LOCUS       NZ_CP045775             8696 bp    DNA     circular CON 31-OCT-2023
DEFINITION  Bacillus paranthracis strain CFSAN068816 plasmid p2CFSAN068816,
            complete sequence.
ACCESSION   NZ_CP045775
VERSION     NZ_CP045775.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN10574728
            Assembly: GCF_009648955.1
KEYWORDS    RefSeq.
SOURCE      Bacillus paranthracis
  ORGANISM  Bacillus paranthracis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 8696)
  AUTHORS   Mafiz,A., Kastanis,G. and Gonzalez Escalona,N.
  TITLE     Closed genomes of twenty-eight foodborne pathogens from the CFSAN
            verification set by a combination of long and short-reads
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8696)
  AUTHORS   Mafiz,A., Kastanis,G. and Gonzalez Escalona,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-NOV-2019) ORS/DM/MMSB, Food and Drug
            Administration-College Park, 5001 Campus Drive, College Park, MD
            20740-3835, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes, CANU v. 3.12.0, 1.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 84, 43, 113, 105, 195, 264x
            Sequencing Technology :: Oxford Nanopore GridION, Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/31/2023 05:35:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,867
            CDSs (total)                      :: 5,715
            Genes (coding)                    :: 5,522
            CDSs (with protein)               :: 5,522
            Genes (RNA)                       :: 152
            rRNAs                             :: 14, 14, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 15 (5S, 16S, 23S)
            tRNAs                             :: 104
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 193
            CDSs (without protein)            :: 193
            Pseudo Genes (ambiguous residues) :: 0 of 193
            Pseudo Genes (frameshifted)       :: 64 of 193
            Pseudo Genes (incomplete)         :: 131 of 193
            Pseudo Genes (internal stop)      :: 39 of 193
            Pseudo Genes (multiple problems)  :: 35 of 193
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045775.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8696
                     /organism="Bacillus paranthracis"
                     /mol_type="genomic DNA"
                     /strain="CFSAN068816"
                     /isolation_source="Mac and Cheese"
                     /db_xref="taxon:2026186"
                     /plasmid="p2CFSAN068816"
                     /geo_loc_name="USA:CT"
                     /collection_date="2009-06-11"
                     /collected_by="FDA"
     gene            complement(join(8624..8696,1..155))
                     /locus_tag="GH772_RS00055"
                     /old_locus_tag="GH772_00055"
     CDS             complement(join(8624..8696,1..155))
                     /locus_tag="GH772_RS00055"
                     /old_locus_tag="GH772_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869766.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000780193.1"
                     /translation="MKLVNNIRMIMAQKNIDNIAELIRITGVSRNSINKLWHNESVSSL
                     RLDTLIAICEKLDVKLSDLIEYIPGDIESK"
                     /name="helix-turn-helix transcriptional regulator"
     gene            344..631
                     /locus_tag="GH772_RS00060"
                     /old_locus_tag="GH772_00060"
     CDS             344..631
                     /locus_tag="GH772_RS00060"
                     /old_locus_tag="GH772_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000323835.1"
