LOCUS       NZ_CP047857            34909 bp    DNA     circular CON 18-DEC-2023
DEFINITION  Staphylococcus aureus strain UP_1435 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP047857
VERSION     NZ_CP047857.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN11175594
            Assembly: GCF_009912895.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 34909)
  AUTHORS   Dilthey,A., Meyer,S. and Kaasch,A.
  TITLE     Increasing the efficiency of long-read sequencing for hybrid
            assembly with k-mer-based multiplexing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 34909)
  AUTHORS   Dilthey,A., Meyer,S. and Kaasch,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JAN-2020) Institute for Medical Microbiology and
            Hospital Hygene, University Hospital Duesseldorf, Moorenstrasse 5,
            Duesseldorf 40225, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Unicycler Hybrid Assembly v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 227x / 184x
            Sequencing Technology :: Illumina MiSeq / Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/17/2023 03:58:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,866
            Genes (coding)                    :: 2,781
            CDSs (with protein)               :: 2,781
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 85
            CDSs (without protein)            :: 85
            Pseudo Genes (ambiguous residues) :: 0 of 85
            Pseudo Genes (frameshifted)       :: 51 of 85
            Pseudo Genes (incomplete)         :: 40 of 85
            Pseudo Genes (internal stop)      :: 27 of 85
            Pseudo Genes (multiple problems)  :: 31 of 85
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047857.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..34909
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="UP_1435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
     gene            complement(566..931)
                     /locus_tag="E3S66_RS14385"
                     /old_locus_tag="E3S66_14385"
     CDS             complement(566..931)
                     /locus_tag="E3S66_RS14385"
                     /old_locus_tag="E3S66_14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001632001.1"
                     /translation="MDKNKLEIYLKICENIKEYKNLEFECYNEDEEVFDSNLQCPLAYT
                     TKGDNEEFEIQVTLDLNNNQIIKEISHVYINYKEYECFKDWEEIASKTLNFDDLIMTDM
                     DVDDLLEEIPNKKGIKY"
                     /name="hypothetical protein"
     gene            complement(1191..1745)
                     /locus_tag="E3S66_RS14390"
                     /old_locus_tag="E3S66_14390"
     CDS             complement(1191..1745)
                     /locus_tag="E3S66_RS14390"
                     /old_locus_tag="E3S66_14390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001062593.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001062593.1"
                     /translation="MAKIGYARVSTKDQSLDGQIDTLKEFGCERIFSEKISGRKVKRTE
                     LDKCLDYLREGDTLVIYKLDRLGRTTKQLIELSQWLDDNGIDLQIIDMNVSTKDAMGKM
                     FFTMMSAFAELEANLLSERTKKGLAAARARGRLGGRPSLPDHKKREIKFLYDEQMMTGE
                     EIAKKTGVSRSTVYRIVKERK"
                     /name="recombinase family protein"
     gene            complement(2671..3387)
                     /locus_tag="E3S66_RS14395"
                     /old_locus_tag="E3S66_14395"
     CDS             complement(2671..3387)
                     /locus_tag="E3S66_RS14395"
                     /old_locus_tag="E3S66_14395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_031899109.1"
                     /translation="MSQINLNEVIKNVEMLLRSPITLKEISECTGISENVLKKLSSGER
                     EVTNAKFEVINLLYQFYLENKSEIFKDKSFMEELSSVNLPKNIRNFIKDLSNAIDQVNN
                     NEQEMLYEVKTIYVKDKQGHIEEKGKCIAVDENLALNLDVNTGFAKDPYDLKINTEISD
                     IVDELKHVKIIFDELGLENALKQIKYDGGKIKLSKEKRHIMVYPKGTSLYEYNRFDYIG
                     AFERMFFSLEYNQEKN"
                     /name="hypothetical protein"
     gene            3559..3975
                     /locus_tag="E3S66_RS14400"
                     /old_locus_tag="E3S66_14400"
     CDS             3559..3975
                     /locus_tag="E3S66_RS14400"
                     /old_locus_tag="E3S66_14400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YolD-like family protein"
                     /protein_id="WP_160176693.1"
                     /translation="MYVINPELPEPYKYETDYRKIPKELLNSNIPKGRDKVKWAPFKTV
                     SDQYKLLDEYIEEQNKIEMPLLSDDQLQILNETVYYNSMNNILTELSYWDNGYINSMEC
                     YINKVDALEHVMIVSNESKETKIKIPLNSIININ"
                     /name="YolD-like family protein"
     gene            complement(4014..4238)
                     /locus_tag="E3S66_RS14405"
                     /old_locus_tag="E3S66_14405"
     CDS             complement(4014..4238)
                     /locus_tag="E3S66_RS14405"
                     /old_locus_tag="E3S66_14405"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001285191.1"
                     /translation="MSDSNKNLPENVIKFDSIIKVKNDKVECQCGDKAKYRISERYKLV
                     TCEICGKNVDPFTALLVIVKRLKNFYHNN"
                     /name="hypothetical protein"
     gene            complement(4257..4706)
                     /locus_tag="E3S66_RS14410"
                     /old_locus_tag="E3S66_14410"
     CDS             complement(4257..4706)
                     /locus_tag="E3S66_RS14410"
                     /old_locus_tag="E3S66_14410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632017.1"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="WP_000725509.1"
                     /translation="MKKIYIENIDDYIIVDDEDFERVNFYKWHKSYAHDTQRFLAQILG
                     KKTALPVFILNNQYAYQKVKNNDFTRRNLGADKHSFRYRAPQKNSSSKYKGVSYDSKHN
                     KWVASIYAEGEKKYLGRFVDEKECAKAYNNAVLKYWDGDGYLNDV"
                     /name="AP2 domain-containing protein"
     gene            complement(4972..5121)
                     /locus_tag="E3S66_RS14745"
     CDS             complement(4972..5121)
                     /locus_tag="E3S66_RS14745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001031498.1"
                     /translation="MNKETLIDLIDMMIGLTEIERKRLSEMEMRKVEIRYKMALTEKTD
                     EMIG"
                     /name="hypothetical protein"
     gene            complement(5248..6198)
                     /locus_tag="E3S66_RS14415"
                     /old_locus_tag="E3S66_14415"
     CDS             complement(5248..6198)
                     /locus_tag="E3S66_RS14415"
                     /old_locus_tag="E3S66_14415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="WP_001035523.1"
                     /translation="MNKKLIASGTIASILLLNTGGVAFADSNKLNEDIFIKGADLNSQQ
                     LEETKKKLEVDDGYKEISITTNDVAKYTGNNNLSFIHSSATITPKKFKKGVTVDIETPE
                     NITRITKEQYTNAAITAGIQDSEIKVASIDKVTGEGALTGIYKAYEENGNSLNKDDVQN
                     ANKEMNDLASISEQNKGQKGYSDEALNNAIAEMKKEIASEKQDGKNLTREDISKIVNDI
                     LKENGLNKILSDNQINVINNIMVNVSNSEILNKDPKAYEKQAKDLASNIKDKAGNLLDK
                     AKELNTEENRNFLQKIWDSIVEFFKKIINWLLSWF"
                     /name="DUF1002 domain-containing protein"
     gene            complement(6262..6474)
                     /locus_tag="E3S66_RS14420"
                     /old_locus_tag="E3S66_14420"
     CDS             complement(6262..6474)
                     /locus_tag="E3S66_RS14420"
                     /old_locus_tag="E3S66_14420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001003548.1"
                     /translation="MNEKVKKYESPSHKHRRTVQLYKNVDDIANELKFDLKLNSKQEVY
                     TKAIELLYKQIRGEEINLSQNKTNK"
                     /name="hypothetical protein"
     gene            complement(6549..6845)
                     /locus_tag="E3S66_RS14425"
                     /old_locus_tag="E3S66_14425"
     CDS             complement(6549..6845)
                     /locus_tag="E3S66_RS14425"
                     /old_locus_tag="E3S66_14425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000988039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000988039.1"
                     /translation="MMTAYIAKQNDGTILSKDIDVSLVIQDVIEQRIENFERYYNHYKE
                     NLEINYYIYIGNLNKLYNNIEDYTNELSLIDDFYKTYNNEDYVDSSQIVRIET"
                     /name="hypothetical protein"
     gene            complement(6953..7165)
                     /locus_tag="E3S66_RS14430"
                     /old_locus_tag="E3S66_14430"
     CDS             complement(6953..7165)
                     /locus_tag="E3S66_RS14430"
                     /old_locus_tag="E3S66_14430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000428931.1"
                     /translation="MENKTHYFEAHGKDYKLEVAKDMFGCEGVTVIENGLYMGMIDCAD
                     ERDYKRIESMIRADKHFVYTDEVYC"
                     /name="hypothetical protein"
     gene            complement(7331..7573)
                     /locus_tag="E3S66_RS14435"
                     /old_locus_tag="E3S66_14435"
     CDS             complement(7331..7573)
                     /locus_tag="E3S66_RS14435"
                     /old_locus_tag="E3S66_14435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="WP_000885246.1"
                     /translation="MAFNKRENNKGKDINTALEEAKSPEFNARSFGILKRNNKEKKERF
                     QFTLEPSVRKKIERLANENGYASSSEFINELIKNI"
                     /name="ribbon-helix-helix domain-containing protein"
     gene            complement(7742..8548)
                     /locus_tag="E3S66_RS14440"
                     /old_locus_tag="E3S66_14440"
     CDS             complement(7742..8548)
                     /locus_tag="E3S66_RS14440"
                     /old_locus_tag="E3S66_14440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402875.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000402876.1"
