LOCUS       NZ_CP050368             6812 bp    DNA     circular CON 16-MAY-2024
DEFINITION  Klebsiella pneumoniae strain 47733 plasmid p47733_OXA_181, complete
            sequence.
ACCESSION   NZ_CP050368
VERSION     NZ_CP050368.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14421539
            Assembly: GCF_011769725.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6812)
  AUTHORS   Chudejova,K., Kraftova,L., Mattioni Marchetti,V., Hrabak,J.,
            Papagiannitsis,C.C. and Bitar,I.
  TITLE     Genetic Plurality of OXA/NDM-Encoding Features Characterized From
            Enterobacterales Recovered From Czech Hospitals
  JOURNAL   Front Microbiol 12, 641415 (2021)
   PUBMED   33633720
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6812)
  AUTHORS   Bitar,i.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2020) Microbiology, Charles University in Prague,
            Alej Svobody 1655/76, Plzen 1 32300, Czech Republic
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Microbila Assembly v. SMRTL Link v.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 500.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011769725.1-RS_2024_05_16
            Annotation Date                   :: 05/16/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,842
            CDSs (total)                      :: 5,717
            Genes (coding)                    :: 5,542
            CDSs (with protein)               :: 5,542
            Genes (RNA)                       :: 125
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 175
            CDSs (without protein)            :: 175
            Pseudo Genes (ambiguous residues) :: 0 of 175
            Pseudo Genes (frameshifted)       :: 66 of 175
            Pseudo Genes (incomplete)         :: 113 of 175
            Pseudo Genes (internal stop)      :: 20 of 175
            Pseudo Genes (multiple problems)  :: 22 of 175
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050368.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6812
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="47733"
                     /isolation_source="Rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p47733_OXA_181"
                     /geo_loc_name="Czech Republic: Prague"
                     /lat_lon="50.08 N 14.36 E"
                     /collection_date="2018-12"
                     /collected_by="Charles University in Prague"
     gene            join(6784..6812,1..2869)
                     /locus_tag="HB636_RS29555"
                     /old_locus_tag="HB636_29570"
     CDS             join(6784..6812,1..2869)
                     /locus_tag="HB636_RS29555"
                     /old_locus_tag="HB636_29570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="WP_001553819.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            complement(3073..4020)
                     /locus_tag="HB636_RS29560"
                     /old_locus_tag="HB636_29575"
     CDS             complement(3073..4020)
                     /locus_tag="HB636_RS29560"
                     /old_locus_tag="HB636_29575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_015060053.1"
                     /translation="MRKCAQLELFRERLPRKPYYSDELTTGLRIADVARALGARYIQPN
                     GPTHRHWIVFDVDHAAATLSWDDVGAPAPNITVTNKANGHAHLIYGLDTPIRTAPDGNA
                     APLRYAAAIEAALREKLGADMGYSGLICKNPLHEHWLVQVWEPRLYDLAWLSDYLDLSS
                     YNGRKSLPEYGLGRNCTLFEKTRLWAYKAIRQGWPDYPEWLAACVDRASGYNAQFEQPL
                     PANEVRHTAKSIAKWTHQHLSPAGFREEQARRGAKGGKVSKGGGRPSNSGKDKSDLLPE
                     VLRLKAQGYTNRDIADDLQISPSTVSVYLKRDRP"
                     /name="replication initiation protein"
