LOCUS       NZ_CP050049            27018 bp    DNA     circular CON 14-JUN-2023
DEFINITION  Escherichia coli strain 90-1 plasmid pCD90-1-2, complete sequence.
ACCESSION   NZ_CP050049
VERSION     NZ_CP050049.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14278032
            Assembly: GCF_014075335.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27018)
  AUTHORS   Lv,H. and Cui,Q.
  TITLE     Identification of novel plasmids containing the tigecycline
            resistance gene tet(X4) in Escherichia coli isolated from retail
            chicken meat
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27018)
  AUTHORS   Lv,H. and Cui,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2020) College of Veterinary Medicine, China
            Agricutural University, Yuanmingyuan West Road, Beijing 100000,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.3.4
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/14/2023 05:05:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,777
            CDSs (total)                      :: 4,659
            Genes (coding)                    :: 4,513
            CDSs (with protein)               :: 4,513
            Genes (RNA)                       :: 118
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 53 of 146
            Pseudo Genes (incomplete)         :: 83 of 146
            Pseudo Genes (internal stop)      :: 33 of 146
            Pseudo Genes (multiple problems)  :: 23 of 146
            Pseudo Genes (short protein)      :: 3 of 146
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050049.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27018
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="90-1"
                     /host="broiler chicken"
                     /db_xref="taxon:562"
                     /plasmid="pCD90-1-2"
                     /geo_loc_name="China:Sichuan"
                     /collection_date="2019-05-15"
     gene            <2..712
                     /locus_tag="G9P52_RS23520"
                     /old_locus_tag="G9P52_23520"
                     /pseudo=""
     CDS             <2..712
                     /locus_tag="G9P52_RS23520"
                     /old_locus_tag="G9P52_23520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="APH(6)-I family aminoglycoside
                     O-phosphotransferase"
                     /name="APH(6)-I family aminoglycoside O-phosphotransferase"
     gene            complement(<818..1720)
                     /locus_tag="G9P52_RS23525"
                     /old_locus_tag="G9P52_23530"
                     /pseudo=""
     CDS             complement(<818..1720)
                     /locus_tag="G9P52_RS23525"
                     /old_locus_tag="G9P52_23530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS903B family transposase"
                     /name="IS5-like element IS903B family transposase"
     gene            2301..2687
                     /gene="stbA"
                     /locus_tag="G9P52_RS23530"
                     /old_locus_tag="G9P52_23535"
     CDS             2301..2687
                     /gene="stbA"
                     /locus_tag="G9P52_RS23530"
                     /old_locus_tag="G9P52_23535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006796897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbA"
                     /protein_id="WP_001039464.1"
                     /translation="MNKPADLKPRNLSAAVRLRLNEIENWLDRGLTRHEIAEILDSEYS
                     FSVTAKGLEMALYRTRQNRKNVLHNTHDKSSAKGAAESVLHNTQPSEPEVQESKKAESP
                     GIIDKEFFKKIGENFDPKKFNKKF"
                     /name="stbA"
     gene            complement(2827..3795)
                     /locus_tag="G9P52_RS23535"
                     /old_locus_tag="G9P52_23545"
     CDS             complement(2827..3795)
                     /locus_tag="G9P52_RS23535"
                     /old_locus_tag="G9P52_23545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="WP_030005799.1"
                     /translation="MKDQITHLPDNADHSVAKQKFKITNWPTYNKALINRGSITFWLDD
                     EAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFTLMNVPLR
                     CPDYTSVSKRAKSVNVSFKTFTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRK
                     LHLAVDSNTHEIICANLSLNNVTDSEAFPGLIRQTHRKIRAASADGAYDTQLCHDELRR
                     KKISALIPPRKGAGYWPGEYADRNRAVANQRLTGSNARWKWTTDYNRRSIAETAMYRVK
                     QLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA"
                     /name="IS5 family transposase"
     gene            complement(4643..>4951)
                     /locus_tag="G9P52_RS23540"
                     /old_locus_tag="G9P52_23550"
                     /pseudo=""
     CDS             complement(4643..>4951)
                     /locus_tag="G9P52_RS23540"
                     /old_locus_tag="G9P52_23550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561120.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            complement(4961..5658)
                     /locus_tag="G9P52_RS23545"
                     /old_locus_tag="G9P52_23555"
     CDS             complement(join(4961..5409,5409..5658))
                     /locus_tag="G9P52_RS23545"
                     /old_locus_tag="G9P52_23555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /ribosomal_slippage=""
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1A family transposase"
                     /protein_id="WP_103215986.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1A family transposase"
     gene            complement(5733..6014)
                     /locus_tag="G9P52_RS23550"
                     /old_locus_tag="G9P52_23560"
     CDS             complement(5733..6014)
                     /locus_tag="G9P52_RS23550"
                     /old_locus_tag="G9P52_23560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000220560.1"
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLH
                     GHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADLR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(6004..6255)
                     /locus_tag="G9P52_RS23555"
                     /old_locus_tag="G9P52_23565"
     CDS             complement(6004..6255)
                     /locus_tag="G9P52_RS23555"
                     /old_locus_tag="G9P52_23565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="WP_000121743.1"
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL"
                     /name="plasmid stabilization protein"
     gene            7489..8325
                     /locus_tag="G9P52_RS23560"
                     /old_locus_tag="G9P52_23570"
     CDS             7489..8325
                     /locus_tag="G9P52_RS23560"
