LOCUS       NZ_CP046169            19255 bp    DNA     circular CON 20-APR-2024
DEFINITION  Enterococcus faecium strain WGS1811-4-7 plasmid unnamed3, complete
            sequence.
ACCESSION   NZ_CP046169
VERSION     NZ_CP046169.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN12930511
            Assembly: GCF_016864255.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19255)
  AUTHORS   Nygaard,R.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-NOV-2019) Dept. of Microbiology, Haukeland University
            Hospital, Jonas Lies vei, Bergen 5021, Norway
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-FEB-2019
            Assembly Method                   :: UniCycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 119.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016864255.1-RS_2024_04_20
            Annotation Date                   :: 04/20/2024 06:16:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,220
            CDSs (total)                      :: 3,127
            Genes (coding)                    :: 3,012
            CDSs (with protein)               :: 3,012
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 115
            CDSs (without protein)            :: 115
            Pseudo Genes (ambiguous residues) :: 0 of 115
            Pseudo Genes (frameshifted)       :: 44 of 115
            Pseudo Genes (incomplete)         :: 73 of 115
            Pseudo Genes (internal stop)      :: 22 of 115
            Pseudo Genes (multiple problems)  :: 20 of 115
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP046169.1.
            Bacteria and source DNA available from Randi Monsen Nygaard, Dept.
            of Microbiology, Haukeland University Hospital, Bergen, Norway.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="WGS1811-4-7"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="unnamed3"
                     /geo_loc_name="Norway:bergen"
                     /lat_lon="60.23 N 5.19 E"
                     /collection_date="2017-02-03"
                     /collected_by="Haukeland University Hospital"
     gene            complement(join(19235..19255,1..267))
                     /locus_tag="F9Y88_RS15820"
                     /old_locus_tag="F9Y88_15725"
     CDS             complement(join(19235..19255,1..267))
                     /locus_tag="F9Y88_RS15820"
                     /old_locus_tag="F9Y88_15725"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /protein_id="WP_060763464.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPAT
                     RLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIGSVAKF"
                     /name="DUF4158 domain-containing protein"
     gene            392..997
                     /locus_tag="F9Y88_RS15825"
                     /old_locus_tag="F9Y88_15730"
     CDS             392..997
                     /locus_tag="F9Y88_RS15825"
                     /old_locus_tag="F9Y88_15730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002321606.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERPE
                     FQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNEL
                     LDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRL
                     VFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
                     /name="recombinase family protein"
     gene            complement(1042..1695)
                     /locus_tag="F9Y88_RS15830"
                     /old_locus_tag="F9Y88_15735"
     CDS             complement(1042..1695)
                     /locus_tag="F9Y88_RS15830"
                     /old_locus_tag="F9Y88_15735"
                     /inference="COORDINATES: protein motif:HMM:NF012706.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_224813426.1"
                     /translation="MKRTWGKNLTILMLGIIITGCGEKSQETAKETKAYTFAVSTTVQS
                     LDPKLAIDPTSQLVLNNVMEGLYKLNAKGEIVPGGANGLPEISKDGLKYVIRLRKDAMW
                     SNGTPVVADDYVYSWKRTLSNQDSPNIGFFESIKNGKEIISGTMKPDKLGVYAKDKNTL
                     VINLSTPIPYFTSMLINTAFFPQKQEVVEKEGDRYGTNSDSVIYNGPYIGVHGT"
                     /name="ABC transporter substrate-binding protein"
     gene            1984..2376
                     /gene="merR"
                     /locus_tag="F9Y88_RS15835"
                     /old_locus_tag="F9Y88_15740"
     CDS             1984..2376
                     /gene="merR"
                     /locus_tag="F9Y88_RS15835"
                     /old_locus_tag="F9Y88_15740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /GO_function="GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="WP_001863748.1"
                     /translation="MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYDD
                     VKRVGFIKRIQELGFSLSEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKRIE
                     TMLDDLKQRCPDEKQLHSCPIIETLT"
                     /name="merR"
     gene            2405..4300
                     /gene="merA"
                     /locus_tag="F9Y88_RS15840"
                     /old_locus_tag="F9Y88_15745"
     ARG             2406..4297
                     /name="merA"
                     /gene="merA"
                     /gene_name="mercury(II) reductase"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="96.04"
