LOCUS       NZ_CP048782             9294 bp    DNA     circular CON 22-DEC-2023
DEFINITION  Klebsiella pneumoniae strain EGKP7 plasmid pEGKP7.4, complete
            sequence.
ACCESSION   NZ_CP048782
VERSION     NZ_CP048782.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14082726
            Assembly: GCF_017161485.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9294)
  AUTHORS   Hamza,E., Dona,V., Elhariri,M., Elhelw,R., Hamza,D. and Perreten,V.
  TITLE     Klebsiella pneumoniae -Carbapenamese-producing, complete sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9294)
  AUTHORS   Hamza,E., Dona,V. and Perreten,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2020) Institute of Veterinary Bacteriology,
            University of Bern, Laenggassstrasse 122, Bern 3012, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology :: Oxford Nanopore MiniION and Illumina
            NovaSeq 6000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/22/2023 17:16:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,727
            CDSs (total)                      :: 5,603
            Genes (coding)                    :: 5,457
            CDSs (with protein)               :: 5,457
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 54 of 146
            Pseudo Genes (incomplete)         :: 85 of 146
            Pseudo Genes (internal stop)      :: 29 of 146
            Pseudo Genes (multiple problems)  :: 19 of 146
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048782.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="EGKP7"
                     /isolation_source="chicken-internal organs from poultry
                     farm"
                     /host="chicken"
                     /db_xref="taxon:573"
                     /plasmid="pEGKP7.4"
                     /geo_loc_name="Egypt:Giza"
                     /collection_date="2015"
     gene            join(9276..9294,1..281)
                     /locus_tag="G4D19_RS28505"
                     /old_locus_tag="G4D19_28985"
     CDS             join(9276..9294,1..281)
                     /locus_tag="G4D19_RS28505"
                     /old_locus_tag="G4D19_28985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(343..720)
                     /locus_tag="G4D19_RS28510"
                     /old_locus_tag="G4D19_28990"
     CDS             complement(343..720)
                     /locus_tag="G4D19_RS28510"
                     /old_locus_tag="G4D19_28990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            789..968
                     /locus_tag="G4D19_RS28515"
                     /old_locus_tag="G4D19_28995"
     CDS             789..968
                     /locus_tag="G4D19_RS28515"
                     /old_locus_tag="G4D19_28995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(996..1526)
                     /locus_tag="G4D19_RS28520"
                     /old_locus_tag="G4D19_29000"
     CDS             complement(996..1526)
                     /locus_tag="G4D19_RS28520"
                     /old_locus_tag="G4D19_29000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(1533..2264)
                     /locus_tag="G4D19_RS28525"
                     /old_locus_tag="G4D19_29005"
     CDS             complement(1533..2264)
                     /locus_tag="G4D19_RS28525"
                     /old_locus_tag="G4D19_29005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(2264..4228)
