LOCUS       NZ_CP045256            24983 bp    DNA     circular CON 24-JUL-2023
DEFINITION  Proteus mirabilis strain L90-1 plasmid pL901, complete sequence.
ACCESSION   NZ_CP045256
VERSION     NZ_CP045256.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN13037561
            Assembly: GCF_013343255.1
KEYWORDS    RefSeq.
SOURCE      Proteus mirabilis
  ORGANISM  Proteus mirabilis
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Proteus.
REFERENCE   1  (bases 1 to 24983)
  AUTHORS   Liu,N., Gou,J., Zheng,B. and Guo,X.
  TITLE     Dissemination of Multidrug-Resistant Proteus mirabilis clones
            Carrying blaKPC-2 and blaTEM-1 gene in a Teaching Hospital
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24983)
  AUTHORS   Liu,N., Gou,J., Zheng,B. and Guo,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2019) State Key Laboratory for the Diagnosis and
            Treatment of Infectious Diseases, The First Affiliated Hospital of
            Zhejiang University, 79 Qingchun Road, Shangcheng District,
            Hangzhou, Hangzhou, Zhejiang 310000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: Unicycler
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/24/2023 04:13:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,060
            CDSs (total)                      :: 3,951
            Genes (coding)                    :: 3,863
            CDSs (with protein)               :: 3,863
            Genes (RNA)                       :: 109
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 27 of 88
            Pseudo Genes (incomplete)         :: 60 of 88
            Pseudo Genes (internal stop)      :: 18 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045256.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24983
                     /organism="Proteus mirabilis"
                     /mol_type="genomic DNA"
                     /strain="L90-1"
                     /isolation_source="stool"
                     /host="Homosapiens"
                     /db_xref="taxon:584"
                     /plasmid="pL901"
                     /geo_loc_name="China:Hangzhou"
                     /lat_lon="30.3 N 120.2 E"
                     /collection_date="2016-05-17"
                     /collected_by="Tao Lv"
     gene            1..720
                     /locus_tag="GCE56_RS00215"
                     /old_locus_tag="GCE56_00210"
     CDS             1..720
                     /locus_tag="GCE56_RS00215"
                     /old_locus_tag="GCE56_00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561120.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001749982.1"
                     /translation="MDKLLNKKIKVKQSNELTEAAYYLSLKAKRVLWLCLMQTYFTASV
                     SEDDDEMAVLGDSTFKVKVADYEQIFQVSRNQAIKDVKEGVFELSRSAVIFYPKEGSFD
                     CVARPWLTEAGSRSARGIWEIEFNHKLLRYIYGLTNQFTTYSLRDCGSLRNPRTIRLYE
                     SLAQFKSSGLWVTTHAWLNDRFLLPESQQKNLAELKRSFLDPALKQINEKTPLLAKYSI
                     DDSGKFLFSIIDKQNPV"
                     /name="replication initiation protein"
     gene            complement(1450..2019)
                     /locus_tag="GCE56_RS00220"
                     /old_locus_tag="GCE56_00220"
     CDS             complement(1450..2019)
                     /locus_tag="GCE56_RS00220"
                     /old_locus_tag="GCE56_00220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749988.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001749988.1"
                     /translation="MKIGYARKSTHLQDVAHQVDELTKAGCEQIYQDQTSRSGPKRDKK
                     GAPELENCLKALREGDTLVVWALDRLGGSLGQVITLLDDLKKRGITFIAIKDRIDTNAP
                     VIGEIYTHLMAIFSSFERNRNIERTRSGLAAARARGRVGGRKPSLSEEDVKQIRILLAD
                     PEMTVGAVAKRFNVSRMTIYRYTTKS"
                     /name="recombinase family protein"
     gene            2348..3052
                     /locus_tag="GCE56_RS00225"
                     /old_locus_tag="GCE56_00230"
     CDS             2348..3052
                     /locus_tag="GCE56_RS00225"
                     /old_locus_tag="GCE56_00230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <3105..3497
                     /locus_tag="GCE56_RS00230"
                     /old_locus_tag="GCE56_00235"
                     /pseudo=""
     CDS             <3105..3497
                     /locus_tag="GCE56_RS00230"
                     /old_locus_tag="GCE56_00235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            3620..4600
                     /locus_tag="GCE56_RS00235"
                     /old_locus_tag="GCE56_00240"
     CDS             3620..4600
                     /locus_tag="GCE56_RS00235"
                     /old_locus_tag="GCE56_00240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013213985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS481-like element ISKpn27 family transposase"
                     /protein_id="WP_013213985.1"
                     /translation="MTQALHSQARTTHLIREEIRNSTLPQAELARMYNVTRQTIRKWQN
                     RESPEDKSHAPNKMYTTLTPEQELIVVELRKTLLLPTDDLLAVTREFINPAVSRAGLGR
                     CLRRHGVSDLRNLVEQEGTAPATKKTFKDYEPGFVHIDIKYLPQMPDETARRYLFVAID
                     RATRWVFIELYADQTDGSSGDFLNKVQQACPVKIVKLLTDNGSQFTDRFTAGGKKKEPS
                     GTHVFDRLCKQLGIEHRLIPPRHPQTNGMVERFNGRISDIVNQTRFGSAAELESTLRNY
                     VKIYNHSIPQRALQHKTPVQALKEWHEKRPELFRKRVYNQPGLDI"
                     /name="IS481-like element ISKpn27 family transposase"
     gene            4876..5757
                     /locus_tag="GCE56_RS00240"
                     /old_locus_tag="GCE56_00245"
     CDS             4876..5757
                     /locus_tag="GCE56_RS00240"
                     /old_locus_tag="GCE56_00245"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015256839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /protein_id="WP_004199234.1"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIG
                     VYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
                     SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
                     WELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRA
                     AVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAA
                     RLALEGLGVNGQ"
                     /name="carbapenem-hydrolyzing class A beta-lactamase KPC-2"
     gene            complement(6007..>6888)
                     /locus_tag="GCE56_RS00245"
                     /old_locus_tag="GCE56_00250"
                     /pseudo=""
     CDS             complement(6007..>6888)
                     /locus_tag="GCE56_RS00245"
