LOCUS       NZ_CP054370            33974 bp    DNA     circular CON 13-JUN-2023
DEFINITION  Escherichia coli strain SCU-115 plasmid pSCU-115-2, complete
            sequence.
ACCESSION   NZ_CP054370
VERSION     NZ_CP054370.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14943543
            Assembly: GCF_013315735.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33974)
  AUTHORS   Stephens,C., Arismendi,T., Wright,M., Hartman,A., Gonzalez,A.,
            Gill,M., Pandori,M. and Hess,D.
  TITLE     Title: F plasmids are the major carriers of antibiotic resistance
            genes in human-associated commensal E. coli
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 33974)
  AUTHORS   Stephens,C., Arismendi,T., Wright,M., Hartman,A., Gonzalez,A.,
            Gill,M., Pandori,M. and Hess,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2020) Biology, Santa Clara University, 500 El
            Camino Real, Santa Clara, CA 95054, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 70x
            Sequencing Technology :: Illumina MiSeq, Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/13/2023 04:44:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,958
            CDSs (total)                      :: 4,842
            Genes (coding)                    :: 4,633
            CDSs (with protein)               :: 4,633
            Genes (RNA)                       :: 116
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 209
            CDSs (without protein)            :: 209
            Pseudo Genes (ambiguous residues) :: 0 of 209
            Pseudo Genes (frameshifted)       :: 100 of 209
            Pseudo Genes (incomplete)         :: 133 of 209
            Pseudo Genes (internal stop)      :: 60 of 209
            Pseudo Genes (multiple problems)  :: 70 of 209
            Pseudo Genes (short protein)      :: 3 of 209
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054370.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33974
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="SCU-115"
                     /isolation_source="rectal swab from healthy college
                     student"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pSCU-115-2"
                     /geo_loc_name="USA: California"
                     /collection_date="2015"
     gene            21..308
                     /locus_tag="HPE48_RS24295"
                     /old_locus_tag="HPE48_24280"
     CDS             21..308
                     /locus_tag="HPE48_RS24295"
                     /old_locus_tag="HPE48_24280"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001098466.1"
                     /translation="MNTTLVVLVLAITGALYLPWRLVRDGYKELVQMCLFCSCIVTLAA
                     VYAVLVNLDTPHPFMPMFIAVTAFGAAFVADCALSLWLYQRKANAKTANH"
                     /name="hypothetical protein"
     gene            344..586
                     /locus_tag="HPE48_RS24300"
                     /old_locus_tag="HPE48_24285"
     CDS             344..586
                     /locus_tag="HPE48_RS24300"
                     /old_locus_tag="HPE48_24285"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042036420.1"
                     /translation="MGNIILMAEKAKGAIDEEAEVYEFEGMDDLIQFRKKFPEQMKYEY
                     HYILSGDTKNFRHIALVEANHFKQFKKLVNLYQDR"
                     /name="hypothetical protein"
     gene            739..894
                     /locus_tag="HPE48_RS24305"
                     /old_locus_tag="HPE48_24290"
     CDS             739..894
                     /locus_tag="HPE48_RS24305"
                     /old_locus_tag="HPE48_24290"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021536821.1"
                     /translation="MKKFICNRNGKAVFQEGDRELVAAYQMKSSPVPVTPRKLKAEMEA
                     IARTAR"
                     /name="hypothetical protein"
     gene            complement(1014..1784)
                     /locus_tag="HPE48_RS24310"
                     /old_locus_tag="HPE48_24295"
     CDS             complement(1014..1784)
                     /locus_tag="HPE48_RS24310"
                     /old_locus_tag="HPE48_24295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="WP_039026342.1"
                     /translation="MIIPTQETYDELQRAYEFFNQRLFESALPPCLITLQREKRTYGYF
                     SNGRFVGRSTGQIVDEIAMNPVYFSIRTIRDTLSTLVHEMVHQLQQHTGKPGRRGYHNK
                     EWAAMMERIGLIPSDTGQPGGKRVGESMSHYIEDGGAFDTACKELLTTEFKLSWLDRFP
                     PHKPTPPTPTGADGKGYVDDEDYGDEGYGDDGELDDEITQALSLVNPPPDTPVNKSNRK
                     KYTCPKCHTNVWGKPGLILYCGGEHCGKAEYQPT"
                     /name="SprT-like domain-containing protein"
     gene            complement(1998..2366)
                     /gene="stbC"
                     /locus_tag="HPE48_RS24315"
                     /old_locus_tag="HPE48_24300"
     CDS             complement(1998..2366)
                     /gene="stbC"
                     /locus_tag="HPE48_RS24315"
                     /old_locus_tag="HPE48_24300"
                     /inference="COORDINATES: protein motif:HMM:NF041291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbC"
                     /protein_id="WP_015345231.1"
                     /translation="MEKQPDKLDILMDWFLGDAKEITSKLESVTTSVTETVERLDKASD
                     EIKKSSEVAKTEVIASQRELVNTLKKEQKVSDQFFERLAGAQTGFSQALIRQILIITVV
                     CSFVGGALGAAAITFLLH"
                     /name="stbC"
     gene            complement(2368..3078)
                     /gene="stbB"
                     /locus_tag="HPE48_RS24320"
                     /old_locus_tag="HPE48_24305"
     CDS             complement(2368..3078)
                     /gene="stbB"
                     /locus_tag="HPE48_RS24320"
                     /old_locus_tag="HPE48_24305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="StbB family protein"
                     /protein_id="WP_147701604.1"
                     /translation="MKIAVMNYSGSVGKTIISSYLLYPRMAGAKFFAIETINMSAADLG
                     VDEVMSLTGDNFGQLIEEIVFEDNAIVDIGASNVERFLSTMTKYEGAIDEFDKYLIPVT
                     PDDKAWQESIKTALALSVAGVPKSKIILLPNRIKSTPQEDIASVYEWAKDSKKASIHKD
                     AAVFESEIYEYLAYHKISFEELLAEDPETFKAKAKSCTDADERAAAARRYRWMKLALPV
                     KRNLDRTFEILTAE"
                     /name="stbB"
     gene            complement(3091..3525)
                     /locus_tag="HPE48_RS24325"
                     /old_locus_tag="HPE48_24310"
     CDS             complement(3091..3525)
                     /locus_tag="HPE48_RS24325"
                     /old_locus_tag="HPE48_24310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_065407734.1"
                     /translation="MKKATELEPRNLSAAVRTRLDEIEGWLDKGVSRQEIAQLLDAEYS
                     FSVTPKALEMALYRARLKRKKGGLHNPESTVKNGLHYPKPQEEAKLEDTGLHNPESEKL
                     VEDMGGNKEFLSDTDFEKIGDEAKKVVSSFKGSVGNKKGF"
                     /name="hypothetical protein"
     gene            4000..4347
                     /locus_tag="HPE48_RS24330"
                     /old_locus_tag="HPE48_24315"
     CDS             4000..4347
                     /locus_tag="HPE48_RS24330"
                     /old_locus_tag="HPE48_24315"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_047929023.1"
                     /translation="MPSISLRVTEEQKIDLEYRSEGNVSEYIKQQLFGQKESASEVIAR
                     LDKLLKRSSSEQQAAGRDRYIEAMLIEVLLILRQVSKADAQKVAGGEIRRLGLEPWSAE
                     LAREREEQSHE"
                     /name="hypothetical protein"
     gene            4340..5917
                     /locus_tag="HPE48_RS24335"
                     /old_locus_tag="HPE48_24320"
     CDS             4340..5917
                     /locus_tag="HPE48_RS24335"
                     /old_locus_tag="HPE48_24320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system DNA-binding
                     domain-containing protein"
                     /protein_id="WP_047929022.1"
                     /translation="MNEADKGKICLGALLFTPLVTWFISAKALYGFTPKDARERLVLLI
                     QQTFDLWPLWGALLVGEIIAIIGLIIFFKFNHQIFKGAPFKKIYRGTRLVSQRALASIT
                     KEREPQITIADIPIPTKAEGTHISIAGATGVGKSTIFAEMMKCCLMRGKKQRIASNKDR
                     MIILDPDGDFLSRFYKKGDKILNPYDARTEGWVFFNEIKSDFDFERFGVSIVPTAKDSQ
                     TEEWNGYGRLLFTEVSRKVFNTSRNPTMEEVFYWTNEVPLEELEEYVRGTKAQALFAGS
                     GRAVGSARFVLSNKLAAHLKMPAGNFSIREWLEDPKGGNLYITWTDEMREALKSLISCW
                     TDSIFSIVLGMSKSNSRKIWTFIDELESLDYLPSLRDALTKGRKKGLRVVTGYQSYSQV
                     ISIYGSDVAETLLSNHRTSVVMAAGRLGERTLEFVSKSLGEIEGEREKTGISRRFGQLG
                     TKNTNDDHKRERAVTPTEIATLDDLTGYIAFPGNLPVAKFETHHVNYTRSNPVPGVVLR
                     ESTAFAGM"
                     /name="type IV secretion system DNA-binding
                     domain-containing protein"
     gene            5920..8826
                     /gene="mobF"
                     /locus_tag="HPE48_RS24340"
                     /old_locus_tag="HPE48_24325"
     CDS             5920..8826
                     /gene="mobF"
                     /locus_tag="HPE48_RS24340"
                     /old_locus_tag="HPE48_24325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932317.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobF family relaxase"
                     /protein_id="WP_033544595.1"
                     /translation="MLNITTITRQRVDKVVDYYADGADDYYAKDGNAMQWQGAGAEELG
                     LTGEVEQKRFAKLLDGKVTDDISVMRKTANSESKERLGYDLTFSAPKGVSLQALVNGDK
                     RIIEAHDRAVTKAIEEAERLALGRFTVNKKTHVENTNKLIVGKFRHETSRELDPDLHTH
                     AFVMNLTKTSDGKWRSLTNDGIVNSLTLLGNVYKSELARELELAGYNLRYDRNGTFDLA
                     HFSQEQIAQFSQRSQQIEAELAKNGLSRETASHELKNAAALKTRKSKGEVDRDVLYEGW
                     KNRAKELQIDFDSREWKGAANDDIARNTQPAALEKPIEYQADKVMTFAIRSLTERQSVI
                     TERELMDVAMKHGYGRLTLDDIRAARERAITSGNLIKEEATYAAATTNKKQQNVAMTRE
                     QWVTELVKAGRSKDEARKLVDKGITNGRLVQQKPRFTTQLAQQRERNILKMEREGRGKI
                     QTPYTREFSEGWLASRTLKPEQLKAVMGIIHTPNQFISVHGFAGTGKSYMTKSAADFLK
                     EQGVHVTSLAPYGSQVKALQAEGLESRTLQSFLRASDKKIGPGSVVFIDEAGVIPARQM
                     EETMRVIRDAGARAVFLGDTKQTKAVEAGKPFEQLIKAGMETAYMKDIQRQKDPELLKA