                     /locus_tag="G4D19_RS28530"
                     /old_locus_tag="G4D19_29010"
     CDS             complement(2264..4228)
                     /locus_tag="G4D19_RS28530"
                     /old_locus_tag="G4D19_29010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(5709..5858)
                     /locus_tag="G4D19_RS28535"
                     /old_locus_tag="G4D19_29015"
     CDS             complement(5709..5858)
                     /locus_tag="G4D19_RS28535"
                     /old_locus_tag="G4D19_29015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(5943..6200)
                     /locus_tag="G4D19_RS28540"
                     /old_locus_tag="G4D19_29020"
     CDS             complement(5943..6200)
                     /locus_tag="G4D19_RS28540"
                     /old_locus_tag="G4D19_29020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(6210..7895)
                     /locus_tag="G4D19_RS28545"
                     /old_locus_tag="G4D19_29025"
     CDS             complement(6210..7895)
                     /locus_tag="G4D19_RS28545"
                     /old_locus_tag="G4D19_29025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            8298..8717
                     /locus_tag="G4D19_RS28550"
                     /old_locus_tag="G4D19_29030"
     CDS             8298..8717
                     /locus_tag="G4D19_RS28550"
                     /old_locus_tag="G4D19_29030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            9023..9286
                     /locus_tag="G4D19_RS28555"
                     /old_locus_tag="G4D19_29035"
     CDS             9023..9286
                     /locus_tag="G4D19_RS28555"
                     /old_locus_tag="G4D19_29035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     BGC             1210..9294
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          5028..5606
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(1537..2264)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 ggaagcaggg agccatcgag gatgtaacga cgctgtttga ctatatcgcg gaaaattcat
       61 ccctgtggga tgcgcagaac gttaccgacc gggttctcgc tgcggcggac aaactggccg
      121 acttcccgcg actctatgaa gtggactcac gctatggcga ggacgttcgc cggatcagtc
      181 tgatgggaca gcatgtcctc tatgatgttg atgaccagac cagaaaagtc cgggttctgg
      241 ccgtggtcgg ccagcgccag aatccccata ttgttctcta ataaccggtg acggggacgc
      301 aattcattgc gtggccgtcg ccggttggac aagcacagcg cgtcagcgtt ttccccacgg
      361 ccaccaccgg cgcggtgttc cggccggggt ctctgctgtc tccggtttgt gttccagcag
      421 tctcatggac tgcatttcct gccgtagccc ggccacctcc tccctgagtg cttttatctc
      481 cgcgatcaac gcgtcggagg ccattttttc agtctcaccc gacagtctca actcgtcccg
      541 ctcgtgagtc tcatcctgtc ttaactcacc gtacacccgg ataagctcgc tggtatccac
      601 cacccggccg ccatcagctt ccgtacggta tgatacgcgg cctttcgcca tatcccgata
      661 cagggaactt cgggctttac ccgtcagttc cgtcgcctgt ctcaccgtca cccacgccat
      721 tgtctcaccc cgctattttt gagacagtat acctgacagg cgcacaccat gcccggaagg
      781 aaagaatcat gacaaaacag gaaaaaacag ccctcaatat ggctaaattt attaaggagc
      841 agtcgctgct attgctcgat aaactgaatg agctggatat ggataccccg gccgacatgt
      901 gcgagcggct acacgaggat gcggaaacac tctggcaggt gatgcgggat aagctcgggg
      961 aggaataaca gcaccggcat ggccggtgct ggcatttatt ttttgccgaa cggccaccac
     1021 cggcgggcag gtttgtcctc cggcagttca ggtaccggca cgttaaaata gcggctgtta
     1081 tattcccgca tcagctccgc tttcagcttc tcgttcaccg cgctttcccc gtgccgctca
