LOCUS       NZ_CP045281            29825 bp    DNA     circular CON 23-JUN-2024
DEFINITION  Escherichia coli strain LAU-OXA plasmid pLAU-OXA4, complete
            sequence.
ACCESSION   NZ_CP045281
VERSION     NZ_CP045281.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN13021417
            Assembly: GCF_009363035.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29825)
  AUTHORS   Moussa,J., Panossian,B., Nassour,E., Salloum,T., Abboud,E. and
            Tokajian,S.
  TITLE     Genetic Characterization of an IncFII plasmid carrying blaOXA-48
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 29825)
  AUTHORS   Moussa,J., Panossian,B., Nassour,E., Salloum,T., Abboud,E. and
            Tokajian,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-OCT-2019) Natural Sciences, Lebanese American
            University, Main Street, Byblos 36, Lebanon
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 30.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009363035.1-RS_2024_06_23
            Annotation Date                   :: 06/23/2024 04:00:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,059
            CDSs (total)                      :: 4,935
            Genes (coding)                    :: 4,674
            CDSs (with protein)               :: 4,674
            Genes (RNA)                       :: 124
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 261
            CDSs (without protein)            :: 261
            Pseudo Genes (ambiguous residues) :: 0 of 261
            Pseudo Genes (frameshifted)       :: 79 of 261
            Pseudo Genes (incomplete)         :: 191 of 261
            Pseudo Genes (internal stop)      :: 47 of 261
            Pseudo Genes (multiple problems)  :: 50 of 261
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045281.1.
            Bacteria and source DNA available from Dr. Sima Tokajian.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..29825
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="LAU-OXA"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pLAU-OXA4"
                     /geo_loc_name="Lebanon"
                     /collection_date="2017-12"
     gene            complement(78..404)
                     /locus_tag="GBF15_RS24845"
     CDS             complement(78..404)
                     /locus_tag="GBF15_RS24845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021563028.1"
                     /translation="MQTITTHEQLFVDGKITERTATHIVTGAHGYETLCTSGYNIRYNE
                     KQELVESCEKIAEGELPVTCPTCFAVWQDVHKFTPGDFDTESGKGDFADTNLTEIMIGK
                     MSDT"
                     /name="hypothetical protein"
     gene            631..963
                     /locus_tag="GBF15_RS24850"
     CDS             631..963
                     /locus_tag="GBF15_RS24850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000807830.1"
                     /translation="MAEIKGKITNPALVNAKVFYNRRTKLGIPTEVFLILMFLNVFAVV
                     LCVMYFSTFSVISLILFVLVSVVPMKFVFHGDPDAHKAWIYGYLSPSRLNNTHAVKRRI
                     TFIDAI"
                     /name="hypothetical protein"
     gene            993..1340
                     /locus_tag="GBF15_RS24855"
     CDS             993..1340
                     /locus_tag="GBF15_RS24855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021563027.1"
                     /translation="MLNRISRKISTFQIMFYVALVTGSVTPAMAAGNSTVKLPTPDDSF
                     LQKIVNWMQSILDLVGGAGALFFAFVSGFACIVLWGLAPQQSQAIGKLFRAAVAAIAAF
                     NLAFFIAWLQK"
                     /name="hypothetical protein"
     gene            1352..3952
                     /locus_tag="GBF15_RS24860"
     CDS             1352..3952
                     /locus_tag="GBF15_RS24860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="WP_000531686.1"
                     /translation="MGQSYNEHLNLAGIEQHSGQVYTYTGGAFGAIELTGVDPTGVTPS
                     QGSRISLLLRNIVQLLPLSVTLTQYYIHNDGVKIRLTGRDNQRSQLLSMRRQAYLNKCR
                     NLNASRIIWTLDVHPEENINRLASAEFLKNLFNSMFDDTARRKVRLALSNRESFIIERQ
                     AFEKQCLLLKETLRDLDLRLSFISEDNRILDSEGIWRLQKFLATFNHHWLAPRRKVTVP
                     NDMWDCLALEGDDIEAITWRGVDMLKIQGVRPVYVRLASVLKIGDESVPECAWALTNGR
                     PVLQRGNYVYFMRFTPASAFKKSLMISGKENELVRTQISLSDLMTDSTSKDILDEKLRR
                     NSHLMKMREELENISYSDERLGICQAGIAVFNTDPDKLLETCADINRSVSQTMQVVWET
                     VAQLDAYKVMQPAYSRNTFRALQLNASQMGAASLFFKSHPGIPEWELNGRMEEAFYILE
                     SDDGVPFFFTPKVKEKLLLLGNGATRGGKTFMKNCIASHFIKFGGLYNCLDIDPGSIPM
                     ANFFGDDGAAFTLDSDFQCGFNMFSMAQSKDDRVFLAHLIEQLKAMAAENDSEQDKYLT
                     PDELENITVCASDLLVQKFSPNEGRLSSITLSTLVSKCGQSVKRKLAPFISNGIYGRLF
                     DNKEDAIGVLDKPVAVYNLSGVKDNHNLARLVHREIFFRVVRLFESPEYRTIPKFFEID
                     EAQYTLSVPHAAEFATQKARTWFKHGGGMGFWTQNPEHYSSLDEWTTLRSSASVFIFMP
                     DNEATVKAFHDAYGFDEEEVNIIRSLKVKQQSYIKIPDMQIAKVVNLFVEAEQYAVCTS
                     TSNEAALAAEIWKRESDPDVAVRQIVEGLITKCNKDLIPTPTETEKDKTEGFFL"
                     /name="VirB4 family type IV secretion system protein"
     gene            3949..4770
                     /locus_tag="GBF15_RS24865"
     CDS             3949..4770
                     /locus_tag="GBF15_RS24865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001231279.1"
                     /translation="MRKQLAVVLFSVMTGLITTPAISSGIPVADAAQILGQARAMMQDI
                     KNYKEYMEQTILNNKELLEAYKQYNQMLEDYKQILREAEGLKDKLSSIDYKNFMDEIAL
                     ISNQFDPVYGGGRMVKNTGNAPWDNAYERNLLLNGYGLTNEEYAEMLAAIPYTSDDRER
                     ARQMFEYRQRRVVEGISKDAFVGELQIQLKKQGKTLGELQERRLRLGDNDTTASIQFLA
                     EQNEQLLQQIQSLQLQQAEAMKYSGRLEDHYFNKRAQQEELKARQLQRAWQ"
                     /name="hypothetical protein"
     gene            4767..5234
                     /locus_tag="GBF15_RS24870"
     CDS             4767..5234
                     /locus_tag="GBF15_RS24870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021563025.1"
                     /translation="MKKYLILFFMMFSASAMAKIGYVDEHQKEVDLKIDALISKYEKEC
                     EGKRNSNMCKSQAWDKAHFEYEDEFRGEDKYNHKHYDGLTKDQAVAKLHELIKLHNIVS
                     KDERNPESWPGKLDTLTINGEINYIVRKHWPAWINPCDKICAELLLRQIGK"
                     /name="hypothetical protein"
     gene            5294..6265
                     /locus_tag="GBF15_RS24875"
     CDS             5294..6265
                     /locus_tag="GBF15_RS24875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_225276482.1"
                     /translation="MSLINRLLFVVLFLSVSFYASAETAMRTNFQNGVSEMVNKILNSP
                     DSDLRVWTIAASTFLAAVTAFVYFWRFVENGGALVDLFTLAIMFMLSMSLLASYSMVVD
                     TITGAFYAISNTLQKLALGNIKPSFLQNFVEGVLTKAISAPSVDIFDGMNMVGMALLWE
                     ICSAILSVAIYLADVWIDVGTAIAKITGVMFIPFLVAPATRGIFDGWFKFYIGWGLAAV
                     VLKITSIVVMIMIRASINSAGSFQGAGDVIASDGTVNGVLNITANNISLLRDICAYSVI
                     AAIMVFSCFIFAYMIGSGVGSASQGLNNMAVKLAKKAAKALL"
                     /name="hypothetical protein"
     gene            6275..6994
                     /locus_tag="GBF15_RS24880"
     CDS             6275..6994
                     /locus_tag="GBF15_RS24880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000923649.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB8/TrbF family protein"
                     /protein_id="WP_000923647.1"
                     /translation="MLLEKKEVEKVNRTAFKDRVGELKKDRNLFFWIALLLAGTTIYQS
                     YSVQEAIEKSQNTTEVVWVKLLPDGSHKISQFTPDNEQPIYTPTVNSLLSKYVQKRYGQ
                     LKETIERDYAEAAVFMSPVLTGEFADPKGFNVAQKVVDIQADMAAKRIYIEIKDIDHYD
                     AIEGQFDGDVKPVIRTLVTYQEITRDYQGKEISSVQQMRRLQWTLLQRNELSKQSLDWL
                     NINPLGIQIIDDKSVQQ"
                     /name="VirB8/TrbF family protein"
     gene            7007..7840
                     /locus_tag="GBF15_RS24885"
     CDS             7007..7840
                     /locus_tag="GBF15_RS24885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_001330925.1"