                     ALNAAEGKIKASLTHVTSIVEEKNHDQRYRRIVGDYVAMPPTDRANALIITGTNDSRKK
                     INEYIQAELGLKGQGINYPLLNRLDTTQAQRQHSKYYEKGAVIIPERDYSNGLKRGAVY
                     TVLDTGPGNKLTVSDGSGDTIAFSPARFSKLSVYSVEKTELAVGDQVRITRNDAHLDLA
                     NGDRFKVKSVQSGEVLLENEKGRLVKIDANKPMYLGLAYASTVHSAQGLTCDKVFINMD
                     TRSLTTAKDVYYVAVTRAKHEAVIYTDDEKKLDKAASREGFKTAALELEQLKRYAKEQQ
                     HDTREKGRDKAEPTQDKGNARPKDKGHEKNNDDRALRL"
                     /name="mobF"
     gene            8836..9123
                     /locus_tag="HPE48_RS24345"
                     /old_locus_tag="HPE48_24330"
     CDS             8836..9123
                     /locus_tag="HPE48_RS24345"
                     /old_locus_tag="HPE48_24330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000983081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_033544594.1"
                     /translation="MTVRLYYNAADSRAKASAEWHDNWISKSGLKARYWTDKAISDFLD
                     QPQKAGPIMAWKRKDVLKVESTSEFQQWMAKRRRWLIAHGKLLAEDLPSK"
                     /name="hypothetical protein"
     gene            complement(9397..9591)
                     /locus_tag="HPE48_RS24350"
                     /old_locus_tag="HPE48_24335"
     CDS             complement(9397..9591)
                     /locus_tag="HPE48_RS24350"
                     /old_locus_tag="HPE48_24335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_033544593.1"
                     /translation="MGQGINTLSLELDDKEALALAQFVKRLTWSDLRGGAVDDDEAYVI
                     KDAVDKLQRAMAEEGFSPR"
                     /name="hypothetical protein"
     gene            complement(9603..10085)
                     /locus_tag="HPE48_RS24355"
                     /old_locus_tag="HPE48_24340"
     CDS             complement(9603..10085)
                     /locus_tag="HPE48_RS24355"
                     /old_locus_tag="HPE48_24340"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="WP_033544604.1"
                     /translation="MLDMRLGNSGDIPFIMNLVRDGVISGAFFYAEGNGLETVRSELQS
                     VTQQYRDNIPVGDYLFVFAEKLTRQPVGFSLLTGRNDFAGRASHLEIRMFAVAADEQGK
                     GIGKSMLASIIEATPGHRLEASCLPPATKMMRLLAGSGFKLIHETQGGKKTYRFTD"
                     /name="GNAT family protein"
     gene            complement(10098..10652)
                     /locus_tag="HPE48_RS24360"
                     /old_locus_tag="HPE48_24345"
     CDS             complement(10098..10652)
                     /locus_tag="HPE48_RS24360"
                     /old_locus_tag="HPE48_24345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="WP_042036424.1"
                     /translation="MIQHLKKRNFLFKAALVAAVLYGASAPSLFAASAQVGFSPEGTAQ
                     QLVINVIGSAKDNIRMMAYSFTAPDIMKALIAAKRRGVDVKIVVDENGNTGRASRAAMN
                     LVTNAGIPLRVNSNYKIQHDKVIIVDGRHVETGSFNYTASAEKYNSENAIVMWDAPELA
                     GQYLKHWQSRWNQGRDFTPSY"
                     /name="phospholipase D family protein"
     gene            complement(10615..11646)
                     /gene="virB11"
                     /locus_tag="HPE48_RS24365"
                     /old_locus_tag="HPE48_24350"
     CDS             complement(10615..11646)
                     /gene="virB11"
                     /locus_tag="HPE48_RS24365"
                     /old_locus_tag="HPE48_24350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138004.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_033544592.1"
                     /translation="MTELTSNIQDIRQRPRREQGVWLTLEPLQRYLSDPDVWELRINKY
                     QQVVCETSKGRIFHDDEKITAEYISRLTDTLCGYNGLPKESVNNVLLPDGSRGIICLPP
                     AVLEGTVAIAFRKHLPVDKSLEQLRDEGRFTGWKRKIQGEVALQPFEQELLELLDKDDL
                     VSFFKIAVRNKLNIVVSGSTGSGKSTFTRSLLREVPYTERIVVSEDVHEIGSDLHHEMV
                     YMLYGDQDGRLAPAVSLKACMRLSPDRIMMTELRDDAAWDYINSLNTGHPGGITSTHAD
                     DAKSTFSRIALLIKQTGVGQTLDYDVIMKTLYTTIDVVVYMEHRQIVEVLYDPAFKKAQ
                     LSL"
                     /name="virB11"
     gene            complement(11639..12793)
                     /gene="virB10"
                     /locus_tag="HPE48_RS24370"
                     /old_locus_tag="HPE48_24355"
     CDS             complement(11639..12793)
                     /gene="virB10"
                     /locus_tag="HPE48_RS24370"
                     /old_locus_tag="HPE48_24355"
                     /inference="COORDINATES: protein motif:HMM:NF038091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein VirB10"
                     /protein_id="WP_050008676.1"
                     /translation="MRKDREENLDYLDEEDTSIEDERQGFSGSPKKRIAGARAFVGLMV
                     LIGSAMVGWFIYNQMHVKKLADDPKKGKEQVMTSSLPRQSFDDVPPTIDNTPKNSVVPP
                     LQTTQEPQQQVARQTLNNQKKELTPEEKIMRARLGVSFNGVDPEKQATTAKEQERRSGQ
                     DNTETSSNSQALASRMKPARMAVAQASVMPHPNLTIAQGTMIPCGTNTELDTTVPGQVK
                     CTVSRDVYSADGTVKLIDKGAVVTGEQNSGIQNGQNRVFVLWSRLRNPDQTIVNLDSSG
                     TNALGSAGVPGQVNSHFWERMGDAIFFSVLTDGMKAGIASINNNNSDVTFNTTENSTDQ
                     LATEALRAKINIPPTLYAAQGDAVSIYVARDLDFSTVYGLEMND"
                     /name="virB10"
     gene            complement(12790..13677)
                     /locus_tag="HPE48_RS24375"
                     /old_locus_tag="HPE48_24360"
     CDS             complement(12790..13677)
                     /locus_tag="HPE48_RS24375"
                     /old_locus_tag="HPE48_24360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_033544590.1"
                     /translation="MKKQLIAGLILVSLGLSGQALALEVGKGSPYDYRIKSVVYNPVDV
                     VRIDSVAGVATHIVVAPDESYVTHAFGDSNSYAFTHVENNIFIKPKGEVPSDTNLVLVT
                     NKRTYNIVLHYVGDYTTKDAQGNVKANFIKTPWSMKNATLQLTYLYPFEDMKKANKTLE
                     SNRVKKALKDLQNGPYNLLYKMSDEDEYRTLAPVNVWDNFRFTYFKFPANADLPVVFYI
                     GDDGKEHTVNQHPAGEYNNIVVAETVAKEWRIRYGNKVVGVLNMNYNPNLGAISTGTTS
                     PDVKRVKKGEGDKS"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            complement(13680..14396)
                     /locus_tag="HPE48_RS24380"
                     /old_locus_tag="HPE48_24365"
     CDS             complement(13680..14396)
                     /locus_tag="HPE48_RS24380"
                     /old_locus_tag="HPE48_24365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001642190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000914645.1"
                     /translation="MLKKNKHQAISREDLNKYHEETQGLERDMVNEILNSRSRAWKIAT
                     AFFVFAVVSMITAVGVIIRFAQPLPAYLTTINKDTGEVSQVKITRDEATYGDVIDQYWI
                     SQFVIHRESYDYNSIQVDYDAMSLMASGDVADEYLSMFKGPNRIDKRLGDSERTTVHIN
                     SVITDREHGVATVRFTTQQRIRQRPNPEPPRYWIATIAYEYKALPMTAQQRYINPLGFR
                     VTSYRKNAENVGAVGG"
                     /name="type IV secretion system protein"
     gene            complement(14399..14569)
                     /locus_tag="HPE48_RS24385"
                     /old_locus_tag="HPE48_24370"
     CDS             complement(14399..14569)
                     /locus_tag="HPE48_RS24385"
                     /old_locus_tag="HPE48_24370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021536809.1"
                     /translation="MVHFFKYTAMALIGLLLAACSSSPTPPPEPNMKKLVDVNKTYPAE
                     LYRADAANNGE"
                     /name="hypothetical protein"
     gene            complement(14664..15671)
                     /locus_tag="HPE48_RS24390"
                     /old_locus_tag="HPE48_24375"
     CDS             complement(14664..15671)
                     /locus_tag="HPE48_RS24390"
                     /old_locus_tag="HPE48_24375"
                     /inference="COORDINATES: protein motif:HMM:NF016491.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_170913282.1"
                     /translation="MDTVTKEFVASNLGVVISTISPVIGLALICKLTLDGLFTLARPHG
                     EPLSSLIKKFIVWSMIISFASAGGLYQTQLADAAMKIPDEFSSVLVINGSSGGTEDAMG
                     NNIDKAIHDGMQVARTAFDNADIYSGSGLASLFLACAVIISTVLICGIGAGLVLMAKLL
                     LAITVCFGPIFIFCLLFKPLYGMFNKWLGSMVNYGLVTILLSMLFGLMIKFYQKALDAV
                     TASGADSSLLGPVFACLLIMIVSYLILMRIPEVASRWGDGISAGIQELIPNAGGGGRGA
                     GGGGYQPGGQKGATGAGGGTGAKTAAATAAGGPGAGAATAAGSQMQGFAKGSRR"
                     /name="type IV secretion system protein"
     gene            complement(15726..15962)
                     /locus_tag="HPE48_RS24395"
                     /old_locus_tag="HPE48_24380"
     CDS             complement(15726..15962)
                     /locus_tag="HPE48_RS24395"
                     /old_locus_tag="HPE48_24380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_033544588.1"
                     /translation="MKKLILPLALFLLAGCDSEHPVSWYKEHDQERKAMVEKCRDDAAL
                     KVKPDCQNALEAEKDLKVFGKNDDGLSMPKVTP"
                     /name="EexN family lipoprotein"
     gene            complement(15966..16673)
                     /locus_tag="HPE48_RS24400"
                     /old_locus_tag="HPE48_24385"
     CDS             complement(15966..16673)
                     /locus_tag="HPE48_RS24400"
                     /old_locus_tag="HPE48_24385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_047929021.1"
                     /translation="MKKTLASLVLALAISPVAVNAQLVVNDPANLAQALEQVTLMTQQI
                     EQLKSQLLKQEQTLASLTGSSGIGNLLNDDISTLKGNLPSDWTQVYSDAMNSSSGITSS
                     AQSMLKEFQSQIDGMNRSEAMSFIKQKLAEKGAYDRVMAQNAYNNEMAELNNIQELTNQ
                     IDSTTDMKQIADLQARIQTAQGAIQGEQTKLQLMAMLQTSQDKILQEQKQYAQKRFVLG
                     ADGEDLSMPNVTE"
                     /name="type IV secretion system protein"
     gene            complement(16683..19313)
                     /locus_tag="HPE48_RS24405"
                     /old_locus_tag="HPE48_24390"
     CDS             complement(16683..19313)
                     /locus_tag="HPE48_RS24405"
                     /old_locus_tag="HPE48_24390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_033544586.1"
                     /translation="MAVAEMKKRGVKDFKKEPSSLKYIPYSYHVTPHVISTVNGEYLSI
                     FKIRGRTHDCASDAELIKWHADLNQLLKGIGSEHVKLWTHLHHREINNYPDTHYNMTFP
                     RMVNEYYRDQFDDTPMMVNDLYLTVVYNPVGDAAQKMLAKFDKPSASELREMQADAIGA
