LOCUS       NZ_CP049849             6336 bp    DNA     circular CON 14-JUN-2024
DEFINITION  Escherichia coli strain UPEC-245U/190328 plasmid pEcoUTI1c, complete
            sequence.
ACCESSION   NZ_CP049849
VERSION     NZ_CP049849.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14277527
            Assembly: GCF_023376095.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6336)
  AUTHORS   Velez-Sanchez,D., Ochoa,S.A., Cruz-Cordova,A., Lopez-Martinez,B.,
            Parra-Ortega,I., Escobedo-Munoz,A.S., Bustos,P., Cevallos,M.A. and
            Xicohtencatl-Cortes,J.
  TITLE     Comparative Genomics of Uropathogenic Escherichia coli Strains
            Isolated from Adult Women with Recurrent Urinary Tract Infections
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6336)
  AUTHORS   Velez-Sanchez,D., Ochoa,S.A., Cruz-Cordova,A., Lopez-Martinez,B.,
            Parra-Ortega,I., Escobedo-Munoz,A.S., Bustos,P., Cevallos,M.A. and
            Xicohtencatl-Cortes,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAR-2020) Centro de Ciencias Genomicas, Universidad
            Nacional Autonoma de Mexico, Circuito Universidad, Cuernavaca 66210,
            Mexico
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-FEB-2020
            Assembly Method                   :: Unicycler v. v0.4.1
            Assembly Name                     :: UTI-2_GENOME
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 208.905x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023376095.1-RS_2024_06_14
            Annotation Date                   :: 06/14/2024 05:43:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,247
            CDSs (total)                      :: 5,122
            Genes (coding)                    :: 4,924
            CDSs (with protein)               :: 4,924
            Genes (RNA)                       :: 125
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 93
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 68 of 198
            Pseudo Genes (incomplete)         :: 124 of 198
            Pseudo Genes (internal stop)      :: 38 of 198
            Pseudo Genes (multiple problems)  :: 31 of 198
            Pseudo Genes (short protein)      :: 1 of 198
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP049849.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6336
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="UPEC-245U/190328"
                     /isolation_source="bladder epithelial biopsy from
                     30-year-old female patient with recurrent urinary tract
                     infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pEcoUTI1c"
                     /geo_loc_name="Mexico: Mexico City"
                     /collection_date="2019-03-28"
                     /collected_by="Hospital Militar de Especialidades de la
                     mujer y neonatologia"
     gene            join(6256..6336,1..78)
                     /locus_tag="G9W35_RS26310"
     CDS             join(6256..6336,1..78)
                     /locus_tag="G9W35_RS26310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071529495.1"
                     /translation="MHEPPVQPDRCALSGNYRLESNPVRHDKAPLAAATGNWTRWIEIL
                     RVLEVVA"
                     /name="replication initiation protein"
     gene            393..998
                     /locus_tag="G9W35_RS26020"
