LOCUS       NZ_CP050378            18651 bp    DNA     linear   CON 15-MAY-2024
DEFINITION  Klebsiella pneumoniae strain 51015 plasmid p51015_COL_RNAI, complete
            sequence.
ACCESSION   NZ_CP050378
VERSION     NZ_CP050378.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14421541
            Assembly: GCF_011769825.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 18651)
  AUTHORS   Chudejova,K., Kraftova,L., Mattioni Marchetti,V., Hrabak,J.,
            Papagiannitsis,C.C. and Bitar,I.
  TITLE     Genetic Plurality of OXA/NDM-Encoding Features Characterized From
            Enterobacterales Recovered From Czech Hospitals
  JOURNAL   Front Microbiol 12, 641415 (2021)
   PUBMED   33633720
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18651)
  AUTHORS   Bitar,i.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2020) Microbiology, Charles University in Prague,
            Alej Svobody 1655/76, Plzen 1 32300, Czech Republic
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Microbial Assembly v. SMRT Link v.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 473.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011769825.1-RS_2024_05_15
            Annotation Date                   :: 05/15/2024 02:59:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,873
            CDSs (total)                      :: 5,749
            Genes (coding)                    :: 5,553
            CDSs (with protein)               :: 5,553
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 196
            CDSs (without protein)            :: 196
            Pseudo Genes (ambiguous residues) :: 0 of 196
            Pseudo Genes (frameshifted)       :: 82 of 196
            Pseudo Genes (incomplete)         :: 125 of 196
            Pseudo Genes (internal stop)      :: 32 of 196
            Pseudo Genes (multiple problems)  :: 37 of 196
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050378.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..18651
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="51015"
                     /isolation_source="Rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p51015_COL_RNAI"
                     /geo_loc_name="Czech Republic: Prague"
                     /lat_lon="50.07 N 14.43 E"
                     /collection_date="2019-06"
                     /collected_by="Charles University in Prague"
     gene            374..523
                     /locus_tag="HB813_RS29995"
     CDS             374..523
                     /locus_tag="HB813_RS29995"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228284903.1"
                     /translation="MHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFFGLAELGPDGC
                     VLWG"
                     /name="hypothetical protein"
     gene            711..1061
                     /locus_tag="HB813_RS30000"
     CDS             711..1061
                     /locus_tag="HB813_RS30000"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228284904.1"
                     /translation="MFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLAVGIVL
                     ARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNALADFS
                     SEQARQEQRCFW"
                     /name="hypothetical protein"
     gene            1206..1370
                     /locus_tag="HB813_RS30005"
     CDS             1206..1370
                     /locus_tag="HB813_RS30005"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228284905.1"
                     /translation="MYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYA
                     LKKPADCRA"
                     /name="hypothetical protein"
     gene            1744..>2052
                     /locus_tag="HB813_RS30010"
                     /pseudo=""
     CDS             1744..>2052
                     /locus_tag="HB813_RS30010"
                     /inference="COORDINATES: protein motif:HMM:NF024108.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mobilization protein A"
                     /name="Mobilization protein A"
     gene            2303..3034
                     /locus_tag="HB813_RS26035"
                     /old_locus_tag="HB813_26040"
     CDS             2303..3034
                     /locus_tag="HB813_RS26035"
                     /old_locus_tag="HB813_26040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            3041..3571
                     /locus_tag="HB813_RS26040"
                     /old_locus_tag="HB813_26045"
     CDS             3041..3571
                     /locus_tag="HB813_RS26040"
                     /old_locus_tag="HB813_26045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(3599..3778)
                     /locus_tag="HB813_RS26045"
                     /old_locus_tag="HB813_26050"
     CDS             complement(3599..3778)
                     /locus_tag="HB813_RS26045"
