LOCUS       NZ_CP050341             5596 bp    DNA     circular CON 28-NOV-2023
DEFINITION  Klebsiella pneumoniae strain ZRKP04 plasmid unnamed5, complete
            sequence.
ACCESSION   NZ_CP050341
VERSION     NZ_CP050341.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14411776
            Assembly: GCF_015238655.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5596)
  AUTHORS   Wang,C., Liu,Z., Sun,A., Li,L., Sun,L., Zhao,J., Li,B., Lu,B.,
            Liu,Y. and Cao,B.
  TITLE     In Vivo Selection of Meropenem Resistance among Ceftazidime-
            Avibactam-Resistant, Meropenem- Susceptible Klebsiella pneumoniae
            Isolate with KPC-33 Carbapenemase
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5596)
  AUTHORS   Wang,C., Liu,Z., Sun,A., Li,L., Sun,L., Zhao,J., Li,B., Lu,B.,
            Liu,Y. and Cao,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-MAR-2020) Bioinformatics center, GensKey Gene
            Technology Co. Ltd., Life Science Park Road, Beijing 102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 03-JAN-2020
            Assembly Method                   :: Unicycler v. version 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 111x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/28/2023 13:57:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,902
            CDSs (total)                      :: 5,780
            Genes (coding)                    :: 5,626
            CDSs (with protein)               :: 5,626
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 49 of 154
            Pseudo Genes (incomplete)         :: 108 of 154
            Pseudo Genes (internal stop)      :: 19 of 154
            Pseudo Genes (multiple problems)  :: 18 of 154
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050341.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5596
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="ZRKP04"
                     /isolation_source="bronchoalveolar lavage"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed5"
                     /geo_loc_name="China"
                     /lat_lon="39.98 N 116.43 E"
                     /collection_date="2019-11-23"
                     /collected_by="Laboratory of Clinical Microbiology and
                     Infectious Diseases, Department of Pulmonary and Critical
                     Care Medicine, China-Japan Friendship Hospital, Beijing, P.
                     R. China"
     gene            join(5277..5596,1..25)
                     /locus_tag="HB789_RS29245"
                     /old_locus_tag="HB789_30030"
     CDS             join(5277..5596,1..25)
                     /locus_tag="HB789_RS29245"
                     /old_locus_tag="HB789_30030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062955149.1"
                     /translation="MAVKRTRFLGIRVTDGEYQQLLERCNGRQLAVWMRETCLDTRPAR
                     SLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRVQVVAALMAIDAELERLRHA
                     VLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            234..>668
                     /locus_tag="HB789_RS29705"
                     /pseudo=""
     CDS             234..>668
                     /locus_tag="HB789_RS29705"
                     /inference="COORDINATES: protein motif:HMM:NF015397.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            703..1212
                     /locus_tag="HB789_RS29255"
                     /old_locus_tag="HB789_30035"