                     /old_locus_tag="GCE56_00250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISKpn6 family transposase"
                     /name="IS1182-like element ISKpn6 family transposase"
     gene            complement(6992..7288)
                     /locus_tag="GCE56_RS00255"
                     /old_locus_tag="GCE56_00255"
     CDS             complement(6992..7288)
                     /locus_tag="GCE56_RS00255"
                     /old_locus_tag="GCE56_00255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="WP_013213987.1"
                     /translation="MIRPETLRPFAEDWQAPTADEIKEVLELIRQRKGLSKPLSGVDVA
                     DLVGLPGERGSGKGTRTFRRWVSKTNPSPIAYGAWSILAHLAGFGAIWDADRD"
                     /name="transcriptional regulator"
     gene            complement(7334..7489)
                     /locus_tag="GCE56_RS00260"
     CDS             complement(7334..7489)
                     /locus_tag="GCE56_RS00260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_013213988.1"
                     /translation="MNTDIVSLAKHIGDALTARRPVHMPRMKMRELGLLLIELKAYREA
                     AATVTH"
                     /name="hypothetical protein"
     gene            complement(7617..8042)
                     /locus_tag="GCE56_RS00265"
                     /old_locus_tag="GCE56_00260"
     CDS             complement(7617..8042)
                     /locus_tag="GCE56_RS00265"
                     /old_locus_tag="GCE56_00260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="WP_013213989.1"
                     /translation="MMQTELNPLICSLVATPRRMAAMPRYVGRFYVVFESMLYQQMKGL
                     CREYRGAYWLMWELSNGGFYMAPGRRDEMLNIEAMNYFSGQMSADAAGITACLYLYSHL
                     SFHTEGADQERFSRLYHSLRDWACEHDEKEAILAAID"
                     /name="antirestriction protein"
     gene            complement(8153..8431)
                     /locus_tag="GCE56_RS00270"
                     /old_locus_tag="GCE56_00265"
     CDS             complement(8153..8431)
                     /locus_tag="GCE56_RS00270"
                     /old_locus_tag="GCE56_00265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_013213990.1"
                     /translation="MIHTANRTFHQLYREWIRERREHMHNVLTWERDRYGARLVGLFYR
                     YCKVANPFPRCTLNTRINYRAHAVNLPDWPARSLELNKMWLSWREKK"
                     /name="hypothetical protein"
     gene            complement(8965..>9582)
                     /locus_tag="GCE56_RS00275"
                     /old_locus_tag="GCE56_00270"
                     /pseudo=""
     CDS             complement(8965..>9582)
                     /locus_tag="GCE56_RS00275"
                     /old_locus_tag="GCE56_00270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017413030.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            9974..10534
                     /locus_tag="GCE56_RS00280"
                     /old_locus_tag="GCE56_00275"
     CDS             9974..10534
                     /locus_tag="GCE56_RS00280"
                     /old_locus_tag="GCE56_00275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220837.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001161490.1"
                     /translation="MQGHRIGYVRVSSFDQNPERQLEQTQVSKVFTDKASGKDTQRPQL
                     EALLSFVREGDTVVVHSMDRLARNLDDLRRLVQKLTQRGVRIEFLKEGLVFTGEDSPMA
                     NLMLSVMGAFAEFERALIRERQREGIALAKQRGAYRGRKKALSDEQAATLRQRATAGEP
                     KAQLAREFNISRETLYQYLRTDD"
                     /name="recombinase family protein"
     gene            10538..13485
                     /locus_tag="GCE56_RS00285"
                     /old_locus_tag="GCE56_00280"
                     /pseudo=""
     CDS             10538..13485
                     /locus_tag="GCE56_RS00285"
                     /old_locus_tag="GCE56_00280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /name="Tn3-like element TnAs1 family transposase"
     gene            complement(<13518..13751)
                     /locus_tag="GCE56_RS00290"
                     /old_locus_tag="GCE56_00285"
                     /pseudo=""
     CDS             complement(<13518..13751)
                     /locus_tag="GCE56_RS00290"
                     /old_locus_tag="GCE56_00285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            14277..14645
                     /gene="stbA"
                     /locus_tag="GCE56_RS20335"
     CDS             14277..14645
                     /gene="stbA"
                     /locus_tag="GCE56_RS20335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbA"
                     /protein_id="WP_227641845.1"
                     /translation="MKPKSIRAALQLMLPEIEEMLSLGVSREEIYKAVSERFGLEGVNV
                     RSFDTSLYRARQIRKNGMHNTHERMPNNDDSVLHNTQTPPEPEPQGSEKKESPGIIDKE
                     FFNKISEDFDPKMFNKKF"
                     /name="stbA"
     gene            14654..15370
                     /gene="stbB"
                     /locus_tag="GCE56_RS00300"
                     /old_locus_tag="GCE56_00295"
     CDS             14654..15370
                     /gene="stbB"
                     /locus_tag="GCE56_RS00300"
                     /old_locus_tag="GCE56_00295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="StbB family protein"
                     /protein_id="WP_001749973.1"
                     /translation="MKVAVINYSGSVGKTLISSYLLAPRLTGAKFYAVETINQSASDLG
                     IENVSIFKGDDFSRLIEDIVFEDAGIIDIGASNVEAFLMAMSRFDSGANEFDKYVIPVT
                     PDNKAIDESLKTAHTLSKAGVSSDKIIFVPNRISPDSEVEDVLAPVFEFVKRTKVGKIS
                     KKSVIYNSEVFEYLAYHRISFEALTAEDPEEFKARAKQTTDADERKKLARRYTYMKQAI
                     PVKANLDKAYAALMGE"
                     /name="stbB"
     gene            15372..15740
                     /gene="stbC"
                     /locus_tag="GCE56_RS00305"
                     /old_locus_tag="GCE56_00300"
     CDS             15372..15740
                     /gene="stbC"
                     /locus_tag="GCE56_RS00305"
                     /old_locus_tag="GCE56_00300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbC"
                     /protein_id="WP_000414913.1"
                     /translation="MEKQPDKFEVLMDWFLGDAKEITASQKEMTEILSALSEKLAKDTE
                     SLGETADSLKRTLVENQRSISLAISDDAKAREEFLTKFRRAQASRAETLTRQILFITAG
                     CTIVGAAVGAAIAIILLR"
                     /name="stbC"
     gene            15922..16266
                     /locus_tag="GCE56_RS00310"
                     /old_locus_tag="GCE56_00305"
     CDS             15922..16266
                     /locus_tag="GCE56_RS00310"
                     /old_locus_tag="GCE56_00305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000999874.1"