                     /old_locus_tag="HB813_26050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            3847..4224
                     /locus_tag="HB813_RS26050"
                     /old_locus_tag="HB813_26055"
     CDS             3847..4224
                     /locus_tag="HB813_RS26050"
                     /old_locus_tag="HB813_26055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(4286..4585)
                     /locus_tag="HB813_RS26055"
                     /old_locus_tag="HB813_26060"
     CDS             complement(4286..4585)
                     /locus_tag="HB813_RS26055"
                     /old_locus_tag="HB813_26060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(4575..4838)
                     /locus_tag="HB813_RS26060"
                     /old_locus_tag="HB813_26065"
     CDS             complement(4575..4838)
                     /locus_tag="HB813_RS26060"
                     /old_locus_tag="HB813_26065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(5144..5562)
                     /locus_tag="HB813_RS26065"
                     /old_locus_tag="HB813_26070"
                     /pseudo=""
     CDS             complement(5144..5562)
                     /locus_tag="HB813_RS26065"
                     /old_locus_tag="HB813_26070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            5964..7646
                     /locus_tag="HB813_RS30355"
                     /old_locus_tag="HB813_26075"
                     /pseudo=""
     CDS             5964..7646
                     /locus_tag="HB813_RS30355"
                     /old_locus_tag="HB813_26075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            7637..7912
                     /locus_tag="HB813_RS26075"
                     /old_locus_tag="HB813_26080"
     CDS             7637..7912
                     /locus_tag="HB813_RS26075"
                     /old_locus_tag="HB813_26080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_071788963.1"
                     /translation="MSLRGKYGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMP
                     LKDNINNGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            7997..8146
                     /locus_tag="HB813_RS26080"
                     /old_locus_tag="HB813_26085"
     CDS             7997..8146
                     /locus_tag="HB813_RS26080"
                     /old_locus_tag="HB813_26085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            10136..10284
                     /locus_tag="HB813_RS30360"
                     /pseudo=""
     CDS             10136..10284
                     /locus_tag="HB813_RS30360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001318239.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            complement(10502..10651)
                     /locus_tag="HB813_RS26085"
                     /old_locus_tag="HB813_26090"
     CDS             complement(10502..10651)
                     /locus_tag="HB813_RS26085"
                     /old_locus_tag="HB813_26090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(10736..10993)
                     /locus_tag="HB813_RS26090"
                     /old_locus_tag="HB813_26095"
     CDS             complement(10736..10993)
                     /locus_tag="HB813_RS26090"
                     /old_locus_tag="HB813_26095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(10983..11417)
                     /locus_tag="HB813_RS30030"
     CDS             complement(10983..11417)
                     /locus_tag="HB813_RS30030"
                     /inference="COORDINATES: protein motif:HMM:NF020569.4"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /protein_id="WP_228284907.1"
                     /translation="MNPYPGIRLRFPGRWRAGNKRRKKAKDAENKLNEEKKKPRKGTKD
                     YGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIYEWDSQHGELEG
                     YRASDGEHLGAFDPKTGKQVKGPDPKRNIKKISLRGKYGA"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            complement(11326..12210)
                     /locus_tag="HB813_RS30270"
     CDS             complement(11326..12210)
                     /locus_tag="HB813_RS30270"
                     /inference="COORDINATES: protein motif:HMM:NF015479.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_266096966.1"
                     /translation="MSKIVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHI
                     AVVTGRPMSVPVVDAKPTKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDS
                     RPAGFTAGGNSREAVIRFPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHP
                     EEGLKREYDKAKAELDAEDKNIATLNSRIASTEKAIPGARAAVQRADKKVKEAEANKDD
                     FVTYNPPHEYGSGWQDQVRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMES
