LOCUS       NZ_CP048645            28040 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Staphylococcus aureus strain SR153 plasmid pSR02, complete sequence.
ACCESSION   NZ_CP048645
VERSION     NZ_CP048645.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN13008646
            Assembly: GCF_010669265.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 28040)
  AUTHORS   Chen,Y.
  TITLE     Dissemination of the Same cfr-Carrying Plasmid among Methicillin
            Resistant Staphylococci in Hangzhou, China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 28040)
  AUTHORS   Chen,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-OCT-2019) Infectious Diseases, Zhejiang University, 3
            East Qingchun Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010669265.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 03:21:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,958
            CDSs (total)                      :: 2,879
            Genes (coding)                    :: 2,732
            CDSs (with protein)               :: 2,732
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 103 of 147
            Pseudo Genes (incomplete)         :: 42 of 147
            Pseudo Genes (internal stop)      :: 33 of 147
            Pseudo Genes (multiple problems)  :: 29 of 147
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048645.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..28040
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="SR153"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pSR02"
                     /geo_loc_name="China:Hangzhou"
                     /lat_lon="30.3 N 120.2 E"
                     /collection_date="2013-06-01"
                     /collected_by="Wu Dandan"
     gene            800..1336
                     /locus_tag="GAU34_RS14425"
                     /old_locus_tag="GAU34_14425"
     CDS             800..1336
                     /locus_tag="GAU34_RS14425"
                     /old_locus_tag="GAU34_14425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001829875.1"
                     /translation="MISNKLKSARLAKELTQSEVAKKLYVTRQTVSRWEQGKTLPNIYV
                     IQELSDLYDISLDELVVNTALENKEAKSMKNVNPFALFGAILFNVFLFSLIVIFFGGFL
                     LLSLFISLAMLFSPLILAIFVLTGVQEFNVIQLVMTVIFVVIGLLSIPLLKKVSVFLFK
                     FFKRYLKFNHKAIFY"
                     /name="helix-turn-helix domain-containing protein"
     gene            1490..1585
                     /locus_tag="GAU34_RS14430"
                     /old_locus_tag="GAU34_14430"
     CDS             1490..1585
                     /locus_tag="GAU34_RS14430"
                     /old_locus_tag="GAU34_14430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_014287283.1"
                     /translation="MSEIFVNIMTTAASGCLVALFAHWLRKRNDE"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            1998..2843
                     /locus_tag="GAU34_RS14435"
                     /old_locus_tag="GAU34_14435"
     CDS             1998..2843
                     /locus_tag="GAU34_RS14435"
                     /old_locus_tag="GAU34_14435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109600.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_001829879.1"
                     /translation="MDLVENCNTFLSFVTNRRMDKKKLYKSNPCKNRFCPMCAWRKARK
                     DALGLSLMMQHIKQAEDKQFIFLTLTTPNVTSEHLESEIKHYNQSFRRLSNRKHFKSIA
                     KGYVRKLEITYNKKRDDYNPHFHVLIAVNKSYFKDTKAYITQKEWLEMWRDVTGNSEIT
                     QVHIQKVKQNNNKELYEMAKYSGKDNDYLINQKVFDAFYKALKGKQVLVYSGLFKDARK
                     KLKNGELDYLKEVDPTEYIYQIFYTWNKKEYLASEIFDLTESEKQEINHQMIDEIEEEK
                     "
                     /name="protein rep"
     gene            complement(3692..4177)
                     /gene="lnu(A)"
                     /locus_tag="GAU34_RS14440"
                     /old_locus_tag="GAU34_14440"
     ARG             complement(3696..4177)
                     /name="lnu(A)"
                     /gene="lnu(A)"
                     /gene_name="lincosamide nucleotidyltransferase Lnu(A)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <4649..5125
                     /locus_tag="GAU34_RS14445"
                     /old_locus_tag="GAU34_14445"
                     /pseudo=""
     CDS             <4649..5125
                     /locus_tag="GAU34_RS14445"
                     /old_locus_tag="GAU34_14445"
                     /inference="COORDINATES: protein motif:HMM:NF013603.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            5285..6055
                     /gene="aadD1"
                     /locus_tag="GAU34_RS14450"
                     /old_locus_tag="GAU34_14450"
     ARG             5286..6052
                     /name="aadD1"
                     /gene="aadD1"
                     /gene_name="aminoglycoside O-nucleotidyltransferase
                     ANT(4')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            6335..7009
                     /locus_tag="GAU34_RS14455"
                     /old_locus_tag="GAU34_14455"
     CDS             6335..7009
                     /locus_tag="GAU34_RS14455"
                     /old_locus_tag="GAU34_14455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_044124596.1"
                     /translation="MNHFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <7067..7765
                     /locus_tag="GAU34_RS14460"
                     /old_locus_tag="GAU34_14460"
                     /pseudo=""
     CDS             <7067..7765
                     /locus_tag="GAU34_RS14460"
                     /old_locus_tag="GAU34_14460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /name="replication initiation factor domain-containing
                     protein"
     gene            7927..9306
                     /gene="tet(K)"
                     /locus_tag="GAU34_RS14465"
                     /old_locus_tag="GAU34_14465"
     ARG             7928..9303
                     /name="tet(K)"
                     /gene="tet(K)"
                     /gene_name="tetracycline efflux MFS transporter Tet(K)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9495..10721
                     /gene="mobV"
                     /locus_tag="GAU34_RS14470"
                     /old_locus_tag="GAU34_14470"
     CDS             9495..10721
                     /gene="mobV"
                     /locus_tag="GAU34_RS14470"
                     /old_locus_tag="GAU34_14470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016913210.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_049426404.1"
                     /translation="MSYSIVRVSKVKSGTNTTGIQKHVQRENNNYENEDIDHSKTYLNY
                     DLVNANKQNFNNLIDEKIEQNYTGKRKIRTDAIKHIDGLITSDNDFFDNQTPEDTKQFF
                     EYAKEFLEQEYGKDNLLYATVHMDEKTPHMHYGVVPITDDGRLSAKEVVGNKKALTAFQ
                     DRFNEHVKQRGYDLERGQSRQVTNAKHEQISQYKQKTEYHKQEYERESQKTDHIKQKND
                     KLMQEYQKSLNTLKKPINVPYEQETEKVGGLFSKEIQETGNVVISQKDFNEFQKQIKAA