     CDS             703..1212
                     /locus_tag="HB789_RS29255"
                     /old_locus_tag="HB789_30035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            1219..1431
                     /locus_tag="HB789_RS29260"
                     /old_locus_tag="HB789_30040"
     CDS             1219..1431
                     /locus_tag="HB789_RS29260"
                     /old_locus_tag="HB789_30040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            2098..2322
                     /locus_tag="HB789_RS29265"
                     /old_locus_tag="HB789_30045"
     CDS             2098..2322
                     /locus_tag="HB789_RS29265"
                     /old_locus_tag="HB789_30045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            2306..2572
                     /locus_tag="HB789_RS29270"
                     /old_locus_tag="HB789_30050"
     CDS             2306..2572
                     /locus_tag="HB789_RS29270"
                     /old_locus_tag="HB789_30050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2642..2992)
                     /locus_tag="HB789_RS29275"
                     /old_locus_tag="HB789_30055"
     CDS             complement(2642..2992)
                     /locus_tag="HB789_RS29275"
                     /old_locus_tag="HB789_30055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197756.1"
                     /translation="MYWLIAFLAFIFPGRSFADGYTAYYRCNGTQEASLTVKDNKLSMV
                     VGLSKFNRQLDTYRFKEKGIEVVMQRAASDDNSEAIMSFIMPDVNNMTLLVKNNGYIIV
                     KTTCWLTKTDKQ"
                     /name="hypothetical protein"
     gene            complement(3058..3603)
                     /locus_tag="HB789_RS29280"
                     /old_locus_tag="HB789_30060"
     CDS             complement(3058..3603)
                     /locus_tag="HB789_RS29280"
                     /old_locus_tag="HB789_30060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            complement(3629..3955)
                     /locus_tag="HB789_RS29285"
                     /old_locus_tag="HB789_30065"
     CDS             complement(3629..3955)
                     /locus_tag="HB789_RS29285"
                     /old_locus_tag="HB789_30065"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     gene            complement(4313..4471)
                     /locus_tag="HB789_RS29815"
     CDS             complement(4313..4471)
                     /locus_tag="HB789_RS29815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     gene            5111..5287
                     /locus_tag="HB789_RS29290"
                     /old_locus_tag="HB789_30070"
     CDS             5111..5287
                     /locus_tag="HB789_RS29290"
                     /old_locus_tag="HB789_30070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     Typing          4946..5025
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="90.361"
                     /coverage="97.0"
                     /evalue="1.1100000000000001e-21"
     Typing          complement(4363..4760)
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          16..1547
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.804"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aaagggggca gacgatgatc gttaagtttc atccgcgagg gcgaggcggc ggtgccgggc
       61 cggtggatta tctgctgggg aaagaccgcc agcgcgacgg ggccatcgtc ctgcagggaa
