LOCUS       NZ_CP053076            25664 bp    DNA     circular CON 23-MAY-2024
DEFINITION  Staphylococcus aureus strain SA01 plasmid pSA01-tet, complete
            sequence.
ACCESSION   NZ_CP053076
VERSION     NZ_CP053076.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14820654
            Assembly: GCF_013004085.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 25664)
  AUTHORS   Zhu,Y., Wang,C., Schwarz,S., Liu,W. and Zhang,W.
  TITLE     Analysis of a multiresistant Staphylococcus aureus strain of chicken
            origin
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25664)
  AUTHORS   Zhu,Y., Wang,C., Schwarz,S., Liu,W. and Zhang,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2020) Harbin Veterinary Research Institute,
            Chinese Academy of Agricultural Sciences, No. 678 Ha Ping Road,
            Xiang Fang District, Harbin, Heilongjiang 150069, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_013004085.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 04:39:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,966
            CDSs (total)                      :: 2,883
            Genes (coding)                    :: 2,782
            CDSs (with protein)               :: 2,782
            Genes (RNA)                       :: 83
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 53 of 101
            Pseudo Genes (incomplete)         :: 43 of 101
            Pseudo Genes (internal stop)      :: 37 of 101
            Pseudo Genes (multiple problems)  :: 29 of 101
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP053076.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..25664
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="SA01"
                     /host="chicken"
                     /db_xref="taxon:1280"
                     /plasmid="pSA01-tet"
                     /geo_loc_name="China: Heilongjiang"
                     /collection_date="2019-07"
     gene            1..960
                     /locus_tag="HK402_RS14495"
                     /old_locus_tag="HK402_14510"
     CDS             1..960
                     /locus_tag="HK402_RS14495"
                     /old_locus_tag="HK402_14510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_170172421.1"
                     /translation="MSNFKRITIQEFEQERFYKLYKFLFEDDYFRKLSDSAKIAYCIFR
                     DRFELSKINNWIDQNGNVYLIFTTKDLCNLLNCGTQKVTKIKKELESFNLLEQERMGLN
                     KPNKIYILEPKKPSKLNDIKEFRKSKFQSDENQNSGILKVKKQEFRKSKSNDTNLNNTD
                     YIETEHNDMNDLNDTYNNISIDHTHSNQPNQFLNNFGNQDDKEILLQEFPDQLTSYLLN
                     YSYTDLEIIKSVILKAKKSFNSNHDDTYYMLEHIEDEILIALKRVKKAIHDRGVKGQKE
                     TISSMQGYLMRTILSELEESYSVDMRRQNMAKYNIFNQ"
                     /name="replication initiator protein A"
     gene            <974..1279
                     /locus_tag="HK402_RS14500"
                     /old_locus_tag="HK402_14515"
                     /pseudo=""
     CDS             <974..1279
                     /locus_tag="HK402_RS14500"
                     /old_locus_tag="HK402_14515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001568503.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            1923..2438
                     /locus_tag="HK402_RS14505"
                     /old_locus_tag="HK402_14520"
     CDS             1923..2438
                     /locus_tag="HK402_RS14505"
                     /old_locus_tag="HK402_14520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017000767.1"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_170172422.1"
                     /translation="MDEFYLIDSPSFEKLKDLKNEYSNLDITSVLLYLEIQKAYKKMKL
                     NHDVFLQKFDLSESKFTIMMLLSYEKDMTLSPSNLSEKIGSKKSTITGVLKGLEKNGLV
                     EREVLSHDKRTNYVQLTDLGLRKLKEFLPYNYEVVSKVFEVFSEQEKEEFYRLANKLKN
                     NLEKDDLF"
                     /name="MarR family transcriptional regulator"
     gene            2435..2794
                     /locus_tag="HK402_RS14510"
                     /old_locus_tag="HK402_14525"
     CDS             2435..2794
                     /locus_tag="HK402_RS14510"
                     /old_locus_tag="HK402_14525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002492756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_170172423.1"
                     /translation="MNKVEFLETFLSLYINHHEVLKDMENGTGKYVIIDVRNAPKKVKK
                     DKIKNSVEIPAKDLKNHLSSLDKDKIYVVYDWTGGTILGKAALLDFYRNGFEAYELAGA
                     LEGWKGMSLPLEDVE"
                     /name="rhodanese-like domain-containing protein"
     gene            complement(3920..4009)
                     /locus_tag="HK402_RS14915"
     CDS             complement(3920..4009)
                     /locus_tag="HK402_RS14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_240955264.1"
                     /translation="MYIEKGQHTNVCYPNEPVKKTVTYNLNYY"
                     /name="hypothetical protein"
     gene            complement(4085..4351)
                     /locus_tag="HK402_RS14515"
                     /old_locus_tag="HK402_14530"
     CDS             complement(4085..4351)
                     /locus_tag="HK402_RS14515"
                     /old_locus_tag="HK402_14530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501215.1"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_170172424.1"
                     /translation="MDNYSISIKNSAKSDLKKIKQSQLKTQFLKIVDTLKEDPYFPNQS
                     FEKLQPKHLGRYSRRINHQHRVVYTVDEDDKEVFILSAWSHYE"
                     /name="Txe/YoeB family addiction module toxin"
     gene            complement(4352..4609)
                     /locus_tag="HK402_RS14520"
                     /old_locus_tag="HK402_14535"
     CDS             complement(4352..4609)
                     /locus_tag="HK402_RS14520"
                     /old_locus_tag="HK402_14535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587616.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_069822313.1"
                     /translation="MNIKTPTNARKEFYELLKQVNDSHEPVIISSSKSENNAVIISQKD
                     WDSIQETLYLETTGTMDKVREREKDNSGYTNIDDIDWDNL"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            4812..4904
                     /locus_tag="HK402_RS14525"
                     /old_locus_tag="HK402_14540"
     CDS             4812..4904
                     /locus_tag="HK402_RS14525"
                     /old_locus_tag="HK402_14540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_023016171.1"
                     /translation="MAILFVSIIAPVISGCIVAIFTFWLNNRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5064..5201)
                     /locus_tag="HK402_RS14530"
                     /old_locus_tag="HK402_14545"
     CDS             complement(5064..5201)
                     /locus_tag="HK402_RS14530"
                     /old_locus_tag="HK402_14545"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_170172425.1"
                     /translation="MVTEGMTKSSAMVHDESPAIGRMIPSLEEMQGDLKKLDSFKKEFN
                     "
                     /name="hypothetical protein"
