgtatgt
    22621 taataagaaa acttcgagaa ttagagcaag acaaaatcat tgaaagaact gtctaaccag
    22681 tagttccccc taaagtaggt tgtaaattga atgaaataga attaaacctt gataaactag
    22741 tttcttcaat ttgtagttag agcattgact ttctagatac aattaaaagt aataatcata
    22801 ggtattaaca taagtaatcg ttattagaaa ttattatgcc tttttattaa atttagttac
    22861 taaacaagcg acttcaaata ttaagtgaaa tcattctcat ataccaagta aagtgacaaa
    22921 taaacattga aatttcattt ttcaactatc taaattaatt tactctagta gtactttttt
    22981 aaaaatgtct tttcaaaatt catgagctga tacataaatt tttcaaaatc ttctctaaca
    23041 aaacaactta acaaaagtaa ctttatttct tttgttaagt ttattttcat ttcttttaat
    23101 aagcgttctc cattatgcgt caaactcaat aatttagtac gtttatcatt cgaataaact
    23161 cgttgcacat aacctttgct ttctaacttc ttaacacgtt ttgatgcagc tgtcttataa
    23221 gtacgttgct tatttgctaa gtcgttaatc gatacttttt cattatgctg aataaaatac
    23281 attgtttcta tttgttcata agataagtaa cgacctggtt ccaattcttt aaccatgtta
    23341 gtaattgctt tattaatatt cgctgtagca tcatagaatt ggttaattat tatttctaag
    23401 tttccctctt tatgctccat attaaccttc cttactaaac tatcgttttt caaccatcat
    23461 tgatttttta aaaattaaat attacttatt ataagcataa taactttatt ccattacatc
    23521 actttcttca gctttttcag ttgcttttct catcagtgga tcagtaattg gtttaaagat
    23581 aacaccaatt aataaaaatc ctataccaaa taatgaaagt atcactaatt ttttagttaa
    23641 aatttcaggt acaggtcctc caactgcttc tcttaaagca tctattgaat aagagaaagg
    23701 taaataaggg tgaatgactt ggaagaactc tggtgtaact tggataggga aggttcctcc
    23761 accacctgct atttgtagta caaggaagat gattgcaatt gctttccctg gatttcctaa
    23821 caatgacact aaagtataca caattgaaat aaatacaagt gatgagaata ctgatatagc
    23881 aataaaccat acaacagatt caacttgcgc tttcagtatc accatatctc caattgatac
    23941 gatgagtgct tggataatac ccaacgtgta aaacaaccca ctctttccta gataaatttc
    24001 tcttgtcgtt agatgtggct ctaatgattt atgtttatta tctgtcgtta ataaacttac
    24061 tagtaataaa gctcctaccc atattgctaa tgctgtgtaa aatggtgtgc ttgctgaacc
    24121 gtagtctttc acaggaaata tgtctttttg atctatatta attggatttg cgattacatt
    24181 agcttgtttt ttcaaatcat ttttcaataa gtctaccatt ttatccactg catcgtcgtc
    24241 ttcaatctcg tcaaatagtt tgttcgcttt agccagatct ttttcaacat ctggtaattg
    24301 attacgtgca aaatctgcca aattgtgcaa gctttctttt gcacgtggtt gatttgtatc
    24361 taaaatatct accaaattat catagcgatt aaacagtgta ggtattgtat tgttcacagt
    24421 tgctgttgta tcagataact gttgttctaa acctggcaag tcattttcaa taaatgatgc
    24481 tgcgttagaa acactttgtt taaattgtgg ataataattt tgagcaatag acattgcatc
    24541 catatatctt tgctcaatga ctggtagtgc actttgaatc gtctcaactc tatccttacc
    24601 agtagttaaa atactttctc ctgaatttat aacttgatca attgtgttta atttcgattg
    24661 aacagttgat agttttatat cgccgtcatc taataatgac atcacatcat tagatacatc
    24721 taataatttt tggtttagtt ctgacttaat atagtttctt aaatcatcta agctactatt
    24781 cacgcgtgga atttctttaa gtaattctac tgcttcttct ttaccagaac ttccattcga
    24841 aagtgcttca ctaagttgat tttgtgtctt aattaaatta ttaattctat tatttgctga
    24901 ctctaattcc ttaatctcat cagaaagatc taccttttct ctatcttcaa gctctgataa