                     /translation="MAYLTAKKVKGNIYFYVSQYVGTQPYYSKHYRYINIYSIGNQKIA
                     LERIAMWLLDNNRIPKELIEIGVSINDVKYWYEKVEKTLQNYSLTNHKNT"
                     /name="hypothetical protein"
     gene            645..908
                     /locus_tag="GH772_RS00065"
                     /old_locus_tag="GH772_00065"
     CDS             645..908
                     /locus_tag="GH772_RS00065"
                     /old_locus_tag="GH772_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000874966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000874968.1"
                     /translation="MAFLTNYKANGKRYFYVEKYVGKKPYTCKQSERIYSIGNERITLE
                     RLTLWILDNSFIPSELIKIGISIDDIENWREKVENTIKRYSL"
                     /name="hypothetical protein"
     gene            complement(1611..1817)
                     /locus_tag="GH772_RS00070"
                     /old_locus_tag="GH772_00070"
     CDS             complement(1611..1817)
                     /locus_tag="GH772_RS00070"
                     /old_locus_tag="GH772_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000947848.1"
                     /translation="MLSEQVIYYWNDELQYYYLAEKKNGSYKFVQPLKKLELDDISDPL
                     EREQMKKMLEIKKRMSETKGNWF"
                     /name="hypothetical protein"
     gene            complement(2265..3644)
                     /locus_tag="GH772_RS00075"
                     /old_locus_tag="GH772_00075"
     CDS             complement(2265..3644)
                     /locus_tag="GH772_RS00075"
                     /old_locus_tag="GH772_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000552047.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="WP_001000650.1"
                     /translation="MNDVLKSNLLDITIDKLSIVADFKEGIKKEEFIRMVTSSNMPYSL
                     QANCSKNFGYEEVLKCDSVDCGYIELAGELKKASVDLPKLISHRIRLEIQIEQEKKARE
                     VGESLLSNAEYQGLFESLADVKELIAETDEDGRLTDERKLKRHERQIELTIEKLKGEIV
                     ALKSEIDEQELATGFKSEAMEKIHEEHVQILLNTLENKEKLIEVKRDELLRNAEMFLQL
                     DANGFLPNNGKKKNDRLLKDVRFEFNPKHMAYNRVVDEAIRLVLGLLENVEVTGIHIAC
                     DYPVKIADLKIKDLSSKSECIYLDRDKKIETMYIGKRGSDNHLCIYNKKRENEENETLD
                     QYPDVEHVTRFEARLRKKKAKEWIDSEYNPFDSIIVGDLEKVDNSKIKVNDRIVLEAIM
                     NDYHGRYFGMMDKDQKSNWRKKIKQHVPKLFDVAGDYEKKKVLLTGELAELMKNKPSKQ
                     K"
                     /name="replication initiation factor domain-containing
                     protein"
     gene            complement(3805..4011)
                     /locus_tag="GH772_RS00080"
                     /old_locus_tag="GH772_00080"
     CDS             complement(3805..4011)
                     /locus_tag="GH772_RS00080"
                     /old_locus_tag="GH772_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001029683.1"
                     /translation="MAKANYVTVGRKPKNGKTPKVQEAFRLPKETVDRINELVNSGRFS
                     KKIDVAEKAFEFYFAHLDKEERK"
                     /name="hypothetical protein"
     gene            complement(4147..4497)
                     /locus_tag="GH772_RS00085"
                     /old_locus_tag="GH772_00085"
     CDS             complement(4147..4497)
                     /locus_tag="GH772_RS00085"
                     /old_locus_tag="GH772_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002026683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000562819.1"
                     /translation="MICDNCMNEVEKEFCQTCHYFGYVEVRYKCSNCSYEGKTIENLDD
                     KVNELFKKGRKLIIEMDTDFKPYLEILVKRGITNPKEVGILFGMYLESKKEDHEGYKTI
                     SKSGFEKFLTTI"
