LOCUS       NZ_CP044202            10046 bp    DNA     circular CON 10-NOV-2023
DEFINITION  Salmonella enterica subsp. enterica serovar Corvallis strain AR-0406
            plasmid pAR-0406-2, complete sequence.
ACCESSION   NZ_CP044202
VERSION     NZ_CP044202.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN12648956
            Assembly: GCF_008727555.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Corvallis
  ORGANISM  Salmonella enterica subsp. enterica serovar Corvallis
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10046)
  AUTHORS   Chen,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2019) EDLB, Centers for Disease Control and
            Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 59.02x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/10/2023 04:55:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,677
            CDSs (total)                      :: 4,553
            Genes (coding)                    :: 4,404
            CDSs (with protein)               :: 4,404
            Genes (RNA)                       :: 124
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 17
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 76 of 149
            Pseudo Genes (incomplete)         :: 87 of 149
            Pseudo Genes (internal stop)      :: 28 of 149
            Pseudo Genes (multiple problems)  :: 35 of 149
            Pseudo Genes (short protein)      :: 1 of 149
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP044202.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..10046
                     /organism="Salmonella enterica subsp. enterica serovar
                     Corvallis"
                     /mol_type="genomic DNA"
                     /strain="AR-0406"
                     /serovar="Corvallis"
                     /sub_species="enterica"
                     /db_xref="taxon:593905"
                     /plasmid="pAR-0406-2"
     gene            complement(join(<9452..10046,1..436))
                     /locus_tag="F4V18_RS23475"
                     /pseudo=""
     CDS             complement(join(<9452..10046,1..436))
                     /locus_tag="F4V18_RS23475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612174.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            831..1487
                     /locus_tag="F4V18_RS23480"
     CDS             831..1487
                     /locus_tag="F4V18_RS23480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrS1"
                     /protein_id="WP_001516695.1"
                     /translation="METYNHTYRHHNFSHKDLSDLTFTACTFIRSDFRRANLRDTTFVN
                     CKFIEQGDIEGCHFDVADLRDASFQQCQLAMANFSNANCYGIEFRACDLKGANFSRTNF
                     AHQVSNRMYFCSAFISGCNLSYANMERVCLEKCELFENRWIGTNLAGASLKESDLSRGV
                     FSEDVWGQFSLQGANLCHAELDGLDPRKVDTSGIKIAAWQQELILEALGIVVYPD"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrS1"
     gene            complement(1806..2420)
                     /locus_tag="F4V18_RS23485"
     CDS             complement(1806..2420)
                     /locus_tag="F4V18_RS23485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017412822.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_014839983.1"
                     /translation="MFIGYIRMSKADGSQTNDLQRDALIAAGVDAAHFYEDRASGKREE