                     /translation="MLAKRTLLFSGVLAVVMTTFSATAQQCRVVNWRPGTIVKVQSALY
                     LGTRIELPEGSMLLTKEPFSSNALWASTGAANQVMIQPTSEEPEGLKTMVTVFMTNGQT
                     LDIEAVRVSQNQNQQCVQIRGAGMRSADRSALNTAYSMGASGADVARLQNEVNTLRSNR
                     ESEVKNAVLEALRRYRYFIYTRYNWTTGKGFSGKNMISDVYDDGRFTYIRIAKPNRGLL
                     AVHADVGGKPAVIPTKYDDAYAIYHMSGIYPKFTLTLDGVKLEVSRADNATDGES"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            7843..9249
                     /locus_tag="GBF15_RS24890"
     CDS             7843..9249
                     /locus_tag="GBF15_RS24890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="WP_021528502.1"
                     /translation="MEERQEKVEEKPATYRKKIQYYAFGTFGVILVILFINMVISIASR
                     NEEEPKENAKQETASTAPNTTEKFNALLKNSGARPSASVNQANTVGNKDSASNGNPNSE
                     TDKKPVHPYSREKEASQERGARASDAGSPDEIRARFKSDEINRALRARSDKTNFDSTKN
                     TVAGSGNAYAPAASFTGNRTNAQRISDINAEQNGLQERIQMMESKVRADEAALPGRLEE
                     ARIRGEQQFAEARQGGAGSNAKSVTKGSTQSVPSGVVGYTASNPYGASVDGMMKLPVGT
                     VLNAITTFTAISDYSGGSMKAMLTHDIYDATHSYILAPKGSEFVIRVVKASQVNEILQS
                     RIGFQVTWLVLPDGNRVDFKTSSSLDRMGTPAVEGDEVDRHLLAQFLGVAAYALVGTKT
                     SYEGSGDSNESFAGNFGEGARTQAGNIAQKYLQVVPTTTLHAGAPIRVFTEDEIYMKPW
                     RNIYETDYTG"
                     /name="TrbI/VirB10 family protein"
     gene            9227..9721
                     /locus_tag="GBF15_RS25625"
     CDS             9227..9721
                     /locus_tag="GBF15_RS25625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001371524.1"
                     /translation="MKRIIRAEILFFAAFFAFSCQAARSPFQVDRMRESAPVQISQQDV
                     HVQGNFQELQPLDRNQKDPRWQYIDPLSVYMRTVWPDNIRTIRAAVNYLLEPTGYRLVT
                     SHPAPREASLLVDKPLPPIARMQRTMPVVDALQLLVGLDNYVVIDRAHRLVSFQKNGGG
                     V"
                     /name="hypothetical protein"
     gene            9733..9942
                     /locus_tag="GBF15_RS24900"
     CDS             9733..9942
                     /locus_tag="GBF15_RS24900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001220097.1"
                     /translation="MRIIFVAFLAIATVILCLFMTGCAQRYESGHDQLFELSERHIIYR
                     DLTVPASMSNLPEKQQISVPGIEP"
                     /name="hypothetical protein"
     gene            9960..10616
                     /locus_tag="GBF15_RS24905"
     CDS             9960..10616
                     /locus_tag="GBF15_RS24905"
                     /EC_number="4.2.2.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371521.1"
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_131199874.1"
                     /translation="MLAFLISGGISASTDEEILLASITAPGVTSFTDESPSSEWITAMQ
                     GRWGSTTDMKDMRSLREIREAVIAEINAVSEPVVEKTGPENKESTTGIKISEKIQSIIN
                     KYAEKYQISETLLKALIKTESGFNPNAVSRKGAKGLMQLMPVHTKRHNADPFDVETNVK
                     IGTGHLSYLLDKYGDLRLALAAYNAGEGTVDKYGGIPPYKETQQYVNKIMAMLGG"
                     /name="lytic transglycosylase domain-containing protein"
     gene            10619..10978
                     /locus_tag="GBF15_RS24910"
     CDS             10619..10978
                     /locus_tag="GBF15_RS24910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_021528504.1"
                     /translation="MTKIKILILAAFVSFGTAHSASAENGSDALSLTGEFLEQPVNSND
                     PCTVFLCMAGMLKGEYSGECSGAKKKFFSIIRRKHGSFHPGRTFNARKTFLGDCPSAPG
                     DIVGKILDKYGKLRW"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            10994..11437
                     /gene="ssb"
                     /locus_tag="GBF15_RS24915"
     CDS             10994..11437
                     /gene="ssb"
                     /locus_tag="GBF15_RS24915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000101377.1"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA];
                     GO:0006281 - DNA repair [Evidence IEA]; GO:0006260 - DNA
                     replication [Evidence IEA]; GO:0006351 - DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_021528505.1"
                     /translation="MARKGVNEVTLVGFVGNAPVISQASSGDKIAVISVATTETWTDRK
                     TGAEKEKTEWHRVVIFGKTAEITEQYVKKGTLLYIRGKLQTRKWLDRDNIERYSTEIIV
                     NPAGGEMQMLGSRQDKVSGGKAGNDIPENGAGSTDKQQSNETD"
                     /name="ssb"
     gene            11665..12651
                     /locus_tag="GBF15_RS24920"
     CDS             11665..12651
                     /locus_tag="GBF15_RS24920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_021528506.1"
                     /translation="MISPAIDYFAANLPYRPYHSNELLYGLRIDKAAKAVLARYIQHNP
                     PHAMYWLVFDVDRPVAAIDWNDLNAPTPNFTVKNPVNGHAHLFYGLKTAVRVAKDGSIK
                     AIEFAAAVERGLRDKLKSDTGYAGLICKNPLHTYWQVVEWRGELYELAELADYVDLYAP
                     TAANDEQVFDIDFSYGLGRNCWLFNLTRIWSYTAIRQGWPDFSQWKEAVIQRVEMYNVQ
                     LSVPLSHKECVCIGSSIAKWTHRRFTEAGFEQYVADTHTSEIQARRGRKNRSEVQAAKG
                     RKGGIAKGNAYGDKREQARVLRVKGLSYQAIADAIQVSRRSVINWCK"
                     /name="replication initiation protein"
     gene            12892..13155
                     /locus_tag="GBF15_RS24925"
     CDS             12892..13155
                     /locus_tag="GBF15_RS24925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilI type IV pilus biogenesis protein"
                     /protein_id="WP_024186966.1"
                     /translation="MMISILVVSNNGQEELIDFNPDHDLAHIIKSYRTPENRMVCIIQD
                     GKRILRWDRSYASRAKNHWRKVDPDSFEILGSVEYLRYVGQG"
                     /name="PilI type IV pilus biogenesis protein"
     gene            13657..14370
                     /locus_tag="GBF15_RS24930"
     CDS             13657..14370
                     /locus_tag="GBF15_RS24930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371526.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA family replication protein"
                     /protein_id="WP_284692925.1"
                     /translation="MAEKNNSLIPRISPSGVAKQSPCYNIVSRKRRRFLNRWIKSLATV
                     AGRVKIKNELCRRIRHNRYWVNEANKFGIEALCELMLAILDDLDLRSWETRHNLETLAE
                     RAGLVTRSDAGRKSISRASRGCDRLVWLNAIITDKAPFNPYDARCACKHIEVTEDFFAI
                     LGIPLKLVYRERARLLKADPNEIIYSGDARLIAIRVQNWTRKAAAGLARMKAKRDAARQ
                     RKKEYYAHPPTPIPL"
                     /name="RepA family replication protein"
     gene            15061..15369
                     /locus_tag="GBF15_RS24940"
     CDS             15061..15369
                     /locus_tag="GBF15_RS24940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcgAII protein"
                     /protein_id="WP_131199878.1"
                     /translation="METFDTDKFRSELDLLSKRIMPGCGLVFELYQRRLSAAIDEFIAR
                     LPKEQHALAFELARQEFDYLSAEEIADEIRRDAEKGYCCHGFDRDCCPLGCGDLDDY"
                     /name="CcgAII protein"
     gene            15435..16085
                     /locus_tag="GBF15_RS24945"
     CDS             15435..16085
                     /locus_tag="GBF15_RS24945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001478769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001330913.1"
                     /translation="MMVNTKKFVMIALSSLLLAGCDSAKDANKSNFEKAINTKLEKECI
                     TISPLGRFDSKPYPVQLSVAQTNRYTSQERADEINTKEFSMFDALVKAGLLTVKDTLVD
                     ETIGFSKTGKKVPGREYALTENGKKYLKSPERPDFCIGHYKVDEIIDFTEPGDAMGMKI
                     TRVNYTFSPTNIAEWAKSDDIQAAFPLLKFNLKEKQKNRLSLVLKNDGWSAER"
                     /name="hypothetical protein"
     gene            16296..16781
                     /locus_tag="GBF15_RS24950"
     CDS             16296..16781
                     /locus_tag="GBF15_RS24950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_131199877.1"
                     /translation="MNNLRDKKSNPVITLIAVVISLFFLPAIAAGLGTMGEIYIDGLRE
                     LPSFGIKAISVAIWILLVAYLMCCFMKAKKDFIRLPAILTFIGTVLLPFVSSFQKMMII