                     /translation="MNDRQREQARIRQARRRARLKEEGASVTVTLTKQEEAMLQELCRV
                     RRPGRTAYSTNEFFQLLLIRNWQQWQEQKAQLGKCQACGKLKAEGGCGGERQSETFNCW
                     LAVEANELNV"
                     /name="hypothetical protein"
     gene            complement(16377..16697)
                     /gene="ccgAII"
                     /locus_tag="GCE56_RS00315"
                     /old_locus_tag="GCE56_00310"
     CDS             complement(16377..16697)
                     /gene="ccgAII"
                     /locus_tag="GCE56_RS00315"
                     /old_locus_tag="GCE56_00310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000211833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CcgAII"
                     /protein_id="WP_001749971.1"
                     /translation="MTTQTLEQTLEDFRRQCESFAREQQPRCGLIYELYQRRLSAVIDG
                     YLAGVPAEYREELIAVARREFDYLTQDEIAEEIRQDRENDYCSHGIERNCCPLGCGDLD
                     DY"
                     /name="ccgAII"
     gene            complement(16752..16931)
                     /gene="ccgAI"
                     /locus_tag="GCE56_RS00320"
                     /old_locus_tag="GCE56_00315"
     CDS             complement(16752..16931)
                     /gene="ccgAI"
                     /locus_tag="GCE56_RS00320"
                     /old_locus_tag="GCE56_00315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CcgAI"
                     /protein_id="WP_000214483.1"
                     /translation="MTTVTTPSQLKKEVESQKELLLRACLEAFNQLPNQRLQGAFTSTY
                     ALAAKLDQLLQQTK"
                     /name="ccgAI"
     gene            complement(17658..18167)
                     /locus_tag="GCE56_RS00325"
                     /old_locus_tag="GCE56_00320"
     CDS             complement(17658..18167)
                     /locus_tag="GCE56_RS00325"
                     /old_locus_tag="GCE56_00320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="WP_000129958.1"
                     /translation="MTDITTPSVYVGTYHKYNCGSIAGAWLDLTDFDSSEEFYERCREL
                     HANEADPEFMFQDWEGIPSDMASECHINWDFINGFKQAREEGNEAAFVAFVDLFNSTDF
                     DLFRDAYMGEAKDEETFAEEYLNDSGLLNEIPESVARYFDIVAYARDLFIGDFSLHDGH
                     VFNMTC"
                     /name="antirestriction protein ArdA"
     gene            complement(19054..19293)
                     /locus_tag="GCE56_RS00330"
                     /old_locus_tag="GCE56_00325"
     CDS             complement(19054..19293)
                     /locus_tag="GCE56_RS00330"
                     /old_locus_tag="GCE56_00325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000932975.1"
                     /translation="MLNKTENNTNISSINPCSTESLIAVTGNDGETHIIQRELISHSVE
                     GHEATIIHLVTGKSIRVSLSSEILAKKLGITVSE"
                     /name="hypothetical protein"
     gene            complement(19303..19707)
                     /gene="ardR"
                     /locus_tag="GCE56_RS00335"
                     /old_locus_tag="GCE56_00330"
     CDS             complement(19303..19707)
                     /gene="ardR"
                     /locus_tag="GCE56_RS00335"
                     /old_locus_tag="GCE56_00330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdAB regulator ArdR"
                     /protein_id="WP_000881513.1"
                     /translation="MLATLQHPTAWQLPDRLMLLELLMFDYRNSDQERYGQQIYHHYRK
                     QGNHRWDTSVHQDSGGQYAIIFRHSFSKKQADGVKRTMIRDETVIRAGTAQELTEATFP
                     DFQDSDILKASDFFKSLIQRKAADVTQTDI"
                     /name="ardR"
     gene            complement(19765..20190)
                     /gene="ardB"
                     /locus_tag="GCE56_RS00340"
                     /old_locus_tag="GCE56_00335"
     CDS             complement(19765..20190)
                     /gene="ardB"
                     /locus_tag="GCE56_RS00340"
                     /old_locus_tag="GCE56_00335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdB"
                     /protein_id="WP_000447669.1"
                     /translation="METIEITARYISENARMNFMPAAFRGAFFSADHFIQSFLNRYAKD
                     YQGGYWEYLQASNGAFFMEAPQPLWLSLPNYFEGECSAREVGIIVCLYAYSYFCGLAYE
                     EGKAELNETMANRYHLLREYVNTLENESQNRIYRAID"
                     /name="ardB"
     gene            20605..21045
                     /gene="mucA"
                     /locus_tag="GCE56_RS00345"
                     /old_locus_tag="GCE56_00345"
     CDS             20605..21045
                     /gene="mucA"
                     /locus_tag="GCE56_RS00345"
                     /old_locus_tag="GCE56_00345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_107685442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit MucA"
                     /protein_id="WP_000861760.1"
                     /translation="MKVDIFESSGASRVHSIPFYLQRISAGFPSPAQGYEKQELNLHEY
                     CVRHPSATYFLRVSGSSMEDGRIHDGDVLVVDRSLTASHGSIVVACIHNEFTVKRLLLR
                     PRPCLMPMNKDFPVYYIDPDNESVEIWGVVTHSLIEHPVCLR"
                     /name="mucA"
     gene            21033..>22046
                     /gene="mucB"
                     /locus_tag="GCE56_RS00350"
                     /old_locus_tag="GCE56_00350"
                     /pseudo=""
     CDS             21033..>22046
                     /gene="mucB"
                     /locus_tag="GCE56_RS00350"
                     /old_locus_tag="GCE56_00350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V subunit
                     MucB"
                     /name="mucB"
     gene            complement(22099..22803)
                     /locus_tag="GCE56_RS00355"
                     /old_locus_tag="GCE56_00360"
     CDS             complement(22099..22803)
                     /locus_tag="GCE56_RS00355"
                     /old_locus_tag="GCE56_00360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <22869..23126
                     /locus_tag="GCE56_RS00360"
                     /old_locus_tag="GCE56_00365"
                     /pseudo=""
     CDS             <22869..23126
                     /locus_tag="GCE56_RS00360"
                     /old_locus_tag="GCE56_00365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
                     /name="DUF4113 domain-containing protein"
     gene            23277..24068
                     /locus_tag="GCE56_RS00365"
                     /old_locus_tag="GCE56_00370"
     CDS             23277..24068
                     /locus_tag="GCE56_RS00365"
                     /old_locus_tag="GCE56_00370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="WP_001452808.1"
                     /translation="MNLPTPETYDELQRAYDFFNEKLFSNELPPCLITLQREKRTYGYC