                     RPGLTACLKALRPGDTLVVWKLDRLGRDLRHLINTVHDLTARGTGLKVLTGHGATIDTT
                     TAAGKLVFGIFAALAEFERELIAERTTAGLASARARGRNGGRPYKMTPVKLRLAMASMG
                     QSETKVSTLCQELGITRQTLYRHISPVGQLRADGIKLFNRG"
                     /name="recombinase family protein"
     gene            2582..>2764
                     /locus_tag="F4V18_RS23490"
                     /pseudo=""
     CDS             2582..>2764
                     /locus_tag="F4V18_RS23490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060658.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /name="DUF4158 domain-containing protein"
     gene            2900..3445
                     /locus_tag="F4V18_RS23495"
     CDS             2900..3445
                     /locus_tag="F4V18_RS23495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid pRiA4b ORF-3 family protein"
                     /protein_id="WP_001493763.1"
                     /translation="MVWRRLRIAADTSLAALHFIFQIVQGWGDDHLHQFHIYGKDYGIS
                     YEGGIGFVDNPFRVVIDDFAFDAGDRFTYEYNFFEHWLHDIRVEAIYENSTLKAPFCIS
                     GHGMPGATAADEFDKTLAFLEAIVNADDETTVGEIRPFADDLDAVRFNRHKINRQLSRL
                     DLASPVLEPEVIWLGRRR"
                     /name="plasmid pRiA4b ORF-3 family protein"
     gene            3582..4154
                     /locus_tag="F4V18_RS23500"
     CDS             3582..4154
                     /locus_tag="F4V18_RS23500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493762.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001493762.1"
                     /translation="MQYAYIRVSSADQNTARQEEALSKAGFQPDKICVEHASAKDTNRP
                     GLQELLGQLRPGDTLLVHSIDRLCRNMSDMCAVTTRLRDQGVTLIFLKEQLTFSAGTNN
                     PMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEKTGRPGADIKKIQEIDALRSRG
                     VRLRIACDHAGLGVSTYYKLRHQMNNQ"
                     /name="recombinase family protein"
     gene            4191..>4796
                     /locus_tag="F4V18_RS23505"
                     /pseudo=""
     CDS             4191..>4796
                     /locus_tag="F4V18_RS23505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493761.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ISKra4-like element ISKpn19 family transposase"
                     /name="ISKra4-like element ISKpn19 family transposase"
     gene            complement(4724..6100)
                     /locus_tag="F4V18_RS23510"
     CDS             complement(4724..6100)
                     /locus_tag="F4V18_RS23510"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017900944.1"
                     /GO_function="GO:0009975 - cyclase activity [Evidence IEA]"
                     /GO_process="GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="WP_080196049.1"
                     /translation="MVNVEFFNYIECIFMRIKKPHLRPIVITLSVGGILLTSIFLIVVI
                     MVFKRENIEKDLLDANSSYAMKMSDVMSNYIEIAQRELAYGAKKIESTNDIDSLKNEAD
                     RLRLQSGMFNSVLVVSDGAVVLATSPESLGLVGVHLNSSASKLAIEAKKPFISAPYKSA
                     SGNLIIFLSHPIYDKNSNYIGYVGGSIYLKEQSLFSDVLSRHFFKSDTEISIVSDDGNV
                     IFNNDNSAVGRPMVMDDNLKSKLTSSERGEGIFFSSGNKYLLGYAHMKNTAWSVLVYSH
                     ADSVTTILITYAKSVLVLLIVIVITFSLFSYFIASRISIPLEKLAISTNAKDIGGSLVD
                     IKGINAWYVEADRLKKALFTHIKIMIERVDSLNEVALKDPLTGVNNRLGFSNKIQNHKQ