                     RKQKEKKSEGCRK"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            complement(12195..12689)
                     /locus_tag="HB813_RS30275"
     CDS             complement(12195..12689)
                     /locus_tag="HB813_RS30275"
                     /inference="COORDINATES: protein motif:HMM:NF015479.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_266096967.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMCQK
                     S"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            13091..13509
                     /locus_tag="HB813_RS26100"
                     /old_locus_tag="HB813_26105"
                     /pseudo=""
     CDS             13091..13509
                     /locus_tag="HB813_RS26100"
                     /old_locus_tag="HB813_26105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            13815..14078
                     /locus_tag="HB813_RS26105"
                     /old_locus_tag="HB813_26110"
     CDS             13815..14078
                     /locus_tag="HB813_RS26105"
                     /old_locus_tag="HB813_26110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            14068..14367
                     /locus_tag="HB813_RS26110"
                     /old_locus_tag="HB813_26115"
     CDS             14068..14367
                     /locus_tag="HB813_RS26110"
                     /old_locus_tag="HB813_26115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(14429..14806)
                     /locus_tag="HB813_RS26115"
                     /old_locus_tag="HB813_26120"
     CDS             complement(14429..14806)
                     /locus_tag="HB813_RS26115"
                     /old_locus_tag="HB813_26120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            14875..15054
                     /locus_tag="HB813_RS26120"
                     /old_locus_tag="HB813_26125"
     CDS             14875..15054
                     /locus_tag="HB813_RS26120"
                     /old_locus_tag="HB813_26125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(15082..15456)
                     /locus_tag="HB813_RS26125"
                     /old_locus_tag="HB813_26130"
     CDS             complement(15082..15456)
                     /locus_tag="HB813_RS26125"
                     /old_locus_tag="HB813_26130"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223175405.1"
                     /translation="MMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYR
                     KVERFAIENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNV
                     PVPELPEDKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(15453..15611)
                     /locus_tag="HB813_RS30045"
     CDS             complement(15453..15611)
                     /locus_tag="HB813_RS30045"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228284908.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGRMFSVLS
                     TGPSIWR"
                     /name="hypothetical protein"
     gene            complement(15618..16349)
                     /locus_tag="HB813_RS26130"
                     /old_locus_tag="HB813_26135"
     CDS             complement(15618..16349)
                     /locus_tag="HB813_RS26130"
                     /old_locus_tag="HB813_26135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(<16600..17013)
                     /locus_tag="HB813_RS30050"
                     /pseudo=""
     CDS             complement(<16600..17013)
                     /locus_tag="HB813_RS30050"
                     /inference="COORDINATES: protein motif:HMM:NF024108.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /name="TraM recognition domain-containing protein"
     gene            complement(17282..17446)
                     /locus_tag="HB813_RS30055"
     CDS             complement(17282..17446)
                     /locus_tag="HB813_RS30055"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228284905.1"
                     /translation="MYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYA
                     LKKPADCRA"
                     /name="hypothetical protein"
     gene            complement(17591..17941)
                     /locus_tag="HB813_RS30060"
     CDS             complement(17591..17941)
                     /locus_tag="HB813_RS30060"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228284904.1"
                     /translation="MFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLAVGIVL
                     ARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNALADFS
                     SEQARQEQRCFW"
                     /name="hypothetical protein"
     gene            complement(18129..18278)
                     /locus_tag="HB813_RS30065"
     CDS             complement(18129..18278)
                     /locus_tag="HB813_RS30065"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228284903.1"