     gene            <4396..4548
                     /locus_tag="HB636_RS29565"
                     /old_locus_tag="HB636_29580"
                     /pseudo=""
     CDS             <4396..4548
                     /locus_tag="HB636_RS29565"
                     /old_locus_tag="HB636_29580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015059985.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EreA family erythromycin esterase"
                     /name="EreA family erythromycin esterase"
     gene            complement(4955..5752)
                     /locus_tag="HB636_RS29570"
                     /old_locus_tag="HB636_29585"
     CDS             complement(4955..5752)
                     /locus_tag="HB636_RS29570"
                     /old_locus_tag="HB636_29585"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011071128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OXA-48 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-181"
                     /protein_id="WP_015060052.1"
                     /translation="MRVLALSAVFLVASIIGMPAVAKEWQENKSWNAHFTEHKSQGVVV
                     LWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIAA
                     WNRDHDLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIR
                     ISATQQIAFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWW
                     VGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP"
                     /name="OXA-48 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-181"
     gene            complement(6084..6689)
                     /locus_tag="HB636_RS29575"
                     /old_locus_tag="HB636_29590"
     CDS             complement(6084..6689)
                     /locus_tag="HB636_RS29575"
                     /old_locus_tag="HB636_29590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509965.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGCAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     ARG             complement(4959..5752)
                     /name="blaOXA-181"
                     /gene="blaOXA-181"
                     /gene_name="OXA-48 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-181"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(3087..4008)
                     /name="rep_cluster_1195"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="81.974"
                     /coverage="98.0"
                     /evalue="0.0"
ORIGIN
        1 gcagcgagca gcgctgttcg atctgcccac ggacgaactg tcgctactga agttctacac
       61 gctgggcgat gatgacctgg aaaacattag gcagcgccgc agaccggaaa acaggattgg
      121 ctttgccctg caactttgtg ccttacgata tccgggccgt gcactggctc ctggtgagat
      181 gatcccgcgt gaagtccttt ccttcgtcgg tgctcagctt ggagttccgg ctgatgcgct
      241 tctcacttat gccacacggc gccaaacccg tcagcagcac atggacacgc tgcgcgaaat
      301 ttacggctac aagaccttca cgggccgtgg tgcccgtgat ctgcgggagt ggactttcgg
      361 ccaggccgaa gatgccagat caaacgagga tcttgctcat cgttttattg tgcggtgtcg
      421 ggaaacttcc accattctgc ccgcagtatc gacaatcgag cgcttgtgcg cggatgctct
      481 ggtcgccgct gagcggcgga ttgaaacgcg gattgcggaa aatttaacag cggatgttcg
      541 cgatcacctg gacaaacttc tgagtgaaat gctcgccggc aatatcagtc gtttcatctg
      601 gcttcgcaac ttcgaggttg gtaacaactc ggctgctgct aaccgtttgc tcgacaggct
      661 cgaatttctg cgtaccctga atatcaatca tagtgctttg gccagcatac ctgcccatcg
      721 cattgcccgg ctgcgtcggc agggtgaacg ctacttcacc gacggtttgc gtgacatcac
      781 ttcggaccgc cgctgggcga tccttgccgt ctgtgttgtg gagtgggaag cggcgattgc
      841 tgatgccata gtcgaaaccc atgacaggat cgtaggaaaa acctggcggg aagcgaagcg
      901 ccagcatgac gaaacaattt ccggctctaa agccacactc acggatacga tccgtacctt