     1141 ctcaccacgt caatcatcgc gttaatctgc tccggtgagc acttcccggc atcaaccacc
     1201 tgcacaccgt tctcgatggc gaaccgctcc accttgcgat agaggtaatc acacagcttc
     1261 attcctgtgg gtttgttccg ttcccattgc ggatttttac cagtgaaaaa gtacgtggct
     1321 ttttcgtcgc tgttgagccg ctcgtcatac atcccgatgg atttcatcat cgccagatgc
     1381 tgggcccggt cgacaaaaca gaaaacatac gccccggtct gccaggcgag caccaccata
     1441 tcttccagat gctcgctggt cggcatgatg cagcgctcgc cgttccggtc ctccgcgtct
     1501 tcaataaata ccatgtacag cgccataatc cctcactccg ttgtcataaa tttaaagcac
     1561 gcaaacaacc gttcacgatc cagctctgcc gttttgcggg cctcgccggt ctgtgggttc
     1621 acgatttcat ccaccgacag gattgcccgc tgcaccctga cctgcgtcgc ccggtccggg
     1681 cagatgtacc agatttcatc gatgccgtta gctttgcggt tgaacagata cccggacacc
     1741 acttcctgat accggcgacg gctcttgacg gtgcgctcca cctcaaacgc caccgtttta
     1801 ccgtccagct ccgccagggc gtccggcact ttcatgcctt taagactcag acggtgcaga
     1861 atgcgccagc cggtggcccc tctggcttcc atatcaaggc gcagggattg cacggccagc
     1921 cggtgcggca gatgtgctgc cgacaccctt gacggctgaa acggaataac atccgccagc
     1981 ggttcgtcct cgtcgaacga gaacgccacg ccatgcggcg tcagccccca cacgctgacc
     2041 tgacggccgt ccaccggata tttggtccgg accagcagcc ctttcgccac caggctgtcg
     2101 aggaagcggt agaccggctg caccgccgca atccccagcc gccgcgcaac cagctccgcc
     2161 gtggaacaca gctcttcccg caaccagcgc agggtcagcc gggttttctc cgcgttccgc
     2221 gcctgtcgtt tcgcgtggct gacgttgtac agctccagcg ccatcagtaa atccccgcaa
     2281 aatcatcatc cgctttcggc ccgccgccgt cggccggggg ccggaactcc gccaggggat
     2341 cggttttcgc cagcaccggg aaacgctgca acgggatttc ccggcgctca acccgcagcg
     2401 gactgctgaa cgccatccgg gccacaccca gcccggtcat gaccgcgaac ccgtccggca
     2461 ggtgttgcag ggtgttcacg tcaaacagcg gccgcgcctc cttctggatg aagctgtccc
     2521 cgctgatatg ctccacgttc cccgcctccc ggctggcacg gcggcgctcc acgtccaccc
     2581 tgatttcccc ggtctgcccc gccgcccact gcgcggactc caggctggcc gcccggtaaa
     2641 accagcggat cggcgtgtta tccagtaccg tggttttcac aaattcagcg ggcagatcct
     2701 gcccgcactg cccgaaatcg cccagcgact ggtgcgcgag caacagattg cagtcccggc
     2761 tgcgcagcgt ccccagtgcg ttcagtacat acttcgacag cagatattta atttcatcga
     2821 gcatcacgct gacgtgtggc cactcccgga actcgtcccg cgcaatgatg atttgcgcgc
     2881 agcgggcaaa cagcattttt tgcacacgga tcaccgcctc gtcgtccatc gagccgataa
     2941 cgtacaggca gccgccgccg ttgataatcc ccgccacatc gatgccactg tccgtctgca
     3001 ggacgctcag gtcagcgacg ttttccagcc tagtgatcaa ccccttcacg tcctttttca
     3061 gggcctccgg cagcgcgtac gccgccgcca gcacctgctg aatgtttgcc ccctgcggaa
     3121 actgctccgc aatcagcttc gccgctttct gctcgctgat gcggtagtgg tccgccacgt
     3181 cgccggtctc gcccaggtta agcccggcaa tcagcaggtt tttcagcgcg tactggtcga
     3241 gatcgcggaa cagattcagc tgcgccggtt tccccggccg cagatccagc agggtgaagt
     3301 ccggacagtg cgcccggaag acgtgcggcg cccatgcgtc ccctttgggg tcgaagtaca
     3361 ccaccgcgtc cccgaaatcg cgtacgcagc gaatgagcgc gttggtggcc atcacgctct
     3421 tgccgctccc gggcaggccg aggatctgaa tgttggtctt gcgccaggta tcacgcggaa
     3481 ccagcaccgg cttgccctgc tcatccttac ccagaaacac cgcctgctcc tgccgggcct
     3541 gctccgagga aaaatcggcc agcgcattaa ccggtaccgg ctccccgaaa tgcaggtggc
     3601 gcacgtcggt catctctcct gtccgctggc tgctgcgccg gctctcctga ttcagtttcg
     3661 cgttcaccgc ctcgtcagca gccgcaaaat gaccgtcaag cagcaggaac gccagcagcc
     3721 gcgccaacac aatcccgaca gccagcccgc ccgcgcacca ggcaatcccg aacaggttag
     3781 ccggctgcag caggtaataa tctgcgtttg cgtagaggtc cggacgcagg acggtttctc