                     /translation="MHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFFGLAELGPDGC
                     VLWG"
                     /name="hypothetical protein"
     BGC             964..17689
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(8250..8829)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.197"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9816..10397
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.872"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          2304..3031
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.35e-150"
     Typing          complement(15622..16349)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.35e-150"
ORIGIN
        1 cccacaaaaa tccacggtgc tggacgcacc tggcgaagca gcaaagctgc tcctgatttt
       61 gcgggtggtc agccgctcgc tatggcgaac tctgacgggg gccggaacac cggaaaagac
      121 cgcactgggg tgccgccttt tcctctcaca cgctggggcg tgctcgttgt tcctccgggc
      181 tgcgcctttt ccgcatgggg cggaaagagg ctggcctccg tggtgaaagc tgaacgcaat
      241 caccacggac gtgaccgccg ccgccatgcc ttggggcatg tccgcggctt gtgcagcggg
      301 gctgcacatc acgccggcaa accatcgtct gaaggagaga gaacatgttt aatacggatt
      361 cgcttgcctg gaagtgcaca ttccggagct ggcccggcag atttatccgt gggtcagctg
      421 gctgtaccag gagtattacg gtctggccgg ggctttccta gttatcggcc tgtttttcgg
      481 tctggctgaa cttgggccgg acggatgcgt tttgtggggc tgagtcataa ggagcgacgg
      541 gagtatgccg atcgctataa gcgcgataat aaacggccag cgccattttc ggtgctggcc
      601 tcgctggatt cgcccgggcg gatggtcagg gcacgtcgac atgtctggaa ctacgcgtac
      661 tggctgaccg gcgcggccgg tctggccctt ctggggggct ggttgtcgcc gtgtttatcg
      721 agagctgggg agaaaccgtc ctgcgtccgg acctctacgc aaacgcagat tattacctgc
      781 tgcagccggc taacctgttc gggattgcct ggtgcgcggg cgggctggct gtcgggattg
      841 tgttggcgcg gctgctggcg ttcctgctgc ttgacggtca ttttgcggct gctgacgagg
      901 cggtgaacgc gaaactgaat caggagagcc ggcgcagcag ccagcggaca ggagagatga
      961 ccgacgtgcg ccacctgcat ttcggggagc cggtaccggt taatgcgctg gccgattttt
     1021 cctcggagca ggcccggcag gagcagcggt gtttctggta aggatgagca gggcaagccg
     1081 gtgctggttc cgcgtgatac ctggcgcaag accaacattc agatcctcgg cctgcccggg
     1141 agcggcaaga gcgtgatggc caccaacgcg ctcattcgct gcgtacgcga tttcgggacg
     1201 cggtggtgta cttcgacccc aaaggggacg catgggcgcc gcacgtcttc cgggcgcact
     1261 gtccggactt caccctgctg gatctgcggc cggggaaacc ggcgcagctg aatctgttcc
     1321 gcgatctcga ccagtacgcg ctgaaaaaac ctgctgattg ccgggcttaa cctgggcgag
     1381 accggcgacg tggcggacca ctaccgcatc agcgagcaga aagcggcgaa gctgattgcg
     1441 gagcagtttc cgcagggggc aaacattcag caggtgctgg cggcggcgta cgcgctgccg
     1501 gaggccctga aaaaggacgt gaaggggttg atcactaggc tggaaaacgt cgctgacctg
     1561 agcgtcctgc agacggacag tggcatcgat gtggcgggga ttatcaacgg cggcggctgc
     1621 ctgtacgtta tcggctcgat ggacgacgag gcggtgatcc gtgtgcaaaa aatgctgttt
     1681 gcccgctgcg cgcaaatcat cattgcgcgg gacgagttcc gggagtggcc acacgtcagc
     1741 gtgatgctcg atgaaattaa atatctgctg tcgaagtatg tactgaacgc actggggacg
     1801 ctgcgcagcc gggactgcaa tctgttgctc gcgcaccagt cgctgggcga tttcgggcag
     1861 tgcgggcagg atctgcccgc tgaatttgtg aaaaccacgg tactggataa cacgccgatc
     1921 cgctggtttt accgggcggc cagcctggag tccgcgcagt gggcggcggg gcagaccggg
     1981 gaaatcaggg tggacgtgga gcgccgccgt gccagccggg aggcggggaa cgtggagcat
     2041 atcagcgggg acagcttcat ccagaaggag gcgcggccgc tgtttgacgt gaacaccctg
     2101 caacacctgc cggacgggtt cgcggtcatg accgggctgg gtgtggcccg gatggcgttc
     2161 agcagtccgc tgcgggttga gcgccgggaa atcccgttgc agcgtttccc ggtgctggcg
     2221 aaaaccgatc ccctggcgga gttccggccc cggccgacgg cggcgggccg aaagcggatg
     2281 atgattttgc ggggatttac tgatggcgct ggagctgtac aacgtcagcc acgcgaaacg
     2341 acaggcgcgg aacgcggaga aaacccggct gaccctgcgc tggttgcggg aagagctgtg
     2401 ttccacggcg gagctggttg cgcggcggct ggggattgcg gcggtgcagc cggtctaccg
     2461 cttcctcgac agcctggtgg cgaaagggct gctggtccgg accaaatatc cggtggacgg
     2521 ccgtcaggtc agcgtgtggg ggctgacgcc gcatggcgtg gcgttctcgt tcgacgagga
     2581 cgaaccgctg gcggatgtta ttccgtttca gccgtcaagg gtgtcggcag cacatctgcc
     2641 gcaccggctg gccgtgcaat ccctgcgcct tgatatggaa gccagagggg ccaccggctg
     2701 gcgcattctg caccgtctga gtcttaaagg catgaaagtg ccggacgccc tggcggagct
     2761 ggacggtaaa acggtggcgt ttgaggtgga gcgcaccgtc aagagccgtc gccggtatca
     2821 ggaagtggtg tccgggtatc tgttcaaccg caaagctaac ggcatcgatg aaatctggta
     2881 catctgcccg gaccgggcga cgcaggtcag ggtgcagcgg gcaatcctgt cggtggatga
     2941 aatcgtgaac ccacagaccg gcgaggcccg caaaacggca gagctggatc gtgaacggtt
     3001 gtttgcgtgc tttaaattta tgacaacgga gtgagggatt atggcgctgt acatggtatt
     3061 tattgaagac gcggaggacc ggaacggcga gcgctgcatc atgccgacca gcgagcatct
     3121 ggaagatatg gtggtgctcg cctggcagac cggggcgtat gttttctgtt ttgtcgaccg
     3181 ggcccagcat ctggcgatga tgaaatccat cgggatgtat gacgagcggc tcaacagcga
