LOCUS       NZ_CP047834             8034 bp    DNA     circular CON 18-DEC-2023
DEFINITION  Staphylococcus aureus strain UP_926 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP047834
VERSION     NZ_CP047834.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN11175620
            Assembly: GCF_009912255.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 8034)
  AUTHORS   Dilthey,A., Meyer,S. and Kaasch,A.
  TITLE     Increasing the efficiency of long-read sequencing for hybrid
            assembly with k-mer-based multiplexing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8034)
  AUTHORS   Dilthey,A., Meyer,S. and Kaasch,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JAN-2020) Institute for Medical Microbiology and
            Hospital Hygene, University Hospital Duesseldorf, Moorenstrasse 5,
            Duesseldorf 40225, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Unicycler Hybrid Assembly v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 43x / 446x
            Sequencing Technology :: Illumina MiSeq / Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/17/2023 03:54:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,776
            CDSs (total)                      :: 2,694
            Genes (coding)                    :: 2,605
            CDSs (with protein)               :: 2,605
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 51 of 89
            Pseudo Genes (incomplete)         :: 32 of 89
            Pseudo Genes (internal stop)      :: 17 of 89
            Pseudo Genes (multiple problems)  :: 11 of 89
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047834.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8034
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="UP_926"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
     gene            complement(233..418)
                     /locus_tag="E3S92_RS13775"
                     /old_locus_tag="E3S92_13775"
     CDS             complement(233..418)
                     /locus_tag="E3S92_RS13775"
                     /old_locus_tag="E3S92_13775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466616.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIHFLNKNGEWYYFEVRSVWRGRHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            567..662
                     /locus_tag="E3S92_RS13780"
                     /old_locus_tag="E3S92_13780"
     CDS             567..662
                     /locus_tag="E3S92_RS13780"
                     /old_locus_tag="E3S92_13780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_110183608.1"
                     /translation="MTLLFVYVIAPVFVGCCITLFQFWLEQRSKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(804..1661)
                     /locus_tag="E3S92_RS13785"
                     /old_locus_tag="E3S92_13785"
     CDS             complement(804..1661)
                     /locus_tag="E3S92_RS13785"
                     /old_locus_tag="E3S92_13785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458740.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_053037997.1"
                     /translation="MSGETVVYQNEMNLVPLRKFTSTEIDIFFSLCNKLKEQDIKELAI
                     PFEELRHLSNYYHRSLKRFVKDLEHVYDKMLTLTYTERSGLSFKKFVLFTGYEVDVDEK
                     NLIVSINPKLKHVLNEITADFTKFELKEMTNLKSTYSKNMFRLLKQYKHTGYFKIQIED