                     /translation="MEIITFAAIKGGVGKTTLSYNFSEYLASVGKKVLLIDMDHQCNLS
                     QLLNVYEQENTVLSIFNKIDGLNINEEVKVHKVKTNIDLISGFLRLDEYERVMSTVDGK
                     DMQLYMWLDDNYDKYNIEKYDYIIIDTHPDFSTSTRNAIAVSHKVISPNKPSGFSDDSN
                     SNIEYRIDKLKNDLIDFRTRESYVTAKLYYVGNMVKHNTKSSNHFIEEMNSNNKYITYF
                     PDKELITKSVMEKKPIVDFSKDKNILSKNRTFFKDFVKSCEVIKKM"
                     /name="ParA family protein"
     gene            9040..10035
                     /locus_tag="E3S66_RS14445"
                     /old_locus_tag="E3S66_14445"
     CDS             9040..10035
                     /locus_tag="E3S66_RS14445"
                     /old_locus_tag="E3S66_14445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_160176694.1"
                     /translation="MSEQRFNIQQQYREKFYQLPKVFFTNEKYMQLSNDAKIAYALLKD
                     RLELSIKNNWFDENGDIFFIFTNDKLKNILNCHDGKLTKIKKELSKADLLEQVRCGQGK
                     PNKLYLKNPAITKEDVYEIKKQEETSGEPSHDAEMRKSHFKKCENRISRNAKIAQQEMR
                     KSHTNDTDLSNTYYIETENNDMNDLNDVESKNEISNHSNHSNQFTHNFDDKDYKEILLQ
                     EFPEQLTNYLLKYDYRDLEIIKAVILKAKKSFNSNHDDNFYMLEHIENEILISLKRLKK
                     AIHDRRVKGQKETIKSMQGYLMQTILTELEELHSTDMRRKNLKNSSWNIF"
                     /name="replication initiator protein A"
     gene            10093..10389
                     /locus_tag="E3S66_RS14450"
                     /old_locus_tag="E3S66_14450"
     CDS             10093..10389
                     /locus_tag="E3S66_RS14450"
                     /old_locus_tag="E3S66_14450"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001244817.1"
                     /translation="MRNKNYIGGLTKENLKGFVILVLIFLYVLSALLNLTGFFWGYVFM
                     PVFAIWSIYMMFFRGYFIPVVKILFIITLTTIKFVFMVFFIMAIASSLSDKKY"
                     /name="hypothetical protein"
     gene            complement(10483..10803)
                     /locus_tag="E3S66_RS14455"
                     /old_locus_tag="E3S66_14455"
     CDS             complement(10483..10803)
                     /locus_tag="E3S66_RS14455"
                     /old_locus_tag="E3S66_14455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001175018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001175018.1"
                     /translation="MQKYPRVFRIKSTTKQLIKITSAINDLNNSDFVEKIIQETELSNI
                     DFSSYNNYGKKSYNTVQATYTISYSSNEKIEAVAQKHGLTRSQVLNLFLSKYLNIPIDH
                     KD"
                     /name="hypothetical protein"
     gene            11227..11517
                     /locus_tag="E3S66_RS14460"
                     /old_locus_tag="E3S66_14460"
     CDS             11227..11517
                     /locus_tag="E3S66_RS14460"
                     /old_locus_tag="E3S66_14460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000882874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000882874.1"
                     /translation="MLCYKKNKRFDFIAFYFFADEIRTFDGKTYRIKGMRCQRIDHKRL
                     DINERKTLRHLSEVIYKTKTVFNDNYGLIAYRKKVSQELKSVKNISISKSV"
                     /name="hypothetical protein"
     gene            11779..11973
                     /locus_tag="E3S66_RS14465"
                     /old_locus_tag="E3S66_14465"
     CDS             11779..11973
                     /locus_tag="E3S66_RS14465"
                     /old_locus_tag="E3S66_14465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000036647.1"
                     /translation="MSKITQNDLNQLKKQVTEIMKVTGETHNEWLYNQYQNYLSENTDV
                     VMEALRFYSENKNNTAWEE"
                     /name="hypothetical protein"
     gene            11977..12273
                     /locus_tag="E3S66_RS14470"
                     /old_locus_tag="E3S66_14470"
     CDS             11977..12273
                     /locus_tag="E3S66_RS14470"
                     /old_locus_tag="E3S66_14470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000481731.1"
                     /translation="MFNGLNEKIVALINDAQPLIITLLALSIFVSGAVMMFGDTGVRWA
                     KRTLIGAIIGAVLSGGALVYARSFKKIVNVSAVFPSATETKFAVIDTLQIIFM"
                     /name="hypothetical protein"
     gene            12326..13468
                     /locus_tag="E3S66_RS14475"
                     /old_locus_tag="E3S66_14475"
     CDS             12326..13468
                     /locus_tag="E3S66_RS14475"
                     /old_locus_tag="E3S66_14475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000944343.1"
                     /translation="MLRIKTKSFHIKNQSDFSLEEMMSYTEDMEAGKFPESLDKFDYVM
                     YDEQTYEDILESTYKVNSGYINIQQQIYTLLKATAPDTEELKRLKRQYLIALQEVGKSY
                     RDKKVAMNKKKNNPDNTKFQYQRQNNANKTKQKEILEKLKGKRGLMFLGLIVFVMLLVY
                     ILVVTDPNKKGASDVATKEEIYQQALLGEEEKAIDNFAKLDQETLTKKDKQIYAQLLAQ
                     KEEYDKAVKLSDAKFVEAYLISRDYYSALEEFNKKYPTNNGKFDLAIHQNKFSDAINYS
                     QGIDKTNNRKKQLVKAYIETDNLNKAKELAATTEDKEVTKMIADEQNKRLKGLEEAVKS
                     KEDDLKKAKDKKEKKSDIENKEKALKEANENLEKFKKELK"
                     /name="hypothetical protein"
     gene            13483..13926
                     /locus_tag="E3S66_RS14480"
                     /old_locus_tag="E3S66_14480"
     CDS             13483..13926
                     /locus_tag="E3S66_RS14480"
                     /old_locus_tag="E3S66_14480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000931137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000931137.1"
                     /translation="MLNEFKFIGRIARDLELTTKENMQARCNFTLAVNNAYGTDFLNIT
                     AFDKTAENLVKYNQKGDMVYVEGYVSTNKKSVNGVDKYYMNLVAGRIVYLSNKKVEESE
                     NELEHSTDNLDNLTFDDKQHTEVNENNTTFQKAKGFVTEDLPF"
                     /name="single-stranded DNA-binding protein"
     gene            13941..16712
                     /locus_tag="E3S66_RS14485"
                     /old_locus_tag="E3S66_14485"
     CDS             13941..16712
                     /locus_tag="E3S66_RS14485"
                     /old_locus_tag="E3S66_14485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001210915.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="WP_001210915.1"
                     /translation="MRFGSKDKHGYRRKKLSFSQNKHLLAHPCILVSTLLLIMLLATAI
                     ANFLINILMTVFFGNHDIFTNMKQLNTKYTDYIFNFRSDAVLLYIPIWGLVFIFFGKKV
                     YQFRQRFKSLNNNEKASGRFATRKEITQQYKAIPQREHAFEGEGGLPVAMFGVYDFVTK
                     TKQYLEQRKTAIREINGITDLTADEKLELRKDKLGKMNKEFATTFFSKREFTFIDESPT
                     NNLIVGTSRSGKGEIVVLSMIENYSRSSEQPSLIVNDMKGELFSASYKTLENRGYLVEI
                     FNLDQPMESTMSFNPLQQVIDEYMKGDLGEAQEMTKQITYTLTNNEGVEDNEWNLMAGA
                     LINAMILALCEETLPKNPEKVTLYSVSNMLQTLSTKRFYKEIAIGNKVQLIEVSALDEY
                     MERFPSHSPAKTQYATVQAAPDKMRSSIIGTALKALQPFTTDTIAKLTSHTSFDINKLG
                     FPSIIDGYATKDSTFELGVQVLRDGENGIEYEEVEGIQIGVNEYGYWQYPFKTVLKVGD
                     RIETIEKDGNNQVITSYFYVDHIDDKGQVTFNQKGELDNSDITIRKFNSFPKPIAVFMV
                     VPDYNNANHGIASILVNQIVFEISKNSQLYTENQSTYRRVIFHLDEAGNMPPIPNLSQK
                     VNVSLSRGLRFNFFVQAFSQFKDKYGDAYDAIMDACQNKVYIMATQEQTLKDFSAMIGS
                     QQITVHSRSGEAGAIKSSITENQEERPLLRPDELARLQEGETVVVRNLKRQDKKRNKVM
                     SYPIFNDGKYAMKYRYQYLSDLMDTSQSIIHFRPMLKARCEHRHLQLEATLVDWDKRIE
                     EMQEGIDGQKEENKNINDINQYKKSNEEGNVAVRVKRLETLKDKVGDAVFDKITRRFER
                     YLRTYAEQGKNVNTITQKKLEELVLADSEVKEEEKTKRIEMIKKLIKEAKTT"
                     /name="VirD4-like conjugal transfer protein, CD1115 family"
     gene            16709..17161
                     /locus_tag="E3S66_RS14490"
                     /old_locus_tag="E3S66_14490"
     CDS             16709..17161
                     /locus_tag="E3S66_RS14490"
                     /old_locus_tag="E3S66_14490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000789162.1"
                     /translation="MKNIFGFVFFLSIVLLLSGCSKSGIEEISPKEAHDKLKNPKNEYV
                     IAISDLSRAGEEHIYNSKKILEKVAEEKGIKIYYAIYDSNNEKHEKDFDEYGKFKGHTS
                     NFYYAEKGKKVEDMDYKSLGVAESSKVNISAEVLGRFIDQKEEEGF"
                     /name="hypothetical protein"
     gene            17162..19003
                     /locus_tag="E3S66_RS14495"
                     /old_locus_tag="E3S66_14495"
     CDS             17162..19003
                     /locus_tag="E3S66_RS14495"
                     /old_locus_tag="E3S66_14495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="WP_160176695.1"
                     /translation="MSKEAIQKILEKYQDVLQMSEIVPNMLRSIGWYFLHFLVWITDLV
                     SNLTIQVLTLFGLLTQDSISKLILEAKPVLISVLALAIIYIGIKLMLGRPINKADIFAT
                     LVVAVLFLGSVNIGLQKGSELTKEASKAIENFDPDSKKQTDGTKVGSSMLAKSIVDVQL
                     MAEKGFPDVKTTRNNQKYNNLNASAIKHININQELEEKEIKKKESKEVLKKKLVVDEAG
                     RQKVEDLEKNWFGLGDEKYYRFHVKWFTATVGLICLALGHFLAALRVASIALEIIVNKI
                     LAIFFSHALQGERLKSTIIDILNGFVSVIMIFFCLFLYKEVVSFLNDKPTGIWLVGLIA
                     ATWFMIDGPKSIERKFGYDAGLRSPFYTMAGMYGMGKAATALATNTANGTSSMIKAVRD
                     DFSKSKRNDVNNNSNEQQSKSEQLNKASNNQNTDKQQNVKDNQNIDSNSQVNDRQNNTE
                     SNSSHNGQSNSNRQSLDEEMKNSNYGNNTFKGVGESHSQLWANRAPDGGRKKETLNDVI
                     KRTQGEKSNTPKTNQFNTNTPKANPMNAPKAQRKITDNGFSKQQNTSQNNPSPKSYKDV
                     QNVKPVQTNKPVNKSIPKSHVNKPINKNRSKNIKPKR"
                     /name="pLS20_p028 family conjugation system transmembrane
                     protein"
     gene            19014..19379
                     /locus_tag="E3S66_RS14500"
                     /old_locus_tag="E3S66_14500"
     CDS             19014..19379
                     /locus_tag="E3S66_RS14500"
                     /old_locus_tag="E3S66_14500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5592 family protein"