     3241 cgaaaaagcc acgtactttt tcactggtaa aaatccgcaa tgggaacgga acaaacccac
     3301 aggaatgaag ctgtgtgatt acctctatcg caaggtggag cggttcgcca tcgagaacgg
     3361 tgtgcaggtg gttgatgccg ggaagtgctc accggagcag attaacgcga tgattgacgt
     3421 ggtgagtgag cggcacgggg aaagcgcggt gaacgagaag ctgaaagcgg agctgatgcg
     3481 ggaatataac agccgctatt ttaacgtgcc ggtacctgaa ctgccggagg acaaacctgc
     3541 ccgccggtgg tggccgttcg gcaaaaaata aatgccagca ccggccatgc cggtgctgtt
     3601 attcctcccc gagcttatcc cgcatcacct gccagagtgt ttccgcatcc tcgtgtagcc
     3661 gctcgcacat gtcggccggg gtatccatat ccagctcatt cagtttatcg agcaatagca
     3721 gcgactgctc cttaataaat ttagccatat tgagggctgt tttttcctgt tttgtcatga
     3781 ttctttcctt ccgggcatgg tgtgcgcctg tcaggtatac tgtctcaaaa atagcggggt
     3841 gagacaatgg cgtgggtgac ggtgagacag gcgacggaac tgacgggtaa agcccgaagt
     3901 tccctgtatc gggatatggc gaaaggccgc gtatcatacc gtacggaagc tgatggcggc
     3961 cgggtggtgg ataccagcga gcttatccgg gtgtacggtg agttaagaca ggatgagact
     4021 cacgagcggg acgagttgag actgtcgggt gagactgaaa aaatggcctc cgacgcgttg
     4081 atcgcggaga taaaagcact cagggaggag gtggccgggc tacggcagga aatgcagtcc
     4141 atgagactgc tggaacacaa accggagaca gcagagaccc cggccggaac accgcgccgg
     4201 tggtggccgt ggggaaaacg ctgacgcgct gtgcttgtcc aaccggcgac ggccacgcaa
     4261 tgaattgcgt ccccgtcacc ggttattaga gaacaatatg gggattctgg cgctggccga
     4321 ccacggccag aacccggact tttctggtct ggtcatcaac atcatagagg acatgctgtc
     4381 ccatcagact gatccggcga acgtcctcgc catagcgtga gtccacttca tagagtcgcg
     4441 ggaagtcggc cagtttgtcc gccgcagcga gaacccggtc ggtaacgttc tgcgcatccc
     4501 acagggatga attttccgcg atatagtcaa acagcgtcgt tacatcctcg atggctccct
     4561 gcttccattc cacgtcatac ggcatcgcgc agttcctgat aacggccatg caggcgctgg
     4621 cggagttgtt ccgtggtcat acccggacgc gtgtcagcac gggcggcggt cactttggcg
     4681 cgaacctgat cttcatactc tgcctgggcc agttcttcgt tagccagtcg ctgcaacagc
     4741 gcagctttgt ccgggccacc ttccggcagt atgcggggca ggctttcagc cagttcccga
     4801 agaaagttgg cgttttcgta gtgtgtagtg ttgctcattg cggagcctcc cgggttaatg
     4861 cggcaatatg aaggaagttt agcagggggc ggtctgaaag aatatggtcg tgtcagtcag
     4921 gctgatgaag cagaaagtcg gtaaaaaagg gcttacggca tccattttac gtcaaaacat
     4981 atgccatgca gttgcgtgca taggcatgca ttaggataaa atttatcggg cgcgtttccg
     5041 gcagttttcc gggggggttg ttgcctgttt tatcccgtag ccgccggaaa cgccctgagc
     5101 ccgtctgagc ggtgcgcgta atgacgcgtt atggtaaatc cacttactgt ctgccttcat
     5161 agccatcgag ataaacagct gaaatggtgt cagccagtag ccttgatttt ttcggtgtga
     5221 ggtctttgct gcggtaatcg gtacccgcaa attgtgttgt gccttggagt gagtttaaaa
     5281 attcctgact gtgaaactgc tgaatgcgtt gctgcacatc actccgtgat tttccggtcg
     5341 ctttatcctt tgcgcccata tcccagaact gccggaaaaa ggcaccatca ttcgtgttgt
     5401 gtcagctttc tgggtggaaa aattgggatc aaaaccgtca tctgaagcat atacgtaatg
     5461 ccgggtatgc tgttccacgc tgccctttgg agcacaggca gtgagagttg ctgtcgctgt
     5521 tatcatggcg ataagacaca gtttgctgcc ggaacgtctc atgagcgtct ccttaccttt
     5581 aattcttttt tctcattgag ttatatatcc gcaggctatc ttatcatcag tttctgaccg
     5641 tgttcagtga ccgaacaacc cgaaccagac cccccgtttc ttttcctgtc ccggaggggg
     5701 ctttctggta tctcatataa tgatttcagt aaaacatact gaggccggag aacggcgccg
     5761 tttgtgctgg tttttgttgc atctggaggg gattgcgcat ggtgtgagtg gctgtttttt
     5821 tgatcatttt cacaaaacgc aaatttacag acttgacatg aaaaacaagg cagcgtaatt
     5881 tttatactgt atataaaacc agtggttata tgtacagtat tttattttag tttattgttt
     5941 taaaagtcaa agaggaaaag tatatgagtg gcggagacgg acgaggtccg ggtaattcag
     6001 gtctgggaca caatggtggt caggccagtg ggaatgtgaa cggtacatca ggtaaaggtg
     6061 gcccttcatc aggtggtggt acggatccaa acagcgggcc gggctggggt acgacgcata
     6121 cacctaacgg ggatattcat aactataacc cgggggagtt tggtaacggc gggagtaaac
     6181 ccggtggtaa tggcggtaac agcggcaatc atagcgggag ctctggtggc ggacagtctt
     6241 cggccaccgc gatggccttc ggtctgcctg ccttggccac tccgggggct gaaggactgg
     6301 ctttatccgt ttccggcgat gcgttgtcgg ccgctgttgc tgatgtgctg gctgccctga
     6361 aaggtccgtt taagtttggt ctgtggggga ttgcgattta cggagtgctg ccttctgaga
     6421 tagcaaaaga tgatccgaaa atgtgtcaaa aatcgtgacg tcattgccgg cagacacggt
     6481 aacggagacg ccggtcagct ccctgccgct ggaccaggcg acggtcagcg tcactaaacg
     6541 tgtggcggat attgtgaagg acgagcggca gcatattgcg gttgtcaccg gccggccaat
     6601 gagtgttcct gtggtggatg cgaaaccgac aaaacgtccg ggggtattca gtgtgtcgat
     6661 tccgggtctc ccgtctctgc aggtgagcgt acctaaaggt gttccggccg cgaaagcccc
     6721 gccaaaaggc attattgctg aaaaaggtga ttcacgtccg gctggtttta cggccggtgg
     6781 taactcccgt gaagccgtta ttcgtttccc gaaagagagc ggacagaaac cggtctatgt
     6841 gtcggtgacg gatgttctta ctccggcaca ggtaaaacag cgtctggagg aagaaaagcg
     6901 tcgccagcag gcatgggacg ctgctcaccc ggaagagggg ctgaaaagag agtatgataa
     6961 agcgaaagct gagctggatg ctgaagataa aaatattgcg accttaaaca gtcgcattgc
     7021 atcgacagag aaggcgatcc ccggtgcaag ggctgctgtt caggaagccg ataaaaaggt
     7081 aaaagaggca gaggcaaata aagatgattt tgtgacttat aacccgcctc atgaatatgg