                     SFKRFVGRESGYTVDEIAMNPVYFSIRTIKATLSTLVHEMVHQWQFHFGEPGRRGYHNK
                     QWAARMERVGLMPSDTGEPGGRKVGQSMTHYIIAGGPFDMACDELLTGHFRLSWMDRFP
                     PYQPKPGAVLSPTGKGYIDDEEDDSEHEQEVEEGRDPVELDDEIIEAMRFVTPPPEAPV
                     NKTNREKYSCPVCHINLWGKPGIVVYCGGEHCNKAALVVLK"
                     /name="SprT-like domain-containing protein"
     gene            complement(24083..24424)
                     /gene="ardK"
                     /locus_tag="GCE56_RS00370"
                     /old_locus_tag="GCE56_00375"
     CDS             complement(24083..24424)
                     /gene="ardK"
                     /locus_tag="GCE56_RS00370"
                     /old_locus_tag="GCE56_00375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdAB regulator ArdK"
                     /protein_id="WP_000057569.1"
                     /translation="MAQKNRISETEWKQLLPQMASFAHITTDIGYSVLVKGEKSSDVAT
                     RVGRSKQNISSTVKRIWDLYQNTTLKAENGEPLKLVQVWIPASLAETVLKEAAKYSINN
                     ITTSEMEKK"
                     /name="ardK"
     ARG             4877..5754
                     /name="blaKPC-2"
                     /gene="blaKPC-2"
                     /gene_name="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(13849..14115)
                     /name="MOBF"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="87.546"
                     /coverage="100.0"
                     /evalue="4.2000000000000003e-81"
     Typing          2..720
                     /name="IncN"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.583"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(8966..9525)
                     /name="IncU"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atggataagt tgctgaacaa aaagataaaa gttaagcagt ctaacgagct taccgaagct
       61 gcttactacc tctcgctaaa agcaaagcgc gttctctggt tatgtcttat gcagacgtat
      121 ttcacagctt cagtaagcga agatgatgat gagatggctg tactcggtga ctctactttc
      181 aaagtaaagg tggctgacta tgagcaaatt tttcaggtaa gccgtaacca ggctatcaag
      241 gatgttaaag aaggcgtgtt tgagttaagc cgttctgcgg taatctttta cccgaaagaa
      301 ggaagttttg actgcgtcgc gcgcccctgg ctaacagagg ctggcagccg atcagctcgt
      361 ggtatctggg aaatcgaatt taaccataaa ctcctgcggt acatttacgg cctgacgaac
      421 cagttcacca cctactcgct ccgcgattgt ggcagtcttc gaaatccacg gacgatccgc
      481 ctttatgaaa gtcttgctca attcaaatct tcaggcttat gggttactac tcatgcttgg
      541 ttaaatgacc gtttcctttt gccggaatcc caacagaaga acttggcaga gttgaaacga
      601 tctttccttg atcctgcact caagcagata aatgagaaaa cacctttact tgctaagtat
      661 agtattgatg attcaggaaa atttctgttc tcaataattg ataagcaaaa tcccgtctga
      721 cataaatcag cacacatgag cctgtcattt gacaaatttt tgtcatgaag atgggcgaat
      781 ttccacacag caccggcgcc cggcaaggtg ggcggattcc cacacggcac cggcgcccgg
      841 caaggtgggc ggattcccac acggcaccgg cgcccggcaa ggtgggcgga tttccacacg
      901 gcaccggcac ccggcaaggt gggcggattc ccacacggca ccggcgcccg gcaaggtggg
      961 cggatttcca cacagcaccg gcgcccggca aggtgggtgg attcccacac ggcaccggcg
     1021 cccggtaagg tgggcggatt tccacacgac agcggcgccc ggcaagatgg gcggattccc
     1081 atatcgacat gtatgtagct tgtgttatcc gtggattgtg cagctcagcg ggtcgctggt
     1141 cgtatggcgt agtgtccccc gtaaccggcc gcgtgcggcc gctaactcgc agtacggcgc
     1201 cgcgacccga aggcgggccg ccgttcccgc gcgcaggcgc gcggcgccca ctgcgcaccc
     1261 ccgtggggga catacggcag ctgtgtggcg gtgagcggga ttagggcttt gcagggaggg
     1321 ggctgggtcg ggcgatacgt tcagcattgc ggtttccggc gatttgcggc cggtgcccgt
     1381 ttaactccgg cgtggtcgcc ttccatgccc tgacggcata agaaaataaa accgccatgc
     1441 tgcggtcatt catgattttg tggtgtagcg ataaatagtc atgcgagaaa cgttgaagcg
     1501 cttagcaact gcaccaactg tcatttcagg atcagcaagt aagattctaa tttgtttaac
     1561 atcttcttca gaaagtgacg gttttctccc tcccacacgg ccccttgcgc gtgcagctgc
     1621 aaggcctgag cgcgttcttt caatattgcg gttgcgttca aagctagaga atatcgccat
     1681 cagatgagta tagatttccc ctataactgg cgcatttgtg tctattctgt ccttgatggc
     1741 tatgaaagtt attccgcgtt tcttcaggtc gtcgagtaaa gtaatgactt gacccaatga
     1801 accgccgagc cgatctagtg cccaaactac tagggtatct ccctcgcgca atgctttcag
     1861 gcagttctcc agttccggcg cacctttttt gtcgcgcttt gggccgctac gtgaggtctg
     1921 atcctgatag atttgctcac atccagcttt tgttagttcg tcaacctggt gcgccacatc
     1981 ctgaagatgc gtagatttac gtgcatagcc gattttcatt cttttctcgc taattagtta
     2041 tggggttatt gttatgttga tacagtaacg agttttgtta catgagggga gtcatttttc
     2101 gggagaagtc aggacttttc aagactgtca caaaaaccat cgtttttgat acattaattt
     2161 aaccaatagg ttgcagatca aatcgcctgt aacagccttt ctggctgttt gtcgttttca
     2221 gaagacggct gcactgaacg tcagaagccg actgcactat agcagcggag gggttggatc
     2281 catcggcact gttgcaaata gtcggtggtg ataaacttat catccccttt tgctgatgga
     2341 gctgcacatg aacccattca aaggccggca ttttcagcgt gacatcattc tgtgggccgt
     2401 acgctggtac tgcaaatacg gcatcagtta ccgtgagctg caggagatgc tggctgaacg
     2461 cggagtgaat gtcgatcact ccacgattta ccgctgggtt cagcgttatg cgcctgaaat
     2521 ggaaaaacgg ctgcgctggt actggcgtaa cccttccgat ctttgcccgt ggcacatgga
     2581 tgaaacctac gtgaaggtca atggccgctg ggcgtatctg taccgggccg tcgacagccg
     2641 gggccgcact gtcgattttt atctctcctc ccgtcgtaac agcaaagctg cataccggtt
     2701 tctgggtaaa atcctcaaca acgtgaagaa gtggcagatc ccgcgattca tcaacacgga
     2761 taaagcgccc gcctatggtc gcgcgcttgc tctgctcaaa cgcgaaggcc ggtgcccgtc
     2821 tgacgttgaa caccgacaga ttaagtaccg gaacaacgtg attgaatgcg atcatggcaa
     2881 actgaaacgg ataatcggcg ccacgctggg atttaaatcc atgaagacgg cttacgccac
     2941 catcaaaggt attgaggtga tgcgtgcact acgcaaaggc caggcctcag cattttatta
     3001 tggtgatccc ctgggcgaaa tgcgcctggt aagcagagtt tttgaaatgt aaggcctttg
     3061 aataagacaa aaggctgcct catcgctaac tttgcaacag tgccgaggaa ggtgatgtca
     3121 ttctggtgaa gaagctcgac cgtcttggcc gcgacaccgc cgacatgatc caactgataa
     3181 aagagtttga tgctcagggt gtcgcggttc ggtttattga cgacgggatc agtaccgacg
     3241 gtgatatggg gcaaatggtg gtcaccatcc tgtcggctgt ggcacaagct gaacgccgga
     3301 ggatcctaga gcgcacgaat gagggccgac aggaagcaaa gctgaaagga atcaaatttg
     3361 gccgcaggcg taccgtggac aggaacgtcg tgctgacgct tcatcagaag ggcactggtg
     3421 caacggaaat tgctcatcag ctcagtattg cccgctccac ggtttataaa attcttgaag
     3481 acgaaagggc ctcgtgatac gcctattttt ataggtgtct ggactcgtgg gatcatgtac
     3541 ccatgcgtag ctggccgctc ttcaaggcca gacacgtttt gcgtacactg ttccaatccg
     3601 actcttcact ggcaactcga tgacccaggc actgcacagc caagcccgta ctacccacct
     3661 gatccgtgag gaaatcagga actcgacgct cccgcaggcc gaactggcca ggatgtacaa
     3721 cgtcacccgc caaaccatcc gaaagtggca aaaccgcgag tctcctgaag acaagtcgca
     3781 tgcgccgaac aagatgtaca cgacgctcac gcccgagcag gagctcatcg tggtggagct
     3841 gcgcaagacg ttgctgctgc ccacggacga cctgctggcg gtcacgcgcg agttcatcaa
