LOCUS       NZ_CP053637            25430 bp    DNA     circular CON 24-JUL-2023
DEFINITION  Staphylococcus aureus strain 14640 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP053637
VERSION     NZ_CP053637.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14375129
            Assembly: GCF_013305905.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 25430)
  AUTHORS   Tickler,I.A., Goering,R.V., Dewell,S., Le,V.M., Johar,L.,
            Obradovich,A.E. and Tenover,F.C.
  TITLE     Mobile genetic elements responsible for discordant Staphylococcus
            aureus phenotypes and genotypes in the same blood culture bottle
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25430)
  AUTHORS   Tickler,I.A., Goering,R.V., Dewell,S., Le,V.M., Johar,L.,
            Obradovich,A.E. and Tenover,F.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2020) Healthcare Associated Infections, Cepheid,
            904 Caribbean Drive, Sunnyvale, CA 94089, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1.00X
            Sequencing Technology :: Illumina Miseq/Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/24/2023 03:03:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,863
            CDSs (total)                      :: 2,784
            Genes (coding)                    :: 2,703
            CDSs (with protein)               :: 2,703
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 47 of 81
            Pseudo Genes (incomplete)         :: 35 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 26 of 81
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053637.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..25430
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="14640"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
                     /geo_loc_name="USA"
                     /collection_date="2016"
                     /note="isolate 1 from Case 2"
     gene            complement(join(25111..25430,1..46))
                     /locus_tag="HA037_RS14385"
     CDS             complement(join(25111..25430,1..46))
                     /locus_tag="HA037_RS14385"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="WP_001550107.1"
                     /translation="MFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYKIKSILKHGEK
                     NYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGGQEPESRMIEP
                     ISLGFYEQNWYLIGFAG"
                     /name="WYL domain-containing protein"
     gene            complement(528..1322)
                     /gene="aph(3')-IIIa"
                     /locus_tag="HA037_RS14105"
                     /old_locus_tag="HA037_14120"
     ARG             complement(532..1322)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(1415..1945)
                     /gene="sat4"
                     /locus_tag="HA037_RS14110"
                     /old_locus_tag="HA037_14125"
     ARG             complement(1419..1945)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(1942..>2577)
                     /locus_tag="HA037_RS14115"
                     /old_locus_tag="HA037_14130"
                     /pseudo=""
     CDS             complement(1942..>2577)
                     /locus_tag="HA037_RS14115"
                     /old_locus_tag="HA037_14130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(2718..3392)
                     /locus_tag="HA037_RS14120"
                     /old_locus_tag="HA037_14135"
     CDS             complement(2718..3392)
                     /locus_tag="HA037_RS14120"
                     /old_locus_tag="HA037_14135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(<3449..3625)
                     /locus_tag="HA037_RS14125"
                     /old_locus_tag="HA037_14140"
                     /pseudo=""
     CDS             complement(<3449..3625)
                     /locus_tag="HA037_RS14125"
                     /old_locus_tag="HA037_14140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(3639..4376)
                     /locus_tag="HA037_RS14130"
                     /old_locus_tag="HA037_14145"
     CDS             complement(3639..4376)
                     /locus_tag="HA037_RS14130"
                     /old_locus_tag="HA037_14145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(4369..5298)
                     /locus_tag="HA037_RS14135"
                     /old_locus_tag="HA037_14150"
     CDS             complement(4369..5298)
                     /locus_tag="HA037_RS14135"
                     /old_locus_tag="HA037_14150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(5414..6295)
                     /locus_tag="HA037_RS14140"
                     /old_locus_tag="HA037_14155"
                     /pseudo=""
     CDS             complement(5414..6295)
                     /locus_tag="HA037_RS14140"
                     /old_locus_tag="HA037_14155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(6292..>6669)
                     /locus_tag="HA037_RS14145"
                     /old_locus_tag="HA037_14160"
                     /pseudo=""
     CDS             complement(6292..>6669)
                     /locus_tag="HA037_RS14145"
                     /old_locus_tag="HA037_14160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(6727..7401)
                     /locus_tag="HA037_RS14150"
                     /old_locus_tag="HA037_14165"
     CDS             complement(6727..7401)
                     /locus_tag="HA037_RS14150"