                     /protein_id="WP_000071066.1"
                     /translation="MSNRIPENTNVEAKITRWLYMKDVMTFLIVFVGSYILQAIRIVPE
                     SATLYMNILQLIVILTLIIRPFATNPKRRSLRVFWITVRKDRNVYAEIPYEMIEKDKEV
                     TNHGNVQNATRNYKDFL"
                     /name="DUF5592 family protein"
     gene            19333..20121
                     /locus_tag="E3S66_RS14505"
                     /old_locus_tag="E3S66_14505"
     CDS             19333..20121
                     /locus_tag="E3S66_RS14505"
                     /old_locus_tag="E3S66_14505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001240638.1"
                     /translation="MAMFKTPQETTKTSSNKTLFKEASSEKDDASSLFGKVFEEETMKI
                     SSKKDESTSTIFGDINETKIKRKKLRKKRFEYKNKPIKLFKPYRASKTFLDISNIIRRT
                     EEHTGGLYVLRDGTYMKFFQVNPKDIMSRNSHEQLYDMGVLLNMLKTYNKDNKIIALNM
                     PIDTETQRSHLIRKYEKEEVGIYRYFLEQRIKKLEYLEQSSRMERSFLAMLFGKTAQEL
                     NVNIQTYKKSMARGFPIKELTKEQEIKILYKLNNQCEEIK"
                     /name="hypothetical protein"
     gene            20141..22138
                     /locus_tag="E3S66_RS14510"
                     /old_locus_tag="E3S66_14510"
     CDS             20141..22138
                     /locus_tag="E3S66_RS14510"
                     /old_locus_tag="E3S66_14510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000100244.1"
                     /translation="MSSVYSRWRERRKVKKAIDSGTLSQSDFDIELLSQIQPRGGVNFK
                     NDFYVRKGTGYETCITIYETPTDVEDFWLGQIMTMDNTIITMDLRTKTKEEIKNNLKTG
                     MTEYLDRMHNDRDVVSRTEAEESYQELNTLLRNVRNGGESIKEVVIRLYVSGRTKDEVD
                     EKLNEIFVFLNAMDFKGTVYLNEQKFESQALTMSLTQQESVLPRIKKDIPSQTIAIGVP
                     FHSVSLNDEHGVYFGESDTGGNILLDLFYKDSRRTSYDGVFVGAKGAGKSHALKKILLE
                     EAIQGHRMRTIDSTGEFVKLVDVLGGKTISLDGTDGMINPLEVNAVAVREKVDDLGKNV
                     QEIDEVTSFNQHKHKLSTFYGLMNPDAKAKDKQLFRIVIDQFYKDIGLWSANPDKQTNI
                     TNLNPEDYPTFSELLQYLRELVYEDQEFKNVRPNISEDRLKQYQSIELTLQDIISSNGA
                     MFDGHTTIENFKQYSIINFSIRQLNAMGDEVKKAQLFNVMNLLFDEMVYFGSPQFQAYN
                     RRELKLEDAVRYRLIFDEAHNLISASETDAPVVEKCEKFIREDRKYFAGFIFASQDIKD
                     FIPEDSQEQNVAKVKTLFSQTTYRFIMRQDTSNVEKLGNVFSQELSDSELSVIPQLGTG
                     EVILNIAGVNNVKFKIDISEEENDLFGGGA"
                     /name="hypothetical protein"
     gene            22141..23247
                     /locus_tag="E3S66_RS14515"
                     /old_locus_tag="E3S66_14515"
     CDS             22141..23247
                     /locus_tag="E3S66_RS14515"
                     /old_locus_tag="E3S66_14515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="WP_000797545.1"
                     /translation="MKNRTIAKRAAKQAVKFIAHKANIALWKLWLLLGAVLFSILLTVV
                     IVGTIITAVRVEKDKQEQATSSSKGCEVVGGNLKEGGLQTFEKNAKGGALEGKSEKIVE
                     IAKKNKIPPSLFMAIIASESGWGKGANATRQNNPLSVMGNKSIQDSTYKTIEDGLEDGA
                     RNLYDLYISKGLTTPEKIGSKYAPVGAANDPSNMNARWVPTVKSNMKSLGEVEKGGTTV
                     SCDNDIPAGESIEKLKKVIEKHGGKLPKYGKKTFEPNTYAYHQCTWYVYNRRKELGLPV
                     ELSFGNGGDWADKAKAQGYKTGKTPKVGAMISWPYNSKAFGSTPYGHIAFVEEVKKNGE
                     IRVSEYNIIPFTYGERTFKLDGDETFIY"
                     /name="CHAP domain-containing protein"
     gene            23268..23879
                     /locus_tag="E3S66_RS14520"
                     /old_locus_tag="E3S66_14520"
     CDS             23268..23879
                     /locus_tag="E3S66_RS14520"
                     /old_locus_tag="E3S66_14520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000041935.1"
                     /translation="MSKNKKHANKNGKLFGSVIILLSLIGLIIYFVFQDHNELNKTVEI
                     QSKKIKSLQKNNEEKQKLIERLDNKNVVKEEEVLRRKAEDFVKVLYVTSTKTDDKKRYE
                     KAKELMDKSLADQYFGETRRSPIKYETDIQDVKIYNERYSPEKKEYHMYLTLTQAIKGS
                     SDGIDKRKIASELTLKQEGNNIWKVNKFKQFDEEKIEESK"
                     /name="hypothetical protein"
     gene            23892..24737
                     /locus_tag="E3S66_RS14525"
                     /old_locus_tag="E3S66_14525"
     CDS             23892..24737
                     /locus_tag="E3S66_RS14525"
                     /old_locus_tag="E3S66_14525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000661079.1"
                     /translation="MKELFKAFIPGKTSIRNKGSWLFYVLTVFILGSFILILASRFFTE
                     DPVTNVHTPIKKWQNTSTSGSVRINQWTWNKEKKTMDFVIEYKQELDKDVIQNVQYKII
                     PNATPDVESKYKIINQMDNKQAIRVYDVKPNFEVLVVKILSKDKESDNEEEILKVFGNE
                     KNVSIEQKKTLPTKEDYQLSFIKDDIEINKQNLKNKEKEKGELKKNIEDLNTEINLLDA
                     KKTYQISDEKEETNNQIEAKKSEIKEKENEINNVEEAEKKLQEKIDLLNKKYQATNKIS
                     "
                     /name="hypothetical protein"
     gene            24993..25247
                     /locus_tag="E3S66_RS14530"
                     /old_locus_tag="E3S66_14530"
     CDS             24993..25247
                     /locus_tag="E3S66_RS14530"
                     /old_locus_tag="E3S66_14530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001142398.1"
                     /translation="MPTKDIFIRNVNIETLERIDRLAKQKNISRNDFLLDVIEKVDPLE
                     CYRSLYAEQSHQQAQNTKVLKELADKVDRVYNIINDLEY"
                     /name="hypothetical protein"
     gene            25268..26416
                     /gene="mobP2"
                     /locus_tag="E3S66_RS14535"
                     /old_locus_tag="E3S66_14535"
     CDS             25268..26416
                     /gene="mobP2"
                     /locus_tag="E3S66_RS14535"
                     /old_locus_tag="E3S66_14535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001631996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="WP_160176696.1"
                     /translation="MPKIVTVSQFEQPNEFYEYSNYVNYMKRGEAQNNKDDFKYDVYAH
                     YMFDEEKSQNMFNEHDNFMSKKAINKIKSDFSHAQKNKGMMWKDVISFDNSSLESVGIY
                     DSKTHTLDEQKIKEATRKMMKRFEKKEGLEDNLVWSGAIHYNTDNIHVHVAAVEKVIKR
                     TRGKRKPATLKHMKSTFANELFDIKGERQKINEFIRERIVKGIRDESEPCKDKAMKKQI
                     KKVHKLLEDIPRNQRNYNNNILKYIRPEIDKITDIYIKNYHSKDFEVFKNDLKRQTNLY
                     KETYGENSNYGSYEKTKMKDLYARSGNTILKNIKELDQDLMKVKQQSTHSKSNATITKL
                     KIGKCLNQALYRTKYALRSDYDKEKNIQQYYQEFDKQSYRER"
                     /name="mobP2"
     gene            26426..26812
                     /locus_tag="E3S66_RS14540"
                     /old_locus_tag="E3S66_14540"
     CDS             26426..26812
                     /locus_tag="E3S66_RS14540"
                     /old_locus_tag="E3S66_14540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000036315.1"
                     /translation="MSKIQQRIRIEGKYLDLLTKIQRENDFKNSGEAIEYIINEYLMLK
                     ERVDETSELISNMKKITLIMNQNSKDIKTLVEFANTTAYLEGFDENRSAHSEPTSWLES
                     AKKDVETQIEEKRIRKMTNKNRRG"
                     /name="hypothetical protein"
     gene            26815..27378
                     /locus_tag="E3S66_RS14545"
                     /old_locus_tag="E3S66_14545"
     CDS             26815..27378
                     /locus_tag="E3S66_RS14545"
                     /old_locus_tag="E3S66_14545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001631997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001631997.1"
                     /translation="MENNFLISDAEPATFVKLAGNIITVETEEFEYDFRLTDAQLEQCY
                     QKLSKDNELNFIINPDKGIIVIDNDYDVTQQSEIDNIEDYFFAIEDMPITSKTCEIVKL
                     FSVKGKHYAEIETEDNEHLTLFIKEDVYQVIKDTLQSFEKTDDIDKVYFSYSPEFHKII
                     LNDMSDFDEGDLQLGNMMFGDDEQ"
                     /name="hypothetical protein"
     gene            27375..28700
                     /locus_tag="E3S66_RS14550"
                     /old_locus_tag="E3S66_14550"
     CDS             27375..28700
                     /locus_tag="E3S66_RS14550"
                     /old_locus_tag="E3S66_14550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708854.1"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="WP_000708854.1"
                     /translation="MKKAELNHFIEETSEQALKKLEEFFYSPDSVEEYISFLSQFYNYS
                     PRNQLLIANQYKGAKAIAPYKKWQSLGAQVQKGEKAIKILVPSERKTFVRDIDNKKSVL
                     PIKEATKEEKALMKKGEIKINKQLVFVKGSVFDIRQTDMPEDKYPQMIQQLRGEVTDYA
                     KKIQCLNAIAEAYNIDVKESEDSIQGARGYYTETSTGDKKIILNKDNEQAENTRTMIHE
                     LSHALLHGKDKIIETPTTLGMKEEEFQAEMTALIVGSYMGLDNNDDSIQYIYGYAKNMS
                     AEDKMMLMKNVQKVSSEMIKAINDKDANDIYLEVNKYPNEVMIKPNKTKNNTFLRNDQL
                     YTIQDANYFSKEMYSQFTPTLAHQENNKTNIIQGIPFSYAPQQTMLEQPTFYEYVKTYI
                     VSQDPSSKSKVDRAIEKDSQSIKHAQNKKVIDIYTSDNQIER"
                     /name="ArdC-like ssDNA-binding domain-containing protein"
     gene            28722..29393
                     /locus_tag="E3S66_RS14555"
                     /old_locus_tag="E3S66_14555"
     CDS             28722..29393
                     /locus_tag="E3S66_RS14555"
                     /old_locus_tag="E3S66_14555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001631998.1"
                     /translation="MNQNEQGKIYQTYLLKEFFSDKPLFNVEALTEREQNDLQHLKENL
                     NPNIKAVIEESVANVISPFYELDKATKGLREVENQMKNVENIEIKDYAFSKYEDIIYQK
                     SNQNKENFNYINQRFQIAKIEHTEPMETQLNKCEIASFEDGKIELEVANQLYQVTIPHE
                     SYLKVKEAPNRYDFMLDKSTGNIIYKEKTETIEMSNDGLEKTPRHLKKQVVDEQDNELE
                     R"
                     /name="hypothetical protein"
     gene            29417..31534
                     /locus_tag="E3S66_RS14560"
                     /old_locus_tag="E3S66_14560"
     CDS             29417..31534
                     /locus_tag="E3S66_RS14560"