     gene            5430..6413
                     /locus_tag="HK402_RS14535"
                     /old_locus_tag="HK402_14550"
     CDS             5430..6413
                     /locus_tag="HK402_RS14535"
                     /old_locus_tag="HK402_14550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_000336291.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHIL
                     EFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKVVA
                     EVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQGFRRMMQYKKINKNLVGFMRATE
                     VTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKVQMIR
                     PKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYGGLLKE
                     IHKKLNLDDTEEGDLIHTDDDEKADEDGFSIIAMWNWERKNYFIKE"
                     /name="protein rep"
     gene            6573..7343
                     /gene="aadD1"
                     /locus_tag="HK402_RS14540"
                     /old_locus_tag="HK402_14555"
     ARG             6574..7340
                     /name="aadD1"
                     /gene="aadD1"
                     /gene_name="aminoglycoside O-nucleotidyltransferase
                     ANT(4')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            7669..8343
                     /locus_tag="HK402_RS14545"
                     /old_locus_tag="HK402_14560"
     CDS             7669..8343
                     /locus_tag="HK402_RS14545"
                     /old_locus_tag="HK402_14560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_113589581.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKHTLKGIECIYALYKKNRRSLQIYGFLPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(8423..9157)
                     /gene="erm(C)"
                     /locus_tag="HK402_RS14550"
                     /old_locus_tag="HK402_14565"
     ARG             complement(8427..9157)
                     /name="erm(C)"
                     /gene="erm(C)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(C)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="98.77"
                     /coverage="100.0"
     gene            complement(9215..9274)
                     /gene="ermCL"
                     /locus_tag="HK402_RS14555"
                     /old_locus_tag="HK402_14570"
     CDS             complement(9215..9274)
                     /gene="ermCL"
                     /locus_tag="HK402_RS14555"
                     /old_locus_tag="HK402_14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="WP_002497446.1"
                     /translation="MGIFSIFVISTVHYQPNKK"
                     /name="ermCL"
     gene            9388..10062
                     /locus_tag="HK402_RS14560"
                     /old_locus_tag="HK402_14575"
     CDS             9388..10062
                     /locus_tag="HK402_RS14560"
                     /old_locus_tag="HK402_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_014158489.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYASILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKHTLKGIECIYALYKKNRRSLQIYGFLPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(10094..10357)
                     /locus_tag="HK402_RS14565"
                     /old_locus_tag="HK402_14580"
     CDS             complement(10094..10357)
                     /locus_tag="HK402_RS14565"
                     /old_locus_tag="HK402_14580"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_031590646.1"
                     /translation="MENEKTRNKKPYIYGFLLLIIILIALIIVFVVRKTDALGQINKFE
                     DAVESNDSKKVSEILSGSERTMSDKESKAFIKYMVLLQSKKI"
                     /name="hypothetical protein"
     gene            10824..11996
                     /locus_tag="HK402_RS14570"
                     /old_locus_tag="HK402_14585"
     CDS             10824..11996
                     /locus_tag="HK402_RS14570"
                     /old_locus_tag="HK402_14585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="WP_113805443.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKGDVSKNILTTVFNQLMENQRTEY
                     IQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALM
                     ASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPY
                     LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKER
                     GLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGI
                     FKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
                     /name="IS256-like element IS256 family transposase"
     gene            complement(12126..13565)
                     /gene="aph(2'')-Ia"
                     /locus_tag="HK402_RS14575"
                     /old_locus_tag="HK402_14590"
     CDS             complement(12126..13565)
                     /gene="aph(2'')-Ia"
                     /locus_tag="HK402_RS14575"
                     /old_locus_tag="HK402_14590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="WP_001028144.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
                     /name="aph(2'')-Ia"
     gene            complement(13566..13958)
                     /locus_tag="HK402_RS14580"
                     /old_locus_tag="HK402_14595"
     CDS             complement(13566..13958)
                     /locus_tag="HK402_RS14580"
                     /old_locus_tag="HK402_14595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000393259.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYT
                     LLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACH
                     VYEKLGGKNDYKDEIVYVYDYEKGDK"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(14015..15187)
                     /locus_tag="HK402_RS14585"
                     /old_locus_tag="HK402_14600"
     CDS             complement(14015..15187)
                     /locus_tag="HK402_RS14585"
                     /old_locus_tag="HK402_14600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="WP_000195429.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEY
                     IQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALM
                     ASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPY
                     LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKER
                     GLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGI
                     FKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
                     /name="IS256-like element IS256 family transposase"
     gene            complement(15265..15765)
                     /locus_tag="HK402_RS14590"
                     /old_locus_tag="HK402_14605"
     CDS             complement(15265..15765)
                     /locus_tag="HK402_RS14590"
                     /old_locus_tag="HK402_14605"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050439888.1"
                     /translation="MSKSGDFREYPKILKIENDGRIIALDKHGRVNSQFYTNTITDEDS
                     IKVFGLKFKLLYHDYVNDNLSRVEKNKDSYNENISTRNRPEDYYNERDFRRDLEQQQEN