    24961 tatatctata aacttttgat tggacttact tgttacttca agcctagatt taatattatc
    25021 taaagtttct ttgaaatctt ttggcttatc tgtagatata ataccgtaag tgacattttt
    25081 tagcgcatta atatcttctt gactactttc cgcttgtttg tcggtataat tggataaaga
    25141 taataatgat tttgatagtg aagattccat tgcgcttaca tcttcactac ttattgctgt
    25201 tccattttga ttatttccag cattgtcgct attactatta cttatttgcg aagttttaat
    25261 atttgaataa ctatctgacc ctttagaact ttgctgctca gtttcaacat tttcttgtaa
    25321 tcgattatta gcattttgat ttgcttcttg tgcattatca acgacttctt gatagccttc
    25381 gacacgctgt tgcactgcag gtaaatatcc ttgcgcttca ttcaggcctt gtaaccctgc
    25441 gtcaacccct gcgcttgcaa ggtctacacc acgattaatt tttggaaaag cttctggtac
    25501 atcattagat gcaacattca aggcattctc aatatttggc atgtagtcat ttaatgccaa
    25561 tatcaattta gctcgctcat ttaatgtcgg aatggccgca ttaacttggt ttaatttatc
    25621 tgcagcatct ataacctcac ctttatgatt tcctaacgct ctaaattcat cagcataatt
    25681 gtcaatttca tcctgatttt catctaaata tattatttta tcagcaaaat cattaatttt
    25741 gggtatagaa tcattagctt tagatactgc atcttcaatt ttatttatgg ttggaatttc
    25801 ttcctcaagt ttcacgccaa gtcgatttgc ttcatctaat aatgcttttg ttactgtctc
    25861 attaaattgt tcatttgctt tttgaacaat ggcactcgtc cctgcatttg tcattttagg
    25921 cgcaatcgca ttaagttttt gattcacttt gtattctacg tctgcttgct gtgggttttt
    25981 tcgaagtgtg ccggtaattt ggtgtgtaaa cttctctggt atgtaaatgg ccgcgtaata
    26041 atcgcccatc ttcaaatcat gatcggcttt ttttcgactt acaaattgcc aatcaaagtt
    26101 atcatctttc tttagtttat tggtgatttt attgcccacg ttcacatttt tatctttaac
    26161 tgtatctccc ttatcctcat ttacaacagc cactttaata tttttagtat taccgtatgg
    26221 atcccatgtc gcttctaagt taaaccaagc ataaaaagaa ggaagaagtg ctaaacctcc
    26281 taaaatcact aaaacagcag gcgtcttagc aatctttttc aaatccatta caaataattt
    26341 tattgcgttc ttcatttata cacctctaaa actgtatcta ttgatttttc ttacataaat
    26401 ttaaaattac tatttgttaa tttcatataa gttgatatac tgaatgcatt aacaaagtct
    26461 attcatttta tagttgatat gtatcaacta aatctaagtc tgtttacagt gtaccaagac
    26521 aaaccatagt ttgtacatag caaaataata tattttagaa aagaggtatt ttcatgaagc
    26581 aacaaaaatt attagtctgt ttgctttcaa cttctttact tattccatca ttttctatca
    26641 acgatgttag tgccgaatct ttagaaaaaa gtgccacaac ttctgaatca aatgacgtgt
    26701 ataaggaaaa agatgaggag caagctaagc aatcacattc atcaaaaaat ggaaatgatg
    26761 aaaagaataa agctagtgat gaaaaggaaa atagtgaacg caagagtaag ttaaatagta
    26821 caaaagatga aaggactaca gaagatatta ataataaaag acataaaact tctgataata
    26881 aatcatccaa tgaaaaaata ccaagttcat ttgaaaattc atttaatgat tcatcgtctt
    26941 atgatagttt gaatgttttc aagccagaac cttttaggag tgacaaggat gggctatctg
    27001 aattattaaa tcaactgttc tctaataata aaatgaaaca aacttctact atagagaata
    27061 acgatgtaca aaacgagaag aatgacagtc acaatgataa tacatctata gatcaaataa
    27121 atccaaatac gacatattcg gatgatagtg acgaatcaaa tactaacaat ttagaaaaga
    27181 atagtgataa gggttcacta caagatgaca ttgatgatgt acagtcatct gagaagtcag
    27241 agaacgatga tatagataat aagtctgaat caaacaaact tccagttgat aaaaatcaaa
    27301 aaaaagatga tggtgagtca aaacaatcct cccaacaaga tcaatcttat gaagaagcaa