                     LEDICEQVMNSLRPYGIDRLGYYFRDKRGNVIPEQKKDDAEDDEDIIDLREDLLADVEY
                     QDVQEDKEVFSGTQHTYSKALEWLYYLVNGEWAPVPVCRGRIREYLATTRPISSFWGDG
                     IEIRGTDERRYTSAVEIRDYDSDTEPGQINILMEAPFEFVLTQTYCCMSQQAARTYLTN
                     QQKALLETGDPSFTQINQMSDAVDGVVSRTFIMGWHHLTVHTFGKTLKEARSNAGVARN
                     MLNNCGLIASQVGLASEAAYYAKLPANQHLSPRPCPLNSWNFLCFSPFHNFMSGKANNN
                     PWGPALTLFKTVANTPLYMNLHVTPEDEMSFGKRPLAHTLMLGRSGAGKTTLLNFLLTQ
                     AMKYNPRIFAFDRDQGMMPMIKALHGHYTVLKEGVASGWAPLQMPGTKVNIAFCKRLMR
                     LCAEITKGSVLDADQVNDLNRAVDALMDENSLIPTDLRTVDMLIQQMPNPYQTAGSKQT
                     LASLLVPWTRGHENGWLFDNDSDSLNLGEYDIYGFDLTDFIVADNEIPPATRTPLLMYL
                     NFRVRQSIDGRRRVIQVFDEFHQYLDDPIMSVEVKRGLKTDRKKDAVYVFSTQEPNDAL
                     DSSIGKTIMQQCVTKILLENPDADYEDYVTRLKLTPAEFDALLSIPENSRQFLVKQGSQ
                     SAMAQFNLAPRVKTPENFRKLDKILSILSGETQNAETLAKIIEQIGDDNPDKWLEPYWK
                     SVLAA"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            complement(19313..19627)
                     /locus_tag="HPE48_RS24410"
                     /old_locus_tag="HPE48_24395"
     CDS             complement(19313..19627)
                     /locus_tag="HPE48_RS24410"
                     /old_locus_tag="HPE48_24395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_033544585.1"
                     /translation="MNLSGKYPLFKGATRLPTFAGVPRTVIIATFIFCATLFMTIHLWA
                     LVLFGLLWFIEFCISKHDDRMFRIIWLAIMTKGLNMINSPFTKLWGGSSYSPTDYGDKK
                     "
                     /name="VirB3 family type IV secretion system protein"
     gene            complement(19679..19969)
                     /locus_tag="HPE48_RS24415"
                     /old_locus_tag="HPE48_24400"
     CDS             complement(19679..19969)
                     /locus_tag="HPE48_RS24415"
                     /old_locus_tag="HPE48_24400"
                     /inference="COORDINATES: protein motif:HMM:NF016820.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_033544584.1"
                     /translation="MNTAIKRFFPVAMFMMVALCVPELALAAGADTGESSMNSVNSWLM
                     TWIPVAATVLIIVSAIAWIAHMLPASWAVRIVVGLIVVGSASYLVGLFGLS"
                     /name="TrbC/VirB2 family protein"
     gene            complement(19953..20270)
                     /locus_tag="HPE48_RS24420"
                     /old_locus_tag="HPE48_24405"
     CDS             complement(19953..20270)
                     /locus_tag="HPE48_RS24420"
                     /old_locus_tag="HPE48_24405"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050008675.1"
                     /translation="MRVYLILLKQLEEVFNQNKVVRIAIQRMDKKKWIPLFDVKNSEGG
                     VITCSLRVQSGEGVRTWADLRILADMLRDDFNAREVGLFLDEPDFIFPDDGVLEKDEYS
                     D"
                     /name="hypothetical protein"
     gene            complement(20293..21033)
                     /locus_tag="HPE48_RS24425"
                     /old_locus_tag="HPE48_24410"
     CDS             complement(20293..21033)
                     /locus_tag="HPE48_RS24425"
                     /old_locus_tag="HPE48_24410"
                     /inference="COORDINATES: protein motif:HMM:NF013618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_033544583.1"
                     /translation="MKQVVALFPLLIAGLLDATSANAELSAPVMALAKRCAPEVHPLTI
                     GYLVSHESRNNPYAINVNVPKGTKSPLARQPRTLDEAVKTTKWLTAHGYNFDVGLGQIN
                     SANFPKLNVSAADLFNGCKNLEAAQYVLNYCYQLATKEYAPGQSALRHALSCYNTGSLT
                     AGFTNGYVSKVVAQIGQSKPVIPALKADDGSTDVKSVDTAIDAVPVDAADGEEKPKDAG
                     MTDAFGGSDKDAFGASDGDAFRQK"
                     /name="lytic transglycosylase domain-containing protein"
     gene            21096..21329
                     /locus_tag="HPE48_RS24430"
                     /old_locus_tag="HPE48_24415"
     CDS             21096..21329
                     /locus_tag="HPE48_RS24430"
                     /old_locus_tag="HPE48_24415"
                     /inference="COORDINATES: protein motif:HMM:NF013014.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS histone family protein"
                     /protein_id="WP_033544582.1"
                     /translation="MSRQDEKKHKTEQERETSVPKRKIIFVPLQSEKSPKGEPRYRDPA
                     NPFNTWVGRGKRPDWLKKYLDEGRELSEFEIG"
                     /name="H-NS histone family protein"
     gene            21344..21781
                     /locus_tag="HPE48_RS24435"
                     /old_locus_tag="HPE48_24420"
     CDS             21344..21781
                     /locus_tag="HPE48_RS24435"
                     /old_locus_tag="HPE48_24420"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_033544581.1"
                     /translation="MSKIIDFPTGKKRERRAKAIRAQRDKEAMQRSKIATSQFWWANKI
                     KLLTVIKQSVRFLLIYLGLLATDIFIYLVFILGKLLKFFAMTGIIAALLFLVMEYRNGW
                     HYTQSIFHAAAIFFGLIALRIGHDKLLNGLIRLKSYLSRKG"
                     /name="hypothetical protein"
     gene            21880..22101
                     /locus_tag="HPE48_RS24440"
                     /old_locus_tag="HPE48_24425"
     CDS             21880..22101
                     /locus_tag="HPE48_RS24440"
                     /old_locus_tag="HPE48_24425"
                     /inference="COORDINATES: protein motif:HMM:NF019069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_226426390.1"
                     /translation="MAAKSGGEFGSVGDSDCSGAIADFFNIVKKNKHGFRPGKTSDARK
                     QFLMECSGAQENTAAVNRVISMFGRVKG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            22105..22419
                     /locus_tag="HPE48_RS24445"
                     /old_locus_tag="HPE48_24430"
     CDS             22105..22419
                     /locus_tag="HPE48_RS24445"
                     /old_locus_tag="HPE48_24430"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_033544579.1"
                     /translation="MKIKSILFTTVLLLSGCASQSQVEQLSKQVNTLKTDLYNLQIQQR
                     NDTQALQREVQKSRPIGVCYLDGHPYSQGAVIAGRICASNGVIVNGKPTEVSWQVYHRR
                     "
                     /name="hypothetical protein"
     gene            22395..23099
                     /locus_tag="HPE48_RS24450"
                     /old_locus_tag="HPE48_24435"
     CDS             22395..23099
                     /locus_tag="HPE48_RS24450"
                     /old_locus_tag="HPE48_24435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000353823.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004519 - endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="WP_236489649.1"
                     /translation="MAGLSPPLTTRVRGFGPVFYGTGSMDILSLFPPNVIALWAVSFGF
                     LAVLYWWKITARKRRHKRKQQQARRVLAKIQTLPAFGYKIAYLRKIDPFTFEELLLEGF
                     ESHGFRTIRNKRYTGDGGIDGQVIIGKHRYLIQAKRYRGHIALQHVQEFDTLLKRHNCR
                     GLFCHTGKTGAASKAVSFASDRMEIISGQRLIDLLTPGSSFTIATAPQTMMRRTAATRG
                     TNIIVEEADKET"
                     /name="restriction endonuclease"
     gene            complement(23156..23482)
                     /gene="mazF"
                     /locus_tag="HPE48_RS24455"
                     /old_locus_tag="HPE48_24440"
     CDS             complement(23156..23482)
                     /gene="mazF"
                     /locus_tag="HPE48_RS24455"
                     /old_locus_tag="HPE48_24440"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease MazF"
                     /protein_id="WP_075335266.1"
                     /translation="MKRDYIPDAGDIVWIDFNPQAGHEQAGHRPALVLSPAVYNGRIGL
                     LLCCPMTTKIKGYPFEVRNGEGSAVLADQVKSLDWRKRGAVKKGKVSAAVLAEVRSKLK
                     VLIG"
                     /name="mazF"
     gene            complement(23472..23729)
                     /locus_tag="HPE48_RS24460"
                     /old_locus_tag="HPE48_24445"
     CDS             complement(23472..23729)
                     /locus_tag="HPE48_RS24460"
                     /old_locus_tag="HPE48_24445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_075335265.1"
                     /translation="MLNFLKKIYSYLEFLGALIWVGVGLYSIWLGFGKLFKDNSISIGG
                     VEAVSLLDTTPFAIMFIFCGVLIITFIWVGYISKRLKNEA"
                     /name="hypothetical protein"
     gene            complement(23803..24048)
                     /locus_tag="HPE48_RS24465"
                     /old_locus_tag="HPE48_24450"
     CDS             complement(23803..24048)
                     /locus_tag="HPE48_RS24465"
                     /old_locus_tag="HPE48_24450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195442.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="WP_053901029.1"
                     /translation="MTQVIIKKWGNSLSVRLPSAIVKAASLNVDDVVELSVEDGAITIV
                     PVKTKEYSLDALMAGVTNENIHEEISFGAPVGKELL"
                     /name="AbrB/MazE/SpoVT family DNA-binding domain-containing
                     protein"
     gene            24501..25085
                     /locus_tag="HPE48_RS24470"
                     /old_locus_tag="HPE48_24455"
     CDS             24501..25085
                     /locus_tag="HPE48_RS24470"
                     /old_locus_tag="HPE48_24455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015272392.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_033544574.1"
                     /translation="MKIGYARKSTKEQDTSLEYQIEALQKAGCEKWYAEQVSRGGNKRL
                     KTGTPELENCLKALRAGDTLVVWALDRLGGTLLQLLQLMNELRSKGIHFESLKERIDTQ
                     SPMGEMYYSLIAIFSNFEVARNHERTMAGLAAAKKKGRIGGRKPKLSPQDIKEINALVK
                     SPEITVKEIAARFKVSRPTIYRHISSDIQDE"
                     /name="recombinase family protein"
     gene            25103..25471
                     /locus_tag="HPE48_RS24475"
                     /old_locus_tag="HPE48_24460"
     CDS             25103..25471
                     /locus_tag="HPE48_RS24475"
                     /old_locus_tag="HPE48_24460"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_174144238.1"
                     /translation="MWEPPHVRRALPVWESPHVRRALPVWESPHVCRALPVWESPHVCR
                     ALPVWESPHVRRALPVWESPHVCRALPVWESPHVCRALPVWESPHVCRALPVWEFTPCL
                     PGAADVGESPHVCQALPV"