                     /coverage="100.0"
     gene            4460..5782
                     /locus_tag="F9Y88_RS15845"
                     /old_locus_tag="F9Y88_15750"
     CDS             4460..5782
                     /locus_tag="F9Y88_RS15845"
                     /old_locus_tag="F9Y88_15750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="WP_060763465.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKLY
                     KHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKSIQ
                     EQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRPRLV
                     LTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNPILPHAKVV
                     VDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFLLDTWL
                     GNLPALKEAYELKEEFYWIWDTPDPDEGHLRYSQWRHRCMSSNSKDAYKDLVRAVDNWH
                     VEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKRKPRFNSS
                     AFNKAMLYDTFNWYEVNDHDITDNFGVDFSTPIKNLEKGDL"
                     /name="ISL3 family transposase"
     gene            complement(5909..7414)
                     /locus_tag="F9Y88_RS15850"
                     /old_locus_tag="F9Y88_15755"
     CDS             complement(5909..7414)
                     /locus_tag="F9Y88_RS15850"
                     /old_locus_tag="F9Y88_15755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_060763466.1"
                     /translation="MKVSDVISVILKSGIREYKCLNSKIKPIGYKAEGKKGAIFGFRSK
                     KLMTESRGIVLTSQEGLAENEDKFTHWTPNVYSYGAYADEKRIIVKGHNERNLQQINTF
                     VIDFDRLTGEKLDSQMILDAAIDLELMPTLILETPGGFQAYFILENAWYISSKNNYQSI
                     EVAKRVSENLRKAFAEELPSVDLGCNHFGIARIPRTDNIVYYYPALTHDIQQLIQWSMK
                     YEPAKTYKKPLLSLVKNKYKQVNEMWYRQLISNPKIVGAKGIMGRNNVIFTLSLANYAS
                     GVDLEDCLNEMDLFNSSLERPLKDRERVRIVKSAYSGKYRGASKTYVQELVSNWGLESL
                     SEEKMFTQQRNTWYKFKKERHKRKKSHLSEWKEDILAYLETQCYRYRPEVRLKKTDLQA
                     AITFNGQSIPKRSLDRALKELMAEGKLFVQIKAGRNGGLVVATRKALIRTVIQVKQQVK
                     SAYKQGIKTFFKEADMLVRIFREPDKYSQRVDHYKQLNLWNTG"
                     /name="primase C-terminal domain-containing protein"
     gene            8118..9008
                     /gene="prgP"
                     /locus_tag="F9Y88_RS15855"
                     /old_locus_tag="F9Y88_15760"
     CDS             8118..9008
                     /gene="prgP"
                     /locus_tag="F9Y88_RS15855"
                     /old_locus_tag="F9Y88_15760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA superfamily DNA segregation protein PrgP"
                     /protein_id="WP_010714376.1"
                     /translation="MANTIIFGQQKGGVGKTTDTCMITLVAAMLMKKRTILIDIDLQAN
                     ATNFMTKTFGVETVPQTLMSALENGDLRPAIVNLKENLDLIPAGYDMRLYTEFLTENFD
                     NTIDRTFYLKNLIEEIKDDYDYIFIDIPPSTDLKVDNAMVACDYLVVVQETQQFSFEGS
                     QRLIFDYIQTLVDDFGSDVPIQIAGILPALLQQKRPMHQKLVEETIDTFGRDNVFNTII
                     QNHARLEWYPRIGFQFQDYHDKKMIALFADIFCELEERITLYKSNGDIQDYFYTPRYIL
                     DGKLTSLGKEISLNV"
                     /name="prgP"
     gene            9001..9285
                     /locus_tag="F9Y88_RS15860"
                     /old_locus_tag="F9Y88_15765"
     CDS             9001..9285
                     /locus_tag="F9Y88_RS15860"
                     /old_locus_tag="F9Y88_15765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_010714377.1"
                     /translation="MSSLINRKIPQGATANKEADTKRKVTIQKKSSKKILASERKNIKV
                     SPSTFDLIKTISTMKSYKNYEFIDKAVESYIQNNLTEREQRILKNLISK"
                     /name="hypothetical protein"
     gene            complement(9318..9650)
                     /locus_tag="F9Y88_RS15865"
                     /old_locus_tag="F9Y88_15770"
     CDS             complement(9318..9650)
                     /locus_tag="F9Y88_RS15865"
                     /old_locus_tag="F9Y88_15770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6440 family protein"
                     /protein_id="WP_010714745.1"
                     /translation="MPLTLILGGEYIYYDKNLGMMVAGDNSNSELIEQSDNVPLDRHKC
                     KEHVFKDKRFVEKESESLTLLGYKIVVDTVTGVNYLETPKGGITPLLDKNGKICIDKKK
                     SINKKG"
                     /name="DUF6440 family protein"
     gene            complement(9953..10150)
                     /locus_tag="F9Y88_RS15870"
                     /old_locus_tag="F9Y88_15775"
     CDS             complement(9953..10150)
                     /locus_tag="F9Y88_RS15870"
                     /old_locus_tag="F9Y88_15775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_048669782.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCPK
                     CHRRYKQKQGEYVAITIIKE"
                     /name="hypothetical protein"
     gene            complement(10184..10483)
                     /locus_tag="F9Y88_RS15875"
                     /old_locus_tag="F9Y88_15780"
     CDS             complement(10184..10483)
                     /locus_tag="F9Y88_RS15875"
                     /old_locus_tag="F9Y88_15780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="WP_000366408.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFLV
                     CGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
