LOCUS       NZ_CP047718            15459 bp    DNA     circular CON 15-APR-2024
DEFINITION  Enterobacter hormaechei strain Eho-E2 plasmid pEclE2-3, complete
            sequence.
ACCESSION   NZ_CP047718
VERSION     NZ_CP047718.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN13747519
            Assembly: GCF_015910205.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter hormaechei
  ORGANISM  Enterobacter hormaechei
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 15459)
  AUTHORS   Kohler,P., Tijet,N., Kim,H.C., Johnstone,J., Edge,T., Patel,S.N.,
            Seah,C., Willey,B., Coleman,B., Green,K., Armstrong,I., Katz,K.,
            Muller,M.P., Powis,J., Poutanen,S.M., Richardson,D., Sarabia,A.,
            Simor,A., McGeer,A. and Melano,R.G.
  CONSRTM   Toronto Invasive Bacterial Diseases Network (TIBDN)
  TITLE     Dissemination of Verona Integron-encoded Metallo-beta-lactamase
            among clinical and environmental Enterobacteriaceae isolates in
            Ontario, Canada
  JOURNAL   Sci Rep 10 (1), 18580 (2020)
   PUBMED   33122675
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15459)
  AUTHORS   Melano,R.G., Tijet,N. and Seah,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2020) Research, Public Health Ontario, 661
            University Avenue, Toronto, Ontario M5G 1M1, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v 0.4.8-BETA
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology :: Illumina MiSeq, Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015910205.1-RS_2024_04_14
            Annotation Date                   :: 04/14/2024 21:08:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,878
            CDSs (total)                      :: 4,764
            Genes (coding)                    :: 4,647
            CDSs (with protein)               :: 4,647
            Genes (RNA)                       :: 114
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 32 of 117
            Pseudo Genes (incomplete)         :: 81 of 117
            Pseudo Genes (internal stop)      :: 23 of 117
            Pseudo Genes (multiple problems)  :: 17 of 117
            Pseudo Genes (short protein)      :: 1 of 117
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047718.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..15459
                     /organism="Enterobacter hormaechei"
                     /mol_type="genomic DNA"
                     /strain="Eho-E2"
                     /isolation_source="Sewage water"
                     /db_xref="taxon:158836"
                     /plasmid="pEclE2-3"
                     /geo_loc_name="Canada:Ontario"
                     /lat_lon="43.6532 N 79.3832 W"
                     /collection_date="2015-07-23"
                     /collected_by="Public Health Ontario"
     gene            join(13639..15459,1..1069)
                     /locus_tag="GVI74_RS24135"
                     /old_locus_tag="GVI74_24075"
                     /pseudo=""
     CDS             join(13639..15459,1..1069)
                     /locus_tag="GVI74_RS24135"
                     /old_locus_tag="GVI74_24075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            complement(1534..1656)
                     /locus_tag="GVI74_RS24510"
     CDS             complement(1534..1656)
                     /locus_tag="GVI74_RS24510"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_258364704.1"
                     /translation="MQITYRLTTAAHQLQIRVSLTQIAAAALAALGWWHGLPLF"
                     /name="hypothetical protein"
     gene            complement(2409..2696)
                     /locus_tag="GVI74_RS24140"
                     /old_locus_tag="GVI74_24080"
     CDS             complement(2409..2696)
                     /locus_tag="GVI74_RS24140"
                     /old_locus_tag="GVI74_24080"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_045284286.1"
                     /translation="MSIVLEQDGSHGVALHDAGEGQQFTGPGLGAGALRSGRYWVQSPM
                     TPYAQPQLWGTYTDDLERAQNAYRVEVARCKAQKEAREYVARHYPRKPRN"
                     /name="hypothetical protein"
     gene            complement(3120..3461)
                     /locus_tag="GVI74_RS24145"
                     /old_locus_tag="GVI74_24085"
     CDS             complement(3120..3461)
                     /locus_tag="GVI74_RS24145"