                     /old_locus_tag="G9W35_25905"
     CDS             393..998
                     /locus_tag="G9W35_RS26020"
                     /old_locus_tag="G9W35_25905"
                     /inference="COORDINATES: protein motif:HMM:NF024197.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="WP_249756343.1"
                     /translation="MHLEEEDLRALERAVELLEQDTITETLTQLVGTPIDYLMSKLPKG
                     AEKKIYSLVEKSLNKAANAALWSLDNEPNRIASTKTNKFFAALSGAIGGAFGFSALAIE
                     LPVSTTIMLRSIADIARSEGFDLDRIDTKLECLAVFSFGGPSEDDDAVNTAYYATRNLT
                     AEIVQDLSKEISNIAVKNAASTQTGKWLGSLICPGSFY"
                     /name="EcsC family protein"
     gene            977..1294
                     /gene="sugE"
                     /locus_tag="G9W35_RS26025"
                     /old_locus_tag="G9W35_25910"
     CDS             977..1294
                     /gene="sugE"
                     /locus_tag="G9W35_RS26025"
                     /old_locus_tag="G9W35_25910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="WP_000118520.1"
                     /translation="MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIAM
                     LSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKLST
                     H"
                     /name="sugE"
     gene            complement(1291..1824)
                     /locus_tag="G9W35_RS26030"
                     /old_locus_tag="G9W35_25915"
     CDS             complement(1291..1824)
                     /locus_tag="G9W35_RS26030"
                     /old_locus_tag="G9W35_25915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="WP_001221666.1"
                     /translation="MRILPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWYE
                     IARFDHRFERGLDKVTATYSLRDDGGINVINKGYNPDREMWQKTEGKAYFTGDPSRAAL
                     KVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEMKQQMLAIATREG
                     FEVNKLIWVKQPGA"
                     /name="lipocalin family protein"
     gene            complement(1918..>2820)
                     /gene="ampC"
                     /locus_tag="G9W35_RS26035"
                     /old_locus_tag="G9W35_25920"
                     /pseudo=""
     CDS             complement(1918..>2820)
                     /gene="ampC"
                     /locus_tag="G9W35_RS26035"
                     /old_locus_tag="G9W35_25920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="class C beta-lactamase"
                     /name="ampC"
     gene            2889..3869
                     /locus_tag="G9W35_RS26040"
                     /old_locus_tag="G9W35_25925"
     CDS             2889..3869
                     /locus_tag="G9W35_RS26040"
                     /old_locus_tag="G9W35_25925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019445.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element ISKpn26 family transposase"
                     /protein_id="WP_032072169.1"
                     /translation="MSHQLTFADSEFSTKRRQTRKEIFLSRMEQILPWQNMTAVIEPFY
                     PKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTT
                     IMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPE
                     MHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAG
                     YQGAPQREELTEVDVDWLIAERPGKVKTLKQHPRKNKTAINIEYMKASIRAKVEHPFRI