                     SGSDVSTKATFLSKVTEGLGTMKSGFMFIVPALLCAIASIMLAVGMINILRNRYMGR"
                     /name="hypothetical protein"
     gene            17303..17578
                     /locus_tag="GBF15_RS24955"
     CDS             17303..17578
                     /locus_tag="GBF15_RS24955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000085132.1"
                     /translation="MSQYRLTGKSASRSYELLVGWDTPLSRFFLVIEPELDEPVYSNIY
                     EKDPSSLTLEFFQSVLERYGIENVSLLPGHESGLYEKLHDDRRNNN"
                     /name="hypothetical protein"
     gene            17611..17961
                     /locus_tag="GBF15_RS24960"
     CDS             17611..17961
                     /locus_tag="GBF15_RS24960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000694584.1"
                     /translation="MKIKLGSGSVSVNGVVYEGKGKVISILNNEVIIDGVVHGKAVALP
                     EITVIVNGHVDSLHTELGNIIINGNAGMVKTASGDVSCENVSGNVESMSGNVNCKNVYG
                     GVKTLSGNIYKE"
                     /name="hypothetical protein"
     gene            18281..18904
                     /locus_tag="GBF15_RS24965"
     CDS             18281..18904
                     /locus_tag="GBF15_RS24965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330914.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_001127156.1"
                     /translation="MPKVIAFLNGKGGVSKTTSAVNIATALARKGYKVVVVDTDPQGSV
                     SNWYDDSKCVFDVAEATTEKEIYRLRKALPLHDFIIIDGAAAISAISAAAVMVSDLVII
                     PVTPSPLDFAACGAILAVIEARQDLRPVIARFLITKKVQQTHMLSLLKESIAETSIPAL
                     KTGTSYRQSYIKSMLDGGTIFDTKDSAAKGEISVITEEILGLLK"
                     /name="AAA family ATPase"
     gene            18901..19110
                     /locus_tag="GBF15_RS24970"
     CDS             18901..19110
                     /locus_tag="GBF15_RS24970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partition protein ParG"
                     /protein_id="WP_000041404.1"
                     /translation="MSKMKLGNHKATNTALDALKKPAGATRKLQMNIPEELHLAFKLAC
                     VEDGVDMTQVNIELIQNWLKSRNL"
                     /name="plasmid partition protein ParG"
     gene            19138..19629
                     /gene="yjeJ"
                     /locus_tag="GBF15_RS24975"
     CDS             19138..19629
                     /gene="yjeJ"
                     /locus_tag="GBF15_RS24975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="WP_000456858.1"
                     /translation="MEYTPIALSPGAMLHKGKFIGYVMKIRFSECSGDHLFYLRYDMVV
                     ELARALARKTHQMYLKGTFSTDESSQATLEMEKDYKQHDIYLTSDEISSPSVNNFVALL
                     DYNVRDASLLLSLIKNDNSKIDISIPEAAVEIFTGYMMNTVIKAGGEALSEKLISDIGV
                     "
                     /name="yjeJ"
     gene            complement(19687..19986)
                     /locus_tag="GBF15_RS24980"
     CDS             complement(19687..19986)
                     /locus_tag="GBF15_RS24980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001259442.1"
                     /translation="MRTLEEVIAAQSPESQAIIKAMADEMILETGLQMMREELQLSQKQ
                     VADAMGISQPAVTQLEQRGNDLKLATLKRYVEAMGGKLSLDVELPTGKRIAFNI"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(19983..20333)
                     /locus_tag="GBF15_RS24985"
     CDS             complement(19983..20333)
                     /locus_tag="GBF15_RS24985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000269927.1"
                     /translation="MWTVYFGRLFDEWFEEQELALKRKVLAELRHLEEFGPSLSRPHAD
                     TVKGSRHKNMKELRIQYEGHPIRAFFAFDPIRQAIILCAGDKSNDKKFYDRMIRIADEE
                     FSTHLAELEGKK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            20691..21194
                     /locus_tag="GBF15_RS24995"
     CDS             20691..21194
                     /locus_tag="GBF15_RS24995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021526598.1"
                     /translation="MHQEQDIADALHESLAYFNRYCRYSLKRLAADYQEEIDNYQDDVW
                     EAPQRAARLSAAVKNYKTSRMIEFIFYMAIKLNLDLTPLVVKRLCSCLFQRTGSQELIV
                     EIFGKKQRVNRSADNTMERINDVTERYRKSATRHWRKTLSDIEKVKKGYQKEIRARRKK
                     KSGK"
                     /name="hypothetical protein"
     gene            21381..21731
                     /locus_tag="GBF15_RS25000"
     CDS             21381..21731
                     /locus_tag="GBF15_RS25000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021528495.1"
                     /translation="MKDNQNQSLQVGDATIRIGDIFHTHWGYEQTNIEFYQVVSLHGKK
                     TVGLREIAREVVKHTSWCSAEIRPVPDKFIDEAIHKRRVIAKWGSVLVRFSDVTNAWRT
                     SPEALHHCSWGY"
                     /name="hypothetical protein"
     gene            complement(22299..22895)
                     /locus_tag="GBF15_RS25010"
     CDS             complement(22299..22895)
                     /locus_tag="GBF15_RS25010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021528497.1"
                     /translation="MMERKQLNLRINDQFLIGEIDNKLHSEKLIHKHHVTDAINTIKYL
                     EILFTSSNLKRYKNKEHYIKHIVAKSLLPKAEEIIRIQKDEFSSHYEHLKKTVSEIPNY
                     KDIYNHINNENKKIKIPVLISPVVMMMISLITLTDNIIKQQRILYLCGEISKKDFYSNR
                     RVVLKKFSNVRLKLHHNRKEYSEKLSTLIEKKGMQ"
                     /name="hypothetical protein"
     gene            complement(22892..23350)
                     /locus_tag="GBF15_RS25015"
     CDS             complement(22892..23350)
                     /locus_tag="GBF15_RS25015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021526602.1"
                     /translation="MFRLAKPEDYEFIPDINLWELSFDKRPVRGVRCEDPVLGAQQYND
                     TQQSILLNRQRQKLRKQNFFSLENISWDGVFDWCLSKGTQEECYLIVKLYYAKNKDEHY
                     STLSKLKKHEGFYHESDLYLWVSMFFMSGNKIASTDKLTLVEEKGGYI"
                     /name="hypothetical protein"
     gene            23431..23646
                     /locus_tag="GBF15_RS25020"
     CDS             23431..23646
                     /locus_tag="GBF15_RS25020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001280801.1"
                     /translation="MSDKIQEITQKIEKLQIKLSKIEEEKNKIQSKLVKLEEEKKSIQR
                     KLILQEKREELEMLLDKESFDILFNK"
                     /name="hypothetical protein"
     gene            24967..25659
                     /locus_tag="GBF15_RS25025"
     CDS             24967..25659
                     /locus_tag="GBF15_RS25025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021563020.1"
                     /translation="MIYRFKTDFMRQIAMLFSLGYTRWFGGEIPLNPHYKFVSLKARFD
                     ELYAINATAQQRFRRREKGVANCKFLVWFDEKNATLLWVLLATEGDVYNEEKFYDGMNK
                     KTRISVSGYELKTVPHRGRKPSVSWAMKKETYEKWHADIKKSIRTRNDENIEKLWYSLR
                     RVAGFSELRRQVFKLQRYAMTEWKRSRRGEYPYEKIFVGWLGRFKQSETITDEELLLIS
                     KSKKADIF"
                     /name="hypothetical protein"
     gene            25686..27551
                     /locus_tag="GBF15_RS25030"
     CDS             25686..27551
                     /locus_tag="GBF15_RS25030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001148707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_131199875.1"
                     /translation="MQANDEFLRLVFENIWPWWTYAWVLVFSLLCVFTFSGHAEKSGDK
                     STLRFIIEAARKKLLVAWILCTLLFFLFVYIIAWKHFGEDSHKASLYMELLYERIGDKS
                     FSFGDYCGIAFVLLFPYACQIINRRLIRPKLSSWLRRFRVSQTSDTMSDIRVEKGKYSP
                     KNFNPLDYYKDGHFFLGLDENDKAIYVTDDYLSKVNIKILGATQTGKGVIQGVIADQAI
                     LKNWGLWFWDQKPDKFIYSIMKQRCESEGREIYEVDLNGEGIGDYAPFKNGTKREILDR
                     FFNAFSLETGGTDADYYKNNAQEVMYYIYTFWDRSLNDLQKLLSGSDDRIPEEKQEWIA
                     KNGANIRTQLNKWLELPCLSPVDGQGLNVTELVKSGAVIYVKGSTKDKVVRAVLKSMLR
                     EWSAAVIREQPKNHVLGIIDEARFVISSEVADSLATILSSNASLSIAYQERDDLLNIPD
                     EKPQIAQSIKKGTETNTNLTLVYRCNDETAEWVAKNSGTTAKSLTKLEEVETDGYGAET
                     WKGRRMIGQEEDYYIPVNTVLAVEERVGIMQTMFELSRVLFTCWVPVQRFYTLPARPQT