                     /old_locus_tag="GVI74_24085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010256658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_045284288.1"
                     /translation="MINVMKVNGHAATVAFDPEIEMFRGSFVGLTGGADFYARTVEELH
                     REGAESLRFYLEICEKRGIEPYKAYSGKVSTRLTPERHQALEQIAAAHGESINQLLNEG
                     ADLVIERYA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            complement(3458..3721)
                     /locus_tag="GVI74_RS24150"
                     /old_locus_tag="GVI74_24090"
     CDS             complement(3458..3721)
                     /locus_tag="GVI74_RS24150"
                     /old_locus_tag="GVI74_24090"
                     /inference="COORDINATES: protein motif:HMM:NF019540.4"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_045284289.1"
                     /translation="MTLRKQHQRTLEAIYRRPVSGTIEYKDFKALMLALGAELDESAAG
                     SREGFTLRGEPRVFHRPHPKSTMDKGAVSEARQWLERLGIKP"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            complement(3857..4171)
                     /locus_tag="GVI74_RS24155"
                     /old_locus_tag="GVI74_24095"
     CDS             complement(3857..4171)
                     /locus_tag="GVI74_RS24155"
                     /old_locus_tag="GVI74_24095"
                     /inference="COORDINATES: protein motif:HMM:NF012651.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_052686900.1"
                     /translation="MTAHMSAHGRLIADPTHKITDSGTALAMGRLVVSLPCHTAEDGAA
                     PLWLGVVCFGKVADTLKRCRKGDVISISGAMQISQWRGQDGHPTERRECGRGHCGACQS
                     "
                     /name="single-stranded DNA-binding protein"
     gene            complement(4267..7122)
                     /locus_tag="GVI74_RS24160"
                     /old_locus_tag="GVI74_24100"
     CDS             complement(4267..7122)
                     /locus_tag="GVI74_RS24160"
                     /old_locus_tag="GVI74_24100"
                     /inference="COORDINATES: protein motif:HMM:NF017116.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="WP_045284290.1"
                     /translation="MNEQNREALIEAWRNPLRDELTRKGYRIAPARDNGTDPDTGKRQV
                     KAAPFAKGENYGPKHTRWAAKNTLADAVALVLGPRVVCLDYDANKPGTISEAELRERVP
                     ELPANPHQLRESDGSAHYFFQMPQGAPLGRIKQNNVNAMGLQGVDVLTGNQVIYLKADK
                     VQDFPPVEELPTLPAAVLAAMTRPEIPQETAYEPTDREEGSRYVIGALKLAIEAIRATE
                     SGRNNKLYSEARNLFRYAEGGYIDHKFVREALHVHGLAIGLAITEVTDTLKSAQDAARQ
                     DGPKHPKPSKKAERATLNGKKPAYQGGDVHATRPAAEPAQTTSPDQRTTGTDTSEKNQP
                     ETAGARLNAGTPNETLKGPNVADYEEMKPEIRAAVEHTARQTGKDSAEILRWLNERGES
                     AFMGFYLAQPWAKKTKGPEAESKAQQQAPAAPQEPQEEPEPATVEPGGKEAPQVVTGEL
                     ITAAQMQGRKVHHDDGMTNEGIASFLVASAGEKYAPFSAWCGLTGNEERDHNRGLIATA
                     IRRHVRNIPPVVEAVRNKDGDITRFTSANHRDNYFWMCYRYGITVARNLLTFDFEAFDS
                     RTNRRLTADEEMTLSDLIGHAAEQKLPPNLVASHMSAAAKYTEYHPISQLLHGKTWDGV
                     QRVQRVIDCVPVKAEDEAHRNQLLTGIFLAAITALDEGSVSIKYVPVLYSKENDFYKTH
                     FIKRIFDIMDGAFKEGVSIDPSHKDSVRKAVYCWGAELGELDSMTKKESGPLKAFIPLD
                     VDEWRTEGVKTYIKKPRQTVFMGSVNKPKFLKDETMASRFPVIALTAPIKIDAVNQILG
                     WRMRKDGPELVKRDDLIQFWLEVRAMRAAGATHVLDRDFLADMKGRNDQYIDRGGLRDS
                     IVEAIEQHRTKGTGNPFTVDQRGDKFTVSEVARHFNIKIEGDKSEQIGKTLTRMAQDEE
                     LLIKRRTGRGYYYMINWPAFD"
                     /name="VapE domain-containing protein"
     gene            complement(7133..7423)
                     /locus_tag="GVI74_RS24165"
                     /old_locus_tag="GVI74_24105"
     CDS             complement(7133..7423)
                     /locus_tag="GVI74_RS24165"
                     /old_locus_tag="GVI74_24105"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_045289091.1"
                     /translation="MTNNRPAGMPQDHITALEFSLLLAVSHTTFAALRKRADFPQAHPA
                     PRKAITFNHDEALAFALAWNEEQAKRYHGKMTADRFIEQAARIKSLTATQR"
                     /name="hypothetical protein"
     gene            complement(<8617..8811)
                     /locus_tag="GVI74_RS24485"
                     /old_locus_tag="GVI74_24110"
                     /pseudo=""
     CDS             complement(<8617..8811)
                     /locus_tag="GVI74_RS24485"
                     /old_locus_tag="GVI74_24110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004785028.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            9067..9300