                     TKAKRKNKWLVAVIVVLLIGLVILLFKSCSNGNEQQPTDNNDTSQEQIDNGQSNNDKVR
                     IIV"
                     /name="hypothetical protein"
     gene            complement(15787..16416)
                     /locus_tag="HK402_RS14595"
                     /old_locus_tag="HK402_14610"
     CDS             complement(15787..16416)
                     /locus_tag="HK402_RS14595"
                     /old_locus_tag="HK402_14610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449168.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_031588345.1"
                     /translation="MKIGYARVSSKNQNLDRQIEVLKANGAEKIFTEKQSGKNIKERPV
                     FQEVMNFVREEDTLIVDALDRLGRNYDEVIKTVDFLKEKNVRLIITSLPMMNEIIGNEL
                     LDKFLKNLIIQLLAMISEQERNDSRRRQADGIAVAKSKGIYKGRPKLYSPIAKDPHKQA
                     VYYRVVSFLDQGMAISKIAKKVGLSRQTIYRIKKDYQSGIYKDIDN"
                     /name="recombinase family protein"
     gene            complement(16645..18024)
                     /locus_tag="HK402_RS14600"
                     /old_locus_tag="HK402_14615"
     CDS             complement(16645..18024)
                     /locus_tag="HK402_RS14600"
                     /old_locus_tag="HK402_14615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002455970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(63)"
                     /protein_id="WP_050437591.1"
                     /translation="MNYINNKIKSLSYNILFWLCILSFFSVLNEMVLNVSLPDIAISFN
                     TSPAITNWVNTAYMLTFSIGTAVYGKLSDQVSIKKLLILGIILSCLGSLIGFFGHKHFL
                     ILILGRLIQGIGSAAFPSLVMVVVSRNITKAKQGKAFGFIGSIVALGEGIGPSIGGVVT
                     HYIHWSYLLIIPIFTLITIPFLNKIMEPGESQKGDLDILGILLMSISIISFMLFTTSYK
                     WFYLITFVIFFIIFIKHIVKVTHPFIDPALRKNPSFIFGLISGALIFATVAGFISMVPY
                     MMKALYHINAATIGNNVILPGTISVIIFGYIGGYLVDKKGALFVFVIGSLFISISFLVI
                     AFFVELNLWVTTISFIFVMGGLSFTKTVISTIVSSSLSHEEVGSGMSLLNFTSFLSEGT
                     GIIIMGGLLSTQFLNYNFLSEFITFSTNLYSNILIGCTIIIALCCLLTFILFNRTVKQH
                     T"
                     /name="tetracycline efflux MFS transporter Tet(63)"
     gene            complement(18244..19389)
                     /locus_tag="HK402_RS14605"
                     /old_locus_tag="HK402_14620"
     CDS             complement(18244..19389)
                     /locus_tag="HK402_RS14605"
                     /old_locus_tag="HK402_14620"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467322.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="WP_170172426.1"
                     /translation="MTNELKNVPELRFPEFEGEWENSKLGTVANVYDGTHQTPKYTSEG
                     IKFLSVENIKTLNSNKFISKEAFEKEFKIRPEFGDVLMTRIGDVGTPNVVETNEYLAYY
                     VSLALLKPKKLNSYFLESLIRSQSVQNELWRKTLHIAFPKKINKNEIAKVEINYPEQQE
                     QQKIGEFFSKLDRQIELEEQKLAKLEEQKKGYMQKIFSQELRFKDENGNDYPEWEIKKL
                     MQIAKVKTGSKNVQDNIQDGKFKFFDRSVEVKYLNTFDFDETAIIYPGEGSKFLPRYFS
                     GKYSLHQRAYSIYDININNNYLYYYLSLQNNHFLKYAVGSTVKSLRMSGFDKLKVMVPK
                     NSEQEKIGDFFNELDELIEKQSSKIGVLKQRKKGFLQKMFV"
                     /name="restriction endonuclease subunit S"
     gene            complement(19382..20938)
                     /locus_tag="HK402_RS14610"
                     /old_locus_tag="HK402_14625"
     CDS             complement(19382..20938)
                     /locus_tag="HK402_RS14610"
                     /old_locus_tag="HK402_14625"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002469809.1"
                     /GO_function="GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA]; GO:0009007 -
                     site-specific DNA-methyltransferase (adenine-specific)
                     activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M"
                     /protein_id="WP_170172427.1"
                     /translation="MSITEKQRQQQAELQKNLWSIADDLRGNMDANEFKNYILGMIFYR
                     FLSEKIEEQAQILLAEDNIDYETAMADEDYRPVLEQEFISRIGYVIEPQYLFGHLVKKI
                     EKQAFEMEDLSNAIKNIENSTRGHDSEDDFIHLFDDLDLNSSRLGNSNAARTKLISKVM
                     MKISTLPFVHSDMEIDMLGDAYEYLIGQFAASSGKKAGEFYTPQQVSTILAKIVTANKK
                     DIKSVYDPTCGSGSLLLRVGREANVRQYYGQEYNSTTYNLARMNMLLHDVNYANFKIEN
                     GDTIEDPAISDERFEAVVANPPYSAKWSSDPQFLEDPRFSNYGKLAPKSKADFAFIQHM
                     IYHLDDNGTMAVVLPHGVLFRGAAEGVIRQYLIKEKNYLDAIIGLPSNLFFGTSIPTSI
                     LVFKKCREADDNVLFIDASQSFEKGKNQNHLTTEDVEKIVETYKNRETLDKYSYAASLE
                     EIAENDYNLNIPRYVDTFEEEEPIDLEQVQKDLNSIDDEIKAVEQEIEGFLKELGVVTH
                     D"
                     /name="type I restriction-modification system subunit M"
     gene            complement(20939..21514)
                     /locus_tag="HK402_RS14615"
                     /old_locus_tag="HK402_14630"
     CDS             complement(20939..21514)
                     /locus_tag="HK402_RS14615"
                     /old_locus_tag="HK402_14630"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508614.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="WP_107643531.1"
                     /translation="MLKDYVNYQSGTLIQRLEVDESDLGNRYMVYDQNMLDIDLGLTID
                     DTYQPRVIKLKDTSRATVVRKDDIVLSMMTGECTLVSSRHDGSILPYNYTKIEVTSDLL
                     EPAFLVYWFQLAPEVQSQYKQYMQGGSTIKKLTHQQLKSLYITLPSIERQRLIGQIGIK
                     EKQLNVLKQRQSRLKKQFLSNTLFKEDN"
                     /name="restriction endonuclease subunit S"
     gene            complement(21611..24397)
                     /locus_tag="HK402_RS14620"
                     /old_locus_tag="HK402_14635"
     CDS             complement(21611..24397)
                     /locus_tag="HK402_RS14620"
                     /old_locus_tag="HK402_14635"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002512569.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0003677 - DNA binding [Evidence IEA]; GO:0004386 -
                     helicase activity [Evidence IEA]; GO:0009035 - type I
                     site-specific deoxyribonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="WP_170172428.1"
                     /translation="MGYQSEYGLEENVIKQLQDLGYERVLLRNETQLKENFRRILNERN
                     ADKLEGTPISDSEFKRIMIDISDKSVFESAQILRDKYVLERDDETKVYLSLMNIKKWCQ
                     NTFQVTNQVSVNDTHKSRYDVTVLINGLPLVQIELKRSGVAITEAFNQIERYRRQNYTG
                     LFRFIQMFVVSNKMETRYYANSDQKIMKSHMFYWSDEKNERINVLKDFIESFLEPCHIA
                     KMISRYMIINETDKILMALRPYQVYAVEALLNRAIETNNNGYIWHTTGSGKTLTSFKAS
                     QILAQEPDIKKVIFLVDRKDLDGQTLGEFNKFESDSVDRTFNTKKLLKQMDDPTRKLIV
                     TTIQKMDNAIKSGHPAMERYKEDKVVFIIDECHRTQFGSMHRIIRQHFGNAQYFGFTGT
                     PRFEENASQDGRATADIFGECLHHYLIKDAIRDGNVLGFSVEYMNTFDRSEKIIEDGYV
                     NKINEAEIWMADERVQKVAEHIIANHNKKTRDQMYTGMLTVQSIPMAIQYYRVFQKLKK
                     QGVHNLNVTTIFSYQDNEAIDDTMDEQTRRDILEGIIQTYNETFDKNFSTDTFDGYFND
                     VSNRVKKGLPNQKLDILIVVDMFLTGFDSKKLNTLYVDRNLQHHTLIQAYSRTNRVEEP
                     TKPYGNIVAYRNLKEKTDEAIELFSKTDNTDTVLSLSFQAYLTKFKQALIELFELAETP