                     EQDNVQDCIKNDGSISPSDEDYFNPDMISDEELAMINKTVSSDSK"
                     /name="hypothetical protein"
     gene            27608..28672
                     /locus_tag="GBF15_RS25035"
     CDS             27608..28672
                     /locus_tag="GBF15_RS25035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="WP_021563019.1"
                     /translation="MDKTTKTYPFGEIEFFDQLEEHAWDQIHDGMLPIMDLYLDPTVTD
                     IFINRYDNIYTSVNGKYVKTDSSFSSERALKAWIDQIATVLRQPFSTSGNYKYGDVIEP
                     VLDARFPDGSRLMCTDPVISPQGSTVSLRKVPKQILEEKDFINSGMLTRDILDYLISVI
                     QKRKNFIVAGNTGSGKTSLLRLLARYIDTMERVITAEDTQELHIHRYFPLGIALEAAHR
                     KDVNADLPSLVHLTMRGNPDRVWVGEVRTAEAIAAYYMVLASGTIGNATTLHSVTPMGA
                     IRKMTWLMSSYLSIDFQIAQDLIMSEVDVIIQCRRTSKHGRRITDIVEIREGKIVPIFK
                     FDEEQEVHVRFDKK"
                     /name="ATPase, T2SS/T4P/T4SS family"
     gene            29037..29282
                     /locus_tag="GBF15_RS25045"
     CDS             29037..29282
                     /locus_tag="GBF15_RS25045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001623606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system CcdA family
                     antitoxin"
                     /protein_id="WP_001260053.1"
                     /translation="MRTNVAVKKRSINVYLNAGLLEEAKDLDLNVSAISNKALEKAVRE
                     RKRERWIEENRAGIEALNRFVEDTGIFSDDENFGVI"
                     /name="type II toxin-antitoxin system CcdA family
                     antitoxin"
     gene            29282..29599
                     /locus_tag="GBF15_RS25050"
     CDS             29282..29599
                     /locus_tag="GBF15_RS25050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001623607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdB family protein"
                     /protein_id="WP_000808866.1"
                     /translation="MKQFSVYKNKSRNKQAYPYFIDIQAEMLAHLNTRLVMPLTPKDNS
                     NSQVKTLTPVININQVDYVVLTTMITTTDAKNLNSDNVVMDASYLRDQLVSAIDMMILG
                     I"
                     /name="CcdB family protein"
ORIGIN
        1 aactttggag cagttctgca atgttgtttg aattgtttcg tagtcgtatc attatttttt
       61 atgtgatgat tgttttttta tgtgtctgac atttttccaa tcatgatttc tgtgagattt
      121 gtatcagcaa aatctccttt ccccgattca gtgtcaaagt cgcctggcgt gaacttatgt
      181 acgtcttgcc agactgcgaa gcaggtaggg catgttacag gtagttcgcc ctcagctatc
      241 ttttcacaac tttctaccag ttcttgtttc tcgttgtacc tgatgttata gccgcttgtg
      301 caaagcgttt catacccgtg agcgcccgtc actatatgtg tggcggttct ttctgtgatt
      361 tttccatcaa cgaataactg ttcatgcgtt gtgatcgttt gcatgtctgt ctctcataat
      421 tgttggttta tgtgattgtt ggggcgaccg taaaaatata cgccagatga cgggagagca
      481 tcttatttcg tattgctcaa aaaaatatat gacaaatatc acaaaaatga aatacaggta
      541 ttgacatcgg gggggggggg taacgtaaag attataaata taaattttac aaaacgtaaa
      601 aatatactac gtcattcggt aagaaatcaa atggctgaaa taaaaggaaa aataaccaat
      661 cccgcactgg ttaatgcaaa agttttttac aacagacgaa caaagctggg gatacctaca
      721 gaggtctttt tgatcctgat gttcctgaat gtttttgctg ttgtgctgtg tgttatgtat
      781 ttcagcacat tttccgttat ttcgctgatt ttatttgttc tggtatcggt tgttcctatg
      841 aagttcgttt ttcatggcga tcccgatgct cataaagcct ggatttatgg ttatttgtca
      901 ccttccaggc tgaacaatac ccacgcagtg aagcgtcgta tcacatttat agacgctatt
      961 tagggattta accagtaaaa gaggtgtata caatgctcaa tcgcatttcc agaaagatat
     1021 caacattcca gataatgttt tacgtagcat tagtgacagg aagtgtcaca ccggctatgg
     1081 ctgctggtaa tagtacagtt aaacttccta cgccggatga tagtttttta cagaaaatcg
     1141 ttaactggat gcaaagtatt ctggatctgg ttggtggggc tggagctttg ttctttgcgt
     1201 ttgtcagtgg gtttgcttgt attgtgttgt ggggacttgc accgcaacag agccaggcta
     1261 tcgggaaact gtttcgtgct gctgttgcag caattgcagc gtttaacctg gcgttcttta
     1321 ttgcctggct gcaaaaatga ggtgatccac gatggggcag agctataacg aacatctgaa
     1381 tctggcaggc atcgaacaac attccgggca ggtgtatacc tatactggag gtgcttttgg
     1441 tgctattgaa ctgacaggtg ttgatccaac gggtgttacc ccttctcagg gtagccgtat
     1501 ttctttatta cttcgtaata tcgttcagtt actgcccctt tctgtcacac tgactcagta
     1561 ttatatccat aatgacggcg ttaagatccg gctgacaggg cgtgataatc aacgcagtca
     1621 gttactttct atgcgtcgcc aggcatatct taataaatgt cgtaatttaa atgcctcaag
     1681 aattatatgg acgctggatg ttcacccgga agagaatatt aatcgcctgg catctgccga
     1741 gtttttaaag aatcttttta acagcatgtt tgatgacaca gccagacgta aagtcaggct
     1801 ggcactgtca aatcgcgaat cgtttatcat tgagcgtcag gcatttgaaa aacagtgcct
     1861 gttgctgaaa gaaacattac gcgatctgga cttacgcctt tcttttattt cagaagataa
     1921 caggattctt gattcagaag ggatctggcg attacagaag ttccttgcaa catttaatca
     1981 ccattggctg gctccacgcc gtaaggtcac tgtacccaat gatatgtggg attgtctggc
     2041 gcttgaaggt gacgatatcg aggccattac ctggcgtggc gttgatatgt tgaagatcca
     2101 gggggtacgg cctgtttatg ttcgcctggc cagtgtgttg aaaattggcg atgaatctgt
     2161 acctgaatgt gcctgggcgc tgacaaatgg cagaccagtt ttacagcggg gtaactacgt
     2221 ttacttcatg cggttcactc ccgccagtgc ctttaagaag tcactgatga tcagcgggaa
     2281 agaaaacgaa cttgtcagga ctcaaatcag tttgagcgat ttaatgactg acagtacgag
     2341 caaagatatt ctcgatgaaa aattgcgcag aaattcacat ctgatgaaga tgcgcgaaga
     2401 actggagaat atttcatatt cagatgagcg cctggggatc tgccaggccg ggattgctgt
     2461 atttaataca gatcccgata aattacttga gacttgtgcg gatattaacc gtagtgtctc
     2521 tcagaccatg caagttgtat gggagacggt agcacaactg gatgcttaca aggttatgca
     2581 accagcctac tcacgcaata catttcgtgc attacagctt aacgcatctc agatgggggc
     2641 tgcatccttg ttctttaaat cccatccagg tattcctgag tgggagctaa atggacgcat
     2701 ggaggaagcc ttctatattc ttgaatcaga tgatggcgtg ccgtttttct ttacgccaaa
     2761 agttaaagaa aagctactgc ttcttggtaa tggggcgacc cgtggcggca agacttttat
     2821 gaaaaactgt attgccagcc attttattaa attcggtggt ctgtataact gtctggatat
     2881 cgatcctggc tcaatcccaa tggctaattt ctttggggat gatggggctg catttaccct
     2941 tgatagcgat tttcagtgtg gttttaacat gttcagtatg gcgcaaagca aggatgacag
     3001 ggtatttctt gcgcatctta tagagcagtt aaaagcaatg gcagcagaaa atgacagtga
     3061 gcaggataaa tatttaacgc ctgatgaact tgaaaatata acagtgtgtg cgagtgatct
     3121 tcttgtacaa aaattttcgc cgaatgaggg gcgtttaagc tcaatcacgt tgtcaacgct
     3181 ggtttctaag tgtggtcaga gcgttaaacg caagttagcg ccatttatta gtaatggtat
     3241 ttatggacgt ttatttgata acaaagagga cgcgattggt gttcttgata agccggtagc
     3301 tgtttacaac ctttcaggtg tgaaagataa ccataatctt gcgcggcttg tgcaccgtga
     3361 aatcttcttt cgtgtcgttc gtttgtttga atcaccggaa tatcgcacga taccaaagtt
     3421 ttttgaaata gatgaggcac agtacaccct gtctgtacca catgccgcag agttcgctac
     3481 acagaaagcc cgaacctggt ttaagcatgg tgggggtatg ggattctgga ctcagaaccc
     3541 tgagcactat tcatcactgg atgagtggac tacgttacgt tcctcggcgt cggtgtttat
     3601 ctttatgccg gataatgagg caacagttaa agcattccat gatgcttatg gcttcgatga
     3661 agaagaagtg aatattattc gcagccttaa ggtaaaacag cagtcgtata taaagatccc
     3721 ggacatgcag attgcaaaag tggtgaatct gtttgttgag gctgaacagt atgctgtttg
     3781 tacatcaacg tctaatgaag cagccctggc agcggaaata tggaaacgtg aatcagatcc
     3841 cgatgttgca gtgcgacaga ttgtagaagg gctgataacg aagtgtaata aggacttgat
     3901 cccaacgcct acagagactg aaaaggataa aacggagggg tttttcttat gagaaaacaa
     3961 cttgcagtag tcttgttttc tgtaatgaca ggattgatta caacacctgc tatttcttct
     4021 ggcattcctg ttgctgatgc tgctcagatt cttggtcagg ccagggctat gatgcaggat
     4081 atcaaaaact ataaagaata tatggaacag acaattctca ataataaaga attgctggaa
     4141 gcatataagc aatacaacca gatgcttgag gattataagc aaattttacg tgaggccgaa
     4201 gggctgaaag ataaactttc atcgattgac tataagaatt ttatggatga aatagccctt
     4261 atctctaacc agttcgatcc cgtttatggt ggggggcgta tggttaaaaa tacgggtaat
     4321 gcgccgtggg ataatgccta tgagcgtaat ttgttgctta atggctatgg gcttacaaac
     4381 gaagaatatg ccgaaatgct ggcagcgata ccatatacga gtgatgaccg cgaacgtgcc
     4441 cggcagatgt ttgaatatag gcagcgcagg gttgttgaag ggatttcaaa agatgccttt
     4501 gttggtgaat tgcaaataca attaaaaaag caaggaaaaa ctctagggga attacaggaa
     4561 agacgtttaa ggttaggtga taacgatacg acagcctcta tccagttttt agctgaacaa