                     /name="hypothetical protein"
     gene            complement(4761..4970)
                     /locus_tag="GH772_RS00090"
                     /old_locus_tag="GH772_00090"
     CDS             complement(4761..4970)
                     /locus_tag="GH772_RS00090"
                     /old_locus_tag="GH772_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001174425.1"
                     /translation="MQKVIVVNGYWHNSNGKWKDTTEELNGLLAEGWKVVNIAPMGAYG
                     FGYDAMGNTANSDHGFASIVVIEK"
                     /name="hypothetical protein"
     gene            complement(5235..5516)
                     /locus_tag="GH772_RS00095"
                     /old_locus_tag="GH772_00095"
     CDS             complement(5235..5516)
                     /locus_tag="GH772_RS00095"
                     /old_locus_tag="GH772_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002026684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002026684.1"
                     /translation="MDYFHGYGVKFIGTVKELAKKNNLTIEETCRILELTMKIDDYDRK
                     DEQLAGIGELIKEMNEQIMGLGEGLSAISERLRDMSEGIALISMDDKE"
                     /name="hypothetical protein"
     gene            complement(5548..6753)
                     /gene="mobV"
                     /locus_tag="GH772_RS00100"
                     /old_locus_tag="GH772_00100"
     CDS             complement(5548..6753)
                     /gene="mobV"
                     /locus_tag="GH772_RS00100"
                     /old_locus_tag="GH772_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033080.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_000086031.1"
                     /translation="MSRFMVCHMQKFKMTDVKGLQIHNQREKESRSNPDIIQERTEQNY
                     DLIHGKENVDYKKLIQDRIQDGVVSDRAIRKDAVVCCSFMISASPDYMNSLSQAEQRRF
                     FEESVCFLKARYGEENFVYASVHVDEKTPHMHVGMVPVNEKQKLSAYSFFKNKSELHDL
                     QDKIYEHVKEKGFDIERGVSSDRKHLSTQRFKVVTLQQEIEKLEQEKKEIDSRLHDLKL
                     SLDKAKSVDEIPVKEKGGFIRSKTVEIALEDFESIKVLAKSSETLREENKHLKNEKVKN
                     EYEKDNLYKEQRFLERKVTDLKRENEGLKGENDFLKKTLERVKDLYKEKLPELAGMIGY
                     VKASILDKMNRKFLKRHFIGDDEVSGAQKFLNHKQEHEEQQKRLKQVRRSQQKNRDQGL
                     ER"
                     /name="mobV"
     gene            complement(7383..8051)
                     /locus_tag="GH772_RS00105"
                     /old_locus_tag="GH772_00105"
     CDS             complement(7383..8051)
                     /locus_tag="GH772_RS00105"
                     /old_locus_tag="GH772_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002081870.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="WP_001270695.1"
                     /translation="MRYSDIKVGNIYYADLNPIRKYEFGDNHLSIILSKGKDKRTVTIV
                     SLTSKSSGLGQNKMNLGIVSGLPKRLVEDRSGNPINTYVVLDQVRTVSANRIQYIKDGK
                     KTDGTDNYIECPVDAFSFSKIVCELADLRIADLNDEDAIGEYHKETFFNYCVKKMIDLT
                     YDIIKGRGIVADKKEEVIYFYNNALAMEKGFLIDNYLKPHDIKNKVLEKFNEIVLMSVK
                     "
                     /name="type II toxin-antitoxin system PemK/MazF family
                     toxin"
     Typing          complement(2297..3635)
                     /name="rep_cluster_268"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="85.544"
                     /coverage="97.0"
                     /evalue="0.0"
     Typing          complement(5552..6753)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="89.776"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gctattaaag tatctaatct taaagacgac acactttcat tatgccaaag cttattaata
       61 gaattacgac tcacaccagt tatccttatt aactccgcaa tattatctat atttttttgg