                     /old_locus_tag="G9P52_23570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050932.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_001050931.1"
                     /translation="MNLLSVTKKTKIRHRNEINSTFSSLPLSARRILFMAMAQIDSREE
                     LSEGATFRITAREYAFIADIDVTGAYRQLKEGAEELQASVIRIPRNQLLTPQGNQSSGH
                     TKKRGKLPSDAVRLMNLTAFCDYVESEGYIDIAFSHVIEPYITMLKDSYTTQVLISSVR
                     LADQNSNMLYQFIRKQYSSGKKTFFDIEVDVLKDELELFRIDNGEKVYLYQNFKDFNKV
                     FLQKNIEKINQYTEINHLEVKIVERVARRASKLRFSYKIDKESEGLDIRIPYGFRG"
                     /name="RepB family plasmid replication initiator protein"
     gene            8365..8811
                     /locus_tag="G9P52_RS23565"
                     /old_locus_tag="G9P52_23575"
                     /pseudo=""
     CDS             8365..8811
                     /locus_tag="G9P52_RS23565"
                     /old_locus_tag="G9P52_23575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            8948..9304
                     /gene="ddp1"
                     /locus_tag="G9P52_RS23570"
                     /old_locus_tag="G9P52_23580"
     CDS             8948..9304
                     /gene="ddp1"
                     /locus_tag="G9P52_RS23570"
                     /old_locus_tag="G9P52_23580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_000456533.1"
                     /translation="MEYQVREFINEKYTKAVNILKDNLKENYHVFYGVRLIEILFPASE
                     YGTDAFFKEFELINSVILPLVIFDLTQRKPMMIISFDKILDASLLEGTNIVVLECITLA
                     DLLTNDNIDFLYKS"
                     /name="ddp1"
     gene            complement(9301..10278)
                     /locus_tag="G9P52_RS23575"
                     /old_locus_tag="G9P52_23585"
     CDS             complement(9301..10278)
                     /locus_tag="G9P52_RS23575"
                     /old_locus_tag="G9P52_23585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6685 family protein"
                     /protein_id="WP_024245156.1"
                     /translation="MRYLTELICDLYRLTDHHKLTTATFKNLADIKLFKPTADADTILQ
                     LENIFSEYSLRYIDKDLAEILSNLITTDKKHSLDFDFNKIQSLTDSKSFGCGWSKVING
                     SWFKDLYSWGEGMYPAENLKAENILDWKDNIWHIEHEGFPPRPPINVKYYSWFDRYVAS
                     NSGGSHHAAMVVYQSVRDGLEYKREAVIKQLSIDPGTVEILDKNYYSFIFQIKTLNKET
                     RIYTSEYEFTDALKDFGQNRHTILKPVNYVSNIKLVFIPKDALKTNSETFRNWFHSAIS
                     CGKIISLPDYLKNPAHYHTLHYSHEVDSITLGDPSRKFKLKGDS"
                     /name="DUF6685 family protein"
     gene            complement(10303..10584)
                     /locus_tag="G9P52_RS23580"
                     /old_locus_tag="G9P52_23590"
     CDS             complement(10303..10584)
                     /locus_tag="G9P52_RS23580"
                     /old_locus_tag="G9P52_23590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001185482.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVVGKPKLMNFRL
                     SAHFEDILEAEAIRTGQSKTTVLKAALAMYNSQDENIKNHWLLESAKF"
                     /name="hypothetical protein"
     gene            complement(10682..11344)
                     /locus_tag="G9P52_RS23585"
                     /old_locus_tag="G9P52_23595"
     CDS             complement(10682..11344)
                     /locus_tag="G9P52_RS23585"
                     /old_locus_tag="G9P52_23595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516402.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHDL
                     LSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVSDI
                     VVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDLDKL
                     LRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIGIL"
                     /name="division plane positioning ATPase MipZ"
     gene            11725..12363
                     /locus_tag="G9P52_RS23590"
                     /old_locus_tag="G9P52_23600"
     CDS             11725..12363
                     /locus_tag="G9P52_RS23590"
                     /old_locus_tag="G9P52_23600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549893.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_024245155.1"
                     /translation="MTQTVPKGFVRAYLRASTSEQDASRALAAIDSFAEERGLNICNYY
                     IENESGSRLDRPELFRLLKDCRHNDILLIEDVDRLSRLTGEDWNSLKKLIRQKDIRVMA
                     INVPTTWIASGSHDFDSRMFAAINDMLLDMLAAVARRDYEQRRERQRQGISKAQKEGRY
                     KGRQANKERYDAINRLLDSGSSWSQVQKIMACSRGTISSAVKSRKLNAI"
                     /name="recombinase family protein"
     gene            complement(12462..>13280)
                     /locus_tag="G9P52_RS23595"
                     /old_locus_tag="G9P52_23605"
                     /pseudo=""
     CDS             complement(12462..>13280)
                     /locus_tag="G9P52_RS23595"
                     /old_locus_tag="G9P52_23605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            13341..14045
                     /locus_tag="G9P52_RS23600"
                     /old_locus_tag="G9P52_23610"
     CDS             13341..14045
                     /locus_tag="G9P52_RS23600"
                     /old_locus_tag="G9P52_23610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <14097..14366
                     /locus_tag="G9P52_RS23605"
                     /old_locus_tag="G9P52_23615"
                     /pseudo=""
     CDS             <14097..14366
                     /locus_tag="G9P52_RS23605"
                     /old_locus_tag="G9P52_23615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492336.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            14495..15358
                     /locus_tag="G9P52_RS23610"
                     /old_locus_tag="G9P52_23620"
     CDS             14495..15358
                     /locus_tag="G9P52_RS23610"
                     /old_locus_tag="G9P52_23620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_000612791.1"
                     /translation="MIPNSENKRVWFITGASKGLGYAFTCAALKAGDKVVAVARTIDNL
                     AKLEETYQESLLPLNLDVTDREAVFSTVETAVKHFGRLDIVVNNAGIMTMGMIEELNES
                     DARKLMDTNFFGALWVCQAVMPYLRSQRSGHIIQITSIGAIISGPMSGIYSASKFALEG
                     MSEALAKEAEHFGVKLTMVEPGGYWTDLYTSMSYSNPLDSYGTLRDELAKQYSEDSVDS
                     DPSLAAEALMKLVASNNPPLRLILGSMVYDLAMDTLKARMATWEEWEAVSRASEKAIPA
                     PERYGV"
                     /name="SDR family oxidoreductase"
     gene            15396..15641
                     /locus_tag="G9P52_RS23615"
                     /old_locus_tag="G9P52_23625"
     CDS             15396..15641
                     /locus_tag="G9P52_RS23615"