                     /name="BRCT domain-containing protein"
     gene            complement(10524..11141)
                     /locus_tag="F9Y88_RS15880"
                     /old_locus_tag="F9Y88_15785"
     CDS             complement(10524..11141)
                     /locus_tag="F9Y88_RS15880"
                     /old_locus_tag="F9Y88_15785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001224538.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFKR
                     PEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTASY
                     KQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPPEFP
                     AIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
                     /name="recombinase family protein"
     gene            complement(11466..11861)
                     /locus_tag="F9Y88_RS15885"
                     /old_locus_tag="F9Y88_15790"
     CDS             complement(11466..11861)
                     /locus_tag="F9Y88_RS15885"
                     /old_locus_tag="F9Y88_15790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002304891.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIVD
                     YFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKKKE
                     YNYIVKAKVSKRFIFNPKLEIYSVVIE"
                     /name="hypothetical protein"
     gene            complement(11941..14292)
                     /locus_tag="F9Y88_RS15890"
                     /old_locus_tag="F9Y88_15795"
     CDS             complement(11941..14292)
                     /locus_tag="F9Y88_RS15890"
                     /old_locus_tag="F9Y88_15795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="WP_000344083.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQV
                     ELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVYTP
                     YLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLNVNY
                     LEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGNSGNY
                     VRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKGLLSSA
                     GDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTTEELNNI
                     FSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAVDLDMLGE
                     EILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMSTGYSGNLG
                     FPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNYIAKYNQKVI
                     NQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRKIYDEYRNKLT
                     NSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWLGDLMTCWGEVK
                     KLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDSTALSALKTYYCDK
                     GAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFIDKIVNNSLGTDFT
                     YLDFIGDEGKVANGFSEKIIQFQENRSKLN"
                     /name="glycoside hydrolase domain-containing protein"
     gene            14417..15097
                     /locus_tag="F9Y88_RS15895"
                     /old_locus_tag="F9Y88_15800"
     CDS             14417..15097
                     /locus_tag="F9Y88_RS15895"
                     /old_locus_tag="F9Y88_15800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338443.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_010713944.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPD"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(15244..15891)
                     /locus_tag="F9Y88_RS15900"
                     /old_locus_tag="F9Y88_15805"
     CDS             complement(15244..15891)
                     /locus_tag="F9Y88_RS15900"
                     /old_locus_tag="F9Y88_15805"
                     /EC_number="2.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="WP_002403315.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKNK
                     GYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWTES
                     NVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNSRFL
                     LPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
                     /name="type A-8 chloramphenicol O-acetyltransferase"
     gene            complement(16073..17512)
                     /gene="aph(2'')-Ia"
                     /locus_tag="F9Y88_RS15905"
                     /old_locus_tag="F9Y88_15810"
     CDS             complement(16073..17512)
                     /gene="aph(2'')-Ia"
                     /locus_tag="F9Y88_RS15905"
                     /old_locus_tag="F9Y88_15810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="WP_001028144.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
                     /name="aph(2'')-Ia"
     gene            complement(17513..17905)
                     /locus_tag="F9Y88_RS15910"
                     /old_locus_tag="F9Y88_15815"
     CDS             complement(17513..17905)
                     /locus_tag="F9Y88_RS15910"
                     /old_locus_tag="F9Y88_15815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000393259.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYT
                     LLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACH
                     VYEKLGGKNDYKDEIVYVYDYEKGDK"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(18012..>18323)