                     FRERLDIPNSYRMTHINQKVLAPIIKELGFIFNNLNINKVKAKKGRKIEWLEFTFDAEK
                     RIHNKREPQMANIGKSRQYISREKTPKWLEERTYEKTPQREYDPQLEKEREAFLKQLEM
                     NWEE"
                     /name="RepB family plasmid replication initiator protein"
     gene            complement(2376..2852)
                     /locus_tag="E3S92_RS13790"
                     /old_locus_tag="E3S92_13790"
     CDS             complement(2376..2852)
                     /locus_tag="E3S92_RS13790"
                     /old_locus_tag="E3S92_13790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000683603.1"
                     /translation="MKHYIQRIDSDNLKQDFKTAMQEELKDIKSETENMVKQFQVSQIE
                     LQTSNNEYAKTIEARLNKNETAIKQYDQAVNKLTKGLTSMFFIVALVMVACLVLSPLSD
                     VLGVHYFYEWINHVLKTGHSAWRYFIVILYLIPYILLWLLIRGILSAYKRVSSF"
                     /name="hypothetical protein"
     gene            complement(2893..3900)
                     /locus_tag="E3S92_RS13795"
                     /old_locus_tag="E3S92_13795"
     CDS             complement(2893..3900)
                     /locus_tag="E3S92_RS13795"
                     /old_locus_tag="E3S92_13795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_000246204.1"
                     /translation="MATTKLSATKSTSRAINYAEKRAVEKSGLNCDVDYAKSSFKASRE
                     LYGKTDGNQGHVIIQAFKPDEVTPEQCNQLGLELAEKFAPNHQVAVYTHNDTDHVHNHI
                     VINSINLETGKKFNNNKQALRDLRNFNDEVCRNHGLSVPEKDTARLRYTQTEKAIADPN
                     IKSTAQYSWKDEIREAIDQSQATNIDELKTHLSQYGIEIERVTPKSITYRHLAEDKKVR
                     GRRLGENYNKGGIEDGFERQIQRRQQERDSEHDYQPKRRTSNRDESTERDTSITQSDWD
                     RFAKDTNELERSRKAAESARLAHEKARRDREERIQAERATRKNINNDRDHGYEL"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(3882..4265)
                     /gene="mobC"
                     /locus_tag="E3S92_RS13800"
                     /old_locus_tag="E3S92_13800"
     CDS             complement(3882..4265)
                     /gene="mobC"
                     /locus_tag="E3S92_RS13800"
                     /old_locus_tag="E3S92_13800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_000003344.1"
                     /translation="MSEQNIFVASDTVNGQIHKPNRKAPKQISFRVSESEYLKLKQSAE
                     TLNMSVPAFVKKKAQGTRLVVPKLDKTTRQSLASDLGKLGSNANQIAKYCNQHQYDAPN
                     YEALERNISELRERLDDIWQQLN"
                     /name="mobC"
     gene            4926..5132
                     /locus_tag="E3S92_RS13805"
                     /old_locus_tag="E3S92_13805"
     CDS             4926..5132
                     /locus_tag="E3S92_RS13805"
                     /old_locus_tag="E3S92_13805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008855822.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_025174767.1"
                     /translation="MNNIKHYRKEMNFSQQELANKVEVTRQTISLIELGKYNPTIKLCI
                     SIAKALQVDLNKLFWEMSDNSEE"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(5604..5699)
                     /locus_tag="E3S92_RS13845"
     CDS             complement(5604..5699)
                     /locus_tag="E3S92_RS13845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB family leaderless bacteriocin"
                     /protein_id="WP_188348922.1"