                     /old_locus_tag="HA037_14165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            7875..9341
                     /gene="msr(A)"
                     /locus_tag="HA037_RS14155"
                     /old_locus_tag="HA037_14170"
     ARG             7876..9338
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9440..10339
                     /locus_tag="HA037_RS14160"
                     /old_locus_tag="HA037_14175"
     CDS             9440..10339
                     /locus_tag="HA037_RS14160"
                     /old_locus_tag="HA037_14175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(10808..11551)
                     /locus_tag="HA037_RS14165"
                     /old_locus_tag="HA037_14180"
     CDS             complement(10808..11551)
                     /locus_tag="HA037_RS14165"
                     /old_locus_tag="HA037_14180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            11977..12960
                     /locus_tag="HA037_RS14170"
                     /old_locus_tag="HA037_14185"
     CDS             11977..12960
                     /locus_tag="HA037_RS14170"
                     /old_locus_tag="HA037_14185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <12980..13269
                     /locus_tag="HA037_RS14175"
                     /old_locus_tag="HA037_14190"
                     /pseudo=""
     CDS             <12980..13269
                     /locus_tag="HA037_RS14175"
                     /old_locus_tag="HA037_14190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            13816..13965
                     /locus_tag="HA037_RS14180"
                     /old_locus_tag="HA037_14195"
     CDS             13816..13965
                     /locus_tag="HA037_RS14180"
                     /old_locus_tag="HA037_14195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(14133..14825)
                     /locus_tag="HA037_RS14185"
                     /old_locus_tag="HA037_14200"
     CDS             complement(14133..14825)
                     /locus_tag="HA037_RS14185"
                     /old_locus_tag="HA037_14200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            14935..15129
                     /locus_tag="HA037_RS14190"
                     /old_locus_tag="HA037_14205"
     CDS             14935..15129
                     /locus_tag="HA037_RS14190"
                     /old_locus_tag="HA037_14205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            16245..16862
                     /gene="cadD"
                     /locus_tag="HA037_RS14195"
                     /old_locus_tag="HA037_14210"
     ARG             16246..16859
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            16881..17228
                     /locus_tag="HA037_RS14200"
                     /old_locus_tag="HA037_14215"
     CDS             16881..17228
                     /locus_tag="HA037_RS14200"
                     /old_locus_tag="HA037_14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            17385..17477
                     /locus_tag="HA037_RS14205"
                     /old_locus_tag="HA037_14220"
     CDS             17385..17477
                     /locus_tag="HA037_RS14205"
                     /old_locus_tag="HA037_14220"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(17649..18620)
                     /locus_tag="HA037_RS14210"
                     /old_locus_tag="HA037_14225"
     CDS             complement(17649..18620)
                     /locus_tag="HA037_RS14210"
                     /old_locus_tag="HA037_14225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            18744..19163
                     /locus_tag="HA037_RS14215"
                     /old_locus_tag="HA037_14230"
     CDS             18744..19163
                     /locus_tag="HA037_RS14215"
                     /old_locus_tag="HA037_14230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(19677..20522)
                     /gene="blaZ"
                     /locus_tag="HA037_RS14220"
                     /old_locus_tag="HA037_14235"
     ARG             complement(19681..20522)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.29"
                     /coverage="100.0"
     gene            20629..22386
                     /gene="blaR1"
                     /locus_tag="HA037_RS14225"
                     /old_locus_tag="HA037_14240"
     ARG             20630..22383
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.8"
                     /coverage="100.0"
     gene            22376..22756
                     /gene="blaI"
                     /locus_tag="HA037_RS14230"
                     /old_locus_tag="HA037_14245"
     ARG             22377..22753
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            23020..23598
                     /locus_tag="HA037_RS14235"
                     /old_locus_tag="HA037_14250"
     CDS             23020..23598
                     /locus_tag="HA037_RS14235"
                     /old_locus_tag="HA037_14250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(23821..24006)
                     /locus_tag="HA037_RS14240"
                     /old_locus_tag="HA037_14255"
     CDS             complement(23821..24006)
                     /locus_tag="HA037_RS14240"
                     /old_locus_tag="HA037_14255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            24268..24942
                     /locus_tag="HA037_RS14245"
                     /old_locus_tag="HA037_14260"
     CDS             24268..24942