                     /locus_tag="F9Y88_RS15915"
                     /old_locus_tag="F9Y88_15820"
                     /pseudo=""
     CDS             complement(18012..>18323)
                     /locus_tag="F9Y88_RS15915"
                     /old_locus_tag="F9Y88_15820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            18521..19201
                     /locus_tag="F9Y88_RS15920"
                     /old_locus_tag="F9Y88_15825"
     CDS             18521..19201
                     /locus_tag="F9Y88_RS15920"
                     /old_locus_tag="F9Y88_15825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338443.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_010713944.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPD"
                     /name="IS6-like element IS1216 family transposase"
     ARG             complement(16077..17512)
                     /name="aac(6')-Ie/aph(2'')-Ia"
                     /gene="aac(6')-Ie/aph(2'')-Ia"
                     /gene_name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(15248..15891)
                     /name="catA"
                     /gene="catA"
                     /gene_name="type A-8 chloramphenicol O-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(15245..15891)
                     /name="catA8"
                     /gene="catA8"
                     /gene_name="chloramphenicol acetyltransferase (CAT)"
                     /tool="rgi"
                     /drug_class="phenicol antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(16074..17512)
                     /name="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene_name="aminoglycoside bifunctional resistance protein"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(5917..7414)
                     /name="rep_cluster_180"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="84.687"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          complement(18013..18296)
                     /name="rep_cluster_1118"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="3.17e-147"
ORIGIN
        1 gataatttct ccaggatcaa tatttagttg agttgctaca taactcaata cattttgggg
       61 aatattggta agatctaata taaaagttcc taaaaaacgt agtgagacta actgtagtgc
      121 aaaacctaat ctagtagctg gtcgtcgtat agtctccatc aattctaaat ctttttcatg
      181 caaataaaaa aattggttta attgttctgt actaggttct cctaaataaa tgccaaatgc
      241 ttttttgtta cttttgattt catccattta aaccctccat gaagtaaatt ttaagtctac
      301 ataaaattta tttttaaaaa tgctatgata gcagtaaaac tacaagtaaa ttttacatgt
      361 aaattatatc acttttaaaa aggagttttt tatgggaaaa attggctata ttcgagtatc
      421 ttcacaagat caaaatttgg atcgacaatt ggcaatgatg gaaggactta acattgataa
      481 attattccaa gaaaaagcca gtggtaaaga tactgagcgt cctgagtttc aaaaattact
      541 aaattatatc cgtgaaggtg attgcgtcat cgttacatca ctagatcgtt taggaagaga
      601 ttatgaagat ataaaaaata cagttgcttt tatgaaacag aaaaaagtag cgttaaaaat
      661 attagatgca cagtttttag attttaatac tggaaatgaa ctcctggata ccgctatgtt
      721 cgatatgttt ttatcactgc taagttatat tgcacaaaac gagcgtgaga aaattcgtga
      781 acgtcagcgg caaggagtat tattggctca aaaagccggc cgatataagg gacgaccaat
      841 cgagtattct attaactcaa cagatccgca aaaacgctta gtttttaaaa ccgtggtgga
      901 catgttaaag caaggcattc cagttgcaga gattgcaaaa gaaaacggga tctctcgacc
      961 aactatttat aaaataaaga aagcgaatga tttgtagaaa tatactacat tcattcgctt
     1021 ttctaccgca ctatttcgtt tctatgttcc atgtaccccg atatagggtc cattataaat
     1081 cacactatca gagttcgtac catatctatc tccttctttt tcaacaactt cctgtttttg
     1141 aggaaaaaat gctgtattaa ttagcataga agtgaaatat gggattggcg tactcaaatt
     1201 aataaccaaa gtattcttat ccttagcata aactcccaac ttatctggtt tcatagttcc
     1261 tgagattatt tctttaccat ttttaataga ttcaaaaaaa ccaatatttg gtgaatcttg
     1321 attacttaac gttcttttcc acgaataaac atagtcatct gcaacaacag gcgtaccatt
     1381 actccacatt gcatcctttc tcaatcgaat aacgtactta agtccatcct tagagatttc
     1441 tggaaggcca ttagctcctc caggtacaat ttcaccttta gcattaagtt tatataatcc
     1501 ttccattacg ttatttaaaa caagttggct tgtagggtcg atagctaact tcggatctaa
     1561 gctttgtact gtagtagaaa cagcaaaagt ataagctttg gtttcttttg ctgtttcttg
     1621 agacttttcc ccacaaccag taataattat tcctaacata agaattgtta aattctttcc
     1681 ccaagttctt ttcaaaaaaa cacccctatt caatttctta tctgattgtt ctagcaacac
     1741 ttagcttaat tatactgtaa aaaaaacggg tcttcggaat atatagtgga attactttct
     1801 taatagttta aaaacaactg gtgtttaaat cggattttct ggtgggatgt taggataatc
     1861 aatagtatta tataaaagta tcaatcacat acgagtgata ctttgggaaa aaaataaaat
     1921 agtccaattt acttgaacgt gtactatggt acacggttta taatattcat ggggtgaaat
     1981 aagatgattt atcgcattag tgagtttgca gataaatgtg gagttaataa agaaacgatc
     2041 agatattacg agcgaaaaaa tttattacaa gaacctcacc gaacggaagc tggttatcgg
     2101 atatattcat atgatgacgt taagcgtgtt gggtttatta aacgaataca ggaacttggt
     2161 ttttctttaa gcgagattta taaattactt ggtgttgtag ataaagatga agttcgttgt
     2221 caagatatgt tcgaatttgt ttctaaaaaa caaaaggaag tgcaaaaaca aatagaggat
     2281 ttaaaacgaa ttgaaactat gttagacgac ttaaaacaac gatgtccaga tgaaaagcaa
     2341 ttacattcgt gtccaataat agaaacatta acatgagaga ttaattaacg aaaggagctt
     2401 ttttatgaat aaatttaagg taaacatttc aggaatgact tgtacgggtt gtgaaaaaca
     2461 cgtagaatca gcacttgaaa agatgggtgc taaaaatatt gagtctagtt atcgtcgtgg