                     /translation="MGAVIKVGAKVIGWGAASGAGLYGLEKIFKK"
                     /name="GatB family leaderless bacteriocin"
     gene            complement(5731..5826)
                     /locus_tag="E3S92_RS13850"
     CDS             complement(5731..5826)
                     /locus_tag="E3S92_RS13850"
                     /inference="COORDINATES: protein motif:HMM:NF038165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB family leaderless bacteriocin"
                     /protein_id="WP_012569512.1"
                     /translation="MGALIKTGAKIIGSGAAGGLGTYIGHKILGK"
                     /name="GatB family leaderless bacteriocin"
     gene            complement(5855..5947)
                     /locus_tag="E3S92_RS13855"
     CDS             complement(5855..5947)
                     /locus_tag="E3S92_RS13855"
                     /inference="COORDINATES: protein motif:HMM:NF038165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB family leaderless bacteriocin"
                     /protein_id="WP_012569511.1"
                     /translation="MGAVAKFLGKAALGGAAGGATYAGLKKIFG"
                     /name="GatB family leaderless bacteriocin"
     gene            6307..8022
                     /locus_tag="E3S92_RS13810"
                     /old_locus_tag="E3S92_13810"
     CDS             6307..8022
                     /locus_tag="E3S92_RS13810"
                     /old_locus_tag="E3S92_13810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002445837.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000549613.1"
                     /translation="MHKSNPLLSILKNLKFPKLLLLSALIISSIGSIAGLLVPWFTGEL
                     VNKINGNSLSFNFLVIVISIFLLNAIISGVGLYLLSKIGEKIIFSIRCLVWNHIVRLKT
                     SFFDSNESGELLSRIIDDTKVINTFVSHKLPSTLPNILTIIGSIIMLFILDWKMTLCTF
                     VIVPLFFMIILPLGQMMEKTSNKTQNEIAQFSGMISRILSEIRLVKVSSTENLEVKNGK
                     DRLTNIYNLGIKQAKITSIIEPISSILVLLMIAIVLGFGGWRVSSGNISSGNLVAMIFY
                     VFQLVLPISNISTLITDYKQAKGASFRLSEILSQKTEEIEGKRNEDLDIPFIKFENVTF
                     SYDKEEILKNLSFTIPQNKVTAFVGPSGSGKSTIFNLIEKMYDIDNGKIYIGNSLLSDL
                     DLLSWRKNLGYVMQDNSMMSGTIRDNILYGLEDQEIKDDYLDYYCKLANCYDFVNNLEE
                     RYNTFIGERGVKLSGGQRQRIDIARSFIKNPKVLLLDEITANLDSESEHKIQDAMSTLM
                     RDRTTIIIAHRLSTIQKADQIIFLDNGVITGMGDHNSLYNSHKKYKEFVLNQHI"
                     /name="ABC transporter ATP-binding protein"
     Typing          4237..4474
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="96.25"
                     /coverage="100.0"
                     /evalue="9.95e-107"
     Typing          complement(805..1661)
                     /name="rep_cluster_2222"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="90.909"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2981..3861)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="91.837"
                     /coverage="87.0"
                     /evalue="1.16e-168"
ORIGIN
        1 atctgatata tacactttgt tatattgagt gatcagaata aaattaatac agtgaatact
       61 atatacgaaa caactaccca taattgaaca ttatgttaac taaaagaaaa gcccgaaaca
      121 ctgatatgaa agtgtttcgg gctttttatc aatcttagcg ggtattcatc ttttatacat
      181 taccctaaat gacacgtttt cattcttttt cataacttaa gtttttgtat ctttattcag