                     /locus_tag="HA037_RS14245"
                     /old_locus_tag="HA037_14260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     ARG             9441..10336
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             7876..9341
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             9441..10339
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(1416..1933)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(19678..20522)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="95.37"
                     /coverage="100.0"
     ARG             complement(2240..2541)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          13326..13473
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(10809..11551)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          11978..12960
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          13092..13261
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 atttccctgc tgtaatcaat gcacccactt ccgccgctgt aaacattacc ggcggaagta
       61 ggaagccctc tacaagaaaa tatccttttc cggcctcaga tccaattggt attccggctt
      121 cttcaagtgt ccggatatct ctgtaaactg tccttaagct tatattaaat cgctgtgcaa
      181 tttctttggc aggaattatt tttttgattg cagctgaata agaatagagg ttactctgtt
      241 aatcctgttc aaattttatt cctcctctgt gacttccata aaaagtatat cctatgcgtt
      301 cttaagctag ctgctgttag tgcttctcat tgcaccctgg ttataaaagc catactcaca
      361 aacctcttca ccaaaactct ttacatctct aatatagaac tctatctagc gaacttttag
      421 aaaagatata aaacatcaga gtatggacag ttgcggatgt acttcagaaa agattagatg
      481 tctaaaaagc ttgtagttaa agctttttag acatctaaat ctaggtacta aaacaattca
      541 tccagtaaaa tataatattt tattttctcc caatcaggct tgatccccag taagtcaaaa
      601 aatagctcga catactgttc ttccccgata tcctccctga tcgaccggac gcagaaggca
      661 atgtcatacc acttgtccgc cctgccgctt ctcccaagat caataaagcc acttactttg
      721 ccatctttca caaagatgtt gctgtctccc aggtcgccgt gggaaaagac aagttcctct
      781 tcgggctttt ccgtctttaa aaaatcatac agctcgcgcg gatctttaaa tggagtgtct
      841 tcttcccagt tttcgcaatc cacatcggcc agatcgttat tcagtaagta atccaattcg
      901 gctaagcggc tgtctaagct attcgtatag ggacaatccg atatgtcgat ggagtgaaag
      961 agcctgatgc actccgcata cagctcgata atcttttcag ggctttgttc atcttcatac
     1021 tcttccgagc aaaggacgcc atcggcctca ctcatgagca gattgctcca gccatcatgc
     1081 cgttcaaagt gcaggacctt tggaacaggc agctttcctt ccagccatag catcatgtcc
     1141 ttttcccgtt ccacatcata ggtggtccct ttataccggc tgtccgtcat ttttaaatat
     1201 aggttttcat tttctcccac cagcttatat accttagcag gagacattcc ttccgtatct
     1261 tttacgcagc ggtatttttc gatcagtttt ttcaattccg gtgatattct cattttagcc
     1321 atttattatt tccttcctct tttctacagt atttaaagat accccaagaa gctaattata
     1381 acaagacgaa ctccaattca ctgttccttg cattctaaaa ccttaaatac cagaaaacag
     1441 ctttttcaaa gttggcgtat aacatagtat cgacggagcc gattttgaaa ccacaattat
     1501 gatagaattt acaagctata aggttattgt cctgggtttc aagcattagt ccatgcaagt
     1561 ttttatgctt tgcccattct atagatatat tgataagcgc gctgcctatg ccttgccccc
     1621 tgaaatcctt acatacggcg atatcttcta tataagcgta ccggttccaa ttttttcgca
     1681 gtttaacttt tccgacgcat ttatcgtctt ggtagtaaag atatattatc ttatcagtat
     1741 tgtcaatata ttcaaggcaa tctgcctcct catcctcttc atcctcttcg tcttggtagc
     1801 tttttaaata tggcgcttca tagagtaatt ctgtaaaggt ccaattctcg ttttcatacc
     1861 tcggtataat cttacctatc acctcaaatg gttcgctggg tttatcgata tctttcaggt
     1921 gccctgcttt catttctgta atcactgttc ccgcctctct tctatatcag cggcatatgt
     1981 gctatccagg cagccggttt taccagtgta ttttttatac atgtccctgg tatattttgt
     2041 tatattccta tcatactccg gataggcata atgaagcctt tccgccacct caccggatac
     2101 cgccctgaac aattgatggc atagaaataa tgcttcccat atgttttcat aggaatccat
     2161 ccggtaggtg gacaaaagtt tctcccacaa atcctcggat atataccttt caataaactt
     2221 atagttcttg cctacacttc atttaaagcc tgtttcgatg ccgaccttcc atgatatcat
     2281 tctcagcagc tcatggcgaa caatctgatt aaaatgatca atagcaaata aaatttcctt
     2341 acggcacaat cctttaataa cataaggtgt tacattccaa aattcattgc agcaatcatc
     2401 atactccctt gcgcttggct ttcttacatg ataatctata tcagtcggaa ctatgtccct
     2461 tttaattcta caatctttat caattagaac ctttattaat ttatcgccct ttaggtaatt
     2521 atctaactct tccaagggca ataaggtaag atcaatttta ttgtaatcat caaatagcta
     2581 taatagattt agaggtaaag aaattaaata cattgaagag cagaaagatt ttacaaaaga
     2641 gtattttaat aaaaatgatg gttctgttgc aaagtaaaaa atatagctaa tcactaatat
     2701 atcatgtcag tgttcgttta acttgctagc atgatgctaa tttcgtggca tggggaaaat
     2761 ccgtagatct gaagagacct acggttcttt ttatatagag cgtaaataca ttcaatacct
     2821 tttaaagtat tctttgccgt attgatactt tgatatcttg tctttcttac tttaatatga
     2881 cggtgatctt gctcaatgag gttattcaga tatttcgatg tacaatgaca gtcaggttta
     2941 agtttaaaag ctttaattat tttagccatt gctgccttcg ttgaaggtgc ctgatctgta
     3001 actacctttt gaggcttacc aaattgttta atgagacgtt tgataaacgc atatgctgaa
     3061 tgattatctc gttgcttacg caaccaaata tctaatgtat gtccctctgt atcaatggca
     3121 cgatataaat agctccattt tccttttatt ttgatatacg tctcatcaat acgccatttg
     3181 taataagctt ttttatgctt tttcttccaa atttgatata aaattggggc atattcttga
     3241 acccaacggt agatcgttga atgatgaacg tttacaccac gttctcttaa tatttcagat
     3301 atatcacgat agctcaatgc atatcttaga tagtagccaa cggctacagt gataacatcc
     3361 ttgttaaatt gtttatatct gaaatagttc atacagaaga ctcctttttg ttaaaattat
     3421 attataaatt caactttgca acagaacctc ctaactgtat taccacctta aaagtagttg
     3481 cagacgcact tcctaaatcg tcagcagtgt ttaaccacat atcatcaaca ataatcatat
     3541 gacctgttga tgatactgga gcaaattctg tcaacccttc aactacacct aaaataaatg