                     GSGASVIAIDVDFFKKINDNFGHGVGDEVLVTLAQVINCGFPGLGRFPQSRGQPERKPE
                     "
                     /name="diguanylate cyclase"
     gene            complement(6405..6620)
                     /locus_tag="F4V18_RS23515"
     CDS             complement(6405..6620)
                     /locus_tag="F4V18_RS23515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_000137421.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWENAFAEWRTMSGLMQRENA
                     ALSERVTGLSRQVQSLSEQLRRLSQG"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(6624..7109)
                     /locus_tag="F4V18_RS23520"
     CDS             complement(6624..7109)
                     /locus_tag="F4V18_RS23520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012565228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_012482081.1"
                     /translation="MSSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEQSVRAELNESE
                     KRISAAILDHDRKLSSAMSQRTKGMVRMVSQTWLTIVLVSVLLIASSAGILWWQSQQIL
                     DNYTTIREQKSTQAMLSERNSGVQLSTCGEQRRSCVRVNPEAGRFGEDSSWMILAGK"
                     /name="MbeB family mobilization protein"
     gene            complement(<7144..7848)
                     /locus_tag="F4V18_RS24090"
                     /pseudo=""
     CDS             complement(<7144..7848)
                     /locus_tag="F4V18_RS24090"
                     /inference="COORDINATES: protein motif:HMM:NF015397.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(7787..8110)
                     /locus_tag="F4V18_RS23530"
     CDS             complement(7787..8110)
                     /locus_tag="F4V18_RS23530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_015059464.1"
                     /translation="MLTIWVTEDEHRRLLDRCDGKQLAAWMRQTCLDEKPARAAKLPSI
                     SPALLRQLAGMGNNLNQIARQVNAGGGTGHDRVQIVAALMAIDAGLERLRHAVLEKGAD
                     DDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            8760..8918
                     /locus_tag="F4V18_RS23540"
     CDS             8760..8918
                     /locus_tag="F4V18_RS23540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001658417.1"
                     /translation="MHEPPVQSDCCASSGNFQLDSNPERHDKAPLAAAIGNWELVDLDI
                     ESLEVVA"
                     /name="hypothetical protein"
     gene            complement(9161..9466)
                     /locus_tag="F4V18_RS23665"
     CDS             complement(9161..9466)
                     /locus_tag="F4V18_RS23665"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA];
                     GO:0046872 - metal ion binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_223229636.1"
                     /translation="MPKPDNSCCRSEDIVCRFGGEEFVVFLPNTSVVTAECVAERIRSV
                     IESTVFPNNLRVTVSAGVATQEDPLGGIDFLLKNADDALYQAKGEGRNKVIVYSAI"
                     /name="GGDEF domain-containing protein"
     ARG             832..1484
                     /name="qnrS1"
                     /gene="qnrS1"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrS1"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          8381..8927
                     /name="rep_cluster_2335"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="91.652"
                     /coverage="90.0"
                     /evalue="0.0"