     3901 tccagccgtc tcgcgtgccg gcctgggacg ttgcctgcgc cgccacggtg tctcggatct
     3961 acgtaacctg gtcgagcagg aaggcactgc gcccgccacg aaaaagacct tcaaggacta
     4021 cgagccgggc tttgtgcaca tcgacatcaa gtacctgccg cagatgcccg acgagacggc
     4081 aaggcgctat ctcttcgttg ccatcgaccg tgctacgcgc tgggtcttca tcgagctcta
     4141 tgccgaccag accgatggca gcagtggcga cttcctcaac aaagtccagc aagcctgtcc
     4201 cgtcaagatc gtcaagcttc tgaccgacaa cggcagccag ttcaccgacc gcttcacggc
     4261 tggcggcaag aagaaggaac ccagcggcac acacgtgttc gaccgcctgt gcaagcagct
     4321 cggcatcgag caccggctca tcccgcctcg tcatccgcag accaacggca tggtggagcg
     4381 cttcaacggt cgtatcagcg acatcgtcaa ccagacccgt tttggttcag ctgccgaact
     4441 ggaatcgacg ctgcgcaatt acgtcaagat ctacaaccac agcattccgc aacgcgcgct
     4501 ccaacacaaa acacccgttc aggcgctcaa ggaatggcat gaaaaacgcc ctgaattgtt
     4561 caggaaacgc gtgtataacc agccgggtct tgacatatag gttaatgtca tgataataat
     4621 ggtttcttag acgtcaggtg gcacttttcg gggaaatgtg cgcggaaccc ctatttgttt
     4681 atttttctaa atacattcaa atatgtatcc gctcatgaga caataaccct gataaatgct
     4741 tcaataatat tgaaaaatga cttcttaacg tgagttttcg ttccactgag cgtcagaccc
     4801 ctaatcccag ctgtagcggc ctgattacat ccggccgcta cacctagctc caccttcaaa
     4861 caaggaatat cgttgatgtc actgtatcgc cgtctagttc tgctgtcttg tctctcatgg
     4921 ccgctggctg gcttttctgc caccgcgctg accaacctcg tcgcggaacc attcgctaaa
     4981 ctcgaacagg actttggcgg ctccatcggt gtgtacgcga tggataccgg ctcaggcgca
     5041 actgtaagtt accgcgctga ggagcgcttc ccactgtgca gctcattcaa gggctttctt
     5101 gctgccgctg tgctggctcg cagccagcag caggccggct tgctggacac acccatccgt
     5161 tacggcaaaa atgcgctggt tccgtggtca cccatctcgg aaaaatatct gacaacaggc
     5221 atgacggtgg cggagctgtc cgcggccgcc gtgcaataca gtgataacgc cgccgccaat
     5281 ttgttgctga aggagttggg cggcccggcc gggctgacgg ccttcatgcg ctctatcggc
     5341 gataccacgt tccgtctgga ccgctgggag ctggagctga actccgccat cccaggcgat
     5401 gcgcgcgata cctcatcgcc gcgcgccgtg acggaaagct tacaaaaact gacactgggc
     5461 tctgcactgg ctgcgccgca gcggcagcag tttgttgatt ggctaaaggg aaacacgacc
     5521 ggcaaccacc gcatccgcgc ggcggtgccg gcagactggg cagtcggaga caaaaccgga
     5581 acctgcggag tgtatggcac ggcaaatgac tatgccgtcg tctggcccac tgggcgcgca
     5641 cctattgtgt tggccgtcta cacccgggcg cctaacaagg atgacaagca cagcgaggcc
     5701 gtcatcgccg ctgcggctag actcgcgctc gagggattgg gcgtcaacgg gcagtaaggc
     5761 tctgaaaatc atctattggc ccaccaccgc cgcccttgcg ggcggcatgg attaccaacc
     5821 actgtcacat ttaggctagg agtctgcgcg gcagagccgt gtgaccggtt ttctgtagag
     5881 cactgacgat ggcggcggcg ctctctgcaa ttggcaaggc gtcggcgcca aggataccaa
     5941 tcttgcggcg cgcggcgtgt tatgacgact ggggtgcatt tgagccgccc catttaacct
     6001 tcgccctcac agatacgcca ttcgcctcag atttagcgcc atgcagacga gcttccactc
     6061 ggcttgcacc ttgtccaggc ccctcatgct gaactgacgc aatcccatca ccgccttgat
     6121 ccaaccattc ggagcctcca cgatcgactt gcgccggcgg taagctgcat cgccttgctc
     6181 cgttttcaat ttcgccgcaa tcgccgccgt atgcggatgg gtcttggcat tgaccttggc
     6241 atcttcacgt ccctcgcggc cgagggcaac gatgacatcg ccgtggtgat cggcgacctt
     6301 tgccagaaca gcctcactac ggaatcccgc atccgccagc gtctgggccg gcatttctcc
     6361 ggtgttggcc tgaactgctg ccagcatgcc cagcagcgcc tgactgtccg cggcgcagtt
     6421 ggtcaactcc gccgccacga tgatctggtg ctcggcatcg accgctgtgt acccgttgta
     6481 gctctgctcg gagccaccac cggcgtgttt catgatccgg ctgtccggat cggtgaagct
     6541 ttcctgatca cggtcatccg gcacaccaaa ctcgcgtttg tacgagccac cgcccttgtc
     6601 cgagccatcc ggatggcgag gccggcggcc atcgtcttcg ctgcgccccc gggcctggtc
     6661 cgcttcacgc tggcgcgctt ccaggcgcgc ctttgccgcc tggatcgcct ccaggcgctt
     6721 ctcgcggcga gaaatctcgg caggaatgtc cagctccggc tcgttacgct cctggtcgtc
     6781 ggtagccttg gcgcgatcaa gcagcgcctt gatctcgcaa tgcaattcgt cctcggccgg
     6841 cttcatgcgc ttatagctca tcgccttgtg gtcgccatgt ttggcggctt cgtattcagg
     6901 ttctttagag agatccttta gatcgccgtt cctcactact gccgggaagt ctccccaggg
     6961 agcacgttcg gccttatgtt cggtcatggt ttcaatcccg gtcagcgtcc catatagccc
     7021 cgaaacctgc caggtgggcc aagatagacc aggcaccata agcaataggg ctagggttgg
     7081 ttttgctcac ccaacgcctg aaggttcggg ttccctttcc gctgcctctc tcaccaggca
     7141 aaccaacgag atcagcgaca tcaacgccac tgagaggctt actaagccct tttcgttgcc
     7201 taatcagctc caacacctct ttgatttcat cggcggttgg agcctgccaa tcttcagcga
     7261 acggcctaag cgtttcaggt ctaatcatgc gataaatcct caaatagccc cggtcaatgc
     7321 cggggctttt ttatcaatgg gtaacggtcg cggcggcctc ccgatacgcc ttcagttcaa
     7381 tcaagagcaa gccaagctcc cgcatcttca tgcgcggcat atgaacgggg cggcgggccg
     7441 tcagagcgtc gccaatgtgt tttgcaagtg atacaatatc cgtattcatc gcgtttatcc
     7501 tcaaattgac cggtgaaagc ccctgtgatt ggttgcagcc ataccagggg caccatttct
     7561 ttttctacct atgcacctcc tttaagagcc ccggccatca ccggggcttt ctgttgctag
     7621 tctattgcgg ccaagatggc ctctttttcg tcatgctcac aagcccaatc ccgcaagctg
     7681 tgatacagcc ttgaaaaccg ctcctggtca gcgccttctg tgtgaaatga cagatggcta
     7741 tagaggtaga ggcaagcggt aatcccggca gcatcggcgc tcatttggcc actaaagtag
     7801 ttcatggcct cgatgttcag catttcatca cgacgcccag gagccatata aaagccgccg
     7861 ttcgacagct cccacataag ccaataagcc ccgcgatact cgcggcagag ccctttcatt
     7921 tgctggtaaa gcatcgactc gaaaaccaca tagaaacggc ctacatagcg gggcattgca
     7981 gccatacggc gaggggtggc gaccagggag cagatcaggg gattaagttc tgtttgcatc
     8041 atcggagttc tccggtattg accgtggcgg gtgcccggcc ttctgagata tataataggc
     8101 cattttggcc tattgtgtca agcgggtaca ataaaaaata ggccaaatcg gcctactttt
     8161 tttctctcca actgagccac attttattca gctccaggct gcgggctggc caatctggca
     8221 gattcaccgc atgggcgcgg tagttgatcc gagtattcag agtgcaacgg ggaaaggggt
     8281 tggccacctt gcagtaacga taaaacagac cgacgaggcg agcaccgtaa cgatcacgct
     8341 cccaggtcaa aacgttgtgc atatgctcgc ggcgttcgcg tatccattct cgatagagtt
     8401 ggtgaaaggt gcggttagct gtgtggatca tcggagttct ccggtattga ccgtggcggg
     8461 tgcccggtct tcttaattaa gattataggc caaaatggcc tactatggca agaaaaagcg
     8521 cgctctacgt taaaaaaatc acgtagtcgc gggggattgc cgccaagatt tcgcatagcg
     8581 tcgcctgatt tcgtacgtac gaaatgggcc acctggtcga gctgctgccg atgcctggtg
     8641 agttggccac ctggttgatt tccttctggc gtccagatct gaacttggcc acctggtcga
     8701 gctgctgccg gtgcctggta agttggccac ctggttgatt tccttctggc gtccagatct
     8761 gaacttggcc acccggtcga gctgctgccg gtgcctggta agttggccac ctggtcgaac
     8821 tgctgccgga tctaaaggtg gaatattaag caggtagtga tagactgaga tccagcatgg
     8881 ctatacgcct gctaacccct caaaagaaag cagcctctag ggctgccatc cgttacgaaa
     8941 tctcactcac tttgaaatag ccatctaaac ggctttacac ctggccgcct gaagggcaac
     9001 cgctgaggct tcgccattag taatagggga gggacttgtc tcactgtttt gttgaggtga
     9061 aggcttgccc aggcgatacc atttagcccg gctcatgccc atagcttccc agggcttttg
     9121 cctgctcaat gagttggctt cataggcttc acgctcaagc tggccagcgg cgcggcgacg