     4621 aatgaacaac tgttacaaca aattcagagt ttacagttac agcaagcaga ggcgatgaaa
     4681 tatagtggtc gtcttgagga tcactatttt aacaagcgag cgcaacagga agaattaaag
     4741 gcacgtcagt tacagagggc atggcaatga aaaaatatct gattcttttc ttcatgatgt
     4801 tttcagcctc ggcaatggct aagattggct atgttgatga gcatcaaaag gaagttgacc
     4861 taaaaattga cgctctgatt tctaaatatg aaaaagaatg tgaaggtaaa cgcaatagta
     4921 atatgtgtaa atcccaggca tgggataagg cccattttga atatgaagat gaatttagag
     4981 gcgaagataa atataatcat aagcattatg atggcctgac aaaagatcag gcagtcgcga
     5041 agttacatga acttattaaa ttgcataata ttgtttctaa agatgaacgt aatcctgaaa
     5101 gttggcctgg aaaattagac acactaacta ttaatggtga gattaactat atagttagaa
     5161 aacactggcc agcatggatt aatccatgtg ataagatttg tgcggaactg ttacttagac
     5221 aaataggtaa atgatgtagc atttaacaag ctatatcttt aatttggggg ctattatgct
     5281 tcgaggattc tttttgtctt taattaacag actcttattt gtagtcctgt ttttatctgt
     5341 ctcattttat gccagtgcag aaacagctat gcgcacaaac tttcagaatg gcgtaagtga
     5401 gatggttaat aaaatactaa atagcccgga tagtgattta cgtgtctgga ctattgccgc
     5461 atcaactttc ttggctgcgg taacggcatt cgtctatttc tggcggttcg tggaaaatgg
     5521 tggggcgtta gttgatttat tcacgcttgc aatcatgttt atgttatcaa tgtcattgct
     5581 tgcttcttac tcaatggttg ttgatactat cacaggcgct ttttatgcga tatcaaatac
     5641 actacagaaa ctggcgttag gtaatattaa gccgagtttt ctgcaaaatt ttgtagaggg
     5701 cgtgttaaca aaggctattt cagcaccatc ggttgatatt tttgatggca tgaatatggt
     5761 tggcatggcg ctcttgtggg aaatatgttc tgctattttg tctgttgcta tatatcttgc
     5821 tgatgtttgg attgatgttg ggacagcaat agcaaaaatt acaggtgtta tgtttattcc
     5881 ttttttggtt gcgccagcaa caagaggaat ttttgatgga tggtttaaat tctatattgg
     5941 atgggggctt gcagcggttg tacttaaaat aacatctatt gtggtaatga taatgatcag
     6001 ggcatcaatt aactctgcgg gtagtttcca gggcgctggc gatgttatcg cgtcagatgg
     6061 tactgttaat ggcgttctta atataacagc taataatatc agcttgttac gtgatatttg
     6121 tgcatattct gtaatcgctg caattatggt gttcagttgt tttatatttg cgtacatgat
     6181 tggttctggt gtcggctctg caagtcaggg gttgaataat atggcagtaa aactagccaa
     6241 gaaagcggct aaagcattat tgtaaggtga acgtatgctg cttgaaaaaa aagaagtcga
     6301 aaaagtaaat cgcacagcct ttaaggatcg tgttggtgaa ctaaaaaaag acagaaattt
     6361 gtttttctgg attgccttgc ttcttgccgg gacgacgata tatcagtcat attctgttca
     6421 ggaggcaata gagaaaagcc agaatactac agaagtagta tgggtgaaat tattgcctga
     6481 tggttcacat aaaatatcac aatttacgcc agacaatgag cagcctatat atacaccaac
     6541 agtgaactca ttgctgtcaa agtatgtgca gaagcgctat ggacagttaa aagagactat
     6601 agaacgggat tatgcagaag cggcggtatt tatgtctcct gttcttacag gggagtttgc
     6661 tgatcccaaa gggtttaatg tcgctcagaa agttgtggat attcaggccg atatggcagc
     6721 aaaaaggatt tatatagaaa taaaagatat tgaccattat gacgcgatag aaggtcagtt
     6781 tgatggtgat gttaaacctg taattcgaac gcttgttact tatcaggaga tcacaaggga
     6841 ttatcagggt aaagaaattt catcggttca acaaatgagg cgtcttcaat ggacgttgtt
     6901 acaacgtaac gaacttagta aacaatcgct ggactggctt aacatcaatc cgctgggaat
     6961 ccagattatt gatgataaat ccgtacaaca gtaaaggaac ttaatcatgt tagcgaaaag
     7021 aactctctta ttttctggag tcctggctgt tgtcatgact acgttcagtg caacagcaca
     7081 gcaatgtagg gtggttaact ggcggcctgg aacaatagtt aaagtgcagt ctgctttata
     7141 tctgggaact cgtatagaac tgccggaagg ctcaatgtta ttaacgaaag aacccttttc
     7201 ttctaatgcg ctatgggcca gcacgggagc cgcaaatcag gtcatgattc agcctaccag
     7261 tgaagagccg gaagggctga aaacgatggt aacagtattt atgactaacg ggcagacgct
     7321 ggatattgag gccgttcggg tatctcagaa ccagaatcaa cagtgtgttc agatccgtgg
     7381 tgcaggtatg cgttccgcag acagaagtgc attaaacacg gcttacagta tgggggcatc
     7441 cggggctgat gtagctcgtt tacagaatga agtgaataca ttgcggagta acagagaaag
     7501 cgaagtcaaa aacgcagttc ttgaagctct tcgtcgatat cgatatttca tttatacccg
     7561 ttataactgg acgacaggta aaggttttag cggaaagaat atgatctctg atgtttatga
     7621 tgacgggcgt tttacttata tccgtatcgc aaaaccgaat cgtggattac ttgcggtaca
     7681 tgcagatgtc ggaggaaaac cagcggttat tcctaccaag tacgacgatg catatgccat
     7741 ttatcatatg tcagggatat atcccaaatt tacccttacc ctggatggcg taaagctgga
     7801 agtcagccgt gcggataatg cgactgatgg ggagagttaa ttatggaaga acgtcaggag
     7861 aaagtagaag aaaaaccagc tacttaccgt aaaaaaatac agtattacgc ttttggtact
     7921 tttggtgtga tcctggtaat tcttttcatc aatatggtga taagtattgc ctcaaggaac
     7981 gaggaagaac caaaggagaa tgcgaaacag gaaactgcca gcactgcgcc aaatacaacg
     8041 gaaaagttta atgcgctact gaaaaacagt ggtgcacgtc cttctgcctc cgttaatcag
     8101 gctaatacgg ttggaaataa ggatagtgcc agtaatggaa atccgaatag tgaaacagat
     8161 aaaaaacctg ttcaccctta cagccgggaa aaagaggcgt ctcaggagag gggggcgaga
     8221 gcaagtgatg cggggtcacc tgatgaaatc agggcacgct ttaagtctga tgagattaac
     8281 cgagcactgc gtgccaggtc agataaaaca aattttgata gcactaaaaa tactgttgcg
     8341 ggtagtggta atgcatatgc cccggcagca tcgtttaccg gaaaccggac taatgcgcag
     8401 cgtatcagcg atataaacgc agagcagaat ggattgcagg aacgtatcca aatgatggaa
     8461 tcaaaagttc gtgctgatga agctgcttta ccaggacgac tggaagaagc ccggatacgt
     8521 ggggaacagc aatttgcaga agcccgacag ggtggagcag gaagtaacgc gaaatcggta
     8581 actaagggga gtacccagag cgtaccgtcc ggtgttgtgg gatatacagc cagtaatcct
     8641 tatggggcaa gtgttgatgg aatgatgaag ttgccagtag gtacggtcct gaatgccatt
     8701 accacattta cggctatttc tgattattcc ggcggctcaa tgaaggccat gcttacgcat
     8761 gatatctatg atgcgacgca tagctacatt cttgcgccta aaggaagtga gttcgttatc
     8821 agggtcgtta aagcctccca ggtaaacgaa atccttcaaa gccgtattgg attccaggtt
     8881 acatggcttg tattgcctga tggtaacagg gtcgatttta aaacctcgtc gtctcttgac
     8941 cgaatgggga ctccggcggt tgaaggcgat gaggtggaca ggcatttgct cgctcagttt
     9001 cttggcgtag cggcctatgc ccttgtgggg acgaaaacca gctacgaagg ttcaggtgat
     9061 agtaacgaga gttttgccgg gaattttggc gaaggcgctc gtactcaggc aggaaatatc
     9121 gctcaaaaat acctccaggt tgtgccaaca acaacgttac atgcgggagc accgatcagg
     9181 gtctttaccg aagatgagat atacatgaag ccgtggagaa atatttatga aacggattat
     9241 acgggctgaa atattgtttt ttgctgcatt ctttgcattt tcctgtcagg cagcaagaag
     9301 tcctttccag gtagacagga tgcgagaaag tgcgcctgtt cagatatcac agcaggatgt
     9361 gcatgtgcag ggaaactttc aggagttaca accactggac aggaaccaga aagatcctcg
     9421 ctggcagtat atcgatccgt tgagtgttta catgcgtaca gtttggcccg ataacatcag
     9481 gactatcaga gcagcggtga actatctcct ggaaccaaca ggatatcgcc tggtaacgag
     9541 tcatccggca ccgcgtgagg cttcccttct tgttgataag ccattaccgc caattgccag
     9601 aatgcaacgc acaatgcccg tagttgatgc tcttcagttg ctggttgggc ttgataatta
     9661 tgttgttatt gatcgtgccc acaggctggt ttcatttcag aaaaatgggg gcggtgtatg
     9721 aaggaatggt gtatgcggat tatttttgtg gctttcctgg ctattgcaac ggtgattctt
     9781 tgcttattta tgacggggtg tgcacaacgt tatgagagtg gtcatgatca gcttttcgaa
     9841 ctgtcagaac gccatatcat ttaccgggat ctgactgttc cggcatcgat gagcaatttg
     9901 ccggagaagc agcagataag cgtaccgggg attgagccgt gaacgtccgg ttaattttca
     9961 tgctggcgtt tctgatctct ggcggtatca gcgcatcaac ggatgaagaa attctactgg
    10021 cgtcgataac cgcgccagga gttaccagct ttaccgatga atcaccatct tcggaatgga
    10081 ttacagcgat gcagggacgt tggggtagta caactgatat gaaggatatg cgtagtttgc
    10141 gcgagataag agaagcggtg attgctgaaa ttaatgccgt gtcagagccg gtggtggaga
    10201 aaacagggcc agaaaacaaa gaatcgacca caggaataaa aatatctgaa aaaatacagt
    10261 cgataatcaa taaatacgca gaaaaatatc aaattagtga aactttgttg aaagcgttaa
    10321 ttaaaacgga gtctggattt aatccaaacg ctgtcagcag aaaaggtgca aagggactga
    10381 tgcagttaat gcctgtacat accaaaaggc ataatgctga tccatttgat gttgaaacca
    10441 atgtgaaaat tggtacaggg catctttcat atcttctcga taaatacggg gatttacggc
    10501 ttgctctggc tgcatataac gctggggaag gtaccgttga taaatatggc ggtatccccc
    10561 cttataagga aacacaacag tatgtaaata agatcatggc aatgttagga ggttaaatat
    10621 gacaaaaata aagatactga tacttgcagc ttttgtctca tttggaaccg cgcatagcgc
    10681 cagcgcggaa aatggaagtg atgctctgtc actgacagga gaatttcttg agcaacctgt
    10741 taacagcaat gatccatgta ctgttttcct ctgtatggca ggaatgctta aaggtgaata
    10801 ttctggtgaa tgcagtgggg caaagaaaaa atttttcagc attatcagaa ggaagcatgg
    10861 cagttttcat cccggaagaa catttaatgc acgtaaaacg tttcttggtg attgcccgtc