     Typing          complement(6302..7797)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="91.583"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tcagatggcc ggtgaacccg aatgctcaac tgcgcacgcg acacgccaag acttctgcaa
       61 acgtcgctta ttcgtcgttc ccaggcaacg agggcgcatg cgcaatccat ttttttgccc
      121 ggccgaactc cacggcctct ttgagtatct cggcttccat cgtctttttg cccagaaggc
      181 gctggagttc gcgaatttgc ttattggcgg cagcgagttc ggaggccggc accacttcct
      241 cgcccgatgc aacagccgtc agtgaaccgt cttaatattg cttgcgccat ttgaatatct
      301 ggtttgcatt gatgccatgc aggcgcgcga catgagacac ggtcataccg ggctccatag
      361 tctgctgaat aatggcaatt ttttcctgcg gtgtacgacg ccgacgccgc tcaggtcctg
      421 ataacacttc aaccatctta tcgttctgac tggtattaaa catagttcca agactacctc
      481 ttattttaag agagtcgaag tgtctggtga tctatggggc cagtctagcc ctcttccaag
      541 tgtagggaga tatagtcaaa gtttgcttct ccgccgatga gtccgccctg cgtcggatag
      601 tccgattttt taccggcgaa gcacggctct cctaacccta tctaaagcga ataacttttt
      661 tcaacagggc cgcgtgccaa tgcaagagcg ataggcgctc tacgcgccaa tttgaccact
      721 taaaacaggt aaattgaggg gttgtaatgt gttgatgtaa caggctttta ttttaatgtc
      781 ttggcatatg tataatggta gtctagccct cctttcaaca aggagtactc atggaaacct
      841 acaatcatac atatcggcac cacaactttt cacataaaga cttaagtgat ctcaccttca
      901 ccgcttgcac attcattcgc agcgactttc gacgtgctaa cttgcgtgat acgacattcg
      961 tcaactgcaa gttcattgaa cagggtgata tcgaaggctg ccactttgat gtcgcagatc
     1021 ttcgtgatgc aagtttccaa caatgccaac ttgcgatggc aaacttcagt aatgccaatt
     1081 gctacggtat agagttccgt gcgtgtgatt taaaaggtgc caacttttcc cgaacaaact
     1141 ttgcccatca agtgagtaat cgtatgtact tttgctcagc atttatttct ggatgtaatc
     1201 tttcctatgc caatatggag agggtttgtt tagaaaaatg tgagttgttt gaaaatcgct
     1261 ggataggaac gaacctagcg ggtgcatcac tgaaagagtc agacttaagt cgaggtgttt
     1321 tttccgaaga tgtctggggg caatttagcc tacagggtgc caatttatgc cacgccgaac
     1381 tcgacggttt agatccccgc aaagtcgata catcaggtat caaaattgca gcctggcagc
     1441 aagaactgat tctcgaagca ctgggtattg ttgtttatcc tgactaattg ctttgatgtg
     1501 tgattttaaa cgctcaaatt tataaaacga ataatattgt caaccttgca ataatagaca
     1561 tagggacaac catgtataaa tttttaccct caggcgtctt cacaatagag ccatatagca
     1621 gtgggtcact tagtgggctt aatttttcca ttaaagataa tattaatatt gctcagtata
     1681 aaacatcata tggtagccca tcttggcaag taaacataag gctgccattt ataaggcact
     1741 gttgcaaaaa tgtggaggtg ataggggtac tacgccggaa ccccagattt ttccgtccgt
     1801 tcaaattatc cacggttgaa cagcttgatc ccgtccgccc gcagttgacc aacaggggaa
     1861 atatgcctgt acaaagtttg ccgggttatc ccaagttcct ggcatagcgt actgaccttt
     1921 gtttctgatt gtcccattga tgccattgcc agtcgcagtt tgactggcgt cattttataa
     1981 ggtcggccgc cgttccgccc acgggctctt gctgatgcca gacctgcagt cgttctttca
     2041 gcaatcagtt cgcgctcaaa ctccgccagt gcggcaaaga taccgaagac aagcttgcca
     2101 gcggccgttg ttgtgtcgat agtcgccccg tgaccggtca gcactttcag accggtcccc
     2161 ctcgcggtca ggtcgtgcac tgtattaatg agatgacgaa gatcacgacc gaggcggtcc
     2221 agcttccata cgaccagcgt gtctccgggt cgtagtgctt tcagacaggc tgtaagtcca
     2281 ggacgctctt ctcgtttgcc cgatgcccgg tcctcataaa aatgtgcggc atcaacacct
     2341 gcggcgatca gtgcatcacg ttgtaaatca ttcgtctgcg aaccatcagc ttttgacatc
     2401 cgaatatatc cgatgaacat atttcctctg tcacatatac gttcgattat gtgacattct
     2461 gatttgggta ccataatctg tcaacggtag tcacattacc cgtaatttaa attatgacac