      241 ttacgatttc ttttctccaa cctaacaaac catctttaac tctaataata tgtctgccac
      301 gccagacact tcttacttcg aaataatacc attccccgtt tttgttgagg aaatgaatat
      361 cttgataacc ttctttaatg acatattttg tagcttcttg tctttgatcg ccaaacatca
      421 tcaatcccac ccttatatta atttatcttt aatatataac aacatttatt aatattcatg
      481 ttatttcatg gaaggagaga tttgttataa tgtgaaagtc gtctatctct cagacgtcga
      541 tttgacgtag agaggaggtg cgctaaatga cattactatt tgtttatgta atagctcctg
      601 tttttgtagg atgctgtatt acgttgtttc aattttggct agaacaacgt agtaaaaaat
      661 aggcgacaag ccaacactaa aagaaccccc aacctacgtc cataggttgg gggttcggtg
      721 cgttaatgac accactattt gttgtctaaa tagtatcatt ttattacaca ttcttcaatt
      781 attatttatc gtttaataca tttttattct tcccaattca tttcaagttg ttttaaaaag
      841 gcttctcttt ctttttctag ttgtggatca tattctcttt ggggtgtttt ttcatatgtc
      901 ctttcttcta accattttgg tgttttctca cgactgatat attgtcgtga cttacctata
      961 ttcgccattt gtggttctcg tttattgtgg atgcgtttct cagcgtcaaa agtaaactct
     1021 aaccattcaa ttttacgacc ttttttggct ttaactttat tgatattaag gttattaaag
     1081 ataaacccta attctttaat tataggagct aatacttttt gattaatatg agtcatgcga
     1141 taactattag gaatatctaa tcgttctcta aaatcttcaa tttgaatttt aaaataacct
     1201 gtgtgtttat attgttttaa taatctaaac atatttttag agtatgtaga tttaagattt
     1261 gtcatttctt ttaattcaaa tttagtaaaa tcagctgtta tttcatttaa aacatgcttt
     1321 aatttaggat taatactaac gattaaattt ttctcatcaa catcaacttc atacccagta
     1381 aataatacaa attttttgaa agatagacca cttctttcag tataagttag agttaacatt
     1441 ttatcgtata catgttctaa gtctttaaca aaacgtttta atgagcgatg atagtaatta
     1501 cttaaatgac gtaactcttc aaaagggata gctaattctt ttatatcttg ttcttttaac
     1561 ttattacaaa gactaaaaaa tatatcaatc tctgtgctgg taaacttacg taatggaact
     1621 aaattcattt cattttgata tacaacagtt tctccagaca tgtttataaa acctcctaaa
     1681 gaataagtgg attaaaagac actttattaa taataagatg tcttttaata atataagaaa
     1741 aattcaatta aaacctataa tagcataatt gtaacaataa aggcaactcg cgattaaaaa
     1801 gttgccttta ttgttacaaa aagttgcctt tattgttaca aaaagttgcc tttattgtta
     1861 caaaaagttg cctttattgt tacaaaaagt tgcctttaaa atctcaaatg cattgtccct
     1921 ctaaggttca aacaccccct aaaaagggtt ttaaaaagat ttataaaaag atattaaaaa
     1981 gttcggggca attttcccct cacaaattca agagacaaaa aggaaagcaa ccacaaaagt
     2041 ggttgctttt ttatttataa aatcaattaa gtcgttactc attgatgtat tattccaatt
     2101 gctttattga cattgagcct ctgtcccctt aacaaaccca aaaactgtcg actcatcggg
     2161 ttaatagctc acgctatacc cgacattcgt cgaaacagtt tagttaaggg gacttctcaa
     2221 cgatcaataa attttctcgg cataatagcg atatctaatc tttaatacgc ttctcataac
     2281 gatggattta aatagtcatt attatttaaa tgcttttaaa atccattttc agcttcatgt
     2341 agaacttcta tacgttgata tgattctcta cctattcaaa atgaactaac gcgcttatat
     2401 gcgcttaaaa tgccacgtat aagcaaccac aataagatat aagggattaa ataaaggata
     2461 acgataaaat aacgccatgc tgaatgacct gttttgagta catgattaat ccattcataa
     2521 aaataatgaa cacctaatac atcgcttaac ggacttaaaa ctaaacatgc gaccattact
     2581 aaagcaacga tgaaaaacat agaagttaat cctttcgtta acttattcac tgcttgatca
     2641 tactgcttta tcgcggtttc atttttgttt aagcgtgctt caatggtttt cgcgtattca
     2701 ttattggatg tttgtaattc tatctgactc acttgaaatt gtttaaccat attttctgtt
     2761 tccgatttaa tatcttttag ttcttcttgc atggctgttt tgaaatcttg ttttaaatta