                     /old_locus_tag="G9P52_23625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001354008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="WP_001354008.1"
                     /translation="MKIEIMEYNPDWTKNFEEEKIKLLHFFGSHAVAIEHIGSTAIPNQ
                     RAKPVIDIFIGVSPFAELPFISAFLMQRSITTLRQI"
                     /name="GrpB family protein"
     gene            16110..16901
                     /gene="sul3"
                     /locus_tag="G9P52_RS23620"
                     /old_locus_tag="G9P52_23630"
     ARG             16111..16898
                     /name="sul3"
                     /gene="sul3"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul3"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(17159..18019)
                     /locus_tag="G9P52_RS23625"
                     /old_locus_tag="G9P52_23635"
     CDS             complement(17159..18019)
                     /locus_tag="G9P52_RS23625"
                     /old_locus_tag="G9P52_23635"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     gene            complement(18202..18759)
                     /locus_tag="G9P52_RS23630"
                     /old_locus_tag="G9P52_23640"
     CDS             complement(18202..18759)
                     /locus_tag="G9P52_RS23630"
                     /old_locus_tag="G9P52_23640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001235713.1"
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            18923..21928
                     /locus_tag="G9P52_RS23635"
                     /old_locus_tag="G9P52_23645"
     CDS             18923..21928
                     /locus_tag="G9P52_RS23635"
                     /old_locus_tag="G9P52_23645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143760.1"
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQVSVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGTLGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            complement(<21971..22986)
                     /locus_tag="G9P52_RS23640"
                     /old_locus_tag="G9P52_23650"
                     /pseudo=""
     CDS             complement(<21971..22986)
                     /locus_tag="G9P52_RS23640"
                     /old_locus_tag="G9P52_23650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612175.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            23381..24037
                     /locus_tag="G9P52_RS23645"
                     /old_locus_tag="G9P52_23655"
     CDS             23381..24037
                     /locus_tag="G9P52_RS23645"
                     /old_locus_tag="G9P52_23655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrS1"
                     /protein_id="WP_001516695.1"
                     /translation="METYNHTYRHHNFSHKDLSDLTFTACTFIRSDFRRANLRDTTFVN
                     CKFIEQGDIEGCHFDVADLRDASFQQCQLAMANFSNANCYGIEFRACDLKGANFSRTNF
                     AHQVSNRMYFCSAFISGCNLSYANMERVCLEKCELFENRWIGTNLAGASLKESDLSRGV
                     FSEDVWGQFSLQGANLCHAELDGLDPRKVDTSGIKIAAWQQELILEALGIVVYPD"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrS1"
     gene            complement(24356..>24784)
                     /locus_tag="G9P52_RS23650"
                     /old_locus_tag="G9P52_23660"
                     /pseudo=""
     CDS             complement(24356..>24784)
                     /locus_tag="G9P52_RS23650"
                     /old_locus_tag="G9P52_23660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017412822.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            complement(24817..26145)
                     /locus_tag="G9P52_RS23655"
                     /old_locus_tag="G9P52_23665"
     CDS             complement(24817..26145)
                     /locus_tag="G9P52_RS23655"
                     /old_locus_tag="G9P52_23665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001589371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISKra4-like element ISKpn19 family transposase"
                     /protein_id="WP_226201773.1"
                     /translation="MTIQKSGETRNDIGLSVSESKLLLNTVQQSVVQLQADEYTQHHIR
                     CPHCLAARRIKGKQKIRYRTLFGVIPVSGLRVYRCRCEESDTKTVSLLSDWAGDYSHPA
                     LKYIETRWASMISYEMTTRLLKDILPVGHSLNASTVRNHLCQVAQRLDAEAEAHSGFLS
                     GCPRDWGNLPRPGKPLVVGIDGGYVRDRDDKKRNFEIIAGKSFSVGAPADTRRFGFVQK
                     DDCHPERRLMTHLSAQGMQANQQIFFLSDGADNLRDLQFGMYPESTHVLDWFHITMRLK
                     VLMQYARGLLVSDPEAGSKVLALLESIKRYLWHGNVVAALEHIDNCVMYCDDPELSYPS
                     LKSLQKHLDEMYTYIRNNKMMIPNYGEMRRYGEPVSTAFVESTINEVIARRMAKKQQMQ
                     WSRKGAHYLLQTRTAVLNNELQDKFVCWYPGFQSDGKGPAMAA"
                     /name="ISKra4-like element ISKpn19 family transposase"
     gene            26262..26966
                     /locus_tag="G9P52_RS23660"
                     /old_locus_tag="G9P52_23670"
     CDS             26262..26966
                     /locus_tag="G9P52_RS23660"
                     /old_locus_tag="G9P52_23670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     ARG             23382..24034
                     /name="qnrS1"
                     /gene="qnrS1"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrS1"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(17163..18019)
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             14110..14366
                     /name="mef(B)"
                     /gene="mef(B)"
                     /gene_name="major facilitator superfamily (MFS) antibiotic
                     efflux pump"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="20.78"
     ARG             3..712
                     /name="APH(6)-Id"
                     /gene="APH(6)-Id"
                     /gene_name="APH(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.58"
                     /coverage="84.89"
     Typing          complement(1818..2075)
                     /name="MOBF"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.273"
                     /coverage="96.0"
                     /evalue="7.34e-49"
     Typing          8366..8811
                     /name="IncX1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.21"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 attgaaacct atagaagaca ttgctgatga actgcgcggg gccgactatc tggtatggcg
       61 caatgggagg ggagcagtcc ggttgctcgg tcgtgagaac aatctgatgt tgctcgaata
      121 tgccggggag cgaatgctct ctcacatcgt tgccgagcac ggcgactacc aggcgaccga
      181 aattgcagcg gaactaatgg cgaagctgta tgccgcatct gaggaacccc tgccttctgc
      241 ccttctcccg atccgggatc gctttgcagc tttgtttcag cgggcgcgcg atgatcaaaa
      301 cgcaggttgt caaactgact acgtccacgc ggcgattata gccgatcaaa tgatgagcaa
      361 tgcctcggaa ctgcgtgggc tacatggcga tctgcatcat gaaaacatca tgttctccag
      421 tcgcggctgg ctggtgatag atcccgtcgg tctggtcggt gaagtgggct ttggcgccgc