     3601 ctttaatctg ctctataaaa cccatttttc tcctcctttt aacttatatc agttttttta
     3661 aagtatgaga ataatataat tacactgaat atagatgtaa caattatgat aattaaagat
     3721 aatagaaatg gataagtatt aggtaatgtt cctctagata tgtctccaac tgcagcccaa
     3781 ggaaataatc ctctatgttc agaattagca gtcattaaat ttatcaaagt aattattatg
     3841 gttaaaacaa ttgtgggaac ataattttta aaatatatcg acaaaataat tattggtgga
     3901 gataatatcc ataataacac tccgccaata acaaatgtaa agaatgaatc aattattaaa
     3961 ctctggctta acccttgaaa atgcaatagc atacctagca ttaaagttag caaccatgca
     4021 ataacagata gtgtttgaat ccacaagaat aataatatta ttttacttac taaaaaactt
     4081 tctctagata taggtataat taataagttt tttaaagtat cttctatata ttctcttcca
     4141 aacaaatagg ctattataac cccatataga ggaggtccaa taattagcat atgatataaa
     4201 ctgacttctt caaataactg tttaaataca atattaggag tcggtacttt cgtccgcata
     4261 ctaataaaag aagctacaac caccataaaa ggtgctacgc atgtacctaa aatacttatt
     4321 agaaacatat atgatctttt taacttaata aattctgtac ggagtagatt atccaattgt
     4381 gccacctcct actaagtctt cgaaataagt ttctagatta tcttctatca ctctcatctg
     4441 gaaaacatca atattgttta atactaataa tctattaatt tcttgttgtc tatcaatatg
     4501 tgaataaatt ttaaattcgc cattttcttt aattttatag tcataaattc cgaagttagt
     4561 ttccaacaaa catgcaactt tttcttcatc tgatactgat atacttataa attgtctgtt
     4621 cttttttttt aaatcttcat acataatttc ttctaacaaa actccgttat gaataatacc
     4681 caccttgtct actaactgct ctatttctga caatatatga cttgaaatta aaatggttat
     4741 atttctagat tgagccagat ccttaatcaa ctttctaatt tcttttatgc caataggatc
     4801 taatccattc gtcggctcat caagtatcaa taattcggga ttgtgcaata aagctctcgc
     4861 aatccctaaa cgttgcttca tacctaaaga ataattttta aacaatttta ctttttcaga
     4921 agctagtcct actatttcta acacttcttc aattgcattt tctttttgta tacctaatat
     4981 tttagcattt atagttaagt tctctttagc tgtcaaatta ctataaaaac ctggcgtttc
     5041 aaccatagca ccaatatttt ttaaaatttc agttttatta ctttcgaact ctttttcaaa
     5101 tattttaata ttacctttcg taggtttaat taagcctaaa agcattctta tagtagttgt
     5161 tttgcctgca ccatttcttc ctaaaaaacc ataaatttgt ccactttcaa cagttatact
     5221 caaattatta actgctatct gacttccata ttgctttgtt aagttattta tttcaattat
     5281 attattcaaa tttttcacct ctggcacctt tcttagtttg ttgttacctt tatcttacgc
     5341 gcgattagaa aaggctgcct ttatctattc ttacaaaaac agccgctaat cttacaaaaa
     5401 tgaaagattg gagttattta aattgaatgg tgaatattga accatcgttt aatgtagatg
     5461 tagcacttac tttatggcct aagcgctttg agattgtgct gacaatatat aaaccaatac
     5521 cgcttgattt ctcacttatt ctaccgttat agcccgagaa acctttatca aagattttcg
     5581 gtaaatcact cgcattaatg ccgataccgt tatctcggat tgataatttc tttgtatttt
     5641 cgtcaaacgt aatccacaca tctttgccac gtgcatattt taatgcattg tttaatattt
     5701 gctcaatcat aattgatgcc catttggcat ctgttaatat aaccgcttca cttttctcat
     5761 aatgcaactt tgtttgatga tgaataaact gtatcgcata acgtttaatc agtggtcgaa
     5821 ttaattcatc tacactcact tccataaaga ccatgtatgt cttttggttc atgagtttca
     5881 aatagttcag tgcaagattc gtgtaattat caatttgtaa gacttcatta cgcacgttag
     5941 aaatcacgtg ttcatcagga tcttcaagca gtaactttga tgctgtaatc ggtgtcttga
     6001 tttgatgcac ccacattaaa aaatatgact ctaactcact ttggtagtta ataaagtcat
     6061 tacgaagttt atggttttcg attcttaaat cttcgttctg ttcctgtagt gtttattctt
     6121 ttttaaagtt catgtaatgg ataccccagt aaatcattga aacaaacaat acaataccta
     6181 gaccaatcat atatgcttgc atcggcacat tatacatgaa taatataaag tagaataaag
     6241 cacaagtaag gatgacaata taaatttcac gttggattga tttcaagaaa ttcatacgtc
     6301 acctacacga tatccgacat ttttcttcgt ttcgataaaa tctgtaagtc ctagtttttg
     6361 tagctttttg cgtaaacgtg taatgttgac agcaagcgta ttgtcatcaa tgaagtgttc
     6421 tgattcccag catttttcga ttaacgcatt acgactgacg aatttgccct tgttctggaa
     6481 taagctatgc atgatttgca attcagtgtg tgtcaggtct atggtttctt cattaaattt
     6541 aagctttgct gcatcaagta gtaactcgca atcatctact gttaaattat taacttgagt
     6601 ggtgaaatca tacgtgcggc gtaatagtgc ttgaatctta gtaattgtaa cagtcatatt
     6661 aaatggctgg ttctgttgca aagtaaaaaa tatagctaat cactaatata tcatgtcagt
     6721 gttcgtttaa cttgctagca tgatgctaat ttcgtggcat ggggaaaatc cgtagatctg
     6781 aagagaccta cggttctttt tatatagagc gtaaatacat tcaatacctt ttaaagtatt
     6841 ctttgccgta ttgatacttt gatatcttgt ctttcttact ttaatatgac ggtgatcttg
     6901 ctcaatgagg ttattcagat atttcgatgt acaatgacag tcaggtttaa gtttaaaagc
     6961 tttaattatt ttagccattg ctgccttcgt tgaaggtgcc tgatctgtaa ctaccttttg
     7021 aggcttacca aattgtttaa tgagacgttt gataaacgca tatgctgaat gattatctcg
     7081 ttgcttacgc aaccaaatat ctaatgtatg tccctctgta tcaatggcac gatataaata
     7141 gctccatttt ccttttattt tgatatacgt ctcatcaata cgccatttgt aataagcttt
     7201 tttatgcttt ttcttccaaa tttgatataa aattggggca tattcttgaa cccaacggta
     7261 gatcgttgaa tgatgaacgt ttacaccacg ttctcttaat atttcagata tatcacgata
     7321 gctcaatgca tatcttagat agtagccaac ggctacagtg ataacatcct tgttaaattg
     7381 tttatatctg aaatagttca tacagaagac tcctttttgt taaaattata ttataaattc
     7441 aactttgcaa cagaaccgta ttttatgagt acactctaaa ttaaggagat gtataatcaa
     7501 tctaaaattg tatttttata cttttgttat ataatctttc tccttagaga tatattgtaa
     7561 aaaaaccaac aaaatgttat attaacatta ctattttatc gatgaaggag gattaaaatg
     7621 acagcttcta tgagactcaa ataaaccttt ttgaatacaa aactaaatta attcaaaaag
     7681 gcttgtccgc aatacacact cataggatga cttatgtcat tttttatcct tcgataggaa
     7741 taataaacgc tttcaaatac taaaacatca taataaattt ttaagtgttt gaaagtgtaa
     7801 tgtgaatgag acgggagtag cctgtctcat ttttttgcgt acacgtcctt taaatataca
     7861 aggagtgtat aaatatggaa caatatacaa ttaaatttaa ccaaatcaat cataaattga
     7921 cagatttacg atcacttaac atcggtcatc tttacgctta ccaatttgaa aaaatagcac