                     /locus_tag="GVI74_RS24170"
                     /old_locus_tag="GVI74_24115"
     CDS             9067..9300
                     /locus_tag="GVI74_RS24170"
                     /old_locus_tag="GVI74_24115"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_045284284.1"
                     /translation="MQAAIAWEHAEEAALVAFLNAEDEDRAFREQVAANEQDLEQEPEI
                     IDDHGGLTFDEWLAGGRSAYEAQQADDYSFFR"
                     /name="hypothetical protein"
     gene            9354..9749
                     /locus_tag="GVI74_RS24175"
                     /old_locus_tag="GVI74_24120"
     CDS             9354..9749
                     /locus_tag="GVI74_RS24175"
                     /old_locus_tag="GVI74_24120"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_045284283.1"
                     /translation="MTLTAIFAGAAAVIGLAFAYRLYETRNDAQQDEPKAPPAPAAVKP
                     VQPQPPRRKKRLWAAPLAVFIAAEVALHMLIATGGCADGWHSASIGRAGACSYHGGVNH
                     SGGFILLISLALAGYTFYQVTKDRTKK"
                     /name="hypothetical protein"
     gene            9798..10136
                     /locus_tag="GVI74_RS24180"
                     /old_locus_tag="GVI74_24125"
     CDS             9798..10136
                     /locus_tag="GVI74_RS24180"
                     /old_locus_tag="GVI74_24125"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_045284282.1"
                     /translation="MKHAPLIGRLLALALTMTAGSAAATTGDRMFEAQQHGIANICEKS
                     ANPAECAAAVNVLLVGTANQITTATLCELGEPANAAEARKCEAAKQYRDRLDAAGHQAA
                     AELGMSSH"
                     /name="hypothetical protein"
     gene            10284..10442
                     /locus_tag="GVI74_RS24185"
                     /old_locus_tag="GVI74_24130"
     CDS             10284..10442
                     /locus_tag="GVI74_RS24185"
                     /old_locus_tag="GVI74_24130"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_157843638.1"
                     /translation="MAIGMLEATENLFNSICSNTTDPKGCLAGLTQILEEAHKDGMLVG
                     VVSENGK"
                     /name="hypothetical protein"
     gene            complement(10449..11006)
                     /locus_tag="GVI74_RS24190"
                     /old_locus_tag="GVI74_24135"
     CDS             complement(10449..11006)
                     /locus_tag="GVI74_RS24190"
                     /old_locus_tag="GVI74_24135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019897068.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_003100847.1"
                     /translation="MLIGYARVSTQDQNLELQREALSKAGCKKVFEDKVSGTRADRPGL
                     AKTLEMLREGDTLVVWKLDRLGRSVKQLVDLVGDLHKHGVQFRSLTDSIDTGTPSGRFF
                     FHVMASLAEMERELTVERTRAGLEVAKQLGRKGGRKPKMTDSKIESAKKLLASGVPPKD
                     VAKNLGVSIPTLYRWVPASTHA"
                     /name="recombinase family protein"
     gene            complement(11000..11371)
                     /locus_tag="GVI74_RS24195"
                     /old_locus_tag="GVI74_24140"
     CDS             complement(11000..11371)
                     /locus_tag="GVI74_RS24195"
                     /old_locus_tag="GVI74_24140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_003100853.1"
                     /translation="MSTSTIEALASAWARIAEEAEFPADYEGTATPQAHRASEAIQEQI
                     RERIVATNDMRLFSLLHLLGQASLRMEQALWPEDYERMTREVEEALRQATDANARSYTH
                     EEVMQAMQERIDRARDKPC"
                     /name="hypothetical protein"
     gene            complement(11368..11868)
                     /locus_tag="GVI74_RS24200"
                     /old_locus_tag="GVI74_24145"
     CDS             complement(11368..11868)
                     /locus_tag="GVI74_RS24200"
                     /old_locus_tag="GVI74_24145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_003100856.1"
                     /translation="MKLSFHQHIALFWMIGAPGVFAPVIENAKRPDAGAVMAWGVAIVA
                     VMILFTPLLLRCPPFRRWYGRTDALSERQRQALAERGLRRYYQTAFDDGYVPRVMPYVW
                     RIIWTVGGLMAVTAVLPTNTGRPAFDALVVFSTWYPIGVMLLVFASRPLGRLIRQRAQE
                     RRK"
                     /name="hypothetical protein"
     gene            complement(11865..12191)
                     /locus_tag="GVI74_RS24205"
                     /old_locus_tag="GVI74_24150"