                     QAVDQLEREEDQRDFVIAYRELAKHMQKLKTFDEFAFDKEMLGIDEQTYEDYKGKYLDI
                     YDKVMRPDKETLEGESILDNIDFNIEILRNDLINVQYILDLLNQIDLSDTEQQEKDIKE
                     IRKVLDKADDDQLRLKSDLIRTFLDKVVPNLNEGDSIDDAYYNYESKVKVGELEQFSEE
                     TDYPLELLKSLVKEFEFSGHLNNNLIEEGVSGGLLIRTKKIKRVKSFIKDMVKKYSV"
                     /name="type I restriction endonuclease subunit R"
     gene            complement(24534..25238)
                     /locus_tag="HK402_RS14625"
                     /old_locus_tag="HK402_14640"
     CDS             complement(24534..25238)
                     /locus_tag="HK402_RS14625"
                     /old_locus_tag="HK402_14640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_170172429.1"
                     /translation="MKSVKMLSEELKVSKQTIFNNIKRLNIETIKQENTSFIKDDTDIE
                     RIIQRVNENKKKYGFESNTADIKNNESDNVESENDAQIIEILKHQIDTLNRQIEKQESR
                     HETTLEFYRKELQERSKLLENQQILALESNKKIQKLENQLEEERHLNYPLDTSNNDRKN
                     VDVQETTDTTNSVNINQDQESEMQYEDISERQSHESTQDDLSNSNDNDSDIEEKSEETQ
                     QKKGFWNRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             complement(16649..18024)
                     /name="tet(63)"
                     /gene="tet(63)"
                     /gene_name="tetracycline efflux MFS transporter Tet(63)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(12130..13565)
                     /name="aac(6')-Ie/aph(2'')-Ia"
                     /gene="aac(6')-Ie/aph(2'')-Ia"
                     /gene_name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             6574..7343
                     /name="ANT(4')-Ia"
                     /gene="ANT(4')-Ia"
                     /gene_name="ANT(4')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.21"
                     /coverage="101.19"
     ARG             complement(12127..13565)
                     /name="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene_name="aminoglycoside bifunctional resistance protein"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(8424..9157)
                     /name="ErmC"
                     /gene="ErmC"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="97.95"
                     /coverage="100.0"
     Typing          1092..1279
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="97.884"
                     /coverage="100.0"
                     /evalue="2.17e-87"
     Typing          5410..6413
                     /name="rep_cluster_1018"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(24535..25238)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="81.745"
                     /coverage="100.0"
                     /evalue="5.19e-164"
ORIGIN
        1 atgtcaaatt ttaaaagaat tacaatacaa gaatttgaac aagaaagatt ttataaacta
       61 tataaatttt tatttgaaga tgattatttt agaaagctta gtgactctgc aaaaattgct
      121 tactgtatat ttagagaccg attcgaatta tctaaaataa ataattggat tgatcaaaat
      181 ggcaatgtat atttaatatt tactactaaa gatttatgta atcttttaaa ttgtggaact
      241 caaaaagtaa ctaaaattaa aaaagaatta gaaagtttta atcttttaga acaagaaaga
      301 atggggttaa acaaaccaaa taaaatatat atactagagc ccaaaaaacc atctaaactt
      361 aatgatatca aggaatttcg aaaatcaaaa ttccagagtg atgaaaatca aaattctgga
      421 attttgaaag tcaaaaaaca agaatttcga aaatcaaaat caaatgatac taatttaaat
      481 aatactgatt atatagagac tgagcataat gatatgaatg acctgaatga tacctacaac
      541 aatatttcaa tagaccatac tcattcaaat cagccaaatc aatttttaaa taactttggt
      601 aatcaagatg ataaagaaat actactccaa gagttcccag atcaacttac gtcttattta
      661 ttaaattaca gttatacaga tttagaaatt ataaaaagtg taattcttaa agctaaaaaa
      721 tcatttaatt caaaccatga tgatacttac tacatgttag aacatattga agatgaaata
      781 ttaatagctt taaaaagagt aaaaaaagcg atacatgata gaggggttaa aggccaaaag
      841 gaaacgatca gttcgatgca agggtactta atgcgaacaa ttttaagtga acttgaagaa
      901 agctattcag tcgatatgag aagacaaaat atggcgaaat ataatatttt taatcagtaa
      961 attaaataag cttgcagcaa tcaaagaaac ctcgaaatat tcggttaaat catctgattt
     1021 tttaactgat gatgacgaaa gaaatcagga aatcgtgaat gatttagaaa aaggtttata
     1081 ccgaaaacgt atgttgagtt atggtggatt gcttaaacaa aaacataaaa ttttaaattt
     1141 agacgatgcc gaagatggca atttaattaa tacaagtgac gaagataaaa caacagacga
     1201 agaagaaaaa gcacattcaa ttactgcaat ttggaatttt gaaaaacaaa attattactt
     1261 aaaagatttg aaacgttagc ttaaaagcta gcgttttttt atgtattttt gcccctgcag
     1321 gaactatagc gttcaaccgg catggttgac cagttttacc atgaaaattt taatttgcat
     1381 gtaaatgggc cagtgtctga aaaattcgcc actggttttg atcaaatttt agtttgtaga
     1441 attagaatat atttattcgg ctcatatttg cgttttaaaa gcttatgtag gtttttaggt
     1501 ataaaactat atgttttatg cctaaatctt taaaataccc ccttaaaatt caaaataagg
     1561 gtatttaatt ttttaataag tcttgtgata aagttttgcc aaaaaggaga tagaaaatgc
     1621 ttatattttt atttattttg atttgtggtc ttttaggtta tttcttgatt aatcgttcta
     1681 gaaaaaagta gacgacgcat ttatgccgag aaaatttatt gaagttgaga agaaccctta
     1741 actaaacttg cagacgaatg tcggcatagc gtgagctatt aagccgacca ttcgacaagt
     1801 tttgggattg ttaggggttc cgaggctcaa cgtcaataaa gcaattaagt atatgaaaaa
     1861 ttgttttggg tatgttatat tttaatagtt aggcgcctaa ctaaatgtgg ggagtgttct
     1921 ttttggatga attttattta attgatagtc cgtcttttga gaagttgaag gatttaaaaa
     1981 atgaatatag taatttggat attacttcag ttttacttta tttagaaatt caaaaagcgt
     2041 ataaaaaaat gaaattgaac catgatgtgt ttttacagaa attcgattta tctgaatcta
     2101 aattcacaat catgatgtta ttatcttatg aaaaagatat gacgttatct ccttcaaatt
     2161 tgtctgaaaa aataggtagc aagaaatcta ctataacagg agttttaaag ggtttagaga
     2221 aaaacgggtt agttgaaaga gaagttttat ctcatgataa gaggacaaat tatgttcaat
     2281 taacagattt ggggttgagg aaattaaaag aatttttgcc ttataactat gaagttgttt
     2341 caaaggtttt tgaagttttt agcgaacaag aaaaagaaga attttataga ttagcgaata
     2401 aacttaaaaa taatttagaa aaggatgatc tattttgaat aaagtagaat ttttagaaac
     2461 gtttctaagt ctttatatta atcatcatga agttcttaaa gatatggaaa acggaacagg
     2521 caaatatgta attattgatg ttcgaaacgc acctaaaaaa gttaaaaaag ataaaattaa
     2581 gaattctgtt gaaatacctg ctaaggattt aaaaaatcat ttatctagtt tagataaaga
     2641 taaaatatat gtagtttatg attggactgg cggtactatt ttaggtaagg cagctttatt
     2701 agatttttat aggaatggat ttgaagcata tgaattagct ggggctttag aaggttggaa
     2761 aggtatgagt ttgcctttag aagatgttga gtagtttctt tattagattc cttttcattt
     2821 agaaaaagga atcttttttt gaaacgagtt tcttcttgtc ttgagtctta tttagctcat
     2881 atttgcgttg taaggtttaa aaaaataaaa agcgttattt tgagtaaggg aaaaataaac
     2941 atgcttaaaa taccccctta aaattcaaaa taaaagtatg cataaaaatg tatattttga
     3001 aaaaataacg cagatttgag aatttaaaat tgaaattggg aaatcttgga gaagttataa
     3061 ttttataatc gccgatataa aagtcttgta aagaatctga atacaagttc tgacgatgcc
     3121 aggaaacttt tatacaggtt atacatttta aaattggaat atgtgtctta ggcgtatgat
     3181 ctgtttggtt ttaacatggc ttaaaagaga tgtataaagc ataagaagac acctcagcta
     3241 tgctgagtga cacgtagtgg cattgtgtcc ccttatgctc ttatcaggga gtctaaaagg
     3301 agtcgctgat ataattaata ggtaagaata aacaatgtaa gttgttctat taattaccgt
     3361 taatataatg ttataagttt tatattaata aactttaatc atcttaattg agttcgttta