     7141 ctccgggtgg caggatcagg ttcgctatct tgataaggat attcagaatc agaatgagaa
     7201 attaaaagct gcccagacat ctttaaacga aatgaatgaa tccttatcca gggataaggc
     7261 tgcgctttcc gggcgatgga gagccggaaa caaaaggaga aaaagcgaag gatgcagaaa
     7321 ataaattaaa tgaggaaaag aaaaaacctc gtaagggaac taaagattac ggccatgatt
     7381 attttcctga tcccaagact gaagatatta aggggttggg agagttgaaa gagggtaaac
     7441 ctaaaacccc taaacaaggt ggtggtggta agcgggcccg atggtatggt gataaaaagc
     7501 gtaaaattta tgaatgggat tcccagcacg gtgagcttga agggtaccgc gccagtgatg
     7561 gcgaacacct cggggcattc gatccaaaaa cgggtaagca ggttaaaggg ccggatccaa
     7621 aacgaaacat taaaaaatat ctttaagagg taaatatggg cttaaattac atattcattg
     7681 gtttgataag aaaaccgaag agtttaaagg tggtgaatac tcaaaagact tcggtgatga
     7741 tggttctgtc attgaaagtc tggggatgcc tttaaaggat aatattaata atggttggtt
     7801 tgatgttgaa aaatcatggg tttcgatatt acagccacac tttaaaaatg taatcgatat
     7861 tagtaaattt gattactttg tatcctttgt ttaccgggat ggtaactggt aagcaaaagt
     7921 tatcaaggat gatttgaaat acagacttcc ggtgttcagg gatgaatacc ggggttttta
     7981 aatacaggga aggtatatga aaaaggtaaa ggttgttttt ctttttatat tgattttttc
     8041 aggctttctt ctggtcgcat gtcaggcaaa ctatatccgg gatgttcagg gtggaacggt
     8101 ggcaccatcg tcctcctctg aactgacggg gatcgcggtt cagtagaaaa gatcaaagga
     8161 tcttcttgag atcctttttt tctgcgcgta atcttttgcc ctgtaaacga aaaaaccacc
     8221 tggggaggtg gtttgatcga aggttaagtc agttggggaa ctgcttaacc gtggtaactg
     8281 gctttcgcag agcacagcaa ccaaatctgt ccttccagtg tagccggact ttggcgcaca
     8341 cttcaagagc aaccgcgtgt ttagctaaac aaatcctctg cgaactccca gttaccaatg
     8401 gctgctgcca gtggcgtttt gcgtgctttt ccgggttgga ctcaagtgaa cagttaccgg
     8461 ataaggcgca gcagtcgggc tgaacggggg gttcttgctt acagcccagc ttggagcgaa
     8521 cgacctacac cgagccgaga taccagagtg tgagctatga gaaagcgcca cacttcccgc
     8581 aagggagaaa ggcggaacag gtatccggga aacggcaggg ttggaacagg agagcgcaag
     8641 agggagcgat tcatcggaaa cggtgatgat ctttaagtcc tgtcgggttt cgccactcct
     8701 gactgattca tggttgagcc accggctccc acagatgcac cgaaaaagcg tctgtttatg
     8761 tgaactcagt caggagggcg gagcctatgg aaaaacgcca cctgcgtggc cttgccgttt
     8821 ttgcctcaca tgttagtccc ctgcttattc acggaatctg tgggtaactt tgcatgtgtc
     8881 cgcagcgccc gccgcagtct cacggccgga gcgtagcgac cgagtgagcg aggaggcgcc
     8941 aatttccccg gcacctacaa gacggacacc ggacgcgctg atgtggcata ttgtcccctg
     9001 attaagtctt tatattccct gataataaat taccaggata ggtgaatcat atcggttttt
     9061 tcgctgaaca ttttacgtta acctatctct gttgcttttt ttctccttac ggagaaatac
     9121 aggtcatccc cgcgagggcg tggctgacct cagggggata tcccctgctt acgctggctg
     9181 gacgccaccg acgcacggtc tctccccctc tttctggctc cgtccggctg gacgccggcc
     9241 acgccagaaa ttcacccggc ccccgtcagg ctcacgcctg accacccaca aaaaatccac
     9301 ggtgctggac gcacctggcg aagcagcaaa gctgctcctg attttgcggg tggtcagccg
     9361 ctcgctatgg cgaactctga cgggggccgg gtgaatttct ggcgtggccg gcgtccagcc
     9421 ggacggagcc agaaagaggg ggagagaccg tgcgtcggtg gcgtccagcc agcgtaagca
     9481 ggggatatcc ccctgaggtc agccacgccc tcgcggggat gacctgtatt tctccgtaag
     9541 gagaaaaaag caacagagat aggttaacgt aaaatgttca gcgaaaaaac cgatatgatt
     9601 cacctatcct ggtaatttat tatcagggaa tataaagact taatcagggg acaatatgcc
     9661 acatcagcgc gtccggtgtc cgtcttgtag gtgccgggga aattgcgcct cctcgctcac
     9721 tcggtcgcta cgctccggcc gtgagactgc ggcgggcgct gcggacacat gcaaagttac
     9781 ccacagattc cgtgaataag caggggacta acatgtgagg caaaacggca aggccacgca
     9841 ggtggcgttt tttccatagg ctccgccctc ctgactgagt tcacataaac agacgctttt
     9901 tcggtgcatc tgtgggagcc ggtggctcaa ccatgaatca gtcaggagtg gcgaaacccg
     9961 acaggactta aagatcatca ccgtttccga tgaatcgctc cctcttgcgc tctcctgttc
    10021 caaccctgcc gttttcccgg atacctgttc cgcctttctc ccttgcggga agtgtggcgc
    10081 tttctcatag ctcacactct ggtatctcgg ctcggtgtag gtcgttcgct ccaagctggg
    10141 ctgtaagcaa gaaccccccg ttcagcccga ctgctgcgcc ttatccggta actgttcact
    10201 tgagtccaac ccggaaaagc acgcaaaacg ccactggcag cagccattgg taactgggag
    10261 ttcgcagagg atttgtttag ctaaacacgc ggtttgctct tgaagtgtgc gccaaagtcc
    10321 ggctacactg gaaggacaga tttggttgct gtgctctgcg aaagccagtt accacggtta
    10381 agcagttccc caactgactt aaccttcgat caaaccacct ccccaggtgg ttttttttcg
    10441 tttacagggc aaaagattac gcgcagaaaa aaaggatctc aagaagatcc tttgatcttt
    10501 tctactgaac cgcgatcccc gtcagttcag aggaggacga tggtgccacc gttccaccct
    10561 gaacatcccg gatatagttt gcctgacatg cgaccagaag aaagcctgaa aaaatcaata
    10621 taaaaagaaa aacaaccttt acctttttca tataccttcc ctgtatttaa aaaccccggt
    10681 attcatccct gaacaccgga agtctgtatt tcaaatcatc cttgataact tttgcttacc
    10741 agttaccatc ccggtaaaca aaggatacaa agtaatcaaa tttactaata tcgattacat
    10801 ttttaaagtg tggctgtaat atcgaaaccc atgatttttc aacatcaaac caaccattat
    10861 taatattatc ctttaaaggc atccccagac tttcaatgac agaaccatca tcaccgaagt
    10921 cttttgagta ttcaccacct ttaaactctt cggttttctt atcaaaccaa tgaatatgta