                     /name="hypothetical protein"
     gene            complement(25829..26047)
                     /locus_tag="HPE48_RS24480"
                     /old_locus_tag="HPE48_24465"
     CDS             complement(25829..26047)
                     /locus_tag="HPE48_RS24480"
                     /old_locus_tag="HPE48_24465"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_174144239.1"
                     /translation="MVIPDTGSARRTWGDSHTGSARRTWGGSHTGSARQTWVIPYTGSA
                     RQTWVIPTPAALRRTWWFHRQRPANMG"
                     /name="hypothetical protein"
     gene            complement(26034..26186)
                     /locus_tag="HPE48_RS24485"
                     /old_locus_tag="HPE48_24470"
     CDS             complement(26034..26186)
                     /locus_tag="HPE48_RS24485"
                     /old_locus_tag="HPE48_24470"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_174144240.1"
                     /translation="MGDSHTEAWRTWGDSYTGSAWRTWVVPTPAAPGKHGVIPTPAVPG
                     KHGDS"
                     /name="hypothetical protein"
     gene            27766..28029
                     /locus_tag="HPE48_RS24490"
                     /old_locus_tag="HPE48_24475"
     CDS             27766..28029
                     /locus_tag="HPE48_RS24490"
                     /old_locus_tag="HPE48_24475"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_174144241.1"
                     /translation="MKITAPAILAWKTAEPGLDGKIRQPHLQPRSSVLMVLSEYSGYAA
                     LATQRIHITTSTIAIIEMRTEKFKQFRLSKGDKSYQPMFPLK"
                     /name="hypothetical protein"
     gene            28629..28898
                     /locus_tag="HPE48_RS24495"
                     /old_locus_tag="HPE48_24480"
     CDS             28629..28898
                     /locus_tag="HPE48_RS24495"
                     /old_locus_tag="HPE48_24480"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000779465.1"
                     /translation="MKLTTLLKKHFDIEEITDVDSTVNREVYTIWVYEKGEDCEPLLIL
                     KDAQDFMGVDGWLVGNIYSTLQHGLLLQHEELKTMIRNGEIKSR"
                     /name="hypothetical protein"
     gene            28987..29202
                     /locus_tag="HPE48_RS24500"
                     /old_locus_tag="HPE48_24485"
     CDS             28987..29202
                     /locus_tag="HPE48_RS24500"
                     /old_locus_tag="HPE48_24485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000111575.1"
                     /translation="MSVKDFTPTLEIKFHRRRWRIMVGRSSLASFRSEQDAIDALNKRR
                     SFYEYWAGSAGVQAENTEPVIVHVTY"
                     /name="hypothetical protein"
     gene            29389..30216
                     /locus_tag="HPE48_RS24505"
                     /old_locus_tag="HPE48_24490"
     CDS             29389..30216
                     /locus_tag="HPE48_RS24505"
                     /old_locus_tag="HPE48_24490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011871441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF932 domain-containing protein"
                     /protein_id="WP_024147850.1"
                     /translation="MMLSSRFRSANILRSDRPLNDDQIMRYAPSIFATEAHESRSDRYA
                     YIATSEVLNGLRDNGFHPFMVCQTRVRNLDKREHTKHMIRLRHAGQINGTEAKEIILLN
                     SHDGSSSYQMLAGVFRFVCHNGLVCGDTVADIRIPHKGNVTERVIEGAFEVLDQFDNVE
                     NHMDAMKSVTLNALEKRIFADAALALRYDEKDGPAPIAASQLLEARRFEDRKDDLWTTF
                     NRVQENIIRGGLSARTKQGKSTRTRAVTGMDKDTSLNRALWILSERMNELKAA"
                     /name="DUF932 domain-containing protein"
     gene            30273..30746
                     /locus_tag="HPE48_RS24510"
                     /old_locus_tag="HPE48_24495"
     CDS             30273..30746
                     /locus_tag="HPE48_RS24510"
                     /old_locus_tag="HPE48_24495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_033544285.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQ
                     TGEMKEQTEWHRVVLFGKLAEVAVEYLRKGSQVYIEGQLRTRKWTDQAGVEKYTTEVVV
                     NVGGTMQMLGGRSQNASQTGNQPQGGQQFSGQPQTTGTAAGNESPPFDADIPF"
                     /name="single-stranded DNA-binding protein"
     gene            30811..31113
                     /locus_tag="HPE48_RS24515"
                     /old_locus_tag="HPE48_24500"
     CDS             30811..31113
                     /locus_tag="HPE48_RS24515"
                     /old_locus_tag="HPE48_24500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrfB-related DNA-binding protein"
                     /protein_id="WP_000257688.1"
                     /translation="MAVERISPEEWQRIAPALRTCSQVTIDMAYAVLVDGRKQVDVAKE
                     FDRSKQTVNAAIRRVTAIFNEVIPEDEQLEFVQVWLPPELAKQVKEMAKPYQNKN"
                     /name="TrfB-related DNA-binding protein"
     gene            31128..31469
                     /locus_tag="HPE48_RS24520"
                     /old_locus_tag="HPE48_24505"
     CDS             31128..31469
                     /locus_tag="HPE48_RS24520"
                     /old_locus_tag="HPE48_24505"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021536824.1"
                     /translation="MAKVRFENSLNKMIFEIRGYESFSEMETALLDFCDETMGANHPDI
                     VVEYPVYYKHFINDKISYEHIGYVNLGIDQDDGSCYTIEHLTLDRKTLKNHWHPFYFYK
                     GECEYGFKN"
                     /name="hypothetical protein"
     gene            31655..31831
                     /locus_tag="HPE48_RS24525"
                     /old_locus_tag="HPE48_24510"
     CDS             31655..31831
                     /locus_tag="HPE48_RS24525"
                     /old_locus_tag="HPE48_24510"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_156649898.1"
                     /translation="MASPSSASNGAIVPVGALAAARPSPQHPDKSRPARRYAPARPLNR
                     AVVTGHCSGGGIV"
                     /name="hypothetical protein"
     gene            32185..32607
                     /locus_tag="HPE48_RS24530"
                     /old_locus_tag="HPE48_24515"
     CDS             32185..32607
                     /locus_tag="HPE48_RS24530"
                     /old_locus_tag="HPE48_24515"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_110437924.1"
                     /translation="MSAYVVSDKAISTIVKTLVLTGTLQPVEAVSFGQMMLNLNTHSVN
                     VRYQESSPAHAFEYSEPELNINDPKTQIQVIVCIDEYEYQSCEFAEYYETMVHTVLKAI
                     KSALHEAYTETLPNPAQWKAKKSYELPGYSEAAWSL"
                     /name="hypothetical protein"
     gene            33467..33643
                     /locus_tag="HPE48_RS24535"
                     /old_locus_tag="HPE48_24520"
     CDS             33467..33643
                     /locus_tag="HPE48_RS24535"
                     /old_locus_tag="HPE48_24520"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_156649898.1"
                     /translation="MASPSSASNGAIVPVGALAAARPSPQHPDKSRPARRYAPARPLNR
                     AVVTGHCSGGGIV"
                     /name="hypothetical protein"
     Typing          complement(26293..27001)
                     /name="rep_cluster_1760"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="91.18"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5921..8817
                     /name="MOBF"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.447"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          4341..5914
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="97.905"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(12794..13677)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.322"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(13684..14396)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.44e-159"
     Typing          complement(14668..15707)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="93.372"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(16687..19313)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="97.489"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 caacctgcga aggaaaatgt atgaatacga ctcttgttgt tttagtcctc gccataacag
       61 gcgcgttata tctcccctgg cgtcttgtgc gcgacggtta caaagaactg gtgcagatgt
      121 gcctgttttg ctcctgtatc gtcacgctgg ccgctgtata tgccgtgtta gtcaatctcg
      181 atactccaca cccgtttatg ccaatgttta tcgcggtaac ggcgttcggt gctgctttcg
      241 tggctgactg cgctttatct ctctggctct atcagcgtaa agctaacgct aagacggcta
      301 accactaacc actacggttt ctaaccatga tacgggggta aatatgggaa atatcatcct
      361 gatggctgag aaagcaaaag gcgcgattga tgaagaggct gaagtgtatg aatttgaggg
      421 aatggatgat ctgatccagt ttcgtaagaa attccctgaa cagatgaagt atgaatatca
      481 ttacatcctt tccggcgaca cgaaaaattt tcggcatatc gcgcttgttg aagccaacca
      541 ttttaagcag ttcaaaaagc tggttaatct gtaccaggat cgctaacaac gcggaacagc
      601 gcggcattgc cgcgctgctg tataacgtat tatttaagta tcatttaatg atacttaaag
      661 ttgacttttt gagggggaga atttatactg tatttatcgg ttagcaatgg tgctgaccgt
      721 aagcgaagga gcaaggttat gaaaaaattt atctgcaacc gcaacggcaa ggcggttttt
      781 caggaaggtg atcgggagct ggtagctgct taccagatga aatcctctcc ggttccggtg
      841 acaccccgca agctgaaagc tgaaatggag gctatcgcca gaacagcccg ataatcaatc
      901 acccgcgccg ttggcgcggg tatccctcat agcggcggca accgcttttt gcgagcgtaa
      961 cgcgaggacg taaaaactaa aaaaaaccgc ctcatacggc ggtttttttc tggttaggtt
     1021 ggctggtatt ctgcctttcc gcagtgttcg ccaccacagt acaggatcag gcccggcttt
     1081 ccccacacgt tcgtatggca tttcgggcag gtgtattttt tccggtttga tttattcacc
     1141 ggcgtatctg gcggcgggtt taccagcgaa agggcttgtg tgatctcatc atccagctcg
     1201 ccatcgtcgc cgtatccttc atccccataa tcttcgtcat cgacataccc tttaccgtct
     1261 gcgccggttg gcgttggtgg cgttggtttg tgtggcggga accgatccag ccaactcagt
     1321 ttaaactccg tggtaagcag ctccttgcag gcggtatcaa acgcgccgcc gtcctcgatg
     1381 taatgactca tggactcacc gacgcgctta cctcctggct ggccggtgtc ggatggtatc
     1441 aggccgatgc gctccatcat cgccgcccat tctttattgt ggtatccacg gcggcccggt
     1501 ttgccggtgt gttgctgcaa ctggtgaacc atttcatgca caagcgtgga aagcgtgtcg
     1561 cgtatcgtgc ggatcgagaa atagaccgga ttcatggcga tttcatcaac gatttgtccg
     1621 gttgagcgac caacaaagcg accattcgag aaatagccat acgttcgttt ttcgcgctga
     1681 agggtgataa ggcaaggcgg cagcgcactt tcaaataggc gttgattgaa aaattcgtag
     1741 gcgcgttgaa gctcgtcgta agtttcctgg gtagggatga tcatagcggc ctcacaatgg