     3421 ttaataaatc aaataaccac atttttattt ttgatttatt aaatgcaatt aaacttagtt
     3481 ataagttaat gcaagaggtt tagtttttga aatactaatt aaatgttata aaaaagagga
     3541 atctatacat aatataaatt cctctaaaga tatttgaata tactttatta acttaatgca
     3601 tcttttatat cacttgtagg taaaagagaa ctatattaat agttccctaa ataatttcat
     3661 caatccgttt catttgtttt aataaatcat ttttaaaatt aacaatcata tatgagttga
     3721 aaccactttt tatttttccg aatatagcat atggttctgt tatatttatt ttatccaacc
     3781 aatttagtaa taatatataa tcaaatacat caatatgatt aattaatatt tcatatctta
     3841 aatttcgatt tattatttag taataaagac caaaaaataa ccatctagag catactttga
     3901 cgagtaacta gaggttattt taatagtaat ttaagttata agtcaccgtc tttttaacgg
     3961 gctcattagg gtagcataca ttagtatgtt gtcctttttc tatataaatt aataataacg
     4021 ttgtattaca taaatcccaa tatgctattt taatatataa cccataacta aaaattagct
     4081 gcttttattc ataatgtgac catgcagaaa ggataaaaac ttccttatca tcttcatcaa
     4141 ctgtgtaaac aactctatgt tgatggttta tccttcttga atagcgccct aagtgtttag
     4201 gttgcaactt ttcaaaagac tggttcggaa aataagggtc ttcttttaac gtgtctacaa
     4261 tttttaagaa ttgtgttttc aactgcgatt gtttaatttt ctttaaatca gattttgctg
     4321 aatttttaat agaaatactg taattatcca tttagaggtt gtcccagtct atatcatcaa
     4381 tattagtgta gccactgtta tccttttcac gctctcgtac tttatccata gtccctgtgg
     4441 tttcaagata taatgtttct tgaatactat cccaatcttt ttggcttata attacggcgt
     4501 tattttcact cttagaactg cttataataa cgggttcgtg gctatcatta acttgtttaa
     4561 gtagttcata gaattctttt ctagcattag taggcgtttt aatattcatt attagtcacg
     4621 tcctttcttt atcctatatt ataacgtact taaaaacgta cgtaaagtta tgacctataa
     4681 tggattataa gtttgatttt tacataattc aacttatcgg aagtagatat gtttgtacat
     4741 tcacagatga tataataatg gagtcgcctt aacttccata ggcgaaatta ctatggaagg
     4801 aggtgagacc tatggcaatt ctctttgtta gtataattgc acctgtgatt tcaggatgca
     4861 ttgttgcgat tttcacgttt tggctaaaca atcgtaacaa gtaataaggc gacatagctg
     4921 caccaaaaaa tcccctcact accggaaata gtgaggggat tggtgtacct atggaactct
     4981 ctttgttaaa tacagtataa catcatatat ggtaagaatg caaaagtaat taaaaagtga
     5041 ttttaagtta tcattattaa ctcttaatta aattcttttt taaaagaatc taattttttt
     5101 aagtcgcctt gcatttcttc taatgaaggt atcattcttc ctatagctgg agattcatca
     5161 tggaccatag ctgaagattt tgtcatgcct tcggttacca tttgtattaa atggtcatta
     5221 attttaactt ttcgtaattc ttgagtcttg atacatatag aaataacgtc atttttattt
     5281 tagttgctga aaggtgcgtt gaagtgttgg tatgtatgtg ttttaaagta ttgaaaaccc
     5341 ttaaaattgg ttgcacagaa aaaccccatc tgttaaagtt ataagtgacc aaacaaataa
     5401 ctaaatagat gggggtttct tttaatatta tgtgtcctaa tagtagcatt tattcagatg
     5461 aaaaatcaag ggttttagtg gacaagacaa aaagtggaaa agtgagacca tggagagaaa
     5521 agaaaatcgc taatgttgat tactttgaac ttctgcatat tcttgaattt aaaaaggctg
     5581 aaagagtaaa agattgtgct gaaatattag agtataaaca aaatcgtgaa acaggcgaaa
     5641 gaaagttgta tcgagtgtgg ttttgtaaat ccaggctttg tccaatgtgc aactggagga
     5701 gagcaatgaa acatggcatt cagtcacaaa aggttgttgc tgaagttatt aaacaaaagc
     5761 caacagttcg ttggttgttt ctcacattaa cagttaaaaa tgtttatgat ggcgaagaat
     5821 taaataagag tttgtcagat atggctcaag gatttcgccg aatgatgcaa tataaaaaaa
     5881 ttaataaaaa tcttgttggt tttatgcgtg caacggaagt gacaataaat aataaagata
     5941 attcttataa tcagcacatg catgtattgg tatgtgtgga accaacttat tttaagaata
     6001 cagaaaacta cgtgaatcaa aaacaatgga ttcaattttg gaaaaaggca atgaaattag
     6061 actatgatcc aaatgtaaaa gttcaaatga ttcgaccgaa aaataaatat aaatcggata
     6121 tacaatcggc aattgacgaa actgcaaaat atcctgtaaa ggatacggat tttatgaccg
     6181 atgatgaaga aaagaatttg aaacgtttgt ctgatttgga ggaaggttta caccgtaaaa
     6241 ggttaatctc ctatggtggt ttgttaaaag aaatacataa aaaattaaac cttgatgaca
     6301 cagaagaagg cgatttgatt catacagatg atgacgaaaa agccgatgaa gatggatttt
     6361 ctattattgc aatgtggaat tgggaacgga aaaattattt tattaaagag tagttcaaca
     6421 aacgggccag tttgttgaag attatatgct ataattgtta ttaaaaggat tgaaggatgc
     6481 ttaggaagac gagttattaa tagctgaata agaacggtgc tctccaaata ttcttattta
     6541 gaaaagcaaa tctaaaatta tctgaaaagg gaatgagaat agtgaatgga ccaataataa
     6601 tgactagaga agaaagaatg aagattgttc atgaaattaa ggaacgaata ttggataaat
     6661 atggggatga tgttaaggct attggtgttt atggctctct tggtcgtcag actgatgggc
     6721 cctattcgga tattgagatg atgtgtgtca tgtcaacaga ggaagcagag ttcagccatg
     6781 aatggacaac cggtgagtgg aaggtggaag tgaattttga tagcgaagag attctactag
     6841 attatgcatc tcaggtggaa tcagattggc cgcttacaca tggtcaattt ttctctattt
     6901 tgccgattta tgattcaggt ggatacttag agaaagtgta tcaaactgct aaatcggtag
     6961 aagcccaaac gttccacgat gcgatttgtg cccttatcgt agaagagctg tttgaatatg
     7021 caggcaaatg gcgtaatatt cgtgtgcaag gaccgacaac atttctacca tccttgactg
     7081 tacaggtagc aatggcaggt gccatgttga ttggtctgca tcatcgcatc tgttatacga
     7141 cgagcgcttc ggtcttaact gaagcagtta agcaatcaga tcttccttca ggttatgacc
     7201 atctgtgcca gttcgtaatg tctggtcaac tttccgactc tgagaaactt ctggaatcgc
     7261 tagagaattt ctggaatggg attcaggagt ggacagaacg acacggatat atagtggatg
     7321 tgtcaaaacg cataccattt tgaacgatga cctctaataa ttgttaatca tgttggttac
     7381 gtatttatta acttctccta gtattagtaa ttatcatggc tgtcatggcg cattaacgga
     7441 ataaagggtg tgcttaaatc gggccatttt gcgtaataag aaaaaggatt aattatgagc
     7501 gaattgaatt aataataagg taatagattt acattagaaa atgaaagggg attttatgcg
     7561 tgagaatgtt acagtctatc ccggcattgc cagtcgggga tattaaaaag agggttctgt
     7621 tgcaaagttg aatttatagt ataattttaa caaaaaggag tcttctgtat gaactatttc
     7681 agatataaac aatttaacaa ggatgttatc actgtagccg ttggctacta tctaagatat
     7741 gcattgagtt atcgtgatat atctgaaata ttaagggaac gtggtgtaaa cgttcatcat
     7801 tcaacggtct accgttgggt tcaagaatat gccccaattt tatatcaaat ttggaagaaa
     7861 aagcataaaa aagcttatta caaatggcgt attgatgaga cgtacatcaa aataaaagga
     7921 aaatggagtt atttatatcg tgccattgat gcagagggac atacattaga tatttggttg
     7981 cgtaagcaac gagataatca ttcagcatat gcgtttatca aacgtctcat taaacaattt
     8041 ggtaaacctc aaaaggtaat tacagatcag gcaccttcaa cgaaggtagc aatggctaaa
     8101 gtaattaaag cttttaaact taaacctgac tgtcattgta catcgaaata tctgaataac
     8161 ctcattgagc aagatcaccg tcatattaaa gtaagaaaga caaggtatca aagtatcaat
     8221 acagcaaagc atactttaaa aggtattgaa tgtatttacg ctctatataa aaagaaccgc
     8281 aggtctcttc agatctacgg atttttgcca tgccacgaaa ttagcatcat gctagcaagt
     8341 taagcgaaca ctgacatgat aaattagtgg ttagctatat ttttttactt tgcaacagaa
     8401 cccagtttat gcatccctta acttacttat taaataattt atagctattg aaaagagata
     8461 agaattgttc aaagctaata ttgtttaaat cgtcaattcc tgcatgtttt aaggaattgt
     8521 taaattgatt ttttgtaaat attttcttgt attctttgtt aacccatttc ataacgaaat
     8581 aattatactt ctgtttatct ttgtgtgata ttcttgattt ttttctattt aatctgataa
     8641 gtgagctatt cactttaggt ttaggatgaa aatattctct tggaaccata cttaatatag
     8701 aaatatcaac ttctgccatt aaaagtaatg ccaatgagcg ttttgtattt aataatcttt
     8761 tagcaaaccc gtattccacg attaaataaa tctcattagc tatactatca aaaacaattt
     8821 tgcgtattat atccgtactt atgttataag gtatattacc aaatatttta taggattggt
     8881 ttttaggaaa tttaaactgc aatatatcct tgttaaaaac ttgaaaatta tcgtgatcaa
     8941 caagtttatg ttctgtagtt ttgcataatt tatggtctat ttcaatggca gttacgaaat