                     /old_locus_tag="E3S66_14560"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859496.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_000859496.1"
                     /translation="MKTVIFAEKPSQARDYANALGISHKKDGYIEGVNPMFDGGVIITW
                     GFGHLVELKLPKDYSNPINNWDLKNLPYRPSPFEYKVSEGKSKQFNIVKSLFKDADILI
                     NATDIDREGSNIFYSTLKLTGVKNKTIKRLWINSLVEKEIKKGFQQLQNNHQDYQNYQE
                     AYARQTSDYLIGMNLSPVYSKIFQLQGVQDVFSIGRVQTPTLYMIYERYLAIENFKPET
                     FYEIFGEFESKNGCYKGKAKIKTTDKQEIINLGEKHNLKDAKEGIITKLETQEKRTSSP
                     KLHSLSTLQSKINKQYKYSPEKTKNIVQSLYEKKILSYPRTDCNYITSEEYLYLKENLQ
                     SLMNVYNKHFSIVYDKPRARYVNNEKVKEHYAIIPTSQIPTPQNIEKLSQDEKYVLDEV
                     VSTTLSMFANDYVYDETKIETNVNQLIFYTTGHTEIQKGWKILFKHKGNEKSPEQQLPK
                     LIKNECVKANIYSKKGITQSPKLYTEGQLITLMKSCGKYLDDEEAEILKEIQGIGTEAT
                     RDGIIQSLKNKNYIKIEKNKVHITAKGILLCKAVKGSLLASATMTAAWEKRLKLIGQGQ
                     ANTDNFIDITMKFIDKEIKAYQEKCEDKSIINQSNIVAKDNEFGECPNCTDGQLIDKNK
                     IISCTNCEQVFFKNFYQKKLTDKQIQELIFNGKTSKKLKLKNKAGKTYEAYLILTEDKK
                     TGTKRYNISFD"
                     /name="type IA DNA topoisomerase"
     gene            31576..32925
                     /locus_tag="E3S66_RS14565"
                     /old_locus_tag="E3S66_14565"
     CDS             31576..32925
                     /locus_tag="E3S66_RS14565"
                     /old_locus_tag="E3S66_14565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001632000.1"
                     /translation="METPIKDILKEKYKIDIDKEALHELIAKQVDKELLKRMSSKSREN
                     LGLSGYFTELQQSITGIKARLHEKFTGETINKNIHGIKAFLSDYAINPKIISENIKELL
                     GKSKDNVVDAFSKIKTLFKEEQQNLRHTELNNEILLSEKFSDLQDMMKDSYNIINHAEN
                     IKELRNYKQITRLEIIEQTLALKDNPETENKYNFNNFSKHIDWSNQDNQTQMLELYNYL
                     KDANEAIHFSDPYSIDNDYNKLQLEQFTLQGIQKIEASINAKDLNESRLNHLENNRNTS
                     LNFTENNLKNFNKELKGVHRSLTKESEQAIKENKVIELEREKEIYEAGKIQESELFQTL
                     NNQNTFAVTPEKEPSELEKANFVGIEQGEIIVEVDENLYALTLNDKDKEKIQKNTDIFE
                     FTYNTKTGEFKYSENKENSVVKSNQNVISNNQNPLPKEYIELAEQENYER"
                     /name="hypothetical protein"
     gene            32980..33996
                     /locus_tag="E3S66_RS14570"
                     /old_locus_tag="E3S66_14570"
     CDS             32980..33996
                     /locus_tag="E3S66_RS14570"
                     /old_locus_tag="E3S66_14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043806.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3991 and TOPRIM domain-containing protein"
                     /protein_id="WP_000043806.1"
                     /translation="MSKQSYTNEEKEHARKTDIREIGEAYGLTFKKEGKYDRCIEHDSL
                     ILKGQSYYWNSKGVKGHGGLSFCIDVLDMDFKEAMSILTQDGFSQYKNDNFSIKEKKTL
                     NYNTQTEMEDSTRAYNYLVNERCLDPKLVRWGFNTGVIAQDKQNNVCFKWLDNENNIVG
                     VDKRGTGRKAFKQIVEGSKQHSGFHIDIIQDKNIGIRNVVITESPIDALSYYDSHRDLK
                     QTRIASLSGLKLETFKQHILDVGKYNLKLGEDPKEYPLESIVLAVDNDEAGKNFVSSIV
                     NTYENDFTIDLPLNSKDWNEQLKKDKAITDGKTLYQKNEIKEQLKEQTHNEKDDREI"
                     /name="DUF3991 and TOPRIM domain-containing protein"
     gene            33999..34604
                     /locus_tag="E3S66_RS14575"
                     /old_locus_tag="E3S66_14575"
     CDS             33999..34604
                     /locus_tag="E3S66_RS14575"
                     /old_locus_tag="E3S66_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136103.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004519 - endonuclease activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="WP_160176697.1"
                     /translation="MTEINIYNILLLIFMLVIAYKLMPVIYRFIKKKKIQALYRRAHII
                     DIDKMDGIEFEYYLEALFLKLKYKPIVTKASRDYGADLILKKENKKIVVQAKRSNSKIG
                     IKAVQEIYTAQRFYNADEAWLVTNSFYTKSAVELGKACDIVMKDRTSLSKWIISINPEF
                     SNNEKCPRCNHKLVVRTGKNGQFLGCSNYPNCKYTKNI"
                     /name="restriction endonuclease"
     Typing          24773..24936
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="98.788"
                     /coverage="99.0"
                     /evalue="1.88e-77"
     Typing          8945..10048
                     /name="rep_cluster_765"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="84.463"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          25266..26413
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.217"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          20142..22135
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.699"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tatgttaagg tacagtaata ccaaattagc ttttacagtc ttattttttt gttcttcttc
       61 ctttctctgc attcttttca ctaatatcac cccctttcaa aatttatatt attttttgaa
      121 agacttgata cactgtaata tttgaaaaca catgacacaa aaaccaataa ttattatgag
      181 tattagtaag taagtcatct taaatcctcc ttgatttttc ttttagaaat tatttatttt
      241 ttcgtgttgt gtagccactg aaacaagccg ttacgtttga ggttgcaagg gtacaagcaa
      301 taaaagtttt tagactggcc gtatggccac aaataaaaag ttttttgccc cttgcaatat
      361 cacgtaggct tgttaaaagc acaatctttg attgtgcgtg tgagcgtatc aacacaaaaa
      421 ataaattcta aaaaatgaaa taaagggaaa gtgatacctc actttccctc catttttgaa
      481 tttggttttt aaatgtgaat gtgatgtgca tagctaatac atcacattca ctcattttga
      541 tttttgcttt gttcctattg tttatttaat attttattcc ttttttatta ggaatttctt
      601 ctagtaaatc atctacgtcc atatcagtca taattaaatc gtcaaagttt aaagttttag
      661 atgctatttc ttcccaatct ttaaaacact catattcttt ataatttata tacacatgcg
      721 atatttcttt aataatttgg ttattattta aatctaatgt aacctgaatt tcaaattcct
      781 cattatctcc ttttgtagta tatgccaaag gacattgtaa gtttgaatca aaaacttctt
      841 catcttcgtt ataacattca aattctaaat ttttatattc cttgatgttt tcgcatattt
      901 tcaaataaat ttcaagtttg tttttatcca tttttttaac tccttttttc ttttagaaat
      961 tatttatttt tttcgtgttg tatagccact gaaacaagcc gttacgctgg agattgcaag
     1021 ggtacaagca ataaaagttt ttagactggc catatggcca caaataaaaa gttttttgcc
     1081 ccttgcaata tcacgtaggc ttgttaaaag cacaatctct gattgtgcgt gtgagcgtat
     1141 caacacaaaa aataaattct aaaattttac aaaaaaagaa agtgattata tcactttctt
     1201 tccttaacta tacgataaac agtagagcga cttactcctg tttttttagc aatctcttct
     1261 ccagtcatca tttgttcatc gtataagaac ttaatttctc gtttcttatg gtctggtaaa
     1321 gacggtctac ctcctaatct acctcttgcc ctcgcagcag ctaacccttt ttttgtacgc
     1381 tcacttaata agttagcttc aagttcagca aaagcactca tcatcgtgaa aaacattttc
     1441 cccattgcgt ctttcgttga aacgttcata tcaataattt gtaaatcaat cccgttatca
     1501 tcgagccatt gtgataattc aatcaattgc tttgtcgttc tacctaaccg gtcaagctta
     1561 tagataacta atgtgtctcc ctctcgtaaa taatctaaac acttatcaag ctctgtacgt
     1621 ttgactttcc ggccacttat tttttcacta aagatacgtt cacacccaaa ttctttaagt
     1681 gtatcaattt ggccgtcaag actttgatct ttcgttgata cacgtgcata accaatttta
     1741 gccatttaaa tattacctct cttcatcgtt ttattagtac ttacacacta aggttaactc
     1801 tcgatgcaaa taaacaagtc tgtcatcgtc taaaaactcg tatattttga attttatgat
     1861 acatagatta taacacaagt taaaggaatt atggccaaaa taaaatcccc tttaaattca
     1921 atgataaatt tcttaatcta tcttcttaat ttatcattag gggattcgtc tcaaaaacgt
     1981 tcgtttttgg tcatacgaaa tattattctt ttttcgtttc tttcttctta ttagttttta
     2041 aaatcaataa aactgatact actatgagta cattaggaaa aattgatata ttcaatttaa
     2101 agagataatt aactataagg aatataatgc ctaaaattaa taacaatact tttcttgatt
     2161 tagttaatag cattcttttt tagcctcctt ttttcaataa aatgcaaata tatcataaat
     2221 tttcgctttt gaaatgaata taaataactc taaggctaat ataaaagtta aaagactata
     2281 taccatgata tcaattacta aaggtctaag aaatttttaa atataaatac taactagtcc
     2341 caacattgat agtaataaca ataataatat tattaaaata aaaaatgtac gtgtggtgtt
     2401 gtcgataaaa ggagcaataa aactaacttt aaaagtgttt ttaattccat taccgctcaa
     2461 taacgaagtg taaatgaata gtatataact aattgaataa gaaactgcta caagcaatat
     2521 tattgtgtaa ataattggaa ctaaaaaaat taataaatcc ataaattatt accacctttc
     2581 tcttatttat cttcaaatta cttcctttaa aaaagattat catttgcatt cgttgtaaaa
     2641 aggattcggt atcttcaaga ccattttacc ctaatttttt tcttgattat actctaaaga
     2701 aaagaacata cgctcgaatg cacctatata atcaaacctg ttatattcat ataaagacgt
     2761 cccttttggg tacaccatta tatgacgctt ttcttttgaa agtttaatct tacccccgtc
     2821 atacttaatt tgctttaatg cgttttcaag acctaattca tcaaaaatta ttttaacgtg
     2881 cttcaattcg tctacaatgt ctgatatttc tgtattaatt tttaaatcgt atggatcttt
     2941 tgcaaaaccc gtgttaacgt ctaaatttaa ggcaaggttt tcatctacgg caatacattt
     3001 tcctttttct tctatatgac cctgcttatc tttaacataa atagttttaa cctcatataa
     3061 catttcttgt tcattattat ttacttggtc tattgcattg cttaaatctt ttataaagtt
     3121 tcttatattt ttaggcaaat tgacactaga tagttcttcc ataaatgact tatctttaaa
     3181 tatctcactc ttgttttcta gataaaattg atacaacaga tttataactt caaattttgc
     3241 atttgttact tctcgctctc cagagctcaa tttttttaac acattttctg atatgcctgt
     3301 gcattcgctt atttctttta atgtaatagg acttcttaat aacatttcga cattttttat
     3361 aacttcattt aaatttattt gactcactag acaccctccc attagttcca cttttttaaa
     3421 ttatatcatt atatttcgga accgtaaaca ttttaatata acaagacgag actttctcgc
     3481 ccatattatt atgtatcaag catatttatt attcacaata acgaacatat gttctataat
     3541 ttacttgagg tgttaaaaat gtatgtgatt aatccagaac tgcccgagcc atataaatat
     3601 gaaactgatt atagaaaaat tcctaaagaa ttacttaata gcaatattcc taagggaaga
     3661 gataaagtca aatgggctcc atttaagacg gtatctgacc agtataagtt gttagacgaa
     3721 tatatagaag aacaaaacaa gattgaaatg cctttgttgt ctgacgatca attacagata
     3781 cttaacgaaa cagtttacta caacagtatg aacaatattc ttacagaatt aagttattgg
     3841 gataacggct atataaattc aatggaatgc tacattaaca aagtcgatgc attagaacat
     3901 gtgatgattg ttagtaatga aagtaaagaa actaaaataa aaattccact aaatagtatt
     3961 attaatatta actaataaga acttatggcg ataaaattat tggttcttat tagttaattg