     1801 atttctggat tgcacaaacc attttattga ttatggattg tgcaatccac ttttattttt
     1861 gggcgttccc tgcgggcggg ctttcgtgct gcgcatcgag ccaggcaagc tgtctcgccc
     1921 cttcgggctt caatccctaa cgcaatcgag gccaaaaaaa acggcccgga tagggccgct
     1981 tcaggtcagg ctttttgtca gtgaagcagg aacgttatag ccgccgcgcc gagcgctcca
     2041 ccaacgaagg aacagacaac cgtgataatc agaatctgcc tgataagcgc ttgcgaaaac
     2101 cctgtttgcg ccccggccag acgttcaaaa aattggtcgc taaccttctg ctccttcttc
     2161 agagtgttga ccagctcgcg ctggcttgcg atcacttctg ttttcgccac ctcagatgat
     2221 ttctttattt catcggaggc tttatccagc cgttctactg tttcggtaac gcttgtggtt
     2281 acgctttcca gttttgaggt gatttctttc gcatcgccta aaaaccagtc catcaggata
     2341 tctaatttat caggttgctt ttccatatta ttcagccgtt aatatttcaa aggtacgatc
     2401 aagattacgt ttaaccggca gcgctaattt catccagcga taacgtcgcg cagccgccgc
     2461 gcgttcgtcg gcatcagtgc aggatttagc tttcgcttta aatgtttctg gatcttcagc
     2521 cagcagttct tcaaacgaaa ttttgtgata cgcgaggtat tcataaattt cactttcaaa
     2581 aacggcggca tctttatgaa tagaggcttt tttagaatcc ttcgcccatt catacactga
     2641 agcaatatct tcctgcggag ttgatttaat gcggttaggt agaagaataa ttttggattt
     2701 tggaacgcca gctacgctta acgcgagagc ggtcttaata ctttcctgcc atgctttatc
     2761 atccggggta acaggaataa gatatttatc aaattcatca attgcaccct cgtattttgt
     2821 catggtagaa agaaaacgct ctacgttcga cgcgccaata tccacgatgg cgttatcttc
     2881 aaatacgatt tcttcaatca gttgaccaaa attatccccg gtcaaactca ttacttcatc
     2941 aacacccaaa tcagccgccg acatattgat tgtctcgatg gcaaagaatt ttgcgccagc
     3001 catgcgagga tacagcaggt atgacgaaat aatagttttg ccgacactgc cactgtagtt
     3061 cattactgca attttcatct attcgctcct ttagaaacct tttttattac ctacgctacc
     3121 tttgaatgag gacacaactt tttttgcctc atccccgatt ttttcaaaat cggtatcgga
     3181 cagaaattct ttgttcccgc ccatatcctc aactaacttt tctgattctg gattgtgcaa
     3241 tccagtatct tccagttttg cttcttcctg cggttttgga tagtgcagtc cattttttac
     3301 cgtactttct ggattgtgca atccaccttt tttacgcttt aacctggccc ggtacaatgc
     3361 catttccagc gctttcggtg ttacggaaaa gctatattca gcatcaagca gttgagcaat
     3421 ctcttgcctc gatacacctt tatccagcca gccctcgatc tcatctaaac gagttcgtac
     3481 tgctgccgaa aggttacgag gttctaactc ggttgccttt ttcataccct ctccttcgtc
     3541 tgcatttgaa tgtacgttaa cccgtttatc ccgtcaacct gactttgtag tttttctgta
     3601 gttttttagt agtctgttgc ttttgtttgt agtctatctg tagttatgtt gtagttttta
     3661 ccacaattca actatctaga tgtgtagttt ttctgtagtc tatttgtagt tgttggtaaa
     3721 aaaactttca tgcaagcatg aaagtggtga atgtgaacgc tttttgagcg atttacttgc
     3781 acgtaacacc ggtttctccc ttaaaaaagg cgtggtatgg tatcccttaa tggccataca
     3841 ccatacgcaa ttacgatttc atcgtaaatg cttgaaaaca aaacaaatta ttctaatttg
     3901 tgttttaatg tgtaatacgc aacgtattac acatgtggtt ctaagccgca tatatgctag
     3961 atttgtatgt attacatctg tattacacaa aggaaaccta tgccatctat cagtttaaga
     4021 gtgaccgaag agcaaaaaat cgaccttgaa taccgttcgg agggcaacgt atcggagtac
     4081 atcaagcaac agctttttgg acaaaaagag agtgccagtg aagtgatcgc ccggcttgat
     4141 aaattgctga aacgttcatc ttcagagcag caagccgccg gacgagatcg atacatcgag
     4201 gcaatgttga ttgaggtgtt attgatactt cgccaggtga gtaaagcaga tgcgcagaaa
     4261 gttgccggtg gtgaaattcg ccggttaggg ctggagccgt ggtcagcaga gctggcccgg
     4321 gagagagagg aacagagtca tgaatgaagc ggataagggc aaaatttgcc tgggggcatt
     4381 gctttttacc ccccttgtta cgtggtttat ctcggcgaaa gccttgtatg gttttacgcc
     4441 aaaagatgcg cgtgaacgtc tggttttact tattcaacag acttttgatt tatggccttt
     4501 atggggtgct ttattagtcg gtgaaattat tgccatcata ggcttaatca tatttttcaa
     4561 atttaatcac cagatattta aaggtgcacc atttaagaaa atatatcgtg gtacgcggct
     4621 tgtttctcag cgggctttag catcaataac taaagaaaga gagccgcaaa taacaatagc
     4681 cgatattcca atccctacaa aagcggaagg tacacatatt tcaatagccg gggcgaccgg
     4741 tgttggtaaa tcaacaatct ttgctgaaat gatgaaatgt tgcttgatgc gtggaaaaaa
     4801 gcaacgtatt gcctcaaata aagaccgcat gataatcctc gatccagatg gcgatttcct
     4861 ttctcgtttt tataaaaaag gcgataagat tttaaatccc tatgatgcca gaacagaagg
     4921 gtgggtattt ttcaacgaaa taaaaagtga ttttgacttt gagcgattcg gtgtttctat
     4981 cgtacctaca gcgaaggatt cgcaaacaga agaatggaat ggatatggtc gtcttttatt
     5041 taccgaggta tcccgtaaag tatttaacac aagtcgaaac ccaacgatgg aagaagtatt
     5101 ctactggaca aatgaagtac cactggaaga acttgaagaa tatgtcagag gcactaaagc
     5161 acaggcttta tttgctggta gcggtcgggc cgttggtagt gctcgctttg tgcttagtaa
     5221 taaacttgcc gctcacctga aaatgccagc agggaacttc tcaattcgtg aatggctgga
     5281 agatccgaaa ggcgggaatc tgtatatcac ctggacagat gaaatgcgtg aagccttgaa
     5341 atcgcttatt tcatgctgga cagatagcat attttctatt gtgttaggta tgagcaaaag
     5401 caactcccgt aaaatctgga cgtttataga cgaactggaa tcccttgatt acctgccatc
     5461 attacgtgat gcgttaacaa aaggtcgtaa aaaaggacta cgggttgtca ccggctatca
     5521 gtcgtattcg caggtcatta gcatctatgg cagtgatgta gctgaaaccc ttctgtctaa
     5581 ccatcgtaca tcggttgtta tggccgctgg tcgcctgggt gaaagaaccc tcgaatttgt
     5641 ctctaaatca ttgggggaga ttgagggcga aagagaaaaa acggggatta gccgccgctt
     5701 tggtcagttg ggaaccaaaa ataccaatga tgatcacaag cgcgagcggg ctgtaacgcc
     5761 aaccgaaatc gccacgctgg atgatctgac cggctacatc gcgtttccag gaaatctgcc
     5821 agtggctaaa tttgagactc atcacgttaa ctacactcgt tctaaccctg taccgggcgt
     5881 ggtcttacgt gaaagcaccg catttgcagg aatgtaaata tgctgaacat tacgacgatt
     5941 acccgccagc gtgtcgataa ggttgttgat tactatgctg atggcgcaga cgattactat
     6001 gcgaaagacg gtaacgcgat gcagtggcaa ggcgctggcg cggaagaact gggcttaacc
     6061 ggtgaggtag aacaaaaacg gtttgcgaaa ttgcttgatg gcaaagtaac ggatgacatt
     6121 tccgtgatgc gtaaaacggc caacagcgaa agcaaagaac gattgggata cgatcttacg
     6181 ttttccgcgc cgaaaggcgt ttcgcttcag gcactggtca acggtgataa acgtatcatt
     6241 gaagcgcacg atcgggcggt cactaaagcc atcgaggaag cggaacggct ggcactaggc
     6301 cgctttaccg tcaataaaaa aacgcacgtt gaaaacacga ataagctgat tgtcggcaag
     6361 tttcgacacg aaacgtcacg cgagctagac ccggatttgc acacccatgc ctttgtaatg
     6421 aacctcacca aaaccagcga tggtaaatgg cgttcgctca cgaatgacgg cattgtgaac
     6481 tcgcttacgt tattgggtaa cgtttacaaa tccgagctgg caagagagct ggagctggcc
     6541 ggttacaacc tgcgttatga tcggaatggt acgtttgatt tggcgcattt cagccaggag
     6601 cagatagccc aattcagcca gcgcagccag cagattgagg cagagttagc aaagaatggt
     6661 ttaagccgtg aaacggccag ccatgagcta aaaaatgcgg ccgcgctgaa aactcgtaaa
     6721 agcaaaggcg aagtagatcg cgatgtactc tatgagggct ggaaaaaccg cgccaaagag
     6781 cttcagattg attttgatag ccgggagtgg aaaggtgcgg ccaacgacga tatagcgcgg
     6841 aatacgcagc cagcggcgct ggaaaagcct atcgagtacc aggctgacaa ggtaatgacc
     6901 tttgccattc gttcacttac cgaacgtcaa tcagtgatta ccgagcggga gctgatggac
     6961 gtggcgatga agcatggcta tggccgctta accctcgatg atattcgggc tgcgagagaa
     7021 cgggccataa catccggcaa cctcatcaaa gaagaagcaa catacgcagc ggccacgacc
     7081 aataaaaaac agcagaacgt agcaatgacc cgcgaacaat gggtaacgga actggtgaaa
     7141 gctggccgca gtaaagatga ggcccgtaaa ctcgtagata agggcatcac aaacgggcgg
     7201 ctggtacagc aaaagccgcg ttttaccaca cagttagctc aacaacgcga acgcaacata
     7261 ctgaagatgg agcgggaagg gcgcggaaag atccagaccc catacactcg cgagtttagc
     7321 gagggctggt tagccagcag aacgttaaaa cccgaacagt taaaagcggt tatgggaatt
     7381 attcatactc ccaaccagtt tatttctgta catgggtttg ccggtactgg caaaagttat
     7441 atgaccaaat cggcagcgga ttttctaaaa gagcagggcg tacacgtcac cagtcttgcc
     7501 ccctacggta gccaggttaa agcgcttcag gctgaagggc tggaatctcg cacactccag
     7561 tctttcctcc gggcctcaga taaaaaaatt ggccccggct cagtagtttt tattgacgaa
     7621 gcaggggtaa tcccggcccg ccagatggag gaaaccatgc gcgtgatccg cgatgcgggc
     7681 gcacgagcgg tattcctggg cgataccaaa cagactaaag ccgtcgaagc gggtaaacct
     7741 ttcgagcagc ttattaaagc cggtatggaa acggcctata tgaaagatat tcagcgccag
     7801 aaagacccgg aattgctgaa agccgcgcta aatgcagcag aagggaaaat aaaggcgtcg
     7861 ttgacccacg taaccagcat cgtagaggaa aaaaatcatg atcagcgcta ccgccgcatt
     7921 gtcggggatt acgtggcaat gccgccgaca gaccgggcta acgccctgat catcaccggc
     7981 acgaacgaca gccggaaaaa aattaatgag tacattcagg ccgagctggg gctaaaaggc
     8041 cagggtatca attacccgct tctgaaccgt cttgatacca ctcaggccca gcggcagcac
     8101 agcaaatatt acgaaaaagg agccgtgatt atcccggaac gggattacag caacgggctg
     8161 aaacgcgggg ccgtttatac cgttctcgat accggccccg gcaataaact tacggtaagc
     8221 gacggcagcg gcgacacaat cgcattttca ccggcgcgat tttccaaatt atccgtgtac
     8281 tccgttgaaa aaacggagct ggccgtgggc gaccaggtaa ggatcacccg taacgatgca
     8341 catctggatt tagcgaacgg cgaccgtttt aaggtaaaaa gcgtccagag tggtgaggta
     8401 ctgctggaga acgagaaagg gcggctggta aaaattgatg ccaacaaacc tatgtactta
     8461 gggctggctt acgcttcgac cgttcatagt gctcaggggc tgacctgcga caaggttttt
     8521 atcaatatgg atacccgatc actcacaacg gccaaagatg tttattacgt ggctgtcacc
     8581 cgcgctaaac acgaagccgt catttacacc gacgatgaga agaagctgga taaagcggcc
     8641 agccgggaag ggttcaaaac cgccgcgctt gagctggaac aactcaaacg ctatgccaaa
     8701 gagcagcagc atgatacccg cgaaaaaggc cgagacaaag ccgagccgac gcaggataaa
     8761 ggtaatgccc ggcctaaaga taaaggccat gaaaaaaata acgatgacag agccttgaga
     8821 ttataggagc gagtaatgac ggtaaggctt tattacaacg ccgccgattc acgcgctaaa
     8881 gcaagcgctg aatggcacga taactggata agtaaaagtg gattgaaagc gcggtactgg
     8941 actgataaag ccatatctga ctttctcgac caaccacaaa aagctggccc cataatggcc
     9001 tggaagcgga aggatgtgct gaaggttgag agcacctctg aatttcagca gtggatggca
     9061 aaacgccgca ggtggcttat cgcgcatgga aaattacttg ctgaagatct cccctcaaag
     9121 tgaccttgct ccccggacta aaccggcaga acaaacccac cccggattat tgggagccgg
     9181 tattgtccgg gggcattatc gtagcatttg tgttgcatac agcccgtaaa aactcattca
     9241 gcgaacttga ataatcggtt gtgtggccac gtcgccggca gcagctggcc aacgctggcg
     9301 tcgaaaacgc gaagttaata aaaacataaa gttatgatgg gatggggtaa gaaaagggca
     9361 ttcaaaaaat tcgatgccct tttgtggaaa cttgcgctat cgcggggaaa aaccttcttc
     9421 agccattgcc ctctgtaatt tatcgacggc atccttgatg acatacgcct cgtcatcatc
     9481 aacggccccc ccccgtaaat cactccacgt caaccgctta acaaactgcg ccagcgccag
     9541 cgcttctttg tcatccagct ctaaagacaa cgtattgata ccttgcccca tcacccacct
     9601 cgttagtctg taaagcggta cgttttctta ccgccctgcg tttcatgaat cagcttaaac
     9661 ccgcttccgg ccagcagtct catcattttt gtggccgggg ggagacagga ggcttccagc
     9721 cggtgtccgg gcgtggcttc gatgattgag gcaagcatac tcttgccaat gcctttaccc
     9781 tgctcatcag ccgcaacagc gaacatacgg atctcaagat gagatgcccg gcccgcaaaa