                     IKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRVDQMIRQWERSQ"
                     /name="IS5-like element ISKpn26 family transposase"
     gene            <4017..4286
                     /locus_tag="G9W35_RS26045"
                     /old_locus_tag="G9W35_25930"
                     /pseudo=""
     CDS             <4017..4286
                     /locus_tag="G9W35_RS26045"
                     /old_locus_tag="G9W35_25930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546749.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /name="EcsC family protein"
     gene            5397..5591
                     /locus_tag="G9W35_RS26050"
                     /old_locus_tag="G9W35_25935"
     CDS             5397..5591
                     /locus_tag="G9W35_RS26050"
                     /old_locus_tag="G9W35_25935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_001041631.1"
                     /translation="MNKQQQTALNMARFIKSQSLTLLEKLDALDADEQAAMCERLHELA
                     EELQNSIQIRFEAESETGT"
                     /name="Rop family plasmid primer RNA-binding protein"
     ARG             complement(1919..2790)
                     /name="CMY-136"
                     /gene="CMY-136"
                     /gene_name="CMY beta-lactamase"
                     /tool="rgi"
                     /drug_class="cephalosporin; cephamycin"
                     /identity="99.31"
                     /coverage="76.12"
     Typing          complement(4883..5138)
                     /name="MOBF"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="91.085"
                     /coverage="89.0"
                     /evalue="2.7e-93"
     Typing          complement(5263..5361)
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="98.0"
                     /coverage="100.0"
                     /evalue="1.35e-41"
     Typing          complement(5672..5757)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="97.701"
                     /coverage="100.0"
                     /evalue="1.86e-34"
     Typing          5779..6328
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.471"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aaagcgccac tggcagcagc cactggtaac tggacaaggt ggattgagat attaagagtt
       61 cttgaagtgg tggcctaact gcggctacac tagaaggaca gtatttggta tctgtgctcc
      121 accaagccag ttacccggtt aagcagtccc caactgactt aaccttcgac taaaccgcct
      181 ccccaggcgg ttttttcgtt tactggcagc agattacgcg cagaaaaaaa ggatctcaag
      241 aggatccttt gatcttttca tcactcctac ttcacggaca acaatgatat cggcatctcg
      301 cccgttgaat cactgaattc tcccaaggta agatcccaaa acagaccact tacaaaaagt
      361 aggctacaga ttgattcata agggattttt acatgcatct tgaagaagaa gatctgcgcg
      421 ctttagaaag agccgtagaa ttattagaac aagatacaat tacagaaaca ctaacccaat
      481 tagttggaac cccaatagat tacttaatga gtaaacttcc caaaggagca gaaaagaaaa
      541 tttatagcct agtagaaaaa tctctcaaca aagctgctaa tgcagcctta tggagcctag
      601 acaatgaacc taaccgaata gcatcaacta agacaaataa gttctttgct gccttatctg
      661 gagccattgg tggtgctttt ggcttttctg cattagcaat tgagttacca gtttcaacga
      721 caattatgct tcgttcaatt gcggacatag caagaagtga aggttttgat ctagatagga
      781 ttgatacaaa actagagtgt ttagcggtgt tttccttcgg aggaccatct gaggacgatg
      841 atgcagttaa tactgcatac tatgcaacaa ggaatttgac tgctgagatc gtacaagatt
      901 tatccaaaga aatttctaac attgctgtca agaacgctgc ttcaacacaa acaggaaaat