     4021 ttatgataaa aattctttag tcttttcaca atcactaata acgctgtaaa tgggtctaca
     4081 ttctttccac atatttcaca tgttactagc ttatatcttt cgcttattcg atatttagcc
     4141 ttgtctccgc actggcattc caccttgtca tttttcacct ttattataga gtcaaatttt
     4201 atgacgtttt ccggtaaatt tttattacta tcactcattt gttaacagct cctttttcac
     4261 acgtcattca aataaccgtc tccgtcccaa tatttcagaa cggcgttatt ataggctttc
     4321 gcacattctt tttcatctac aaatctacct agatattttt tctctccctc tgcatagata
     4381 ctagcaaccc atttgttatg tttactatca taagacacac ctttatattt tgaactacta
     4441 ttcttttgag gtgctcgata tctgaaagaa tgtttatcag cacctaaatt tcttcttgta
     4501 aaatcattgt tcttaacctt ttgataagca tattgattgt taagtatgaa tactggtagt
     4561 gctgtttttt tgcctagtat ttgggctaaa aaacgttgtg tgtcgtgagc gtatgattta
     4621 tgccatttgt aaaagtttac acgttcaaaa tcttcatcat caacaatgat ataatcatca
     4681 atattttcta tatatatttt cttcatgcta ttccaccttg gtatttatta aataactaag
     4741 ttcaactaat taaatagtta aataaattaa aaccaaaact aaaatcaact aagaatatta
     4801 gtaatataaa aagacctgct gatatgacta ttagttaata taagtgatcc aattaaacct
     4861 attacaaccc ctttgacaat ctcattaaac aaccatataa tcgaatcact atctattaca
     4921 atatctaaaa gcatactatc actccttttt atagctgttt tttttattag tttaacctat
     4981 catttcatct gttttttctg ttaatgccat tttgtaacgt atttctactt ttcgcatttc
     5041 catttctgac aatctttttc tttcaatttc agttaatcct atcatcatat ctataaggtc
     5101 aatcaatgtt tctttattca taataaatgc ctcctattga ttaattagca tttataaatt
     5161 atgattatct ttgtagtgtt tttataaatg cttgagtcgt agcttccccc agaagtctac
     5221 ggcttttttc ttattattct ttagccacta aaaccatgat aaaagccaat taatgatttt
     5281 tttaaagaac tcaacaatag agtcccaaat tttctgtaag aaattacggt tttcttctgt
     5341 atttagttct ttagccttat ctagcaaatt acctgctttg tctttaatat tgcttgctaa
     5401 atcttttgct tgtttttcgt atgctttagg gtctttgttt agtatttctg aattagaaac
     5461 attaaccatg atattattaa tcacattaat ttgattatca cttaaaatct tattcaagcc
     5521 attctcttta agaatatcat taacaatctt actaatatct tcacgagtta aattctttcc
     5581 gtcttgcttt tcactcgcta tttctttctt catttcagca atagcattat ttaacgcctc
     5641 atctgaataa cctttctgcc ctttattctg ctcactaatt gaagctaggt cattcatttc
     5701 tttattagcg ttttgtacat catctttatt taaactattg ccattttctt cataagcctt
     5761 atatatacct gttaaagcac cctcgcctgt taccttatcg atcgaagcaa ctttgatttc
     5821 agaatcttgt atacctgctg tgatagccgc atttgtatac tgttcttttg taattctagt
     5881 aatgttttct ggcgtttcta tatcaactgt tacgcctttt ttaaactttt ttggtgtgat
     5941 agttgcacta gaatgaataa agcttaaatt gttatttcca gtatatttag caacatcatt
     6001 agttgttata gaaatttctt tatagccatc atcaacctca agcttctttt tagtttcttc
     6061 caattgttga ctgttcaagt ctgcaccttt aatgaagata tcttcattaa gcttgttact
     6121 atctgcaaat gctacaccac cagtgtttaa caataaaata gacgcaattg ttccgcttgc
     6181 tattaatttc ttgttcatct taactactcc tttggttata gtattttcat acaaccgttt
     6241 caacggttga tcttgaaaat actatttgtt agttttattt tgagacaagt taatttcctc
     6301 gcctcttatt tgtttataaa gtaactcaat agctttcgta tagacttctt gcttactatt
     6361 taattttaaa tcaaatttca attcatttgc tatgtcgtcc acatttttat acaactgcac
     6421 tgtacgtcta tgtttatgag aaggactttc gtattttttg actttttcat tcatatttag
     6481 gctacctcca atgttatgtt tactttaatt atagggtaat tatgaggagg aaaccaatcc
     6541 ccctcaatct atgtctctat tctcactatt tgagagctat ctacataatc ctcattatta
     6601 taagttttat aaaaatcatc tattaaagat aattcgttag tataatcttc aatattgtta
     6661 taaagtttat ttaaattccc tatataaata tagtagttaa tttccaaatt ctctttatag
     6721 tgattataat acctttcaaa gttttctatt ctctgttcaa taacatcttg aattaccaag
     6781 ctaacatcta tatctttcga taagatagtt ccatcatttt gttttgcaat atatgcagtc
     6841 atcattttca aatcctccat attcttgtta taatatggac ggaacaacgg caattgttcc
     6901 gtcaactttc ttttttatgc tgagggtaag ttatttattt aacttatcct ttttaacaat
     6961 aaacttcatc agtataaaca aaatgcttat ctgctctaat catactttca attcgcttat
     7021 agtctctctc gtctgcacag tctatcattc ccatatacaa accattttca attactgtaa
     7081 caccctcgca accgaacata tctttcgcaa cttctaattt gtaatctttt ccatgtgctt
     7141 caaaataatg tgttttgttt tccatttgta aaaccctctt tcttttattt gttaattata
     7201 ttataacaca acgggtacac cttgtacacc cgttataccc gtttttttaa aaaatttcct
     7261 ctaatataaa taaagcacct attatatagg cgctttaaaa taaatttagt tttataaata
     7321 tgtgtttctt ctatatattc ttaattagct catttataaa ttctgacgat gatgcatatc
     7381 cattttcatt tgctaatcgc tctattttct ttcttacaga tggttctaac gtaaattgaa
     7441 acctctcttt tttttctttg ttgtttcgtt ttaatatacc aaaacttcta gcattaaatt
     7501 ctggtgactt tgcttcttct aatgctgtat taatatcttt tcctttattg ttttctctct
     7561 tattaaaagc catagtatct ctcctagtat ttatcattat atttatatgc ataaccgaca
     7621 acattcttgt gtgtatttaa atcattatat ttatacacac tactatcaac acttcaaaca
     7681 gctgtagttt attataatta tgcgcgtata aatgtgtaag ttttgtatta aaaccttatg
     7741 tttacatttt tttaatcact tcacaacttt ttacaaagtc cttaaaaaac gttctgtttt
     7801 tactaagtat atttttatct ttcgaaaaat caactattgg ttttttttcc attacacttt
     7861 tagtaattaa ttctttatca ggaaaatatg ttatatattt attattcgaa ttcatttctt
     7921 caataaaatg attagatgat ttagtattat gcttaaccat attgccgaca taatataatt
     7981 tagctgttac ataactctct cttgttctga aatcaattaa atcatttttc aacttatcta
     8041 ttctgtattc aatgttagaa tttgaatcat cactaaaacc actaggttta tttggagaaa
     8101 taactttgtg actaactgct attgcatttc ttgttgatgt actaaaatct gggtgtgtat
     8161 ctataattat ataatcatac ttttcaatat tatatttatc gtagttatca tctaaccaca
     8221 tatataattg catatcttta ccatctactg tactcattac tctttcatac tcatctaatc
     8281 ttaaaaaacc actaattaaa tctatatttg ttttaacttt atgaactttt acttcttcgt
     8341 ttatattaag cccatcaatt ttattgaaaa ttgataatac cgtattttct tgctcataca
     8401 catttaatag ttgagataga ttacattggt gatccatatc aataagaaga actttttttc
     8461 ctacagaagc taaatattcc gaaaagttat aagataatgt tgtttttcca acgccgccct
     8521 ttatagcagc aaaagtaatt atttccattg cttccacctc caacaaaaac ataccactaa
     8581 tacacataat tatcaacaca aaagtgtgta tttaattaaa tatataaatg tgtatttata
     8641 tcattataat ttatacacac aactatacac actattaaat ttatgttatg ctatagctgt
     8701 attccttata taagggggaa tatatgtgtt atgtagaata tcatttctac aatcctttat
     8761 tctataaagt aaagctgtaa gaagattcaa aatacatttt acaaataaca gcaacatgtt
     8821 attattaatt tataatataa aaaaaagagc aactactgga aatagttact ctcaggtaat
     8881 agaacgtctg caaacgttta tttaatatat tttcgatact tgtattatat aatgaataat
     8941 atcttagtgc aagcacctaa atcattaaat aaaagtaaag ctaaataaaa gcgttttatt
     9001 acctcttacc aaactaaaat atggaaagag gtttttatta tgtctgaaca aagatttaat
     9061 atccaacaac aatatagaga aaaattttac caactaccga aagtattttt tactaacgaa
     9121 aaatatatgc aattaagtaa tgatgcaaaa attgcttatg ctttgttaaa agatagatta
     9181 gaattatcaa ttaaaaataa ttggtttgat gaaaatggcg atatattttt catcttcaca
     9241 aacgataaac ttaaaaatat attaaattgt catgatggaa aattaacaaa aataaaaaaa
     9301 gaattatcta aagctgatct tttagaacaa gtaagatgtg gtcaaggtaa accaaataaa
     9361 ttatatttga agaatcctgc aattactaaa gaagatgttt atgaaattaa aaaacaagaa
     9421 gaaacaagtg gcgaacctag tcatgacgct gaaatgcgaa aatcgcattt caagaaatgc
     9481 gaaaatcgca tttcaagaaa tgcgaaaatc gcacaacaag aaatgcgaaa atcgcacact
     9541 aatgatactg atttaagtaa tacttattat attgagactg agaataatga tatgaatgac
     9601 ttgaatgatg tagagtccaa aaatgaaatt agtaatcatt caaatcattc aaatcaattt
     9661 acacataatt ttgatgataa agattataaa gaaatactac tgcaagaatt tccagagcaa
     9721 ctaactaatt atttattaaa atatgattat agagatttag aaatcataaa ggctgttatt
     9781 cttaaagcaa aaaaatcttt taattcaaat catgatgata atttttatat gctagaacat
     9841 attgaaaatg aaatattaat ttctttaaaa agacttaaaa aagctataca tgatagacga
     9901 gttaaaggcc aaaaggaaac aataaagtca atgcaagggt atttaatgca aacaattcta
     9961 actgaacttg aagaattaca ttcaacggat atgagaagaa agaatttaaa aaacagttct
    10021 tggaatattt tttagccaaa ttgattaata ttacaaacat acttttttgt aaaaatgaaa
    10081 ggagagacaa ctatgcgaaa taaaaactat ataggcggtc taacaaaaga aaatttaaaa
    10141 ggttttgtca ttttagtgct cattttttta tacgttttat ctgccttgct taatttaaca
    10201 ggcttttttt gggggtatgt ttttatgcct gtgtttgcta tatggagtat atacatgatg
    10261 ttttttagag gttattttat tccggttgta aaaatactct ttatcatcac tttaaccaca
    10321 atcaaatttg tgtttatggt tttctttatt atggcaatag cctcttcttt gtctgacaaa
    10381 aaatattaaa acaatctagg gtgtaaatat attaaaaatt atttcggatt aaaaagaaat
    10441 atagtaaaat aaaaatgtgc aacatttgag gctgttacac atttagtctt tatggtctat
    10501 tggaatattc aaatattttg ataaaaacaa attaagcact tgagatcttg ttaatccgtg
    10561 tttctgagct actgcctcaa ttttttcatt acttgaataa ctaattgtat aagttgcttg
    10621 tacagtatta tagctttttt taccgtaatt attgtaactg ctaaaatcga tattgcttaa
    10681 ttcagtttct tgaatgattt tttctacaaa atctgaatta ttcaaatcgt ttattgcact
    10741 tgttattttt attaactgtt ttgtagtaga tttgattcta aaaacacgtg gatatttttg
    10801 cactttttat cataactcct tgcttaaaat attaagtaat gctataatta tattaaccat
    10861 taatggttac ttgaaccttg ataattacat atgcgtgccc ctgtattata aggaattcaa
    10921 tgcagataag gtatacgact attggttaaa cgggtaatcc taaacctgtg aatttcattc
    10981 ttattaaact attctaatca aacactgttt tgtgtataaa ctgggagggg aagtcccgat
    11041 gaaccagatg aaacaaatac agcctgaata gcgcgagcgg gaagacgaaa gaaccgcaag
    11101 ggtcgggcag tgaaaagtgc tgacaatccg aacccatatt ttatatttta taatttatat
    11161 atttcaatca caacatcaag agatactaga taatggtaat aacttttact catggaggtg
    11221 ttttttatgc tttgttataa gaaaaataaa cgttttgatt ttatagcctt ttactttttt
    11281 gctgatgaaa tacgtacgtt tgatggtaaa acttatcgaa tcaaaggtat gcgttgtcag
    11341 agaattgatc ataaacgttt ggatataaac gagagaaaaa cactacgcca tttgtcagaa
    11401 gttatttata aaacgaaaac ggtatttaat gacaattatg gactaattgc ttatcgtaag
    11461 aaagtaagtc aagaactaaa aagcgtcaaa aacatcagta taagcaaaag tgtttaaaca
    11521 gtgtttgctt attttaataa gagtgaaatt tacttaccgt aaaatttatt gactgtttga
    11581 aaagacagat tagttaaaag tatgctagcg ctacattaaa tagcctatag gcacatatat
    11641 gtaattatca aagaactaga ataatatttt tgtgaggact ttaaagaaaa gtcctttttt