      481 caatatgttc tacgatccgg ctgacagaga cgacctttgt ctcgatccta gacgcattgc
      541 acagatggcg gacgcattct ctcgtgcgct ggacgtcgat ccgcgtcgcc tgctcgacca
      601 ggcgtacgct tatgggtgcc tttccgcagc ttggaacgcg gatggagaag aggagcaacg
      661 cgatctagct atcgcggccg cgatcaagca ggtgcgacag acgtcatact agatatcaag
      721 cgacttctcc tatcccctgg gaacacatca atcttaccgg agaatatcgt tggccaaagc
      781 cttagcgtag gatttcgccc tctcccgcaa acgaccccat agcctccgca acctgaccat
      841 cgtagtcacg cagcgtcagt gaacccccga acagctgttt tacccggtac atcgccgttt
      901 ccgctatcga gcgacggttg taatctgttg tccatttcca ccgcgcatta ctcccggtca
      961 ttcgctgatt agccactgca cggttacggt ctgcatattc accgggccag taacccgcac
     1021 cttttcgggg agggataagc gcgctgattt tcttacgccg cagttcatcg tgacagagcc
     1081 gggtgtcgta agcgccgtct gccgatgctg ccctgatttt tctgtgagtc tgccggataa
     1141 gacccgggaa ggcttctgag tccgtcacat tgttcagcga caggtctgca cagatgattt
     1201 catgtgtgtt gctgtcaact gccagatgca actttcgcca tatacgacgg cgttcctggc
     1261 catgcttttt gactttccac tcgccttcac caaagacctt cagcccggtg gaatcaatca
     1321 ccagatgcgc gatttcaccc cgggtgaacg ttttgaaact gacgttaacc gactttgccc
     1381 gcctgctgac acagctgtaa tccgggcagc gtagcggaac gttcatcaga gaaaaaatgg
     1441 aatcaataaa gccctgcgca gcgcgcaggg tcagcctgaa tacgcgttta atgaccagca
     1501 cagtcgtgat ggcaaggtca gaatagcgct gaggtctgcc tcgtgaagaa ggtgttgctg
     1561 actcatacca ggcctgaata gcttcatcat ccagccagaa agttatggag ccacggttga
     1621 tgagggcttt attgtaggtg ggccagttgg ttattttgaa cttttgcttt gccacggaac
     1681 ggtctgcgtt gtcgggaaga tgcgtgatct gatccttcaa ctcagcaaaa gttcgattta
     1741 ttcaacaaag cccattcagt cctcaatttg tgcatttttt aaacgaaaaa agggtgtcta
     1801 atacggtgaa atcatagtat taccaaagta ataaataaaa agttatttaa atcagtaatt
     1861 tagatttgat ttgtaatacc tgggtaatac cgcagcatgg ctaaattttg ttttttttct
     1921 tttaaatcag tgcgatagcg tgatttatca cgctgcgtta ggtgtatagc aggttaaggg
     1981 ataaaaaatc atcttttttt ggtagggcga tctccgtagg ttaaggggca tttggctaaa
     2041 aagcgtccta ttctttgatg gtcatgcttg catgaccatc tgagcaacca aaaactacag
     2101 ataaactaca gataaactac aaaaaacgtt ttgccttagt gttgtaagac tacaaataga
     2161 ctacaataaa actacaaata aactacaaaa aacgtgacag actacaaata gactacaata
     2221 aaactacaga taaactacaa aactcgattg accccttctt acgagtgttg tagagtcatt
     2281 ttcatacaac ggagggggtt atgaataaac cagcagatct gaaaccccgc aacttatcgg
     2341 ctgctgtcag attgcgccta aatgaaatcg agaactggct ggacagaggg ctaacgcggc
     2401 atgaaattgc tgaaatcctc gacagcgaat acagcttttc ggtaacagcc aaagggcttg
     2461 agatggcact gtatagaacg cggcaaaacc gaaaaaatgt attgcacaat acgcatgata
     2521 agagtagcgc gaagggtgca gcggaaagtg tattgcacaa tacacaaccg tctgagcctg
     2581 aagtgcagga aagtaaaaaa gcagagagtc ccggcattat tgataaagaa ttcttcaaga
     2641 aaatcggtga gaatttcgac cctaagaagt tcaacaaaaa attctgaggt gatttatgaa
     2701 agtagcggta attaattaca gtggcagtgt tcgtaaaacc ttaatttcat cttacctgtt
     2761 agccccgcgc ggctttgttg aataaatcag atttcgggta agtctccccc gtagcgggtt
     2821 gtgttttcag gcaatacgca cgctttcagg catacctgct ttcgtcattt tgttcagcgc
     2881 tcgtaccagg gccatagcct ctgcaacctg accatcgtag tcacgcagtg tcagtgaacc
     2941 tccgaacagc tgttttaccc ggtacatcgc cgtttccgct atcgagcgac ggttgtaatc
     3001 tgttgtccat ttccaccgcg cattactccc ggtcagccgc tgattcgcaa cagcacggtt
     3061 acggtctgca tattcaccgg gccagtaacc cgcgcctttt cggggcggga taagcgcgct
     3121 gattttctta cgccgcagtt catcgtgaca gagttgggtg tcgtaagcgc cgtctgccga
     3181 tgctgccctg atttttctgt gagtctgccg gataagaccc gggaaggctt ctgagtccgt
     3241 cacattgttc agcgacaggt ttgcacagat gatttcatgt gtgttgctgt caactgccag
     3301 atgcaacttt cgccatatac gacggcgttc ctggccatgc tttttgactt tccattcgcc
     3361 ttcaccaaag accttcagcc cggtggaatc aatcaccaga tgcgcgattt caccccgggt
     3421 gaacgttttg aaactgacat taaccgactt tgcgcgcttg ctgacactgg tgtaatccgg
     3481 gcagcgcaac ggaacattca tcagtgtaaa aatggaatca ataaaaccct gtgcagcccg
     3541 cagggtcaac ctgaacacgc gtttaatgac cagaacggtg gtgatggcga gatcagaata
     3601 gcgctgaggt cttccccgtg atgaaggcgt tgccgactca taccaggcct gaatagcttc
     3661 atcatccagc cagaaagtta tggagccacg gttgatgagg gctttattgt aggtgggcca
     3721 gttggttatt ttgaactttt gctttgccac ggaatggtct gcgttgtcgg gaagatgcgt
     3781 gatctgatcc ttcaactcag caaaagttcg atttattcaa caaagccgtc tgtgttgtaa
     3841 aatggcgccg aaagcccggc gtagccggtt gccgggctat aaattctgcc accctacccc
     3901 ctgccctgat tagccttaac tcgcgaacag caatgaagaa gtcaaagtaa tcccttttaa
     3961 ccccggtgag cgggctttac ggcgtttacg acgtaaaggg cgtgatttcc ggggcctaag
     4021 cggcggcagc ttgctgctga cgcttagggg gatgttcatc aactatttca gcgacaccag
     4081 ggaacttaac acggtagctg caaagcccta atcccgctca ccgccacgca gctgccgtac
     4141 gtcccccacg ggggtgcgca gtgctgcgcg cgggaacggc ggcccgtctg cgggacgcgg
     4201 cgccgtactg cgcgttagcg gccgcacgcg gccggttacg ggggacactc cgccatacga
     4261 ccagcgaccc gctgagctgc acaatccaca gataacacaa gctacataca tgtcgatatg
     4321 ggaatcggcc caccttgccg ggcgccggtg ccgtgtggaa atccgcccac cttgccgcgc
     4381 gccggtgccg tgtgggaatc cgcccacctt gccgcgcgcc ggtgccgtgt gggaatccgc
     4441 ccaccttgcc gggcgccggt gctgtgtgga aatccgccca ccttaccggg cgccggtgct
     4501 gtgtggaaat ccgcccatct tgccgggcgc cggtgccgtg tgggaatccg cccaccttac
     4561 cgggcgccgg tgctgtgtgg aaatccgccc atcttcatga caaaaatttg tcaaatgaca
     4621 ggctcatgtg tgctgattta tgtcagacgg gattttgctt atcaattatt gagaacagaa
     4681 attttcctga atcatcaata ctatacttag caagtaaagg tgttttctca tttatctgct
     4741 tgagtgcagg atcaaggaaa gatcgtttca actctgccaa gttcttctgc tgggattccg
     4801 gtaagacgaa acggtcattt aaccaagcat gagtagtaac ccataagcct gaagatttga
     4861 attgagcaag actttcataa aggcggatcg tccggggatt tcgaagactg ccacaatcgc
     4921 ggagcgagta ggtggtgaac tggttggtaa tgactccaac ttactgatag tgttttatgt
     4981 tcagataatg cccgatgact ttgtcatgca gctccaccga ttttgagaac gacagcgact
     5041 tccgtcccag ccgtgccagg tgctgcctca gattcaggtt atgccgctca attcgctgcg
     5101 tatatcgctt gctgattacg tgcagctttc ccttcaggcg ggattcatac agcggccagc
     5161 catccgtcat ccatatcacc acgtcaaagg gtgacagcag gctcataaga cgccccagcg
     5221 tcgccatagt gcgttcaccg aatacgtgcg caacaaccgt cttccggagc ctgtcatacg
     5281 cgtaaaacag ccagcgctgg cgcgatttag ccccgacata gccccactgt tcgtccattt
     5341 ccgcgcagac gatgacgtca ctgcccggct gtatgcgcga ggttaccgac tgcggcctga
     5401 gttttttaag tgacgtaaaa tcgtgttgag gccaacgccc ataatgcggg ctgttgcccg
     5461 gcatccaacg ccattcatgg ccatatcaat gattttctgg tgcgtaccgg gttgagaagc
     5521 ggtgtaagtg aactgcagtt gccatgtttt acggcagtga gagcagagat agcgctgatg
     5581 tccggcggtg cttttgccgt tacgcaccac cccgtcagta gctgaacagg agggacagct
     5641 gatagaaaca gaagccactg gagcacctca aaaacaccat catacactaa atcagtaagt
     5701 tggcagcatc accaatcatt tgatgattaa tcttagcgca aatctgcgat ctgatagact