      121 agccggagga ggtccgggag cttatcgacg cctcgcccta cgccaaaaag tacacctccg
      181 gcgtcctgtc ttttgctgaa caggatttac cgcccggcca gcgtgaaaag ctgatggcga
      241 gcttcgagcg ggttctgatg cccggactcg ataaagacca gtacagcgtg ctgtgggttg
      301 aacaccggga caaggggcgg ctggaactga attttctggt accgaacacg gaactgctga
      361 ccggcaggcg tctccagccg tactacgacc gggcagaccg tccgcgcatc gatgcgtggc
      421 agaccgtggt gaacgggcga ctggggctgc acgacccgaa cgcaccggag aaccggcgcg
      481 cgctggtgac gccatcttcg ttacccaaaa cgaagcagga agccgcagag gctattacgc
      541 ggggcttact ggccctcgcc tcgtcagggg agcttaaaac gcgtcaggac gtcactgagg
      601 cgctggaaag cgcaggtttt gaggtcgtgc gcaccacaaa gagcagcatc agcattgccg
      661 acccggacgg agggcgaaac atccgactta agggagccat ctatgaacag tcttttaacg
      721 ctggcgaagg acttagagca gaaatcgaaa gcgcagcagc agagtaccgg cgaaatgctg
      781 aaagccgcat tcagcgagca cgagaagtct gtcagagcgg aactgagcga aagcgggaag
      841 agaatcagcg ccgccatccg cgcccacgag cagggtatga gcgcggccat gcagtcgaac
      901 cgcctgagcg tgatgcgtat ggtcgggcgg acatggctga ccatcacgat ggtgtcagga
      961 ctgctgttcg ccagcctgag cggggtgttg tggtatcagg ggagcttgat agcgtcaaat
     1021 ctggccgaaa tcgaccggca gaacgcagcg ctgtcgaagc tgaacgcgaa gacctggggc
     1081 gtgacgtacc tggaagacag caacggacgt tttctggtgc tgccgaaggg gacggccgta
     1141 gacaggacgc agagctggac ggtcgggaac gggcggtcga agcagaacgc gctgagactg
     1201 gtgaaggagt aagtgccgat gaccgagctg gaaaaacagt tgctgagcgc attagagcag
     1261 ctacagcagg actactcgaa aaggctggac gagtgggaga gcgccttcgg ggaatggcgg
     1321 aaaatgtcag ggcttatgca acgggagaac gcggcgctga gcgagcgcgt gacgcgcttg
     1381 agtcagcagg tggaacgctt gagcgggcaa ctgcagcgtt tgagccggta gtgcagcgtc
     1441 atgagatggc cgtggccgca gaacgggcgc acgagcaacg gcagcacgaa aaggaactga
     1501 cggaagcgcg ttcccggcag cgaagctatg acggtccgtc gctgggctga aatgcaggaa
     1561 aacagggttc tcatcgggca tttacgctga aaccggatgt cattcacctg gctgcatggc
     1621 tatgcagcca ggtaaaattt atctgtcgcg aacggggcgg tttatcgggt ggtttgttgc
     1681 cggttttacc tgactgccac cccgttcgcg gcgaacccgt ccggggcggt gcgggcaacg
     1741 ggtgttatgt ttaatcagcg tgaacggcag atacaaaaaa gccccggagg gcttttaact
     1801 actgacttat ttttttgaag atttgctggg tttcaatttg tcagtatttc ccggcgtttt
     1861 tttattgtca cgctggcgtt tatcaggttc ccctgttgaa tcggcaattc gtttcggacc
     1921 cggcttaaga cccataatcg ttatcctttc aatagttaag aggaaagccc tcaagctaga
     1981 tatattgacc gcgttacgga ttatcaagag gggctaacaa gattattttt tgttctttta
     2041 ggttgattgt ggtactgttg atatacatgt atagcaaatg gtgttcggga ggtttatatg
     2101 cttgctatcc ggttatctga tgagattgag tcccgtctgg actcgctggc gaagcaaacc
     2161 ggcagaacaa agacgtttta tgcgcgggaa gcaatactgg cgcatctgga agacctggag
     2221 gattattatc tttcagcaga aactgctgca cgcgttcgcc gtggtgatga agcagtgcat
     2281 tcgtctgaag acgtgaggaa gtcacttggt ctggacgatt aactattccg atcgggcgct
     2341 caaatcgtta cgcaagatgg acaaacagaa cgcacgacgg attgtggatt ttatgagttt
     2401 acgcattgca gttgctgccg atcctcgcca gtcagggaag ccgctcaaag gtgagctggg
     2461 cgagttctgg cgctatcggg tgggagatta tcgcgttctg tgtgagatcc gagatgacga
     2521 gcttgttatc cttgccgcca cgattggaca tcgccgcgaa gtttacgact gaagcccgct
     2581 atgcgggctt ttttgatgcc gacaacaggt attatggtaa atactcgact aactacgtgt
     2641 tctactgttt gtcggtttta gttaaccagc aggttgtctt aacgataatg tagccgttat
     2701 ttttaactaa taaggtcata ttgttaacgt caggcataat aaaagacatt atggcctcag
     2761 agttatcatc agaagcagct ctctgcatta ctacttcgat tcccttttct ttgaatctat
     2821 aagtatccag ttgcctatta aacttagaaa gacctacaac catacttagt ttgttatctt