    11701 agtataaagc aaaatttaaa aaagaataag gtgtttcacc taattttctt tttagaataa
    11761 aagaaagggt aaattattat gtctaaaatt acacaaaatg atttaaatca attaaaaaag
    11821 caagtgacag aaataatgaa agtaactgga gaaacacata acgaatggct gtataaccaa
    11881 tatcaaaatt atttatcaga aaataccgat gttgttatgg aagccttgcg tttttattct
    11941 gaaaataaaa ataatacagc ttgggaggaa taaaacatgt ttaacggact taatgaaaaa
    12001 attgtagccc ttattaacga tgctcaacca cttatcatta cattattggc actttcgata
    12061 tttgtttctg gtgctgtaat gatgtttggg gatactggtg tacgctgggc aaagagaacg
    12121 ttgataggcg caataattgg tgcggtatta tctggtggag cccttgttta tgcacgttca
    12181 tttaaaaaaa tagttaatgt cagtgcagta tttccgtcag cgacagaaac taagtttgca
    12241 gttatagata cattacaaat aatttttatg taaacggaca aattaataat ttgttcgttt
    12301 tctttttata aaggagagat aaaacttgtt gagaataaaa acgaaatcgt ttcacatcaa
    12361 aaatcaaagt gatttttcat tagaagaaat gatgtcctat acagaagata tggaagcagg
    12421 gaaatttcca gaatcactag ataaatttga ttacgtaatg tatgacgaac aaacatatga
    12481 ggatatttta gagtcaacgt acaaagtgaa tagtggttat attaatatac aacaacaaat
    12541 ttatacattg cttaaagcaa ctgcgcctga cacagaagaa ttgaaaagac tgaaacgaca
    12601 gtacttaatt gctctacagg aagtgggtaa gtcatatcgt gacaaaaaag ttgctatgaa
    12661 taaaaagaaa aataatccag acaatacaaa atttcaatac caaagacaaa acaatgcaaa
    12721 taaaactaag caaaaagaaa tacttgaaaa attaaaggga aagcgcgggt taatgttttt
    12781 ggggctgatt gtttttgtaa tgttgttagt atatatactt gttgttacag atccaaacaa
    12841 aaaaggagca tctgacgttg cgacaaaaga agaaatatac caacaagctc ttttaggaga
    12901 agaagaaaaa gccattgata attttgctaa attagaccaa gagacattaa ccaaaaaaga
    12961 caaacaaata tatgcgcaat tattagctca aaaagaagag tatgataagg cggttaagtt
    13021 gtctgatgca aaatttgtag aagcgtattt aattagcaga gactattata gcgctttaga
    13081 agaatttaat aagaaatatc caactaataa tgggaagttt gatttagcta tacaccagaa
    13141 taagttttct gatgccatta attacagtca aggtatcgat aaaacaaaca atagaaaaaa
    13201 acaactggta aaagcgtata tagagacaga caatttaaat aaggcgaaag aattagcagc
    13261 gacaacggaa gacaaagaag ttacaaaaat gattgcagat gaacaaaaca agcgcttgaa
    13321 agggctagaa gaagccgtta agagtaaaga agatgattta aagaaagcga aagataaaaa
    13381 agaaaagaaa tctgatattg aaaataaaga aaaagcgctt aaagaagcaa acgagaattt
    13441 ggaaaaattc aaaaaagaac ttaaataaat agaggtgaaa caatgctaaa tgagtttaaa
    13501 tttataggac gtattgctag agacttagaa ctaacaacta aagagaacat gcaagcgaga
    13561 tgtaacttca cactagcagt aaataatgca tatggcactg actttttaaa cataacggct
    13621 tttgataaaa cagcagaaaa tttagtgaaa tataatcaaa aaggagacat ggtttatgtt
    13681 gaaggttatg taagcacgaa taaaaaaagt gttaatggcg ttgataaata ttatatgaac
    13741 cttgttgctg gacgtattgt gtatcttagt aataaaaaag tagaagaatc agaaaatgaa
    13801 ttagagcata gcactgataa tttagataac ttaacatttg acgataaaca acatacagaa
    13861 gtgaatgaaa ataacacaac tttccagaaa gcaaaaggtt tcgttactga agacttgcca
    13921 ttttaagagg tgattttata atgaggtttg gttcaaaaga caaacatggc tatagaagga
    13981 aaaagttatc attttctcaa aataaacatt tgcttgcaca tccatgtata ttggtaagca
    14041 cattattatt aattatgtta ctggccactg caattgcaaa ttttttgatt aacatcttaa
    14101 tgacagtgtt ttttggaaat catgacattt tcacaaatat gaaacaactg aacacgaaat
    14161 atacagatta tatatttaac tttcgttcag atgctgtgtt gttatatata ccaatttggg
    14221 gactcgtctt tatatttttt ggaaaaaaag tatatcaatt tagacagcgt ttcaaatcat
    14281 taaacaacaa cgaaaaagcg tcagggcgat ttgccacacg aaaggaaatt acgcaacagt
    14341 ataaagcaat accacaaagg gagcatgcat ttgaaggaga aggtggtttg cctgtcgcaa
    14401 tgtttggtgt atatgacttt gtgactaaaa cgaagcaata tttagagcaa agaaaaactg
    14461 ctattagaga aattaacgga attactgatt taacagctga tgaaaaatta gaattacgca
    14521 aagataaatt aggaaaaatg aataaagaat tcgctactac atttttctca aaacgcgaat
    14581 ttacatttat tgatgagtca ccaaccaata atttaattgt gggtacatct cgttctggta
    14641 agggagaaat tgttgtttta tcaatgatag aaaactattc aagatcttca gaacaaccat
    14701 cattaattgt aaatgacatg aagggagaac ttttttctgc atcgtataaa acgttggaaa
    14761 atagaggata tctagttgag atctttaatt tggatcaacc tatggagtca acgatgagct
    14821 tcaacccatt gcaacaagtt attgatgaat atatgaaagg cgatttggga gaagcacaag
    14881 agatgacgaa acaaattaca tatacgttaa ccaataacga aggtgtagag gacaacgaat
    14941 ggaacttaat ggctggcgca ttgattaacg ctatgatact tgcactatgt gaagaaaccc
    15001 taccgaagaa cccagaaaaa gtcacacttt atagtgtgtc taatatgtta caaacattaa
    15061 gcacaaaaag gttttataaa gaaattgcaa ttggaaacaa agttcaatta attgaggttt
    15121 cggcattaga tgagtatatg gaaaggttcc ctagtcatag tccagctaaa acgcaatatg
    15181 cgacagttca agctgcacca gacaaaatgc gttcgtctat catcggaacg gctttaaagg
    15241 cattacaacc atttacaact gacaccatag ccaaattaac aagtcacacc tcttttgaca
    15301 ttaataaatt aggatttcca agtattattg atggttacgc aaccaaagat agtacatttg
    15361 aattgggcgt acaagtgtta cgagatggtg aaaacggcat tgaatacgaa gaagtagaag
    15421 gcattcaaat aggtgtaaat gaatatgggt attggcaata tccgttcaaa acagtactta
    15481 aagtcggaga tagaatagaa acaatagaga aagacggaaa taatcaagtt atcacaagtt
    15541 atttttatgt tgatcatata gatgataaag gacaggtcac atttaatcaa aaaggcgaat
    15601 tagataactc agatattacg ataagaaagt tcaatagttt tccaaaacca atagcggtat
    15661 ttatggttgt accagattat aacaatgcta accatggtat agcgtctata ctcgttaacc
    15721 aaattgtttt tgaaatttcg aaaaattctc agctatatac ggaaaatcaa tcaacgtatc
    15781 gacgcgttat tttccacctt gatgaagcag gtaatatgcc tccgataccg aatttatctc
    15841 aaaaagtgaa cgtatctctt tcaagaggat tacgttttaa tttctttgtt caagcatttt
    15901 ctcaatttaa agataaatac ggtgatgcat atgatgcgat tatggacgct tgccaaaaca
    15961 aggtgtatat catggctacg caagaacaga cattaaaaga ttttagcgca atgattggaa
    16021 gtcaacaaat cacagttcat agtcgttcgg gtgaggcagg agcaattaag tcaagcatta
    16081 ctgagaatca agaagaaaga ccgttactac gaccagatga attagcgcgc ttacaagaag
    16141 gtgagacagt cgttgttaga aacttgaaac gacaagataa aaaacgaaac aaagtaatgt
    16201 cttatccaat tttcaacgac ggcaagtatg caatgaaata tcgttaccag tacttatcag
    16261 acttaatgga tacaagccaa agtatcattc attttagacc tatgttaaaa gcgcgatgtg
    16321 agcacaggca tttacaactt gaagcgacat tagttgactg ggataaacgt attgaagaaa
    16381 tgcaagaagg gatagatggt caaaaagaag aaaataaaaa cattaatgac attaatcaat
    16441 ataaaaaaag caatgaagaa ggcaatgttg cggtgcgagt taaacgttta gaaactttga
    16501 aagacaaggt aggagacgct gtttttgaca aaattacaag gcgtttcgaa aggtacttaa
    16561 gaacctatgc agaacaaggc aaaaatgtta ataccataac acagaaaaaa ctagaggaac
    16621 tggttttagc agatagcgag gtaaaagaag aagaaaagac taagcgtatt gaaatgatta
    16681 aaaaattgat caaggaggca aagacgacat gaaaaatata tttggattcg tgttttttct
    16741 aagcatagta ttgcttttgt cgggttgttc aaaatctggg atagaagaga tatcacctaa
    16801 ggaggcacat gataaattaa aaaatcctaa gaatgaatat gttatcgcaa ttagtgattt
    16861 gagtagggct ggagaagaac atatttataa ttctaaaaag attctagaaa aagtagcaga
    16921 agaaaaaggg attaaaattt attatgcaat atatgactca aacaatgaaa agcacgaaaa
    16981 agattttgat gaatatggca agtttaaggg gcatacatca aacttttatt atgcagagaa
    17041 agggaaaaaa gtagaggaca tggactacaa gtctttaggt gtagccgaat cttcgaaagt
    17101 taatatatcc gctgaagtgt tggggcgatt tattgaccaa aaagaagagg agggctttta
    17161 gatgtctaag gaagcaatcc aaaaaatatt agaaaaatat caagatgttt tacaaatgtc
    17221 tgaaattgta cctaacatgt tacgctcgat aggttggtac ttcttacatt ttcttgtttg
    17281 gattactgat ttagtttcaa atcttactat tcaagtttta acactttttg gattacttac
    17341 acaagatagt attagtaaat taattcttga agcaaagccg gtattaattt cagtattagc
    17401 gctggccatc atttatatag gtatcaaatt aatgttagga agaccgatta ataaagctga
    17461 tatttttgct acattggttg ttgcagtttt gtttttaggt agtgtgaata taggtttaca
    17521 aaagggctct gaattaacaa aagaagcaag taaagctata gaaaattttg atccagatag
    17581 taaaaaacaa acagacggca ctaaagttgg ttcttcgatg cttgctaaaa gtattgtaga
    17641 tgtacagttg atggcggaaa aagggtttcc agatgttaaa acgacaagaa acaatcaaaa
    17701 atataacaac cttaatgcaa gtgcaattaa gcatatcaac attaatcaag aattagaaga
    17761 aaaagaaatt aaaaagaaag agtcaaaaga ggtacttaag aaaaagttag tcgtcgatga
    17821 agcaggtcga caaaaagttg aagatttgga aaaaaactgg tttggcctag gtgacgaaaa
    17881 atattatcgt tttcatgtga agtggttcac tgcaactgtg gggcttattt gtttagcttt
    17941 gggtcacttt ttagccgcgt tacgtgttgc aagtattgcc ttagagataa ttgtaaataa
    18001 aattttagct attttctttt cacatgcact acaaggagaa cgccttaaat caacaattat
    18061 cgatatttta aacggttttg taagtgttat tatgattttc ttctgtttgt tcttatacaa
    18121 agaagttgtt agtttcttaa acgataagcc aacaggtata tggttggtag gacttattgc
    18181 tgcgacatgg tttatgatag atggtccaaa gtccattgag cgtaaatttg gttatgatgc
    18241 cggtcttaga tcaccgtttt acacgatggc cggtatgtat ggaatgggta aggcggcaac
    18301 tgcgctagcg acaaatacgg ctaatggaac aagtagtatg attaaagcag tgagagatga
    18361 tttttctaaa tcaaaaagaa atgacgttaa taataacagc aatgaacaac aatctaagtc
    18421 ggaacaactc aataaggcct cgaataatca aaatacagac aaacaacaaa atgttaaaga
    18481 taatcagaat atagatagta atagtcaagt taacgatagg caaaacaaca cagaatcaaa
    18541 cagtagtcat aacggccaat ctaacagcaa cagacagtct cttgacgaag agatgaaaaa
    18601 ttctaattac ggaaataata cattcaaagg tgttggcgaa agtcattcgc aactatgggc
    18661 aaatagagcg ccagacggag gacgaaagaa agaaacgctt aacgacgtta tcaaacgaac
    18721 acaaggagaa aaatctaaca caccaaagac taatcaattt aatactaata cacctaaagc
    18781 taaccctatg aatgcgccta aagcgcaaag aaaaataact gataatgggt tttcaaaaca
    18841 acaaaacaca agtcaaaata acccatctcc aaaaagttat aaagatgtac aaaatgtaaa
    18901 gccggtacaa acgaacaaac ctgtaaacaa atcaattcca aaatcacatg tgaataaacc
    18961 tattaataaa aatagatcta aaaatataaa accaaaacgt taggaggttt ttgatgtcca
    19021 atagaatacc agaaaataca aacgtagaag ctaaaattac gcgttggctt tatatgaaag
    19081 atgttatgac gtttttaata gtatttgttg ggagttatat tcttcaggca attcgaattg
    19141 tacctgaaag cgccactttg tatatgaaca tcttacaact tattgttata ttaactttaa
    19201 taatacgtcc gtttgcaaca aatcctaaac ggagaagcct aagggttttt tggattactg
    19261 taagaaaaga tagaaatgtt tatgcagaaa ttccatatga aatgattgaa aaagacaagg
    19321 aggtcacaaa tcatggcaat gttcaaaacg ccacaagaaa ctacaaagac ttcctctaat
    19381 aaaactttat ttaaggaggc atcatcagaa aaagatgatg cttcttcttt atttggtaag