     9001 tacacctttg tactaattca agggtaaaat ggccttttcc tgagccgatt tcaaagatat
     9061 tatcatgttc atttaatctt atatttgtca ttattttatc tatattatgt ttcgaagtaa
     9121 taaagttttg actgtgtttt atatttttct cgttcattat aaccctcttt aatttggtaa
     9181 tgaattttgc ttattaacga ttcattataa ccacttattt tttgtttggt tgataatgaa
     9241 ctgtgctgat tacaaaaata ctaaaaatgc ccatattttt tcctccttat aaaattagta
     9301 taattatagc acgagctctg ataaatatga aggttctgtt gcaaagttga atttatagta
     9361 taattttaac aaaaaggagt cttctgtatg aactatttca gatataaaca atttaacaag
     9421 gatgttatca ctgtagccgt tggctactat ctaagatatg cattgagtta tcgtgatata
     9481 tctgaaatat taagggaacg tggtgtaaac gttcatcatt caacggtcta ccgttgggtt
     9541 caagaatatg cctcaatttt atatcaaatt tggaagaaaa agcataaaaa agcttattac
     9601 aaatggcgta ttgatgagac gtacatcaaa ataaaaggaa aatggagtta tttatatcgt
     9661 gccattgatg cagagggaca tacattagat atttggttgc gtaagcaacg agataatcat
     9721 tcagcatatg cgtttatcaa acgtctcatt aaacaatttg gtaaacctca aaaggtaatt
     9781 acagatcagg caccttcaac gaaggtagca atggctaaag taattaaagc ttttaaactt
     9841 aaacctgact gtcattgtac atcgaaatat ctgaataacc tcattgagca agatcaccgt
     9901 catattaaag taagaaagac aaggtatcaa agtatcaata cagcaaagca tactttaaaa
     9961 ggtattgaat gtatttacgc tctatataaa aagaaccgca ggtctcttca gatctacgga
    10021 tttttgccat gccacgaaat tagcatcatg ctagcaagtt aagcgaacac tgacatgata
    10081 aattagtggt tagctatatt tttttacttt gcaacagaac catatatttt ataaacgctt
    10141 ttgattcctt gtctgacata gtccgttcac taccggataa aatttcactg acttttttag
    10201 aatcattaga ttctacagca tcttcaaatt tatttatttg tcctagggca tctgtttttc
    10261 taactacaaa tacaattatt aaagcaatta agataattat tagtaataag aaaccatata
    10321 tatatggctt cttattacgt gtcttttcat tttccatacg cattaccctt tatatcaatg
    10381 tagtagcaag ttatttatta ctattaaacc acgatgaaat tttattcttg atttcatcta
    10441 acttattatt aactttattt aattcttctt ccattttttc attgttacca ttatcttgtt
    10501 gggtttttgc gtctttcaaa ttattaattg tgttctgata atcttctgca actttattta
    10561 atttgtctgt atctgcttgt tgttttaggc tatcaacttt attttgtaat tctgcaattt
    10621 ttgaatttgt atcatcattg ctattctcaa tactatcttt tgtagattga atttgatcac
    10681 gaatttcttg gtcttgttct tctacttttt ggccattatt tggataaagt ccgtataatt
    10741 gtgtaaaagt aaaaaggcca tataacagtc cttttacggt acaatgtttt taacgacaaa
    10801 aacataccca ggaggacttt tacatgaccc aagtacattt tacactgaaa agcgaagaga
    10861 ttcaaagcat tattgaatat tctgtaaagg gtgacgtttc taaaaatatt ttaacaacgg
    10921 tatttaatca actaatggaa aatcaacgaa cagaatatat tcaagcaaaa gaatatgaac
    10981 gaacagaaaa ccgacaaagt caacgaaatg gctattatga gcgcagcttt acgacacgtg
    11041 taggcacgct agaattaaaa gtacccagaa cacgtgatgg ccatttttca cccacagtgt
    11101 ttgaacgtta tcaacgaaac gaaaaagccc tcatggcttc aatgttggaa atgtatgtat
    11161 caggcgtttc aactcgtaaa gtatcaaaaa ttgtggaaga actttgtggt aaatccgtct
    11221 ctaagtcctt cgtttctagc ttaacagaac agctagaacc tatggttaac gagtggcaga
    11281 atcgtttatt atcagaaaaa aattatcctt acttaatgac cgatgtactc tatataaaag
    11341 tacgagaaga aaatcgagta ctctcaaaaa gctgtcatat agcgattgga ataaccaaag
    11401 atggcgaccg tgaaattatc ggcttcatga ttcaaagtgg cgaaagcgaa gagacctgga
    11461 caacattttt tgaataccta aaagaacgcg gtttacaagg tacggaactc gttatttctg
    11521 atgcgcacaa aggattagtc tctgccatta gaaaatcctt caccaacgta agttggcaaa
    11581 gatgccaagt tcacttccta agaaatatct ttaccaccat tcctaaaaaa aattcaaaat
    11641 ctttcagaga agctgttaaa ggaattttta agttcacaga tattaactta gcgcgtgagg
    11701 ctaaaaatcg attgattcat gattatatcg atcaaccaaa atattcaaaa gcttgcgcat
    11761 cattggatga tggattcgaa gacgcctttc aatataccgt acaaggaaat tcccacaatc
    11821 gactaaagag taccaatcta attgaacgac tgaatcaaga agtacgcaga agagaaaaga
    11881 ttattcgcat cttccccaat caaacatcag ccaatcgctt aattggagcc gttcttatgg
    11941 acctacatga tgaatggatt tattcttcaa gaaaatacat caattttgat aagtagaaat
    12001 ggtaaaaaca ttgtatagca ttttacacag gagtctggac ttgactcact tcctttatta
    12061 tttttcattt ttttaaacta tttaatacta atgtctttta taatagcttt tcatatatta
    12121 tataatcaat ctttataagt ccttttataa atttcttttc taccattttc gataaattcc
    12181 tgtttaatat ttttaattcc ataaacaata gtttcaatag gataatattc ttcaactata
    12241 tcttgatatt cttttgcttt ctcaatatct atatttccat acattcttaa tatatcttct
    12301 ccaaaatttg ttcctatttc ttcttcacta tcttcaagta agtatataaa atcacaatat
    12361 tcatctataa ttccagaatc tccaaaatca attattccag ttaatctatt attgccatct
    12421 aacaatagat gattacaact aaaatcatta tggcataaac actttttacc ctcaaaaact
    12481 gttgttgcat ttagtctttc cataaaactt tctatataat ctttttctat atcagttaaa
    12541 tcattataaa tagtttcacg caacaatata tactcttcta atacattttg tttattatca
    12601 atagtacatt cactaatatc tgtataatct aaaccgtgca tttgtcttaa aaaactggca
    12661 atatctcgtt ttaacaaatt ttgttcttct tctgacatag tagaataaat ttctggtgtt
    12721 aaaaaagttc ctttaatttc tttataacct agtatagata attcatcact aatatacgaa
    12781 tattcaatat taggaatttt tacattagtt tctaaatttg tatttaaaaa attatatatt
    12841 gctttttctt ttgcataacc ttttttctta ttagtactaa attttgtttt aaaaatgtat
    12901 tcattattaa ctaaatatgc cacactatca taaccactac cgattatttc aatactatct
    12961 actttgaaat tatcaaagta atgctcaatt aaatatttca ttgccttaac atttgtggca
    13021 ttatcatcat atctatattc cattaaataa caatcttctt ttttgccctc gtgtaattca
    13081 tgttctggca aatcttcaat aattctaaaa ccagattttt ggtatgccct tattgctctt
    13141 ggattatttt tatgagggtc taaaataact gcattagcat ttctttcttt tttcaaaaat
    13201 tcaaaaatca atttaatata tcttgtacca attcctttac tccaataatt tggctctcct
    13261 ataaattgat ccataccata gactatctca tcagtttttg gataatgata atcagtatat
    13321 aactcatcat acattttata tatttgtcca tatccaatag gaacattgtt atattcaata
    13381 attactctaa aaacttcatc ttcccaaggc tctgtataat gtttttttaa tgattctaat
    13441 gtatattttt tatctctacc accataaaat tctaatactc tttcatcagt taaccatttt
    13501 aacatcaaag gaaaatcatc atctattaaa gttcttatac atatttcatt ttcaactata
    13561 ttcatttatt tatcaccttt ttcataatca tatacatata ctatttcatc tttataatca
    13621 tttttaccac ctaatttttc atatacatgg caagctctag gattaccttt atcagttatt
    13681 aaaaacattt cagaacaacc aatctcttta gaatattcct taataaaaga taataatttt
    13741 gaaccataac ctttgtcttg atagttaggt aacattccta ttgagtgtaa ataaaacatt
    13801 gtttttccat caggtcttaa aagtgtatag caatatgcaa atcctataat tttattattt
    13861 tctttagcta taaacccaaa tgaactggta tcattaagaa atccttttaa attatcaata
    13921 tcaaaaacca tattatcatc aattaaaact tcttccataa actcagtcaa gtccagactc
    13981 ctgtgtaaaa tgctatacaa tgtttttacc atttctactt atcaaaattg atgtattttc
    14041 ttgaagaata aatccattca tcatgtaggt ccataagaac ggctccaatt aagcgattgg
    14101 ctgatgtttg attggggaag atgcgaataa tcttttctct tctgcgtact tcttgattca
    14161 gtcgttcaat tagattggta ctctttagtc gattgtggga atttccttgt acggtatatt
    14221 gaaaggcgtc ttcgaatcca tcatccaatg atgcgcaagc ttttgaatat tttggttgat
    14281 cgatataatc atgaatcaat cgatttttag cctcacgcgc taagttaata tctgtgaact
    14341 taaaaattcc tttaacagct tctctgaaag attttgaatt ttttttagga atggtggtaa
    14401 agatatttct taggaagtga acttggcatc tttgccaact tacgttggtg aaggattttc
    14461 taatggcaga gactaatcct ttgtgcgcat cagaaataac gagttccgta ccttgtaaac