     5761 tcgctgcttt cccttcttcc aacggcaata acgagtaaaa cgactttctc atcaatgact
     5821 tggtatacaa gtctgtagcc agatgcacga agtttgattt tatagcgatc agcatgacca
     5881 tgtaaccggg ctgcgggtac gcgtggattt tccagccgtt ctgccagttt ctttttgaat
     5941 tgttcacgga tggtgtggcc gagtttctgc cattccttca gtgctctacg gtcaaaagcc
     6001 agttcatagg tcatccaggt taaccttcac aatttccggg tttttcatgc gctcatcagc
     6061 aacagcgttt aactcagcat cttcagcgag ttcccgatag taggcgtaaa gttttggtgg
     6121 aacgcaatag aacgccggtt cgtttcggtt caggatcgca acagcgtccc cttcaccttc
     6181 agctacggtt cccataggat tttttttcag gtcagtaata ctggccgctg tagttgtcag
     6241 aatttgatag ctcataagcc ctccgcttgt ctcattggca taatagcatc tttaaaagca
     6301 ctcttaaaag tgcttatgtt gagaaaaaca tcagaacagg tgagatatgg ctctttccga
     6361 catcgcctta aaacgctctg taacgcgttc tgagcgtttt ttcccgtttc gttgtagtca
     6421 gctacggttt aacggttttt aacgccgctc aacgcttttt agcggccttg ttgctgtgat
     6481 ctgttgccat gatccggata ggagttcaat cttgatcaaa atttcctcaa ggcaacgact
     6541 gttttgtaaa taccctctaa aacgcgctgt atcgcattct gagcgatttt ttcgatttcg
     6601 catggtttca ccatggttgt atcgaacgaa gcggcagaaa gcgattcagg gcttctcagt
     6661 gaaagatcca aaaaggatca atcaacggat cgtatgagct gaactcttct ggttttgaga
     6721 aaggagacac cgctcgccgc agccgaacga ccgagtgtag cgagttagtg agcgaggaag
     6781 cggaatagca cagggattac attaggcact tacgcacagt ggttaaaaaa tgagcatatt
     6841 gtttttatgt gtggttgtct tggttcagag tgatctgtcc tccgggttta cgcaaagtta
     6901 tccacaggcg ctgtgaattt tttgttttga gcagagttat ccacagattt tttgtgtttt
     6961 tttgcttatt aaacttcttg tttttaagat cttaaatgta gatcggtaga tctactttaa
     7021 gatctttaac ttactttaac ttattctgca aacattgtgc cagctttttt atcaataatt
     7081 tcattaagat aggtgttgtt ttttgtcgcc tcaaaatgaa aggtggatgg gtacgcactg
     7141 aaaggtggat gggtacgcac tgtaattttc atgaaaggtg gatggctgcg cactgaaagg
     7201 tggatgggta cgcactgaaa ggtggatggg tacgcatttt tctgttttta ttcagatatt
     7261 cgtatctttg tatcttcatt tctttagttc tttatagtgc tctaatttaa cgtatgacgt
     7321 taaaaggtgg atacctgcgc atttctatca tattgaatat aaatgataaa aattctttca
     7381 tgtgatccgt gttttggtgg aaatacataa ggtggataaa ccactttaca tatttccgcc
     7441 tttgtggtta tgatttcacc atcagaactt aaaaaccaca ggtaatgtat gaacttactg
     7501 agcgttacaa agaaaacaaa aattcgccac agaaatgaaa ttaacagcac attctcatcg
     7561 ttgcctttgt ctgccagaag aattttgttt atggctatgg cgcagattga ttcacgtgaa
     7621 gagttatctg agggggcaac ctttcgtatt acggctcggg aatatgcatt tatcgctgat
     7681 attgatgtaa caggtgctta ccggcagttg aaagaggggg cagaagaact tcaggccagt
     7741 gttattcgca ttcctcgaaa tcaacttctc acacctcagg gcaatcaaag ctctggacat
     7801 acgaagaaga gaggtaaatt accttctgat gcagtcaggc ttatgaacct gactgcgttt
     7861 tgtgattatg ttgaaagtga aggatatatt gatattgctt tttcacatgt cattgagcca
     7921 tatatcacga tgttaaagga ttcttacact actcaggttt tgatatcgtc tgtaagactc
     7981 gctgatcaaa attcaaatat gctttatcag tttatcagga aacaatacag cagtggtaaa
     8041 aagacatttt tcgacattga agtagatgta ttaaaggatg aacttgaatt attcagaata
     8101 gataatggcg aaaaagttta cctttatcag aattttaagg attttaataa ggtttttctg
     8161 caaaaaaata ttgaaaaaat aaatcaatat acagagatta atcatctcga agttaaaatc
     8221 gttgagagag tcgcaagaag agcatcaaag ctaaggtttt cttataaaat agataaagaa
     8281 agtgagggct tagatatcag aataccatac ggtttcagag gataattgca taaacttcgt
     8341 tttgagatcg aaatgaggta gctcatggct aaaatctatc aattccctca gggggaagaa
     8401 cgtgctaaat tcaggaaaga aattgccagg gagcgtaaga aacgttttgc agtgaaaaca
     8461 gggagcactt ttgttaagtg gcttggctga ggatggtttt atcttcgtct tcttgtcgcg
     8521 agtgttttac attttatctt tgtttttgtg ttagccattc ttggtgcgtt taaatgggct
     8581 gtattctggc tgggtggtat tttgtgtgtc atcacttggt atcatctcga tcaccagtta
     8641 tggacgccac aaaatctgac tataccggtg attacggcaa cctggatttt gggactgctg
     8701 gctgagcctc tgatggagct gctcaacaaa actatgcctt ggcacaagtt acttgttccc
     8761 gaacctgcgg acgaaagcac cgagaacagt agcgagataa gccagcaatg atgctactca
     8821 gcagttatgc cagtccctgc cttttcactg cgatgcagga tagggcaaac gccgcaaaat
     8881 gacgtctctg acgccattct gcaacgtttg cccggtgacc tacagtcggt tcttgtcgga
     8941 gaattttatg gaatatcagg tgagagagtt tattaacgaa aaatatacta aggctgttaa
     9001 tattttaaag gataacctta aagaaaacta ccatgttttt tatggtgtga gattaattga
     9061 gattcttttt ccagccagtg agtatggcac tgatgctttc tttaaagagt ttgaattaat
     9121 taacagtgta atacttccat tggtaatctt tgatttaaca caacgcaagc caatgatgat
     9181 tatcagcttc gataagatac ttgatgccag tttgttggaa ggaacaaata ttgtggttct
     9241 tgaatgtatt accctcgctg atcttctgac aaatgataac attgattttt tatataaaag
     9301 ctaagaatct cctttcagtt taaattttct gcttgggtcg ccaagtgtta ttgagtctac
     9361 ttcatgtgag taatgaagtg tatgataatg tgctggattt ttcagataat cagggagtga
     9421 tattattttt ccgcagctaa ttgcagaatg aaaccagttg cggaatgtct cgctatttgt
     9481 ttttaatgca tcttttggaa taaatactaa ttttatgttg gaaacgtaat taacaggttt
     9541 aagtatggta tgtctgtttt gtccaaagtc ttttaaagca tctgtaaact cgtattcaga
     9601 tgtataaatt ctagtttctt tattaagggt tttgatctgg aatatgaatg aatagtaatt
     9661 cttatcaagt atttcaacag tgcctgggtc tatactcagt tgtttaataa cagcttctct
     9721 tttatactct aacccgtctc tgactgattg atatacaacc attgctgcat gatgtgagcc
     9781 accactgttt gaagctacat atcggtcaaa ccaagaataa tatttaacat taataggggg
     9841 gcgtgggggg aaaccttcat gctcaatgtg ccatatatta tctttccagt ctaaaatatt
     9901 ttcagctttc agattttcgg caggatacat cccctctccc caagaataaa gatctttgaa
     9961 ccaactacca tttattacct tgctccatcc acaaccgaaa cttttcgagt cagtcagaga
    10021 ttgtattttg ttaaaatcga agtccagaga gtgtttctta tctgtagtta ttaagttgct
    10081 cagaatttca gccagatcct tgtcaatata tctcagtgag tattcgctaa atatattttc
    10141 aagctgcaat atggtgtctg catctgctgt aggtttaaat aacttaatat cagcaagatt
    10201 tttaaacgtt gctgtggtca gtttatggtg atctgtcaac ctgtagaggt cacagatcaa
    10261 ttcggttaaa tatctcatag attttcatcc atgcttctat ggttagaatt ttgcagactc
    10321 aagcaaccag tgattcttta tgttttcatc ctggctgttg tacatcgcca gcgccgcttt
    10381 gagaacggtt gttttgctct gccctgttct gatagcttca gcttccagta tgtcctcaaa
    10441 atgggctgaa agtctgaagt tcatcaactt tggtttaccc actacaggcg ctctggtagc
    10501 gccggagata aaacgcgcgg tttctgcgtt tgttgctggt tgctgagatt catcgatgtt
    10561 cggacggttt agttttaaag ccatgacaat ttccccttgt acggtatgca ttaatagtaa
    10621 atatcatact atctttatat tatctttaca atgtaaagat ttatagatgg tattgatatt
    10681 actataaaat tccaatttcc tgcgccacta gttcaatctg tgctttcgct gttgaaaggc
    10741 ttgatgcccg gctaacgtca tgtacccctg ccccttcatt acaggcgctt tcatacacat
    10801 ccagctcgga tatccgggtt ttaagaggtt gaatccagat gttgtccgaa cgcagtaatt
    10861 tatccagatc aatggccgct tttctgtggc ggggtttcgc tgagttgatt ctggtgaaca
    10921 gcacccacgg ttccagggct gcgttagctt tctgagcggt gcggattttc tctgtaacac
    10981 tggtcagagt ttcgctttcg aaatcagagg acggcttaac cagtgttacc acgatatctg
    11041 atactgtcag ggcgctacgg aactcctggc tgtcgtggcc ggggcaatcg acaatgagga