    19441 gtttttgagg aagaaactat gaaaatatct tctaaaaaag atgaatcaac ttcaactatt
    19501 tttggagata ttaacgaaac caaaatcaaa aggaagaaac tacgtaaaaa aagatttgaa
    19561 tacaaaaata agcctataaa gctttttaag ccttatagag catcaaaaac ctttttggat
    19621 atatctaaca tcatcagaag gacggaagag catacaggtg gcttatatgt acttagagat
    19681 ggtacctata tgaaattctt tcaagtgaat ccaaaagata ttatgagtag aaattcacat
    19741 gagcaattat atgatatggg cgtgcttctt aacatgctta aaacttacaa caaagacaat
    19801 aagattatcg cgttaaatat gccgatagat acagaaacgc aaagaagcca tttaatcaga
    19861 aaatatgaga aagaagaagt aggtatatac aggtacttct tagaacagag gataaaaaaa
    19921 ctggaatatt tagaacagtc atcaagaatg gaacgctctt ttttagcaat gttatttggc
    19981 aaaacagcac aagaacttaa tgtaaacatt caaacatata aaaagtcaat ggctagaggt
    20041 tttccaatta aagaattaac gaaagaacaa gaaataaaaa tactttataa gttaaataat
    20101 caatgcgaag aaattaagta atatttaagg gggttttcac atgagcagtg tgtatagcag
    20161 atggagagaa cgaagaaaag ttaagaaggc gattgatagt ggcacactat cacaatctga
    20221 ctttgatatt gaattactct ctcagataca accaagaggc ggcgttaatt ttaaaaatga
    20281 cttctatgta agaaaaggca cggggtatga gacttgtata actatctatg agacgccaac
    20341 tgatgtagaa gatttttggt taggacaaat tatgactatg gataatacca ttattacaat
    20401 ggatttgagg acaaaaacaa aagaagaaat caagaacaat ttaaaaacag gtatgacaga
    20461 atatttggat cgtatgcata atgatagaga tgttgtttca agaactgaag ctgaagaatc
    20521 gtatcaagaa ctcaatacat tattaagaaa cgttcgaaat ggtggagagt cgataaaaga
    20581 agtggtgata agactgtatg tgagtgggag gacaaaagat gaagtcgacg aaaaattaaa
    20641 tgaaattttt gtttttctta atgcaatgga ctttaaaggc actgtttatc ttaatgagca
    20701 aaaatttgaa agtcaggcac ttacgatgag cttaacacaa caagaatctg tactaccaag
    20761 aataaaaaaa gatataccgt cacaaacaat agcaataggc gtgccgtttc attcagtatc
    20821 gttaaatgat gaacacgggg tgtatttcgg agaatcggat acgggaggta atatcctgct
    20881 tgatttgttc tataaagaca gtagacgtac ctcatatgat ggcgtttttg taggcgctaa
    20941 aggtgcgggg aaatctcacg cacttaagaa gatattatta gaagaggcaa tacaaggtca
    21001 cagaatgaga accattgatt ctacaggaga atttgtaaaa ttggtagatg ttctaggagg
    21061 gaagactata tctttagatg gtacagatgg catgataaac ccgctagaag taaatgcagt
    21121 agctgtaaga gaaaaagttg atgatttagg caaaaacgtg caagaaatcg atgaagtcac
    21181 atcttttaac cagcataagc ataaattaag tacgttttat ggattgatga atccagacgc
    21241 caaagctaaa gataagcagc ttttcagaat tgttattgac caattttaca aagatattgg
    21301 cttatggagt gctaatcctg ataagcaaac caatatcact aacttaaatc ctgaagacta
    21361 tcctactttt tcagagttgt tacagtactt acgcgaatta gtatatgaag atcaagaatt
    21421 taaaaatgtg agaccaaata tatcagagga taggttgaaa caatatcaat caatagagtt
    21481 aacgcttcaa gatattattt catctaatgg cgcaatgttt gatggccata caacgattga
    21541 aaactttaag cagtactcta ttattaactt ctctattaga caattaaatg caatgggtga
    21601 cgaagtaaaa aaggcacaat tatttaacgt aatgaacttg ttgtttgatg aaatggttta
    21661 ctttggctct cctcaatttc aagcttataa cagacgcgaa ttaaaattag aggatgcggt
    21721 aaggtataga ttgatttttg atgaagcgca taatttaatt tctgcaagtg aaacagatgc
    21781 acctgtagtt gaaaaatgcg aaaaatttat tcgagaagat agaaagtatt ttgctggatt
    21841 tatatttgct tctcaagata ttaaagactt tattccagag gattcacaag aacagaatgt
    21901 tgcgaaagtg aagacattgt tttctcaaac aacgtatagg ttcattatgc gacaggacac
    21961 ttcaaatgtt gaaaaattag gaaatgtatt ttcgcaagag ttgagtgatt ctgagttaag
    22021 tgtaatccct cagttgggaa caggtgaagt tattttaaat attgctggag taaacaatgt
    22081 aaagtttaaa attgatatta gcgaagaaga gaatgacttg tttggtgggg gtgcgtaata
    22141 ttgaaaaatc gcactatagc aaaaagagca gccaaacaag ctgtaaaatt tattgctcat
    22201 aaagcgaata ttgctttatg gaaattatgg ctattattgg gtgctgtgtt attttctatt
    22261 ttattaacgg ttgttattgt tgggacaatt ataactgcgg ttagagtaga aaaggacaaa
    22321 caggagcaag ctacatcatc gtcaaaaggt tgtgaagttg taggaggtaa cctaaaagaa
    22381 ggaggactac aaacttttga aaaaaacgct aaaggtggcg cgttagaagg taagtcagaa
    22441 aaaatagttg aaattgctaa aaagaacaaa ataccacctt cactttttat ggcgattata
    22501 gcttctgaat ctggatgggg aaaaggcgca aatgcgacaa gacaaaacaa cccactatct
    22561 gtaatgggta acaaatcaat tcaagattca acctataaaa ccatagaaga cggattagaa
    22621 gatggcgcaa gaaatttata tgacttatac atctctaaag gattaacaac acctgaaaaa
    22681 ataggatcta aatatgcacc tgtaggtgct gctaatgatc caagtaatat gaatgcgcgt
    22741 tgggttccaa ctgtaaaaag taatatgaaa tcattaggag aagtagaaaa aggcggcaca
    22801 acggttagtt gcgacaacga cataccagcg ggagaatcta tcgaaaaatt gaaaaaagtt
    22861 attgaaaaac atggtgggaa gttgccgaaa tatggaaaga aaacatttga accaaacaca
    22921 tatgcttatc atcaatgtac ttggtatgtc tataaccgta gaaaagaatt aggtttgcct
    22981 gtggagctat cttttggcaa tggcggtgat tgggcagaca aagcaaaagc acaaggatat
    23041 aaaacaggaa aaacccctaa agtgggtgct atgatatctt ggccatacaa ttcaaaagca
    23101 tttggttcaa cgccatatgg tcacatcgct tttgttgaag aggttaagaa aaacggagaa
    23161 ataagagtaa gtgaatataa cattattcct tttacttatg gagaaagaac cttcaaatta
    23221 gacggtgatg aaacatttat atattaaaat agtagaggtg gaaaatagtg tctaaaaata
    23281 aaaagcatgc gaataaaaat ggtaaactgt ttggctccgt aattatacta ttatctttaa
    23341 taggacttat aatttatttt gtttttcaag accacaatga attgaataaa actgtagaaa
    23401 tacaaagtaa aaagataaag agtttacaaa agaacaatga agaaaaacaa aagttaatag
    23461 agagattaga taataaaaat gttgttaagg aagaagaagt acttaggagg aaggcagaag
    23521 actttgtaaa agtattatat gtgacaagca ctaagacaga tgataaaaaa aggtacgaaa
    23581 aagctaaaga attaatggat aaatcacttg ctgatcagta ttttggagag acaagacgtt
    23641 cacctataaa atatgaaaca gatatacaag atgttaaaat ttataatgaa agatattctc
    23701 ctgaaaagaa agaatatcat atgtatttga cattaactca agctataaaa ggtagttcag
    23761 atggtataga taaaagaaaa atagcttcag aattaacact taaacaagaa ggcaataaca
    23821 tttggaaagt gaataaattt aaacaatttg atgaagaaaa aatagaagaa agcaaataaa
    23881 gaggtggtat tttgaaagaa ttatttaaag cttttatacc aggtaaaact tctataagaa
    23941 ataagggcag ttggctattt tatgtgctaa ctgtctttat tttaggttcg tttatattga
    24001 ttttagctag tcgatttttc acagaggatc cagttactaa cgttcataca cctataaaaa
    24061 aatggcaaaa tacatctact tctggcagtg tgagaattaa ccaatggaca tggaacaaag
    24121 agaaaaaaac aatggatttt gttattgaat ataagcaaga attagacaaa gatgttattc
    24181 aaaatgttca atataaaata atacctaatg cgacccctga tgttgaaagt aaatataaaa
    24241 ttataaatca aatggataat aaacaagcga ttagagttta cgatgtcaaa cctaattttg
    24301 aagttttagt agttaaaatc ttaagtaaag ataaagaatc agataatgaa gaggagatat
    24361 taaaagtgtt tggtaatgaa aaaaatgtat caatagagca gaaaaaaaca ttgccaacga
    24421 aagaagatta ccagttatct tttatcaaag atgatattga aattaataaa caaaatttaa
    24481 aaaacaagga aaaagaaaaa ggagaattaa agaaaaatat agaagattta aatacagaaa
    24541 ttaatctgtt agatgccaaa aaaacatatc aaatttcaga tgaaaaagaa gaaacaaaca
    24601 atcaaataga agccaaaaaa tctgaaataa aagagaaaga aaacgaaata aataatgtag
    24661 aagaagctga gaaaaaacta caagaaaaaa tcgatttgtt gaataaaaaa tatcaagcaa
    24721 caaacaaaat aagctaaaaa actagtgtca caaaaataag acaaaatcta catgtagtgt
    24781 cacaaaaccg tgacaaacac aatatatagt gtcacgaaaa tgtgacacta ggtgttttta
    24841 tgatatcact atgaaatgtc ctaaaaccct tggaatgtct ggctttgcca gacctatcat
    24901 tgtccgatga tagcaaattc cccttatgct cttacgaggt aacaggcgtt ttatagactt
    24961 ttagttactt tttataggag gttatcaaaa ttatgccaac aaaagatatt tttattagga
    25021 acgttaatat agaaacattg gagaggattg accgattggc aaaacaaaaa aacatatcaa
    25081 gaaacgattt tttattagat gtaatagaaa aggttgatcc gctagaatgt tatcgaagtt
    25141 tgtatgctga acaatcacac caacaagctc aaaatacaaa agttttaaaa gaattagcgg
    25201 ataaagtaga ccgagtttat aacatcatta atgatttaga atattaagtt aatacgtagg
    25261 tgatatgatg ccaaagattg taacagtatc tcagtttgaa caaccaaatg aattttatga
    25321 atacagtaat tatgttaatt atatgaaacg tggagaagca caaaataata aagatgattt
    25381 taaatacgat gtttacgcac actacatgtt tgacgaagaa aaaagtcaga atatgtttaa
    25441 tgaacatgat aactttatgt cgaaaaaggc gataaataaa attaaaagtg attttagtca
    25501 tgcacaaaaa aataaaggta tgatgtggaa agatgttatc agttttgata attcatcttt
    25561 agaaagtgta ggtatatatg attcaaaaac acatacatta gatgaacaaa aaattaaaga
    25621 agctacaaga aaaatgatga aaaggtttga gaaaaaagaa gggcttgaag acaatttagt
    25681 ttggtctggc gcaattcact ataatacgga taatatacat gttcatgttg cagcagtaga
    25741 aaaagtaatt aaacgcacta gaggaaaaag aaagccagca acactaaaac atatgaaatc
    25801 tacctttgcc aatgagcttt ttgatataaa gggagaacgt caaaaaataa atgagtttat
    25861 acgcgaaagg atagttaaag gtattcgtga tgaatctgaa ccatgtaaag acaaagccat
    25921 gaaaaagcaa ataaaaaaag ttcataagtt attggaagat atcccaagga atcagcggaa
    25981 ttataacaat aatattttga aatatatcag accagaaata gataaaataa cagatatcta
    26041 tataaaaaat tatcacagta aagattttga agtttttaaa aatgacttaa aaagacaaac
    26101 caatttgtac aaagaaactt acggcgaaaa ttctaattat ggctcatatg aaaaaacaaa
    26161 aatgaaagat ttatatgccc gttcgggtaa tacaatatta aagaacatca aagaattaga
    26221 ccaagattta atgaaagtaa agcaacaatc tacacattca aaatcgaatg caactataac
    26281 aaagttaaaa ataggaaagt gtcttaatca agcactatat agaacaaaat atgcattgcg
    26341 cagtgactat gataaagaaa aaaatataca gcaatactat caagaatttg ataagcaatc
    26401 atatagagaa aggtagttaa atgatatgtc taaaattcaa caacgtataa gaattgaagg
    26461 aaagtatttg gatttattaa caaaaatcca aagagaaaat gactttaaaa atagcggtga
    26521 agctattgaa tatattatta atgaatatct aatgttgaaa gaaagagttg atgaaacatc
    26581 agagttaata agtaatatga agaaaataac attaatcatg aatcaaaatt caaaggatat
    26641 taaaacacta gttgaatttg cgaatacgac tgcctattta gaaggttttg acgaaaatag
    26701 aagcgcacat agcgaaccta caagttggtt agaaagtgcg aaaaaagatg ttgaaacgca
    26761 aatagaagaa aaaagaatta gaaagatgac taataaaaat aggaggggtt aaacgtggaa
    26821 aataattttt taattagtga tgctgaacca gctacatttg tcaaattggc tgggaatatt
    26881 ataacggtag aaacagaaga atttgaatat gacttcagac ttacagatgc acaattagaa
    26941 caatgttatc aaaagctaag caaggataat gaacttaatt ttattatcaa tccagataaa
    27001 gggatcattg tgattgataa tgattatgac gttacgcaac aaagtgaaat agacaatatc
    27061 gaagattatt ttttcgccat tgaagatatg cctataacgt caaaaacttg tgaaattgta
    27121 aaattattta gcgttaaagg aaagcattac gcagaaatag aaacagaaga taatgaacat