     9181 ttcttcatca cgcagtctat cgcgctctct gcggcgcttc tgagcctcgt cagtgctgat
     9241 aatcgtcttc agttgctctt gttcttgctg tgagatctgg aataggttga tcagcgtgtc
     9301 gtttttgggc gtgtatagcg gtgcaaacga ctttccgccg aactcgacac gttccccagc
     9361 ctcataggat ttcgccttgc tgtagagcgt cataagctct ttggagcggt aagaccaacg
     9421 agtatccagc tcggaggaaa gagcggcggc ctcatggtac atctgggcgc tgtttgttgc
     9481 cccggagaga aggagaaagt taagacgcca gaaaagatgc ctcattcgct cgccttcgtt
     9541 gattccacct ctgagctggc ccaacttgcg taggtcttcc agggggaacc gcagaattcg
     9601 gaaaaaatcg tacgctaagc taaggaaggt ctgaaaaagc ccccgctcga gaaatgcatc
     9661 ccagcaacca tgcgggttac agagcggtga tttcgcgaaa catgggcttt ttcagagctt
     9721 ccttagcgtt acgataaagc tagcatggaa acgataggtg caagcaagtt aagggttgca
     9781 tcgcgcatgt caatctaggc tataccctaa cttgatgtca ggcagggccg cgccgcttcg
     9841 tcagaataga gtctgctttc ccattttttg acacatgccc gcgaaggtta tagatttcag
     9901 cctgacagaa atgggctttg aggcacaacg gaacagaaag tgcacttaag ccgccttcaa
     9961 ccaaggagac atcgtgcagg ggcaccgcat cggctacgtc cgggtcagca gctttgacca
    10021 gaacccggaa cgccagctgg aacaaaccca ggtgagcaag gtgttcaccg acaaggcatc
    10081 gggcaaggac acccagcgcc cccagctcga agcgctgctg agcttcgtcc gcgaaggcga
    10141 tacagtggtg gtgcacagca tggatcggct ggcccgcaac ctcgatgacc tgcgtcgctt
    10201 ggtacagaag ctgactcagc gcggcgtgcg catcgagttc ctgaaggagg gcctggtgtt
    10261 cactggcgag gactcgccga tggccaacct gatgctgtcg gtgatggggg ccttcgctga
    10321 gttcgagcgc gccctgatcc gcgagcggca gcgtgagggc atcgccttgg ccaagcagcg
    10381 tggcgcgtac cggggccgca agaaagccct gtccgatgag caggctgcta ccctgcggca
    10441 gcgagcgacg gccggcgagc ccaaggcgca gcttgcccgc gagttcaaca tcagccggga
    10501 aaccctctac cagtacctcc gcacggacga ctgacacatg ccgcgtcgct tgatcctctc
    10561 ggccacggag cgggacaccc tgcttgcgct gccggaaagc caggatgacc tgatccgcta
    10621 ctacaccttc aacgactccg acctgtcgct gatccgccag cgacgcggcg acgccaaccg
    10681 cctcggcttc gccgtgcagc tctgcctgct gcgctacccc ggttacgcgc tgggaaccga
    10741 cagcgagctg cccgagccgg tcatcctgtg ggtggcgaag caagtccagg ccgagccggc
    10801 gagcgcgacg tgacccgtcg cgagcatgcc caggaactgc gcacctacct gcaactggcc
    10861 ccgttcggcc tgtccgactt ccgcgccctg gtgcgcgagc taaccgagct ggcccagcag
    10921 accgacaaag gcttgctgct ggccggtcag gccctggaga gcctacggca gaaacgacgc
    10981 atcctgccgg cgctgagcgt gattgaccgg gcctgctcgg aagccattgc gcgagccaat
    11041 cggcgggtct accgcgccct ggtcgaacca ctcacggact cgcatcgggc caagctggac
    11101 gagctgttga agctcaaggc cggcagcagc atcacctggt tgacctggct gcgccaggca
    11161 ccgctgaaac ccaactctcg gcacatgctg gaacacatcg agcggctgaa gacatttcag
    11221 ttggtggact tgcccgaagg cctgggccgg cacatccacc agaaccgcct gctcaagctg
    11281 gcccgcgagg gtgggcagat gacgcccaaa gacctcggta agttcgagcc gcagcgccgc
    11341 tacgcgaccc tggccgccgt ggtgctggag agcaccgcga ccgtgatcga tgagctggtc
    11401 gatctgcatg accgcatcct ggtcaagctg ttcagcggcg cgaagcacaa gcatcagcag
    11461 cagttccaga agcagggcaa ggcgatcaac gacaaggtgc gcctgtactc caggatcggc
    11521 caggcgctgc tggaagcgaa ggaaagcggc agcgacccct atgccgccat cgaggcggtg
    11581 attccctggg acgagttcac cgagagcgtc agcgaggccg agctgctggc ccggccggaa
    11641 ggcttcgacc acctgcacct ggtcggcgag aacttcgcca ccctgcgccg ttacacgccg
    11701 gccttgctgg aggtgctgga actgcgcgcc gcgccggccg cgcaaggcgt gctggcagcc
    11761 gtgcagaccc tgcgtgagat gaacgccgac aacctgcgca aggtgccggc cgatgcaccc
    11821 acggccttca tcaagccgcg ctggaagccg ctggtgatca ccccggaagg cctcgaccgg
    11881 aaattctacg aaatctgcgc cctgtccgag ctgaagaacg ccctgcgctc cggcgacatc
    11941 tgggtcaagg gctcgcggca gttccgcgac ttcgacgact acctgctgcc ggccgagaag
    12001 ttcgccgcac tcaagcgcga gcaggccctg cccctggcga tcaacccgaa cagcgaccag
    12061 tacctggaag agcgtttgca gctgctggac gagcagttgg ccaccgtcac ccgcctggcc
    12121 aaggacaacg agctgcccga tgccatcctc accgagtcag ggctgaaaat caccccgctg
    12181 gatgcggcgg tgccggatcg ggcgcaggcg ctgatcgacc aaaccagcca gttactgccg
    12241 cgcatcaaga tcaccgaact gctgatggac gtggacgact ggacgggctt cagccgccac
    12301 ttcacccact tgaaggacgg ggccgaggcc aaagacagga cgttgctgct gtccgcaatc
    12361 ctcggtgatg cgatcaacct cgggctgacc aagatggccg agtcgagccc cggcctgacc
    12421 tacgccaagc tgtcctggct gcaagcctgg cacatccgcg acgaaaccta ttcggcggcc
    12481 ttggccgagc tggtcaacca ccagtatcgc cacgcctttg ccgcccactg gggcgacggc
    12541 acgacctcat cctccgatgg ccagcgcttc cgcgcgggtg gccggggcga gagcaccggg
    12601 cacgtcaacc cgaagtacgg tagcgagccg ggacggctgt tctataccca tatctccgac
    12661 cagtacgcgc cgttcagcac ccgcgtggtg aatgtcggcg tccgcgattc cacctatgtg
    12721 ctcgacggcc tgctgtacca cgagtccgac ctgcggatcg aggagcacta caccgacacg
    12781 gccggcttca ccgatcacgt ctttgccctg atgcacctgc taggcttccg cttcgcgccg
    12841 cgcatccgcg acctcggcga aaccaagctg tacgtgccgc agggcgtgca agcctacccg
    12901 acgttgcgcc cgctgatcgg cggcaccctg aacatcaagc acgtgcgtgc ccactgggac
    12961 gacatcctgc gcctggccag ctcgatcaag cagggcaccg tcaccgcctc gctgatgctg
    13021 cgcaagctcg gcagctaccc gcgccagaac ggactggccg tggccctgcg cgagctgggc
    13081 cggatcgagc gcacgctgtt catcctggac tggctgcaaa gtgttgaact gcgccgccgc
    13141 gtgcatgccg gcctgaacaa aggtgaggcg cgcaactcgc tggccagggc ggtgttcttc
    13201 aaccgccttg gggaaatcag ggatcggagc ttcgagcagc agcgctaccg ggccagcggc
    13261 ctcaacctgg tgacggcggc tatcgtgctg tggaacacgg tgtacctgga acgcgccacc
    13321 caggggttgg tcgaggccgg caagccggtg gacggcgagc tgctgcaatt cctgtcgccg
    13381 ctgggctggg agcacatcaa cctaaccggc gattacgtct ggcggcagag ccgcagactg
    13441 gaagacggga agtttcggcc cttacggatg cccggaaaac cttagcgtac gattttttcc
    13501 gaattctgcg ggctcccctt aatgaccagc acagtcgtga tggcaaggtc agaatagcgc
    13561 tgaggtctgc ctcgtgaaga aggtgttgct gactcatacc aggcctgaat agcttcatca
    13621 tccagccaga aagttatgga gccacggttg atgagggctt tattgtaggt gggccagttg
    13681 gttattttga acttttgctt tgccacggaa cggtctgcgt tgtcgggaag atgcgtgatc
    13741 tgatccttca actcagcaaa agttcgattt attcaacaaa gcccattcag tcctcaattt
    13801 gtgcattttt taaacgaaaa aagggtgtct aatacggtga aatcatagta ttaccaaagt
    13861 aataaataaa aagttattta aatcagtaat ttagatttga tttgtaatac ctgggtaata
    13921 ccgcagcatg gctaaatttt gttttttttc ttttaaatca gtgcgatagc gtgatttatc
    13981 acgctgcgtt aggtgtatag caggttaagg gataaaaaat catctttttt ggtaggggcg
    14041 atctacgtag gttaaggact aactggctaa aaagcgttca atattccgta ttcatgcttg
    14101 catgaatacc agtacaacaa aagtacatca aaattacatc aaaattacat cacttgaagg
    14161 ttgacagtac aacaaaatta catcattctt tggtcatgag gtagccagta caacaaaagt
    14221 acatcaaaag tacatcaaaa ttacatcaaa attacatcat tctaaatgag ggtactatga
    14281 agcccaaaag tatcagggcg gcacttcagt tgatgttgcc ggaaatagaa gaaatgctgt
    14341 cactgggagt ttccagggag gaaatttata aggcagtttc tgaacgcttc ggcctggaag
    14401 gtgtgaacgt tcgtagcttt gatacgtccc tatatagagc gcggcaaatc cggaaaaatg