     CDS             complement(11865..12191)
                     /locus_tag="GVI74_RS24205"
                     /old_locus_tag="GVI74_24150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011809177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_003100858.1"
                     /translation="MSRSRRKTPIVGHTTCGSEREDKKLWHQRWRTRERTALTSASPEA
                     LSAHLPLLENQASSVWSMGKDGRSYWPVKRQAATADRIANHKGRNPQERASLKKRLLRK
                     WMSK"
                     /name="hypothetical protein"
     gene            complement(12446..12802)
                     /locus_tag="GVI74_RS24210"
                     /old_locus_tag="GVI74_24155"
     CDS             complement(12446..12802)
                     /locus_tag="GVI74_RS24210"
                     /old_locus_tag="GVI74_24155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003465043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="WP_000215515.1"
                     /translation="MTVESRIFSVAEYVQPSEGEPIRSVVLETRDSIIVVWHVHPGQEI
                     AAHIHPHGQDTWTVLSGMADYFQGNGIVRALREGEIAVARPGQVHGARNTGTEPFVLVS
                     VVASANAGFVLAER"
                     /name="cupin domain-containing protein"
     gene            complement(12792..13193)
                     /locus_tag="GVI74_RS24215"
                     /old_locus_tag="GVI74_24160"
     CDS             complement(12792..13193)
                     /locus_tag="GVI74_RS24215"
                     /old_locus_tag="GVI74_24160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF86 domain-containing protein"
                     /protein_id="WP_001293886.1"
                     /translation="MSENRLPDYLDHIQQAATDARSFVEGMAKDDFLADKRTQQAVIMS
                     LIVIGEAATKVMDGYVEFTQAHADVPWRSMRNMRNRMAHGYFDINLDVVWETVQEWLPA
                     LLQQLPAVRQDADDEDRNDNCERGISDDC"
                     /name="DUF86 domain-containing protein"
     gene            complement(13190..13480)
                     /locus_tag="GVI74_RS24220"
                     /old_locus_tag="GVI74_24165"
     CDS             complement(13190..13480)
                     /locus_tag="GVI74_RS24220"
                     /old_locus_tag="GVI74_24165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="WP_001247892.1"
                     /translation="MRPSVVLDMKRSAVREAVGRFRAANPRVFGSVLHGTDRDGSDLDL
                     LVDALPGATLLDLGDLEEELKSLLGVDVDLLTPGDLPPKFRAKVLAEAQPI"
                     /name="nucleotidyltransferase"
ORIGIN
        1 aacctgttgc tgaccacgat cctcgccgac gcgatcaacc tgggcctgac caagatggcg
       61 gaatcgtgcc ccggcacgac ctacgccaag ctggcctggc tgcaagcctg gcacatccgc
      121 gacgaaacct acggggcggc actggccgag ctggtcaacg cgcagttccg acatcccttc
      181 gccgggcatt ggggcgacgg caccacgtca tcgtcggacg gccagaactt ccgcaccggc
      241 agcaaggccg agagcaccgg ccacatcaat ccgaaatacg gcagcagccc agggcggacg
      301 ttctacaccc atatctccga ccagtacgcg ccgttccaca ccaaggtcgt gaacgtcggc
      361 gtgcgcgact cgacctacgt gctcgacggc ctgctgtatc acgaatccga cctgcggatc
      421 gaggagcact acaccgacac ggcagggttc acggaccacg tcttcgcgtt gatgcacctg
      481 ctgggcttcc gcttcgcccc gcgcattcgt gacctgggcg acaccaagct ctacatcccg
      541 aagggcgatg ccacctacga ggcgttgaaa ccgatgatcg gcggcacgct caacatcaag
      601 cacgtccgcg cccattggga tgaaatcctg cggatggcca cctcgatcaa gcagggcacg
      661 gcgacggcct cgctgatgct caggaagctt ggcagctacc cgcgccagaa cggcctggcc
      721 gtcgccctgc gtgagctggg acgcatcgag cgcacactgt tcatcctgga ctggctgcaa
      781 agcgtcgagc tgcgccgccg cgtgcatgcc gggctgaaca aaggcgaggc gcgcaacgcg
      841 ctggcccgcg ccgtgttctt caaccgcctg ggggaaatcc gcgaccgcag cttcgagcag
      901 cagcgctacc gggccagcgg cctcaacctg gtgacggcgg ccatcgtgct atggaacacg
      961 gtctatctgg agcgggccgc gaacgccttg cgtggttcga acaaggcggc cagctctccg
     1021 gggtcgatca tttgattggc tctggcaatc aaggcggcta gggcgttagc tcgtcgctga
     1081 atacttccgg ccagtgctcg gccagctcgt cgtaatagca gatctgcggg tgggttatgc
     1141 tgtcgcggat agactttatc agggctttag ctgttcgggt gtctgctggc gctcatgcgc
     1201 tttaactcca gctcggccgc gtctcttcgg tctggtgcgc tggggcgttc gtctcggcca
     1261 ataagttacc ggccgttggt gatctcgtcc aggggttcgg cctgctggtg gaatgtttca
     1321 gacaaccgcc aggatctggc tttagctggc attgtttatg ccagctcggc ggcatagctg
     1381 gcactatcag cccagcatgt ggccgcgttc tcgtcgtttc ctcctcgtag taacggtgtg
     1441 tgattggttt ctatgtgctg cataacctgc cgcccgtttt ctcctcgttg tggcgggttg
     1501 cggggtaggt cagtaaatcc ccgtcattct ccgtcaaaat aacggcaatc catgccacca