                     QDISEDYEYIKSGRALDDKDKEIREKDDLLNKAVERIENADDNFNQLYENAKPLKENIE
                     IALKLLKILLKELERVLGRNTFAERVNKLTEDEPKLNGLAGNLDKKMNPELYSEQEQQQ
                     EGSVAKLNL"
                     /name="mobV"
     gene            10751..11425
                     /locus_tag="GAU34_RS14475"
                     /old_locus_tag="GAU34_14475"
     CDS             10751..11425
                     /locus_tag="GAU34_RS14475"
                     /old_locus_tag="GAU34_14475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            11733..12350
                     /locus_tag="GAU34_RS14480"
                     /old_locus_tag="GAU34_14480"
     CDS             11733..12350
                     /locus_tag="GAU34_RS14480"
                     /old_locus_tag="GAU34_14480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="WP_049394661.1"
                     /translation="MIQTIVTAAILYIATAVDLLVILLIFFARAKTKKEYRDIYIGQYV
                     GSVALIVVSLFFAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLITLFVFLILIFFLVFTAQKLSN
                     IPGVGEIVEKFSRWIMAVIYIALGLFIIIENDTIQTILGFIF"
                     /name="CadD family cadmium resistance transporter"
     gene            12369..12716
                     /locus_tag="GAU34_RS14485"
                     /old_locus_tag="GAU34_14485"
     CDS             12369..12716
                     /locus_tag="GAU34_RS14485"
                     /old_locus_tag="GAU34_14485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_002441960.1"
                     /translation="MSYENACDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKISVASTSHHLRLLYKNDVLDFYKKGKMAYYFIKDDEI
                     KEFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            12885..12986
                     /locus_tag="GAU34_RS14490"
                     /old_locus_tag="GAU34_14490"
     CDS             12885..12986
                     /locus_tag="GAU34_RS14490"
                     /old_locus_tag="GAU34_14490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000228874.1"
                     /translation="MVEALVHITTTVISGCIVALFTHWLRTRNNKKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            13368..13589
                     /locus_tag="GAU34_RS14495"
                     /old_locus_tag="GAU34_14495"
     CDS             13368..13589
                     /locus_tag="GAU34_RS14495"
                     /old_locus_tag="GAU34_14495"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002504105.1"
                     /translation="MAKYWKENQEGLLNDGEALTILMMLYNEHPYVVQLPCLNKQLQDD
                     NRYAQPTYTIYSTTKNRKENKRRIKNSI"
                     /name="hypothetical protein"
     gene            complement(13712..13861)
                     /locus_tag="GAU34_RS14500"
                     /old_locus_tag="GAU34_14500"
     CDS             complement(13712..13861)
                     /locus_tag="GAU34_RS14500"
                     /old_locus_tag="GAU34_14500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="WP_002504104.1"
                     /translation="MKTLNEKQLKDINGGKGIVGEVTGEVTSIGNAISNGWHDLKQSVA
                     DTTK"
                     /name="bacteriocin"
     gene            complement(13882..14025)
                     /locus_tag="GAU34_RS14505"
                     /old_locus_tag="GAU34_14505"
     CDS             complement(13882..14025)
                     /locus_tag="GAU34_RS14505"
                     /old_locus_tag="GAU34_14505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002504103.1"
                     /translation="METLNEKQLKDINGGRETGCSGDFVEDGIMCNIGQGIGKAINKVR
                     GK"
                     /name="hypothetical protein"
     gene            complement(14182..16338)
                     /locus_tag="GAU34_RS14510"
                     /old_locus_tag="GAU34_14510"
     CDS             complement(14182..16338)
                     /locus_tag="GAU34_RS14510"
                     /old_locus_tag="GAU34_14510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440725.1"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]; GO:0008233 - peptidase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_002504102.1"
                     /translation="MAIKFIRQYDEKDCGPTCLAMISQFYGKRVSIPRLREYAKTDKLG
                     TNLYGLVQAGKKIGIELTGVKADSFDDLKQAQLPVMVHIINQQGYDHYIIIEKIKNNTL
                     YIVDPAKGKYKLSSTEFGKYWTNIAVLIDKTDDFTTDNESPSYLNIFIDIFKNNYGKLL
                     FIAFISLFINIVGIVGALYFKLLTDHIIPSNVLKNLHIISFGILLLYIINALINYLRFQ
                     LILHLSLKIDVNLMKDYFYHVLHLPMNFFDTRKSGEILQRFMDTSKIREALSSSTVTLL
                     VDTFMIIIGAILLYMQSPLLLLITIIFIPCFIICSYTLRKPFEKYNQKVAEKDAELSSY
                     LIESFDGSNTIKSYQSEDDRFYIGTTKFNGIIENLLKLGRFSNIQLTVNNFLKLTISLV
                     ILWLGSYLVMTDSMTLGSLLAFNALTIYYLDPIERLINIQPTLQSSFVAARRIAEITDL
                     ETETELYTSKQPYTFKNNIRIENVNFQYGFRSVVLKDINLNIKKGQKVAIVGESGSGKS
                     TIGKLLNRYYTASEGNIMIDNYIIDDIDLSDLRKNIGYVSQNTFLFADTIKNNLLHGSN
                     KYKSDEDIVKACQLAESLDFIQKFPDQFNTMLEKEGANLSGGQGQRLSLARTFLKDPDI
                     YIFDEATSALDSLTENKIMEHIDLLTQHGKTVIIISHKLSTIKNADNIYVLNEGQIAEN
                     GTHDELIHLNGIYKNLWQLQMKID"
                     /name="peptidase domain-containing ABC transporter"
     gene            16566..17174
                     /locus_tag="GAU34_RS14515"
                     /old_locus_tag="GAU34_14515"
     CDS             16566..17174
                     /locus_tag="GAU34_RS14515"
                     /old_locus_tag="GAU34_14515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583537.1"
                     /translation="MIIGYARVSSVDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIVQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKNGKGLS"
                     /name="recombinase family protein"
     gene            complement(17426..18100)
                     /locus_tag="GAU34_RS14520"
                     /old_locus_tag="GAU34_14520"
     CDS             complement(17426..18100)
                     /locus_tag="GAU34_RS14520"
                     /old_locus_tag="GAU34_14520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_010775116.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYRIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQSPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <18158..18687
                     /locus_tag="GAU34_RS14525"
                     /old_locus_tag="GAU34_14525"
                     /pseudo=""
     CDS             <18158..18687
                     /locus_tag="GAU34_RS14525"
                     /old_locus_tag="GAU34_14525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /name="IS256-like element IS256 family transposase"
     gene            18744..19136
                     /locus_tag="GAU34_RS14530"
                     /old_locus_tag="GAU34_14530"
     CDS             18744..19136
                     /locus_tag="GAU34_RS14530"