     9841 tcattgcggc cggttaacag cgaaaatccc accggctgcc gcgttaactt ctcggcaaag
     9901 acaaagagat aatcccctac ggggatatta tctctgtatt gttgggtgac actttgtagc
     9961 tcagatctca ctgtttcaag accgttgccc tcggcataga aaaatgcgcc agatattacc
    10021 ccatcgcgca ccaggttcat gatgaaagga atatcgccgc tgtttcctaa tcgcatatca
    10081 agcatatcgt tctccattca ataagacggg gtaaaatccc ggccctgatt ccagcgtgat
    10141 tgccagtgct tcaggtactg cccggccagt tcgggcgcgt cccacatcac aatcgcgttt
    10201 tcagagttat atttctcggc actggccgtg tagttaaaac tgccagtttc cacatgacgg
    10261 ccatcaacga tgatcacctt gtcatgctgg attttgtagt tactgttaac ccgcagcgga
    10321 atacccgcgt tcgtaacaag attcattgcc gcacgacttg cgcggcccgt attgccattc
    10381 tcatcaacga caattttcac gtctacaccg cggcgtttgg ccgcaatcag cgctttcata
    10441 atatcggggg cagtaaagct gtaggccatc attctgatgt tatcttttgc cgagccgata
    10501 acgttgataa cgagctgctg cgcggttcct tccggcgaga aacctacttg cgccgatgca
    10561 gcaaaaagag acggggccga agccccgtaa agtacggcgg caaccagtgc cgctttaaag
    10621 agaaagttgc gcttttttaa atgctggatc ataaagaacc tcaacaatct ggcgatgttc
    10681 catgtacacc acgacatcta tcgtggtgta cagcgttttc ataatcacgt cataatccag
    10741 cgtctggccg acaccggttt gcttgataag cagcgcaata cggctgaaag tggactttgc
    10801 atcgtcggcg tgggtggatg tgatcccgcc cggatgtccg gtattcagcg agttaatgta
    10861 atcccatgct gcatcatccc taagctctgt catcatgata cggtcgggag aaagacgcat
    10921 acacgctttc aggctgaccg ccggggccag acggccatcc tgatcgccgt acagcatata
    10981 aaccatttcg tgatgcagat cagacccaat ttcgtgaacg tcctctgaaa ctacaatgcg
    11041 ctcggtataa ggtacttccc gaagcaggga gcgggtaaac gttgatttac ccgaaccggt
    11101 agaccctgat acaacgatgt tcagcttgtt gcgtaccgca attttaaaaa acgaaacgag
    11161 gtcgtcttta tcgagcaatt ccagcaattc ttgctcgaat ggctgaaggg ctacttcacc
    11221 ctgaatcttt cgtttccagc cagtgaaacg gccctcatcg cgaagttgtt caagagactt
    11281 atcaactggc agatgcttac gaaacgcgat ggctactgtt ccctccagta cggcaggggg
    11341 taaacaaata atcccccttg agccgtccgg cagaagcacg ttattaacgg actctttcgg
    11401 tagtccgtta taaccacaaa gcgtgtcggt taagcgtgat atatattcag ccgtaatttt
    11461 ctcatcgtcg tggaaaatac ggcctttcga cgtttcacaa acaacctgct gatacttgtt
    11521 aattctcagc tcccacacat cgggatcact caggtagcgc tgaagtggtt cgagcgtcag
    11581 ccataccccc tgctcacggc gggggcgttg gcgaatatct tgaatattac tggttaactc
    11641 agtcattcat ttctaaccca tatacagtgc tgaaatccag atcgcgggct acgtagatgg
    11701 atacggcatc gccctgcgca gcgtagagcg ttggcgggat attaatcttc gcccgtaatg
    11761 cctcagtagc aagctggtcg gtactgtttt ccgttgtgtt aaacgtcaca tcggagttgt
    11821 tgttgttaat cgacgcgata ccggctttca tgccatcagt cagcacagag aagaaaatgg
    11881 catcgcccat tcgttcccaa aagtgagagt tgacctgacc aggtacgccc gcactaccta
    11941 aagcgttagt gccgctgctg tcgaggttaa caatggtctg atccggatta cgcaagcgtg
    12001 accagagaac gaacacacga ttctggccgt tctggatacc gctattctgc tcgccagtga
    12061 ccacagcccc tttatcaatc agttttacag taccgtcagc agagtacaca tcacggctta
    12121 cagtacattt cacctggccc ggaacggtgg tatccagctc agtatttgta ccgcaaggaa
    12181 tcattgttcc ctgcgcaatg gtcagatttg gatgtggcat tacagatgcc tgagcgacag
    12241 ccatacgcgc cggtttcatt cggctcgcca gtgcctggct gtttgaactg gtttctgtat
    12301 tgtcctgacc tgaccggcgc tcctgttctt tcgcagtcgt agcctgtttc tcaggatcga
    12361 caccgttgaa ggacacacct agccgggcgc gcataatttt ttcttccggt gttagctcct
    12421 ttttctgatt atttaacgtt tgccgggcaa cctgctgctg cggctcctgc gtcgtctgca
    12481 acggaggaac gacgctattt ttcggcgtat tgtcaatggt tggcggcaca tcatcaaatg
    12541 actggcgcgg taaggagctg gtcataacct gctctttacc ctttttggga tcgtcggcca
    12601 gcttcttaac gtgcatctgg ttatagatga accatcccac cattgctgaa cctatcaaca
    12661 ccatcagccc gacaaaggcc cgcgcaccgg caatacgttt tttaggggaa ccgctgaagc
    12721 cctgacgctc atcctcgatg ctggtatctt cttcatcgag gtaatctaaa ttttcctctc
    12781 tgtcttttct catgatttat ccccctcacc ctttttcacg cgcttaacgt ctggtgacgt
    12841 agtgccggta ctgatcgccc caagatttgg gttgtaattc atattcagga cacccacgac
    12901 tttatttccg taacgaatac gccattcttt tgctaccgtt tcagccacaa caatgttgtt
    12961 atattccccg gctggatgct ggttaacggt atgctcttta ccatcatcac cgatatagaa
    13021 aacaacgggt aaatctgcgt ttgcagggaa tttgaagtaa gtaaaacgga aattatccca
    13081 aacgtttacc ggggccaaag tccgatattc atcttcatct gacattttat agagtaggtt
    13141 gtaaggccca ttctgaaggt cttttaacgc ctttttcacg cggttacttt ccagcgtttt
    13201 attagccttt ttcatatcct caaatggata gaggtaagta agctggagag tggcattttt
    13261 catgctccag ggcgtcttga taaagttggc tttaacgtta ccctgggcgt ctttcgtggt
    13321 gtagtcacct acatagtgca gcactatgtt ataggtgcgc ttgttcgtga ccagtacaag
    13381 gttagtatcg ctgggaactt cccctttcgg tttgataaat atgttgtttt caacatgggt
    13441 aaacgcataa ctattactgt caccaaaagc gtgtgtcaca tagctttcat cgggcgcaac
    13501 cacgatatga gttgcaacac cggcaacgga atcaatacgc accacgtcaa ccgggttata
    13561 caccacggat ttaatacggt agtcgtatgg gctacctttt cccacttcca gcgccagcgc
    13621 ctgaccagag aggccgaggc tgaccagaat taaaccggcg attaattgtt ttttcatgat
    13681 cagcctccca ctgcgccaac gttctcagcg ttcttacggt aactcgttac acggaagcca
    13741 agcgggttga tatagcgctg ctgcgcggtc attggtaacg ctttgtactc atacgcaatc
    13801 gttgcaatcc agtagcgcgg cggctcaggg ttcggacgct ggcgaatgcg ctgctgcgtg
    13861 gtaaagcgaa cggtggcaac accgtgttcg cggtcggtga tcaccgagtt gatatgaacg
    13921 gtcgttcttt cagagtcacc caaccgctta tcaatgcggt tcgggccttt gaacatggag
    13981 agatattcat cggctacatc gccggaagcc atcaggctca tggcgtcata atcaacctga
    14041 atactgttgt agtcgtagga ctcacggtga ataacaaatt gtgaaatcca atactggtct
    14101 atcacgtcgc cataagtcgc ttcatcgcgg gtaattttca cctgcgatac ttcgcctgta
    14161 tctttgttaa tcgtggtgag gtatgccggt aacggctgcg caaaacggat aatgacgccg
    14221 accgcagtaa tcatgctcac aacggcaaag acgaaaaagg ccgtggcaat tttccaggcg
    14281 cgagagcggg aattaaggat ctcattaacc atatcgcgct caagcccttg agtttcctca
    14341 tggtacttat tcagatcttc ccgcgatatc gcttgatgtt tgtttttctt cagcattgtt
    14401 actctccgtt gttagcggca tctgcacgat acagctcggc gggatacgtc ttattaacat
    14461 caaccagctt tttcatgttg ggttctggcg gcggcgtcgg gctactggaa caggcggcca
    14521 acagcagccc gataagtgcc attgccgtgt atttgaagaa atgcaccatc tttgtcactc
    14581 cctttgaatc aatcacaaaa aaataataag tcatcaaaat tacaatttca atgacttatt
    14641 aaaaattaat ttctactcta cttttagcgc cgtgaaccct ttgcgaaacc ctgcatttgg
    14701 gaacccgcag cggtggccgc tcccgcgccg gggccaccgg cagccgtagc cgccgcagtc
    14761 ttagcgccag taccgccccc ggcacctgta gcgccttttt gaccaccagg ctgatagcca
    14821 ccaccgccag ctccacggcc accgccaccg gcgttaggta tcagctcctg aatacccgca
    14881 gagataccat ccccccaacg ggaggctact tcaggaatgc gcatcaggat caggtaagag
    14941 acaatcatta tcagcagaca agcaaaaacc ggccctaaca ggctactgtc agccccggaa
    15001 gcggtgacgg catcgagcgc tttttgatag aacttaatca tcaggccaaa tagcatcgac
    15061 agcagaattg ttaccagccc atagttaacc atcgagccaa gccatttatt gaacatgcca
    15121 tacagcggct tgaacaacag gcagaagatg aagataggcc caaagcacac agtgattgcc
    15181 agcagtaact tcgccatcag taccagcccg gccccgatac cacagatcaa caccgtggaa
    15241 ataatgaccg cgcaagccag gaataatgac gccagcccgg aaccgctata aatatcggcg
    15301 ttatcaaacg cagtacgcgc aacctgcatc ccgtcatgta tggccttgtc gatgttgtta
    15361 cccattgcat cttcagtgcc accggacgaa ccgttaataa ccagtaccga ggaaaactca
    15421 tccgggatct tcatggccgc atcagccagt tgggtttgat acagcccgcc cgcgctggca
    15481 aagctgatta tcatcgacca cacaatgaat ttttttatca acgatgagag cggctcaccg
    15541 tgtggccggg ctaatgtaaa cagcccgtcc agggtgagtt tgcaaatcaa cgccaaccca
    15601 attaccggtg aaatggtgga tataacaact ccgagattag aggccacaaa ttcctttgtg
    15661 accgtatcca tgtaattgaa aatatccgtt gtaaatgaaa aggccatgct ttccccctac
    15721 cctaatcagg gcgtgacttt tggcattgag aggccatcat catttttgcc aaacactttc
    15781 aaatctttct ctgcttccag cgcgttctga caatccggct tcactttgag cgccgcatca
    15841 tcacggcatt tttccaccat cgctttacgc tcctgatcgt gttccttgta ccaggaaaca
    15901 ggatgttcag aatcacaacc ggccagcagg aaaagagcta aaggtaaaat cagttttttc
    15961 atggtttatt ccgttacgtt aggcatggaa agatcttcac cgtcagcgcc gaggacaaag
    16021 cgcttctggg cgtattgttt ttgttcctgc aaaatcttgt cttgcgaggt ttgcagcatc
    16081 gccatcagtt gcagcttcgt ttgctccccc tgaatagcac cttgcgcggt ctggatacgc
    16141 gcctgaaggt cagcgatttg tttcatgtct gtggttgaat caatctgatt ggtcagctcc
    16201 tgaatgttat tcagctccgc catttcattg ttgtaagcgt tctgcgccat cacacggtca
    16261 tacgcccctt tctccgccaa cttctgctta atgaaactca tcgcttcgga acggttcata
    16321 ccgtcaatct gcgactgaaa ttccttcagc atggattgag cagatgaagt gatacctgaa
    16381 ctgctgttca tggcgtcgct gtatacctgc gtccagtcag acggtaaatt gcctttcagc
    16441 gtactaatat cgtcattcag caaattaccg ataccagaac tgccggttaa ggaagccagc
    16501 gtttgctcct gcttcagcaa ttgagatttg agctgttcaa tttgctgcgt cattaatgtg
    16561 acctgctcaa gcgcctgggc cagatttgca ggatcgttaa ctaccagttg cgcattaact
    16621 gcaaccggcg aaatagccag agctaaaaca aggcttgcaa gtgtcttttt catgtcgtta
    16681 cctcacgctg cgagtacaga tttccagtag ggttcgagcc atttatcagg gttatcatcc
    16741 ccaatttgct caataatttt cgccagtgtt tcggcgtttt gggtttcccc tgacaggatg
    16801 ctaaggatct tatccagctt cctgaagttc tccggcgtct taacgcgcgg ggccaggttg
    16861 aattgcgcca tcgcgctttg gctgccttgt ttcaccagga actggcggga gttctcagga
    16921 atagacagca gcgcgtcaaa ctctgccggt gtcaatttga ggcgagtaac gtagtcctca
    16981 taatccgcat ccgggttttc cagaagaatt ttcgttacgc actgctgcat gatggtttta
    17041 ccgatggagc tatccagcgc atcgttcggc tcttgcgtgg agaatacgta aaccgcatct
    17101 ttcttacggt ctgttttaag gccacgtttg acctccacac tcataattgg atcgtcaagg
    17161 tactggtgaa actcatcgaa tacctgaatc acacggcgac ggccatcaat agactgacgc
    17221 acacggaaat tgagatacat caggagcgga gtacgtgttg caggggggat ctcattatct
    17281 gcaacaatga aatctgtcag gtcaaagccg taaatatcgt attcaccaag attcagtgaa
    17341 tctgaatcgt tatcgaacaa ccaaccgttt tcatggccgc gagtccacgg aacaagcaat
    17401 gacgccagtg tttgtttact gcccgctgtt tgatatggat tcggcatctg ctgaattaac
    17461 atatccacgg tgcgtaaatc tgtcggaatg agggagttct catccatcaa agcatcgacg
    17521 gcgcggttaa ggtcattaac ctgatcagca tcgagtacgc tgcctttggt aatttcagcg
    17581 cacaggcgca tcaggcgctt acaaaatgca atgttaactt tggtgccagg catctgtaga
    17641 ggtgcccacc cggaagcaac gccctctttc agaaccgtgt agtgaccgtg taacgcttta
    17701 atcatcggca tcatgccctg atcgcggtca aaggcaaaaa tgcgcgggtt atacttcatc
    17761 gcttgcgtca gcaggaagtt aagcagcgta gttttacctg cccccgaacg cccaagcatt
    17821 aacgtatgcg ccagcggtcg cttaccgaaa gacatttcat cttctggcgt tacatgcaag