      121 gccataatca tacgaatgtt atttactaac ttcattcctc ttactcctta tattcaacat
      181 acactctatt ttacttataa agataatttt atgcaattta taaataaaaa taaacctttc
      241 gaacgttata tttatttata tgtattgata ttttaacttt ataaggttaa aatataacca
      301 cggacaaaaa caaaagaata acgaacatga aaggaagaac gatttggcat atctaacagc
      361 aaaaaaagta aaaggaaaca tttactttta tgtatctcaa tacgttggaa cacaaccata
      421 ttactcaaaa cactatagat atataaatat ttactcaatc ggcaatcaaa aaatagcttt
      481 agagagaatc gctatgtggt tattagataa caaccgcata ccaaaagaac taatagaaat
      541 cggagtatcc ataaacgatg tgaaatattg gtatgaaaaa gttgaaaaaa cattacagaa
      601 ctactcttta actaaccata aaaataccta aaaggagcat tactatggca tttctaacaa
      661 attacaaagc aaatggaaaa agatactttt atgtagaaaa atatgttggt aaaaaaccat
      721 atacctgcaa acaaagtgaa cgtatttatt cgattggaaa cgaaagaatc acattagaaa
      781 ggctcacttt atggatttta gataacagtt tcattccaag cgaattaata aagatcggaa
      841 tatcaattga cgatatagaa aactggagag aaaaagtaga aaataccata aaaagatact
      901 ctctataact aaaaacaaga aaaaagactg atatttttat cagtcttttt tcctttaact
      961 atttatattt tttcatcaca aaagggttag atattttaat aatatattta tatatttaat
     1021 aaaagttatg cgtgactttt tgtttttttt catttgcgaa caaaaacaaa cagactttaa
     1081 gggtaaaaag gattaaaaat atacagaaat cacgaaataa aaaattcaca aaacaacaaa
     1141 ttcaaacata atctaaacat ctttttttat cacacaactc gattaaaacg gtgcgacttt
     1201 ttaatgatat atatatatct atgaaatgaa aatgcgagca aagttttttc gttttcagtt
     1261 catcatagag atactatata aactccgtaa tttcggaata cggaattaca aagaaaacag
     1321 aaaacaaaaa tttcgaaaat cgaaaaatcg agatttcaaa ttcaacaaaa ttcaaaatca
     1381 aattccacat caaaatctcc cccaaaaaat aaaccttcaa aaaacgtacg gtattttatc
     1441 gttatatata taactaaaaa aattcatgcg cacactttag ttttccatcc tgtacggtag
     1501 taacgggaag tttcaggata taaactatat agcttataaa tttaaaaaag aattcacaaa
     1561 ttcacgaaat taaagtttta aaaaaagaaa gacattttgt ctttcttttt ttaaaaccaa
     1621 ttaccttttg tttctgacat ccgttttttt atctctagca tttttttcat ttgttctctt
     1681 tctaacggat cactaatatc atctaattct aattttttta acggttgtac aaatttatag
     1741 ctgccattct ttttttcagc taaataataa tactgtaatt catcattcca ataatatatg
     1801 acttgttcac tcaacataaa agcccccagt aatcacctta atattagccc attacaccat
     1861 catagcatca ataaagccct aaaattaact caatacaaaa gagacagttc caaaagtaac
     1921 cgtatcaaaa agtagtccca aataactgat aaacgcatca taaagccaaa aacaagtgtc
     1981 tcaaaaagtc cctaaaatca tttgcaaacg ttcataaaaa tatatataat ttatgaacgg
     2041 tagggttata tgttttatat atataaaaaa ccgcaccctt tttgggttat ttttctttga
     2101 tgacaatcaa tataaaagtc attaaaatga ataatatacg gtatacatgc aataatagtc
     2161 gtagttattc tcaaaactaa atttaagttc taaaccataa aaaaatcctt ccaagtgcgc
     2221 caacactcga aaggattgta agtatatctt tttaaattca acttttattt ttgcttacta
     2281 ggtttatttt tcatgagttc tgctaattct ccagttagta gaactttttt cttttcataa
     2341 tccccagcaa catcaaacaa cttaggaaca tgttgtttta ttttctttct ccaattactc
     2401 ttttgatcct tatccatcat cccaaaataa cgaccatgat aatcattcat gatagcctct
     2461 aaaacaatac gatcgttcac cttaatttta ctgttatcta ctttttctaa atctccaaca
     2521 attatcgaat caaacggatt atattccgaa tctatccatt ctttcgcttt cttcttacgc
     2581 aaacgagctt caaaacgtgt tacatgttca acatcaggat actgatctaa agtttcattt
     2641 tcttcattct ctcttttttt attatagata caaagatgat tatccgaacc tcgtttacca
     2701 atgtacatcg tttctatttt tttatctcta tccaaataaa tacattctga tttactagac
     2761 aaatctttta tttttaaatc tgcaatttta actggataat cacaagctat atgtatacct
     2821 gtaacttcaa cattttctaa caatcccaac actaatcgta tcgcctcatc aaccacacga
     2881 ttatatgcca tatgcttagg attaaattca aatctaacat ctttcaacaa acgatcattt