                     /old_locus_tag="GAU34_14530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000393259.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYT
                     LLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACH
                     VYEKLGGKNDYKDEIVYVYDYEKGDK"
                     /name="GNAT family N-acetyltransferase"
     gene            19137..20576
                     /gene="aph(2'')-Ia"
                     /locus_tag="GAU34_RS14535"
                     /old_locus_tag="GAU34_14535"
     CDS             19137..20576
                     /gene="aph(2'')-Ia"
                     /locus_tag="GAU34_RS14535"
                     /old_locus_tag="GAU34_14535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="WP_001028144.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
                     /name="aph(2'')-Ia"
     gene            complement(20742..21416)
                     /locus_tag="GAU34_RS14540"
                     /old_locus_tag="GAU34_14540"
     CDS             complement(20742..21416)
                     /locus_tag="GAU34_RS14540"
                     /old_locus_tag="GAU34_14540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_010775116.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYRIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQSPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(21473..22039)
                     /gene="qacR"
                     /locus_tag="GAU34_RS14545"
                     /old_locus_tag="GAU34_14545"
     ARG             complement(21477..22039)
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.47"
                     /coverage="100.0"
     gene            22217..23761
                     /gene="qac"
                     /locus_tag="GAU34_RS14550"
                     /old_locus_tag="GAU34_14550"
     CDS             22217..23761
                     /gene="qac"
                     /locus_tag="GAU34_RS14550"
                     /old_locus_tag="GAU34_14550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QacA/B family quaternary ammonium compound efflux
                     MFS transporter"
                     /protein_id="WP_058342586.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVILAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGMASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="qac"
     gene            23966..24526
                     /locus_tag="GAU34_RS14555"
                     /old_locus_tag="GAU34_14555"
     CDS             23966..24526
                     /locus_tag="GAU34_RS14555"
                     /old_locus_tag="GAU34_14555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001077893.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(24849..25616)
                     /locus_tag="GAU34_RS14565"
                     /old_locus_tag="GAU34_14565"
     CDS             complement(24849..25616)
                     /locus_tag="GAU34_RS14565"
                     /old_locus_tag="GAU34_14565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_001829872.1"
                     /translation="MRTIKMVADELGVTKQTIVNNAKSLNITFEKENGINYIDDNDYLK
                     IIEKITKKESTIQNKESVKKELFGENTAKSEKNIYNNSNSSETLKTKVNELEKQIEIFE
                     TRAKNDEKYIENLTKQLDQQNSNVNTLNKLLENQQILALESNKKIQKLESQLEEERQLN
                     YSFDTATNNRQNINPQEATFTEESQNINQQQTKRQPTEVNYKDIAEEKKNDSTDEGELT
                     KEDKFVEETKNDPDDNREVEPPKKGFWSRFFGN"
                     /name="DUF536 domain-containing protein"
     gene            26056..26991
                     /locus_tag="GAU34_RS14570"
                     /old_locus_tag="GAU34_14570"
     CDS             26056..26991
                     /locus_tag="GAU34_RS14570"
                     /old_locus_tag="GAU34_14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001829877.1"
                     /translation="MPNFEKYNLSQVKTERFYQLPKYLFEDAYFKKMSAEAKIMYALLK
                     DRFELSIQNEWVDKNNNIYFIFSNKHLCEYLGYAEQKIIKLKKELISFNLLTQERVGLN
                     KPNRLYLLKPNYDIKASHSKELPNSQFQNNEFGSSRTVNLSGQELPNSQSNDTENNDTD
                     YIKTESNDTNDLNDNKLTFPSNHTNHSNHNNSNFNNEALKFQLLEELPQSIQRYLSNFS
                     VNEIKIIKPVLLKAKTSFNNSIDTYYLLEDMEIEILHVLKRFKAMLIQKNETVEAMQGY
                     LMKSLKSEFAEMHTLNKRRDHLPITSLFNQ"
                     /name="replication initiator protein A"
     ARG             22218..23758
                     /name="qacA"
                     /gene="qacA"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.81"
                     /coverage="100.0"
     ARG             19138..20573
                     /name="aac(6')-Ie/aph(2'')-Ia"
                     /gene="aac(6')-Ie/aph(2'')-Ia"
                     /gene_name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(3693..4177)
                     /name="lnuA"
                     /gene="lnuA"
                     /gene_name="lincosamide nucleotidyltransferase (LNU)"
                     /tool="rgi"
                     /drug_class="lincosamide antibiotic"
                     /identity="97.52"
                     /coverage="100.0"
     ARG             5286..6055
                     /name="ANT(4')-Ia"
                     /gene="ANT(4')-Ia"
                     /gene_name="ANT(4')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.21"
                     /coverage="101.19"
     ARG             19138..20576
                     /name="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene_name="aminoglycoside bifunctional resistance protein"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     BGC             9182..21341
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1996..2839
                     /name="rep_cluster_1281"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="86.321"
                     /coverage="91.0"
                     /evalue="0.0"
     Typing          7069..7759
                     /name="rep_cluster_1118"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="86.143"
                     /coverage="82.0"
                     /evalue="0.0"
     Typing          26057..26991
                     /name="rep_cluster_1215"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.145"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9496..10673
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="95.0"
                     /evalue="0.0"
ORIGIN
        1 cactttaaat tgtctgaata ctattgtttt tattgatttc ataggcttca gtcgtcgtca
       61 atcctataaa taggattgat ttttttatcc aaatcctatt aatcctatta cttttagtat
      121 taatatcaaa aataaaatca ctcaaaagta atctaagtaa ttcattcatt tgttttactt
      181 tttgaaattg actaaatact ttttgctcaa tatcgtattc aataatgatc ttattattta
      241 tttttaagtt caaaaaagaa gggaaagaat aaaacaattt ctatactttt ctatgctcga
      301 ttttattaaa aagtgacccg aaataaagat cactttatct ttttattaaa tagaaaatta
      361 aaaaaacgga aaaatatata ataagattca tcgaatgatt actcaaattt ttgtttgtga
      421 aatacattta tatttatttg attctcattt gcgttttaag agctaactta aaatttcaga