     1561 gcccagggcg gccagcgcgg ccgctgctat ctgggtgagg cttacgcgga tctgtagctg
     1621 gtgcgcggcg gtggtcaatc ggtaggtaat ctgcatattt cgtactccgt gggttcgttc
     1681 gtgttctaag gggttcacat tcagccggtg atcgcccttc ccctttcaac taatgcccca
     1741 gatctgcgcc ggtgccgcac atttgcaccg ctcatacacg catacgtgag gacgtgcgca
     1801 cggttggcgc tctcgatcct cccttccctc tctctgcctg caaaggtcaa aacatggctt
     1861 atcagggggg cgtttcttct ggcccgttgc tgctctgttg ctccctcatt gcctgcctgg
     1921 tctttgggtt ctccgggggt gaagatctgc gccggatctt tcaggctagc tggatgttgt
     1981 aactaatgcg tgtaggggtt gtgtaggtat ggtgtaggtg taggggtaca tacacgccac
     2041 atacacgggg ccatacacaa tcgaactttc cagcattggc ggggcttggc ggggtgtttt
     2101 gcctggtttg gtgtaggtgt gtaggtattt tatccctacc gtatatatat agcggatctc
     2161 tcttttctgt tttttgctca cgtatagcta tattttacat acatacatac actaaaggtt
     2221 ataaaaggca atgaaatcag gatgttaagt ttggtgtatg gggggggtgt atgtatggtg
     2281 tatgtgaatc cacatacact aaccacatac actaattgcg caccttttga cctctggccg
     2341 gatctcctcc cggatcgtgg gtacaaaaaa gcccgcgcaa tggcgggccg ggtgtatgta
     2401 tggggggatc agtttcgggg cttgcggggg tagtggcggg ctacatactc ccgcgcctct
     2461 ttctgcgcct tgcatcgtgc cacctctacg cggtaggcgt tctgcgcccg ctccaggtcg
     2521 tcggtatacg ttccccatag ctgcggctgc gcgtatgggg tcatggggga ttgtacccaa
     2581 tagcgcccgc tgcggagtgc cccagctccc agccccggcc cggtaaactg ctggccctct
     2641 cctgcgtcgt gcaatgcgac gccgtgcgat ccgtcctgtt ctaaaactat gctcattcta
     2701 tcttgtcctc tctgttcact tcctcgcgta gctgctgcac cgtctcaagg ggtagggctg
     2761 taatccgctc tatggtcttg ttatccagcc ccagacggat cagcgctttg gcctgcggcc
     2821 gtgcgtgtgg tggtggtttc ctgtcgtctc gtcggttgcc ggtgatagga tttatcacaa
     2881 tatcccccac gcgtagggct gcgggcttca ctgtctgccg tatcatgtcc agcgcggcgc
     2941 gttctgcgtc tccgtccagt gtaagcaggg cattaacaac ggttggccgt ctcttgccgt
     3001 gtgctgctgc cggtgtctct atttcggtgc ttgcttcgtc tcctgctcct gatcttttcc
     3061 tcctgtttag gccataaaaa agcccagcat tagccgggct tgatgtgtcg cgtaaatgct
     3121 tacgcgtaac gttcgataac cagatccgcg ccctcgttta aaagctggtt aatgctttcg
     3181 ccgtgggctg ctgcgatctg ctctaacgcc tggtgacgct ccggcgttaa acgggtgcta
     3241 accttgccgc tataggcttt atacggctcg atcccgcgct tctcgcagat ctccagataa
     3301 aagcgcaaag attccgcgcc ctcgcggtgt aactcttcaa ccgtgcgggc atagaaatct
     3361 gcgccgccag tcaggccgac aaagctacct cgaaacattt cgatctcagg gtcaaaagcc
     3421 acggttgcgg cgtggccgtt gactttcatc acattaatca tggtttgatc cccaatctct
     3481 ctaaccattg gcgggcttca cttactgcgc ccttatccat cgtgctttta gggtgcgggc
     3541 ggtgaaacac tcgcggctct ccccgtaacg taaaaccttc tcgcgatcct gctgcgcttt
     3601 cgtcaagctc tgcgcccagc gccagcatta aggctttaaa atccttgtat tcaatcgtgc
     3661 cactaaccgg gcgtcgataa atagcctcta gggttcgttg gtgttgcttt cttagtgtca
     3721 tagttttttc tcacggggtg atttaatggt atcaactttt gataccattg caatgttatt
     3781 accaacgtta acagcacaaa aaagcggcca cctctgcggc cgcgtttccc gttagtgggt
     3841 cactcgctcg atcttttcag ctctgacaag ctccacaatg gccccggcca cattctcggc
     3901 gttctgttgg atggccgtct tgccctctcc actggctgat ctgcattgcg ccgctgatgc
     3961 ttatcacgtc gcctttccgg catcgtttca gggtgtcggc cactttgcca aaacagacca
     4021 cgcccagcca tagcggggcg gccccatcct ctgcggtgtg gcatggcaag ctaacgacaa
     4081 ggcggcccat tgctagggcg gtgccgctgt cggtgatctt gtgggtaggg tcggctatca
     4141 ggcggccgtg tgcgctcatg tgtgcggtca taaattcgtc tcctcgctcc gggcggtttt
     4201 cgggctatgt gagtgcgtta atttgtctgg ggttgcccgg attgctccgg gcttctggtt
     4261 ggtctgttag tcgaaagcgg gccagttaat catgtagtaa tagccccggc cggtgcggcg
     4321 tttgattaac aattcctcat cctgcgccat gcgggtaagg gtcttgccga tctgctcgct
     4381 cttgtcgcct tcgatcttga tgttgaaatg tcgcgccact tccgacacgg tgaatttatc
     4441 cccgcgttgg tcaacggtga acgggttccc ggtgcctttc gtgcggtgct gctcgatcgc
     4501 ctcaacgata gaatcacgta ggccgccccg gtcaatgtac tgatcgttac gccctttcat
     4561 gtcggccagg aaatcgcgat caagtacgtg cgtagcgcct gcggctcgca tagctcgcac
     4621 ctctaaccag aattggatca ggtcgtcgcg cttcaccagc tccgggccgt ctttcctcat
     4681 gcgccagcct aagatctggt ttactgcgtc aatcttgatc ggcgcggtta aggcaatgac
     4741 cggaaagcgg ctagccatag tctcgtcttt caggaattta ggcttgttaa cgctacccat
     4801 aaacaccgtt tgacggggtt tcttgatgta ggtttttacg ccctccgttc gccactcgtc
     4861 cacgtccagg gggataaatg cctttaacgg gcctgattct tttttagtca tagaatccag
     4921 ctcgcccagc tccgcgcccc agcaataaac ggctttcctc acgctgtctt tgtggctcgg
     4981 atcgatgctc acgccctctt taaaagcgcc gtccatgatg tcgaaaatac gctttatgaa