     2881 taacagtaag agatgcttcc tgagtaccat tacatcggta gtaagcggtg taaccgtcag
     2941 caaaagatcg accggggaat ataaatgcta ggaacgcaat taaccaatac atagttgaga
     3001 atcttggtat tacacatttc actatcctct ctttcatttt tcgttcacca tactttgtta
     3061 tctgattttt aatttttcta ttttataaac caagtctcta ccaaaaaggc gaaaattatc
     3121 ctcaaataat aataattgtt taagaacatc catgaaagca gctgcttcac cctcagttat
     3181 gggagctact ctatataaca tataacctga gttaagggtt tcttttatac tttcttcaat
     3241 gctcattata aatattagtg gattatcatt tttcttcccc catgggtttc taattaatcc
     3301 ttcgatgtac tcaggtcctt tgcgtcctat tgcctgcgca atatttttta tttcatctgc
     3361 gtgagggctt tgttgtacag ctttgtttat gcctgcttga gtgattttca gagactctac
     3421 accgtgtatg ttgtatgaga taaaatgtaa taaattaaga tgcaatgcaa ttaatccatt
     3481 tttgtttaca tctgagtatt tggataaaaa acgtaatgaa gtgttaactc tcccttgaag
     3541 cctaacaatt gggagtgctg ccttgtatat ttccttctcc gttaaatacc gtttaaaaaa
     3601 cataattctc cgcctccgta tagcgtgcct attttatttc gtcgtaaaac ttagctctga
     3661 aatattcctt tagaaccatc atgtcattaa taattgaatc tatctcatcc attttttctt
     3721 ggtattcttt taatggtgaa gggagcggta actcaatatt tgaaaagtga ttggcgagat
     3781 agggatcaag gtttctcatc cattcaggct tttcgccaat gcgttcttca actgaaagtg
     3841 aacctgataa tctctggtta ataagatcac ttagactcat tttggtttta ttcgaaagcc
     3901 gttgtaagga ttgctttaat cctatatcta gcatgatatt tgttctttct ctcattaccc
     3961 ccccttgcta ttgcgttttt tgttgcgcac aaagctacca ttgcgcatta agaaacgcaa
     4021 taaaaaagga gggagggagt ggtttgtaca tgatgtgcag tgcgctgagg gcatcagtgg
     4081 cgggtgtttt tccgtgggat ggatggagct ccggggataa cagaactgac gatcatttaa
     4141 aggatcttct tgagatcctt tttttctgcg cgtaatctct tgcactgtaa acgaaaaaac
     4201 cgcctgggga ggcggtttga tcgaaggtta agtcagttgg ggaactgctt aaccgggtaa
     4261 ctgggtatac gagaccgcag ataccaaaac tgttctttca gtgtagccgc agttaggcac
     4321 ccacttcaag acctctcaat atctctctcg tatatatcca gttaccaatg gctgctgcca
     4381 gtggcgtttt tgcgtgtccg tccgggttgg actcaagatg atagttaccg gaaagggcgc
     4441 agcagtcggg ctgaacgggg ggttcgtgca tacagcccag cttggagcga acgacctaaa
     4501 ccgagccgag ataccagcag cgtgagctat gagaaagcgc cacgcttccc gaaagggaaa
     4561 aaggcggaac aggtatccgg taaacggcag ggtcggaaca ggagagcgca cgagggagcc
     4621 gccggagaga aatcaccggc atctttaagt cctgtcgggt ttcgtcctcc tctgacttga
     4681 gcgtccattt ctgtgatgct cgtcagggga ggcggagcct atggaaaaac ggcaacgccg
     4741 catccttttc tccggccctt tctgatttga gcgcctttgc tttatcccgt tatccgtgag
     4801 tcggtcacgc ccgccgcagc cgaacggcag gagcgcagct accgagtgag cgaggaggcg
     4861 tcatttcatc tgtccgtgca tggtattgcg gacgctcctg agccacatat cacacctgcc
     4921 acatgaggca ctttcatgaa tcgtgctctc atgccaacat agtaagccag tatacacagc
     4981 gtaaacgctg tgactggttc agggctgcgc cccgaaaccc gctaacacca ctgacgcgct
     5041 ggcgcttgtc caacgccgga gcgacccgga aaacttttcc gtgccgtccg gcgtttgcga
     5101 aggagggata atgcagaagc cgaagaagaa gccgctcgtc gtaaaaaaaa gatcctggca
     5161 tccggcagtg atggcaaatc tgatgcgtca ggcacaggag gaagattacc gccgggagca
     5221 gatggcagag cttgagcgtt cagcccggtc acattttgcg gatatcggag gagaggatgg
     5281 cggttaagcg tacccgtttt ttaggtatcc gggtgaccga tggggagtac cagcagctgc
     5341 tggagcgctg caatggaagg caactggcgg tgtggatgcg ggaaacctgt ctcgatacgc
     5401 gcccggcgcg gtcgttgcgg ctgccgtcca tcgatccggt tttgctgcgc cagcttgccg
     5461 ggatggggaa caacctcaac cagatcgccc ggaaaattaa cggcggccag tggtcaggcg
     5521 ctgaccgggt tcaggtggtg gccgcgctga tggccattga tgccgaactc gagcggctgc
     5581 ggcatgccgt gctgga
//