    27181 ctaactttat ttattaaaga agatgtttat caagttatta aagacacgtt acaaagtttc
    27241 gaaaaaacag atgatataga caaagtatat ttttcatata gtcctgaatt tcacaaaata
    27301 attttgaatg atatgtctga ttttgatgaa ggtgatttac agttggggaa tatgatgttt
    27361 ggagatgatg aacaatgaaa aaggctgagt taaaccattt tattgaagaa acttcagaac
    27421 aagctttaaa aaaattagaa gaattttttt attctccaga cagcgtagaa gaatatataa
    27481 gctttctttc tcaattctat aattactccc ctagaaacca attattgatt gctaatcaat
    27541 acaaaggcgc aaaagcaata gcaccttata aaaagtggca atcattaggc gcacaagtac
    27601 aaaagggaga aaaagctatt aagatacttg taccatctga aaggaaaacc tttgtaagag
    27661 acatagataa taaaaaatct gttttgccaa taaaggaagc aacaaaagaa gagaaagcac
    27721 ttatgaagaa aggcgaaatt aaaataaata agcaactggt ttttgtaaaa ggcagtgtat
    27781 ttgatattcg acaaacagac atgcctgagg ataaataccc tcaaatgatt caacaattac
    27841 gtggagaagt aactgattat gcaaagaaaa tacagtgcct aaacgctatt gctgaagctt
    27901 acaatataga tgtgaaggaa agcgaggaca gcattcaagg cgcaagagga tactatacag
    27961 aaacgtcaac cggagataaa aaaatcatct taaataaaga taatgaacaa gcagaaaaca
    28021 caagaacgat gatacatgaa ttaagtcatg cgcttttaca tggaaaggat aaaataattg
    28081 aaacaccaac gactttggga atgaaagaag aagagtttca agcagaaatg acagcgttaa
    28141 ttgtaggtag ctatatggga ttagataata atgatgattc aatacagtat atatatggat
    28201 acgcaaaaaa tatgtctgcc gaagataaaa tgatgttgat gaaaaatgtt caaaaagtat
    28261 ctagtgaaat gataaaagcc attaacgata aagacgctaa tgacatttat ttagaagtta
    28321 acaaatatcc aaatgaagtt atgattaaac caaacaaaac taaaaacaat acttttctta
    28381 gaaacgatca gctatatacc atacaagacg ctaattattt ttctaaagaa atgtatagtc
    28441 aatttacacc tacgttagcg catcaagaaa acaataaaac aaacattata caaggcatac
    28501 catttagcta tgcacctcag caaacgatgt tagaacagcc aacattttac gagtacgtca
    28561 agacatatat cgtctcccaa gatccaagtt ctaaatctaa agtggataga gctattgaga
    28621 aagactcgca atctattaaa catgcacaaa acaaaaaagt tattgatatt tatacttctg
    28681 acaatcagat agagcgctaa aaataaagga ggctataaat gatgaatcaa aatgaacagg
    28741 gtaaaattta tcaaacatac ttattgaaag aatttttttc ggataaaccg cttttcaatg
    28801 ttgaagctct aacagaaaga gaacaaaatg acttacaaca tttaaaagaa aacctaaatc
    28861 ccaacatcaa agcagtgatt gaagagagtg tagcaaacgt tatttcacct ttttatgagt
    28921 tagacaaggc tactaaaggt ttaagagaag tagaaaatca aatgaaaaat gtagaaaata
    28981 tcgaaataaa agattatgca ttttcaaaat atgaagatat tatttatcaa aaatcaaatc
    29041 aaaataaaga aaacttcaat tatattaatc aacgttttca aatagctaaa atcgaacata
    29101 cagagccaat ggaaacacaa ttaaacaaat gtgaaatcgc aagctttgaa gatgggaaaa
    29161 tagagcttga agttgcaaat cagctttatc aagtcactat cccccatgaa tcatatttaa
    29221 aagtaaagga ggcaccaaat agatacgatt tcatgctaga taaatcaaca ggaaacatca
    29281 tatacaaaga aaagacagaa actatagaaa tgagcaatga cggcttagaa aagacgccaa
    29341 gacatcttaa gaaacaagtt gtagatgagc aagataatga attagaaaga taaaacataa
    29401 gaggtgacgc atcaatatga aaacagttat ttttgctgaa aaaccctcac aagcaagaga
    29461 ttatgccaat gctttaggga tatcacacaa aaaagatggt tatatcgaag gtgtaaatcc
    29521 tatgtttgac gggggagtca taatcacatg gggctttggc catctagtgg aattaaaatt
    29581 gccaaaagat tactcaaacc ctataaataa ttgggattta aaaaacctac cttatcgtcc
    29641 aagtccattt gaatacaaag tatcagaagg taaaagcaag caatttaaca ttgttaaatc
    29701 tttatttaaa gacgctgaca ttttgatcaa tgcaacagat attgataggg aaggaagtaa
    29761 tatcttttat tcaacattaa aactgaccgg agtcaaaaac aaaaccataa aaagactatg
    29821 gataaactct cttgtagaaa aggaaataaa aaaagggttt caacaattac aaaataacca
    29881 tcaagattat caaaattatc aagaagctta cgcaagacaa acaagcgatt atttaattgg
    29941 tatgaatttg agccctgtat attcaaaaat atttcaattg caaggtgttc aagatgtttt
    30001 ctcaatcggg cgtgttcaaa cgccaacgtt atatatgatt tacgaacgtt acttagcaat
    30061 cgaaaacttt aaacctgaaa cattttatga aatatttggg gagttcgaat ctaaaaatgg
    30121 ttgctataaa ggaaaagcca aaataaaaac aactgataaa caagaaatta ttaatttggg
    30181 agaaaagcac aatttgaaag atgctaaaga aggcataatt actaaactag agactcaaga
    30241 aaagcgcaca tcatcaccta aactacactc tttatcaaca ttacaatcta aaatcaataa
    30301 acagtataaa tatagtcctg aaaaaactaa gaatattgtt caaagtttgt atgagaaaaa
    30361 aatactttct tatccaagaa cggattgtaa ctacatcacg agtgaagaat atctttattt
    30421 gaaggaaaac ttgcaatcac taatgaatgt atataacaaa catttttcaa ttgtgtatga
    30481 taagccaaga gctcgatatg taaataacga aaaagtaaaa gaacactatg caattatacc
    30541 tacctctcaa atacctacac cacaaaacat tgagaaatta agtcaagatg aaaaatatgt
    30601 gcttgatgaa gtagtaagta ctacactaag tatgtttgcg aatgactatg tatatgacga
    30661 aacaaaaatt gaaaccaatg taaaccaact tattttttac acaactggtc acaccgaaat
    30721 acaaaaaggc tggaaaatcc tatttaaaca caaaggcaat gaaaaatctc cagaacaaca
    30781 attaccaaaa ctcataaaaa atgaatgtgt aaaggctaat atttattcaa aaaaggggat
    30841 tactcaatct ccaaagcttt atacagaagg tcagcttata acactgatga aaagttgcgg
    30901 gaagtattta gacgatgaag aagctgaaat attaaaagaa atacaaggta ttggcacaga
    30961 agcaaccaga gatggaatta tacagagtct aaaaaataaa aattatatca aaatcgaaaa
    31021 aaataaagtg cacattacag caaaagggat tttgctttgt aaagcagtaa aagggagtct
    31081 acttgctagt gctacaatga cagcagcgtg ggaaaaacgc ttaaagctca tcggacaagg
    31141 acaagcaaat actgataact ttattgatat aacaatgaaa ttcatagata aagaaattaa
    31201 agcataccaa gagaaatgtg aagacaagtc gataatcaac caaagtaata ttgttgcaaa
    31261 agataatgaa tttggagaat gccctaactg tacagatggc caactcatag ataaaaacaa
    31321 aattattagt tgcacaaatt gtgaacaagt attcttcaaa aatttttatc agaaaaaatt
    31381 aacagacaaa caaattcaag aattgatttt taatggtaaa acctcaaaaa aattgaaatt
    31441 aaaaaacaaa gctggaaaaa cgtatgaagc atatttaatt ttgacagaag ataagaaaac
    31501 aggaacgaag agatataaca ttagttttga ttaatacgat caatataaat aatatctaga
    31561 attgaggcga ataatatgga aacacctatc aaagacattt tgaaggaaaa atataaaata
    31621 gatatagaca aagaagcttt gcacgagcta attgcaaaac aagttgataa agaactttta
    31681 aaacgtatga gttcaaaatc gcgtgaaaac ttaggactaa gtggttattt cactgaatta
    31741 caacaatcta ttacaggcat taaagcgcgc ttacatgaaa aattcacagg agaaaccatc
    31801 aataaaaata tacatggaat caaggctttt ctctccgatt atgccataaa tcctaaaatt
    31861 atcagcgaaa atattaaaga gttgttaggc aaaagtaaag ataacgtggt agatgcattt
    31921 tcaaaaataa aaacactttt taaagaggaa caacaaaatt taaggcatac agagctaaat
    31981 aacgaaatat tgttaagtga aaagtttagt gacttacaag atatgatgaa ggatagttat
    32041 aacataataa accatgcgga aaatattaaa gagttaagga attataaaca aataactcga
    32101 ttagaaatta tagaacaaac actagcgctc aaagacaatc ctgaaacaga aaacaaatat
    32161 aacttcaata atttcagtaa acacatagat tggagtaatc aagataacca aacgcaaatg
    32221 ttggaactat ataattatct taaagatgct aatgaggcaa ttcatttcag tgatccttac
    32281 tctatagata acgattataa taaattacaa ttagagcaat tcactctaca aggcatacaa
    32341 aaaatagaag caagtataaa cgcaaaagac ttaaatgaaa gtagacttaa tcatttagaa
    32401 aataacagga atacatcttt aaattttaca gagaataact tgaaaaattt taacaaggag
    32461 ttaaaaggcg ttcatcgctc acttactaaa gaatccgaac aagctataaa agaaaataaa
    32521 gttatagaat tagagcggga aaaagagata tatgaagcag gaaaaataca ggaatcagag
    32581 ttatttcaaa cattaaacaa tcaaaatact tttgctgtaa ctccagaaaa agaaccatct
    32641 gagttagaaa aggcaaattt tgttggaata gagcaaggag aaataattgt agaagttgat
    32701 gaaaatttat acgcgttaac tttaaacgat aaagataagg agaaaataca aaagaataca
    32761 gatatttttg aatttaccta taataccaaa acaggagaat ttaaatattc cgaaaacaaa
    32821 gaaaactctg ttgtaaaatc caaccaaaac gttatatcaa acaatcaaaa tcctcttcca
    32881 aaagaatata tagaacttgc cgaacaagaa aattatgaaa gataaaaata tttagaacag
    32941 cccttgatta aggactgttc ttttttggag gtttttaata tgagtaaaca atcctataca
    33001 aacgaagaaa aagaacatgc aagaaaaact gacattagag aaataggaga agcttatgga
    33061 cttacattta aaaaagaagg caaatatgat agatgcatag agcacgattc attgattcta
    33121 aaaggacaaa gttattattg gaactctaaa ggcgttaaag gacatggcgg tttatctttt
    33181 tgtatagatg tattagacat ggattttaaa gaagcaatgt ctattttaac gcaagatggt
    33241 ttttctcaat ataaaaatga caatttttct ataaaagaaa aaaagacttt aaattacaat
    33301 acacaaactg aaatggaaga tagtacaaga gcttataatt acttagtaaa tgaaaggtgt
    33361 ttagacccaa aacttgttag atgggggttc aatacaggag ttatagctca agacaaacag
    33421 aacaatgttt gttttaaatg gttagataat gaaaataaca ttgtcggggt agataaacgt
    33481 ggtacaggga gaaaggcttt taaacaaatt gtagaaggat caaagcaaca tagcggattt
    33541 cacattgata tcattcaaga taaaaatata ggtattcgta atgttgttat aacggaaagt
    33601 cctatagatg ccctcagtta ttatgactcg catagggact taaaacaaac tcgaatagcc
    33661 tcactgtcag gccttaaatt agaaactttt aaacagcaca ttttagatgt tggcaaatat
    33721 aatttgaaac taggagaaga cccaaaagaa tacccactag aaagtatagt tttagccgtt
    33781 gataacgatg aggcagggaa aaatttcgta agtagcatcg ttaatactta cgaaaatgac
    33841 tttacaatag atttaccttt aaactctaaa gattggaacg aacagctaaa aaaggataaa
    33901 gcgataactg acggaaaaac gttatatcaa aaaaatgaaa taaaagagca attgaaagaa
    33961 caaactcata acgaaaaaga tgatagggag atataaacat gactgaaata aacatttaca
    34021 atattttact actaatattt atgttagtta tcgcatataa gttaatgccc gtcatttata
    34081 gatttattaa gaagaaaaaa attcaagcat tatatagaag agcacatata attgatatag
    34141 ataaaatgga cggcatagaa ttcgaatatt atctcgaagc attgttttta aagttaaaat
    34201 ataagccaat tgtaacgaaa gcttcaaggg actatggtgc agacttaata ttaaaaaaag
    34261 aaaataaaaa aatagttgta caagcaaaac ggagtaacag taagataggt attaaagctg
    34321 tgcaagaaat atacaccgca caacgttttt acaatgccga tgaagcatgg cttgtgacta
    34381 atagttttta tactaaaagt gcagtcgagt taggtaaggc gtgcgatatc gttatgaaag
    34441 atagaacaag cttatctaaa tggattatta gtataaatcc cgaattttca aataatgaaa
    34501 aatgtccaag atgcaatcat aaattagtag ttagaacagg caaaaacggc cagtttttag
    34561 gctgttctaa ctatcctaat tgtaagtaca caaaaaacat ttaagcgatt ggatagttac
    34621 acatgtgtaa tttaccgaag agcgctttat tatattaatt gaacagttaa accattaaaa
    34681 taatgttctt ttaatctttg aaattgtttg catttaatca ttataaaacc tacaatataa
    34741 aatttaatag attcaaacac gtaaggaata gtaataaaat aaacacaagt ttattgtaat
    34801 tttccatttt aaacctccta tgttataata gaagaaaaga aataggggac gtgaacccct
    34861 atttgaagaa ctataatact ttgccaagta tctgtaagat tgtataagc
//