      961 ggttagggag cctgatatgt cctggatcgt tttattaatt gcaggtttgc tcgaagttgt
     1021 ctgggcgatt ggcctgaaat acacccacgg ttttacgcgt cttacgccaa gcattatcac
     1081 tattgcggcg atgatcgtca gtatcgccat gctctcttgg gcaatgcgca cgttgcctgt
     1141 aggaaccgct tatgcggtct ggaccggtat tggcgctgtt ggggcggcca ttacagggat
     1201 tttgctgctg ggtgagtctg ccagcccggc acgtttgctg agccttgggc tgatcgttgc
     1261 tggcattatt ggtctgaagc tgagcactca ctaagcgcca ggctgtttca cccaaatcag
     1321 tttattcact tcaaaccctt cccgggtcgc gatggctaac atttgctgtt tcatttcatc
     1381 tgaaatagta ggggtccgtg aaaggatcca caggtagtcg cgatccggac cacaaaccag
     1441 cgcgtgacga tattcccggt cgagtgcaat tacgttatac ccgccataga aggggccgaa
     1501 aaaagaaacc ttaagcgcgg ctctgcttgg gtcgccggtg aaataggctt tcccttccgt
     1561 tttctgccac atctccctgt cagggttata gcccttgtta ataacgttga tgccgccgtc
     1621 gtcgcgcaag ctgtatgttg cggtcacttt atccaatccg cgctcgaaac gatggtcgaa
     1681 gcgcgcaatt tcataccagg ttcccagata gcgtttggca tcaaagttat ttaccacggt
     1741 aacgcctttc ggcggtgtcg gggagctaca cgcgacaacc aggaatgcag ccgtaactgc
     1801 agcaacgacg ggcaaaatgc gcatgggatt ttccttgctg tatttttgtt aagtgtagat
     1861 gacaacagga aaaaaagaga aagaaaggag gcccaatatc ctgggcctca tcgtcagtta
     1921 ttgcagcttt tcaagaatgc gccaggccgc ctcgacacgg acagggttag gatagctttt
     1981 gtttgccagc atcacgatgc caaggttttt ttctggaacg aaggctacgt agctgccaaa
     2041 tccaccagtg gagcccgttt tatgcaccca tgaggctttc actgcggggg cgggcgggtt
     2101 tacctcaacg gcgggaagcg ctgccaatgc cactttgctg tcgctgccgt tgatgatcga
     2161 atcagctttc agcggccagt tcagcatctc ccagcctaat ccctggtaca tatcgccaat
     2221 acgccagtag cgagactgcg caagcgcaat gccctgctgg agcgttttct cctgaacgtg
     2281 gctggcatcc atgttggcct gaacccagcg ggccatatca ataacgctgg atttcacgcc
     2341 ataggcttcg gcgtcaagtt gtcccggaga aacgtgtacg ggcttccctt cgcgatagcc
     2401 ccaggcataa tctttttgtt cgttctgcgg aaccgtaatc caggtatgcg ccagttttaa
     2461 tggttgcagg acgcgtctgg tcattgcctc ttcgtaactc attcctgagg gtttcaccgc
     2521 cagcgcgcca aacagaccaa tgctggagtt agcgtaaagt cgcttagcgc ccggagtcca
     2581 ttgcggctgc cagttttgat aaaaatgcag taatgcggct ttatccctaa cgtcatcggg
     2641 gatctgcagc ggtaggccgc ctgccgtata ggtggctaag tgcagcaggc ggataccctg
     2701 ccactgtttg cctgtcagtt ctggccagta tttcgtgacc ggatcgctga gcttaatttc
     2761 gccgcgggcg atagcatcgc cgcccaacac gccgttaaac gtcttactaa ccgatcctag
     2821 ggaaggtgcg aacaagttcc tgatatgaga tcatcatatt catccggagc gcatcccaga
     2881 gggacatcat gagccatcaa ctcaccttcg ccgatagtga attcagcact aagcgccgtc
     2941 agacccgaaa agagattttc ctctcccgca tggagcagat tctgccatgg cagaatatga
     3001 ccgctgtcat cgagccgttt tatcccaagg cgggcaatgg ccgacggccc tatccgctgg
     3061 agaccatgct gcgtattcac tgcatgcagc attggtacaa cctgagcgac ggtgccatgg
     3121 aagatgccct gtacgaaatc gcctccatgc gcctgtttgc ccgattatct ctggatagcg
     3181 ccctgccgga tcgcaccacc atcatgaatt tccgccacct gctcgagcag catcaactgg
     3241 cccgtcaatt gttcaagacc atcaatcgct ggctggccga agcaggcgtc atgatgaccc
     3301 aaggcacttt ggtggatgcc accatcattg aggcacccag ctctaccaag aacaaagagc
     3361 agcaacgcga tccggagatg catcagacca agaaaggcaa tcagtggcac tttggcatga
     3421 aggcccacat tggtgtcgat gccaagagtg gcctgaccca cagcctagtc accaccgcgg
     3481 ccaacgagca tgacctcaat cagctgggta atctgcttca tggagaggag caatttgtct
     3541 cagccgatgc cggctaccaa ggagcgccac agcgcgagga gctgaccgag gtggatgtgg
     3601 actggctgat cgccgagcgt cccggcaagg taaaaacctt gaagcagcat ccgcgcaaga