     2521 gtaaaggttc tatgttaatg ataatgtgac aagcgcgttt aaataggcat aaggatcaga
     2581 gatgcctact aaaaataagc tcctcagtat tctttcggac gccgagcagg aagcgctcta
     2641 tggtctacct gatttcgatg atgcacagcg gctggagttt ctggcgctga atggatatga
     2701 actggcgctg gcctgcagtc gccgggggct tcacgctcaa atttattgca tcatccagat
     2761 cggagagcat gaaaaacctc ggggcagcca tcgaatgatg ccatctacag gggttaaaat
     2821 aaccaccatc atttcataac aatacctgct gactatgaag atctacgtca tcaaaatagc
     2881 agttcatgga gtcagtccga tggtctggcg tcggctgaga attgctgccg acacgtcact
     2941 ggccgcgctt cacttcattt tccagatagt gcagggctgg ggggacgacc atctccatca
     3001 atttcacatt tatggcaaag attacggtat ctcctacgaa ggaggcatcg gttttgtcga
     3061 taatccgttc cgggtcgtga ttgatgattt tgcttttgat gctggcgatc gctttaccta
     3121 tgaatacaat ttctttgagc actggcttca tgacattcgt gttgaggcca tttatgaaaa
     3181 ctctacgctg aaagcgccgt tttgtataag cggccatggt atgcccggag ccacagctgc
     3241 ggatgagttc gataaaaccc tggcgtttct tgaagctatc gttaatgcgg atgatgaaac
     3301 aacggtcggc gagatccgcc cttttgctga cgacctggat gctgtcaggt tcaaccgcca
     3361 caaaatcaac cggcaactga gcaggctcga ccttgcatct ccggtactgg agcctgaagt
     3421 tatctggctg ggccgtcgtc gctgactgat gtctataaag gtatacgttt tcagcatgcc
     3481 tctcagatcc ccgaaaaaat gtctataaac ctccctaaat cagtgtttat ggattattct
     3541 ttaaatctct atgatgttta aagaccttcc ggaggttttg cgtgcaatat gcctacatca
     3601 gggtaagctc ggccgatcag aatacggccc gtcaggaaga ggcattgtca aaggcgggtt
     3661 ttcagcctga taaaatttgt gttgagcatg ccagcgcgaa ggacacaaac cgcccggggt
     3721 tacaggaact cctggggcaa ttacgccctg gtgatacgct tctggttcat tccatcgatc
     3781 gcctttgccg gaatatgtcg gatatgtgcg ctgtcaccac ccggcttcgt gaccagggcg
     3841 ttacccttat ttttctgaaa gagcagctga cgttcagcgc cggcacaaac aatccgatgc
     3901 aggaactgca gctgcacatg atgtcggcat tcagccagtt tgaacgagcc ttactgaagg
     3961 aaaggcaggc cgacggcatc gccgcgaaaa aagcacgggg tgaaaaaaca gggcgccccg
     4021 gcgccgatat caaaaagatc caggaaattg acgcactcag aagcagaggg gtcaggctca
     4081 ggatcgcctg cgaccatgcg ggccttggcg tttccacata ttataagctt cgtcaccaga
     4141 tgaacaacca gtagccggga gatagtcatc caccacagca ggaggcaatg atgcaactga
     4201 cgctccagat agtcatcacc gatgaatcag gctccagtcg aacggaggaa ctgatgacaa
     4261 tccagaaatc aggggagacc cggaacgaca tcggattatc ggtgtcagaa tccaagctgt
     4321 tgctgaatac ggtccagcag tcggtggtcc agctgcaggc agacgaatat actcaacacc
     4381 atatccggtg ccctcactgc cttgctgcgc gcagaatcaa aggcaaacag aaaatacggt
     4441 accggacgct gtttggcgtt attccggtat ccgggcttcg ggtgtaccgg tgccgttgtg
     4501 aagagagtga tacaaagaca gtcagtttgc tcagcgactg ggccggcgat tattctcacc
     4561 cggcactgaa atatattgaa acccgctggg cctcgatgat ctcctatgaa atgacgactc
     4621 gtctgctgaa agatattctg ccggtgggcc acagcctgaa tgcctcaacg gtgaggaatc
     4681 atttatgcca ggtggcgcag cgtcttgacg ctgaggctga agctcattca ggttttcttt
     4741 ccggctgccc ccgcgactgg gggaacctgc ccaggccagg aaaaccgcaa ttaataacct
     4801 gagccaaagt aacaagaacc tcatctccga ccccatgccc gaagttatca tttatttttt
     4861 taaaaaaatc aacatcaata gcaataactg aagcccctga accctgcttg tgattttgta
     4921 ttttatttga aaaccccagt ctgttgttca cgccggttag gggatcttta agcgccacct
     4981 catttagaga atcaactctt tctatcatta tcttaatatg cgtaaaaagt gcctttttta
     5041 gtcggtcggc ttcgacatac caagcattga tacctttaat atcaactagc gaacccccta
     5101 tatctttagc attggtagat atagcaagct tttctaaagg aattgaaata cgggaagcaa