     2941 ttcttttttc cgttattcgg aagaaaacca tttgcatcta actgtaaaaa catttcagca
     3001 tttcttaaca actcatctct tttaacttca atcaatttct ctttattttc caaagtatta
     3061 agtagtatct gaacatgttc ctcatgaatt ttttccatgg cttcactttt aaaaccagtt
     3121 gcaagttctt gctcatctat ttcagatttc aatgcgacta tttcgccttt caacttctca
     3181 atagtcagtt ctatttgtct ctcgtgccgt ttcaatttcc tttcatcagt taaacggcca
     3241 tcttcatcag tttcagctat caattctttc acatcagcta aactttcaaa caaaccttga
     3301 tactcagcat tagaaagtaa cgattctcca acttctcttg ctttcttctc ctgctctatt
     3361 tgaatttcta gtctaatcct atgagagatt aatttaggaa gatcaactga cgcttttttt
     3421 aattctcccg ccaactcaat ataaccacaa tcaacagagt cacactttaa aacttcctca
     3481 taaccgaaat ttttcgaaca gtttgcctgc aatgaatacg gcatatttga acttgtaacc
     3541 attcttataa attcttcttt tttgatacct tctttaaaat ctgcaacaat acttaattta
     3601 tcaatcgtta tatctaacaa attagatttt agtacatcat tcataacaaa atcctaaacc
     3661 cccaaacagt tatatttttg aacccgtcca aagcctagtt ggataataat cgagaaattc
     3721 tcgaacttta cctgcttatt agaataacag gtaacttttt ttcatcggac tatttcttcc
     3781 ccaccaaaaa acactaaaaa caaatcactt tctttcttct ttgtctaaat gagcaaaata
     3841 aaattcaaac gctttttctg caacatctat ctttttagaa aaacgcccac tattcactaa
     3901 ttcattaatt ctatcaaccg tttctttcgg caatctgaaa gcttcttgta cttttggagt
     3961 ttttccgttt ttaggcttcc ttccaacagt cacataattc gccttagcca tcttttcacc
     4021 tcctcgataa aaccaacaat atcatgatat cattttgcat accattttaa caagtttaat
     4081 tttaaaattc atttcaatat aaacttcaaa gtctacaaat catcaaaatt gctcacctac
     4141 taaaactcaa atcgttgtta gaaatttttc aaatccagac ttagaaatag ttttatatcc
     4201 ctcatgatct tcctttttac tttctaaata cataccaaac aaaattccaa cctctttagg
     4261 attcgtgata ccacgtttca ctagaatttc taagtaaggc ttaaaatctg tatccatttc
     4321 aataataagt tttctcccct tcttaaacag ttcatttact ttgtcatcta agttctcaat
     4381 cgttttacct tcataactac aattcgaaca tttatatcga acctcaacat aaccaaaata
     4441 atgacatgtt tgacaaaatt ccttttctac ttcattcatg caattatcac aaatcatttt
     4501 tctcccccta cagaaacata atatctattt tttttaccat ctaccttttg tatattttac
     4561 tgtatttttt gttcattctt ttaaaattcc atttttaaaa gaaaagaaaa cacaccttaa
     4621 agccttaata tccctgtatt ttcaatagaa ttatccccta agtttttgag gtcacacaac
     4681 ccgtattaca tagggggggt tattccttaa tcttactttc aaaataaaaa aagacgtggt
     4741 gaaatcccac gtcttttcta ttacttctca ataacaacta tcgaggcaaa accatgatca
     4801 gaattagccg tattccccat tgcgtcataa ccaaacccat aagcccccat aggtgctata
     4861 ttaacaactt tccatccttc tgctaacaat ccattcaatt cttctgtagt gtccttccat
     4921 ttaccattac tattatgcca ataaccatta actacaatta ccttttgcat atatacctct
     4981 cccttgtttt gattatcaat atataaattt ctatatatca aatacaattt taatatatat
     5041 gtctaaataa atattttaaa aaacaagagc cattcccaag agccttatat aatatcccca
     5101 tatattcaca tcaacaattt gcgaggacat tatgcaaagc tctacaaacc tcgttaaatt
     5161 atgccaaaca agttccgcta acgctacacg tctaaagaaa aaaagagact cacacagagc
     5221 ctcctaacat accattattc tttatcatcc atagatatta acgcaatacc ttcactcata
     5281 tcacgcaatc gttcacttat agcactcaaa ccttcaccaa gccccataat ttgttcattc
     5341 atttccttaa taagttctcc aatacctgct aactgctcat ccttacgatc ataatcatca
     5401 attttcatag tcaattctaa aattctacac gtctcttcaa tcgttaaatt atttttctta
     5461 gccaattcct tcacagtacc tatgaactta actccataac catgaaaata atccattctt
     5521 ggttgctgat taaataatgt ccccacacta tctctccaat ccctggtccc gatttttctg
     5581 ttggcttctt cgcacttgtt ttaatctctt ttgttgttct tcatgctctt gtttgtgatt
     5641 caagaacttt tgagcaccac ttacttcgtc atcgccaata aaatgtcgtt ttaaaaactt
     5701 gcgattcatc ttatccagta tactcgcttt aacataacca atcattcctg caagttcagg
     5761 gagcttctcc ttatacaaat ctttcactcg ctccaacgtt ttcttaagaa aatcattttc