    10921 agcacctgga gatattgtag gcaagatact tgataaatac ggaaaattac gctggtaaca
    10981 gaaggagtaa acagtggcaa gaaaaggtgt aaatgaagtc accctggttg gttttgtcgg
    11041 taatgctccg gtgatatctc aggccagtag cggggataag atcgcggtta tttccgttgc
    11101 aacaactgaa acatggacgg acagaaagac aggtgctgaa aaagagaaaa ccgagtggca
    11161 tcgagttgtt atttttggaa aaacagccga gataacggaa caatatgtaa aaaaaggcac
    11221 gttgctgtac attcgcggga aactgcaaac ccgtaagtgg ctggaccgag acaatataga
    11281 gcgttacagc acggaaatta ttgttaatcc ggcaggggga gaaatgcaga tgctggggag
    11341 tcgccaagat aaagtaagcg gaggaaaagc cggaaacgac attcctgaaa atggcgctgg
    11401 cagtacggac aagcagcaaa gcaatgaaac cgactaacgc gccttcggct tgttcaaccc
    11461 cggagtcact cagaagcaag ttccgagtga ccccggcgtt tttggttttt actacgggga
    11521 tgataatacc catgaggttg atacttggca gagtcagctt gtgggcatta tcaggggact
    11581 ataaaagccc atttaaattg tatttaaatc atccggtaac ggcaagaaaa ataatgtgtc
    11641 attcaggcat aagtgcaggg ccatatgatt agtccggcaa ttgattattt tgcggcaaac
    11701 ttgccatacc gaccttatca ctcgaatgaa ttgctctatg ggcttcgtat cgataaggca
    11761 gctaaagcag tgctggcgcg ttatatacag cataatccac ctcatgcaat gtactggctt
    11821 gtttttgacg ttgacaggcc agttgcggcg attgactgga atgatcttaa tgcgcccaca
    11881 cctaatttta cggtcaaaaa tccggttaat ggtcatgcac acctgtttta tgggttaaaa
    11941 acggcggttc gtgttgccaa agacggtagc attaaggcga tcgagtttgc tgctgcggta
    12001 gagcgaggat tacgtgacaa acttaaatca gataccggct atgcagggct gatttgtaaa
    12061 aatcctctcc atacatactg gcaggttgtt gaatggcgtg gagaacttta tgagttagct
    12121 gaactggctg attatgttga tttgtacgca ccaacagcgg ctaacgatga acaggtattt
    12181 gatatcgact ttagttatgg gcttgggcgc aattgttggc tcttcaatct gacccgtatc
    12241 tggtcatata cagcaatccg gcagggctgg cctgatttct cgcaatggaa agaagcggtg
    12301 attcagcgtg tcgaaatgta taacgtgcag ttaagcgtgc ctttgtctca caaagaatgt
    12361 gtatgcattg gctccagcat cgccaaatgg acgcatagac gcttcactga agctggattt
    12421 gagcaatatg tagctgatac ccatacatca gaaattcagg ctcgtagagg gcgtaagaat
    12481 cgctcagaag tgcaggctgc taaggggcgt aaaggtggca ttgcgaaggg taatgcctat
    12541 ggtgataaac gcgaacaagc aagagtatta cgggtaaaag gattgagtta tcaggcaatc
    12601 gctgacgcaa ttcaagtatc tcgacgctcg gttattaatt ggtgcaaata gcaacctata
    12661 tcagataaca gcaccggatc ttgatccttg cagacagatc ctttgccttt agtgatcttc
    12721 cgattttcag gtattgagtc ttttattaga gagatgatag cgcctgccgc agccccagcg
    12781 accgaaccgc caggtgagcg agtgggcgag gaggcgcaag ggagtcagag gttgatgttt
    12841 tgcacttacg ctcgatgttt gagaactgca agaagacaaa tggagattga gatgatgatc
    12901 agtatacttg ttgtgtcaaa taacggtcag gaagagttga ttgattttaa tcccgaccat
    12961 gatttagcgc acattatcaa atcataccgg acaccagaaa acaggatggt atgtattatc
    13021 caggatggta agcgcattct tcgttgggat cgcagttatg cttcccgtgc aaaaaatcac
    13081 tggcgtaagg tagatccaga cagttttgag attttagggt ctgttgaata tctccgctat
    13141 gttggtcagg gttagttggg gcgttgaaaa cggaaaataa cccacgctaa gactgttttt
    13201 taaccaggct atgataatgc tatctttgac ggatgatggt cattgctctt tgttaatgct
    13261 aacggacgcg tacattagca ttaacttttg tgttatgttg cacgtgaatt tttgagtttt
    13321 aatatttata taatgttatg aatattaaag ataaatgatg aacatgcttt gtgatggctt
    13381 ttggcgcata gattgatctt aacatctgcg catgttattt ttatgcggtt ttgacgaatt
    13441 tataagggtg ggacgttccc gtaacagcgt ccaggggagg gggatagcga atttatagcc
    13501 cccggaatgc aacaaccccc tgatatctct cttagagctt ttgccgggcc aaagaagata
    13561 atcagggggt ccaaagcagg ctgggtgcct gtaagggatt atagcaaatg catttctcaa
    13621 tacaagacct ctgtccggca ataagtgcgg gcggtggtgg ctgaaaaaaa caactcctta
    13681 atcccccgca tatcgccgtc aggggtggca aaacaaagtc catgctataa cattgtgtcg
    13741 cgtaagcgac gccgtttcct caatcgctgg attaaatcac tggcgacggt cgcagggcgt
    13801 gtcaaaatca aaaatgaact ctgccgccgt atccggcata accgatattg ggttaatgag
    13861 gctaacaagt ttggcataga ggcactttgc gaactgatgt tagctatcct ggatgatctc
    13921 gatttacgct cctgggaaac caggcataac ctcgaaacac tggcagaacg tgccggactg
    13981 gtgacacgca gtgacgcggg gcgtaaatct atttcccgtg ccagtagggg atgtgatcgc
    14041 ctggtctggt tgaatgcgat cattacagat aaagcgccgt ttaaccccta tgatgcacgg
    14101 tgtgcctgta aacacattga agtaaccgaa gacttctttg ccatactcgg cattccgtta
    14161 aaactggttt atcgggaacg tgccaggctg ttaaaggcag atcctaatga aattatttac
    14221 tccggtgatg ccagactgat agctatcaga gtccagaact ggacacggaa agcggcagcc
    14281 ggattagccc ggatgaaagc gaaacgcgac gcagctcgac aacgcaaaaa agaatattac
    14341 gctcacccac ctacccctat tccgctctga tacaggctaa cttaccgcct tatggggcgg
    14401 tgtatcggca cgtccataat aaaaaactgt acaaaaaata gtcttagcgt gggttatttt
    14461 ccgttttcca tgtacagaaa agagcaggta taagctgtat cattgggtaa actatgcaca
    14521 ggttgtggat aatcatactt aaagtgcaaa cgatatgccg caattactct tttgcttctc
    14581 ttttagttac ttacgtacta aaagagaagc aaaaaagaaa aacattactg ttatcccctt
    14641 taacaagtga ataacctaaa aacatcggcg caagcgcctc gaaagtagca cccctcgcaa
    14701 gctcggggca ttagaaacaa cagtatccca tcatcacaat cgaactatta ttcacctatc
    14761 tttgctgtaa catcgacggt ctacgaccac ctaccacctg aatagctgta agttccgtgc
    14821 ggtcaggctt agcagggggc tgacgcggtt cctggcgaca tgaaactccc tggttagggg
    14881 tatcggcgcg acctggcatc tgtgactcta tgaaaccatt tttcgcgcct tccatgccgc
    14941 taaagcggca tattccataa gaatttacat gcgcgtatac tttataatca gtatcaacga
    15001 aagttgcttg cccaaatcag aggcaacaat cgcatcaaat aacttgcgca ggtgataatt
    15061 atggagactt tcgatactga taaatttcgc tcagaactgg atcttttatc aaaaaggatc
    15121 atgcctggtt gtggtcttgt ttttgagcta tatcaacgtc gtttgagcgc tgcgattgat
    15181 gaatttatcg ccagattgcc gaaagaacaa catgctctgg cgtttgaact ggctcgccag
    15241 gagtttgatt atctttctgc agaagagatt gcagatgaaa tacgccgaga cgcagaaaaa
    15301 ggctattgtt gccacggctt tgatcgcgat tgctgccctc ttggttgcgg tgatttagat
    15361 gattattaat ttaaagggat aaatatattt acatactgaa aatataggct gattttttct
    15421 gataaagagg aaaaatgatg gttaatacaa aaaaatttgt gatgattgcg ttaagttcat
    15481 tattgttggc agggtgtgac tcagcgaagg atgccaataa atcaaacttt gaaaaagcga
    15541 ttaatacgaa acttgagaag gaatgcatta caatcagtcc tcttgggagg tttgatagta
    15601 agccttatcc agttcaatta tctgtcgccc aaactaatcg atatacatct caggaacggg
    15661 cagacgaaat aaataccaaa gagttttcca tgtttgatgc actggttaaa gctggtttat
    15721 tgacagtaaa agataccctg gttgatgaaa ctattggatt ttctaaaaca ggtaaaaaag
    15781 tgcctgggcg tgaatatgct ctgacagaga atggaaaaaa atatctgaaa tctccagagc
    15841 gccctgattt ctgtattggt cattataagg ttgatgagat cattgatttt actgaacctg
    15901 gtgatgctat gggaatgaaa ataacaaggg tcaattacac attcagtcct acgaatattg
    15961 ctgaatgggc aaagagcgat gatattcagg cagcatttcc acttcttaag tttaatttga
    16021 aagagaaaca gaaaaaccgt ctatctctgg ttttgaaaaa tgatggatgg tccgctgaac
    16081 gataggtaga taaatgacgt tgctacgtgg tctccctctt ttgctgattt cacgtagcac
    16141 tctcactctg ccgctacttc tcgttatgct gaacagatga ttgaaaaata aggagaatta
    16201 aataatctct tgattttata atcctatgat tataagatta ttgtgtgtga gtgtttggat
    16261 agagaattat tgtaatcaag tgggagatat tatttatgaa taatttacgt gataaaaaat
    16321 caaatcctgt tattacatta attgctgtcg tgatttcttt attcttcctt cctgcaatcg
    16381 ccgcaggact ggggactatg ggagaaattt acattgatgg tctgcgtgaa ttaccgtctt
    16441 ttggtataaa ggcgataagt gttgcaatct ggatactttt agttgcatat ctgatgtgtt
    16501 gcttcatgaa agctaagaaa gattttattc gcttacctgc tatactgacg tttattggga
    16561 cggttctcct gccttttgta agtagttttc aaaagatgat gattatatcc ggttcagatg
    16621 tttccaccaa agcgaccttt ttgagcaagg ttacagaagg tctgggaaca atgaaaagtg
    16681 gatttatgtt tatagtacct gctttattat gtgcaatagc ttccattatg ctggctgttg
    16741 gaatgataaa tattttacgt aatcgttata tggggcgcta atctgatgtg cggtgattgt
    16801 gaggttgatt tgattataga agggagttaa tgtggaactg ataacagata atttttatga
    16861 gtgggtggtg gtgtctctcg ctattttgaa ttttatcgtt atattgaaat ataacgataa
    16921 aataactttg ttgttaacga cgatgattag cctacttctt gcttcaatta tatttgccag
    16981 ataaacgact taatagctac aggggggggg caagccggaa acctggattt ttccgcgatc
    17041 agtaaggggt cggttaggga aacgtacaat attgtacgtt tccctaacgc agccctacag
    17101 gaactggcac ggctgaaaat ctgaccgcct ggcctgcata ccgcaatcat ttgcgttatc
    17161 cagacgtatc tccgcttagc gggtgttatc gcagaaattc ccacggaacc cctataagaa