    14461 gaatgcacaa tacacatgaa aggatgccga acaatgatga tagtgtattg cacaatacac
    14521 aaacgccgcc tgagcctgaa ccgcaaggaa gtgaaaaaaa agaaagtccc ggcattattg
    14581 ataaagagtt cttcaataaa atcagtgaag atttcgaccc taagatgttc aataaaaaat
    14641 tctgaggtga tttatgaaag tagcggtaat taattacagt ggcagcgttg gtaaaacctt
    14701 aatttcatcc tacctgttag ccccgcgtct gactggagca aaattctatg cggttgaaac
    14761 tatcaaccag tctgcttccg atctggggat tgagaatgtt tccattttta aaggtgatga
    14821 cttttcacgg ttgattgaag atattgtttt tgaagatgcc gggattattg atattggtgc
    14881 gtcaaacgta gaagcgttcc tgatggcaat gtcccgcttt gacagtggcg cgaatgaatt
    14941 tgataagtat gtaatcccgg ttacgcctga taataaggcc attgatgaaa gcctgaaaac
    15001 agcacatacg ttaagtaagg caggtgtaag cagcgataaa atcatctttg ttccaaaccg
    15061 cattagtcca gatagtgaag tagaggatgt actggcgccg gtatttgaat ttgtcaaacg
    15121 aacgaaagtt ggcaaaatca gcaagaaatc tgttatttat aacagtgaag ttttcgaata
    15181 tctcgcgtat caccgtatct cattcgaagc attgaccgct gaagatccag aagaatttaa
    15241 agcccgcgct aaacaaacaa cggatgctga cgagcgcaaa aaactggccc gccgttatac
    15301 ctacatgaaa caggcaattc ctgttaaagc taatctcgat aaagcatatg cggctttaat
    15361 gggagaataa aatggaaaag cagccagata aatttgaagt tctgatggat tggtttttag
    15421 gtgacgcgaa ggaaatcacc gcaagtcaga aagaaatgac tgagatactt tctgcgcttt
    15481 cggaaaagct ggcaaaagac accgaaagtt taggagagac ggcagactct cttaaacgga
    15541 ctttagtaga aaaccagcgt tcaattagcc tggcaattag tgatgatgct aaggcgcgtg
    15601 aggaatttct gacgaagttc cgccgcgcgc aggcgtccag agctgagacg ttaacccgtc
    15661 agatcctttt tattacagct ggctgcacta ttgtgggcgc cgccgtgggt gccgcgatag
    15721 ccataattct actgagataa tgtaaaccgg gcatgtcccg gttttttttc aagcgaagcg
    15781 cggaggccgc aggccggagg cattagtggc cgccgcccga aggggcgaga cgcgtagcgg
    15841 ctcgatgcgc agcacggcag aacggccccg caggggtaat gcccggttta attcaacgtg
    15901 acagtcacgt ggaggaaaaa tatgaatgac cgacagcgtg aacaagcccg tattcgccag
    15961 gcccggcgcc gcgcgcgact caaagaggaa ggcgctagcg tgacagtcac gctaacaaaa
    16021 caggaagaag caatgttaca ggagctttgc cgggttcgtc gtccaggacg aacagcctat
    16081 tccacgaatg agtttttcca actgctgctg atccgaaact ggcaacagtg gcaggagcaa
    16141 aaggcgcagc tggggaaatg ccaggcttgc ggaaagctga aagcggaggg aggttgcggc
    16201 ggcgaacggc agagcgaaac ctttaactgc tggctagccg tcgaagcaaa cgagcttaat
    16261 gtgtagtgta ttgtgctata cagaaattgc caaaagcagc gcggagtaat aactgaaacg
    16321 gccgcgcagc ggaaagaaaa aagcccggtc aatccgggtt tttttctttc ggcggctcag
    16381 taatcgtcta gatctccgca gcccagcggg caacaattac gctcaatacc gtggctgcaa
    16441 taatcgtttt cccgatcctg ccggatttct tccgcgatct cgtcttgggt cagatagtca
    16501 aattcacgcc gcgctaccgc gatcagttct tcccgatact cggccggaac gccagcaaga
    16561 tagccgtcaa taaccgcgct caggcggcgc tgatacagtt cataaatcag gccgcagcgg
    16621 ggctgctgtt cgcgcgcaaa actctcacac tggcgacgaa aatcttcaag agtctgctca
    16681 agggtttgtg tggtcatgtc gtttgtcctc gatctttctg ttaaagaccc ggcttggccg
    16741 ggtcgtcagt gctatttagt ttgttgcagc agctggtcta attttgccgc cagtgcatac
    16801 gtcgatgtga aagcgccttg caggcgctga ttaggcagct ggttgaacgc ttcgaggcag
    16861 gcgcgcagca ataattcttt ctgagattcg acttcttttt tcagctggga aggggtggta
    16921 acagtggtca tgcttactcc ttagtgatcc gataccggca atttttcggg tggcggtatt
    16981 gcctcccgat gatttaatta tcggtgatta cgcctttaaa gtcaatacaa gtacggaatt
    17041 tatttacatg tttttatgcc cgtcagggca tggaaggcga ccgcgccgga ctccaccgga
    17101 caccggccgc aaatcgccgg aaactgcggg actgaccgga gcaacaggcc aacccccctt
    17161 cctgctaagc cataacccag cccgccgcca cgcagctgcc gcacgtcccc cacgggggtg
    17221 cgcagtgggc gccgcgcgcc tgcgcgcggg tacagcggcc cgcctgcggg tcgcggcgcc
    17281 gtactgcgag ttagcggccg ccgcgcggcc ggttacgggg gacaccgcac cgtcacggcc
    17341 agcgccccgc tgagctgcac aatccacgga taacacaata gcgcactggc aaaggatgcc
    17401 gacgcctgaa gggcgttggc accccgaagg ggcggggcga gacgggaacc ggctcgatgc
    17461 gcagcacagc agagcggccc cgaaggggta acgccctgtg tggcatcagg atttagcgca
    17521 atggcagaac atgagctgga gagatcaccg gcaagcagca gcaaaggggc ggcgcagccg
    17581 cccagatggc tgtttgccga taccggcgat taattagagc ggtgtttaat atcccccgcg
    17641 tggcggggga ctaggtttca gcaagtcatg ttaaatacgt gtccgtcatg taaactgaaa
    17701 tccccaataa acagatcccg cgcataggct acgatgtcaa aatatcgggc tacggattca
    17761 ggaatttcat tcagtagacc gctatcattc aggtattcct ctgcaaaagt ttcttcgtcc
    17821 ttagcttcgc ccatataggc atctctaaac aggtcgaaat cagtgctatt aaacagatca
    17881 acaaaggcca caaacgccgc ttcgtttcct tcctcgcggg cttgtttaaa gccgttaata
    17941 aaatcccagt tgatatggca ctctgacgcc atatcagacg gaataccctc ccaatcctgg
    18001 aacataaatt ctggatcagc ctcatttgcg tgtaactcgc ggcagcgctc gtaaaactcc
    18061 tctgagctat caaaatcggt cagatcgagc caggctcccg caatgcttcc gcagttgtat
    18121 ttatggtaag tgccaacata aacagaaggg gtcgtaatat cagtcatggt gtactcctta
    18181 aagcgccgat accggcaatt tttcgggcgg cggtattgcc tcccgatgat ttaattatcg
    18241 gtgattacgc ctttaaagtc aatacaagta cggaatttat ttacatgttt ttatgcccgt
    18301 cagggcatgg aaggcgaccg cgccggactc caccggacac cggccgcaaa tcgccggaaa
    18361 ctgcgggact gaccggagca acaggccaac cccccttcct gctaagccat aacccagccc
    18421 gccgccacgc agctgccgca cgtcccccac gggggtgcgc agtgggcgcc gcgcgcctgc
    18481 gcgcgggtac ggcggcccgc ctgcgggtcg cggcgccgta ctgcgagtta gcggccgccg
    18541 cgcggccggt tacgggggac accgcaccgt cacggccagc gccccactga gctgcacaat
    18601 ccacggataa tgcaggagac gaatcatgat aggaggctga aggggaaatg agcggcagca
    18661 ggggaagggg ttgccaagcg gagcgcggag gccgcaggcc ggaggcgtca gtggcagctg
    18721 cccgcgtgag cggggcgaga cgcgtagcgg ctcgatgcgc agcacagcag aacggccccg
    18781 gaggggtgac gtccgggggt tcgcttttaa agattttcga ccacatcagt aaatcgtagt
    18841 gacaccatga agcaaaagta tcgtgcagac cagaatcaac aacagtaaca gcagaccttt
    18901 ttttcgacgt aataaaaccg gccccaaagc gcccgcaaga agcacactca acacgatttc
    18961 cgttatgcta atcgtattca taatctctca cgtttccctt tttagaactc tgccacacac
    19021 ggataaaacc ttataacaaa gcaacaaaac ccgttattca gacacggtaa tgcctagttt
    19081 ttttgccaga atttcagatg acaaagaaac ccttatcgac ttcccggtta caaggtgaat
    19141 gattgtggct tcatgccctt caacagagtg ggatattaac tcacgctgaa tgatatgcgt
    19201 ctctccatca tttcccgtca cggctattag gctctctgta gaacaggggt tgatactact
    19261 aatgttggtg ttgttttcgg ttttgttcag catcgctgat cctcaaatat cggtttgtgt
    19321 tacgtctgcc gctttgcgct ggataagcga cttaaagaaa tccgacgcct tcagaatatc
    19381 gctatcctgg aagtcgggaa atgtcgcttc tgtcagctcc tgcgccgtac ctgcccgtat
    19441 aacggtttca tcgcggatca tcgttcgctt aacgccatca gcctgttttt tgctgaagga
    19501 gtgccggaaa ataatcgcgt attggccgcc gctatcctga tgaacagaag tatcccagcg
    19561 atgattaccc tgtttacgat agtggtgata gatttgctgg ccgtagcgct cctgatcgga
    19621 attacggtaa tcgaacatta acagttccaa aagcattaac cgatctggca attgccaggc
    19681 ggtagggtgt tgaagtgtcg ctaacatagt ttcccctgag cgtgacagtc acgataaggc