    10981 atttaagccc catatttacc tcttaaagat atttttttaa tgtttcgttt tggatccggc
    11041 cctttaacct gcttacccgt ttttggatcg aatgccccga ggtgttcgcc atcactggcg
    11101 cggtaccctt caagctcacc gtgctgggaa tcccattcat aaattttacg ctttttatca
    11161 ccataccatc gggcccgctt accaccacca ccttgtttag gggttttagg tttaccctct
    11221 ttcaactctc ccaacccctt aatatcttca gtcttgggat caggaaaata atcatggccg
    11281 taatctttag ttcccttacg aggttttttc ttttcctcat ttaatttatt ttctgcatcc
    11341 ttcgcttttt ttctcctttt gtttccggct ctccatcgcc ccggaaagcg cagccttatc
    11401 cctggataag gattcattca tttcgtttaa agatgtctgg gcagctttta atttctcatt
    11461 ctgattctga atatccttat caagatagcg aacctgatcc tgccacccgg agccatattc
    11521 atgaggcggg ttataagtca caaaatcatc tttatttgcc tctgcctctt ttaccttttt
    11581 atcggctctc tgaacagcag cccttgcacc ggggatcgcc ttctctgtcg atgcaatgcg
    11641 actgtttaag gtcgcaatat ttttatcttc agcatccagc tcagctttcg ctttatcata
    11701 ctctcttttc agcccctctt ccgggtgagc agcgtcccat gcctgctggc gacgcttttc
    11761 ttcctccaga cgctgtttta cctgtgccgg agtaagaaca tccgtcaccg acacatagac
    11821 cggtttctgt ccgctctctt tcgggaaacg aataacggct tcacgggagt taccaccggc
    11881 cgtaaaacca gccggacgtg aatcaccttt ttcagcaata atgccttttg gcggggcttt
    11941 cgcggccgga acacctttag gtacgctcac ctgcagagac gggagacccg gaatcgacac
    12001 actgaatacc cccggacgtt ttgtcggttt cgcatccacc acaggaacac tcattggccg
    12061 gccggtgaca accgcaatat gctgccgctc gtccttcaca atatccgcca cacgtttagt
    12121 gacgctgacc gtcgcctggt ccagcggcag ggagctgacc ggcgtctccg ttaccgtgtc
    12181 tgccggcaat gacgtcacga tttttgacac attttcggat catcttttgc tatctcagaa
    12241 ggcagcactc cgtaaatcgc aatcccccac agaccaaact taaacggacc tttcagggca
    12301 gccagcacat cagcaacagc ggccgacaac gcatcgccgg aaacggataa agccagtcct
    12361 tcagcccccg gagtggccaa ggcaggcaga ccgaaggcca tcgcggtggc cgaagactgt
    12421 ccgccaccag agctcccgct atgattgccg ctgttaccgc cattaccacc gggtttactc
    12481 ccgccgttac caaactcccc cgggttatag ttatgaatat ccccgttagg tgtatgcgtc
    12541 gtaccccagc ccggcccgct gtttggatcc gtaccaccac ctgatgaagg gccaccttta
    12601 cctgatgtac cgttcacatt cccactggcc tgaccaccat tgtgtcccag acctgaatta
    12661 cccggacctc gtccgtctcc gccactcata tacttttcct ctttgacttt taaaacaata
    12721 aactaaaata aaatactgta catataacca ctggttttat atacagtata aaaattacgc
    12781 tgccttgttt ttcatgtcaa gtctgtaaat ttgcgttttg tgaaaatgat caaaaaaaca
    12841 gccactcaca ccatgcgcaa tcccctccag atgcaacaaa aaccagcaca aacggcgccg
    12901 ttctccggcc tcagtatgtt ttactgaaat cattatatga gataccagaa agccccctcc
    12961 gggacaggaa aagaaacggg gggtctggtt cgggttgttc ggtcactgaa cacggtcaga
    13021 aactgatgat aagatagcct gcggatatat aactcaatga gaaaaaagaa ttaaaggtaa
    13081 ggagacgctc atgagacgtt ccggcagcaa actgtgtctt atcgccatga taacagcgac
    13141 agcaactctc actgcctgtg ctccaaaggg cagcgtggaa cagcataccc ggcattacgt
    13201 atatgcttca gatgacggtt ttgatcccaa tttttccacc cagaaagctg acacaacacg
    13261 aatgatggtg cctttttccg gcagttctgg gatatgggcg caaaggataa agcgaccgga
    13321 aaatcacgga gtgatgtgca gcaacgcatt cagcagtttc acagtcagga atttttaaac
    13381 tcactccaag gcacaacaca atttgcgggt accgattacc gcagcaaaga cctcacaccg
    13441 aaaaaatcaa ggctactggc tgacaccatt tcagctgttt atctcgatgg ctatgaaggc
    13501 agacagtaag tggatttacc ataacgcgtc attacgcgca ccgctcagac gggctcaggg
    13561 cgtttccggc ggctacggga taaaacaggc aacaaccccc ccggaaaact gccggaaacg
    13621 cgcccgataa attttatcct aatgcatgcc tatgcacgca actgcatggc atatgttttg
    13681 acgtaaaatg gatgccgtaa gccctttttt accgactttc tgcttcatca gcctgactga
    13741 cacgaccata ttctttcaga ccgccccctg ctaaacttcc ttcatattgc cgcattaacc
    13801 cgggaggctc cgcaatgagc aacactacac actacgaaaa cgccaacttt cttcgggaac
    13861 tggctgaaag cctgccccgc atactgccgg aaggtggccc ggacaaagct gcgctgttgc
    13921 agcgactggc taacgaagaa ctggcccagg cagagtatga agatcaggtt cgcgccaaag
    13981 tgaccgccgc ccgtgctgac acgcgtccgg gtatgaccac ggaacaactc cgccagcgcc
    14041 tgcatggccg ttatcaggaa ctgcgcgatg ccgtatgacg tggaatggaa gcagggagcc
    14101 atcgaggatg taacgacgct gtttgactat atcgcggaaa attcatccct gtgggatgcg
    14161 cagaacgtta ccgaccgggt tctcgctgcg gcggacaaac tggccgactt cccgcgactc
    14221 tatgaagtgg actcacgcta tggcgaggac gttcgccgga tcagtctgat gggacagcat
    14281 gtcctctatg atgttgatga ccagaccaga aaagtccggg ttctggccgt ggtcggccag
    14341 cgccagaatc cccatattgt tctctaataa ccggtgacgg ggacgcaatt cattgcgtgg
    14401 ccgtcgccgg ttggacaagc acagcgcgtc agcgttttcc ccacggccac caccggcgcg
    14461 gtgttccggc cggggtctct gctgtctccg gtttgtgttc cagcagtctc atggactgca
    14521 tttcctgccg tagcccggcc acctcctccc tgagtgcttt tatctccgcg atcaacgcgt
    14581 cggaggccat tttttcagtc tcacccgaca gtctcaactc gtcccgctcg tgagtctcat
    14641 cctgtcttaa ctcaccgtac acccggataa gctcgctggt atccaccacc cggccgccat
    14701 cagcttccgt acggtatgat acgcggcctt tcgccatatc ccgatacagg gaacttcggg
    14761 ctttacccgt cagttccgtc gcctgtctca ccgtcaccca cgccattgtc tcaccccgct