     7981 ttattggggg taatggtact ggcaaaacca cattactaaa tatgattgct caaaaaacaa
     8041 aaccagaatc tggaacagtt gaaacggttg gcgaaattca atattttgaa cagcttaaca
     8101 tggatgtgga aaatgatttt aacacgttag acggtagttt aatgagtgaa ctccatatac
     8161 ctatgcatac aaccgacagt atgagtggtg gtgaaaaagc aaaatataaa ttagctaatg
     8221 tcatatcaaa ttatagtccg atattacttt tagatgaacc tacaaatcac ttggataaaa
     8281 ttggtaaaga ttatctgaaa aatattttaa aatattacta tggtacttta attatagtaa
     8341 gtcatgatag agcacttata gaccaaattg ctgacacaat ttgggatata caagaagatg
     8401 gcacaataag agtgtttaaa ggtaattaca cacagtatca aaatcaatat gaacaagaac
     8461 agttagaaca acaacgtcaa tatgaacagt atataagtga aaaacaaaga ttgtcccaag
     8521 ccagtaaagc taaacgaaat caagcgcaac aaatggcaca agcatcatca aaacaaaaaa
     8581 acaaaagtat agcaccagat cgtttaagtg catcaaaaca aaaaggcacg gttgagaagg
     8641 ctgctcaaaa acaagctaag catattgaaa aaagaatgga acatttggaa gaagttgaaa
     8701 aaccacaaag ttatcatgaa ttcaatttcc cacaaaataa aatttatgat atccataata
     8761 attatccaat cattgcacaa aatctaacat tggttaaagg aagtcaaaaa ctgctaacac
     8821 aagtacgatt ccaaatacca tatggcaaaa atatagcgct cgtaggtgca aatggtgtag
     8881 gtaagacaac tttacttgaa gctatttacc accaaataga gggaattgat tgttctccta
     8941 aagtgcaaat ggcatactat cgtcaacttg cttatgaaga catgcgtgac gtttcattat
     9001 tgcaatattt aatggatgaa acggattcat cagaatcatt cagtagagct attttaaata
     9061 acttgggttt aaatgaagca cttgatcgtt cttgtaatgt tttgagtggt ggggaaagaa
     9121 cgaaattatc gttagcagta ttattttcaa cgaaagcgaa tatgttaatt ttggatgaac
     9181 caactaattt tttagatatt aaaacattag aagcattaga aatgtttatg aataaatatc
     9241 ctggaatcat tttgtttaca tcacatgata caaggtttgt taaacatgta tcagataaaa
     9301 aatgggaatt aacaggacaa tctcttcatg atataactta aaaactatac actaatttat
     9361 attgaatatt aggttcattt atatcaatat aaaaaatacg ttcacaagaa aaatataata
     9421 gaaataagga tccaataaaa tgactcgaca taatgaaatt attaaatgtg cagaaaaata
     9481 tcaattacac atccaacctc aaacaatctc attgaatgaa tcgggacttg attttcaagt
     9541 tgcatttgga aaagataaac atggagtaga atgggttttg agactaccaa gaagacctga
     9601 cgtttataaa cgaacaaaac ccgaaaaaca aacggtagac ttcttacaga agaatgtttc
     9661 atttgaaata ccgaagtgga aagtacatgc aaaagacctt attgcttacc caaaacttac
     9721 aggtaaaccc gcagccacaa tagatccaga aatacaaaat tatgtatggg aaattgaaca
     9781 caaaccatta ccagaaaact ttattaacac attagctgaa acactcgtag atttacacaa
     9841 cataccagaa gaaaacatta acgttcagca tataaatatc aaaaccatac aagaaataaa
     9901 aaatgacttt caaagaagaa tgaataaagt taaagaaact tatggcgtat cagatgaatt
     9961 atggaacaga tggaaacaat ggttagaaaa cgacgaacta tggcctcgac atgcgaccat
    10021 gatacatggg gacttacatc caggacatat aatggtagat aaccaagcaa acgtcacagg
    10081 tctcatagac tggactgaag caacccactc cgacccatca atggacttta taggacacca
    10141 tcgtgtattc gacgacgaag gattagagca acttataaca gcatacggta aagctggagg
    10201 tgaaatatgg ccacgaatga aagagcatat aatagaactc aatgcagtat tcccaatgtt
    10261 tatcgctgag tttgctatgg aatcaggaga atcggcgtat gaaacgatgg cattgaaaga
    10321 gttaggtatg aaagagtaga acttatatta aaagaggccc attttaaaga cgaaggcaat
    10381 cctgatgaaa ttttaaaact gcgtttaatt agtgatggtc tttggttttc tataatgtat
    10441 taaatatctg gacatggaac aaatgcaaca aatggaaaga atcgttttcg aaatttctaa
    10501 ctccttaaat caggaggata aataaacggt cattttcatt gaaagcactt atataaattt
    10561 catcaatttt aatacctacc gtaaatacat ttcataagta ttaaacagat gattaaaatt
    10621 tttagttaat ttaaatattt atgatagaga tgaccttcaa atgaacgttt ataacgcaat
    10681 catgatgaga gtattaatac agttaattat ttgaaatact ttagtttaca taatcgatga
    10741 ttaccagaag ttctcactat ataaaagaca ctaaaatttt ataactttta gtgcctaatc
    10801 aattatttta gctaccaaac aaacgactcc aaaacccctt tttaggttcc gtttcttcac
    10861 tcttttcttc tatatcacta tcattgtcat ttagattagc tggaacgtct tctttttttg
    10921 cttcttcacc ttgtgtactt tcgtcgcttt gacttccaga tatatcctta tattgaatct
    10981 ctgtttcttt agtttcttcc tgatctctgt taatatttac aggattagta gtatatgttt
    11041 tttcttgtgc atcaacgttt tgtctagtgt tagtagatgt atcaaaggga taattaaggt
    11101 gtttttcttt ttctaattga ttttctaatt tttgaatctt tttattactc tctaatgcca
    11161 gaacttgctg attttcaagc aattttgatc tttcttgcaa ctcttttctg taaaattcaa
    11221 ttgttgtttc atgacgactt tcttgttttt caatttgatt atttaaagta tcaatctgat
    11281 ttttaaggat ttctactatt tgagcatcgc ttttcgattc aaaattaata ttatccgacc
    11341 cttttttttg tttgtcttca gtagtacttt caaaaccata tttcttttta ttttcattta
    11401 ctctttgaat gattttttct atatcggtat cttctttaat aaacgaagtg ttttcctgtt
    11461 ttattgtctc tatattcaat cgcttaatat tattaaaaat cgtttgctta ctaaccccta
    11521 attcttcact caactttttc acacttttca tatcatcaac cctttataaa atgtttataa
    11581 acccttgata aaatattata agcttataat gcttaataat aaagtgatta ataaataaaa
    11641 ataaacatcc atcaaccttt ttatcaaggg tttatgaaag gtttatgata tttatcaagg
    11701 gtttataaac ccttgataaa gctatatttt cccttttata agtttattta aagtgctata
    11761 ataaacttaa tataacaaaa accccaacta ctggtaatag tcggggtttg gtaataaaac
    11821 gtttagaaac tgtttattta tataattttc gatacttgta ttatataatg aataatatct
    11881 tagtgcaagc acctaaatca ttaaataaat gtaaagctaa ataaaaacgt tttattacct
    11941 cttaccaaac taaaatatgg aaagaggttt tttgtcatgc aaaatcaata ttttacagtg
    12001 caagaaaatt acaaagaaag attttatcaa atccctaaag tattctttac cagtgaaaat
    12061 tataaaaatc taactaatga tatgaaaata gcctatgcta tcttacgtga tcgcttaaat
    12121 ttatctatta aaaatagctg ggttgatgaa gatggtaaca tttactttgt ttattcaaat
    12181 gaaaagctaa tggaaatctt aaattgtaaa aaagaaaagt taacaaaaat aaaaaaaggg
    12241 ttagaaaacg atggtctact cattcaaaaa cgacgtggtt taaataaacc aaatattcta
    12301 tatttaatga aacctattgt cacagaacgt gatatttaca aaatagaaaa agaagaaaac