      961 caccgcgctg ggagcttcgt tgcttgaggc ccgcagtgac ggaaccccgc tggagatggc
     1021 tgtcgccagt tcggttgcat gggaccggct cgctcaactg gtagcgacag ggactcaact
     1081 cagcaacacg ctagccgatg agcctcttgc atatgtcggg cagggatacc atcgctttcg
     1141 tcgttatgcg ccccgcatgt tgcgctgtct gaagctcgaa gccgcgccgg tcgccggacc
     1201 attggtagca gcagctttgt cgatcggaga gatgaaaggt gttgcatcgc cagaaaggcg
     1261 tttcctgcgg cccagctcca aatggaaccg tcatttacga gctcaggaaa aaggagatac
     1321 ccgtctttgg gaagtggcgg tactctttca cctccgggat gcttttcgtt ccggagatgt
     1381 ctggctcgct cattcgcgcc gctatggtga cctcaagcag gtactggtgc cgatgatcgc
     1441 ggcgcaggaa aatgcaaaac tggccgtgcc ttccaaccca caggattggc tggcagacag
     1501 aaaggcgcga ctcacgatcg ctcttaagcg gctggcccgg gctgcccgta acggcactat
     1561 tccgcacggt agcatagaag atggaacgtt gcggatcgac aggttgacag cagacgtgcc
     1621 ggatggtgcc gaggcactca tactggatct gtatcgccga atgccgtccg ttcggattac
     1681 cgacatgctg cttgaagttg atgcagccct tggtttcaca gatgcgttta cccatctgag
     1741 aaccggggct ccatgtcgcg accggatcgg tctgctcaac gtcctgctcg ctgaagggct
     1801 caatctgggc ctgcgtaaga tggcggaagc tacaaacacg catgattact ggcagctctc
     1861 acgccttgcc cgctggcatg ttgaaagcga agccatgaac caggcattgg caattgtggt
     1921 ggccgcgcag ggtaaactgc cgatgtcacg cgtctggggg atgggcacgt cagcatcgag
     1981 cgatggtcag tttttcccga cagcgcggca tggcgaagcc atgaacatgg tcaatgccaa
     2041 atatggttct gttcccggcc tcaaagcgta tactcacgta agcgaccagt tcgcgccatt
     2101 cgcttgtcag tcgatcccgg cgaccgtgag cgaggcaccg tatattctcg atggactact
     2161 gatgaacgag gtcggtcgcc atgttcgcga acagtatgcc gatacagcag gattcaccga
     2221 ccatttgttc ggagccagta gcctgctcgg ctacaatctc gttctgcgaa tcagggatct
     2281 gccatcgaag cggttgtacg tatttaatcc cgatacgacc cccagggagt tacgcaagtt
     2341 ggtaggtgga aaagcccggg aggatcttat cgttgcgaac tggcctgata ttttccgttg
     2401 tgccgcgacg atgaccgctg gcaaaatcag gcccagccaa ctcctgcgca agctcgcttc
     2461 ttacccacga caaaacaacc ttgcagttgc gcttcgtgaa gttggtcgta ttgaacggac
     2521 ccttttcatt attgagtgga tcctggatac ggacatgcag cggcgtgctc agatcggtct
     2581 taacaaggga gaggcccacc atgcgctcaa aaatgcgctc cgtatcggga ggcaggggga
     2641 aattcgcgat cgcacgacag aggggcagca ctaccgaatc gctgggctca atttattgac
     2701 tgcggtgatc atttactgga ataccgtcca tcttggtcat gccgtcacgg agcggcggaa
     2761 cgaagggttg gatgttcccc ctgaatttct tccccacata tccccattgg gctgggcgca
     2821 cattctactg actggcgaat atctttggcc caaggaaccg aaagcttagg gtgtcatttc
     2881 gccctcagcc ggaaccgacc cctggataac tgctgccgcc cacacccccc gaaaaaacag
     2941 gggggcgatg gacggacagg cgcagttgtc cacctcgcca aagatccgcg ctaaaaggat
     3001 tttttaaggc taaaagacaa gagcgcagga acccccctaa agggggctat tatctgataa
     3061 ggcttgtttc gatcacggac gatcacgctt taggtaaacg ctcaccgtac tgggggagat
     3121 ttgaagatcg tccgctatat cgcggttggt gtacccctga gccttaagcc gcagaacctc
     3181 cggcaataga tcggacttgt ccttaccgct attgctcggc cttccccctc ccttggatac
     3241 cttgccgccc ttcgcacctc tccgggcctg ctcctctctg aaccctgcgg ggcttaggtg
     3301 ctggtgcgtc catttggcaa tggacttggc cgtgtgccgg acttcgtttg cggggagcgg
     3361 ctgctcgaac tgggcgttat atcctgatgc ccggtcaaca caagcggcca accattcggg
     3421 gtaatccggc cagccctgcc ggatcgcttt ataggcccac aggcgcgttt tctcgaacag
     3481 ggtacagttt cgcccaagcc cgtactcagg aagcgatttg cggccattgt aggagctcag
     3541 atcgaggtaa tcggatagcc aggctaaatc gtagagccgg ggttcccata cctgcaccag
     3601 ccagtgctca tgcagggggt tcttgcagat cagcccggag tagcccatat ccgcccctaa
     3661 tttctcccgg agcgcggcct cgatggcggc ggcataccgc agaggggctg catttccatc
     3721 cggggcagtg cggatcggcg tatccagtcc gtagatcaga tgcgcgtggc cgttggcctt
     3781 gttcgtgacg gtaatgttag gggctggagc gcctacgtca tcccaagata acgtagcggc
     3841 tgcatggtct acgtcaaaaa cgatccagtg gcggtgcgtt ggcccgttcg gctggatgta