    11101 cttcacacag cttactaagt cgcttaattt cattgctgac gtttccgtaa gctgcgtgaa
    11161 ccgggatagt gagtaagccg ttatctgtcc gcttttcgtt ccagctcaac agatcgtggt
    11221 ttttatctgt cttgaggata attaccgact tacctttatt gaccagcatt gagcctgtgt
    11281 tagccacgta ggtgcttttg cctacaccac ccttatctga tacgacaagc aagattttac
    11341 ccatttcaga attcctctct ttatgacgta aagattatgt aaagactgtc ttatctttac
    11401 attgtgtgtt gttcgtaaag attattttgt ctttacagtg tctttatatt acacatgatt
    11461 taccatgtaa agcacaaata aagataagct tgtatttatg ttatctttat tgtgtaaaga
    11521 tttgtgtgta tttatagtgg ctttacgtgg taaatctgag accgtcttta catcatcttt
    11581 atgttgtaaa tttctgtgtg acattgtcac tttatggtcg gaggtctgtt ttctggttct
    11641 ttttgagtat gccttttaaa taccacccat aacgggtact gtatagttat gctttaacta
    11701 cctaaatcga actggttcta cactgtgact caaactgtac cgaaaggctt tgtccgggct
    11761 tatttacgcg cctctacatc tgaacaagat gcttctcgcg ctctggctgc gattgatagt
    11821 tttgccgagg aacgtgggct gaacatttgc aattactaca ttgagaatga atctggttcg
    11881 aggcttgacc ggcctgaatt attcaggttg ctcaaagact gccggcacaa cgatattctc
    11941 ttaattgagg atgtagatcg gctctcacgt ctgactggcg aagactggaa cagcttgaaa
    12001 aaattgatta ggcagaaaga tatacgagtg atggccatca acgttccgac aacatggata
    12061 gcttcaggaa gccatgattt tgatagccgc atgtttgctg caattaacga tatgttgctc
    12121 gacatgctgg ctgctgtggc acgtcgtgac tatgaacaac gccgggaacg tcaaagacag
    12181 gggattagta aagctcaaaa agagggaagg tataaggggc gacaggccaa taaggagcga
    12241 tacgatgcca tcaatcggtt gctcgatagc ggtagttcct ggagtcaggt acagaaaatt
    12301 atggcctgta gtcgagggac aattagtagt gctgtaaaat cgaggaagtt gaacgccatt
    12361 taagctagta gttacaacac tcaatagaat ttaagccgac tctgcttggc ttgcgagtgt
    12421 ggctaatagg ggagcccgca gaattcggaa aaaatcgtac gctaaggttt tccgggcatc
    12481 cgtaagggcc gaaacttccc gtcttccagt ctgcggctct gccgccagac gtaatcgccg
    12541 gttaggttga tgtgctccca gcccagcggc gacaggaatt gcagcagctc gccgtccacc
    12601 ggcttgccgg cctcgaccaa cccctgggtg gcgcgttcca ggtacaccgt gttccacagc
    12661 acgatagccg ccgtcaccag gttgaggccg ctggcccggt agcgctgctg ctcgaagctc
    12721 cgatccctga tttccccaag gcggttgaag aacaccgccc tggccagcga gttgcgcgcc
    12781 tcacctttgt tcaggccggc atgcacgcgg cggcgcagtt caacactttg cagccagtcc
    12841 aggatgaaca gcgtgcgctc gatccggccc agctcgcgca gggccacggc cagtccgttc
    12901 tggcgcgggt agctgccgag cttgcgcagc atcagcgagg cggtgacggt gccctgcttg
    12961 atcgagctgg ccaggcgcag gatgtcgtcc cagtgggcac gcacgtgctt gatgttcagg
    13021 gtgccgccga tcagcgggcg caacgtcggg taggcttgca cgccctgcgg cacgtacagc
    13081 ttggtttcgc cgaggtcgcg gatgcgcggc gcgaagcgga agcctagcag gtgcatcagg
    13141 gcaaagacgt gatcggtgaa gccggccgtg tcggtgtagt gctcctcgat ccgcaggtcg
    13201 gactcgtggt acagcaggcc gtcgagcaca taggtggaat cgcggacgcc gacattcacc
    13261 acgcgggtgc tgaacggggc actgttgcaa atagtcggtg gtgataaact tatcatcccc
    13321 ttttgctgat ggagctgcac atgaacccat tcaaaggccg gcattttcag cgtgacatca
    13381 ttctgtgggc cgtacgctgg tactgcaaat acggcatcag ttaccgtgag ctgcaggaga
    13441 tgctggctga acgcggagtg aatgtcgatc actccacgat ttaccgctgg gttcagcgtt
    13501 atgcgcctga aatggaaaaa cggctgcgct ggtactggcg taacccttcc gatctttgcc
    13561 cgtggcacat ggatgaaacc tacgtgaagg tcaatggccg ctgggcgtat ctgtaccggg
    13621 ccgtcgacag ccggggccgc actgtcgatt tttatctctc ctcccgtcgt aacagcaaag
    13681 ctgcataccg gtttctgggt aaaatcctca acaacgtgaa gaagtggcag atcccgcgat
    13741 tcatcaacac ggataaagcg cccgcctatg gtcgcgcgct tgctctgctc aaacgcgaag
    13801 gccggtgccc gtctgacgtt gaacaccgac agattaagta ccggaacaac gtgattgaat
    13861 gcgatcatgg caaactgaaa cggataatcg gcgccacgct gggatttaaa tccatgaaga
    13921 cggcttacgc caccatcaaa ggtattgagg tgatgcgtgc actacgcaaa ggccaggcct
    13981 cagcatttta ttatggtgat cccctgggcg aaatgcgcct ggtaagcaga gtttttgaaa
    14041 tgtaaggcct ttgaataaga caaaaggctg cctcatcgct aactttgcaa cagtgccatg
    14101 ttcctgttat ggcttatgtt caagaaagca ttgcccctga aatgatgggc aaggtgtttt
    14161 cccttttgat gaccgccatg actctttcta tgccgatagg cttacttgtt gcaggtccgg
    14221 ttgttgaggt tataggtgtt aatacatggt ttttctggtc tggtgttgcg ttgatagtaa
    14281 acgctgttct ctgccgcatt ctgacacgac gctatgacaa agtaacaatg aaaaccgcaa
    14341 gtggactgaa aaaaggaccg ggttgatgat aatttgtagt agtgagcttc tgggagtaca
    14401 aaacaaagtg ctcaaaattg tcgggctcat ggcgtttaac ggtattaatt tcgcttataa
    14461 taatctttct ataatagcct aaaggagaat atctatgata cctaatagcg aaaataaaag
    14521 agtatggttt attaccggag caagcaaggg gcttggctat gcttttacat gcgccgcctt
    14581 gaaagccggg gataaagttg ttgcagttgc aaggactatc gataatttgg cgaagctaga
    14641 agaaacatat caagagagct tactgccatt aaacctcgat gttacagata gggaggctgt
    14701 tttttctacg gttgaaacag cagttaaaca tttcggtagg cttgatattg ttgttaataa
    14761 tgcgggtatc atgactatgg gtatgattga agaactaaac gaatccgatg ctcggaaact
    14821 aatggacaca aacttttttg gagctctttg ggtttgtcag gcagtgatgc cctatttgag
    14881 gtcgcagcgt tctggacata tcatacagat tacaagcatt ggcgctatta tctcgggtcc
    14941 gatgtctggt atttacagtg caagtaaatt tgcgctggaa ggaatgagtg aagccttagc
    15001 aaaagaagcg gaacatttcg gagtgaaact cactatggtg gaaccaggag gatattggac
    15061 agatttatac acttcgatga gttacagcaa tccattagat tcatacggta cactgcgcga
    15121 tgagctggcg aaacagtatt ccgaagattc ggtcgatagt gatccttcct tggcagcgga
    15181 agcccttatg aaattagtag ccagcaataa tccgcctttg aggcttatcc ttggcagcat
    15241 ggtatacgat ttggcgatgg ataccttaaa agcacggatg gctacctggg aagaatggga
    15301 agctgttagc cgtgcatcag aaaaggctat tcctgcaccg gagagatatg gagtataata
    15361 ccaaacatgg tttttgaggc aaggacgaaa ctatcatgaa aattgaaatt atggaatata
    15421 acccggattg gacaaagaat tttgaagaag agaaaataaa attgctccat tttttcggtt
    15481 ctcatgccgt agccattgaa catatcggaa gcacggcgat acccaatcaa cgggcgaaac
    15541 cggttataga tatatttatt ggcgtttcgc cttttgctga actacctttt atcagcgcat
    15601 ttttaatgca aaggagtatc accacactcc gacagatatg acaggcagat atttgtttgc
    15661 aaaatataca aatgaagttt ggacccataa tcttcttgct ttggtgtagg tataataccc
    15721 aaaaacgaag tttatgcgga acaggataac acctcgaaat cggagtttat atggcttcgt
    15781 gggggagtta tgtgtttgag ctttgtcgca ttaacgcgaa tcaggggttg acggcagaaa
    15841 tagactggaa ttacacttct tggagtcggc gttgccggaa aattctgatt ggattagttg
    15901 ttcggggtgc gaaaacagtc gtagttcggg gaaaaaaccg aattttgacc caaaaccgcg
    15961 aaaaactcga aatgacagtt cctatcagtt ttcataatga attaaaacaa aaaaattagg
    16021 ctgcaaagat agggaaaatg tgtcaatttg cgtaagtgat aattagtcaa ttaagataaa
    16081 tgctactttt gtaatcaaag caaaatgata tgagcaagat ttttggaatc gtaaatataa
    16141 ccaccgatag tttttccgat ggaggacttt atttagatac agataaggca attgagcatg
    16201 ctctgcattt ggttgaagat ggagcagatg tgattgattt gggagccgct tccagtaatc
    16261 ctgatacaac tgaagtgggc gttgtggaag aaatcaaaag actcaaacct gtcattaagg
    16321 ctttaaaaga aaaaggcatt tctatttctg ttgatacatt taaacctgag gttcagagtt