     2521 tgaagcagta tttgaactgc ccgatgatat tgaggttgaa agtgcaataa aggcgattgc
     2581 tgacgcaaac tatcacccgg gcgaagcaga agaatttcaa tcggaacaaa agacgaattt
     2641 attgaaaaaa tatcggctaa acgttgaagg aatgacctgc actggttgtg aagaacatat
     2701 tgcggttgct cttgaaaatg caggtgcaaa agggattgaa gtagactttc gtcgcggaga
     2761 agcactgttt gaactaccgt atgatgtaga cattgatatc gcgaaaacag cgattactga
     2821 cgcacaatat caaccgggcg aagcagaaga aatacaagtg caatcggaaa aaaggacaga
     2881 tgtaagttta aatgatgaag gtaactatga ttatgattac atcatcatcg gttctggtgg
     2941 agctgccttt tcatctgcca ttgaagccgt tactttgaac gcaaaagtgg ctatgattga
     3001 gcgtggaacg gtgggtggaa cttgcgttaa tgtcggatgc gttccttcta agaccttatt
     3061 aagagcaggg gaaatcaatc atctagcaaa aaataatcca tttgtgggat tacacacttc
     3121 ggcttcaaat gttgatttag cgccattagt aaaacaaaag aatgatttag taaccgagat
     3181 gcgaaatgaa aaatatgtga atttaattga tgattatggt tttgaattaa taaaaggtga
     3241 agcaaaattc gtaaatgaaa atacagttga agtaaatggc aatcaaatca cagccaaaag
     3301 atttttaata gctacaggtg cttcttcaac tgcacctaat attcccggat tagatgaagt
     3361 agattattta acaagcacta gcttattgga attaaagaag gttccaaatc gtcttaccgt
     3421 aattggttca ggatatatcg gcatggaatt aggacaacta tttcataacc tcgggtcaga
     3481 agtcactttg attcaaagaa gcgagcgtct attaaaagaa tacgatcctg aaatttcaga
     3541 agccattact aaggccttaa cagaacaggg aattaattta gtaacaggtg caacctatga
     3601 acgagttgag caagatggag acattaaaaa agttcatgtt gagataaatg gtaaaaagcg
     3661 aattattgaa gcagaacaat tgctaattgc cactggaaga aaaccaaata cagaatcatt
     3721 aaacttacat gcagcaggcg ttgaagttgg ttcccgtggt gaaattgtca ttgatgatta
     3781 tcttaaaacg accaattccc gaatttattc agctggagat gtcactctcg gtccccaatt
     3841 tgtttatgta gctgcttatg aaggtggact tgctgctcgt aatgcaatcg gaggactaaa
     3901 tcaaaaggtc aatttagaag tggttccagg cgttacgttt acttctccat cgattgcaac
     3961 ggttggttta acggagcaac aggcaaaaga aaaaggatat gaagtgaaaa catcggtatt
     4021 gccgttggat gctgttccaa gagcgctcgt taatcgggaa acaacaggtg ttttcaaatt
     4081 agtggcagac gcgaaaacat tgaaagtgtt aggggcgcat gtagtggcag aaaacgcagg
     4141 agacgtaatt tatgcagcaa cattagctgt gaaattcggt ttaactgttg gagatctgag
     4201 agaaacgatg gctccatatc taacaatggc agaaggattg aagctggctg tcctaacttt
     4261 tgataaagat gtttcgaaat tatcttgctg tgcaggctaa gggaactttt ttacaactcc
     4321 ctattcaagt gaaccagcta atgctttaag ggattttcta agtgcatttg tggtcacaaa
     4381 aataatttaa cactgatgat ttcgacatca aatctataat tgatacctta acaccgcaga
     4441 gtaataaagg atgaataata tgtcagactt attatcccta ccagacatta aaacaataga
     4501 gccgccacaa gaaaatgaaa ccgatatgat gtttaaagtt gaagcagtcg gaccacctga
     4561 acgttgtcct gaatgtggtt ttgacaagtt gtacaaacac agttcaagaa atcaactaat
     4621 tatggatttg cccattcgtt taaagcgagt gggcttacaa ttgaaccgta gacgatacaa
     4681 gtgtcgtgaa tgcggatcta ccttctggga acgcctaata tctgtagatg agaagcgtag
     4741 tatgaccaaa aggcttttaa agtccattca agagcaatcc atgtctaaga cctttgtaga
     4801 agtcgcagaa agcgttggtg ttgacgagaa aaccattagg aacgttttta aggactatgt
     4861 ggcactcaaa gaacgtgaat accagtttga aactcctaag tggcttggga tagacgagat
     4921 acatattatc cgtagacctc ggcttgtatt gactaatatt gaacgcagga ctatttatga
     4981 catcaagcct aaccgtaaca aggaaacagt catccaacgt ctttcagaaa tcagtgacag
     5041 gacttacatt gagtacgtca caatggatat gtggaagccc tacaaagacg cagtgaaccc
     5101 tatccttcca cacgctaaag ttgtcgtaga taagtttcat gtagttagaa tggctaatca
     5161 agccttagat aacgtcagga agtctttgaa agcccatatg agccaaaaag aaagacgtac
     5221 ccttatgcgt gaaaggttta tccttctaaa gcgtaaacac gatttaaatg aacgtgaatc
     5281 attcctctta gatacttggt taggtaatct tcctgcttta aaagaagcct atgaactcaa
     5341 agaagagttt tactggatat gggatactcc tgatccagat gaaggtcatc ttcgttatag
     5401 tcaatggaga caccgttgta tgtccagcaa ctctaaagac gcatataaag acctcgtgag
     5461 agccgtagac aactggcatg tcgaaatatt caactacttt gataaaaggc tcactaatgc
     5521 ttatacggag tcaattaaca gcattattag gcaggtagag cgaatgggta gaggttactc
     5581 gtttgatgcc ttacgagcca aaatcctttt caatgagaag ctccataaaa agcgtaagcc
     5641 acgatttaat tcaagtgctt tcaataaagc tatgttatac gatactttca attggtatga
     5701 agtgaatgat cacgacatta cagacaactt tggtgtcgat ttttccacac ctattaagaa
     5761 tttggagaag ggtgatttat aagccctttt ccaccataaa atccgaatac ccaaaaaaac
     5821 aaaaatatac agaattagga taataactaa caaaaacgaa aacaagtata aaagaaatat
     5881 aatgtatagg cacttgacat gttttatttt atcctgtatt ccacaaattt aattgcttat
     5941 aatgatctac tctttgactg tatttatccg gttctctgaa gattcttact aacatatcgg
     6001 cttctttaaa aaatgtctta atgccctgtt tgtacgcaga ttttacctgt tgcttcactt
     6061 gaatgaccgt acgaattaac gctttacgag tggcaactac tagtccccca ttccgtccag
     6121 cttttatttg tacaaataat ttaccttcgg ccatcaattc ttttaatgca cggtcaagag
     6181 aacgtttagg aattgattgt ccgttgaaag taatcgctgc ttgcaaatct gttttcttca
     6241 gtctgacttc aggtctgtat ctataacatt gggtttcaag gtaagctaaa atatcttctt
     6301 tccattcgga aaggtgagat ttctttcttt tatgacgttc cttcttaaat ttgtaccaag
     6361 tatttctttg ttgtgtaaac attttttcct cagacagcga ttctaagccc caatttgaca
     6421 ctaactcctg tacataagtc ttacttgcac ctctatactt cccagagtaa gcacttttta
     6481 caattcttac tcgttctcta tcttttagag gacgttctaa agaactgtta aaaagatcca
     6541 tctcatttag acagtcttct aagtcaactc ctgatgcata attggccaaa gataaagtga
     6601 aaatcacatt attccggccc ataatccctt tagcgcctac aatttttgga ttactaatta
     6661 attgtcgata ccacatttcg ttcacttgtt tatatttatt tttaacaagt gaaagtagcg