    17881 ttcatataca gcggcgtatt tgccaccgtt ttgaacagcg tcagcgctgg cccccacggg
    17941 ttattatttg ctttcccgga cataaaatta tggaaggggg agaagcaaag aaaattccag
    18001 ctattcagcg ggcaaggtcg tggcgacagg tgttgattag ccggaagttt tgcataatat
    18061 gccgcttctg aagctaaccc tacctggctg gcaatcagcc cgcagttgtt cagcatattt
    18121 ctggcaacac cggcgtttga acgggcctct ttaagcgtct tgccaaaggt gtgtaccgta
    18181 aggtgatgcc agcccatgat aaaggtacgt gaaacaacgc catcaacggc gtcactcatc
    18241 tggtttatct gcgtaaagga tggatcgcct gtttccagca gagctttttg ttggttagtg
    18301 aggtaagttc ttgccgcttg ctgggacata cagcaatacg tttgcgttaa cacaaactca
    18361 aacggtgctt ccatcaggat attgatctga ccaggctcag tatcggaatc gtaatcccgg
    18421 atttcaacgg cagacgtata gcggcgttcg tcagtaccgc gaatctcgat accatccccc
    18481 caaaatgaag atattgggcg ggtagtagcc aaatattcac ggattcggcc acgacaaacc
    18541 ggcactggtg cccactcacc attaacgagg taatagagcc actccagcgc tttagaatag
    18601 gtgtgttgag taccactaaa gacttcttta tcttcctgaa cgtcctgata ttccacatcg
    18661 gccagcaaat cttcacgcag atcgataatg tcctcatcat cttctgcatc atcctttttc
    18721 tgctcaggaa tgacattccc ccgtttgtcg cggaagtagt agcctaaacg gtcaatgcca
    18781 taaggacgca gcgagttcat gacctgttca caaatatctt ccagcgcacc aatagcatca
    18841 gcctgcattt cgcgcagctc gctagccgat ggcttatcaa actttgccag catcttttga
    18901 gcggcatccc caacagggtt ataaacaacc gtcaggtaca ggtcatttac catcattggg
    18961 gtatcatcaa actgatcacg ataatattca ttcaccatgc gtgggaacgt catattgtaa
    19021 tgcgtgtcag gataattatt aatttcgcgg tggtgtaagt gagtccataa ttttacatgc
    19081 tcactaccaa tcccttttaa aagctgattc aaatccgcat gccacttaat tagctcggca
    19141 tcagaagcac agtcatgggt tcgcccacgg attttaaata tagaaaggta ttccccattt
    19201 accgtactga taacatgggg cgtgacatgg taggagtaag gaatatattt caaagaggaa
    19261 ggttcttttt tgaaatcttt cacccccctt tttttcattt ccgctacggc cattattttt
    19321 tatctccata atcagtaggt gagtaactag agccgcccca cagtttagta aatggggagt
    19381 taatcatatt tagccctttc gtcatgatag ccagccatat aatacgaaac atgcggtcat
    19441 catgcttgct gatacaaaac tcaataaacc acagcaagcc aaaaagaact aaggcccaaa
    19501 ggtggatcgt cataaataac gtcgcacaaa atatgaaggt ggcaataatt actgttcgcg
    19561 gaacaccggc aaatgtcggc agtcgcgtag cgcctttaaa taacggatat ttaccggata
    19621 aattcatcgt ttcctcccgt cagatacggg ccgggggata accccccggc gaactttctt
    19681 aactcagccc gaacaggcca acaagataag acgcggaacc gacaacaatc agaccgacaa
    19741 caatacgaac cgcccagctc gccgggagca tatgagcgat ccatgcgata gcactcacga
    19801 tgataagaac agtggccgca accggaatcc acgtcattaa ccaggagtta acggaattca
    19861 tggatgattc accggtatct gcaccggcgg ccagcgccag ctcaggaaca cacagagcaa
    19921 ccatcatgaa cattgccacc gggaaaaaac gtttaatcgc tgtattcatc tttttctaac
    19981 actccatcat caggaaaaat aaaatcaggc tcatccagga aaagccccac ttctcttgca
    20041 ttaaaatcgt ctctcagcat gtcggccagt atccgcagat cggcccacgt tctaaccccc
    20101 tctccagact gaactcgcag agagcaagtg attacgcccc cttcactatt tttcacatca
    20161 aaaagcggta tccatttctt tttatccatc cgttgaattg cgatccgaac aactttgttt
    20221 tgattgaata cttcttctaa ctgcttcaac aaaatgagat aaacgcgcat ctaaactgac
    20281 tcctgttact ccctacttct gccggaaagc gtcaccatca gatgcaccaa aagcgtcttt
    20341 atccgagcca ccaaaggcat cagtcatacc ggcgtctttt ggtttttctt caccatcagc
    20401 agcatctacc ggcacagcat ctatagctgt atcaacactt ttcacatcag tggagccatc
    20461 atcggctttc aaagcaggga ttacgggttt tgattgccca atttgagcaa ccacctttga
    20521 tacataaccg tttgtaaatc cggcggttag tgaacccgta ttataacaag ataaagcgtg
    20581 tctcaacgct gactgccccg gcgcatattc ttttgttgcg agctggtagc aataattaag
    20641 aacgtattga gcagcttcga gatttttaca accattaaac aaatctgcgg cagaaacatt
    20701 caattttggg aaattcgcag agttgatttg ccctaaacct acgtcaaagt tataaccatg
    20761 agccgttagc cattttgtcg ttttaacagc ttcatctagg gtacgcggct gtctggctaa
    20821 cggtgatttt gttcctttag gaacgttgac gtttatcgcg tatgggttgt tgcgcgattc
    20881 atggctaacc aggtacccaa tagttaaagg atgcacttct ggcgcacaac gttttgccag
    20941 agccataacc ggcgctgaca gttccgcatt tgcggatgtg gcatccaaaa gaccagcaat
    21001 caacagtggg aaaagggcaa caacctgctt catctctttt ttccttgaaa ttgcaatttc
    21061 aatgattaac tagtatagta aaggtaaatt cgaacatgtc aagacaagat gaaaagaagc
    21121 acaaaacaga gcaggagcgc gaaacatcag tgcctaaaag aaaaatcata ttcgtaccct
    21181 tgcagtcaga aaaaagtccc aaaggggagc ctcgctaccg agatccagcc aatccattta
    21241 acacatgggt tgggagagga aagcgccctg actggctaaa aaaatatctt gatgaaggcc
    21301 gcgagctttc ggagtttgag atcggataat aaggagctga cggatgagta aaattattga
    21361 tttccctacc ggaaaaaaga gggagagaag ggctaaagct atccgagcgc aacgtgataa
    21421 agaagcgatg cagcggagca aaattgctac ctcccaattt tggtgggcta ataaaataaa
    21481 gttactcacc gttattaaac agtcggtgcg atttctctta atatatttag ggttattagc
    21541 taccgacata tttatctatc tcgtatttat tctaggaaaa ctcctaaaat tctttgcgat
    21601 gactggtatc atcgctgcgc ttttatttct ggttatggaa tataggaatg gttggcatta
    21661 tacgcaatca atattccatg ccgcagcaat atttttcggc ctaatcgccc tgcgtatcgg
    21721 gcatgacaaa ctactgaatg gcctaataag gcttaaatcc tatctatcca gaaaagggtg
    21781 ataacaatgc ggaagataat aatagcgtca gtggtgatac tggcatcgtc ttactccata
    21841 gccagttatg caaaagatcc ctgcaaaacg ctcgcttgca tggcagcaaa atctggcggg
    21901 gaatttggca gcgtgggcga cagtgattgc tccggggcga tagctgactt tttcaatatt
    21961 gtaaagaaga acaaacacgg tttccgccca ggcaaaacat ctgacgctcg taaacagttc
    22021 ctgatggaat gctccggcgc tcaagaaaat acagccgctg taaacagagt tatatctatg
    22081 ttcggacgtg taaaaggtta atttatgaag attaaaagca ttctctttac gacagttctc
    22141 ttattatcag gatgcgctag tcagtcgcag gtagagcaat tatcaaagca ggttaatacg
    22201 ctaaaaacag acctgtacaa tctgcaaatc cagcagcgca atgatacaca ggcacttcag
    22261 cgagaagtac agaaatcgcg tcccatcggg gtttgctatc ttgacggcca cccctactca
    22321 caaggagcgg ttattgctgg ccgcatttgt gccagcaatg gcgttatcgt caatggcaaa
    22381 cctacagaag tttcatggca ggtttatcac cgccgctaac aacgcgcgtt cggggcttcg
    22441 gccccgtttt ttatggtaca ggtagcatgg atatactttc ccttttccct cctaacgtaa
    22501 tcgcattgtg ggccgtgtca tttggttttc tggccgtcct gtattggtgg aagatcaccg
    22561 ccagaaaacg cagacacaaa cgcaagcaac aacaagcccg gcgtgtgctc gcaaaaattc
    22621 agaccctacc ggcgttcggc tacaagatcg cgtatctcag gaagatagac cctttcacct
    22681 ttgaggaact gttactggag gggtttgagt cgcatggctt cagaactatc agaaataaac
    22741 gctataccgg tgatggaggc attgacggac aggtaataat cggaaaacat cgttatctca
    22801 tccaggccaa acgctatcgc ggccatattg ctttacagca cgttcaggag ttcgatacgt
    22861 tgcttaaacg acataactgt cgcggtttgt tttgccatac cggaaaaact ggcgcagctt
    22921 caaaagctgt tagcttcgcc agtgatcgga tggagattat cagcggccag cgcctaattg
    22981 atttgctcac gcccggcagc tccttcacca tcgcaaccgc accgcagaca atgatgaggc
    23041 gtaccgcagc aacgcgagga acgaacatca ttgtcgagga agcggataaa gaaacttaag
    23101 tgatgtgaac aggcccgaaa accgggccat cgttactctc catagatttt aattcctacc
    23161 caatcaatac ttttaatttg gagcgaacct cagctaaaac agcggcagac acttttcctt
    23221 tcttaaccgc cccccgtttt cgccaatcaa ggcttttcac ctggtcagcg agtacagcgc
    23281 tcccctctcc gttccgcacc tcgaatggat aaccttttat ttttgttgtc atagggcagc
    23341 acaacaacag tcctattctg ccgttatata ccgcaggact tagcactaaa gctggcctat
    23401 ggcccgcttg ttcatgtccg gcttgcggat taaaatctat ccatacaata tcaccggcat
    23461 caggaatata atcacgcttc attttttaat ctcttactta tatacccaac ccatataaat
    23521 gtaattatga gcaccccaca aaaaataaac ataattgcaa acggagttgt atcgagcaga
    23581 gatacagcct caacaccacc aatagagatt gagttatctt taaataattt accaaaccct
    23641 aaccagatgg aatataaccc aacaccaacc caaataagag cacctaaaaa ctccagatag
    23701 ctataaattt ttttcaaaaa attcagcata ttccctccgc agcagtaaag atcttacaac
    23761 taaggctgcc ccatcgaata aaggatctat cctctttttt cattacaaca actccttccc
    23821 aacaggagcg ccgaaagata tttcctcatg aatattttcg ttagtaacac cggccatcag
    23881 agcatccagt gaatattcct tcgttttaac gggcacgata gtaattgcgc cgtcctctac
    23941 tgacagctcc actacatcat caacgtttaa cgaagcggct ttcacaatcg cagaaggaag
    24001 gcgaacagat agactattcc cccatttttt aattattact tgagtcatga catacctctc
    24061 aataaacaaa gaaaactaat tagcgactct tcaggatgta ccaggcttct ttcgctgctg
    24121 aaagcgccca aacccacgcc agagtcgatg cgatacacat tgcggtcata ttcccaaagt
    24181 gtcccggcgt gtattcatgg ccgtgtaaaa caagcccaac caaagaagcc acactcatca
    24241 ctatgaaaac aatcccaaac atgatgtgaa acataaggcc aaacactcat tacctcttgt
    24301 atcattattg ttgatacaac cagtgtagag ccaccccctt taacgtgtca acattgttga
    24361 tacagaaagt gtctcacaaa cgatgatttt tgttacactg cccccaccct atccaaaaat
    24421 ataaaaatgg atgctgtcag tgtaacaaaa ctcgttacaa tatcatgtgt aacaaaaacg
    24481 gtgtaacaaa agcaggacat atgaaaatag gctacgccag aaagtcaacc aaagagcagg
    24541 acacatccct tgagtatcaa atcgaggctt tacaaaaagc tggctgcgaa aaatggtatg
    24601 cagagcaggt atcgaggggc ggtaataagc gcctgaaaac aggtacacca gagttggaaa
    24661 actgtctgaa agcgcttcgc gccggtgaca ccctggtagt atgggcgcta gatcgattag
    24721 gtggcactct cttgcagctc ttgcagctca tgaatgagct acgcagtaaa ggtattcact
    24781 ttgagagcct caaagagcgc atagacacac aaagcccaat gggtgaaatg tactattccc
    24841 tcatcgctat tttttccaat ttcgaggtag ccagaaacca cgaaaggaca atggccgggc
    24901 ttgcagccgc aaagaagaaa ggacgcattg gaggcagaaa accaaagcta tctccacagg
    24961 acattaaaga aattaacgcg cttgttaaat cgccagaaat tacagtaaaa gaaatcgcgg
    25021 cccgttttaa agtttctcga cctacgattt atagacatat ttcatccgat atacaggatg
    25081 aataattgac cgggcgctgc cggtgtggga accaccccat gttcgccggg cgctgccggt
    25141 atgggaatca ccccatgttc gccgggcgct gccggtatgg gaatcacccc atgtttgccg
    25201 ggcgctgccg gtatgggaat caccccatgt ttgccgggcg ctgccggtat gggaatcacc
    25261 ccatgttcgc cgggcgctgc cggtatggga atcaccccat gtttgccggg cgctgccggt
    25321 gtgggaatca ccccatgttt gccgggcgct gccggtgtgg gaatcacccc atgtttgccg
    25381 ggcgctgccg gtgtgggaat tcaccccatg tttgccgggc gctgccgatg tgggagaatc
    25441 accccatgtt tgccaggcgc tgccggtgta gaatcaccat gtttgccggg cgctgccggt
    25501 ggccaggaat accccatgtt gccgggcgct gccggtgtag gaaccaccat gttcgccggg
    25561 cgctgccggt gtgaatcacc ccatgtttgc cgggcgctgc cggtgtgaat tacccatgtt
    25621 tgccgggcgc tgccagtgtg ggaaccaccc atgttcatcc gggcgctgcc ggtgggaatc
    25681 acccccgcat gttcgccagg cgctgccagt ctgtgagaat caccccatgt ttgccgggcg
    25741 ctgccggtgt ggaattaccc catgtgtttg ccgggcgctg ccggtgtagg aaccacccca
    25801 tgttcgccgg gcgctgccga catgggaatc accccatgtt tgccgggcgc tgccggtgga
    25861 accaccatgt tcgccggagc gctgccggtg taggaatcac ccatgtttgc cgggcgctgc