    16381 tttgcataga acaaaaggtt gattttatta atgatattca aggttttcct tatcctgaga
    16441 tttattcagg cttggcaaag tcagattgca aacttgtgtt gatgcactcc gttcagcgaa
    16501 ttggtgcagc tactaaagtt gaaacgaatc cggaagaggt ttttacttcc atgatggaat
    16561 tttttaaaga aagaattgct gctttagttg aggctggtgt aaagcgtgaa cgaattattc
    16621 ttgatccggg tatgggcttc tttttaggct ctaatccaga aacatctatt cttgttttga
    16681 agcgtttccc tgaaattcaa gaagctttta atttgcaagt aatgattgca gtgtcacgga
    16741 aatcattctt aggtaaaata actggaaccg atgtgaaatc tcgtttagca ccaactcttg
    16801 cagcagaaat gtatgcatac aaaaaaggtg cagattatct ccgcacccat gatgttaagt
    16861 ctttatcaga tgccttgaaa atatccaaag ccctaggtta gttttatttt tttagctttc
    16921 taaatgaata tgctatactt gctctgaagt tgtgttggcg tacttgactt aggtctggat
    16981 ctttcgaact gttactaaga gggtaatcat aggggtctga cgctcagtgg aacgaaaact
    17041 cacgttaagg gattttggtc atgagattat caaaaaggat cttcacctag atccttttaa
    17101 attaaaaatg aagttttaaa tcaatctaaa gtatatatga gtaaacttgg tctgacagtt
    17161 accaatgctt aatcagtgag gcacctatct cagcgatctg tctatttcgt tcatccatag
    17221 ttgcctgact ccccgtcgtg tagataacta cgatacggga gggcttacca tctggcccca
    17281 gtgctgcaat gataccgcga gacccacgct caccggctcc agatttatca gcaataaacc
    17341 agccagccgg aagggccgag cgcagaagtg gtcctgcaac tttatccgcc tccatccagt
    17401 ctattaattg ttgccgggaa gctagagtaa gtagttcgcc agttaatagt ttgcgcaacg
    17461 ttgttgccat tgctgcaggc atcgtggtgt cacgctcgtc gtttggtatg gcttcattca
    17521 gctccggttc ccaacgatca aggcgagtta catgatcccc catgttgtgc aaaaaagcgg
    17581 ttagctcctt cggtcctccg atcgttgtca gaagtaagtt ggcagcagtg ttatcactca
    17641 tggttatggc agcactgcat aattctctta ctgtcatgcc atccgtaaga tgcttttctg
    17701 tgactggtga gtactcaacc aagtcattct gagaatagtg tatgcggcga ccgagttgct
    17761 cttgcccggc gtcaacacgg gataataccg caccacatag cagaacttta aaagtgctca
    17821 tcattggaaa acgttcttcg gggcgaaaac tctcaaggat cttaccgctg ttgagatcca
    17881 gttcgatgta acccactcgt gcacccaact gatcttcagc atcttttact ttcaccagcg
    17941 tttctgggtg agcaaaaaca ggaaggcaaa atgccgcaaa aaagggaata agggcgacac
    18001 gaaaatgttg aatactcata ctcttccttt ttcaatatta ttgaagcatt taccagggtt
    18061 attgtctcat gagcggatac atatttgaat gtatttagaa aaataaacaa ataggggttc
    18121 cgcgcacatt tccccgaaaa gtgccacctg acgtctaaga aaccattatt atcatgacat
    18181 taacctataa aaataggcgt atcacgaggc cctttcgtct tcaagaattt tataaaccgt
    18241 ggagcgggca atactgagct gatgagcaat ttccgttgca ccagtgccct tctgatgaag
    18301 cgtcagcacg acgttcctgt ccacggtacg cctgcggcca aatttgattc ctttcagctt
    18361 tgcttcctgt cggccctcat tcgtgcgttc taggatcctc cggcgttcag cctgtgccac
    18421 agccgacagg atggtgacca ccatttgccc catatcaccg tcggtactga tcccgtcatc
    18481 aatgaaccgg actgccacgc cctgagcgtc aaattccttt atcagttgga tcatatcggc
    18541 agtgtcgcgg ccaagacggt cgagcttctt aaccagaatg acatcacctt cctccacctt
    18601 catcctcagc aaatccagcc cttcccggtc tgttgaactg ccggatgcct tatcggtaaa
    18661 tatacggttt gctttcacac ctgcgtcttt gagtgctctg acctgaagat caagagactg
    18721 ctgactggtt gagacccgag cgtaaccaaa aagtcgcata aaaatgtacc ttaaatcgaa
    18781 tatcggacaa ctcatgtcta ttattacaaa tttacgattt aatagacata ttaatgtaac
    18841 agttttacga tgtccgataa tttataacat ttcgtacggt tggaaaaatg ttactaaatg
    18901 cccgtcaggc agggaggccg atatgcccgt tgactttctg accactgagc agactgaaag
    18961 ctatggcaga ttcaccggtg aaccggatga gcttcagctg gcacgatatt ttcaccttga
    19021 tgaagcagac aaggaattta tcggaaaaag cagaggtgat cacaaccgtc tgggcattgc
    19081 cctgcaaatt ggatgtgtcc gttttctggg caccttcctc accgatatga atcatattcc
    19141 ttccggcgtc cggcatttta ccgccagaca gctcgggatt cgtgatatca ccgttcttgc
    19201 agaatacggt cagagggaaa atacccgccg tgagcatgca gcgctgatac gtcagcacta
    19261 tcagtatcgt gaatttgcct ggccctggac atttcgcctt acccgtcttt tatatacccg
    19321 gagctggata agcaacgaac gtcctggcct gcttttcgat ctggcgacag ggtggcttat
    19381 gcaacatcgt attattctcc ccggagccac tacgctgacc cggttgattt cagaggtaag
    19441 ggaaaaggcg acgttgcgcc tgtggaacaa actggcactg ataccgtcag ccgaacagcg
    19501 ttcacagctg gagatgctgc tggggccaac tgattgcagc cgcctgtctt tactggaatc
    19561 actgaaaaag ggccctgtga ccatcagtgg tccggcgttt aatgaagcaa ttgaacgctg
    19621 gaaaactctg aacgattttg gcctgcatgc tgaaaacctg agtacactcc cggctgtgcg
    19681 cctgaaaaat ctcgcacgtt atgctggtat gacttcggtg ttcaatattg ccaggatgtc
    19741 accgcagaaa aggatggcgg ttctggttgc ctttgtcctt gcatgggaaa cgctggcgct
    19801 ggatgatgca ttggacgttc tggacgccat gctggccgtt atcatccgtg acgccagaaa
    19861 gattgggcag aaaaaacggc tccgctcgct gaaggatctg gataaatctg cattggcgct
    19921 cgccagcgca tgttcgtacc tgctgaaaga agaaacaccg gacgaatcga ttcgtgctga
    19981 ggtgttcagc tacatcccaa ggcaaaagct ggctgaaatc atcacgcttg tccgtgaaat
    20041 tgcccggccc tcagacgata attttcatga agaaatggtg gagcagtacg ggcgcgttcg
    20101 tcgtttcctg ccccatctgc tgaataccgt taaattttca tccgcacctg ccggggttac
    20161 cactctgaat gcctgtgact acctcagccg ggagttcagc tcacggcggc agttttttga
    20221 cgacgcacca acggaaatta tcagtcggtc atggaaacgg ctggtgatta acaaggaaaa
    20281 acatatcacc cgcaggggat acacgctctg ctttctcagt aaactgcagg atagtctgag
    20341 gcggagggat gtctacgtta ccggcagtaa ccggtgggga gatcctcgtg caagattact
    20401 acagggtgct gactggcagg caaaccggat taaggtttat cgttctttgg ggcacccgac
    20461 agacccgcag gaagcaataa aatctctggg tcatcagctt gatagtcgtt acagacaggt
    20521 tgctgcacgt ctttgcgaaa atgaggctgt cgaactcgat gtttctggcc cgaagccccg
    20581 gttgacaatt tctcccctcg ccagtcttga tgagccggac agtctgaaac gactgagcaa
    20641 aatgatcagt gatctactcc ctccggtgga tttaacggag ttgctgctcg aaattaacgc
    20701 ccataccgga tttgctgatg agtttttcca tgctagtgaa gccagtgcca gagttgatga
    20761 tctgcccgtc agcatcagcg ccgtgctgat ggctgaagcc tgcaatatcg gtctggaacc
    20821 actgatcaga tcaaatgttc ctgcactgac ccgacaccgg ctgaactgga caaaagcgaa
    20881 ctatctgcgg gctgaaacta tcaccagcgc taatgccaga ctggttgatt ttcaggcaac
    20941 gctgccactg gcacagatat ggggtggagg agaagtggca tctgcagatg gaatgcgctt
    21001 tgttacgcca gtcagaacaa tcaatgccgg accgaaccgc aaatactttg gtaataacag
    21061 agggatcacc tggtacaact ttgtgtccga tcagtattcc ggctttcatg gcatcgttat
    21121 accggggacg ctgagggact ctatctttgt gctggaaggt cttctggaac aggagaccgg
    21181 gctgaatcca accgaaatta tgaccgatac agcaggtgcc agcgaacttg tctttggcct
    21241 tttctggctg ctgggatacc agttttctcc acgcctggct gatgccggtg cttcggtttt
    21301 ctggcgaatg gaccatgatg ccgactatgg cgtgctgaat gatattgcca gagggcaatc
    21361 agatccccga aaaatagtcc ttcagtggga cgaaatgatc cggaccgctg gctccctgaa
    21421 gctgggcaaa gtacaggttt cagtgctggt ccgttcattg ctgaaaagtg aacgtccttc
    21481 cggactgact caggcaatca ttgaagtggg gcgcatcaac aaaacgctgt atctgcttaa
    21541 ttatattgat gatgaagatt accgccggcg cattctgacc cagcttaatc ggggagaaag
    21601 tcgccatgcc gttgccagag ccatctgtca cggtcaaaaa ggtgagataa gaaaacgata
    21661 taccgacggt caggaagatc aactgggcac actggggctg gtcactaacg ccgtcgtgtt