      481 agctcttact cactttttgg atgataaaag tgaaaataat accaaaaaat caagaaaaga
      541 tattttaatt ataacgtagc atttatgacg aaaaaattta ttgttcgttg agaagaactc
      601 ttaactaaac ttatagacga atgtcggtat agcgtgagct attaagccga ccattcgaca
      661 attttaggga gcaattgtga taaagtatta atgttttaaa cctgttacat cattgatttc
      721 gttgggatgt aacaggtttg tttcttttaa tttggatttg ttgtgagatt ataaatttat
      781 aaaaaacaag gagaagctta tgatatcgaa taaattaaaa tctgcgagat tagcaaagga
      841 attaacgcaa tctgaggtag ctaaaaaatt atacgttact agacaaactg tttctcgatg
      901 ggagcaaggt aaaacgttgc ctaatattta tgtaattcaa gaattaagcg atctttatga
      961 tatttcttta gatgaattag tagtaaatac agcattagaa aataaggagg ctaaaagtat
     1021 gaaaaatgta aatccttttg ctttatttgg agcgatatta tttaatgtgt ttttattttc
     1081 tttaatagtt atattttttg gtggcttttt gttattatct ttattcattt ctttagctat
     1141 gttatttagt cctttgattt tagcaatctt tgttttaacg ggtgtacaag agtttaatgt
     1201 aattcaacta gttatgactg ttattttcgt tgttattggt ttgttatcaa ttcctttatt
     1261 gaaaaaagtc agtgtatttt tatttaaatt tttcaaacga tatttgaaat ttaatcataa
     1321 agcaattttt tattgaattt agaaacgagt ttctttataa aagtaagcaa agatataata
     1381 taaaatgact tatcggaagt gaatatgctt atgtatttac aaatgatata ataatagagt
     1441 cgcctatctc tcaggcgtca atttgacgta gagaggaggt gcatacgcga tgtctgaaat
     1501 ctttgtgaac atcatgacca cagcagcaag tggttgtctc gttgcgctat ttgcgcattg
     1561 gctacgcaag cgtaatgacg aataggcgac tagtcacacc aaaaaatccc cttactacgg
     1621 ccatagtaag gggatttggt gcatacatgc ctgataatct ttgttaatta cattgtaaca
     1681 ctataattgg taggaatgca aagttcataa agtttgagcg taaatattat aattacggag
     1741 ttattttatt tatatctgta gtatatataa ataggaatag ggttaatgat atttataaaa
     1801 catgcatttt taattgatgt tttaaggttc tgttgcaaac ttgaaaatca tataatatag
     1861 atacaaagaa atgaaaaata ataaaatcca accgaataat ctgttgatat aatagtatat
     1921 aatttactgc ttttgcataa ctttgtatat taatttaact ttgcaacaga accaaacgac
     1981 atattgggga aaatcaaatg gatttagttg agaattgtaa tacatttttg tcttttgtga
     2041 cgaatagaag aatggacaaa aagaaattat ataaatctaa tccatgtaaa aatcgttttt
     2101 gtccgatgtg tgcatggcga aaggcgagaa aagatgcatt aggtttgtca ttgatgatgc
     2161 agcatattaa gcaagcagaa gataagcaat tcatcttttt aacacttaca acgccaaatg
     2221 taacaagtga acatttggaa agtgaaataa aacattataa tcaatcattc agacgattaa
     2281 gtaatcgtaa acattttaag tctatagcta aaggttatgt tagaaaatta gaaattactt
     2341 ataacaaaaa gcgtgatgat tataacccac attttcatgt attgattgcc gttaataaat
     2401 catattttaa agatactaaa gcttatatta ctcaaaaaga atggctagaa atgtggcgtg
     2461 atgtcacagg aaattctgaa attacacaag tacatataca aaaagttaag caaaataata
     2521 ataaagaact ttacgaaatg gctaaatatt ctggtaagga taatgactat ttaattaatc
     2581 aaaaagtgtt cgacgcattt tataaagcgt taaaaggaaa acaagttctt gtttattctg
     2641 gactgtttaa agacgcaaga aagaaattaa aaaatggaga attagattac ttaaaagaag
     2701 ttgatccgac cgaatatatt tatcaaattt tttatacttg gaataaaaaa gagtatttag
     2761 cgagtgaaat ttttgattta acagaaagtg aaaaacaaga aattaatcat caaatgattg
     2821 atgaaattga agaagaaaaa taaaaataaa ttttcttaaa cgttagcaaa aagctagcgt
     2881 ttttttgttg aaaatacgtt aaaaatggct gggtacaaac tgggtacaga cacaatatat
     2941 aggggtacaa ccggggtaca atcgcaattt gtaggggtac aatcggggta caaaataaat
     3001 ttctaggcac ctatgaaaaa tctctgtatc ccttgaaatg tctggcttcg ccagacccac
     3061 ctttttaaaa ggtggcaaat ttcccttatg ctcttaactc ttgatttggg ttcaattcaa
     3121 aatttggtat tttttgaaag aaattgcccc tgcaggaact aaaaaagttg atgaattttt
     3181 gagccatttt atgccaattt ttaatttgca tataactggg cacagtgtct aaaaaaacgg
     3241 cactggtttt gctcaaattt ttgtttgtga aattaaaata tatttatttg gctctcattt
     3301 gcgttttaag agccaatata agtttttggg tataaaacta tataaataac tctaattttt
     3361 caaaataccg ccttaaaatt aaaaataaag gtattctgat ttgtaataaa ttaaaatata
     3421 aaaaaagagc caccatttaa aatttaggca gctcttactc actttttgga tgataaaagt
     3481 ggaaaattaa ttcgagaaaa aacagaaagg atattttaat tataacacgg catttatgcc
     3541 gagaaaattt attgatgttg agaagaaccc ttaactaaac ttgtagacga atgtcggtat
     3601 agcgtgagct attaaaccga ccattcgaca agttttggga ttgttaaggg ttccgaggct
     3661 caacgtcaat aaagcaattg gaataaagca attatgttat tgattttaaa ttttttatat
     3721 caaaatggtc tttttctgtt aaatcataac cagaatgaaa aagaagttga gcttcttttg
     3781 aaatacatgg tatttttcga cctttgtaat tagtttctga aaaccagtca ttttggaaaa
     3841 cataattacc accttctggg tttgcttggg taattgatcc atcatcattt agatttatag
     3901 gatgaatatc taaataccca tattcttcat gcttaagttc catacgtgaa ggcatccaat
     3961 caacttctat tttgtatcct atatcttcta atttttgtat aactttttga gtgtgttgag
     4021 cgtcaaaatc tatatctata tctctgtgtt ctctttgttg ttttccagtt aatacatcta
     4081 ccccccagcc accatctaac caataagtta ctttcatgtg ttcaaataaa tctaaaatat
     4141 aaaataaatc tttttctgtt acattattat ttttcatttt atccctccta acttgggaat
     4201 ttgaaacaag ttgaaaacga gtttcttctt gtcttgataa taagggtaac tattacaagc
     4261 tgtgatagtt acccttattc cattgatatg actggtttta agcacaaaaa aagttgcctt
     4321 ttccagcata ctattgtatc gttttaggtg tctaagctaa acgaaaaata gaaaggagaa
     4381 aaagcaacgt cttttcgtat ttcaaacaaa gttgttttat gtgaattata tgaaaaagta
     4441 tactgagaaa aaacaaagaa atcaagtatt tcaaaacttt attaaacgac aggttctgtt
     4501 gcaaacttga aaatcatata atatagatac aaagaaatga aaaataataa aatccaaccg
     4561 aataatctgt tgatataata gtatataatt tactgctttt gcataacttt gtatattaat
     4621 ttaactttgc aacagaacca ataataaaga taattcttat aatcagcaca tgcatgtatt
     4681 ggtatgtgtg gaaccaactt attttaagaa tacagaaaac tacgtgaatc aaaaacaatg
     4741 gattcaattt tggaaaaagg caatgaaatt agactatgat ccaaatgtaa aagttcaaat
     4801 gattcgaccg aaaaataaat ataaatcgga tatacaatcg gcaattgacg aaactgcaaa
     4861 atatcctgta aaggatacgg attttatgac cgatgatgaa gaaaagaatt tgaaacgttt
     4921 gtctgatttg gaggaaggtt tacaccgtaa aaggttaatc tcctatggtg gtttgttaaa
     4981 agaaatacat aaaaaattaa accttgatga cacagaagaa ggcgatttga ttcatacaga
     5041 tgatgacgaa aaagccgatg aagatggatt ttctattatt gcaatgtgga attgggaacg
     5101 gaaaaattat tttattaaag agtagttcaa caaacgggcc agtttgttga agattagatg
     5161 ctataattgt tattaaaagg attgaaggat gcttaggaag acgagttatt aatagctgaa
     5221 taagaacggt gctctccaaa tattcttatt tagaaaagca aatctaaaat tatctgaaaa
     5281 gggaatgaga atagtgaatg gaccaataat aatgactaga gaagaaagaa tgaagattgt
     5341 tcatgaaatt aaggaacgaa tattggataa atatggggat gatgttaagg ctattggtgt
     5401 ttatggctct cttggtcgtc agactgatgg gccctattcg gatattgaga tgatgtgtgt
     5461 catgtcaaca gaggaagcag agttcagcca tgaatggaca accggtgagt ggaaggtgga
     5521 agtgaatttt gatagcgaag agattctact agattatgca tctcaggtgg aatcagattg
     5581 gccgcttaca catggtcaat ttttctctat tttgccgatt tatgattcag gtggatactt
     5641 agagaaagtg tatcaaactg ctaaatcggt agaagcccaa acgttccacg atgcgatttg
     5701 tgcccttatc gtagaagagc tgtttgaata tgcaggcaaa tggcgtaata ttcgtgtgca
     5761 aggaccgaca acatttctac catccttgac tgtacaggta gcaatggcag gtgccatgtt
     5821 gattggtctg catcatcgca tctgttatac gacgagcgct tcggtcttaa ctgaagcagt
     5881 taagcaatca gatcttcctt caggttatga ccatctgtgc cagttcgtaa tgtctggtca
     5941 actttccgac tctgagaaac ttctggaatc gctagagaat ttctggaatg ggattcagga