     6721 gttttttata tgttttcgct ggctcatatt tcattgacca ttggattaat tgctgtatat
     6781 catgtgttaa agctggataa taatagacaa tgttgtcagt tctagggata cgtgctatcc
     6841 caaaatgatt gcaacctaaa tcgactgaag gcaattcttc agcaaatgct tttcttaagt
     6901 tctcagatac tcgtttggcc acttcgattg actgataatt atttttggac gaaatatacc
     6961 aggcattttc aagaataaag tatgcttgga agccccctgg tgtttccaaa ataagggttg
     7021 gcattaattc cagatcgatt gctgcatcga gaatcatttg agaatctaat ttttcgcctg
     7081 ttaagcgatc aaaatcgatt acaaaagtat tgatttgttg caagttgcgt tcgttgtgcc
     7141 cttttacaat tattcttttt tcatctgcat atgcaccata gctgtaaacg ttaggtgtcc
     7201 aatgagtaaa tttatcttca ttttcagcta agccttcttg agaagtaaga acgattccac
     7261 gagattccgt cattaacttc ttggatctaa acccaaaaat agcacctttt tttccttcag
     7321 ctttatagcc gattggttta attttgctgt ttaaacactt gtattcacga ataccacttt
     7381 ttaaaataac tgaaatcacg tcagaaactt tcatcttatc accacccatt ctatatttaa
     7441 aaaaaggaga actgcaggca ttctacagct ctcctttaaa ccttatttgc agctaaaata
     7501 tagctcaaaa tcttgatttt taaggtccca aatgatataa ttaaaaagac taagagagct
     7561 gcaactctct gtaatctaaa actataatgg gacgaaagag aatcatgaaa tgctgtgtac
     7621 attttgattc tgtaatttag ttgatcggca aatcaactaa gttaccgtct ctattttttt
     7681 gtctataatt caattagtaa atgtatcttt tttctattca ttcaaattct tctttagaat
     7741 acatgtcact acaacttttg taaagtaaaa attttctctc aaataatcat tcttaattta
     7801 tttttgtatc cttttatctt tgtatccttt tatcttttta tctttttatc tttttatcct
     7861 ttaattttat tgttgtatct ttttatcttt gtatcctttt atctttttat ctttgtatcc
     7921 ttatttagaa gtctatttaa taacttttct tataaaatgc tatctgatta aataagtatg
     7981 ttttaagata attagaaaaa agatacattt atctatttac aattaattct atttgtatta
     8041 ctatttaaat atagaaaaaa gatacaaaga tacatttatc ttttattaca ttttgattac
     8101 aaggaaggag tatattgatg gctaatacaa ttatatttgg acaacaaaag ggcggggtag
     8161 gaaaaacaac tgacacttgc atgataacgt tggtagctgc gatgctaatg aaaaagcgta
     8221 ctattttaat tgatattgat ttgcaagcaa atgcaacaaa ttttatgaca aaaacatttg
     8281 gggtagaaac ggtacctcag actttgatgt ctgctcttga aaatggcgat ctacgtcctg
     8341 ctatcgtaaa ccttaaggaa aacttagatt taattcccgc tggttatgat atgcgtctat
     8401 acactgaatt cttaacagaa aattttgata atacaataga tagaactttt tatcttaaaa
     8461 accttattga agaaattaaa gacgattatg attatatttt tattgacatc ccaccttcaa
     8521 ccgatttaaa ggtagataat gctatggttg catgtgatta cttggttgta gtacaagaaa
     8581 cacaacaatt ttcttttgag ggaagtcaac ggctaatttt tgattatata caaaccttag
     8641 ttgacgattt tggctcagac gttccaattc aaattgcagg cattttacct gcattgttac
     8701 aacaaaaacg cccaatgcac caaaaattag ttgaggaaac aatagacaca tttggaagag
     8761 acaatgtttt taacactatt attcaaaatc atgcacgttt agagtggtat ccacggattg
     8821 gatttcaatt tcaagactat catgataaaa aaatgattgc tctttttgca gatattttct
     8881 gtgaattaga agaacgcatc actctttata aaagtaatgg tgatattcaa gattattttt
     8941 atactccgag atatatatta gacggaaaat taacttccct gggaaaggag attagtctaa
     9001 atgtctagtt tgataaatcg taaaatccca caaggggcaa cagcaaataa agaagcagat
     9061 acaaaacgaa aagttactat tcaaaaaaaa tcgagtaaaa agatattagc ttcagaaaga
     9121 aaaaacatca aagtgtcccc ctctactttt gacttaatta aaaccatatc aacaatgaaa
     9181 agctacaaaa attatgaatt tattgataaa gctgtagaaa gctatataca aaataattta
     9241 acagaacgtg aacaacgtat cctcaaaaat ttaatctcaa aataaataaa aaaggataaa
     9301 aagatacatg tatcttttta tcctttttta tttattgatt tctttttatc aatgcagatt
     9361 ttaccatttt tatcaagtag aggcgtaatt cctcctttag gagtttctaa ataattcaca
     9421 ccagtaacag tatcaactac aattttatag cctaatagag ttaaagattc actttctttt
     9481 tcaacaaaac gtttgtcttt aaatacatgt tccttacatt tatgtctgtc taatggtacg
     9541 ttatctgatt gttctatcaa ctcactattt gaattatccc cggcaaccat catgcctaaa
     9601 tttttatcat aataaatata ttctccacct agtattaagg ttaatggcat aaaaatcttc
     9661 ctttctttaa ttttcttacc gtcctttttc tcttttttta acggctttcg ttacttacct
     9721 ttttgttcat tttctacgca caatcaatcg attaaacaga ttgcctctta ttccaataag
     9781 taaatttcaa gtgcaaatca tcctattttt aaataggatc tgttgtcaac tttttcttaa
     9841 ttctatcaaa aaacggaaga ttttgcttgc aaaccaattc ccttttacta aattaaaata
     9901 ggtttttatt tagtatgaaa cagaaaccaa cattgaagta aatcttattt gtttattctt
     9961 taattattgt aattgctaca tattctcctt gtttctgttt gtatcggcga tggcatttag
    10021 gacagtaaaa gtaatttttt tgataaacac tttttgctaa ttccccacag tcacactcca
    10081 cgtgaaaagc aatatttcga ttaaaactag ttatttcaat gccccaacga tcataagatt
    10141 ttcgcttcat aaaaattttc ctccttgtaa attttactaa cgattataaa taccgttgcc
    10201 attctttcaa ctgttgacta attaacgcat aaaattcgac ttctgataaa atggtaatct
    10261 catgacctaa cgcaatcaag tcccgcgcgg tttgttcctt ttttgtatag agagaatcat
    10321 caaacaacga cttagaatac tgaccacaaa ccaggaaatt tgtttttgaa gtaacacttg
    10381 attgacaatg gccgtttaaa gagtgaacca aaccgatggc ttgggttcgt gtcatttgct
    10441 gcagcgttcc agtaaaaacg accctttgat tcgttaagtc cattttcaaa ctctcccttc
    10501 ccgtctaata gctgttatat ctatcaagaa aagtggtgca aggtatgttc atattctttc
    10561 acccgtcgat aaaaggtatt tcgtttcatg cccaattgat ccatagcata gactgcagtt
    10621 atctttcctg ctttccagtc agaatagatc gcaggaaatt caggaggtaa agcaattttc
    10681 tttctgccga attttacacc cttttgtttc gcagcttcta cgccttctct ttgccggcta
    10741 ttaattcgtt tccgctcgtc ttcggccata tagctgagta attgcagaat taagtcagag
    10801 ataagcgtct ctaacccatc tagttgcttg taactagcag tatctaacag aggcatgtct
    10861 aacacagaaa tatcaatctg cttttcctta gttaattctc gccattcttc taaaatcatt