     5041 atgcgttttg taaaagtcgt tttctttgga atacagcacg ggcacgtatt taatgcttac
     5101 gctgccctcg tccagcgcgg tgatcgcggc aagaaaaatc ccggttaaaa gctggttcct
     5161 gtgcgcctcg tcctcggctt tcaccggtac gcaatcaata acgcgctgta cacgctgcac
     5221 gccgtcccag gtcttgccgt gcaatagctg gctgatcggg tggtactcgg tgtatttcgc
     5281 ggccgcgctc atgtgtgagg ctaccaggtt tggcggtaac ttctgctccg ctgcgtgccc
     5341 gataaggtca ctcagggtca tttcttcgtc tgcggttaaa cggcggttcg tgcgcgagtc
     5401 gaaagcctca aaatcaaagg tcagaaggtt acgcgcaacg gtgatcccgt accggtagca
     5461 catccagaaa taattatccc tgtggttcgc gctggtgaat cgggttatat cgccgtcttt
     5521 gttccgcacg gcttcaacca cgggcgggat gttgcgtaca tgcctacgga tcgcggtggc
     5581 gattagcccc cggttgtggt cgcgttcttc gttgccggta agcccgcacc aggcgctaaa
     5641 cggcgcgtac ttctcgcccg cgctggctac caggaaagat gcgatcccct cgttggtcat
     5701 gccgtcgtca tggtgaactt tgcggccctg catctgggcg gcggtgatca gctcgccggt
     5761 gactacctgc ggcgcttctt tccccccagg ctcaacggtt gccggttctg gctcctcctg
     5821 cggctcctgc ggcgctgcgg gtgcctgctg ctgcgctttg ctctccgctt ccgggccttt
     5881 cgtttttttg gcccacggct gcgcaaggta aaaccccata aacgcgcttt cgccgcgctc
     5941 gttaagccag cgcaagatct cggcgctgtc tttgccggtc tgtcgtgcgg tgtgctctac
     6001 cgctgcacgg atctccggct tcatttcctc ataatctgcc acgttcggcc ccttcaaagt
     6061 ctcgttaggt gttccagcgt tcaggcgtgc gcctgctgtc tccggttggt tcttctcgct
     6121 ggtatctgtt cctgtagttc tttggtcggg gctggtggtc tgcgccggtt ctgcggccgg
     6181 tcgcgtggcg tgaacgtcgc ccccctgata agccggtttt ttgccgttca gggttgcgcg
     6241 ttctgctttc ttactcggtt tcggatgttt cggaccgtcc tgcctggctg catcctgggc
     6301 gcttttcagc gtgtcggtta cttccgtgat agccagaccg atcgccaggc cgtgaacgtg
     6361 taacgcttcg cgcacgaatt tgtgatcgat atagccgccc tcagcgtagc ggaatagatt
     6421 ccgggcttcg ctgtatagct tgttattcct gccgctttcg gttgcgcgta tggcttcgat
     6481 cgccagtttc agcgccccta taacgtagcg gctcccctct tcgcggtcgg tcggttcgta
     6541 tgcggtttcc tgggggatct ccgggcgcgt catggcggcc agtacggcgg ccggtaaggt
     6601 tggcaattct tccaccggtg ggaagtcctg caccttgtcg gctttcagat agataacttg
     6661 gttccccgtc agcacgtcca cgccttgcaa gcccatagcg ttgacgttgt tttgcttgat
     6721 gcggcccagg ggtgcgcctt gcggcatctg aaagaaatag tgtgcgctgc cgtcgctttc
     6781 gcgtagctgg tggggattgg ccggtagctc tggcactcgt tcgcgtaact cggcctcgct
     6841 gatggttccg ggcttgttcg cgtcgtaatc caggcaaacg acacgcgggc ctaacaccag
     6901 cgccacggca tcggctaacg tgtttttagc cgcccatcgg gtatgttttg ggccgtagtt
     6961 ctcgccctta gcaaacgggg ccgcctttac ctggcgtttg ccggtgtccg ggtcggttcc
     7021 gttgtcgcgt gctggcgcga tgcggtagcc cttgcgggtc agctcgtcgc gtagggggtt
     7081 gcgccacgcc tcgatcagcg cttcgcggtt ctgttcgttc attgctggcc ccttagcgct
     7141 gcgtagcggt cagggattta atgcgggcgg cctgctcaat gaatcgatcg gccgtcattt
     7201 tcccgtggta gcgcttggcc tgctcctcgt tccatgctag ggcaaaggct aacgcctcgt
     7261 catggttgaa cgtgatcgcc ttgcgcggtg ccgggtgggc ctgcgggaag tctgcacgct
     7321 tgcggagtgc tgcaaaggtg gtatgtgata ccgccagcaa aagcgaaaat tcaagcgcgg
     7381 tgatgtggtc ttgtggcatt cctgccggtc ggttgttcgt catggtcatg gccctttgaa
     7441 atcattttca aatgccacga aaaaaacgct ggttaggggc tgtgatggtg ctaaagtgtc
     7501 ttgcgcaagt agttaacgct tgacttcctg atcgcccatc gtacactttg aatagttcat
     7561 tgattcgtga tgtcacgaat gagtgagcgc ccttcctaat tttattcgtg gtgccccctg
     7621 gttggtttct gtttggcgac gtagccagcc aaggggtttc tctcgatccg ttctacggct
     7681 ttcaccggtt cgaatcattt gatcatcttg gcactattgg cgtgcatgat caagccgtct
     7741 cgcgcttaat cttttctctc atattcactc gttaatcagg tagttaacgc tttcgtgatg
     7801 ttctcccgca cctcaaaaat actatatcta ggccgccaga ctgctaaccc tctgttatgg
     7861 ctatagatcc cctttttggg gctgcttata ccatttattt ttaatcactc cgggccgctg
     7921 ctggctttta aggatttttt ttcacttttg cctgtgctgg tcactactcc ggccggtggc
     7981 cgtaactgat cctcccaggt gatgcgcctc tttgccgttc gtgctagtcg ggcctctccc
     8041 ggccaccagc tcggcggcgt gatgttaatt acttagttac atcatactaa agtgaagggc
     8101 taggggtgcc gttctgcggc tcctgtgcgc ttctcagggc ttcgcaagcc tccgggcgga
     8161 tgtttgcctg ggtggatcgg ttttatcccg tctggggggt aactggtgcg tgaattgcgg
     8221 ggttgtggtg ctggcaggta gaatccgggc ggtttttcgc gctgttctgc gcgcttccgt
     8281 tcgtaattat gatctgtcta cttgaaagcg ccgcccgtgg tgttactctc tgcggtgatc
     8341 ttttccctct ctcttgggtg aaggttggtt gtcgattctg cgcgggttgt ctccccgcca
     8401 gtgtcaccga taccgtgcgg acgtctcccg ctggtatcaa atcgcggggt tgggtcgtct
     8461 ccccagcccc gcacatctca cacgatcggc gctggtgcct gtgcgcaagc ctgcgcggtg