     2821 tcactatcaa tgcgttgaat atagtgtttc attgcgctaa taaatcgttt ttcattagtc
     2881 tttgtcgctt gatcaaagtt cgtagccgtg gtctcgatcg ttgttaatat tttttcgtgt
     2941 cgctcgttcc gcttgaattc tctcttctcg atctcttcga gccttttcat gagcaagtct
     3001 tgctgattct gcagcttttc ggctacgctc caattcattt gtatccttgg cgaatcgatc
     3061 ccaatctgat tgagtgatgc ttgtatctct ttcagttgat tcatcacgat tcgaagttcg
     3121 tcgtttcggt tggtagtcgt gttctgagtc tcgttcttgt tgtcgtcgtt gtatttgtct
     3181 ttcaaagcca tcttctatgc cccctttatt gtaattttcg cctaatcgac gcccccgtac
     3241 ttttttatct tcagctaggt gtcgatacgt aatgcttttt ggtgtgacac gttcaatttc
     3301 aatgccatat tgacttaaat gcgtttttaa ttcgtctata ttcgttgctt gtgattggtc
     3361 gatagcttct cgaatttcat ctttccatga atactgtgct gttgatttta tgtttggatc
     3421 cgcaatggct ttttcagttt gggtataacg taagcgtgct gtatctttct ctggtacgct
     3481 taaaccatga ttgcgacaaa cttcgtcatt gaaatttctt aagtcacgta atgcttgttt
     3541 attgttgttg aatttcttac ctgtttcaag attaatacta ttaatcacaa tatgattatg
     3601 tacatgatcc gtatcattgt gtgtatagac agcgacttga tgattcggtg caaatttttc
     3661 agcgagttct aaacctagct gattacattg ttcaggtgta acttcatcag gtttaaaggc
     3721 ttgtataatg acatgacctt ggttgccatc tgttttaccg taaagctcac gagacgcttt
     3781 gaaactcgat ttagcataat ctacatcaca gtttaagcca cttttctcaa cagcgcgttt
     3841 ttcagcgtaa ttaatagcac gagatgttga tttggttgcg cttagtttag ttgttgccat
     3901 atgtcatcca gcctttcacg taattcgctg atattacgtt ctaatgcttc gtaatttggt
     3961 gcgtcatatt gatgttggtt acaatatttg gcaatttgat tggcatttga acctaattta
     4021 cctaaatcac tagctagaga ttgtcgtgta gttttatcta atttaggtac aactaatcga
     4081 gtgccttgtg cctttttctt aacgaaagca ggcacactca tatttaaagt ttcagccgat
     4141 tgtttcaact ttaaatattc ggattcgctc acacgaaaac taatttgttt tggcgcttta
     4201 cggttgggtt tatgaatttg cccattaacc gtatcgctag ccacaaatat gttttgttcg
     4261 ctcatacatc ccaccacgct ttctacgaaa gataactcct taatataaat ttactttata
     4321 ggataaagta aatttaatca agtcgttata gtggtttggc aagcattggc tttgctagcc
     4381 actaacgtgg tagcatcgcc tgcttgttgg ggatattccc caagcccctt aggatttttt
     4441 ctggcgaaaa aatagtggct aattgctagc cactattaat ataaatgtat ttaaagatgt
     4501 ttagcttttt ttcttgatat cggtaaaaat aattcttaca agaatactaa ttactgaaat
     4561 gtttaatatt tcaaaaaata taaatttgat ttcagaaata aggttaagta agaaaaaaca
     4621 atgatatata gcgaggaagt tcctgcagta tacattgatg aaaaaattag acaccccata
     4681 ttcttataaa gaatacaaaa aatacttgaa gcaaacaaat aaattatata ttttacccat
     4741 aatcaaacat tagtttataa acaccctaaa tacttacgtt tataatacgt tttaattttc
     4801 aaggtaatct cattttaact ttataatgac gagggtattg cataattaat atagatttgt
     4861 tacattataa atgcaatata tatatggcaa aagtgtgtgt gaaaaaggaa gagtttataa
     4921 tcatgataaa taatattaag cattatcgta aagaaatgaa tttttcgcag caagagttgg
     4981 ctaataaagt tgaagtaaca aggcagacaa tatctttaat tgaattaggg aaatataatc
     5041 ctactatcaa attatgtatt agcatagcta aagctttaca agtagatttg aataaattat
     5101 tttgggaaat gagtgataat agtgaggaat aatagaaata tggatgaaag acaagaaata
     5161 attaataaga atatgttaat taggtctttt ggctttttat ttatactatt aataatttat
     5221 atagcttttt taggcgtgat taatgtaact ataacaggac accaattaat attaatcagt
     5281 attattacac taactagtat atatatgtgg attgattctt ttataaataa aattttgtat
     5341 tatgatgttc aaaataacaa agagataaaa cgaaagttgt catcatgcgt tacgacattg
     5401 ttagttattg atgttgcagt tttaatattg gcttttttaa ataagattga tattaatatt