     6001 gtggacagaa cgacacggat atatagtgga tgtgtcaaaa cgcataccat tttgaacgat
     6061 gacctctaat aattgttaat catgttggtt acgtatttat taacttctcc tagtattagt
     6121 aattatcatg gctgtcatgg cgcattaacg gaataaaggg tgtgcttaaa tcgggccatt
     6181 ttgcgtaata agaaaaagga ttaattatga gcgaattgaa ttaataataa ggtaatagat
     6241 ttacattaga aaatgaaagg ggattttatg cgtgagaagg ttctgttgca aagttgaatt
     6301 tataatataa ttttaacaaa aaggagtctt ctgtatgaac catttcagat ataaacaatt
     6361 taacaaggat gttatcactg tagccgttgg ctactatcta agatatgcat tgagctatcg
     6421 tgatatatct gaaatattaa gagaacgtgg tgtaaacgtt catcattcaa cgatctaccg
     6481 ttgggttcaa gaatatgccc caattttata tcaaatttgg aagaaaaagc ataaaaaagc
     6541 ttattacaaa tggcgtattg atgagacgta tatcaaaata aaaggaaaat ggagctattt
     6601 atatcgtgcc attgatacag agggacatac attagatatt tggttgcgta agcaacgaga
     6661 taatcattca gcatatgcgt ttatcaaacg tctcattaaa caatttggta agcctcaaaa
     6721 ggtagttaca gatcaggcac cttcaacgaa ggcagcaatg gctaaaataa ttaaagcttt
     6781 taaacttaaa cctgactgtc attgtacatc gaaatatctg aataacctca ttgagcaaga
     6841 tcaccgtcat attaaagtaa gaaagacaag atatcaaagt atcaatacgg caaagaatac
     6901 tttaaaaggt attgaatgta tttacgctct atataaaaag aaccgtaggt ctcttcagat
     6961 ctacggattt tccccatgcc acgaaattag catcatgcta gcaagttaaa cgaacactga
     7021 catgatatat tagtgattag ctatattttt tactttgcaa cagaaccaag ctaaagcact
     7081 tcaagaaaaa gtttatattg aatatgacaa agtgaaagca gatagttggg atagacgtaa
     7141 tatgcgtatt gaatttaatc caaacaaact tacacgagat gaaatgattt ggttaaaaca
     7201 aaatataata agctacatgg aagatgacgg ttttacaaga ttagatttag cctttgattt
     7261 tgaagatgat ttgagtgact actatgcaat gtctgataaa gcagttaaga aaactatttt
     7321 ttatggtcgt aatggtaagc cagaaacaaa atattttggc gtgagagata gtaatagatt
     7381 tattagaatt tataataaaa agcaagaacg taaagataat gcagatgctg aagttatgtc
     7441 tgaacattta tggcgtgtag aaatcgaact taaaagagat atggtggatt actggaatga
     7501 ttgctttagt gatttacata tcttgcaacc agattggaaa actatccaac gcactgcgga
     7561 tagagcaata gtttttatgt tattgagtga tgaagaagaa tggggaaagc ttcacagaaa
     7621 ttctagaaca aaatataaga atttgataaa agaaatttcg ccagtcgatt taacggactt
     7681 aatgaaatcg actttaaaag cgaacgaaaa acaattgcaa aaacaaatcg atttttggca
     7741 acatgaattt aaattttgga aatagtgtac atattaatat tactgaacaa aaatgatata
     7801 tttaaactat tctaatttag gaggattttt ttatgaagtg tctatttaaa aatttgggga
     7861 atttatatga ggtgaaagaa taatttaccc ctataaactt tagtcacctc aagtaaagag
     7921 gtaaaattgt ttagtttata taaaaaattt aaaggtttgt tttatagcgt tttattttgg
     7981 ctttgtattc tttcattttt tagtgtatta aatgaaatgg ttttaaatgt ttctttacct
     8041 gatattgcaa atcattttaa tactactcct ggaattacaa actgggtaaa cactgcatat
     8101 atgttaactt tttcgatagg aacagcagta tatggaaaat tatctgatta tataaatata
     8161 aaaaaattgt taattattgg tattagtttg agctgtcttg gttcattgat tgcttttatt
     8221 ggtcacaatc acttttttat tttgattttt ggtaggttag tacaaggagt aggatctgct
     8281 gcattccctt cactgattat ggtggttgta gctagaaata ttacaagaaa aaaacaaggc
     8341 aaagcctttg gttttatagg atcaattgta gctttaggtg aagggttagg tccttcaata
     8401 gggggaataa tagcacatta tattcattgg tcttacctac ttatacttcc tatgattaca
     8461 atagtaacta taccttttct tattaaagta atggtacctg gtaaatcaac aaaaaataca
     8521 ttagatatcg taggtattgt tttaatgtct ataagtatta tatgttttat gttatttacg
     8581 acaaattata attggacttt tttaatactc ttcacaatct tttttgtgat ttttattaaa
     8641 catatttcaa gagtttctaa cccttttatt aatcctaaac tagggaaaaa cattccgttt
     8701 atgcttggtt tgttttctgg tgggctaata ttttctatag tagctggttt tatatcaatg
     8761 gtgccttata tgatgaaaac tatttatcat gtaaatgtag cgacaatagg taatagtgtt
     8821 atttttcctg gaaccatgag tgttattgtt tttggttatt ttggtggttt tttagtggat
     8881 agaaaaggat cattatttgt ttttatttta ggatcattgt ctatctctat aagtttttta
     8941 actattgcat tttttgttga gtttagtatg tggttgacta cttttatgtt tatatttgtt
     9001 atgggcggat tatcttttac taaaacagtt atatcaaaaa tagtatcaag tagtctttct
     9061 gaagaagaag ttgcttctgg aatgagtttg ctaaatttca caagtttttt atcagaggga
     9121 acaggtatag caattgtagg aggtttattg tcactacaat tgattaatcg taaactagtt
     9181 ctggaattta taaattattc ttctggagtg tatagtaata ttcttgtagc catggctatc
     9241 cttattattt tatgttgtct tttgacgatt attgtattta aacgttctga aaagcagttt
     9301 gaatagttat attatatttt ggtttagaac tatgagtggc tagcattttg ccactcattt
     9361 tttgcgttag caaaaacagg tttaagcctc gcagagcaca cgtattaacg acttattaaa
     9421 aataagtcta gtgtgttatt agacttaaac tattaaatac acatgaaacc tttgtgctta
     9481 ggagtgattt ttatatgtct tattccattg ttagagtttc aaaagttaaa tctggaacaa
     9541 atacaacggg catacaaaaa catgttcaaa gagaaaataa taattatgaa aatgaagata
     9601 tagaccatag taaaacttac ttaaattatg atttggtaaa tgctaataaa cagaatttta
     9661 ataacttgat tgatgaaaaa atcgaacaga attatacagg caaaagaaaa attagaacag
     9721 acgcgattaa acacattgat ggtttaatta catcagacaa tgatttcttt gataatcaaa
     9781 cgccagaaga tacaaagcag ttttttgaat atgctaaaga gtttttagaa caagaatacg
     9841 gtaaagataa tttattatat gcaacagttc acatggacga aaaaacacca catatgcatt
     9901 atggcgttgt tccaataact gatgatggtc gtttaagtgc taaagaagtt gtaggtaata
     9961 aaaaagcttt aacagcgttt caagatagat ttaatgagca tgttaaacaa cgaggatatg
    10021 atttagaacg tgggcaatca agacaagtaa caaatgctaa acatgagcaa ataagtcagt
    10081 ataaacaaaa aacagaatat cataagcaag aatatgaacg tgagagccaa aaaacagacc
    10141 atataaagca aaagaacgat aaattaatgc aagagtacca aaaatcgtta aatacgctta
    10201 aaaagcctat aaatgttccg tatgagcaag aaactgaaaa agtaggtggt ttatttagca
    10261 aagaaataca agaaactgga aatgttgtaa taagccaaaa agatttcaat gaatttcaga
    10321 aacagataaa agctgctcaa gatatttcgg aagattacga gtatataaag tctggtagag
    10381 ccttagatga taaagataag gaaatacgag agaaagatga tttattaaat aaagcagttg
    10441 agcgtattga aaacgcagac gataatttta accaacttta cgaaaatgca aagccactta
    10501 aagagaatat agaaatagcg ttaaagcttt taaaaatctt actaaaagag ttagaacgag
    10561 ttttaggaag aaataccttt gcggaaagag ttaataagtt aacagaagat gaaccaaaac
    10621 taaatggttt agcaggaaac ttagataaaa aaatgaatcc agaattatat tcagaacagg
    10681 aacagcaaca agaaggttct gttgcaaagt tgaatttata atataatttt aacaaaaagg
    10741 agtcttctgt atgaactatt tcagatataa acaatttaac aaggatgtta tcactgtagc
    10801 cgttggctac tatctaagat atgcattgag ctatcgtgat atatctgaaa tattaagaga
    10861 acgtggtgta aacgttcatc attcaacgat ctaccgttgg gttcaagaat atgccccaat
    10921 tttatatcaa atttggaaga aaaagcataa aaaagcttat tacaaatggc gtattgatga
    10981 gacgtatatc aaaataaaag gaaaatggag ctatttatat cgtgccattg atacagaggg
    11041 acatacatta gatatttggt tgcgtaagca acgagataat cattcagcat atgcgtttat
    11101 caaacgtctc attaaacaat ttggtaagcc tcaaaaggta gttacagatc aggcaccttc
    11161 aacgaaggca gcaatggcta aaataattaa agcttttaaa cttaaacctg actgtcattg
    11221 tacatcgaaa tatctgaata acctcattga gcaagatcac cgtcatatta aagtaagaaa
    11281 gacaagatat caaagtatca atacggcaaa gaatacttta aaaggtattg aatgtattta
    11341 cgctctatat aaaaagaacc gtaggtctct tcagatctac ggattttccc catgccacga
    11401 aattagcatc atgctagcaa gttaaacgaa cactgacatg atatattagt gattagctat
    11461 attttttact ttgcaacaga accaaaagta ttttaattat aacacggcat ttatgccgag