    21721 atggaacact atttatatgc aggcagccct ggatcatctc cgggcgcagg gtgaaacact
    21781 gaatgatgaa gatatcgcac gcctctcccc gctttgccac ggacatatca atatgctcgg
    21841 ccattattcc ttcacgctgg cagaactggt gaccaaagga catctgagac cattaaaaga
    21901 ggcgtcagag gcagaaaacg ttgcttaacg tgagttttcg ttccactgag cgtcagaccc
    21961 ctaaaatcct gatgctgatg tagtcccgtt ttatcgtcat cacgaagctt tctgctatgc
    22021 cattgctttc cgggcttcgc actgctgtcg tacaaggctc cagtcccagc aaccgggcga
    22081 acgccggcac tgttggcaac tgccttccga agcgtttttc caccgcaccc agcatgacat
    22141 cctgcaccgt ttctttgtca tagcctccgg tgctcgctgc ccagtcaatg atctccctgt
    22201 cgcagcagtc ctgcgcgaag gtcacccgca gcttttcgcc attatcacag cggaactcaa
    22261 agccatctga gcaccagcgc cggttacttt ccgctactgc tacgcgcccc ttatgggccc
    22321 gcttacggca aggatcagcg ggtttacgtt caagaagcag attatgcgtt ctcataatgc
    22381 gatacacccg ctttgcatta accacaggca ggccgtcccg ctccgactcc cgtcgcagca
    22441 gcgcccacac acggcgataa ccatacgtcg gcaggtcagc caccgccatg tttatccggg
    22501 acaatacggt ggtatcgtca gaacggggct gccgtctgcg atcctgtcag tcagatggcc
    22561 ggtgaacccg aatgctcaac tgcgcacgcg acacgccaag acttctgcaa acgtcgctta
    22621 ttcgtcgttc ccaggcaacg agggcgcatg cgcaatccat ttttttgccc ggccgaactc
    22681 cacggcctct ttgagtatct cggcttccat cgtctttttg cccagaaggc gctggagttc
    22741 gcgaatttgc ttattggcgg cagcgagttc ggaggccggc accacttcct cgcccgatgc
    22801 aacagccgtc agtgaaccgt cttaatattg cttgcgccat ttgaatatct ggtttgcatt
    22861 gatgccatgc aggcgcgcga catgagacac ggtcataccg ggctccatag tctgctgaat
    22921 aatggcaatt ttttcctgcg gtgtacgacg ccgacgccgc tcaggtcctg ataacacttc
    22981 aaccatctta tcgttctgac tggtattaaa catagttcca agactacctc ttattttaag
    23041 agagtcgaag tgtctggtga tctatggggc cagtctagcc ctcttccaag tgtagggaga
    23101 tatagtcaaa gtttgcttct ccgccgatga gtccgccctg cgtcggatag tccgattttt
    23161 taccggcgaa gcacggctct cctaacccta tctaaagcga ataacttttt tcaacagggc
    23221 cgcgtgccaa tgcaagagcg ataggcgctc tacgcgccaa tttgaccact taaaacaggt
    23281 aaattgaggg gttgtaatgt gttgatgtaa caggctttta ttttaatgtc ttggcatatg
    23341 tataatggta gtctagccct cctttcaaca aggagtactc atggaaacct acaatcatac
    23401 atatcggcac cacaactttt cacataaaga cttaagtgat ctcaccttca ccgcttgcac
    23461 attcattcgc agcgactttc gacgtgctaa cttgcgtgat acgacattcg tcaactgcaa
    23521 gttcattgaa cagggtgata tcgaaggctg ccactttgat gtcgcagatc ttcgtgatgc
    23581 aagtttccaa caatgccaac ttgcgatggc aaacttcagt aatgccaatt gctacggtat
    23641 agagttccgt gcgtgtgatt taaaaggtgc caacttttcc cgaacaaact ttgcccatca
    23701 agtgagtaat cgtatgtact tttgctcagc atttatttct ggatgtaatc tttcctatgc
    23761 caatatggag agggtttgtt tagaaaaatg tgagttgttt gaaaatcgct ggataggaac
    23821 gaacctagcg ggtgcatcac tgaaagagtc agacttaagt cgaggtgttt tttccgaaga
    23881 tgtctggggg caatttagcc tacagggtgc caatttatgc cacgccgaac tcgacggttt
    23941 agatccccgc aaagtcgata catcaggtat caaaattgca gcctggcagc aagaactgat
    24001 tctcgaagca ctgggtattg ttgtttatcc tgactaattg ctttgatgtg tgattttaaa
    24061 cgctcaaatt tataaaacga ataatattgt caaccttgca ataatagaca tagggacaac
    24121 catgtataaa tttttaccct caggcgtctt cacaatagag ccatatagca gtgggtcact
    24181 tagtgggctt aatttttcca ttaaagataa tattaatatt gctcagtata aaacatcata
    24241 tggtagccca tcttggcaag taaacataag gctgccattt ataaggcact gttgcaaaaa
    24301 tgtggaggtg ataggggtac tacgccggaa ccccagattt ttccgtccgt tcaaattatc
    24361 cacggttgag cagcttgatc ccgtccgccc gcagttgacc aacaggggaa atatgcctgt
    24421 acaaagtttg ccgggttatc ccaagttcct ggcatagcgt actgaccttt gtttctgatt
    24481 gtcccattga tgccattgcc agtcgcagtt tgactggcgt cattttataa ggtcggccgc
    24541 cgttccgccc acgggctctt gctgatgcca gacctgcagt cgttctttca gcaatcagtt
    24601 cgcgctcaaa ctccgccagt gcggcaaaga taccgaagac aagcttgcca gcggccgttg
    24661 ttgtgtcgat agtcgccccg tgaccggtca gcactttcag accggtcccc ctcgcggtca
    24721 ggtcgtgcac tgtattaatg agatgacgaa gatcacgacc gaggcggtcc agcttccata
    24781 cgaccgagag cataaaaaat attggggcag cgtgagctat gctgccatcg ctggtccctt
    24841 cccgtcactt tgaaaacccg gataccagca gacaaattta tcctgcagtt cgttattcaa
    24901 aacggcggtc cgggtctgta acaaataatg agcccctttt ctgctccact gcatctgctg
    24961 ctttttggcc attcgtctgg cgatcacttc attgatcgtg gattccacaa acgcggttga
    25021 taccggctct ccgtaccgac gcatttcgcc gtagtttggg atcatcatct tattattccg
    25081 gatgtaggta tacatttcat ccagatgttt ttgcagggat ttcaggctag gatagctgag
    25141 ttcagggtca tcgcaataca taacgcaatt atcaatatgt tccagcgcag cgacaacatt
    25201 gccatgccag agatatcgtt taatgctttc cagcagtgcc agaactttac tccccgcctc
    25261 tggatctgat accagcagtc cccgggcata ttgcatgagc accttcagcc tcatggtgat
    25321 atgaaaccag tccagcacat gcgttgactc agggtacata ccgaactgga ggtccctgag
    25381 attatccgcg ccgtcggaca gaaaaaatat ctgctggttg gcctgcattc cctgcgctga
    25441 aaggtgggtc atgagcctgc gttccggatg acagtcatcc ttctgaacaa aaccgaagcg
    25501 gcgggtgtca gcaggcgcac caacggaaaa agacttcccg gcaataattt caaaattacg
    25561 ctttttgtca tcccgatcgc gaacataacc accatctata cccaccacaa gcggttttcc
    25621 tggcctgggc aggttccccc agtcgcgggg gcagccggaa agaaaacctg aatgagcttc
    25681 agcctcagcg tcaagacgct gcgccacctg gcataaatga ttcctcaccg ttgaggcatt
    25741 caggctgtgg cccaccggca gaatatcttt cagcagacga gtcgtcattt cataggagat
    25801 catcgaggcc cagcgggttt caatatattt cagtgccggg tgagaataat cgccggccca
    25861 gtcgctgagc aaactgactg tctttgtatc actctcttca caacggcacc ggtacacccg
    25921 aagcccggat accggaataa cgccaaacag cgtccggtac cgtattttct gtttgccttt
    25981 gattctgcgc gcagcaaggc agtgagggca ccggatatgg tgttgagtat attcgtctgc
    26041 ctgcagctgg accaccgact gctggaccgt attcagcaac agcttggatt ctgacaccga
    26101 taatccgatg tcgttccggg tctcccctga tttctggatt gtcatcagtt cctccgttcg
    26161 actggagcct gattcatcgg tgatgactat ctggagcggg cactgttgca aatagtcggt
    26221 ggtgataaac ttatcatccc cttttgctga tggagctgca catgaaccca ttcaaaggcc
    26281 ggcattttca gcgtgacatc attctgtggg ccgtacgctg gtactgcaaa tacggcatca
    26341 gttaccgtga gctgcaggag atgctggctg aacgcggagt gaatgtcgat cactccacga
    26401 tttaccgctg ggttcagcgt tatgcgcctg aaatggaaaa acggctgcgc tggtactggc
    26461 gtaacccttc cgatctttgc ccgtggcaca tggatgaaac ctacgtgaag gtcaatggcc
    26521 gctgggcgta tctgtaccgg gccgtcgaca gccggggccg cactgtcgat ttttatctct
    26581 cctcccgtcg taacagcaaa gctgcatacc ggtttctggg taaaatcctc aacaacgtga
    26641 agaagtggca gatcccgcga ttcatcaaca cggataaagc gcccgcctat ggtcgcgcgc
    26701 ttgctctgct caaacgcgaa ggccggtgcc cgtctgacgt tgaacaccga cagattaagt
    26761 accggaacaa cgtgattgaa tgcgatcatg gcaaactgaa acggataatc ggcgccacgc
    26821 tgggatttaa atccatgaag acggcttacg ccaccatcaa aggtattgag gtgatgcgtg
    26881 cactacgcaa aggccaggcc tcagcatttt attatggtga tcccctgggc gaaatgcgcc
    26941 tggtaagcag agtttttgaa atgtaaggcc tttgaataag acaaaaggct gcctcatcgc
    27001 taactttgca acagtgcc
//