    25921 cggtgtaggg aattacccat gtttgccggg cgctgccggt gtgagaacca ccccatgttc
    25981 gccgggcgct gccggtatgg gaatcacccc atgttcgccg ggcgctgccg gtgtcaggaa
    26041 tcaccatgtt tgccaggcac tgccggtgta ggaattaccc catgtttgcc gggcgctgcc
    26101 ggtgtaggaa ccacccatgt tcgccaggcg ctgccggtat aggaatcacc ccatgttcgc
    26161 caggcttccg tatgcgaatc acccatgttt gcgggtgctg ccggtatggg gaatcaccca
    26221 tgttcgccgg gtgctgccgg tagctgggaa tcacccatgt tcgcaggcgc tgccggtgtc
    26281 agctcataca gctatgcagc taatggcttt gatgatgaca ctgaatataa atttaccatt
    26341 actatcaata gagtaagatg cttttaaggg agtttttcat tgatttgttt ttagcgctgg
    26401 atctaaaaag atcgtttcaa ttcggctaaa ttttctgttg agactcaggt agcacgaacc
    26461 gctcattgag ccaaagcatg attagttatc caagcccagt tgatttgaac tgacagaggc
    26521 tttcgtagga gtcttattgt gcgcggattt cgtagacttc cacaatcatg caatgaataa
    26581 gtggtgaacg gctggtaagt ccataaatgt acagagtaac atgatttaaa ctctattccc
    26641 ataccccttg ctttgaacag tttgccaact tccagtaagc gaggtctggc aacacaatca
    26701 tcgaccttct tttgggtaaa aaaacgactg aagaacggct taattcaatt attccatcgc
    26761 acatctttga cagccgattc cgtgtctgaa aactgatttg catgttcagc agcagatgct
    26821 gaatacagca tcccaatggc ccatccaggt ttatcgctat catcagtgga tgaagcggtg
    26881 aagtaagttg cataagacac agcctacaga atgcgcttgg ccttcaagag agataatatg
    26941 cggcttcagt caattcgtta gcctgtttta cattaacctt tttattcaat atcttatcca
    27001 tgttatccac attttatggg tgatttttat accccaatac cacgtttagg gatcttgtaa
    27061 attattttca aaatcacatg aaaggtgggc tgattcccca taagaaggtg ggctgattcc
    27121 cataagaagg tgggctgatt ccataaggtg ggctgattcc catagaaggt gggctgattc
    27181 ccatagaagg tattatttat ttataaaaat caatgtatta catagtggta aaggttatta
    27241 aaaagaaaaa aaattatata taaaaattta ttaaaaataa ccacagggat aactatctac
    27301 tcaacaaata ggcgtcattg ctatctgtca taaactcaca tttgcgcttc ctcgcttttg
    27361 ctgttcgttc ctcgcgttgc tgcggtacgc ctcagcaaaa gactgcggca acgctgcgat
    27421 ctcttaggta agcgattagg tttgatgcag gggggataaa aagaatgagg cccatcaccg
    27481 gcaaatgtgg gcctctggca cctccctgcg aaggaacaga ttagacgttg tagaagtata
    27541 gacagaaagc agcgtgatat tgaaaggatt catagcgcct tatatttaac ctcaatattt
    27601 aaattttggt gaattatgaa gaaatctcta ttcagtatca tcctgctggc actaccacat
    27661 gcaaaggcag cgcgccgaac cttacatgag tgatctttgg gctatggtca gttaattacg
    27721 ttacctgcgg ctgtcacaca ggctgaccgg tgaaaggtat gtcaggtgaa aatcacagca
    27781 ccggcaatcc tcgcatggaa aacagcagaa cccggtctgg atggaaaaat acgccaaccc
    27841 cacttgcagc cgcgttcatc ggtgctgatg gtgttatcag agtattcagg atatgcagcc
    27901 ttagcgacac agcgcattca catcactaca tccacgatag caatcatcga gatgagaacg
    27961 gaaaaattta aacagttcag gctatccaaa ggagacaaat catatcagcc aatgtttccc
    28021 ctcaaataac gcctcacagc cccataagag ctgcttcaac aaagaaaaac taactcaggg
    28081 tatggcccga accaagataa cctcttacag agccattcag ccaatatcac gccagtaatc
    28141 cagttgtcat cgtgcctgta ggggcgctgg ccgctgcgca tgcatcctaa cacccggata
    28201 aatcacgccc ggccgtcgct gcgcgccagc ccgcccgctc aaccgggccg ttgtgaccag
    28261 gagccactgt tccggcggtg tatcgtctga cagcccgcca aaaccggcac agggagggtg
    28321 ggcgcttcgc cacggtcggc gtcaccggcg acatgtgccc tgcccgttcg gctcgggaaa
    28381 tgggcgcgtc gcccagctcg atgtaaggta acggtgacca cgccgccggg cggaatcagc
    28441 gcagttgcct ttcatttatc agccagcagt tcaaggaatt taagtatctt tcgtactata
    28501 taatgatact aaaagttgac ttttaagagg gaaaacctat actttattta cggttagcaa
    28561 tggtgctgag ccggcccgga atttccaacg gcggcaaccg ctccgggaaa actgcgaagg
    28621 ggtgaaaaat gaaattaacc acgctgctga aaaaacattt tgatattgag gaaattaccg
    28681 atgtggatag caccgtaaac cgggaggtgt ataccatttg ggtttatgaa aaaggcgaag
    28741 attgcgagcc gctattaatt ctcaaagatg cacaggattt tatgggtgtg gatggctggc
    28801 ttgtcgggaa tatctattcc acgttgcaac atggcttatt gctacagcat gaagaactga
    28861 aaacgatgat ccgaaacggc gagattaaga gccgttaaat ctatacgcgg tcggcaatag
    28921 tgccgcccgg cccggacaca gcggcggcaa ccgctccggg taaactgcga aggtacagag
    28981 gctactatgt cagtaaaaga tttcacccct accctggaaa ttaaattcca tcgtcgccgc
    29041 tggcgtatca tggtcgggcg ttcaagcctg gcctctttcc gctccgaaca ggacgcaatt
    29101 gatgctctca ataaacgccg ctcattctat gagtattggg ccggttctgc cggtgtacag
    29161 gcagagaaca cagagccggt gattgtccac gtaacatatt gagtaccaac aaagcccgga
    29221 aaccgggctt ttttcatatc gtagagtaca ataaaagtaa aataaaatga tacttttagt
    29281 tgacttatgg gaggggaaaa cctatactgt attcatcggt tagcaatggt gctgaccggc
    29341 ccggaaccag cggcggcaac cgctccgggt aaatagcgaa ggagtatgat tatgttatct
    29401 agccgttttc gttctgcaaa tattctgcgt tctgaccgcc ctcttaacga tgatcagatc
    29461 atgcgttatg ccccgtctat ctttgccact gaagcgcatg aaagccgctc cgaccgttac
    29521 gcctacattg cgaccagcga agtattaaat ggtctgcgtg ataacggttt tcatccattc
    29581 atggtttgcc agactcgcgt tcgtaacctg gataaacgcg aacacaccaa gcacatgatc
    29641 cgtctgcgtc atgccgggca aattaacggc actgaagcga aggaaatcat cctgcttaac
    29701 tctcatgatg gcagcagcag ctatcaaatg ctggccggtg tattccgttt cgtctgccat
    29761 aacggtttag tctgcggtga taccgttgct gatattcgta tcccgcacaa aggcaacgtt
    29821 accgagcgtg ttattgaggg cgcttttgaa gtgctggatc agttcgataa cgttgaaaac
    29881 catatggatg ctatgaagtc tgtcacactg aatgcgctgg aaaagcgtat tttcgctgac
    29941 gcggcgttag cactgcgtta tgacgagaaa gacggccccg caccaatcgc cgcgagccag
    30001 ctccttgagg cgcgtcgttt cgaagatcgc aaagatgatt tgtggacgac gtttaaccgc
    30061 gtacaggaaa acatcatccg tggcggtttg agtgccagaa ctaagcaggg caaatcaacc
    30121 cgtacccgcg ccgttaccgg aatggataag gatacttctt taaaccgcgc tttatggatt
    30181 ctcagcgagc gcatgaatga actcaaagcc gcttaatggc aaacgccccg cttgatcgcg
    30241 gggcttttat caacccgaaa aaggtgatta tcatggcttc aagaggtgtt aacaaagtaa
    30301 ttctggtcgg caatttaggc caagatcctg aagtgcgtta tatgccgaac ggcggcgcgg
    30361 ttgccaatat tacgttagcc acgtctgaaa gctggcgtga caagcaaacc ggcgagatga
    30421 aagagcagac tgaatggcat cgcgtagtat tattcggcaa gctggccgaa gtcgccgttg
    30481 aatatctgcg taaaggctcg caggtgtaca ttgaaggcca gctcagaact cgtaaatgga
    30541 ctgatcaagc gggcgttgag aagtacacca cagaggttgt ggttaacgtc ggcggtacta
    30601 tgcagatgtt aggcgggcgc tcacaaaacg cttctcagac tggtaatcag ccgcaagggg
    30661 gccagcagtt cagcggccag ccacaaacca ccggcacagc ggcaggaaac gaatcgcctc
    30721 cgttcgacgc tgatataccg ttctgaatga tgtaattatt tgtaatgact taataaatcg
    30781 gcccgtaacc gggccgtaat gaggtaaaaa atggcagtag aacgcatttc ccctgaagaa
    30841 tggcagcgta ttgcaccggc attacgcaca tgcagccagg taacgatcga tatggcatac
    30901 gccgtactgg ttgacggtcg caaacaagtc gatgtggcta aagagttcga ccgatcaaag
    30961 caaacggtca atgctgcaat caggcgcgtt actgcgattt ttaacgaagt tatcccggaa
    31021 gatgagcagt tagaatttgt gcaagtctgg ttgccgccag agctggcgaa gcaggttaaa
    31081 gaaatggcta aaccatatca gaataaaaat taaaaggagt tatataaatg gcaaaagtta
    31141 gatttgaaaa ctcacttaat aagatgattt ttgaaattcg tggttatgaa tcattttccg
    31201 aaatggaaac agcattacta gatttttgtg atgaaactat gggggcaaac catcctgata
    31261 tagtggtgga atatccggtt tattataagc attttattaa tgataaaatt tcatatgagc
    31321 atataggtta tgtgaattta ggaatagatc aggatgatgg ttcttgctat acgattgaac
    31381 atctgacatt agaccgcaaa acacttaaaa accactggca tcctttctat ttttataaag
    31441 gcgaatgtga gtacggattt aaaaattaac agccaaaatc acttatggcg ttccctgcgg
    31501 gccgggcttt cgtgctgcgc atcgagccag gcaagctgtc tcgccccttc gggcttcaat
    31561 ccctaacgcc tccgggcttt gccctccgcg ctccgcttgg cccccacgcc ctgcgccgga
    31621 cttgccccgc ctccggcggc cccgcccctt cggggtggct tcgccatcct ctgccagcaa
    31681 cggcgcaatc gtgcctgtag gggcgctggc cgctgcgcgg ccatcccccc aacacccgga
    31741 taaatcacgc ccggcccgtc gctacgcgcc agcccgcccg ctcaaccggg ccgttgtgac
    31801 gggccactgt tccggcggtg gtatcgtctg acagcccgcc aaaaccggct ttgcagggag
    31861 ggggtgggcg cttcgccctg gtcggcgtca ccggcgacgt aatgccctgc cccgttcggc
    31921 tccggggaag tgggcgcgtc gcccagctcg atgccgtaag gcccggcaat ttgaccacgc
    31981 cgcccaggtg gagatcggcg cagttgcctt tcatttgtcg gcagcggtgc aaaatttaag
    32041 tatctttttc gtactatata atgatactaa aagttgactt ttagaagggg aaagcctata
    32101 ctttatttat cggttagcaa tggtgctgac cggcccggaa ccagcggcgg caaccgctcc
    32161 gggaaaactg cgaaggaata aattatgagc gcatacgtag tatctgataa agccatttct
    32221 actatcgtta aaactctggt gctgaccggc acacttcagc ctgtcgaggc tgtttcattt
    32281 ggtcagatga tgcttaatct gaatacccat tctgttaatg ttcgctatca agaaagcagc
    32341 ccggcgcacg cttttgaata cagtgaaccg gaactaaata ttaacgaccc aaaaacacaa
    32401 attcaggtga ttgtctgcat tgatgagtat gaatatcagt cctgcgagtt tgccgaatac
    32461 tatgaaacga tggtgcatac agtcctcaaa gccataaaat cagcgttaca tgaggcttat
    32521 actgaaacat tgcctaatcc cgcccagtgg aaagctaaaa aatcctatga actgccgggc
    32581 tattcagaag ctgcatggag tttatgatcg cgcgggggta agccccccgc tctatctgta
    32641 ggggcgtagc cccttttttt gcgccggtga tctctggcgt cccctgcggg tcgggctttc
    32701 gtgctacaca tcgagccagg caagctgtct cgccccttcg ggcttcaatc cctaacgcct
    32761 ccgggcttcg ccctccgcac tccgcttggc ctccgggctt tgccctccgc gcttcgcttg
    32821 gctttttcag ccggtgccaa ctccgggccg cgaggataac cggcgggagg cgaactgtcc
    32881 tccacagctc cccgttccgt tggatggtct gccgttcctc cattaccggt attccacact
    32941 agcgcggtgt ggcgtcaata gttcgcttcg ccgcttcgcg ctattgaccc caccccttgc
    33001 gccagtgtta cacaccggtt gtcggaaacg acaaaccctc caactaccct acaggtgctt
    33061 tatggccgaa attctccaac tcctcccgcc ggttatcctc gctatcgcag ccctcatcac
    33121 agccatcacc ggcctgataa aagtcctgaa aagcaagaag aagtaacgga aaggggcggc
    33181 aagccgcccc tttcccctgc tcccctggct taccctgctg tacgatccgt ggatttcaca
    33241 gcagggttat tttgggtgat cgccgtgatt ggcccggcag cggccgccgg ttactcaggg
    33301 cgttccctgc gggccgggct ttcgtgctgc gcatcgagcc aggcaagctg tctcgcccct
    33361 tcgggcttca atccctaacg cctccgggct ttgccctccg cgctccgctt ggcccccacg
    33421 ccctgcgccg gacttgcccc gcctccggcg gccccgcccc ttcggggtgg cttcgccatc
    33481 ctctgccagc aacggcgcaa tcgtgcctgt aggggcgctg gccgctgcgc ggccatcccc
    33541 ccaacacccg gataaatcac gcccggcccg tcgctacgcg ccagcccgcc cgctcaaccg
    33601 ggccgttgtg acgggccact gttccggcgg tggtatcgtc tgacagcccg ccaaaaccgg
    33661 ctttgcaggg agggggtggg cgcttcgccc tggtcggcgt caccggcgac gtaatgccct
    33721 gccccgttcg gctccgggga agtgggcgcg tcgcccagct cgatgccgta aggcccggca
    33781 atttgaccac gccgcccagg tggagatcgg cgcagttgcc tttcatttgt cggcagcggt
    33841 gcaaaattta agtatctttt tcgtactata taatgatact aaaagttgac ttttagaggg
    33901 ggaaagccta tactttattt acggttagca atggtgctga ccggcccgga accagcggcg
    33961 gcaaccgctc cggg
//