    19741 gggctttgcc cgcctggtta tcagttaatc aatggcacga taaatacgat tctggctttc
    19801 gttctccagc gtattaacgt actcccgcaa caggtgatac cggttagcca tcgtttcgtt
    19861 cagttcggct ttgccttctt catatgccag cccgcaaaag taactgtagg catacagaca
    19921 aacaataatc cctacttcgc gcgcgctgca ttcaccttca aaatagttag gtaacgagag
    19981 ccaaagaggt tggggcgctt ccataaaaaa cgcgccattg ctggcctgaa ggtattccca
    20041 ataccctccc tggtagtctt tagcgtaacg attcagaaag gactgaatga agtgatctgc
    20101 gctgaagaaa gcgccacgaa atgccgcagg catgaagttc atgcgggcgt tttcagaaat
    20161 gtagcgggcg gtgatttcga tagtttccat gatacttcct ctttaagccg ataccggcga
    20221 tggttaagcg gcaggcacat cacctgccac tttttaatta tcgtacaatg gggcgttaaa
    20281 gtcaatacaa gtacggatta tatttaccta attttatgcc cgtcagagca tggaaggcga
    20341 cctcgccgga ctccaccgga caccgggggc aaatcgccgg aaactgcggg actgaccgga
    20401 gcgacaggcc acccccctcc ctgctagccc gccgccacgc ggccggttac aggggacact
    20461 gagaaagcag aaagccaaca aacactatat atagcgttcg ttggcagctg aagcagcact
    20521 acatatagta gagtacctgt aaaacttgcc aacctgacca taacagcgat actgtataag
    20581 taaacagtga tttggaagat cgctatgaag gtcgatattt ttgaaagctc cggcgccagc
    20641 cgggtacaca gcatcccttt ttatctgcaa agaatttctg cggggttccc cagcccggcc
    20701 cagggctatg aaaagcagga gttaaacctg catgagtatt gtgttcgtca cccttcagca
    20761 acttacttcc tgcgggtttc tggctcgtca atggaagatg gccgcatcca tgatggtgac
    20821 gtactggttg tggatcgctc gctgacggcc agccacggct caatcgtagt cgcctgcatc
    20881 cataatgaat ttaccgtgaa gcggctactg ctgaggccca gaccctgcct gatgccgatg
    20941 aacaaagatt ttcctgtgta ctacattgac ccggataatg agagcgttga aatctgggga
    21001 gtggttacgc attcccttat cgagcatccg gtatgtttgc gctgattgat gtcaatggca
    21061 tgtacgccag ctgtgagcag gcatttaggc cagatctggc aaaccgagca gtggccgttt
    21121 tatccaacaa tgacggcaac attgtggccc gtaattacct ggcgaagaaa gcgggcctga
    21181 aaatgggcga tccgtacttc aaagtcagac ccataatcga gcgtcataac atcgctattt
    21241 ttagctctaa ttacactctc tatgcctcca tgtcggcccg gttcgcggcc gtagttgagt
    21301 cccttgcaag ccacgtcgaa cagtattcaa tcgacgagct ttttgttgac tgcaaaggga
    21361 taacggccgc catgagcctt gacgctttcg ggcgccaact gcgcgaggaa gtcaggcgac
    21421 acacaacgct ggtatgcggg gtcggtattg cccgtactaa gacgctggcg aagctgtgta
    21481 accacgctgc aaaaacatgg cccgctactg gcggggtggt tgctctggac gatggcgcca
    21541 gactgaagaa attaatgagc atcctgccgg ttgcggaagt ctggggcgtc ggccatcgta
    21601 cagagaaagc actcgccaca atggggatca aaacggtgct ggatttagcc agggcagata
    21661 cgcgcctaat ccgtaagacg tttggtgttg tgcttgaaag aacggtacgg gagctacgcg
    21721 gcgaggcttg cttcagcctg gaagaaaacc ctccggcgaa gcagcagatt gttgtatcgc
    21781 gctcattcgg ccaacgcgta gtagccctgg cggatatgca gcaggcgatc accggatttg
    21841 cagcgcgcgc agctgaaaaa ctgcgtaatg agcggcaata ctgccgcgtc ataagcgtct
    21901 ttatccgcac cagtccttat tcagtgcgtg atacacagta tgccaatcag gcaaccgaaa
    21961 aactgacggt ggcaacccag gacagccgca cgataattca ggcggcacaa gccgcgctgg
    22021 cgcggatctg gcgggaagat attgcgggca ctgttgcaaa gttagcgatg aggcagcctt
    22081 ttgtcttatt caaaggcctt acatttcaaa aactctgctt accaggcgca tttcgcccag
    22141 gggatcacca taataaaatg ctgaggcctg gcctttgcgt agtgcacgca tcacctcaat
    22201 acctttgatg gtggcgtaag ccgtcttcat ggatttaaat cccagcgtgg cgccgattat
    22261 ccgtttcagt ttgccatgat cgcattcaat cacgttgttc cggtacttaa tctgtcggtg
    22321 ttcaacgtca gacgggcacc ggccttcgcg tttgagcaga gcaagcgcgc gaccataggc
    22381 gggcgcttta tccgtgttga tgaatcgcgg gatctgccac ttcttcacgt tgttgaggat
    22441 tttacccaga aaccggtatg cagctttgct gttacgacgg gaggagagat aaaaatcgac
    22501 agtgcggccc cggctgtcga cggcccggta cagatacgcc cagcggccat tgaccttcac
    22561 gtaggtttca tccatgtgcc acgggcaaag atcggaaggg ttacgccagt accagcgcag
    22621 ccgtttttcc atttcaggcg cataacgctg aacccagcgg taaatcgtgg agtgatcgac
    22681 attcactccg cgttcagcca gcatctcctg cagctcacgg taactgatgc cgtatttgca
    22741 gtaccagcgt acggcccaca gaatgatgtc acgctgaaaa tgccggcctt tgaatgggtt
    22801 catgtgcagc tccatcagca aaaggggatg ataagtttat caccaccgac tatttgcaac
    22861 agtgccatat tgcgtatgca aaagcaggga tcatgctggc cgatttcagc ggaaaggagg
    22921 cccagctgga tttattcgac tctgctacgc cttcagctgg cagcgaggcg ttaatggctg
    22981 ttctcgatgg cataaaccgg cgtggcaaga gccagctgtt ttttgcaggc cagggcatcg
    23041 ataactcctt tgccatgcgc cgtcagatgt tgtcacctga ttacacgaca gactggcgct
    23101 cgataccaac agcaaccatc aaataattac cggcgccgca cgcgggccgg tcaacccctc
    23161 aaccggccga aacgagtttc ggcgcggttt cgcggttttc ggtaaaaggc gtttcatctg
    23221 tataaaagat cagctaaatt atgtgtattg cacaatacat atatgtgagg ttaacagtga
    23281 atttgcctac gcccgaaacc tacgatgaac ttcagagagc ctacgatttt tttaatgaga
    23341 agctattcag caacgagctg ccgccatgcc tgataacgtt gcagcgtgag aagcgaacgt
    23401 atggctattg ttcctttaag cgtttcgtcg gccgtgagag tgggtacacg gtagacgaga
    23461 tcgctatgaa tccggtgtat ttctcgatca gaaccataaa ggccacgctt tcaacactgg
    23521 tgcatgagat ggttcatcag tggcaattcc attttggcga gcctggccgc cgtggctatc
    23581 acaacaaaca gtgggcggcc cggatggaac gggtaggact aatgccttct gataccggcg
    23641 aaccgggagg caggaaagtg ggccagagca tgacccatta tattattgcc ggtggccctt
    23701 tcgatatggc ctgtgatgaa ctgctgacag gccatttccg gctttcctgg atggacaggt
    23761 ttccgcctta ccagcctaag cctggcgctg tgctaagccc tacaggaaaa ggctatattg
    23821 acgacgagga agatgatagc gaacacgaac aggaggtgga ggaagggcgc gacccggttg
    23881 aactcgacga cgagatcata gaggccatgc gatttgtaac cccgccgcct gaagcgccgg
    23941 tgaacaaaac aaaccgggaa aagtacagct gcccggtgtg tcatatcaat ctctggggta
    24001 aaccggggat agtggtttac tgtggtggcg agcactgtaa taaagccgcg ttagtagtct
    24061 taaaataaag tcctttcgga ctttattttt tttccatttc cgaggtcgtg atgttattaa
    24121 tgctgtactt cgcggcttct tttaaaacag tttcagcaag gcttgctggt atccagacct
    24181 gaactaattt taatggttcg ccgttctcgg ctttaagagt ggtgttctgg tacaaatccc
    24241 agattcgctt aacggtgctg gaaatgtttt gcttggaacg gcctactcgc gtggctacgt
    24301 ctgatgattt ctcacctttg acaagcacgg aatagccaat atctgttgtg atgtgtgcaa
    24361 aggaagccat ttgcggcagc agctgtttcc attctgtttc tgaaattctg tttttctgag
    24421 ccatctgtgg cgcctccgta gttttggtta cagaaaggat atactcagaa taaactgggg
    24481 tcaatacaag tacgattttt ataaacttta ttttatttga gggtgaggcc cggtgcggca
    24541 gcagcgcggg cctcgatggt gccgcgaagg tgctggcgcc atgcttggat taaaacatga
    24601 accgtgaaga actgcgaaac ttgttttcgc ggttctgagg ggttgaccga gccgcgaagc
    24661 ggcgctggta agcgatgata tgcacatatc cacaggcata tttttaaaag gtattttata
    24721 gattttttat ctttttaaag tcttttagag ctatataact cattgattta aaatcataaa
    24781 taagtgttat ctctgggaat ccgcccacct tgttatggga attggcccac ctatctatgg
    24841 gaaacacccc accttactat gggaattagc ccaccttgtt atgggaattg gcccacctta
    24901 gacgaaactg taaaaaatgt atttacttgt ttgaactttg tggtagtgtg gagagtaatt
    24961 tttaacccac aaaggcaagg ctc
//