    14521 cgcgttcttt taggtattca aaaaatgttg tccaggtctc ttcgctttcg ccactttgaa
    14581 tcatgaagcc gataatttca cggtcgccat ctttggttat tccaatcgct atatgacagc
    14641 tttttgagag tactcgattt tcttctcgta cttttatata gagtacatcg gtcattaagt
    14701 aaggataatt tttttctgat aataaacgat tctgccactc gttaaccata ggttctagct
    14761 gttctgttaa gctagaaacg aaggacttag agacggattt accacaaagt tcttccacaa
    14821 tttttgatac tttacgagtt gaaacgcctg atacatacat ttccaacatt gaagccatga
    14881 gggctttttc gtttcgttga taacgttcaa acactgtggg tgaaaaatgg ccatcacgtg
    14941 ttctgggtac ttttaattct agcgtgccta cacgtgtcgt aaagctgcgc tcataatagc
    15001 catttcgttg actttgtcgg ttttctgttc gttcatattc ttttgcttga atatattctg
    15061 ttcgttgatt ttccattagt tgattaaata ccgttgttaa aatattttta gaaacgtcat
    15121 cctttacaga atattcaata atgctttgaa tctcttcgct tttcagtgta aaatgtactt
    15181 gggtcatgta aaagtcctcc tgggtatgtt tttgtcgtta aaaacattgt accgtaaaag
    15241 gactgttata tggccttttt acttttacac aattatacgg actttatcat tatttgattg
    15301 gccattatca atttgttctt gtgatgtatc attattatct gtaggttgtt gctcatttcc
    15361 attgctacat gatttaaaca acaatattac taaaccaatc aataatacta caatgactgc
    15421 tactaaccat ttattttttc ttttagcttt agtgttctct tgctgctgtt ctaaatcacg
    15481 tctaaaatca cgttcattat agtaatcttc cggtcgattt cttgttgata tattttcatt
    15541 atatgaatct ttattttttt caactctact taaattatca ttaacataat catgatataa
    15601 taatttaaat ttcaaaccga aaacttttat cgaatcttca tcagttattg tgtttgtata
    15661 aaattgactg tttactctac catgtttatc taaagcaatg attcttccat cattctctat
    15721 ttttaaaatt ttagggtact ctctgaaatc tcctgattta ctcataacga ttacctccat
    15781 aataaattaa ttatctatat ctttatatat tccactttga taatcttttt ttattctata
    15841 tatggtttgt cttgataatc ctactttttt agcaatttta ctaattgcca taccttgatc
    15901 taaaaaacta acaacacgat aatatactgc ctgtttatgt gggtctttag caataggact
    15961 atataatttg ggtcgccctt tatatatacc tttagatttt gcaacagcta ttccatcagc
    16021 ctgtctacgt ctgctatcat ttcgttcttg ttctgaaatc attgccagta attgaataat
    16081 taaatttttt aagaatttat ctaacaattc attaccgata atttcattca tcattggtag
    16141 gcttgtaatt attaatctaa catttttttc tttaagaaaa tctactgttt taattacttc
    16201 atcataattt ctgcctagcc tatctaatgc atcgactatt aaagtatctt cttctcgtac
    16261 aaaattcatt acttcttgaa atactggtct ttctttaata ttttttcctg attgtttttc
    16321 agtaaatatt ttttctgcac catttgcttt cagtacttca atttgtctat ctaaattctg
    16381 atttttagat gatactcggg cataaccaat tttcaaaatc tcaccacctt tttgttacac
    16441 cctaatcata caatttaaac cttaaaaaaa caacatttct cactgactga ttagggttta
    16501 ctctaaatca acaatacaca taataaaaca cctcacaaat aaatatgagg tgttttatat
    16561 ggttagaaag ataacgctat gctatttcct tatatcctat aaatttacta cgacagtaat
    16621 aacaatatat ttataatttt gagtttaagt gtgttgtttt actgtacgat taaataatat
    16681 aaatgttaac aaacaacaaa gtgcaattat aattgtacaa ccaataagga tattactgta
    16741 aaggttggtg gaaaaagtaa tgaattctga aaggaaatta taatttaaaa attgtgttga
    16801 tagtaatccg cccattatta taatgcctgt gccttctgat aaaaaactag taaaatttaa
    16861 taagctcata ccagaaccga cttcttcatg agaaaggcta ctagaaacta tcgttgatat
    16921 aacagttttt gtaaatgaaa gtcctcccat gacaaaaatg aaagagatgg ttgttaccca
    16981 caaatttaat tcaacaaaaa atgcaataac aagaaaacta atagatataa atagcgaacc
    17041 tataacaaag acaaacaaag cacctttttt atctactaag tatccaccaa tatatccaaa
    17101 tataataaca cttatagtac caggaagaat aacattgttc ccaattgtcg cggcgtttat
    17161 atggtaaaga gctttcatca tataaggaac cattgagata aatccggcta cagtagcaaa
    17221 tataagagct cctgaaatca atccaaaaat aaatgatggg ttcttccgca aagctgggtc
    17281 aataaaagga tgggtaactt ttacaatatg tttaataaaa atgataaaga aaataacaaa
    17341 ggttattaaa taaaaccatt tgtaacttgt tgtaaataac ataaagctta tgatacttat
    17401 agacattaaa aggatcccta atatatctaa atctcctttt tgagattcgc caggttccat
    17461 gattttatta agaaaaggaa tggttattaa tgtgaaaata ggtattataa gtaaatatga
    17521 ccaatgaata taatgagtta caacgcctcc tattgaaggc cctattcctt cacccaatgc
    17581 aacaattgat cctataaatc caaatgcctt cccttgtttt gctttagtta tattacgtga
    17641 tacgacaacc ataacaagag aaggaaacgc agcagaacct attccttgta ttaacctacc
    17701 taaaattaaa attaaaaaat gtttatgacc aaaaaatcca attaatgagc ctaagcaact
    17761 taaaataatc cctaaaataa gtagtttttt aatgcttact tgatcagata atttgccgta
    17821 tactgctgta ccaattgaaa aagttagcat gtaggcagta ttaacccaat tagtaatagc
    17881 aggtgaagta ttaaaagaaa tagctatatc aggaagtgaa acgtttaaaa ccatttcatt
    17941 taatacgcta aaaaatgaaa gaatacagag ccaaaataaa atattataac ttaagctttt
    18001 aattttattg tttatatagt tcaactttta cctcttttgc tcgaggtgat tgaagtttaa
    18061 ggggttagtt attctttcac ctcaaataaa ttccccaatt tttatataag cacttcatat
    18121 gaatcctcct ctattattat gactctaata tatcattttt ttatcgtaac aacaacaatg
    18181 tccaccaccg gcttatataa gacaagttaa atagttagtt aacataatag gtcgttatca
    18241 gaactacaca aacatcttct gtaaaaaacc ttttttgcgt tgttttaata caccaatttt
    18301 actcgattgt ttttctatta attcatctag ttcattgaaa aaatctccta ttttttcttg
    18361 ttcagaattt tttggcacca tcactttgag cttatcaaaa cctgacattc gaagagattt
    18421 aactgttgat ccaacagcat attttaagaa atgattattt tgtaatgaca gataatagta
    18481 aagataatta ttattaatat taatatcgta aatactataa gctctttgat gtaaggagta
    18541 tttcccacta aagtatcttg gtaaaaattt acttccttca cctggatata taatcgctgt
    18601 ttcatcaaaa tcaaaagtat ttaaatattt aacttctaca gagcggtcaa aaaatttaaa
    18661 ttttccatct tgtatattat cttgaacatt tttacttcca gtcttaactt tagctatttg
    18721 cataagtttt tttatttccc attctggata atcattccca ttctcatctt taaatcttaa
    18781 ttcctgtgaa aaaatctttt gcatatatcc ctttttctgt tcttctaatt tcgctaactt
    18841 ttgttcctct aattcaattt gtcggtcaag tttgctgaaa aattcaccga ttttttgttg
    18901 ttcctgttgt tcaggataat taatttctac tttagctatt tcattcttgt taattttttt
    18961 gggaaatgct atatgcaatg tctttctcca taattcattt tgaactgatt gagaacgaat
    19021 taatgattct agaaaataag aatttaattt ctttggtttt aataatgcta aacttacata
    19081 gtaggctaaa tattcgtttg tttctacaac atttggtgtc ccaacatctc ctatacgagt
    19141 cattaaaaca tcaccgaatt ccggacgaat tttaaattcc ttttcaaatg cttctttaga
    19201 aataaattta ttagaattta aggtttttat attttcaaca gatagaaatt taataccttc
    19261 acttgtatat ttcggtgttt gatgagttcc atcataaaca ttcgcaacag ttcctaattt
    19321 actattttcc cactcccctt caaactctgg gaatcttaat tctggtacat tcttcagttc
    19381 attagtcatg tgtcaccact cctaattctt ttaagaagcc ttctatttct tgctcaactg
    19441 ctttaatttc atcatcgata ctatttaagt ctttttgaac ttgttctaaa tcaataggtt
    19501 cttcttcttc aaatgtatcg acatatcttg gaatattaag gttatagtca ttttctgcga
    19561 tttcttctaa acttgccgca taactatatt tatctaatgt ttcgcggttt ttatacgttt
    19621 caacaatttt ttctacatct tcggttgtta aatggttttg attttttcct ttttcaaatg
    19681 attgcgaggc atcaataaac agtacattat catcagcttc acgacatttt ttaaatacta
    19741 atatgcttgt cggtatcgat gtcccaaaga ataagttgga tggtaaacca ataattgcgt
    19801 ctaaataatt tttttcttta attaaatact gacgaataac accttcagct gcgccacgga
    19861 ataatacacc atgtggtaaa acaacagcca ttgtgccatt atcatctaag tggtaaatca
    19921 tatgttgaat gaatgcaaaa tctgcttttg atttaggtgc taatttccca taattactaa
    19981 aacgtgggtc ttctaagaat tgtggatctg agctccattt cgcactataa ggtggatttg
    20041 caacaacagc ttcaaaacgt tcgtctgaaa tagccggatc ttctatcgta tccccatttt