     3841 cccagctctc gataaacacg gcgacaacca gcccccccag aagggccaga ccggccgcgc
     3901 cggtcagcca gtacgcgtag ttccagacat gtcgacgtgc cctgaccatc cgcccgggcg
     3961 aatccagcga ggccagcacc gaaaatggcg ctggccgttt attatcgcgc ttatagcgat
     4021 cggcatactc ccgtcgctcc ttatgactca gccccacaaa acgcatccgt ccggcccaaa
     4081 gttcagccag accgaaaaac aggccgataa ctaggaaagc cccggccaga ccgtaatact
     4141 cctggtacag ccagctgacc cacggataaa tctgccgggc cagctccgga atgtgccact
     4201 tccaggcaag cgaatccgta ttaaacatgt tctctctcct tcagacgatg gtttgccggc
     4261 gtgatgtgca gcccccgctg cacaagccgc ggacatgccc caaggcatgg cggcggcggt
     4321 cacgtccgtg gtgattgcgt tcagctttca ccacggaggc cagcctcttt ccgccccatg
     4381 cggaaaaggc gcagccccgg aggaacaacg agcacgcccc agcgtgtgag aggaaaaggc
     4441 ggcaccccag tgcggtcttt tccggtgttc cggcccccgt cagagttcgc catagcgagc
     4501 ggctgaccac ccgcaaaatc aggagcagct ttgctgcttc gccaggtgcg tccagcaccg
     4561 tggatttttg tgggtggtca ggcgtgagcc tgacgggggc cgggtgaatt tctggcgtgg
     4621 ccggcgtcca gccggacgga gccagaaaga gggggagaga ccgtgcgtcg gtggcgtcca
     4681 gccagcgtaa gcaggggata tccccctgag gtcagccacg ccctcgcggg gatgacctgt
     4741 atttctccgt aaggagaaaa aagcaacaga gataggttaa cgtaaaatgt tcagcgaaaa
     4801 accgatatga ttcacctatc ctggtaattt attatcaggg aatataaaga cttaatcagg
     4861 ggacaatatg ccacatcagc gcgtccggtg tccgtcttgt aggtgccggg gaaattgcgc
     4921 ctcctcgctc actcggtcgc tacgctccgg ccgtgagact gcggcgggcg ctgcggacac
     4981 atgcaaagtt acccacagat tccgtgaata agcaggggac taacatgtga ggcaaaacgg
     5041 caaggccacg caggtggcgt ttttccatag gctccgccct cctgactgag ttcacataaa
     5101 cagacgcttt ttcggtgcat ctgtgggagc cggtggctca accatgaatc agtcaggagt
     5161 ggcgaaaccc gacaggactt aaagatcatc accgtttccg atgaatcgct ccctcttgcg
     5221 ctctcctgtt ccaaccctgc cgtttcccgg atacctgttc cgcctttctc ccttgcggga
     5281 agtgtggcgc tttctcatag ctcacactct ggtatctcgg ctcggtgtag gtcgttcgct
     5341 ccaagctggg ctgtaagcaa gaaccccccg ttcagcccga ctgctgcgcc ttatccggta
     5401 actgttcact tgagtccaac ccggaaaagc acgcaaaacg ccactggcag cagccattgg
     5461 taactgggag ttcgcagagg atttgtttag ctaaacacgc ggttgctctt gaagtgtgcg
     5521 ccaaagtccg gctacactgg aaggacagat ttggttgctg tgctctgcga aagccagtta
     5581 ccacggttaa gcagttcccc aactgactta accttcgatc aaaccacctc cccaggtggt
     5641 tttttcgttt acagggcaaa agattacgcg cagaaaaaaa ggatctcaag aagatccttt
     5701 gatcttttct actgaaccgc gatccccgtc agttcagagg aggacgatgg tgccaccgtt
     5761 ccaccctgaa catcccggat atagtttgcc tgacatgcga ccagaagaaa gcctgaaaaa
     5821 atcaatataa aaagaaaaac aacctttacc tttttcatat accttccctg tatttaaaaa
     5881 ccccggtatt catccctgaa caccggaagt ctgtatttca aatcatcctt gataactttt
     5941 gcttaccagt taccatcccg gtaaacaaag gatacaaagt aatcaaattt actaatatcg
     6001 attacatttt taaagtgtgg ctgtaatatc gaaacccatg atttttcaac atcaaaccaa
     6061 ccattattaa tattatcctt taaaggcatc cccagacttt caatgacaga accatcatca
     6121 ccgaagtctt ttgagtattc accaccttta aactcttcgg ttttcttatc aaaccaatga
     6181 atatgtaatt taagccccat atttacctct taaagatatt ttttaatgtt tcgttttgga
     6241 tccggccctt taacctgctt acccgttttt ggatcgaatg ccccgaggtg ttcgccatca
     6301 ctggcgcggt acccttcaag ctcaccgtgc tgggaatccc attcataaat tttacgcttt
     6361 ttatcaccat accatcgggc ccgcttacca ccaccacctt gtttaggggt tttaggttta
     6421 ccctctttca actctcccaa ccccttaata tcttcagtct tgggatcagg aaaataatca
     6481 tggccgtaat ctttagttcc cttacgaggt tttttctttt cctcatttaa tttattttct
     6541 gcatccttcg cttttttctc cttttgtttc cggctctcca tcgccccgga aagcgcagcc