    10921 tgtttatttc tgcctagtct atctaatgat tgtagataga gtaaatctcc ttttcgaaac
    10981 atccgtttca ttaattgata ttcagggcgt ttaaaatctt tgccgctggc tttttctaca
    11041 aatatatatt cttcagggat tcctaattcc ttcgcggaaa tcagttgtcg ttcgatcgat
    11101 tgatcataac tactgacccg gatataaaaa aattttctca tcgtttttat ctaccctttt
    11161 ttcactaaaa ttgtttcaaa acaatcagat taaatcagaa acgtttcaaa ttgtattatg
    11221 tggttattat gccatacata aacaaagaaa atcaaggcat gtcaaaaagt atactttttg
    11281 aaacagtaag tttacactcc cgcatgatta tatttattcc gctaaaatac ataaaaatgg
    11341 caggccttaa cggtctgcca ttaaataaac tagttatcca gtttttcttt tatgtcttcc
    11401 atggtatatt ttatttttca catcagaatt tgacttcttt aacttttaca atttttttaa
    11461 cactattatt ctattacaac actatatatt tctaatttag ggttaaaaat aaatcttttt
    11521 gatacttttg cctttacaat ataattgtat tctttctttt tttctttgaa gtcgcttgat
    11581 tcaactgtaa cttcaaacca catttcattt ggagactctt ttaatttttt tacttgaaat
    11641 gaattatctc ttggatcata aggtggtact ctttcaaact caggaagttt tctctgtatt
    11701 tgttcttcag gagtattcgc aaagtaatct actatcttga cagttattaa aagtactact
    11761 attcccaaaa ctataacaaa cataaagata attccacatc cagaattatt tttattattt
    11821 tgagtcagat tattccattc tatttcttcc ataatcatca tgtcctttta caattcatat
    11881 acttatttta tcgtatatat ttaaaaagga aaaggacact gtttaaatag taaacgattc
    11941 ttaattaagt ttacttctat tttcttgaaa ttgaataatt ttttcagaaa atccatttgc
    12001 aactttcccc tcatctccaa taaaatcaag ataagtaaaa tctgtcccaa gtgaattatt
    12061 aactatttta tcaatgaaaa atgaaattat ccctacacct aagatatcaa ctgtttcgtc
    12121 attttctaat aaactatttg ttactgaagc gattttatct gaagaaccaa atctgttctt
    12181 aacaaattga ttaaatctat caatagcacc cttatcacaa tagtacgttt ttaaagccga
    12241 taaagctgtt gaatcagaat ttctttttgc taaggtataa acatttaccg cgtcaacatc
    12301 ttggtataaa tcttctagac taaatgttcc acctgcagcc gtacctacta atgcaaatac
    12361 accttgctcc atttgtattc ctaatttctt aacttcaccc cagcaagtca ttaaatctcc
    12421 taaccaacct gcaaagtcag aaacactatc attgattgtg tcggctagaa acatctgtga
    12481 ttgtaacgtc acaattaagt gaggcaaacc tattattgaa ccagtattag gatctataaa
    12541 ataattatac aggccctcgc tattagttaa tttattccta tattcatcat aaatttttct
    12601 atcatgctct gttacaggag aagaaatgat gtcccatgac aaaccagaat aatttacata
    12661 tctataaaat gtcaaatgag ggttccaagg attatcaaga ccagcttgtg atagatattg
    12721 atacgcacgt accatctgat ttataacctt ctgattgtat ttggcaatgt aattatcatt
    12781 attagtatca tttgataact cattaaatcc gctatctcta cccgatgtag cgattaaatc
    12841 gataccaaca gctccgttgc cacttcctat ggtaaattca acaaattgat caaaagacca
    12901 ttgtctaggc ataggaaaac ctaaattccc actataacca gtcgacatat ctgaaacaaa
    12961 tgcaaacgaa gcatacccgt tattgattat ttgagaacaa acatttcttg ttccgtaaac
    13021 acccgtttga tacccgctat atgacattac agcagatacc cccttaaaat attctccagc
    13081 atatgcaaga atttcttccc ctaacatgtc tagatcaaca gcaaaataaa taactgttgt
    13141 taatggtata tttagatttt ttgctgcatc tatagccttc ttaccatctg ataagccacg
    13201 atcataagta aaataagcta atgctgcacc tccatcttga tagataggaa acacagataa
    13261 atttttagaa aaaatattat tcaattcctc tgtagttaga tacttatttc gttcatcttt
    13321 tccaattcca acagtaccag taagatatct accaactatt tttatatcat tatcaaccaa
    13381 tgtttggatt tgagatctag ttaattgcgt agaagtatct gcgccatctg cagatcttct
    13441 aatatctcca gcgctagaca atagtccttt tattacaaca acatctgcta tttcagtata
    13501 ttcaggcaat accataaatt ttcggaatgc cagtacttct aaacccatat atttagtgaa
    13561 aataccatcg aatgtaccgt cttcaaaata accattaaca tataatccat attgaattat
    13621 tcttacatag tttcccgagt taccttcaga cacaggataa gttttactag ttgtcccatt
    13681 accataagac cctgttgctt cactgggaga atatcctagt tcagcttgta atgcaaaaat
    13741 taatgcttga tttgaatttc tttgataaat accatcacaa ggcattattc ccgtgtattc
    13801 taaataattt acatttaacc attgctgcat ttttctaatt ttactatctc cgccgggaac
    13861 aagaacaaaa gcactcatat caaataacgc tttggcccat ttcgcatcca aaactccagt
    13921 tacagcgctt ccattaaacc ctgcatcagt ctgcaactct tttacagcag tatctaaata
    13981 tggagtatat accccatcga agccacctgg attaatcccc ttacaccaaa aggcaccttg
    14041 aataagaaat acaatatttt taggtagatt tttgccccat ttaggagtaa cctgattatc
    14101 gtacattttt tcagtggtag gtccaaaatt agctactaga ttagtaatac caagttctac
    14161 ttgtagtcct tcaataagtc catagattgt aggccaccct gttcgcccat tttctggaac
    14221 cttatcaaac cctgtaacat tactgtattt cttgtttagc catttctgag tacttaaaac
    14281 catctcatcc ataaaaatcc cctgctttct tgccgaacat acgttcgttt atgtgttgat
    14341 taggttctgt tgcaaagttt taaatctact atcaaataag gtagaataat agaaaaagat
    14401 agcaggagga atgacgatga atcattttaa aggaaagcaa tttcagcagg atgtgattat
    14461 tgtagccgtg ggctactatc ttcgttataa ccttagctat cgtgaagttc aagaaatctt
    14521 atatgatcgt ggcattaacg tttctcatac gacgatttat cgttgggtgc aagaatatgg
    14581 caaactactc tatcaaattt ggaaaaagaa aaataaaaaa tccttttatt catggaaaat
    14641 ggatgaaacg tacatcaaaa ttaaaggaaa atggcattat ttgtatcgag ccatcgatgc
    14701 agatggttta accttggata tttggttacg taaaaaacgg gacacacaag cagcctatgc
    14761 ttttcttaag cggttagtga agcagtttga tgaaccgaag gttgtagtca cagataaagc
    14821 cccctctatt acaagtgcct ttaagaaact aaaagaatac ggcttttatc aagggacaga
    14881 acatcgtacc attaaatacc tgaataattt gattgaacaa gaccatcgtc cagtaaagag
    14941 acgcaataaa ttctatcgaa gtttacgcac tgcctcaccc acgattaaag gcatggaagc
    15001 catccgagga ttatataaga aaacccgaaa agaaggcact ctcttcgggt tttcggtctg
    15061 tactgaaatc aaggtattat tgggaatccc agattaaatc atagataccg taagggattt