    17221 taacaaaagg atataatccc ttgattttgt aatcatatga ttatatgatt gtttttgagc
    17281 gtgaattatt caggagggag ttatgagcca gtatcgttta acaggaaaat cagcatcgcg
    17341 tagttatgaa cttctggttg gctgggatac cccgctttcc aggttttttc ttgttattga
    17401 gccagaactt gacgagccgg tatattcgaa tatttatgag aaagatccat catctttgac
    17461 gcttgagttt tttcagtcag ttcttgaacg ttacgggata gagaatgtat ctctgctgcc
    17521 tggtcatgag tcaggtttgt atgagaaatt gcatgatgat agaagaaata ataactagcg
    17581 gtttttaatg gaatatgcag gaatattgcg atgaaaataa aactagggtc aggttcggta
    17641 tctgtaaatg gtgttgtgta tgaaggaaag gggaaagtta tttccatatt aaataatgaa
    17701 gtcattattg atggtgtcgt tcatgggaaa gccgtagctc ttcctgaaat tactgttatt
    17761 gttaatggtc atgttgattc attacatacc gagttgggaa atataatcat taatggtaat
    17821 gctggtatgg ttaaaactgc atcgggggat gtttcttgtg aaaatgtttc aggaaatgtt
    17881 gagtctatga gtggtaatgt taattgtaaa aatgtttatg gtggagttaa aacattatct
    17941 gggaacatat ataaagaatg agttcattaa aaccccgtac aatatattgt acgggggtag
    18001 tacagaagag gtattgggtt gctacatttc caggttatat gcagaaacca ttttcatttt
    18061 atcaggtatt tattttttct taatgagata gttcacaaaa tcatcaatcc agggactgtt
    18121 tttcgttatc tgccgtatct gcgtacccct gattttttgg tatacaatta cttgattcga
    18181 taatcataaa atcaagtgat tttatgattg cataattcta tgagtatgag attattataa
    18241 tgtttggcag aggtactatg tgaacaaagg ggaggggcaa atgcctaaag ttatagcatt
    18301 tttaaatggt aagggggggg tgtctaagac aacctcggca gtcaatattg ctactgctct
    18361 tgctcgtaag ggatacaaag ttgtcgttgt ggataccgat cctcagggaa gtgttagtaa
    18421 ctggtatgat gacagtaagt gtgtttttga tgtagcagaa gctacgacag aaaaagaaat
    18481 ttaccgtttg cggaaggcgc ttcctttgca cgattttatc attattgatg gtgctgcggc
    18541 gatttcggcg atatcggcag ctgctgttat ggtttctgat cttgtcatta tcccagttac
    18601 tccttcgccg cttgattttg ctgcatgtgg cgcgatattg gcagtgatag aagctcggca
    18661 ggatttacgc ccggtgattg ctcgcttttt gattactaaa aaagtacagc aaacgcatat
    18721 gctatctttg ctgaaagaat ctattgcaga aacaagcata ccagcattaa aaacaggaac
    18781 gtcgtacagg cagtcatata taaagtctat gctagatggt ggtactatat ttgatacaaa
    18841 agatagtgct gctaaaggtg aaatatcagt cattacagaa gaaatacttg gactattaaa
    18901 atgagtaaaa tgaaacttgg gaatcataag gcaacaaaca ccgctctgga tgcactaaag
    18961 aaacctgctg gagcaaccag gaaattacaa atgaatattc cagaagagtt acaccttgca
    19021 tttaagttag cttgtgtgga agatggtgtc gatatgacac aggtaaatat agaactaatt
    19081 caaaactggt tgaagagtcg taacttatag ttttgttatg atgcatatgg aggatttatg
    19141 gagtatacac caatagcgtt aagtccagga gctatgttgc ataaagggaa attcattggt
    19201 tatgtcatga agatcagatt ttccgagtgt tctggagatc atctttttta tttgagatat
    19261 gatatggttg ttgaacttgc aagagcatta gcaagaaaaa cacaccagat gtatcttaaa
    19321 gggactttta gtacagatga aagtagtcag gctacgttag aaatggaaaa ggattataag
    19381 cagcatgata tttatttaac aagtgatgaa atatcgtcac catctgtaaa taactttgtt
    19441 gcattgttag attataatgt aagggatgca tcattattat tatcactaat caaaaatgat
    19501 aattctaaaa ttgatattag tataccagaa gcagcggtgg aaatatttac aggttatatg
    19561 atgaatactg ttattaaggc agggggagaa gctttatctg aaaaacttat atcagatatt
    19621 ggagtttaat tattgctgcc aggtaaacgc gaacgctcaa aaaaggggct tttcgcccct
    19681 tttgaactaa atgttaaacg ctattcgttt tccagtggga agctcaacat ctaggcttaa
    19741 tttgcctccc atcgcttcaa cgtaacgctt taacgtcgcc agctttaaat catttccgcg
    19801 ctgttccagt tgagttacag cgggctggct gattcccatt gcatcagcaa cctgtttttg
    19861 tgaaagctgc aattcttcac gcatcatttg cagtcctgtt tccagaatca tctcatcagc
    19921 catagctttg atgatagcct gactttcagg tgattgagcc gcaattactt cttctaatgt
    19981 tctcattttt tgccctccag ttcggctaag tgagtggaaa attcttcgtc agcaatacga
    20041 atcattctgt cataaaattt tttatcatta cttttgtcgc cagcgcaaag aatgattgct
    20101 tgcctaatcg gatcaaatgc aaagaatgcc ctgattgggt gtccctcata ttgtatacgt
    20161 agttccttca tgttcttatg acgtgaccct ttcacagtat ctgcatgtgg tcgtgaaaga
    20221 gaggggccaa actcttcaag atgtctaagt tcagccagca cttttcgttt tagggctagt
    20281 tcctgttctt caaaccattc atcaaataat ctgccaaaat aaacagtcca catgtccctt
    20341 ttcctataag ttatagctta ttgatgatta tataagttac gggttattat ttcaaggaaa
    20401 acggggctat ttaacataat ggacgttatc agcaccaccg gatcacagtt cgttgtcaga
    20461 tctgaaaaat ccgctcaaaa gatcatgttt tcctgggcgt ttttcgtcgt tttttatgtt
    20521 gcttatttgt taataaaatt tcgtttcttg ttttggctga atttggatgt gaaagcctta
    20581 tatttgcaag ttatccggtg aagggaggta gccgagactg gggattgatt gttttgtaca
    20641 agttctaatg cataatgtgt acatatagta gcgttagcat agggcgtagt atgcaccaag
    20701 agcaggatat agcagatgca cttcatgaat ccctagccta tttcaatcga tattgtcgct
    20761 attcgctaaa aaggcttgct gcggattatc aggaagagat tgataactac caggatgatg
    20821 tatgggaggc tccgcagcgc gctgcgcggt taagtgcagc ggtaaaaaac tataaaacct
    20881 cacggatgat tgagtttatt ttttatatgg cgataaagct caatcttgat ttaaccccgc
    20941 tggttgttaa gcgtttatgt tcttgtcttt ttcagcgtac tggtagccag gagcttattg
    21001 ttgagatttt tggaaaaaag cagcgtgtaa atcgtagtgc tgataataca atggaacgaa
    21061 tcaatgacgt gactgaacgt tatcgtaaat cggccacaag acattggcgt aagacattat
    21121 cagatataga aaaagttaaa aaaggctatc agaaagaaat acgtgcacgg agaaaaaaga
    21181 aaagcggtaa atgaagtgaa ctcactcact acaaaggttg tggggggaga gtggatatct
    21241 tttaatcatt agtgtatctt ttttctgtct gcgggatagg gaagggcagg ctgtaaccta
    21301 tcattaacca attctctgtc gaggcaacgt tacgttgcct ctggcagcgt aacgtgatcc
    21361 tcatgtttga ggtaaacgtt atgaaagaca atcaaaacca atcactccag gtaggtgacg
    21421 caactattcg tattggtgac atttttcata cccattgggg ctatgagcaa actaatatcg
    21481 agttttatca agttgtttca ctacatggaa agaaaacagt agggcttcgg gagattgcta
    21541 gggaagtcgt aaagcacacc agttggtgta gtgcagagat tcgccctgta cctgataagt
    21601 ttattgatga agccatccat aaacgccggg ttattgcaaa atgggggtct gtccttgtac
    21661 ggttcagtga tgtaaccaat gcatggcgaa cttcaccaga agctttacac cattgttcct
    21721 ggggatacta aacgttgtga gaaggcgcag ttgcgccttc ttctttatgc gtgatagatt
    21781 ggttctgtca gatgatgcag catcaatttt gatgttctga cgtttcagca tcaaagaaca
    21841 ttcacacaac tgtcgaagca acgttacgtt gcttcggcag cgtaacgcag cttctgaata
    21901 caggagtctg gttatgacta gtgttataaa caatttatca tcgttaaacc tgatcccttg
    21961 cagatctcca tttgattctg taatgggaga acgatgctat cagtcgattg tttctgttga
    22021 tacgttcact gatttcattg ttaaggctca agctgatggt atgctgaatg aatgcaatct
    22081 tcgcgaaaat gataggtatt ctcgattatt gagaacatat cttttcagga gtatggcagt
    22141 tattcatgct gtaattgatc tacgagcagg tattgttcat ttgattgtat actcgctcgt
    22201 gacaaatgag attacggagt ttgaagccga atatttcatt tgtcagattc gtcagaatct
    22261 agaccgttat tgatctgatt ctgaactgta agggaatgct attgcattcc ctttttttct
    22321 atcagtgttg aaagtttttc gctgtattct tttcgattat gatgtaattt tagcctaacg
    22381 ttagaaaact ttttaagaac aactcttcta ttgctataga agtccttttt tgatatttct
    22441 ccacaaagat aaagaatccg ttgttgctta atgatgttat ctgtaagggt gataagggat
    22501 atcatcatca taacaacagg cgatataaga acaggtattt ttattttttt gttttcatta
    22561 tttatatggt tgtatatatc tttataattt ggtatttctg aaacagtttt ttttaagtgt
    22621 tcgtaatgcg acgaaaactc atctttttga atacggataa tttcttctgc ttttggcaat
    22681 aatgattttg caactatatg ttttatatag tgctctttgt ttttataacg ttttagattg
    22741 cttgatgtaa aaagaatttc aagatattta attgtattaa tcgcatcggt aacatgatgc
    22801 ttgtgaataa gtttttcact atgtaatttg ttgtcaattt ctccaataag aaattgatca
    22861 tttattctta aattaagttg ttttctctcc atcatatata cccacctttt tcttcaacta
    22921 gtgtcagttt atcagtcgat gcgattttgt taccactcat aaaaaacata ctgacccata
    22981 agtacaaatc tgattcatgg taaaatcctt cgtgtttttt tagtttgctt aaagtgctat
    23041 aatgttcatc cttatttttt gcataataaa gtttgacaat aaggtaacac tcttcctgtg
    23101 ttccctttga taaacaccaa tcgaatactc catcccatga gatattttct aaactaaaaa
    23161 agttctgttt tcttaatttc tggcgttgtc tgtttaaaag aatgctttgt tgagtatcgt
    23221 tgtattgctg ggcaccaaga acaggatctt cacagcgaac gccacgaaca gggcgtttgt
    23281 caaatgacag ttcccatagg ttaatatctg gtatgaactc gtaatcttcc ggtttcgcca
    23341 gacggaacat aacgctatcc tttgtctgtt gtgtgttcgg tagttctggt ttaccgtaaa
    23401 acaaaaattt tttcaacaaa ggtgtttaat atgagcgata agatccaaga aatcacgcaa
    23461 aaaattgaga aattgcagat aaaattgagc aaaattgaag aggaaaaaaa caagattcaa