    11521 aaaatttatt gtgcgttgag aagaaccctt aactaaactt ggagacgaat gtcggcatag
    11581 cgtgagctat taagccgacc attcgacaag ttttgggatt gttaagggtt ccgaggctca
    11641 acgtcaataa agcaattgga ataaagcatc tatgattatt tgaaaacata agttataata
    11701 cattcaaaaa tatttttgaa tgaggtgtaa ttatgattca gactattgta actgctgcta
    11761 ttctttatat tgcgacagca gtagatttat tagtgatttt attaatattt tttgctagag
    11821 caaagactaa gaaagaatat cgagatattt atattggtca atatgtagga tctgtggcat
    11881 tgattgtcgt aagtttattc tttgcctttg tcttaaatta tgttcctgaa aaatggatat
    11941 taggattatt agggttaata ccgatttatt taggaattaa agtagctatt tatgatgatt
    12001 gtgaaggaga aaagagagct aaaaaagaat tgaatgaaaa aggattgtct aaattagttg
    12061 gtacggttgc aattgttacg atagcaagtt gtggtgctga taatattggt ttatttgttc
    12121 cgtattttgt gacattaagt gttactaatt tattaattac tctgtttgtc tttttaattt
    12181 taattttctt cttggtattt actgcacaaa aattatctaa tattccagga gttggagaaa
    12241 ttgttgagaa atttagtcgt tggattatgg ctgttattta tatagcttta ggtttattta
    12301 ttattattga aaatgatact attcaaacaa ttttaggatt tatattttaa tttagggtgc
    12361 gattttatat gagttatgaa aatgcttgtg atgtgatctg tgtacatgag gataaagtta
    12421 acaatgcttt aagtttttta gaagatgata aatctaagaa attacttaac attttagaaa
    12481 aaatttgtga tgagaagaaa ttgaaaatca tattatcttt gattaaagaa gatgagttgt
    12541 gtgtttgtga tatttctttg atattgaaaa taagtgttgc ttcaacttca catcatttaa
    12601 gacttttata taaaaatgat gtacttgatt tttataaaaa gggaaagatg gcatattatt
    12661 ttattaaaga cgatgaaata aaagaatttt tctctaaaaa tcaggagggt ttttgaaacg
    12721 agtgaaacga gtttcttctt gtcttgatac tataaaaaag caaagatata acataaaatg
    12781 acttatcgga agttatctat tatcccttat tcagagatga tataatatac aggtcgccta
    12841 tctctcaggc gtcaatttag acgcagagag gaggtgcata tcagatggtc gaagctcttg
    12901 ttcacatcac gaccacagtc atcagtggtt gtattgttgc gttatttacg cattggctac
    12961 gtacacgtaa caataagaaa aaataggcga tattagccaa cacctaaaaa tcccctcact
    13021 attgcgagta gtgaggggat tggtgcatat aatgtacgaa gctcttgttg tctaaattat
    13081 aacactggtt agtagaagaa tgcaaaacac ttatattaaa aaatgggtat ctttgagtag
    13141 tatcataagt tatagtatag aaatatttaa gtgtttgtat tcagaattta gttttccgtt
    13201 aaatgatgta ttgctagaag gtactgataa aaaagcgagt aaagaatata taaacaagaa
    13261 tcaaaaaact ttttattgtc tataatcatc tattactttc tttttactag taacttcgat
    13321 aattgcaaac agtatcattg gttattaaaa aaataaaaga tgcaaaaatg gctaaatatt
    13381 ggaaagaaaa tcaagaggga ttattaaatg atggggaagc attaactata ttaatgatgt
    13441 tatataatga gcatccatat gtagtacaat taccgtgttt aaataagcaa ctacaagatg
    13501 acaacagata cgctcaaccc acgtatacta tatattctac aaccaaaaac agaaaagaga
    13561 ataaaagaag aataaaaaat agcatataac cttaataaga taattaattt tgttatatta
    13621 aaataatata tagataattt aattatttaa agtcgaacaa ttaaaaaagt ctgggttatt
    13681 acccagactt ttttaattta aataatgagt cctattttgt agtatcagcg acagactgtt
    13741 ttaaatcatg ccaaccattt gaaatggcat taccaatact agtgacttcg ccagtgactt
    13801 caccaacaat ccctttacca ccattgatat cttttaattg tttttcattt agtgttttca
    13861 ttgaaatagt cctcctttaa attattttcc tcgtacttta ttaattgctt taccaatacc
    13921 ttgtccgata ttgcacatta ttccatcttc tacaaaatca ccagaacaac cagtttcacg
    13981 accaccattg atatctttta attgtttttc atttagtgtt tccattgaaa tagtcctcct
    14041 ttaagtaatt tcatcttaca tcttataaat tagcatttga atataaagag aatgtaaata
    14101 gacagttaag tgagcttttt tttgagttta ttttttttat tatcgaaata tatttaataa
    14161 atagagtata ttaatataaa atcagtctat tttcatttga agttgccata aatttttata
    14221 tataccgttt aaatgaatca actcatcatg tgtaccattc tcagcaattt gaccctcgtt
    14281 taaaacatag atattatcag cattttttat agtacttaat ttatgtgaaa taataattac
    14341 ggttttacca tgttgagtta gtaagtcaat atgctccata attttgtttt cagttaaact
    14401 atctaaggca cttgtagctt catcgaaaat atatatatca ggatctttta aaaatgtacg
    14461 tgctaaagat aagcgttggc cttgtccgcc cgatagatta gctccttctt tttctaacat
    14521 agtgttaaac tgatctggga atttctgtat aaaatctaag gattctgcta attgacaagc
    14581 tttaacgata tcttcatcac ttttgtattt attgctacca tgtaaaagat tgtttttaat
    14641 tgtatcagca aaaaggaatg tgttttgtga aacatagcct atattcttac gtaagtcaga
    14701 aagatcaata tcatcaataa tatagttatc aatcataata ttaccttctg aagcagtgta
    14761 atagcgattg agtaacttac ctatagttga tttaccacta ccactttcac caacaatagc
    14821 aaccttttgc ccttttttaa tatttaaatt aatatccttc aataccacac ttcgaaagcc
    14881 atactgaaag tttacatttt caatgcgaat gttgttttta aaagtataag gttgtttaga
    14941 agtatataat tcagtttcgg tctctaaatc agttatttca gcaatacgac gtgctgcaac
    15001 aaatgaagat tgcagtgttg gttgaatatt tatgagacgt tcaataggat caaggtaata
    15061 aatagttaag gcattaaaag ctaataaact acctaacgtc atactatccg tcatgactaa
    15121 gtaactacca agccacaata taacaagact gatagttaat tttaaaaagt tgttaaccgt
    15181 taattgtata ttagaaaatc tacccagttt taataagttt tcaataatac cattaaattt
    15241 agtagtacca atgtagaaac gatcgtcttc agattgataa cttttaatag tattactacc
    15301 atcaaaggat tctattaaat atgaactcaa ttcagcatct ttttcagcca ccttttgatt
    15361 atatttttca aaaggtttac gtaaagtgta actacaaata ataaaacaag gtataaaaat
    15421 aattgttatc agtagtaaca aaggactttg catataaagt aatatagcac cgataataat
    15481 catgaaagta tcaactagca acgttaccgt tgaagatgat aaagcttcac gaattttaga
    15541 tgtatccatg aaacgttgta ggatttcgcc agatttacgt gtatcaaaaa agttcatcgg
    15601 aagatgtaaa acatgataaa aataatcttt cattaaatta acatcgattt tcaaacttaa
    15661 atgtaagata agttgaaacc ttaaataatt aatgagtgca ttgattatgt ataaaagtaa
    15721 aataccgaag ctaataatat gtaaattttt aagaacattg gatggaataa tatgatcggt
    15781 taataattta aaatatagag ccccgacaat accaacaata ttaataaata gtgagataaa
    15841 agcaataaat aacaactttc cataattatt tttaaatata tcaataaaaa tattaagata
    15901 cgagggtgat tcattgtcag tagtaaaatc atctgtttta tcaattaata cagcaatatt
    15961 agtccaatat tttccaaatt cagtacttga taacttatat ttacctttag caggatcgac
    16021 aatataaagc gtgttatttt ttattttttc aataatgata tagtgatcat aaccttgttg
    16081 attaataata tgtaccataa ctggtaattg tgcttgtttt aaatcatcaa aggaatcagc
    16141 ttttacgcca gttaactcaa taccaatctt tttacctgct tgtacgagac catataaatt
    16201 tgtacctaat ttatctgttt tagcatattc gcgcaaacgt gggatagata cacgcttacc
    16261 ataaaactgt gaaatcatgg caaggcaagt aggaccacaa tccttttcat cgtattgtct
    16321 tataaatttt atagccatca taatgagtcc tttcaataaa atttaactct attttaataa
    16381 gtataaatag ttagtattaa acataagtta aataatcctt ttgataatgt taaaagcgct
    16441 aaaaagtaaa aatatttgtc tatatgtcta cttgtggtac accctaatca tacaaagaga
    16501 gttattgaat ttataataac ttaaacgtat gattagggtg tatattaatt gtggagtgaa
    16561 aatgaatgat tataggttat gcaagagtat cttcggtaga tcagaattta gagagacagc
    16621 tagataattt gaaaacattt ggcgtagaga aaatatttac agagaaacaa tcgggaaagt
    16681 cagtagaaaa tagacccgta tttcaagaag cacttaactt tgtgagaatg ggcgatagat
    16741 ttgtagtaga atcgattgat cgcttaggtc gtaattatga tgaagtgatt aacacagtta
    16801 attatttaaa ggataaagaa gttcaattga tgattactag tttacctatg atgaatgaag
    16861 tgattggtaa tccactatta gataaattta tgaaagattt aatcgttcaa atcttagcaa
    16921 tggtttcaga acaagaacga aatgaaagta aacgtagaca agcacaaggt attcaagttg
    16981 cgaaagaaaa aggtgtgtat aaaggacgcc ctttactata ttcacctaat gctaaagatc