    27361 ataatgatgc tgataatcta gacaacaaag ataatgacac acctgctact gaaaacgata
    27421 atgccaacag tgataacgaa aatgctgata aatcagatac aaaatctgac gataaagtat
    27481 tagatgcaat tttagacgag tatagtgaag atgctaaaaa taataaaaaa caatatgatg
    27541 ctcaaaaaga tgatttatca aatggaaata gtaaaagtaa gaaaaataat tctgaaaaac
    27601 aggcatcgaa tacaaatgct aaccctcaat taccgtctga atcacaatta gctaaaaaag
    27661 aaaagccagc tcaatcattt gaaaacgaca taaaccaatc aaacatcaga tctactgcaa
    27721 ctttccaaca attgccaaat ttatcggatg ataataacaa ttctaacgat ataacaatta
    27781 ctgaaagtaa aaatacacga gattttatta aaacagttgc acaagacgct cacgacatag
    27841 gtcaagatga agatatttat gcatctgtta tgattgccca agccatatta gaatctgact
    27901 caggcactag cgatcttgct agttcacccc atttcaattt atttggaata aaaggagctt
    27961 atgaaggtca gtcggctaca tttaatacac tcgaagataa tggcaaccat acgttccaaa
    28021 tttcagcaaa cttccgcagc tatccaagca aaaaagaatc attggaagat tatgccaatt
    28081 taatcaaaca cggcatcgat ggtaaccagg acatttataa accaacatgg aaaagtgaag
    28141 cttatagtta ccgttcagca acaatgcatt tggctaccac atacgcgact gattcacaat
    28201 acgcggacaa attaaatagt attatcaacc actatgactt aacacagttt gataataaaa
    28261 aaatgcctga tttagataac tacaaagcga acaacgatga ttatgattca gccttcaaac
    28321 cattttcaga aacaacaaat gactctcctt atcctcatgg gcaatgtaca tggtatgttt
    28381 ataatcgcat ggcacagttc gacaaatatg tgagtggtga tttaggcgac gcacgaaact
    28441 ggaataatcg agcagaaaga aaagattatg ctgtttcttc aacaccaaaa gctcacactg
    28501 ccgttgtatt tgaggcaggt caacaagggg cagaccagat ctacggtcat gtagcttttg
    28561 tagaaaaagt taacgatgat ggttctatcg ttatatcaga atcaaacatt aaaggacttg
    28621 gtatcgtttc ttatagaaca attgatgcag atgctgcaac tgaattgagt tacattacag
    28681 gtaataacta gtaaatttaa atattccttt tattttcttt attaaagtgt ttaatttagc
    28741 ttttattcat tcaaaataca aatgctccat tcaaagttcc acttactagt gttcactttg
    28801 aatggagcat tttcaatata ctatataaat taactcgtac taaaatacgt tataatttaa
    28861 tatttacaat ttttcgattt atttcgtttg atgaaccata ttaatccacc acctataatg
    28921 aaaagtagaa tccctaatgg aattgttgat ttttttacta ctgttcctgt atcaggtaaa
    28981 gaaaaatcac cattattgtc aaataaacca cttaaaaagc tacccgagga atcacctaga
    29041 gataaagcac gcccaggcga aggattagat atatccttaa ttccatctaa tatactgttt
    29101 ctattgaata aatcgtcaaa tagacttggt gtaccaagta attttgaatt tccacttaat
    29161 tttcgcatct gttcagctct gtctaacaaa ctcccatcaa atttattaga taaacttggc
    29221 gtatatttta atggttcaaa caaaccatgc atatcatctt taaatttact tatgtcttta
    29281 tcagccttta atagatcatt caactcatta ttaattcccg atttcattag atttaataag
    29341 ttatgcttag aatcttcttt tttggcaata acgtcagcaa gcgctttagc tttagcatca
    29401 tttaatttcg tagctagcat tgtttctaaa gctttacgtt tatcatgaga ttggtccaat
    29461 atattttcta aaatatcatc acttgtaaca ttgtccccaa aatgatgttt gattaaagct
    29521 acaatttgtt cgttactagg atttttatgc attatttcat caacgatttt tgatgtatct
    29581 atatgatcaa atttagttaa tagaattgtt ttaataagtt cttgcttatc agatgtttta
    29641 tcaaacatag attttaaaat atcatcactc gtagtagtag ataagttatc taactcacta
    29701 acaacttgac tcgcg
//