    23521 tcaaagctgg ttaagttaga agaagagaaa aaatcaatac agcgcaagct gattctacag
    23581 gagaaaagag aagagcttga aatgctttta gacaaagaaa gttttgatat tttattcaat
    23641 aaatgagcat gatttttggg agaattgccc tctgattatc agagggcaat ttgtcattgg
    23701 tagtgcctgt taccgttagt tatgatcgcg aaaaacgcga tgattgttca ttacaatgcc
    23761 ctatcgttag acaggacatg tgagcgtttt atcaacaacg taagcagaat tttttgcaga
    23821 aatgatcctg catcaatact gaaaatcgtt gttgtcttac atgtgttaaa catgattttt
    23881 tagtcaattt cataacaaaa tatacctacg tttttttggg aagtcctctt actgaaccaa
    23941 cagaaagagg acgaaaaaga ggaaacatga atgtttcctc tgccatgtta ctaccgtgaa
    24001 ttttcagcta cttatctgta ctggttgcct ccagtatttt cagattcatc tacagacttc
    24061 ggctatatcg tctgtagatt tttgcgccta ctcgtccact ctcccacact caggaatgta
    24121 atttcggtgc cacccgaaat tttccagagt gcttcccacg ttagctgatc ttgtcgggat
    24181 aacccgccac tggctcagac aaactactag gctacgcctt accatttctg gctttcaggg
    24241 ggccgagatt ccaaagcacc tcccttactc ataatttgcc gtcaacacca tagccagaca
    24301 cttaagtcat ggctggttat cacttacccg aatgcgacct cttcggacgc aattacaggc
    24361 ttgagcttta cagcgatctg caaaggttgc ccctcacagt accgacgttt ccaggtttcc
    24421 cctcaacgcc ctgacacctc acgatgccct cagcagccca cctgtcggga atatgttgta
    24481 ccttctcaag caccccatat tcgggatttt cacccgttca agatcaacag ggatcacgta
    24541 gtcacctacg ttcccgtttc cgtgtcgccc agtctcacgc tttggcgtgg attgggtcgg
    24601 acaggggagt ttcacccccg aacgcccttc gtagccgtac cagcccaatt acaggcatac
    24661 ggcttcggca gtaactgtta tcagggttgg cagtcctgat aactcacctt cgtttggcag
    24721 acgaaggctt ttggcttttt tcgtctttcg acttcccaaa aatgcgtcga gagttggcag
    24781 ctcgcaacgc acgttttgtt acgtaagcga tgcttgatag tccggcgccc gaaaggctcg
    24841 catcgagccg gacatcagta taatatttaa cctgtaagcg cagcgcaagg aatctcttta
    24901 taaggtattc ccatatgttg acttctctta tgtagcggtt actacatagc ttttatgagg
    24961 atttcgatga tttaccgttt taaaaccgat tttatgcgtc agatagccat gctgttttcg
    25021 ctgggatata caaggtggtt tggtggcgaa attcctctaa accctcacta taaattcgtg
    25081 tcactaaaag cacgttttga tgaactctat gctatcaatg caacagcaca acaacgtttc
    25141 aggagaagag aaaaaggagt agcaaactgc aaatttcttg tctggtttga tgaaaaaaat
    25201 gcaactcttt tatgggtgtt acttgcaaca gaaggggatg tatacaatga agaaaaattt
    25261 tatgatggta tgaataaaaa aactcgtatt tctgtttcag gttatgaact aaaaacagtt
    25321 ccacatcgag gtagaaaacc tagcgtttca tgggctatga agaaagaaac ttatgaaaag
    25381 tggcatgcgg atataaagaa gtcgataaga acaagaaatg atgagaatat agaaaaatta
    25441 tggtattcac tcaggagggt ggcagggttt agtgagttac gtagacaggt atttaagtta
    25501 cagagatatg caatgacaga gtggaaacgt tccagaagag gtgaatatcc ttatgagaag
    25561 atttttgttg gatggttagg acgatttaaa caaagtgaaa ccatcacaga tgaagagctt
    25621 ttgttaatat cgaagtcaaa aaaagctgat atcttttagt tttatcaaca tagcgtgagg
    25681 tgcttatgca agcaaatgat gagtttcttc gcttggtttt tgaaaacata tggccctggt
    25741 ggacatatgc ttgggtttta gttttttctt tgttatgtgt gtttacattt tcgggtcatg
    25801 cagaaaaaag tggtgataag agtactctgc gtttcattat tgaagcagcc aggaagaaat
    25861 tacttgttgc atggatttta tgtactcttt tgttctttct atttgtgtac ataatagcgt
    25921 ggaaacactt tggggaagat tcacataaag catcacttta tatggagtta ttgtatgagc
    25981 ggattggtga caaatctttc tcatttggtg attattgtgg catagcattt gtactacttt
    26041 tcccctatgc ttgtcagata attaatcgcc gtcttataag accaaaacta tcatcatggc
    26101 ttcgtcgttt tcgtgtgtct cagacctcgg atactatgag tgatattcgt gttgagaaag
    26161 gtaaatattc gcctaaaaac ttcaatcctt tagattatta taaggatggt catttctttt
    26221 taggattaga tgaaaatgat aaagcaatct acgttacaga tgactatttg tctaaagtaa
    26281 atattaaaat tttaggcgca acgcaaacgg gtaaaggtgt tattcagggg gttattgcag
    26341 accaggcaat attgaaaaat tgggggttgt ggttctggga tcagaaacca gataaattta
    26401 tttactcgat tatgaaacaa cgttgtgagt cagaggggcg agaaatatat gaagttgatt
    26461 tgaatggtga aggtataggt gattatgcgc catttaagaa tggtacaaaa cgtgaaattt
    26521 tggataggtt ttttaatgcg ttttctcttg agactggcgg gactgatgca gactattaca
    26581 aaaataatgc acaggaggtt atgtactata tatatacttt ttgggaccgt tcgttaaacg
    26641 atttacaaaa attgttgtct ggtagtgatg atagaatacc ggaggaaaaa caggaatgga
    26701 tagctaaaaa tggagctaat attcgaacgc agcttaataa atggttagag cttccttgtc
    26761 tatctcccgt tgatggtcag ggattaaatg taactgaact ggttaagtca ggtgcggtta
    26821 tttatgtaaa aggtagcaca aaagataagg ttgtcagggc tgtcttaaaa tcaatgttgc
    26881 gtgagtggtc tgcggctgtt attcgtgaac aaccaaaaaa tcatgtgctg gggataattg
    26941 atgaggcccg ttttgttatc tcgtcagagg ttgctgatag tctggcaact atattatcct
    27001 caaatgcaag tttgtctatt gcatatcaag agagagatga ccttttaaat ataccggatg
    27061 aaaaaccgca gattgctcag tcaataaaaa aagggacgga aacaaatacc aatttgacac
    27121 ttgtttatcg ttgtaatgac gagacggctg aatgggttgc caaaaattct ggtacaactg
    27181 cgaagagtct gacaaaactt gaagaagtcg aaactgacgg ttatggcgcg gaaacatgga
    27241 agggacgacg aatgattgga caggaagagg attactatat accagtaaat acggttcttg
    27301 cagttgaaga acgagttggt attatgcaga ctatgtttga actcagtcgg gttttattta
    27361 catgctgggt tcctgttcaa cgtttttata cacttccggc ccgccctcaa acggagcagg
    27421 ataatgttca ggattgtata aagaatgatg gttcaatttc tccgagtgat gaggattact
    27481 ttaatcctga catgattagt gatgaagagc tagcgatgat aaataaaaca gtatcgtcag
    27541 acagtaaata aaataaatct ggcatctagc tgatgccaga ttttttagtt aataatatgg
    27601 tgtacatatg gataaaacga caaaaacata tccttttggt gaaattgagt tttttgacca
    27661 gttagaggaa catgcatggg accagattca tgatggtatg ctaccaatta tggatttgta
    27721 tcttgatccg acagtaaccg atatatttat aaacaggtat gacaatatat atacatctgt
    27781 caatggcaag tatgtaaaga ccgacagttc cttttccagt gaacgggcac ttaaagcctg
    27841 gattgatcaa atcgcaacgg tgttgaggca gccattttca acgtcaggaa actataaata
    27901 tggtgatgtc attgagcctg tacttgatgc ccgatttccc gatggttccc ggttgatgtg
    27961 tacagacccg gtgatttcac cgcagggttc tacggtaagt cttcgtaaag tacctaagca
    28021 aatactggaa gaaaaagatt ttataaattc cggtatgttg acgagagata ttcttgatta
    28081 tctcattagt gttatacaaa aacggaaaaa ttttattgtt gctggtaata ctggttctgg
    28141 caaaacatca cttttacgct tgctcgccag gtatattgat acgatggagc gtgttatcac
    28201 cgccgaagac actcaagaac ttcatataca caggtatttt ccgttaggga ttgctctgga
    28261 agctgcacat cgtaaagatg tgaatgcgga tcttccttct ctggttcacc tgactatgcg
    28321 tggtaatccc gatcgtgtat gggttgggga ggtaagaacg gcagaggcta tagctgctta
    28381 ttacatggtt ctggcaagtg gaactatagg taatgctaca actctgcact ccgttacccc
    28441 tatgggggca atacgcaaaa tgacttggct tatgtcaagc tatctcagta tcgattttca
    28501 gatagctcag gatttaatta tgtcagaggt tgacgtgatt attcagtgcc ggagaacatc
    28561 aaagcatgga agaagaatta cagatatcgt cgaaatacgt gaagggaaaa ttgttcctat
    28621 attcaagttt gatgaagagc aagaagtaca tgtcaggttt gacaaaaaat gaacatttag
    28681 cattatatgc ttatatgctt atatgcttat atgcttatat gcttatatgc ttatatgctt
    28741 atatgcttat atcattgtgt ttgtgtgaaa tattgctgta acatcgacgg tctacgacca
    28801 cctaccacct gaatagctgt aggttccgtg cggtcaggct tagcaggagg ctgacgcggt
    28861 tcctggcgac atgaaactcc ctggttaggg gtatcggcgc gacctggcat ctgtgactct
    28921 atgaagccat ttttcgcgcc ttccatgccg ctaaagcggc atattccaca cttctagatc
    28981 cggggttttg ggtatatgct atgtttatat gcataattta tgtggggggg cttgttatga
    29041 gaacaaatgt ggcagtaaaa aaacgtagta taaacgtata cttaaatgca gggttacttg
    29101 aagaagcaaa agatcttgat ctgaatgttt ctgctatctc taacaaagct ctcgaaaaag
    29161 cggtaaggga gcgtaagcgt gaacgctgga tagaagaaaa ccgtgctggc attgaggcat
    29221 taaaccgttt tgtagaagat accgggattt tttcagatga tgaaaatttt ggggtaattt
    29281 agtgaaacaa ttttctgtct acaagaacaa atcgcgaaat aaacaggcgt acccctattt
    29341 tattgatata caggcagaga tgcttgcaca ccttaacacc cggttggtga tgcctttaac
    29401 gccaaaagat aattcaaact cgcaggtaaa gacgttaacg ccagtaataa acatcaacca
    29461 ggtagattat gtggttctga ctactatgat aacgacaacg gatgcaaaaa atctgaactc
    29521 tgataatgtc gttatggatg cttcatattt acgagatcaa ctggtttctg caattgacat
    29581 gatgattctg ggtatttaat ttttgcaggg tagtaaatag taaaaaatat cgctgtaaca
    29641 tcgacggtct acgaccacct accacctgaa tagctgtagg ttccgtgcgg tcaggcttag
    29701 cagggggctg acgcggttcc tggcgacatg aaactccctg gttaggggta tcggcgcgac
    29761 ctggcatctg tgactctatg aaaccatttt tcgcgccttc catgccgcta aagcggcata
    29821 ttcca
//