    17041 ctcaaaaacg tattatctac catcgtgttg ttgaaatgtt agaagaaggc aaagcaatta
    17101 gtaagattgc gaaagaggtt aatatcacaa gacagacagt ttatagaatt aaaaatggta
    17161 agggattatc ttgataaatg gattgttaat gcaaatgaga tcttctcaca gcgtcctaaa
    17221 ttatatgtta ttcatctatt atgagattct aataataaga caagaaaaga gagtgcgaat
    17281 tcgcactctc cttttgtgta gtactattga aattttgtct taaaaacgaa cgtaatttag
    17341 aaataatatt tattggtatt tcaagaaggt tctgttgcaa agtaaaaaat atagctaacc
    17401 actaatttat catgtcagtg ttcgcttaac ttgctagcat gatgctaatt tcgtggcatg
    17461 gcgaaaatcc gtagatctga agagacctgc ggttcttttt atatagagcg taaatacatt
    17521 caataccttt taaagtattc tttgctgtat tgatactttg ataccttgtc tttcttactt
    17581 taatatgacg gtgatcttgc tcaatgaggt tattcagata tttcgatgta caatgacagt
    17641 caggtttaag tttaaaagct ttaattactt tagccattgc taccttcgtt gaaggtgact
    17701 gatctgtaat taccttttga ggtttaccaa attgtttaat gagacgtttg ataaacgcat
    17761 atgctgaatg attatctcgt tgcttacgca accaaatatc taatgtatgt ccctctgcat
    17821 caatggcacg atataaatag ctccattttc cttttatttt gatgtacgtc tcatcaatac
    17881 gccatttgta ataagctttt ttatgctttt tcttccaaat tcgatataaa attggggcat
    17941 attcttgaac ccaacggtag accgttgaat gatgaacgtt tacaccacgt tcccttaata
    18001 tttcagatat atcacgataa ctcaatgcat atcttagata gtagccaacg gctacagtga
    18061 taacatcctt gttaaattgt ttatatctga aatagttcat acagaagact cctttttgtt
    18121 aaaattatac tataaattca actttgcaac agaaccattt tttgaatacc taaaagaacg
    18181 cggtttacaa ggtacggaac tcgttatttc tgatgcgcac aaaggattag tctctgccat
    18241 tagaaaatcc ttcaccaacg taagttggca aagatgccaa gttcacttcc taagaaatat
    18301 ctttaccacc attcctaaaa aaattcaaaa tctttcagag aagctgttaa aggaattttt
    18361 aagttcacag atattaactt agcgcgtgag gctaaaaatc gattgattca tgattatatc
    18421 gatcaaccaa aatattcaaa agcttgcgca tcattggatg atggattcga agacgccttt
    18481 caatataccg tacaaggaaa ttcccacaat cgactaaaga gtaccaatct aattgaacga
    18541 ctgaatcaag aagtacgcag aagagaaaag attattcgca tcttccccaa tcaaacatca
    18601 gccaatcgct taattggagc cgttcttatg gacctacatg atgaatggat ttattcttca
    18661 agaaaataca tcaattttga taagtagaaa tggtaaaaac attgtatagc attttacaca
    18721 ggagtctgga cttgactgag tttatggaag aagttttaat tgatgataat atggtttttg
    18781 atattgataa tttaaaagga tttcttaatg ataccagttc atttgggttt atagctaaag
    18841 aaaataataa aattatagga tttgcatatt gctatacact tttaagacct gatggaaaaa
    18901 caatgtttta tttacactca ataggaatgt tacctaacta tcaagacaaa ggttatggtt
    18961 caaaattatt atcttttatt aaggaatatt ctaaagagat tggttgttct gaaatgtttt
    19021 taataactga taaaggtaat cctagagctt gccatgtata tgaaaaatta ggtggtaaaa
    19081 atgattataa agatgaaata gtatatgtat atgattatga aaaaggtgat aaataaatga
    19141 atatagttga aaatgaaata tgtataagaa ctttaataga tgatgatttt cctttgatgt
    19201 taaaatggtt aactgatgaa agagtattag aattttatgg tggtagagat aaaaaatata
    19261 cattagaatc attaaaaaaa cattatacag agccttggga agatgaagtt tttagagtaa
    19321 ttattgaata taacaatgtt cctattggat atggacaaat atataaaatg tatgatgagt
    19381 tatatactga ttatcattat ccaaaaactg atgagatagt ctatggtatg gatcaattta
    19441 taggagagcc aaattattgg agtaaaggaa ttggtacaag atatattaaa ttgatttttg
    19501 aatttttgaa aaaagaaaga aatgctaatg cagttatttt agaccctcat aaaaataatc
    19561 caagagcaat aagggcatac caaaaatctg gttttagaat tattgaagat ttgccagaac
    19621 atgaattaca cgagggcaaa aaagaagatt gttatttaat ggaatataga tatgatgata
    19681 atgccacaaa tgttaaggca atgaaatatt taattgagca ttactttgat aatttcaaag
    19741 tagatagtat tgaaataatc ggtagtggtt atgatagtgt ggcatattta gttaataatg
    19801 aatacatttt taaaacaaaa tttagtacta ataagaaaaa aggttatgca aaagaaaaag
    19861 caatatataa ttttttaaat acaaatttag aaactaatgt aaaaattcct aatattgaat
    19921 attcgtatat tagtgatgaa ttatctatac taggttataa agaaattaaa ggaacttttt
    19981 taacaccaga aatttattct actatgtcag aagaagaaca aaatttgtta aaacgagata
    20041 ttgccagttt tttaagacaa atgcacggtt tagattatac agatattagt gaatgtacta
    20101 ttgataataa acaaaatgta ttagaagagt atatattgtt gcgtgaaact atttataatg
    20161 atttaactga tatagaaaaa gattatatag aaagttttat ggaaagacta aatgcaacaa
    20221 cagtttttga gggtaaaaag tgtttatgcc ataatgattt tagttgtaat catctattgt
    20281 tagatggcaa taatagatta actggaataa ttgattttgg agattctgga attatagatg
    20341 aatattgtga ttttatatac ttacttgaag atagtgaaga agaaatagga acaaattttg
    20401 gagaagatat attaagaatg tatggaaata tagatattga gaaagcaaaa gaatatcaag
    20461 atatagttga agaatattat cctattgaaa ctattgttta tggaattaaa aatattaaac
    20521 aggaatttat cgaaaatggt agaaaagaaa tttataaaag gacttataaa gattgattat
    20581 ataatatatg aaaagctatt ataaaagaca ttagtattaa atagtttaaa aaaatgaaaa
    20641 ataataaagg aagtgagtca agtccagact cctgtgtaaa atgcggttct gttgcaaagt
    20701 aaaaatatag ctaaccacta atttatcatg tcagtgttcg cttaacttgc tagcatgatg
    20761 ctaatttcgt ggcatggcga aaatccgtag atctgaagag acctgcggtt ctttttatat
    20821 agagcgtaaa tacattcaat accttttaaa gtattctttg ctgtattgat actttgatac
    20881 cttgtctttc ttactttaat atgacggtga tcttgctcaa tgaggttatt cagatatttc
    20941 gatgtacaat gacagtcagg tttaagttta aaagctttaa ttactttagc cattgctacc
    21001 ttcgttgaag gtgactgatc tgtaattacc ttttgaggtt taccaaattg tttaatgaga
    21061 cgtttgataa acgcatatgc tgaatgatta tctcgttgct tacgcaacca aatatctaat
    21121 gtatgtccct ctgcatcaat ggcacgatat aaatagctcc attttccttt tattttgatg
    21181 tacgtctcat caatacgcca tttgtaataa gcttttttat gctttttctt ccaaattcga
    21241 tataaaattg gggcatattc ttgaacccaa cggtagaccg ttgaatgatg aacgtttaca
    21301 ccacgttccc ttaatatttc agatatatca cgataactca atgcatatct tagatagtag
    21361 ccaacggcta cagtgataac atccttgtta aattgtttat atctgaaata gttcatacag
    21421 aagactcctt tttgttaaaa ttatactata aattcaactt tgcaacagaa ccttatttac
    21481 taagtccatt taaaaaaatt tgagagaact tgttcataag tttaattctt tcattaatat
    21541 tttgttcatg tgtaaaggta acaattccat taacagcgtt tgctgctatt ttactaacag
    21601 cattaacatc attaatacac cattcgccat ttaaattacc ctccttaaaa attacatgat
    21661 aagcatctat atatttgttt tctaatttat tcattttttc attaatgcta ttagttttat
    21721 aatattcagt gcaaaattca attattgcgt tttgaagtgg ataatagtat tcggttgtta
    21781 aagatagttc attatataaa taaaattttt ctctattagt tttacatttg atttgttcct
    21841 ttttccactg ttcttgccat ttagattctt ctatatttaa aatttctaaa aatagatttt
    21901 cttttgtttt aaagtgataa taaagattcc ctttactact ttctgataat ttaacaattt
    21961 ctccagtagt agtggcatta tatccatttt ttataaataa ttcctttgcg acacctagta
    22021 ttttatcttt caagttcatc acgcctttaa tgagtattaa gtactatcaa tgatagcaca
    22081 aaaaattcaa agaataattg tataacacaa tacagccatt taaatttcgc aagatttttt
    22141 gttgtaatat gtaaaaaaat agattacaat ccttatagac cgatcgcacg gtctataagg
    22201 attggaggga acttaaatga tttcattttt tacaaaaact actgatatga tgacatcaaa
    22261 aaaaagatgg actgcactag taatattagc tgttagtttg tttgttgtta caatggatat
    22321 gacaatatta attatggctt taccggaatt agtaagagag ttagagcctt ctggtaccca
    22381 acagttatgg atagttgata tatactctct tgttttagct ggctttataa ttccattgag
    22441 tgcctttgct gataaatggg gaagaaaaaa agcattatta actggatttg ctttatttgg
    22501 cctcgtttca ttagctatat ttttcgcaga aagtgcagag ttcgtaatag ctattcgatt