    14821 atttttgaga cagtatacct gacaggcgca caccatgccc ggaaggaaag aatcatgaca
    14881 aaacaggaaa aaacagccct caatatggct aaatttatta aggagcagtc gctgctattg
    14941 ctcgataaac tgaatgagct ggatatggat accccggccg acatgtgcga gcggctacac
    15001 gaggatgcgg aaacactctg gcaggtgatg cgggataagc tcggggagga ataacagcac
    15061 cggcatggcc ggtgctggca tttatttttt gccgaacggc caccaccggc gggcaggttt
    15121 gtcctccggc agttcaggta ccggcacgtt aaaatagcgg ctgttatatt cccgcatcag
    15181 ctccgctttc agcttctcgt tcaccgcgct ttccccgtgc cgctcactca ccacgtcaat
    15241 catcgcgtta atctgctccg gtgagcactt cccggcatca accacctgca caccgttctc
    15301 gatggcgaac cgctccacct tgcgatagag gtaatcacac agcttcattc ctgtgggttt
    15361 gttccgttcc cattgcggat ttttaccagt gaaaaagtac gtggcttttt cgtcgctgtt
    15421 gagccgctcg tcatacatcc cgatggattt catcatcgcc agatgctggg cccggtcgac
    15481 aaaacagaaa acatacgccc ggtctgccag gcgagcacca ccatatcttc cagatgctcg
    15541 ctggtcggca tgatgcagcg ctcgccgttc cggtcctccg cgtcttcaat aaataccatg
    15601 tacagcgcca taatccctca ctccgttgtc ataaatttaa agcacgcaaa caaccgttca
    15661 cgatccagct ctgccgtttt gcgggcctcg ccggtctgtg ggttcacgat ttcatccacc
    15721 gacaggattg cccgctgcac cctgacctgc gtcgcccggt ccgggcagat gtaccagatt
    15781 tcatcgatgc cgttagcttt gcggttgaac agatacccgg acaccacttc ctgataccgg
    15841 cgacggctct tgacggtgcg ctccacctca aacgccaccg ttttaccgtc cagctccgcc
    15901 agggcgtccg gcactttcat gcctttaaga ctcagacggt gcagaatgcg ccagccggtg
    15961 gcccctctgg cttccatatc aaggcgcagg gattgcacgg ccagccggtg cggcagatgt
    16021 gctgccgaca cccttgacgg ctgaaacgga ataacatccg ccagcggttc gtcctcgtcg
    16081 aacgagaacg ccacgccatg cggcgtcagc ccccacacgc tgacctgacg gccgtccacc
    16141 ggatatttgg tccggaccag cagccctttc gccaccaggc tgtcgaggaa gcggtagacc
    16201 ggctgcaccg ccgcaatccc cagccgccgc gcaaccagct ccgccgtgga acacagctct
    16261 tcccgcaacc agcgcagggt cagccgggtt ttctccgcgt tccgcgcctg tcgtttcgcg
    16321 tggctgacgt tgtacagctc cagcgccatc agtaaatccc cgcaaaatca tcatccgctt
    16381 tcggcccgcc gccgtcggcc ggggccggaa ctccgccagg ggatcggttt tcgccagcac
    16441 cgggaaacgc tgcaacggga tttcccggcg ctcaacccgc agcggactgc tgaacgccat
    16501 ccgggccaca cccagcccgg tcatgaccgc gaacccgtcc ggcaggtgtt gcagggtgtt
    16561 cacgtcaaac agcggccgcg cctccttctg gatgaagctg tccccgctga tatgctccac
    16621 gttccccgcc tcccggctgg cacggcggcg ctccacgtcc accctgattt ccccggtctg
    16681 ccccgccgcc cactgcgcgg actccaggct ggccgcccgg taaaaccagc ggatcggcgt
    16741 gttatccagt accgtggttt tcacaaattc agcgggcaga tcctgcccgc actgcccgaa
    16801 atcgcccagc gactggtgcg cgagcaacag attgcagtcc cggctgcgca gcgtccccag
    16861 tgcgttcagt acatacttcg acagcagata tttaatttca tcgagcatca cgctgacgtg
    16921 tggccactcc cggaactcgt cccgcgcaat gatgatttgc gcgcagcggg caaacagcat
    16981 tttttgcaca cggatcaccg cctcgtcgtc catcgagccg ataacgtaca ggcagccgcc
    17041 gccgttgata atccccgcca catcgatgcc actgtccgtc tgcaggacgc tcaggtcagc
    17101 gacgttttcc agcctagtga tcaacccctt cacgtccttt ttcagggcct ccggcagcgc
    17161 gtacgccgcc gccagcacct gctgaatgtt tgccccctgc ggaaactgct ccgcaatcag
    17221 cttcgccgct ttctgctcgc tgatgcggta gtggtccgcc acgtcgccgg tctcgcccag
    17281 gttaagcccg gcaatcagca ggttttttca gcgcgtactg gtcgagatcg cggaacagat
    17341 tcagctgcgc cggtttcccc ggccgcagat ccagcagggt gaagtccgga cagtgcgccc
    17401 ggaagacgtg cggcgcccat gcgtcccctt tggggtcgaa gtacaccacc gcgtcccgaa
    17461 atcgcgtacg cagcgaatga gcgcgttggt ggccatcacg ctcttgccgc tcccgggcag
    17521 gccgaggatc tgaatgttgg tcttgcgcca ggtatcacgc ggaaccagca ccggcttgcc
    17581 ctgctcatcc ttaccagaaa caccgctgct cctgccgggc ctgctccgag gaaaaatcgg
    17641 ccagcgcatt aaccggtacc ggctccccga aatgcaggtg gcgcacgtcg gtcatctctc
    17701 ctgtccgctg gctgctgcgc cggctctcct gattcagttt cgcgttcacc gcctcgtcag
    17761 cagccgcaaa atgaccgtca agcagcagga acgccagcag ccgcgccaac acaatcccga
    17821 cagccagccc gcccgcgcac caggcaatcc cgaacaggtt agccggctgc agcaggtaat
    17881 aatctgcgtt tgcgtagagg tccggacgca ggacggtttc tccccagctc tcgataaaca
    17941 cggcgacaac cagcccccca gaagggccag accggccgcg ccggtcagcc agtacgcgta
    18001 gttccagaca tgtcgacgtg ccctgaccat ccgcccgggc gaatccagcg aggccagcac
    18061 cgaaaatggc gctggccgtt tattatcgcg cttatagcga tcggcatact cccgtcgctc
    18121 cttatgactc agccccacaa aacgcatccg tccggcccaa gttcagccag accgaaaaac
    18181 aggccgataa ctaggaaagc cccggccaga ccgtaatact cctggtacag ccagctgacc
    18241 cacggataaa tctgccgggc cagctccgga atgtgcactt ccaggcaagc gaatccgtat
    18301 taaacatgtt ctctctcctt cagacgatgg tttgccggcg tgatgtgcag ccccgctgca
    18361 caagccgcgg acatgcccca aggcatggcg gcggcggtca cgtccgtggt gattgcgttc
    18421 agctttcacc acggaggcca gcctctttcc gccccatgcg gaaaaggcgc agcccggagg
    18481 aacaacgagc acgccccagc gtgtgagagg aaaaggcggc accccagtgc ggtcttttcc
    18541 ggtgttccgg cccccgtcag agttcgccat agcgagcggc tgaccacccg caaaatcagg
    18601 agcagctttg ctgcttcgcc aggtgcgtcc agcaccgtgg atttttgtgg g
//