     3901 acgcgcacca agggcgcggg caacatccgc aatccgtagg cccgttgtaa gctcgtcgga
     3961 atagtagggt ttccggggca ggcgctcccg aaacagctca agctgtgcgc actttctcaa
     4021 gcaccaccgc gcttattggc ggcgtggggt tgtttggcat gatccatgtg atagacttct
     4081 cttgtgattc gtcacggccc ccgtttttcg cagctccgcc aagatgcaag cgataacggg
     4141 ggtttgtctt ttctggacaa tacgttacag caggcacatc ctagagagca acgttagttg
     4201 catgtaacct ttcaccctgg aacatatttc cacctccttc tgcttctgcg ctgttttgaa
     4261 ttgcttgatc tacgcctcta actaggtcga tccttgggat tgagtggcac cattgtcagt
     4321 gcaagaatac tgatccatat aagtctctct agtcggacaa caccaagtgt tgaagagatc
     4381 aaaaatcaac ctatatcgga ggattcatgt ctgacattga cagatgcccc catgaaagca
     4441 aagcgaatgc ggtcccaaag cgcctctgta gaaacgaatt tgagcgaggc atttgatgcc
     4501 atcgtctgcg tcccaagcgc cggcaaggac ggcctggttg acctatagta aaccggtaga
     4561 tgaaaatgat ggagaaccaa tatcagcgcc ttcttggact ttttcgtcaa acgctttagc
     4621 agccaagaaa gcctacaatc cttgatgggc taggcacttt atcgcagcgg cattcacctt
     4681 tactgacatc gccactcctt tattcacacc cccatgttga gtgaccatgg ccattgagat
     4741 aacaaaaaag cctagcaaat tggctaggct ttttacgttt aggaatgtga tgctaatgct
     4801 caggctgaaa gttaacgcgc ggagcttaag tcgattaggc ctgaccgatt aagtatgagc
     4861 cattaactac aagcgcatcg agcatcagca ttttgtccat atatctttac agcttatatg
     4921 acggctattt cacacaaata cgcgctaacc acttctaggg aataattttc tcctgtttga
     4981 gcacttcttt tgtgatggct tggcgcagcc ctaaaccatc cgatgtgggc atatccatat
     5041 tcatcgcaaa aaaccacaca ttatcatcaa gttcaaccca accaacccac cagccaatct
     5101 taggttcgat tctagtcgag tatcccgttt tagcccgaat aatatagtcg ccattggctt
     5161 cggtcagcat ggcttgtttc acgatgcgct gactacgctc agaaacgtgc agcttgttgt
     5221 gatacagctt gcgtaaaaaa gcgatttgct gggtagccga aatgcgaata ccaccatcga
     5281 gccaaaaact gtctacattg cccgagatat cctcattgcc ataatcgaag gcgtgcagca
     5341 ttttactcat acgtgcctca ccaatttggc gggcaaattc ttgataaaca ggcacaactg
     5401 agtacttcat cgcggtaatt aagtcatggt cacgattcca agcggcgata tcacgcgtct
     5461 gtccatccca cttaaagact tggtgttcat ccttaaccac gcccaaatcg agggcgatca
     5521 agctattggg aattttaaag gtagatgcgg gtaaaaatgc ttggttcgcc cgtttaagat
     5581 tattggtaaa tccttgctgc ttattctcat tccagagcac aactacgccc tgtgatttat
     5641 gttcagtaaa gtgagcattc caacttttgt tttcttgcca ttcctttgct accgctggca
     5701 ttccgataat cgatgccacc aaaaacacag ccgataaggc taatacacgc ataacgtccc
     5761 cttgcttaat gcaatatatc catacaaatt aagtgctaag cttatcattc tctgccctct
     5821 cattccctag caaactgctg accaattgtg gcaacaatca ggcacaagct ttaactatta
     5881 cctaaattcc acgtgtgttt tttattagct tcaaaaatca ctatttcacg aagaatttag
     5941 actgcttctc acacattgta acattattta caaccacctt tcaatcattt ttgataaatc
     6001 attgatttca tctttgctgc aatgatactt aataaactct gcaagttatc ggggtcggtt
     6061 ccggctgagg gcgaaatgac accctaagcg ttagctctgt gtcgttgcac gatgtcagcg
     6121 acggtattct tgctgatacc gagctcgcgt gcgatccagc gatagctgcg tccctcggcc
     6181 ctcatcgcaa ccaccttagg caaaagtcgg tctgattttg gtcgcactcc ggcctgacga
     6241 ccaagcctct taccacgtgc cttcgcaaca gcaaggcctg acttgacccg ctcgctgatg
     6301 agatcccgct caaactccgc aatgccggaa agaaacgtcg ccagcattcg tccatacggc
     6361 gacgaaagat cgaacgccat tccattcatg gctatcacgg aaaccttcca gttctccagt
     6421 tcacgtagcg tattgagcag atcgagcgtc gagcgccccc accgggaaag ctcagtgacc
     6481 aggattgcat caatttgtct ggactgggca agcgccagga ctttctttcg ctcggcccgg
     6541 tcgagtttag ttcctgaacc tgtttcctta aatattccca ccacgtcgta gccggcacag
     6601 ccggcgaagg ctcgcagatc aaattcctgg cgttcacaag actgatccgc tgttgaaacc
     6661 cggcagtaaa tggcggcacg atgtcccaat tgaaccctcc tggatttttg tatcggaacg
     6721 ccctgattta tatgggctgg ctgttgtcca aaacagacta tacttcaaaa gggacgaatt
     6781 tgtatgtcac gacgccatat tttcaccgaa cg
//