    22561 tttacttggt attgcaggtg ctttaataat gccaactact ctttcaatga taagagtaat
    22621 ttttgaaaac cctaaagaaa gggccactgc attagctgta tggtcaatcg cttcatcgat
    22681 aggtgctgtt tttggaccaa ttatcggagg agctttactt gagcaatttt catggcactc
    22741 ggcattttta attaatgtac cgtttgcgat aatagcagtt gtagcaggtt tatttttatt
    22801 accagagtct aagttatcaa aagaaaagtc tcactcgtgg gatattcctt ctacaatttt
    22861 atcaattgca ggcatgattg gactggtatg gagtatcaaa gaattttcaa aagaaggact
    22921 agcagatatt attccatggg ttgtaatagt attagcaatt accatgatag tgatatttgt
    22981 taaacgtaat ttatcaagtt ctgatccaat gttagacgta agacttttta aaaagagatc
    23041 attttcagct ggtacaattg ctgcatttat gacaatgttt gcaatggcat ctgttttgtt
    23101 attagcttca caatggttac aggttgtgga agaactttct ccttttaaag ctggcttata
    23161 cctattacct atggcaatag gagatatggt gtttgcacca attgcacccg gattagcggc
    23221 gcgatttgga ccgaaaatag tgttaccttc cggaattgga attgcagcca ttggcatgtt
    23281 tattatgtat ttctttggtc atccattatc atattctaca atggctttag cattaatttt
    23341 agttggagct ggtatggctt cactagcagt tgcatctgct ctaataatgt tagaaacacc
    23401 tacatcaaaa gcaggtaatg cagctgctgt tgaagagtct atgtatgacc ttggaaatgt
    23461 ttttggtgta gcagtacttg gtagcctatc ttctatgctt tatcgtgtat ttttagatat
    23521 ttcatctttt tcatcaaaag gtatagttgg agatttagct catgtagctg aagaatctgt
    23581 agtgggcgct gtcgaagtag ctaaagctac ggggataaaa cagcttgcaa acgaggctgt
    23641 aacatcattt aatgatgctt ttgtagcaac tgctttagta ggtgggatta tcatgattat
    23701 catttcaata gttgtctatt tgttaattcc caaatcactt gatataacta aacaaaaata
    23761 gtactaaaca tatattttta gatattgtag attagtttat ttttaaaatt agtaatagtt
    23821 aaaaagtaga accattaatt ttaaatggtt ctactttttt attattaagt aaaattataa
    23881 aagacaattt cttaaattaa taatatgata tacctatatc taataattta ttagtattaa
    23941 taaaccttga aaggatgatt aactgatgaa tagagcagat atttttaaaa tatttgatgt
    24001 agaacttaat ataactatat ttttaggagc actagtagca actttcatct attttataag
    24061 ttacatgaac aatgtaaatg aattaattac attatgctta acattagctt ttcctgcata
    24121 tttattaaaa attagcagat cgttcgaggt tattttatta gaggaaaaaa taaaaaatag
    24181 taaaatcaaa atctgtgaca aagatagaat tgaacgagag atactggtga aaaagaacct
    24241 aatagatgaa ctattgtttc ctaatagagt tattaaaaaa tatacactga caattttaat
    24301 ttacagtata ggtattatta ttcttttact actttgtaat atgttaagtt atggaattgg
    24361 tgaaaatgtc aattttatct ggagattact agcttgttat gtaacgagtg tcacagtgat
    24421 tatagttgcc ttgattataa tgataatgat atttgatctt ataattggat tactattaaa
    24481 ttttcaaata tttttaaaaa ataaaaagta tgatgacttt ttataattat tcgatttata
    24541 taatgaaaaa ttaaatgatt aaacatagaa acctcaaaac aaaccatatt taatagagtt
    24601 tatggcgcct tatacaaata aaggctatgc tgttaaagaa ttatgtagct atcttcagat
    24661 taatatggat gatgtttata ctattggcga tagaaaattg atttacctat gtttaatacc
    24721 ctagataatt cttctgataa tttagttttt gttagagttt aacataactg atgattatca
    24781 gaagtttcat cactataaaa ggtgtatcaa agatttatac tcccttgata caccttttac
    24841 attcattttt aattaccgaa gaatcgactc caaaatccct ttttaggtgg ttctacctcc
    24901 ctattatcat caggatcatt cttcgtttct tcaacgaact tatcctcttt tgttaattca
    24961 ccttcatctg tactgtcatt ctttttctct tcggctatat ccttgtaatt tacttctgtt
    25021 ggttgacgct ttgtttgttg ttggttgata ttttgcgatt cttcagtaaa agttgcttct
    25081 tgcggattaa tattttgtct attattcgtc gctgtatcaa aagaataatt aagctgtctt
    25141 tcttcttcta attgactttc tagtttttga atttttttat tgctttctaa agctaatatt
    25201 tgttgattct ccaacaattt atttaacgta ttaacattgc tattttgttg atctaattgc
    25261 ttagttaaat tctcaatata tttttcatca tttttagctc tagtttcaaa gatttctatt
    25321 tgcttttcta attcgtttac ttttgttttt aatgtctcag aactatttga attattatat
    25381 atattctttt ctgattttgc agtattttca ccaaacaatt ctttttttac tgattcttta
    25441 ttttggattg tactctcttt cttagtaatt ttttctataa ttttcaaata atcattatca
    25501 tcaatataat taatcccatt ttctttttca aaagttatat ttaaactttt agcattatta
    25561 acaatagttt gtttagttac acctaattca tcagcaacca ttttaatagt tctcataaca
    25621 tccaccctta ggtacctaat ttagtaccta aattttacca cctaatgaat tttatttcat
    25681 caattaccac taaatttact acctatttac tacatatgca cctaattagc tacctataat
    25741 atgtttttgg agcttaatta ggtactaaaa caatgaacta cacattttgc catggcaatg
    25801 tgcttttaac tacatttaaa actctttata tactttctta aaagtgttaa tattgcttta
    25861 taaatactaa aagagtcaat gctattggcg tagcattgac tctcggtaat aaaacgattc
    25921 gcactcgttt gtttatatat tttttgatac ttgtattata tctatctaat catctaagtg
    25981 caagcacaaa acatataact tacgtaaaaa ttgttttatt acctcaatcc taaaaatgga
    26041 aatgaggttt ttattatgcc caattttgaa aaatacaatt tatcacaagt aaaaactgaa
    26101 aggttttatc aactacctaa atatttattc gaagatgcat attttaaaaa aatgtcggcg
    26161 gaagccaaaa ttatgtatgc gttattaaaa gatcgctttg aattatccat ccaaaatgaa
    26221 tgggtagata aaaataataa catttacttt attttcagta ataaacattt gtgcgaatac
    26281 ttaggttatg cagaacaaaa aattataaaa ttaaaaaaag agttaataag ttttaattta
    26341 ttaactcaag aacgtgttgg ccttaataaa ccaaatagat tatatttatt aaaacctaat
    26401 tatgacatta aagccagtca tagcaaggaa cttccaaatt cacagttcca gaacaatgaa
    26461 tttggaagtt ctagaactgt gaatttaagt ggtcaagaac ttccaaattc acagtctaat
    26521 gatactgaga ataatgatac tgattatatt aaaactgaga gtaatgatac gaatgatttg
    26581 aatgataata agctaacttt tcctagtaat catacaaatc attcaaatca caacaattca
    26641 aactttaata atgaagcttt aaaattccaa ttactcgaag aactacctca aagtattcaa
    26701 aggtatttaa gtaacttttc tgtaaatgaa attaaaatca tcaaacctgt attattaaaa
    26761 gccaagacgt cctttaataa ttctattgat acatattact tattagaaga tatggaaata
    26821 gaaatacttc atgttcttaa acgtttcaaa gctatgctta ttcaaaaaaa tgaaaccgtt
    26881 gaagccatgc aagggtactt aatgaaatcc cttaagtctg aattcgctga aatgcatacg
    26941 cttaataaac gacgtgatca tttaccaatc acttctttat ttaatcaata atgattcaat
    27001 tagagagcat ctttaaatag atgttctctt tttttattta caagtggttg ctaaggcaac
    27061 cacctagatc aaacgaaagg taagggaggg gataacaaaa taagatcaac acaatatcac
    27121 aatatagcat gctgctatta aagaaaggag gaagaattat gagtactaag aaaaagatta
    27181 aagttacttt ggcaatgatt aatgttcttt taactgcagt cgaactttat cttcaatggc
    27241 aattgagtaa atctgaaaat gaactgtagt taaacaagta ggtaggacta aaacgtttct
    27301 gttttagtcc tattttttct ataaatggtt attattcatt tgaaaatggc tcaaacatgt
    27361 cgcataagat gaaaaataaa atgatcattt aacgttgttt taactttaaa aattataaaa
    27421 atactaaccg tttttatatt ctttagcaat ctttcttagt tataaaagta acttaataaa
    27481 atcgtttttg tcatttactt tgttaatgat cggaaagaaa agattgattt tatcattcca
    27541 aaaaatcaaa attcagattc aattgatata catcataaac aaaaagtaag tcgttaatgt
    27601 tcaagacata agtcgaatgt aattttaaat ttgatttttt ctatcccaaa ctgagtaaag
    27661 atatttactt agttttcttt tttttttatc tccaattatt ttactaacaa tgcttatttt
    27721 gaaaataaaa ataagcactt aaagtaaaaa gtgaacaaga gaatagccac ttttgtctta
    27781 aagcacgttt tgtttttgga aatattacaa atataatagg attttcaaat agtatttgac
    27841 atgagcataa ggaaatccag taccaccttt ggtggtattc agcatagctg aaggattgtc
    27901 ttaccgttcg ctttgcttac ttgctctttg aaattcacta caagtgttga tataacaaca
    27961 tttatagtta atattaaata aaaattaatc gacattataa accttaatat tgcatactat
    28021 ttacaattgt tacaagacac
//