     6601 ttatccctgg ataaggattc attcatttcg tttaaagatg tctgggcagc ttttaatttc
     6661 tcattctgat tctgaatatc cttatcaaga tagcgaacct gatcctgcca cccggagcca
     6721 tattcatgag gcgggttata agtcacaaaa tcatctttat ttgcctctgc ctcttttacc
     6781 tttttatcgg cttcctgaac agcagccctt gcaccgggga tcgccttctc tgtcgatgca
     6841 atgcgactgt ttaaggtcgc aatattttta tcttcagcat ccagctcagc tttcgcttta
     6901 tcatactctc ttttcagccc ctcttccggg tgagcagcgt cccatgcctg ctggcgacgc
     6961 ttttcttcct ccagacgctg ttttacctgt gccggagtaa gaacatccgt caccgacaca
     7021 tagaccggtt tctgtccgct ctctttcggg aaacgaataa cggcctcacg ggagttacca
     7081 ccggccgtaa aaccagccgg acgtgaatca cctttttcag caataatgcc ttttggcggg
     7141 gctttcgcgg ccggaacacc tttaggtacg ctcacctgca gagacgggag acccggaatc
     7201 gacacactga atacccccgg acgttttgtc ggtttcgcat ccaccacagg aacactcatt
     7261 ggccggccgg tgacaaccgc aatatgctgc cgctcgtcct tcacaatatc cgccacacgt
     7321 ttagtgacgc tgaccgtcgc ctggtccagc ggcagggagc tgaccggcgt ctccgttacc
     7381 gtgtctgccg gcaatgacgt cacgattttt gacatcattt tcggatcatc ttttgctatc
     7441 tcagaaggca gcactccgta aatcgcaatc ccccacagac caaacttaaa cggacctttc
     7501 agggcagcca gcacatcagc aacagcggcc gacaacgcat cgccggaaac ggataaagcc
     7561 agtccttcag cccccggagt ggccagggca ggcagaccga aggccatcgc ggtggccgaa
     7621 gactgtccgc caccagagct cccgctatga ttgccgctgt taccgccatt accaccgggt
     7681 ttactcccgc cgttaccaaa ctcccccggg ttatagttat gaatatcccc gttaggtgta
     7741 tgcgtcgtac cccagcccgg cccgctgttt ggatccgtac caccacctga tgaagggcca
     7801 cctttacctg atgtaccgtt cacattccca ctggcctgac caccattgtg tcccagacct
     7861 gaattacccg gacctcgtcc gtctccgcca ctcatatact tttcctcttt gacttttaaa
     7921 acaataaact aaaataaaat actgtacata taaccactgg ttttatatac agtacaaaaa
     7981 ttacgctgcc ttgtttttca tgtcaagtct gtaaatttgc gtttttgtga aaatgatcaa
     8041 aaaaacagcc actcacacca tgcgcaatcc cctccagatg caacaaaaac cagcacaaac
     8101 ggcgccgttc tccggcctca gtatgtttta ctgaaatcat tatatgagat accagaaagc
     8161 cccctccggg acaggaaaag aaacgggggg tctggttcgg gttgttcggt cactgaacac
     8221 ggtcagaaac tgatgataag atagcctgcg gatatataac tcaatgagaa aaaagaatta
     8281 aaggtaagga gacgctcatg agacgttccg gcagcaaact gtgtcttatc gccatgataa
     8341 cagcgacagc aactctcact gcctgtgctc caaagggcag cgtggaacag catacccggc
     8401 attacgtata tgcttcagat gacggttttg atcccaattt ttccacccag aaagctgaca
     8461 caacacgaat gatggtgcct tttttccggc agttctggga tatgggcgca aaggataaag
     8521 cgaccggaaa atcacggagt gatgtgcagc aacgcattca gcagtttcac agtcaggaat
     8581 ttttaaactc actccaaggc acaacacaat ttgcgggtac cgattaccgc agcaaagacc
     8641 tcacaccgaa aaaatcaagg ctactggctg acaccatttc agctgtttat ctcgatggct
     8701 atgaaggcag acagtaagtg gatttaccat aacgcgtcat tacgcgcacc gctcagacgg
     8761 gctcagggcg tttccggcgg ctacgggata aaacaggcaa caaccccccc ggaaaactgc
     8821 cggaaacgcg cccgataaat tttatcctaa tgcatgccta tgcacgcaac tgcatggcat
     8881 atgttttgac gtaaaatgga tgccgtaagc ccttttttac cgactttctg cttcatcagc
     8941 ctgactgaca cgaccatatt ctttcagacc gccccctgct aaacttcctt catattgccg
     9001 cattaacccg ggaggctccg caatgagcaa cactacacac tacgaaaacg ccaactttct
     9061 tcgggaactg gctgaaagcc tgccccgcat actgccggaa ggtggcccgg acaaagctgc
     9121 gctgttgcag cgactggcta acgaagaact ggcccaggca gagtatgaag atcaggttcg
     9181 cgccaaagtg accgccgccc gtgctgacac gcgtccgggt atgaccacgg aacaactccg
     9241 ccagcgcctg catggccgtt atcaggaact gcgcgatgcc gtatgacgtg gaat
//