    12361 gatgttgaac cttacggcga gaaggaagtt cgaaaatcga acgtccagaa gttcgaaaat
    12421 cgaacgtcca gaagttcgaa aatcgaacgt ccagaagttc gaaaatcgaa cactaatgat
    12481 actgacttta atgacattga ctttaatgat actgagaata atgatatgaa tgacttgaat
    12541 gatataaagt acaaaaatga aattagtaat cattcaaatc attcaaatca atttacacat
    12601 aattttgatg ataaagaaat gctattgcaa gaattcccag aacaactaac taattattta
    12661 ttaaaatatg attatagaga tttagaaatc ataaaggctg ttattcttaa agcaaaaaaa
    12721 tcatttaatt caaggcatga agatatgcat tacatgttag aggacattga ggatgaaata
    12781 ttaacttctt taaaaagact taaaaaagct atacatgata ggggagttaa aggccaaaag
    12841 gaaacaatca agtcaatgca agcttattta atgcaaacaa ttctaactga acttgaagaa
    12901 acacatgccc tttatatgcg ccgtaaaaac atgaaacaat ataatatctt taatcaataa
    12961 ttcaaatgat tttataacac tcgaagagac atcaaaatat tccgttaaat catctgactt
    13021 tttaactgat gacgacgaaa aaaatcaaga aattgtaagt gatttagaaa aaggtttgta
    13081 tcgaaaacgt atgttaagtt atggtggatt gcttaaacaa aagcataaaa ttttaaactt
    13141 agacgatgcc gaagatggta atttgattaa tacaagtgat gaagataaaa cgacagacga
    13201 agaaaaaaag cacattcaat taccgcaatt tggaatttcg aaaagcaaaa ttattattta
    13261 agacattagt gataactgat gtcttttttt attgtttttc tgtaaaaaag tgctgtctta
    13321 tttttgtgac aaatgctgta tgtagtgtca caaaagtgtg acactacagc tttgtatgat
    13381 atcactttaa aataacttaa aacccttgga atgtctggcc ttgccagatc tatcattttt
    13441 gaatgatagc aaatttccct tatgctctta cggagatttt agagttaaat taaaatttct
    13501 aagtttttga taagaaaagc cctgcaggaa tttagaaaaa catggggaag ttttaaagta
    13561 ttttatgcta atttttaaat ttgcatgtaa atgggcagta tctaaaaaat tagtcactga
    13621 ttttgctgaa atttttgttt gtgaaattag catatattta tttggctcat atttgcgttt
    13681 taagagactg tatagatttt taagtacaaa acctatatga tttgcctcta agtcttcaaa
    13741 atgcctctta aaatccaaaa taaaagtgtt taatattgta ataaggattg ctatttttat
    13801 aaaaggagag atatcatgaa gattaaaact ttcgctactt ttactcatcg tcaattagat
    13861 aaacaagtta ataggttttt aaagaatgat attcatgtat tagaaattca aacacacagt
    13921 aattggttat atatttcagc tattgttttt tatgaggata aataaggaac atcgtattta
    13981 tgccgaaaaa atttattgat gttgagaaga acccttaact aaacttgcag acgaatgtcg
    14041 gcatagcgtg agctattaag ccgaccattc gacaagtttt gggattgtta agggttccga
    14101 ggctcaacgt caataaaaca attggaataa aatcaaccta cagagcatcc agctgcaaat
    14161 gcagttccgc aaactgcttc acatacaccg ccggctattg gatttacgat tgcccatact
    14221 ccacagtagt gagcacatgc ataaagtcca gccatactac aagcgaatgc tttgccgttc
    14281 catttgaatc ctgcatatgt taccggtctg tttttatcaa ctttttcagc cttatattca
    14341 acgtaatttt tgttaataag tatttttccc tctttgtttt cagtcatact tcttttttcg
    14401 gcaatgaatt ttgtgatttt tttgttgtag ttatcatata ttgtttcaga aactacaatt
    14461 tcttttgttt tttcattttt ataagcgtta ttagctatgt agccatatgc atttttatca
    14521 tttgcttctg tagctagata ttttaattta gaatttttgt cttctagctt tattttttta
    14581 aatccttctt ttttcatttg cttttcgaat ttttgcatat cttcattttt attttgcaat
    14641 tgttctagaa aacttatttc tttcttggtc atttgtgata cttcgatgtt tttgcttttc
    14701 aatttttctt tttgattttc tagtaaagaa cttttttgtt cttcatttgc gtaagcatta
    14761 gaaaaattcg cgctaaatac cagtaggaac aaggaaatta ttgaaaataa ttttataatt
    14821 ttcatttgat acctccaaga taataagata ttttaattgt ataagtaagc gctttataaa
    14881 atcaatattt attttaatat atttataaac atatttttga aaggagtcta ttttatgaat
    14941 gaaaatttag aaaaatatat aaaaagtttg ccacttttag gtttgttaat tagtattttg
    15001 ttaattgttt tattcttttt tattttagat gttgatgaag atttattcgt ggttttttta
    15061 tactgtttat tgcctttgat agttaatttg tctatttatg gtttttatgt ttttgttaaa
    15121 agaaagtaag attatgaata attttgtttt taatttgtat gctttgaggg ggttggaaaa
    15181 cggtaggtgt atagattaga tttcttgttt ttttgaaacg agtgtgaacg agtttcttct
    15241 tgtcttgatt tttgataaaa acgccctaca ggaatttaga aaaacgtggg gaagttttaa
    15301 agaattttat gctaattttt aatttgcatg taaatgggca gtgtctaaaa atagttattg
    15361 tttttgctca aatttttgtt tttgaaaata gcatatattt atttggctca tatttgcgtt
    15421 ttaaaagcat atataagttt tagatataaa actatatgaa tcacccctaa atctttaaaa
    15481 tgccctctta aaattcaaaa taagggcata aaaaataaaa gctaccccag ataaagtgag
    15541 gtagcttttt ctttcatacg gtctatttat ttttctttcg acgccgtatc gtcgatgtaa
    15601 ttcaaaaaag ttatgggcta taaatctaca tcactttttc aagaatgtag tagcaatatt
    15661 caacgcaaat taatttttat aactgctcgg aatatctcaa gccgtttctt taattttgaa
    15721 ataaaaaaat cgacgaaggt cgattacgtt tttgcacatg tcgatttatc cgacgtataa
    15781 gtgcgccctt acgggattta actagattat aacgacgaat tttagacctg taaagcaata
    15841 acaattaggt ctaccaggta gataaagtgt acaaaataga accgaaaaag ttatttattt
    15901 tgaagatttt tcgtagatat aatttgctaa taaacttcct aaaactgaat aaagaaaaat
    15961 agttaaactc atgtaatcac tccataattc tgaagtgtct ccatgtctac gcatagacac
    16021 gcatttatgc cgaaaaaatt tattgatgtt gagaagaacc cttaactaaa cttgcagacg
    16081 aatgtcggca tagcgtgagc tattaagccg accattcgac aagttttggg attgttaagg
    16141 gttccgaggc tcaacgtcaa taaagcaatt ggaataaagc acctatgatt atttaaaaat
    16201 ataagttata atacattcaa aaatattttt gaatgaggtg tattatgatt caaacggttg
    16261 ttgctgctgc tgttctttat attgctacag cagttgattt attagtaatt ttattaatat
    16321 tttttgctag agcaaagact agaaaagaat atagagatat ttatgttggt caatatttag
    16381 ggtctattat tttaatatta gttagtttgt ttttagcttt tgtattaaat tatgttccag
    16441 aaaagtggat attaggttta ttgggtttaa taccaattta tcttggaatt aaagtggcta
    16501 tttatgatga ttgtgaagga gaaaagagag ctaaaaaaga attgaatgaa aaaggattgt
    16561 ctaaattagt tggtacggtt gcaattgtta cgatagcaag ttgtggcgcc gataatattg
    16621 gtttatttgt tccgtatttt gtgacattaa gtgttactaa tttattactt actctgtttg