     5821 gccctttaat ccttcattct ctctttttag atcagttact ttcctctcta aaaaacgttg
     5881 ttctttatat aaattatctt tttcatattc attcttaacc ttttcgtttt taaggtgttt
     5941 attttcctct ctaagcgttt cagaagactt agctaatact tttatacttt caaagtcttc
     6001 taatgcaatc tcgaccgttt tagagcgtat aaacccacct ttctctttaa caggaatctc
     6061 atctacactt ttagctttat ctaaagataa tttcaaatca tgaagacgac tatctatctc
     6121 tttcttttcc tgttctaact tctctatttc ttgttgtaaa gtcaccactt taaaccgctg
     6181 cgtcgataaa tgtttcctgt cgctagaaac accacgctct atatcaaatc ccttttcttt
     6241 cacatgctca tagattttat cttgtagatc atgaagctct gatttgtttt taaaaaatga
     6301 atacgctgat agtttttgtt tttcattaac tggaaccatg cccacatgca tatgaggtgt
     6361 cttttcatca acatgtactg aagcatatac aaagttctct tctccatacc ttgcctttaa
     6421 aaaacaaaca gactcttcaa agaatcgtct ctgttccgct tgagataaag aattcatata
     6481 atcaggacta gccgaaatca taaacgaaca acaaacaaca gcatctttcc taatggctct
     6541 atcagataca accccgtctt gaattctatc ttgaattagt tttttataat ccacgttctc
     6601 tttaccatga atcaaatcat aattctgttc cgttcgttct tgaataatat ctggatttga
     6661 acgactttct ttttcacgtt gattatgtat ttgtaatcct ttcacatctg tcatcttgaa
     6721 tttttgcatg tgacaaacca tgaatcttga catgggcttc gctccttttt cggtggtagt
     6781 tccatgtaaa ctgtagcaca ctacagttta ctgcgtaaac acgtgtgccc tacggggcat
     6841 ttcggctacc accgagccat gacaatcatg gcaaaaaacc atgggctttg cccaaaccca
     6901 caagggaaaa acttcccctt gaccccttac aatcgaactc cccaacccct caatccttga
     6961 ggggctccct cgccggtagg catccccaaa cgttcggttt gggaaaacca agagggtttt
     7021 gttgtagtaa agatgtcaac tccttatcct cccttcggtc cggtaccgtt gacatccccc
     7081 acacaaagtt catatctctt taaaagtaat ccccaataaa aaaagccccc tttattttag
     7141 agttaaaacc ctcaaaacaa aggaagccat cattttcata aataacaatc aaaaagacct
     7201 ttctttttac agaaaggtct ctctatggtt gagccatcac agctcgccaa ctattgttcg
     7261 ggtcatcaca accctaaatt ctacggttga gccatcacag ctctttcgca attagtatta
     7321 actaacgcta cttcttctaa ccacactgta tcaaaaataa taataaaaat caacacttat
     7381 aattatttta ctgacattaa aacaatctca ttgaattttt ccaacacctt attttttata
     7441 tcatgtggtt ttaaataatt atcaattaaa aaaccttttt ccatcgctaa cgcattgtta
     7501 taaaagtata ttacttcttc ttttttatcc gcgacgatcc ctcgtccctt aataatatcg
     7561 tatgttaaat caatcatttt ctttacacaa taattaaaaa aagtttcttt atgatattca
     7621 ccaattgcgt cttcgtcatt caaatcagca atccttagat ctgccaattc acatacaatt
     7681 ttagaaaaag aaaacgcatc aactggacat tcaatataat tatcagtacc atcagttttt
     7741 ttgccatctt ttatatattg aatacgatta gcggacactg tacgaacttg atccaaaaca
     7801 acatatgtat tgatcggatt cccacttcga tcttcaacta aacgtttagg caatcccgac
     7861 actataccta aattcatttt attttgtccc aaaccagaac ttttcgaagt aagagaaaca
     7921 atagtcactg tccttttatc tttaccttta cttaaaatta tacttaaatg attatctcca
     7981 aactcatatt tccttattgg atttaaatcc gcataatata tattccccac ttttatatct
     8041 gaatacctca acaatagttc cccctataat taattactta ttcacaagtt tttaccttta
     8101 aaacataaac aattggacta tattcagctt tcaatcctca tcgctacaca cttgtccatt
     8161 acccttgtac aatatagtaa cttctctttt ttttggtaaa tttgatcacc tacaaatagc
     8221 ttttaaccat tttttaaatc tcacatacca agttaaattt agcttaacat aacaataaac
     8281 aattcgcttt tcaaaaaatg ctctatcttg ttcaataaac aaaaaacata aaaaagagcc
     8341 ctgaaaatag gactcttttt aataatcatc attaccacca tttcatttaa cagcactact
     8401 atgattataa atatagttca acaaaatcac gaagtatgcc agtacctctc atcttccaag
     8461 gtgttgacgc acctagcaag tctacaattc catatcccta attcaaaaca tactcatgcg
     8521 ttaacaaaag aagttgaagt gcgccatata gcaccacaaa ataccattag ccaactatac
     8581 ctttagcata caaaaactat ccaagtacat aaaatcccct aaattatttt gactcaatgt
     8641 cacctggaat atattcaatt aagtccgata atttaacatc taacttctca cagatc
//