    15121 tattctttat ttaaaacttt gcaacagaac cttcaaaatc aaaaccacaa gcaaccaaaa
    15181 aatgtggttg ctataaactt ataaatatca taattactta agtttatgaa agttatttta
    15241 gatttaaatc cattcattta cactatcaac tatattttga aattcactca taaataatga
    15301 aacatggtaa ccatcacata ccgcatgatg aacttgcaat gagactggta aatagatctt
    15361 attattctta ctataaaatt tacctattgt aataattggc aataggaatc tactattatt
    15421 accaatattt aaattaaatg aactaaaatc aatccaagga atcatcgaaa taggaactgt
    15481 gttttcaggt attggttttt taggaaacat ttcattttta tctttatatt caagtaagtc
    15541 actcttataa ctattataaa aagaattaaa actaacattt gattctgtcc aaatgttaga
    15601 aaatttttca gtttctttat taaagactgt atataaaggg tttaattttt cccaataacc
    15661 caaatttccc tcactattaa ttcctgttct aaatacttta ttttgattta taatatttac
    15721 aattgtataa atcaaagcag gatacagttc atatccttta ttttttatca tacttttaag
    15781 taaagtgata tcaaattctt tagtaacact gtaagttgtt tgttgattga aataatgatt
    15841 aaaatattct tttctatccc aagtttccaa attaataata ttaaaagtca tatataattt
    15901 tcctcctaaa tttcatctta tctctttgta tttaggagga ataatcctct gattttttca
    15961 tatattgtgt cacctcttaa acgttaatta tactaaagcc tttattattt ttcatttttt
    16021 taaactattt aatactaatg tcttttataa tagcttttca tatattatat aatcaatctt
    16081 tataagtcct tttataaatt tcttttctac cattttcgat aaattcctgt ttaatatttt
    16141 taattccata aacaatagtt tcaataggat aatattcttc aactatatct tgatattctt
    16201 ttgctttctc aatatctata tttccataca ttcttaatat atcttctcca aaatttgttc
    16261 ctatttcttc ttcactatct tcaagtaagt atataaaatc acaatattca tctataattc
    16321 cagaatctcc aaaatcaatt attccagtta atctattatt gccatctaac aatagatgat
    16381 tacaactaaa atcattatgg cataaacact ttttaccctc aaaaactgtt gttgcattta
    16441 gtctttccat aaaactttct atataatctt tttctatatc agttaaatca ttataaatag
    16501 tttcacgcaa caatatatac tcttctaata cattttgttt attatcaata gtacattcac
    16561 taatatctgt ataatctaaa ccgtgcattt gtcttaaaaa actggcaata tctcgtttta
    16621 acaaattttg ttcttcttct gacatagtag aataaatttc tggtgttaaa aaagttcctt
    16681 taatttcttt ataacctagt atagataatt catcactaat atacgaatat tcaatattag
    16741 gaatttttac attagtttct aaatttgtat ttaaaaaatt atatattgct ttttcttttg
    16801 cataaccttt tttcttatta gtactaaatt ttgttttaaa aatgtattca ttattaacta
    16861 aatatgccac actatcataa ccactaccga ttatttcaat actatctact ttgaaattat
    16921 caaagtaatg ctcaattaaa tatttcattg ccttaacatt tgtggcatta tcatcatatc
    16981 tatattccat taaataacaa tcttcttttt tgccctcgtg taattcatgt tctggcaaat
    17041 cttcaataat tctaaaacca gatttttggt atgcccttat tgctcttgga ttatttttat
    17101 gagggtctaa aataactgca ttagcatttc tttctttttt caaaaattca aaaatcaatt
    17161 taatatatct tgtaccaatt cctttactcc aataatttgg ctctcctata aattgatcca
    17221 taccatagac tatctcatca gtttttggat aatgataatc agtatataac tcatcataca
    17281 ttttatatat ttgtccatat ccaataggaa cattgttata ttcaataatt actctaaaaa
    17341 cttcatcttc ccaaggctct gtataatgtt tttttaatga ttctaatgta tattttttat
    17401 ctctaccacc ataaaattct aatactcttt catcagttaa ccattttaac atcaaaggaa
    17461 aatcatcatc tattaaagtt cttatacata tttcattttc aactatattc atttatttat
    17521 cacctttttc ataatcatat acatatacta tttcatcttt ataatcattt ttaccaccta
    17581 atttttcata tacatggcaa gctctaggat tacctttatc agttattaaa aacatttcag
    17641 aacaaccaat ctctttagaa tattccttaa taaaagataa taattttgaa ccataacctt
    17701 tgtcttgata gttaggtaac attcctattg agtgtaaata aaacattgtt tttccatcag
    17761 gtcttaaaag tgtatagcaa tatgcaaatc ctataatttt attattttct ttagctataa
    17821 acccaaatga actggtatca ttaagaaatc cttttaaatt atcaatatca aaaaccatat
    17881 tatcatcaat taaaacttct tccataaact cagtcaagtc cagactcctg tgtaaaacat
    17941 tgtatagtat tttacacagg attatggact tgactatact aaagtaacat tttgtataaa
    18001 acaaagttac tttacttcca aaatctaaat tcacgttgcc aaaaatcaat ctgcttttgc
    18061 aattgttttt cgttcgcttt taaagtcgat ttcattaaat cagttaaatc aattagagat
    18121 atttctttaa ttaatttttt atatttattc ttagtacgtc tttctaattt tccccattct
    18181 tcttcatcat tcaacaacat aaaaaccatt gctctatcag aagtacgttc gatagttttc
    18241 caatctggtt gtaatatatg taaatcatta aaacaatcgt tccaataatc aaccatatct
    18301 ctttttaatt caatttttat ttttattatt tttaatctct ttaaatatct ttacgcacgt
    18361 atatagactt cataatttta aaattatata gacttcacaa cacaatattt cggtacaact
    18421 tccatgtaaa gtataacaca ctagacggtt ctgttgcaaa gttttaaatc tactatcaaa
    18481 taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt ttaaaggaaa
    18541 gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt ataaccttag
    18601 ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc atacgacgat
    18661 ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa agaaaaataa
    18721 aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag gaaaatggca
    18781 ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt tacgtaaaaa
    18841 acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt ttgatgaacc
    18901 gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga aactaaaaga
    18961 atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata atttgattga
    19021 acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac gcactgcctc
    19081 acccacgatt aaaggcatgg aagccatccg aggattatat aagaaaaccc gaaaagaagg
    19141 cactctcttc gggttttcgg tctgtactga aatcaaggta ttattgggaa tcccagatta
    19201 aatcatagat accgtaaggg attttattct ttatttaaaa ctttgcaaca gaacc
//