    16681 tctttttaat tttaattttc ttcttggtgt ttactgcaca aaaattagct aatattccag
    16741 gaattggaga aattgttgag aaatttagtc gttggattat ggctattatt tatatagctt
    16801 taggtttatt tattattatt gaaaatgaca ctattcaaac aattttagga tttatatttt
    16861 aatttagggt gtgattttat atgagttatg aaaatacttg tgatgtgatc tgtgtacatg
    16921 aggataaagt taacaatgct ttaagttttt tagaagatga taaatctaag aaattactta
    16981 acattttaga aaaaatttgt gatgagaaga aattgaaaat catattatct ttgattaaag
    17041 aagatgagtt gtgtgtttgt gatatttctt tgatattgaa aatgagtgtt gcttcaactt
    17101 cacatcattt aaggctttta tataaaaatg aggtacttga tttttataaa gatggaaaga
    17161 tggcatatta ttttattaaa gacgatgaaa taagagagtt tttctctaaa aatcatgagg
    17221 gtttttgaaa cgagtttctt cttgtcttga tactataaaa aacaaagtta tataacataa
    17281 gacgacttat cggaagtaga tatgcttgta tattcacaga tggtataata atagagtcgc
    17341 ctatctctca ggcgtcaatt gacgaagaga ggaggtgcat tactttgcta atcattttcg
    17401 ttcacatcat agcaccagtc atcagtggct gtgctgttgc gtattatact tattggctta
    17461 gtaaacgcaa caaataatta ataggcgact ttataagcca gcatcgaaaa aatccccaca
    17521 ctactgcaat agtgtgggga ttggtgcatt aattgttaat cattttcgtt atataaatta
    17581 taacactggt tagtagagaa atgcaaaatg attgaattaa tagtaaatgt attaatgaat
    17641 actcacactt atacttttaa aatagttctt cctaaatgtt gtccttttaa aagctgatct
    17701 atcgttttat agaattcttc aaatccaatt tcattgtata gaagtgaatt tcctatattc
    17761 cattcatttg ctaacttact ccatatatct tcacggatat tatgatcaac atatacagaa
    17821 tcaatgccaa ttaatttaat acctctaaga ataaacggta atatattagc gttaagtgaa
    17881 tttcctgcta catttccaca tacagtagca acaccttgat aatttagacg ttttaaaccg
    17941 tataatgtta cattactccc cactgtatct aagaaataat caaaaatacc ttttttaagc
    18001 ggtttattat catcttcaat tattattact tgttttgcac ctaatttttt tgcgatttct
    18061 atttgctttt cttttcttac gatagcagtg atattttcat atccaatttt atgtaaaatt
    18121 tgtatagcaa cactgcccac accacctgta gccccagaca ctaaaatttc aggttgtgat
    18181 ttgatattca ttccatattt ttctagttca aaaattgata atgctgccgt aaaaccggct
    18241 gtgccatata ccatagactc tttaatagac atttcttggg gaataggaac aatccactct
    18301 ccaggcactt gtgcatattc tgaaaatcca cctgtatgtg tcacgccaac atcataacca
    18361 gtaactaata cattatcgcc ttctttaaac ttatcattcg aacttgattc aacaatacct
    18421 gcaaaatcta taccaggaat cataggataa tctctaatta caccgccttt atattgtaaa
    18481 gctagcatat ccttataatt tattgaagag tataccactt ttactaatac atcacccttc
    18541 gataaatgag attcatcaac tttttctact ttataactaa catttgatgc actttttctc
    18601 actactaccg cattgaacat ttattagcct tctttcacaa ttgttttgta gaagtatgtt
    18661 tttgttgcaa aactattttc ctacaaaact tatcatgata tgataagcga gtcaatacta
    18721 atgatttaag agaggtttta gttgtggaat tagataattg tataaattat ttgttgagta
    18781 cttctcagaa tagagttttt aaacatttta aaagtttatt aagtccctat aatattactc
    18841 cagcagaata tggtgttttg aattgcttga ttaatagtaa tttgaataca cctaaagcga
    18901 ttggtaatac tttaaattta gaaccttcaa caatatctgg aatattagat aagatgtcca
    18961 aaaaggatct aataacacgt caaactgata atgaaaatag aagaactgtg ctaataaaca
    19021 gtacaaataa agcaaaagac ttatggccaa cattagaaaa gaaagcctat caacttaata
    19081 atcattactt cgctaattta actaatgaag aaactgtagt gtttaaaaag atattactaa
    19141 agataaataa aactacgttt taatttttac gttataaaaa agttgaagtg cgaattataa
    19201 tcgagtaaat ataaatgata gcttagctta attatatatt aaagccaact atacttttat
    19261 tcccgaaaaa cctactatcc aaatttctaa gatactttag cctctataat aaacatattg
    19321 taatataatt tatgtattat ttaggtttac cctaatcgaa caataaaaaa tacttgtaaa
    19381 atgctattgt cactttgctt gatatatgag aattatttaa ccttataaat gagaaaaaag
    19441 caacgcactt taaataagat acgttgcttt ttcgattgat gaatacctat aattaaacta
    19501 ttcatctatt atttatgatt ttttgtatat acaatatttc tagtttgtta aagagaatta
    19561 agaaaataaa tatcgaaaat aatagaggga aaatcagttt ttgatatcaa aattatacat
    19621 gtcaacgata atacaaacta taagatgata tcagtattta ttatgcattt agaatattaa
    19681 aattccttca ttacactctt ggcggtttca cttatcaact tatcatttgg cttatcactt
    19741 ttattgtctt tattcgtaaa aatgactaaa acaataggtt cagattggcc cttaggataa
    19801 acaaaagcaa catcatttct agaagcatat gttattgctt gaccactttt atcagcaacc
    19861 ttacagtctt ttgaaacacc gtctttaatt aaagtatctc cgcttttatt atttaacatt
    19921 aaatcaagta agaatttttt gttttctttg cttaattttc catttgcgat aagtttattt
    19981 aaagtcttac cgaaagcagc aggtgttgaa gtatcttttt tgctctttgg tgaataataa
    20041 tttaattcta tctcatatct aactggattt gttactttat ctcctagtcc ttttagacgt
    20101 tgtttaactt ttttgatccc accgatctct tttataattt tattgtttgc tgtattatca
    20161 ctatatgcca ttgaagcctc aataagttct tttaaagtga tatcttttcc tacatatttt
    20221 tctaaaatag gagaataagc aactatatca tctttgttaa tatgtatttt tttatttaac
    20281 ttattataag gtacttgttc taacaaaata gcactattta tcgcttttga agtcgaagca
    20341 taggcaaatc tcttatctga attaaatttt acttccttac cacttttagt atctaaagca
    20401 taaacaccaa tatgagcatt atattttttt tctaaatcat ttaactcttt ggcatgtgaa
    20461 ctgtttgaat tacatgcact taaaactaaa gcaattacaa ttaaaaatat taactttttc
    20521 aaaataaacc ctccgatatt acagttgtaa tttttataaa tcaataatat tacaattgta
    20581 atattgatgt caattgttta ttataaatat ttgaaagaag gtgtcaaaat ggctaaatta
    20641 ctaataatga gcgtagtaag cttttgtttt atatttctat tgttagtatt ttttaggtac
    20701 atattaaaac gctattttaa ttatagttta aattataaag tttggtatct aactatgctt
    20761 gctggattaa ttccttttat cccaattaaa ttctctttta taaaatttaa taatgtgaat
    20821 aatcaagcgc ccacagttga aagtaagtca cacgatttga accataacat aaataccacc
    20881 aaacctattc aagagttcac aacagatatc cataagttta attgggattc aattgataat
    20941 atctgcacag ttatttggat agttttagtt attattttaa gttttaaatt tttgaaagcc
    21001 ttattatatc ttaaatattt aaagaaacag tcactttatc taaacgaaaa tgaaaaaaat