     8521 ctgattaacg ccagtaaaaa cgccttttcg ctctcgttaa ctccctgcaa tccctcggcc
     8581 gctgtcctga tacggtttaa catgctgcta attgcggatc acaacgtcgc ttaacgctac
     8641 ggcgcatttg tccttttcaa tggcgcgagc tgcggcttcc ttaacgttcg gaatccctgt
     8701 agggaacaag accacggcgg cggaatcctc gccggtgaca cgcggcccct tcacgaattg
     8761 atttgagttc aggttatagt ttttcgtgct cgccacggtc agatcggcca gcagcccgcg
     8821 ccggtggcgt agtgggccgc attgtggccg cgcttttcat cgttggcggc ttatcccttt
     8881 gtgtggggat catcaccgga acgtttcact aatcgaaaca atgctataac atacccgacc
     8941 ccgaagagac gcggggaagc agtaagagag acgaaataat gacaatcagc ccaaagacgc
     9001 aagccacgtt agacgaaatg gacgcgacga tcgcccatta ccgccgtaac ccgatgttac
     9061 cgcgtaatgc aggcggcgat cgcctgggag cacgcagagg aggccgcttt agtcgctttc
     9121 ctgaacgcgg aggatgagga tcgggccttt cgtgagcagg tggccgcgaa cgagcaggat
     9181 ttagagcagg agccggagat catcgacgac cacggcgggc taacgttcga tgaatggtta
     9241 gccggtggcc gcagcgccta cgaggcacaa caggccgatg attactcatt ctttcgctaa
     9301 ctgattaccg gcccgcgaga cggcgggcca gaacgacagc cagagacgac gccatgacat
     9361 taaccgccat ttttgcagga gccgccgccg ttatcgggct ggcctttgct taccgcctgt
     9421 atgagacacg caacgacgcc caacaggacg agccaaaagc cccaccagcg cccgcagctg
     9481 ttaaaccggt acaaccacaa cccccgcgcc gcaaaaagcg cctatgggcc gccccccttg
     9541 ccgtattcat tgccgccgag gttgctttac acatgctgat cgctactggc ggttgtgctg
     9601 acggctggca ctccgcgagc attggccgcg ctggcgcttg ttcgtatcac ggcggcgtga
     9661 accattccgg gggctttatc ctcctgatct ccctggccct tgccggttac acgttttacc
     9721 aggtaacgaa agaccgcacg aagaaataac ccaccagccc ggaagagacg ccgggagcga
     9781 caaagagaga cgaaccgatg aaacacgccc ccctgattgg ccgccttttg gcccttgccc
     9841 tcaccatgac cgcaggcagc gcagcagcca ccaccggcga tcggatgttc gaagcccagc
     9901 agcacgggat cgccaacatt tgcgagaaat cagccaaccc ggccgagtgc gccgcagccg
     9961 ttaacgtgct tttggtaggc actgcgaacc agatcaccac ggcgacactt tgcgagctgg
    10021 gcgaaccggc gaacgccgcc gaagcccgga aatgtgaagc cgcgaaacag taccgcgatc
    10081 gactggatgc cgcagggcac caggccgccg ccgagctggg aatgagcagc cactaagccg
    10141 caggaagaga cgagacgatg aaacgaacct taacggccgc agcgctggcg ctggtggcaa
    10201 tgacggcgca cgcccaggaa aacccctttg accagttcga caaagaggcc aagccaaccg
    10261 cagagcagta gaagggccgc gagatggcga tcggcatgtt ggaagcaacc gaaaacttat
    10321 ttaacagcat ttgcagcaac accacagatc caaagggctg tttagccgga ctaacccaga
    10381 ttctggaaga ggcccacaaa gacgggatgt tagttggggt cgtctcagaa aacggaaaat
    10441 aaagcacgct aagcgtgcgt ggaggctggc acccagcggt acagcgtcgg aatggacacg
    10501 ccgaggttct tggccacgtc cttgggcggc accccgctgg ccagcagctt cttggccgac
    10561 tcgatcttgc tgtcggtcat cttcggcttg cggccgcctt tgcggccgag ctgcttggcg
    10621 acttccagcc cggcgcgggt gcgctcgacg gtcagctcgc gctccatttc ggcaaggctc
    10681 gccatgacgt ggaagaagaa ccgcccggat ggtgtgccgg tgtcgatgga gtcggtgagg
    10741 ctcctgaact ggacaccgtg cttgtgcaga tcgccgacca gatcgaccag ttgcttgacc
    10801 gaccggccca gccggtcgag cttccagacg accaaagtat cgccttcgcg cagcatttcg
    10861 agcgtcttgg ccaagccagg ccggtctgcc cgcgtgccac tcaccttgtc ctcgaagacc
    10921 tttttacatc cggccttgct caaggcttcg cgttgcagct ccaggttctg atcctgcgtc
    10981 gagacgcgcg catagccaat caacatggct tgtctcgcgc ccggtcgatg cgttcctgca
    11041 tcgcctgcat cacttcttcg tgggtgtacg atctggcgtt ggcgtcggtg gcttgccgca
    11101 gggcttcctc aacctcgcgc gtcatccgct cgtaatcctc cggccacagc gcttgctcca
    11161 tgcgcagcga cgcctgaccc agcaggtgca gcaggctgaa cagccgcatg tcgttggtgg
    11221 cgacgatgcg ctcccgaatc tgctcctgaa tagcttcgct agcccgatgc gcttgtggtg
    11281 tggcagtccc ctcgtagtca gcggggaatt ccgcttcctc ggcaatcctt gcccaggcgc
    11341 tggccagcgc ctcgatggtt gacgtgctca tttccgccgc tcctgtgctc tttggcgaat
    11401 caaccggcca aggggcctcg acgcgaaaac cagcagcatc acgcctatcg gataccaggt
    11461 cgagaagacc accaaggcat cgaaggctgg ccgtccggtg ttggtaggca gtacggcggt
    11521 cacagccatc aacccgccga ccgtccagat gatgcgccac acgtagggca tcacgcgggg
    11581 cacgtagccg tcatcgaaag cggtctggta gtagcggcgc aggccgcgct cggcaagcgc
    11641 ctggcgctgc cgctccgaca gcgcatccgt ccggccatac cagcgccgga atggtggaca
    11701 gcgcagcagc aaaggggtga agaggatcat caccgccacg atcgcgacac cccacgccat
    11761 gacggcgccg gcatcgggcc gcttggcgtt ctcgatcacg ggcgcgaaga cgcccggagc
    11821 accgatcatc cagaacagcg caatgtgctg atggaaggag agcttcattt gctcatccac
    11881 ttgcgcagca ggcgcttttt cagggaggcg cgttcttgcg ggttgcgtcc cttgtgattg
    11941 gcgatgcgat ccgccgtggc ggcctggcgc ttgacgggcc agtaggagcg gccatccttg