     3661 acaaaacggc catcaacatc gaatacatga aagccagcat ccgtgccaag gtggagcacc
     3721 cgtttcgcat catcaagcgg cagttcggct tcgtgaaagc cagatacaag gggctgctga
     3781 aaaacgataa ccaactggcg atgttattca ccctggccaa cctgtttcgg gtggaccaaa
     3841 tgatacgtca gtgggagaga tctcagtaaa aaccggaaat aacgccagaa atggtggaaa
     3901 aaatagccta aataggctga ttcgatgtgt ttgcgggaaa aaaatcggcc cagatccgcg
     3961 aaattttaat caacgagtca gcttgggaag aaatgacctg cttattcgca ccttccttag
     4021 cttcgttaat agaaaaagtt gcgacaagat ttggtatagt tattacagaa aaaatggcag
     4081 ctcaagctgc tcctgttatt ggagcactgg ctggagccac attaaacacg atgtttaccg
     4141 actattatca agatatggct cgaggtcatt ttattgtcaa aagacttgag agaaaatatg
     4201 gtgatgaatt gataaaggct gaatatataa aaatctcaga taaactcacc aatcagaacc
     4261 aacggaagca tttgaacagc aactaacggt ttcactaagt gcatagcacc gttatggcca
     4321 ggtgctatgg agggtgtcaa ctcacgaaca atcacacaaa caacaaaatt atttatgatt
     4381 ttattttaaa cattatattc gcaaaaactg cattaatgaa attggctttt tttgaatcaa
     4441 ctaaaacaga gccacaattt gggcactgac taaaagcatt ccccccatca actaaaacat
     4501 cgctacattt aggcacagtt ttacaccaat ggcatgataa acatttatag gtcatagcca
     4561 ttctaatcat taccaatttc aactccacgc acaaaataaa tagttaaccc agcatctacg
     4621 aatatcaatc atatttacca taatcccgta ttgcgcgcac cgctaaaacg cgctgaacgc
     4681 gattctgccg caaacaccgc aaaaagagat gttttccccg gggtaaaccg gaaaaatgcg
     4741 tcaggctcgc tttcagctca ctgcatagct atgcatgaaa gtgaatgacg atcggtttgg
     4801 gcgcatacag tgcccatgag acacattttc ggacattttc agttcgtgaa tccctgactc
     4861 attgctacat atctgaacag acacccctgg cagcgccccc aggggcgtcc tgtaaaaaaa
     4921 cacaccgcgc agctagcagc acccctaata taagatgatg ttttttatga aaatagtcag
     4981 taccacccct aaaaagcggt gtcggcgcgg tgttgtagct gcgccaacac cgctttttta
     5041 aatatcacaa agagagcaag aagaactaat ttgtcataac tctctattta taaagaaaaa
     5101 tcagcaaaaa attgtttttg cgtggggtgt gggcatttca ggcatgagaa cagactcgcg
     5161 tttttccgga gtatcagcgg aattattgat taagaaacac tcgacgcaga gcgaaatttt
     5221 atgcaacagc ggctgcactg cacagggatt atttatcagt tgatatgctg tgccatgata
     5281 cgtcctaaag aaacaggaca ggatgtgcaa ttgtaatacc gtcgcccgca acgtcttaca
     5341 attaccacct gctcagggtc cccccgacac ccggaactga cggagaacaa cggaaggtga
     5401 acaaacaaca acaaactgcg ctgaatatgg cgcgatttat caaaagccag agtctgacac
     5461 tgcttgaaaa actggatgct ctggatgctg acgaacaggc ggccatgtgc gaacgactgc
     5521 acgaactcgc agaagaactc cagaacagca tccagattcg ctttgaggcc gaaagtgaaa
     5581 caggaacata acgaagctga cggaggcggt cacggctttc ccgtgggcgt tttcgtcagc
     5641 agacaagccc gtcagggcgc gtcagggggt tttagcgggt gtcggggcgc agccatgacc
     5701 cagtcacgta gcgatagcgg agtgtatact ggcttaacta tgtagcatca gtgcagatga
     5761 taagaaaaga gcaccatatg cgatgtgaaa taccgcacag atgcgtaagg agaaaatgcc
     5821 gcatcaggcg ctcttccgct tcctcgctca ctgactcgct acgctcggtc gttcggctgc
     5881 ggcgagcggt gccggctcac tcaaaggcgg taatacggtt atccacagaa tcaggggata
     5941 aggccggaaa gaacatgtga gcaaaaaggc aaagggcaac gaaaggccgc gccgctggcg
     6001 tttttccata ggctccgccc ccctgacgag catcacaaaa atcgacgctc aagtcagagg
     6061 tggcgaaacc cgacaggact ataaagatac caggcgtttc cccctggtgg ctccctcgtg
     6121 cgctctcctg ttccgaccct gccgcttacc ggatacctgt ccgcctttct cccttcggga
     6181 agcgtggcgc tttctcatag ctcacgctgt tggtatctca gttcggtgta ggtcgttcgc
     6241 tccaagctgg gctgtgtgca cgaacccccc gttcagcccg accgctgcgc cttatccggt
     6301 aactatcgtc ttgagtccaa cccggtaaga cacgac
//