    21061 aaaatagata cgatactttt caaccatcaa tataaaaaaa atattgtgat tcgaaaagca
    21121 gaggctattc aatctccaat aactttttgg tatgggaaat atattatttt gattcctagt
    21181 tcatatttta aaagtgtaat tgataaaaga ctaaaatata taatactgca tgaatatgct
    21241 catgctaaaa atagagatac tttacattta attatcttta atatcttctc tattgttatg
    21301 agttacaatc cattaataca tattgtaaaa agaaagataa ttcatgacaa tgaagtagaa
    21361 gctgatagat ttgttcttaa taatattaac aaaaatgaat ttaaaactta tgcggaatct
    21421 attatggact ccgtattaaa tattccattt tttaataaaa atatattaag ccattcattt
    21481 aatggtaaaa agtcattact caaaagaaga ttaattaata taaaagaagc caatttgaaa
    21541 aaacagtcta aattaattcc aatttttatt tgtattttta cttttttgct catagtaatt
    21601 caaagccagt ttttgatggg gcaatccata actgattata attataaaaa gcccttacag
    21661 aacgatcacc aaattttaga tgaaagtaaa aattttggtt caaatagtgg atctttcgtc
    21721 atgtacagca tgaagaaaga caaatactat atttataatg aaaaagaaag tagaaaaaga
    21781 tattctcctg attcaactta taaaatttat ttagcgatgt ttggacttga ccgtcatatc
    21841 ataagtgata aaaattcacg tatgtcatgg aatcataaac attatccttt cgagtcttgg
    21901 aataaggaac aagatttaaa tacagcaatg caaaattcag ttaattggta cttcgaacgt
    21961 attagtaatc aaataccaaa gaactatact gcggctcaac tcaagcaatt aaattatggt
    22021 aatgaaaatt tgggaagtta taaaaactat tggatggaag atagtttgaa aatatctaat
    22081 cttgaacaag taatagtttt taaaaatatg atggaacaaa ataaccattt tagtaaaaaa
    22141 gcaaagaatc aattatcttc ttcattattg attaagaaaa atgaaaagta tgaactgtat
    22201 gggaaaacag gtacaggtat agtaaacggg aagtataata atgggtggtt tgtaggttac
    22261 gtaattacaa atcatgataa gtattatttt gctacacatt tatcagatgg aaacccgtct
    22321 gggaaaaatg ctgaattaat cagtgaaaaa atattaaaag aaatgggtgt tttaaatggc
    22381 caataagcaa gttgaaatat ctatggctga atgggatgtt atgaatataa tatgggataa
    22441 aaaatcagta tcagctaatg aaattgtagt tgaaattcaa aaatataaag aagttagcga
    22501 taaaacaatt agaacattaa tcacaagact atataaaaaa gagattataa aacgatacaa
    22561 atcagagaat atttattttt actcatcaaa tattaaagaa gacgatatta aaatgaaaac
    22621 tgctaaaact tttcttaata aactgtatgg aggggacatg aaaagtttag tgctaaattt
    22681 tgcgaaaaat gaagaattaa ataacaaaga aattgaagaa ttgcgagaca ttttaaatga
    22741 tattagtaaa aagtaattag agatatgttt caaacattat acatatgtaa actatacttg
    22801 actcttatta aattagtttt gttaataaca tttaaaatat attagtaaag atgagagtgt
    22861 acataaaata accattttct gtacactctc tttttatgtc taaataagta tgtattacat
    22921 agaattatgt gttcaaaaac ccaacaaaaa atctatgttc acaaaagacc tcgtaatcaa
    22981 gttatggtac actaaaggtg tatataggag gtctgtattt tgaaaatagg ttatgcaaga
    23041 gtttcaactg gattacaaaa tttgaattta caggaggatc gattaaatac atatggttgt
    23101 gaaaagatat ttaatgacca tatgagtggt tcaaaaagta agcgacctgg tttagataaa
    23161 gcaattgaat ttgcgaggtc aggagatacg attgttgttt ggagattaga tagactagga
    23221 cggaacatgg aggatttaat cacgttagtt aatgaactta acgaacgagg tgtgagtttt
    23281 catagtttag aagaaaatat aacgatggat aaatcaagtt ctacaggaca attattattt
    23341 catttattcg cagcatttgc agagtttgaa cgtaatttaa ttttagagcg atcatcagcc
    23401 ggtcgaattg cagcacgtgc tagaggccga tatggaggta gacctgaaaa attaaataaa
    23461 caagatttaa acttacttaa gacactttat gataatggta cgccaattaa aacaattgca
    23521 gagcagtggc aagtttcacg tacaactatt tatcgttatc tcaataaatt agaggcaaaa
    23581 gagaataaaa acaagtagag caactaatct agcttactat aatgaatcta ctaaataatt
    23641 ttatatatca ttaacataca aagactttga ttcaatgtca ctcgatgtaa aagagacgtt
    23701 ctgacagcgt ctaaaatctc ataatatttt cctgttatga gattttaata ataacacaag
    23761 aaaaaagcgt acaaattcgt acgctttttt aatataatac ctgtttcact aatgaacgtt
    23821 ttaagtatct tcatcattaa ctgaaactac agtaataata ctcgtcaaca atattagtat
    23881 agttaaaata gaaagactta ggactggcat aaccgaacta aaattatatt tgaaatataa
    23941 aagtgctaat gaagagagaa atgtaaaaat aataaatacc aaagaccatt tttctaattt
    24001 attcattggc ttcacctctt tgaactttta tataatcata ggagatattt ttactacgat
    24061 ttataaaaaa taagaagata atcattatta aagaaacgat taatataatg ttgaatccta
    24121 tagtatcacc taattcgttt acacctttgc ctaatatcgg agatacaaag ctttgtatta
    24181 ataatgaaag agatgcccat atagtaaatg aggttctgtt gcaaagttga atttatagta
    24241 taattttaac aaaaaggagt cttctgtatg aactatttca gatataaaca atttaacaag
    24301 gatgttatca ctgtagctgt tggctactat ctaagatatg cattgagtta tcgtgatata
    24361 tctgaaatat taagggaacg tggtgtaaac gttcatcatt caacggtcta ccgttgggtt
    24421 caagaatatg ccccaatttt atatcaaatt tggaagaaaa agcataaaaa agcttattac
    24481 aaatggcgta ttgatgagac gtacatcaaa ataaaaggaa aatggagcta tttatatcgt
    24541 gccattgatg cagagggaca tacattagat atttggttgc gtaagcaacg agataatcat
    24601 tcagcatatg cgtttatcaa acgtctcatt aaacaatttg gtaaacctca aaaggtaatt
    24661 acagatcagg caccttcaac gaaggtagca atggttaaag taattaaagc ttttaaactt
    24721 aaacctgact gccattgtac atcgaaatat ctgaataacc tcattgagca agatcaccgt
    24781 catattaaag taagaaagac aaggtatcaa agtatcaata cagcaaagaa tactttaaaa
    24841 ggtattgagt gtatttacgc tctatataaa aagaaccgca ggtctcttca gatctacgga
    24901 ttttcgccat gccacgaaat tagcatcatg ctagcaagtt aagcgaacac tgacatgata
    24961 aattagtggt tagctatatt tttttacttt gcaacagaac cagcatttgt tttaatattt
    25021 gttccaaaga gccatcatgg ctttgacaga gctcttcttc tatgcaaatg cttttaatcc
    25081 gatccacacg aaaattccta tattcatttc ttagcctgca aaaccgatta agtaccagtt
    25141 ctgttcataa aaccccagtg atataggctc tatcattctg ctttccggtt cttgccctcc
    25201 tgatgcagga tattgaattg atattaccct tttattgcag attgcagtct gaattgctgc
    25261 aataacgtta tccgccaatg tatttttctg tccagatgtg ctgtacacgt taatactgtt
    25321 ctccaactcc tgtgcatagt ttttttcacc atgcttcaaa atagatttga ttttatacat
    25381 agctgaatca aaatccttta taaatgattc atctccatgg caatttaaaa
//