    12001 cccatcgacc agacgctgct ggcctggttt tccagcaggg gcagatgggc gctcagggct
    12061 tcgggcgacg cgctggtcag cgccgtgcgc tcacgggtgc gccagcgctg atgccagagc
    12121 ttcttgtcct cgcgctcgct gccgcaggtc gtgtgcccga cgatgggtgt tttgcggcgg
    12181 ctgcggctca taacgtagtg gtctccaaga acattcagga ctgatcccag gcgtcgatgg
    12241 tcaagacctg atcggcagga caggcggcta cgcggtcggg aactggatgg tgttcagtct
    12301 catgccgacc ccattcgatt gatcgcgtcg cttgcggcac gctgcgacgc aaggaggttt
    12361 gcgacctggt ttagcagccg tgtccgctgc atgtctgtta cctatctccc cgaccgctca
    12421 ttggaccaac tccagagatt gggctctatc gctcagccaa tacgaaaccg gcattggctg
    12481 atgccacaac cgagactaac acaaatggct cggtacctgt atttcgcgcc ccgtgcactt
    12541 ggcccggtct tgccacggct atctcacctt ccctgagggc acgaacaatc ccattgccct
    12601 gaaagtaatc agccattccc gacaaaacag tccacgtgtc ttggccgtga ggatgaatgt
    12661 gagccgcaat ttcctgcccg ggatggacat gccaaaccac gataattgag tctcgggttt
    12721 caagcacaac ggaacgaata ggctcgcctt cggacggctg aacatactcg gctacagaaa
    12781 atattctcga ttcaacagtc atcggagatc cctctttcac agttgtcgtt acggtcttca
    12841 tcgtcggcat cctgacgcac ggcgggcaat tgctggagca acgccggcag ccattcctgt
    12901 accgtctccc acaccacatc gaggttgatg tcgaaatagc cgtgagccat gcgattacgc
    12961 atattgcgca tgctgcgcca cggcacgtcg gcatgcgcct gggtgaactc gacgtagcca
    13021 tccatcacct ttgtggccgc ctcgccgatg acgatcaggc tcatgatgac ggcctgctgg
    13081 gtgcgcttgt cggccaagaa gtcgtccttg gccatccctt ccacgaagct gcgcgcatcg
    13141 gttgcggcct gctgaatgtg gtcgaggtaa tcgggcaggc ggttctcgct catatcggtt
    13201 gcgcctccgc gagcaccttg gcccggaact tcggcggcag gtcgccggga gtcagcagat
    13261 cgacgtcaac gccgagcagc gatttcagtt cttcttccaa atcgcccaag tccaacaacg
    13321 tggcaccggg cagcgcatcg accaacaggt cgaggtcgct gccatcccgg tcggtgccat
    13381 gcagcaccga gccgaagacg cgcgggttcg cggcgcgaaa gcggcctacc gcttcacgca
    13441 ctgcgcttcg cttcatgtca agcacaacag acggtcgcat gcgcatcctt tcttatcgaa
    13501 actcgttgag atgatatgca atcaagaata gaatttcaag aactattttc gagaatcgca
    13561 atgccttgat tcccgtgccg cgccggttgc cttggcgggc ttgtcacaaa cctacgtttt
    13621 caagaagaag gaaaccgcat gccccgccgt tcgatcctct ccgccgccga gcgcgaaagc
    13681 ctgctggcgt tgccggacac caaggatgag ttgatccgtc actacacgtt cagcgaaagc
    13741 gacctctcca tcatccggca gcggcgcggc ccggccaatc ggctgggctt cgcggtgcag
    13801 ctctgctacc tgcgctttcc cggcgtcatc cttggcgctg atgagccacc gttcccgcca
    13861 ttgctgagac tggtcgccaa ccagctcaag gtcggcatcg aaagctggga cgagtacggg
    13921 cagcgtgagc agacccgacg cgagcacctg gtcgagctgc aaacggtgtt cggcttccag
    13981 ccgttcacga ttggccacta ccggcaggct gtccagttgc tgaccgagct ggccatgcaa
    14041 accgacaagg gcatcgtgct ggccagagcc ttgatcgagc acctgcggcg gcagtcggtc
    14101 attgtgcccg ccctcaacgc cgtcgagcgg gcgagcgccg aagcgattac ccgcgccaac
    14161 cggcgtctct acgacgcctt ggctgagccg ctgacggacg tgcatcgccg tcgcctcgac
    14221 gatctgctca agcgccgcga caacggcaag acgacgtggc tggcctggct gcggcaatcc
    14281 ccggtcaaac cgaactcgcg gcacatgctg gaacacatcg aacgcctcaa ggcgtggcag
    14341 gcgctcgacc tgccctccgg catcgagcgg ctggttcacc agaaccggct gctcaagatc
    14401 gcccgcgagg gcggccagat gacgcccgcc gacctggcga agttcgagcc gcagcggcgt
    14461 tacgcgaccc tggtggcgct cgccatcgag ggcatggcca ccgtcaccga cgaaatcatc
    14521 gacctgcatg accgcatcct gggcaagctg ttcaatgccg ccaagaacaa gcatcagcag
    14581 cagttccagg catccggcaa ggcgatcaat gccaaggtgc ggctgttcgg gcgcatcggc
    14641 caggcgctga tcgaggccaa gcaagcgggc cgcgatccgt tcgccgccat cgaggccgtc
    14701 atgtcctggg atgctttcgc cgagagcgtc accgaagcgc agcggctcgc gcaacccgag
    14761 gacttcgatt tcctgcaccg catcggcgag agctacgcca cgctgcgccg ctacgcgccg
    14821 gaatttctcg acgtgctcaa gttgcgggcc gcgcccgccg ccaaggacgt actcgacgcc
    14881 atcgaggtgc tgcgcagcat gaacagcgac aacgcccgca aggtgcccac cgacgcgccg
    14941 accgagttca tcaagccgcg ctggcagaag ctggtgatga ccgacaccgg catcgaccgg
    15001 cgctactacg aactgtgcgc gctgtcggag ctgaagaacg cgctgcgctc cggcgacatc
    15061 tgggtgcaag gctcgcgcca gttcaaggac ttcgaggact acctggtgcc gcccgcgaaa
    15121 ttcgccagcc tcaagcaggc cagcgaattg ccgctggccg tggccaccga ttgcgaccag
    15181 tacctgcatg accggctgac gctgctggaa acgcagctcg ccaccgtcaa ccgcatggcg
    15241 ctggccaacg agctgccgga cgccatcatc acggagtcgg gcctgaagat cacgccgctc
    15301 gatgcggcgg tgcccgatac cgcacaggcc ctgatcgacc agacggcgat gatcctaccg
    15361 cacgtcaaga tcaccgaatt gctgctggag gtagacgaat ggacgggctt cacccggcac
    15421 ttcgcccacc tgaagtcagg cgacctggcc aaggacaaa
//