     5461 tcatttttat ttttagctat attaatatcc tttaacatta tagtactaag tgtatattat
     5521 ataatattaa aattctggtt aatttggtat aaatagaaaa atcgagtatg aggtttgatt
     5581 aaaccttata ctcgaatgct tagttatttt ttaaaaattt tttctaaacc atataaacct
     5641 gcgccactag cggctcccca accaatgacc ttagcaccta ctttaattac tgcgcccata
     5701 gttttctctc ctttgctttt taagtaaacg ctatttacct agaattttat gaccaatata
     5761 tgtacctaaa ccaccagcag caccactacc aatgatttta gcaccagttt taattaatgc
     5821 acccatgtaa ataactcctt aaatttttta aatattaacc aaaaatcttt tttaaccctg
     5881 cgtaagttgc gccaccagca gcaccaccta aagctgcttt accaagaaat tttgctacag
     5941 cacccatgaa aacacctcct cgaaaattat ttatagaatt atttacctac agctttctct
     6001 ccagcagccc aaccaagagc gctagcgata ccaccgccaa tgatttttcc agctttgata
     6061 gctaatttcc ccattgtaac acctcccttt tttctcttgt taatatttta ttattagttt
     6121 gttttaatat caagatattt attaataaaa taattaggta ttgtaaaaac tatatattga
     6181 tattattatt atacataact atcattatgt attttcaaat aatttatgat aaagcatatg
     6241 ttgctatggg tttattcggt ttaagtaaca tgtgctttta attttgtaat tataggagtg
     6301 actaatttgc ataagagtaa cccattatta agtattttga agaacttaaa gtttcctaaa
     6361 cttctattat tatcagcttt aattatatcg tctattggta gtattgctgg tctattagta
     6421 ccatggttta caggggaatt agtaaataaa ataaatggaa attcactaag ttttaatttt
     6481 ttagttatag ttatttctat atttttatta aacgcaatta taagtggtgt tggtttatat
     6541 ttattaagta aaattggtga aaaaatcatt ttttcaatta gatgtttagt atggaatcat
     6601 attgttcgat taaaaacttc tttttttgat tcaaatgaaa gtggagagct attaagtaga
     6661 ataatagatg atacaaaagt aataaatact tttgtatcac acaaacttcc tagcacttta
     6721 cctaatatat taacaattat tggatcgata attatgcttt ttatattaga ttggaaaatg
     6781 actctatgca catttgttat tgttccttta ttttttatga ttatactgcc tttaggacaa
     6841 atgatggaaa aaacttctaa taaaacacaa aatgaaattg ctcaatttag tggaatgata
     6901 agtagaattt tatcggaaat tagattagtt aaagtttcaa gtacagaaaa tttagaagtc
     6961 aaaaatggta aggatcgatt aactaatatt tataatttag gaataaagca ggctaaaata
     7021 acatctataa tagaacctat atcgagcatt ttagttttat tgatgatagc tattgtcttg
     7081 gggtttggag gctggagagt atcaagtggg aatatatcat cgggaaattt agtagcaatg
     7141 attttttatg tatttcaatt agttttacct attagtaata tttcaacact aataactgat
     7201 tataaacaag ctaagggagc tagctttagg ctatcagaaa tattaagtca aaaaaccgaa
     7261 gaaatagaag gtaaaagaaa tgaagattta gatatacctt ttattaaatt tgaaaatgtt
     7321 actttttcat atgacaagga agaaatattg aaaaatttaa gttttacaat accacaaaat
     7381 aaagtgacag cttttgttgg accttcagga tctggaaaaa gtactatatt caatttgatt
     7441 gagaaaatgt atgacattga taatggaaaa atatatatag gtaattcatt attgagtgat
     7501 ttggatttat tgagttggag aaaaaatcta ggatatgtaa tgcaagataa ctcaatgatg
     7561 agtggcacta tacgagataa tattttatac ggattagaag atcaagaaat taaagatgat
     7621 tatctagatt attactgtaa attagcaaat tgttatgatt ttgttaataa tttagaagaa
     7681 aggtataata catttattgg agaaagagga gtcaagttat ctggagggca acgccaaaga
     7741 atagatattg ctagaagttt tataaaaaac cctaaagtac tattacttga tgaaattact
     7801 gcaaatttag atagtgaaag tgaacataaa attcaagatg caatgtctac tttaatgaga
     7861 gatagaacaa caattattat tgcacatagg ctatcaacaa tccaaaaggc tgatcagata
     7921 atatttttag ataacggtgt aatcacaggt atgggggacc ataattcatt atataacagt
     7981 cataaaaagt ataaagagtt tgtgttaaac cagcatatat aacaaagtgt atat
//