    20101 caatcttaaa attcgcatag ttaacatcat gtaataacat gttcatacga gctaagttat
    20161 acgttgtact attgtactct tgaccataat attgacgtac attagcttca cgcccaacac
    20221 gaaggagtaa tgaccccgat ccacatgtag ggtcataaac gctcttaata tctttcttat
    20281 ttgcggttac aattttagct aaaattgttg aaacttgttg tggtgtatag aattcgccag
    20341 cttttttacc cgagcttgct gcgaattgac caattaagta ctcataagca tcacctaaca
    20401 tatcgatttc catatcacta tgaacaaaag gtaatgtaga tatcttcatc attacttttg
    20461 aaatcaattt tgtacgtgca gcattagagt tacccaaacg tgaagaatta aggtctaaat
    20521 catcaaataa gtgaataaag tcatcttcac tatcatgacc ccgtgtagaa ttttctatgt
    20581 ttttaatcgc attgctcagg tcttccattt caaaagcttg tttctcaatt tttttaacta
    20641 agtgaccaaa tagatattgt ggttcaatca cataaccaat acgtgaaata aattcttgtt
    20701 ctaagacggg tctataatct tcatctgcca tcgcagtttc ataatctata ttgtcttcag
    20761 ctaagagtat ttgtgcttgt tcttcaattt tttcacttaa gaaacgataa aaaatcatac
    20821 ctaagatata gtttttaaac tcgttggcat ccatattgcc acgtaagtca tcagcgatag
    20881 accatagatt tttttgtaat tcagcttgtt gttggcgttg tttttccgta atagacattt
    20941 aattgtcctc cttgaataaa gtgttagata agaattgctt ttttaatcga ctttgccttt
    21001 gttttaatac gtttaattgt ttttctttaa taccaatttg cccaatcaac cgttgtcgtt
    21061 caattgaagg taaggtaata tagagtgatt ttaactgttg atgtgttagt ttttttattg
    21121 ttgagccacc ttgcatatat tgcttatatt gtgattgtac ctctggtgct agttgaaacc
    21181 aatagactaa aaaagcaggt tccaataagt ctgaagtaac ttcaattttt gtatagttat
    21241 aaggtaaaat tgaaccatcg tgtcttgagc tcactaaggt gcactcacct gtcatcatac
    21301 ttaggacaat atcatcttta cgtacaacgg ttgctcttga tgtatctttt aatttgatga
    21361 ctctaggttg atatgtatca tctatggtta accctaaatc tatatctaac atattttgat
    21421 catataccat ataacgattc cccaggtcac tctcatcaac ttctaagcgc tgtattaatg
    21481 tgccactttg ataattaaca taatctttta acataccaga cctcctgtag ttttgttttt
    21541 ctacaaaaca aatgtagcat gatttcaaaa taaaaacaag tgtagtttta aaaaactaca
    21601 cttgttttta ttaaacacta tattttttaa ccatatcttt gataaatgat ttaacacgct
    21661 ttattttttt agtacgtatt aaaaggccgc cagaaacgcc ttcttcaatt aagttattat
    21721 ttaaatgacc actaaattca aattccttaa ctaacgattt caataattct aacggataat
    21781 ctgtttcctc agaaaattgt tccagctctc cgaccttcac tttagattca taattataat
    21841 aagcatcatc aattgaatca ccttcattta agtttggtac gactttatct aggaatgttc
    21901 gaattaaatc ggatttcaat ctcaattggt catcgtcagc tttatcaagc actttacgaa
    21961 tctctttaat gtctttttct tgttgttctg tatcacttaa atcaatttga tttaataaat
    22021 ctaaaatata ctgaacatta atcaaatcat ttcgtaaaat ctcaatatta aaatcaatat
    22081 tgtctaatat agattctccc tctagagttt ctttatcagg tcgcatcact ttatcataga
    22141 tatctaaata tttaccttta taatcttcat atgtttgttc atcaatacct aacatttcct
    22201 tatcaaatgc aaattcatca aacgttttta acttttgcat atgcttggct aactcacgat
    22261 atgcgattac aaaatcacgc tgatcttctt ctctttctaa ttggtctacg gcttgaggtg
    22321 tttcagctaa ttcaaatagt tcgatcagag cctgtttaaa tttcgttaag tacgcttgga
    22381 acgataagct caataccgta tcggtattgt ctgttttaga gaaaagctca atagcctcat
    22441 ccgttttttc ttttaagttt ctataagcaa caatatttcc atagggtttc gttggctctt
    22501 ccacacgatt ggtacgtgag taagcttgaa taagcgtatg atgttgtaaa ttacgatcaa
    22561 catataacgt attcaatttt ttactatcaa agcctgttaa gaacatatcg acaacaataa
    22621 gaatatctaa tttttgattg ggtaatcctt ttttgacacg gtttgataca tcattgaagt
    22681 aaccatcaaa cgtatccgtt gagaaatttt tatcaaaggt ctcattatac gtttgaatga
    22741 taccttctaa tatatctctt cttgtttgtt catccatcgt atcatctatg gcttcgttat
    22801 cttgataact gaatattgtc gtgacattaa ggttatgtac accttgtttc ttcaattttt
    22861 ggaaaacacg ataatattga atcgccattg gaatactttg aacggtcaac atacctgtgt
    22921 acatttgatc acgtgttttt ttattatgat tcgcaataat atgttctgct actttttgaa
    22981 cacgttcgtc tgccatccat atttcagctt cattaatttt attaacataa ccatcttcga
    23041 taattttttc actacggtca aacgtattca tatattcaac agaaaaacct agcacgttac
    23101 catctctaat cgcatctttg attagataat ggtgtagaca ttctccaaaa atatccgcag
    23161 tcgcgcgtcc atcttgactc gcattctctt caaatctagg tgttcccgta aaaccaaagt
    23221 attgggcgtt tccgaaatgt tgtctgatga tacggtgcat tgaaccaaat tgtgttcgat
    23281 ggcattcgtc aataataaaa acgactttat cttctttata acgttccatt gctggatgtc
    23341 ctgatttaat cgcattatcc attttttgaa tcgtcgtaac aattagtttc cgtgtaggat
    23401 catccatttg tttgagtaac tttttagtat tgaacgtcct atcaacagaa tctgactcaa
    23461 acttattaaa ttcccctaaa gtttgaccat ctaggtcttt gcgatcgact aagaatataa
    23521 ctttcttaat atctggttct tgcgctaata tttgactggc tttaaacgat gtgagggttt
    23581 taccactccc tgttgtatgc caaatataac cattgttatt tgtttctata gctcgattta
    23641 acaaagcctc tacagcataa acttgatacg gtctcaaggc cattaatatt ttatctgttt
    23701 cattaataat catataacgg ctaatcattt tagcaatatg gcacggttct aagaaagatt
    23761 caataaaatc tttaagcaca ttaatacgct catttttttc atcgctccag tagaacatat
    23821 gacttttcat gattttttga tcgctattcg cgtagtagcg tgtttccatt ttattactca
    23881 caacaaacat ttgtatgaat ctgaatagcc ctgtatagtt ttgacggcga taacgttcaa
    23941 tctgattaaa agcttctgta atcgcaacgc cactacgttt aagttcaatt tgaaccaaag
    24001 gtaatccatt aattaaaaca gttacatcat aacgactttt gtgtgtatca tttacactca
    24061 cttgatttgt gacttgaaat gtattttgac accacttttt tatattcatt aagctaagat
    24121 aaacttttgt ttcatcgtca cgttctagta cgtatttatc ccttaatatt tgagcgcttt
    24181 caaatacgct tttatcactt atatcaatca tgatacgttt aaactcacta tctgatatag
    24241 gcgtaccctc taacttatct gcatttcgtt catttaaaat acgtctaaaa ttctctttta
    24301 attgtgtttc gttgcgcaat aatacacgct cataccccaa atcttgtagc tgtttaatca
    24361 cattttcttc taaaccatat tcactttggt atcccaaatt aatcgctcca ccctattaaa
    24421 tttaagtata attaaatatt aacatatcaa aaattaaata tatgatataa aaaacgctgc
    24481 aagttcttta acttgtagcg tttttttaat aaatatagat tttaaaacaa taattagcta
    24541 ccaaataaac ggttccagaa tccttttttt tgttgcgttt cttcactttt ttcttcaata
    24601 tcactatcat tgtcatttga attagataga tcatcttgtg tactttcatg actttgtctc
    24661 tcagatatat cctcatattg catctctgat tcttggtctt gattaatgtt tacagaatta
    24721 gtagtatctg tagtttcttg tacatcaacg ttttttctat cgttattaga tgtatcaagg
    24781 ggataattaa ggtgtctctc ttcctctaat tggttttcta gtttttgaat ttttttattg
    24841 ctttctaaag ctaatatttg ttgattttca agcaactttg atctttcctg taactctttt
    24901 ctatagaatt ctaatgttgt ttcatgacga ctttcttgtt tttcaatttg cctatttaag
    24961 gtgtcaattt gatgtttaag tatttctatt atctgagcat cattttcaga ctcaacatta
    25021 tccgattcat tattttttat atccgctgta ttactttcga aaccatattt ttttttattt
    25081 tcatttaccc tttgaatgat tctttctata tcagtatcgt ctttaataaa tgaagtattt
    25141 tcctgtttta ttgtctctat atttagtcgt ttaatattat taaaaattgt ttgcttacta
    25201 acctttaatt cctcactcaa cattttcaca cttttcatac aatcaaacct ttataaatag
    25261 tttgtcaaac ctttataccc tattatataa ctgtaaccac tgaaatacaa atatacatta
    25321 aggaaaacaa aaaatagctt atcaatgttt tatctagggt taataagatt tatcaatact
    25381 ttgtcaaacc tttatcaacc tttgacaatc gtctatcttc tccttttaca accctattta
    25441 aagtgctata atataattaa catatcaaaa acccccaact actggtaata gtcgggggtt
    25501 ggtaataaaa cgttatagca cgtttgttta atatcaaatt tatacttgta ttatataatg
    25561 aataacatct tagtgcaagc gcctaaatct ttaaataaat gtaaagctat ataaagcgtt
    25621 ttattacctc ttaccaaact aaatttcgga aagaggtttt tatt
//