     5161 tgaaatatga aaaaagtgaa aatgtaataa ctattacaat tagcagaaca agtacactct
     5221 tagcataagt aataagaata gtagtcacgc tgtcagcgtg actataaacc aacacactcc
     5281 aagcagtatt tttcatatga gcataaccaa gaagatattt attccccgaa gaaaaaaaga
     5341 taccctcacc tctctcagac gaagttaact tcgatttcaa attatcatcc ataaccattg
     5401 gtcgaccaac agcactgtta tcgttattaa agatcacatt tccatcatca ctaacaatgc
     5461 taatttcagt gtcgcttttg aaaaaatgcc tgctcaaaac gtcgctaaat aaactctgtt
     5521 cctttagata tatagacccg ccgacatacc ctatataatt actattctta tcataaatag
     5581 gatgtgacaa aaaaataatc aaattcccag aagctgattt gtaaggtgcc gatataaatg
     5641 gttttttagc ctcaatcgcc aacttactgg cacttgaatt caagtgaact ccaactaaac
     5701 caagtgattc tggcgaagtc gccagaacaa cagcaccatc actaacaaca agaactgaat
     5761 taaacatacc agactgcaat cttaacctat ccgcctcatt tttaagtgag tcaatatcat
     5821 tagttgactc tatttttttt gcgccatacg ccaattcacg ttgagcaatt tcaatataat
     5881 tactcattac atctgacatt ttcatagcgt acgatgaatt agcatcaagc aagtcttttt
     5941 ctatattttc gcgtttaaaa accataataa cgacaatcag aaaaatagaa gtcaacaaaa
     6001 taccaccaac ggacaaggtt atgactatcg gacgaaggtg aggcttttta attctcataa
     6061 aaatacactc tatataatta aaaaattcca catttaccat aacatccctt gcccgcaccg
     6121 ccccggacgg gttcggcgcg aatgcggcgt cagcccggta aaaccggcag taaactcccc
     6181 gctaaaccgc gctttttgag ccagataaat ttccccaaga tgcatagcca tgcagccggg
     6241 ggatggcacc gcctttcggc ggggatctgc gccgaaagac ccgttttatc cggtttgtta
     6301 cagcgacgga ccgttgtacg tccgctggcg ctgcgatcgt tccagctcca gcgctttccg
     6361 gtgctgcgcc gcccgttcct gctcccggtg cgcctcgata ccattcagcc ttgcgacaac
     6421 cggcgcagct gctcgctcaa actctgcacc tgcctgctca agcccgtgac gcgctcgctc
     6481 agcgccgcgt tctcccgttg cataagacca gacatcgtcc gccattccgc gaaggcgttc
     6541 tcccactcgt ccagcctttt cgagtagtcc tgctgtagct gctctaatgc gctcagcaac
     6601 tgtttttcca gctccgtcat gtgctatttc cccgccagta tcatccagct cgaatcctct
     6661 ccgaaccgtc ccgcttccgg gttcaccctc acgcagctgc gtctctgctc gccgcaggtc
     6721 gagagctgca cgccgctgtt ccgctcggac agcatcgcct gcgtgctctt ctgctcccgg
     6781 atggtcgtgt aattgtcgag tatctgctga ctctgccacc acagaatgcc cgcgctcgat
     6841 gcgatcagca ggacggaaac caggacgatg gtcagccacg tctggctgac catacgcacc
     6901 atgcctttcg tgcgctggct catggctgag gacagcttcc ggtcgtggtc gaggatggcg
     6961 gcgctgattc tcttctcgct ttcgttcagt tccgctctga cagactgctc gtgctcgctg
     7021 aatgcggctt tcagcatctc gccggtactc tgctgctgcg ctttcgattt ctgctctaag
     7081 tccttcgcca gcgttaaaag actgctcata gatggctccc tttagtcgga tgtttcgccc
     7141 cccgtccggg tcggcaatgc tgatactgct tttcgtggtg cgtaccacct caaaacccgc
     7201 gttttccagc gcctcagtaa cgtcctgacg ggttttcagc tccccggacg aggctaaggc
     7261 cagcaaaccc cgggtgatcg cctgagctgc ctcctgcttc gtttccggca gcgcggacgg
     7321 cgtgaccagc gcccgccggt tttccggcgc attcgggtcg tgcagcccca gcctgccgtt
     7381 cacgatggtc tgccaggcat cgatgcgcgg acggtcagcg cggtcgtaat acggctggag
     7441 ccttttgccg gtcagcagct ccgtgttcgg gatcaggaag ttcagctcca gccgcccctt
     7501 gtcctggtgc tccacccaca gcacgctgta ctggtcttta tcgagtccgg gcatcagaac
     7561 acgctcgaag ctcgccatca gtttttcacg ctgaccgggc ggtaagtcct gttcggcaaa
     7621 cgacagcacc ccggaggtgt actttttggc gtagggcgag gcgtcgatta gctcccggac
     7681 ttcctccggt ttaccctgca gaacgctggc gccgtcgcgc ttgcggtcat tacccagcag
     7741 ataatccacc ggaccggcac cgccgccgcg ccctcgtggg tgaaatttaa cgatcatcgt
     7801 cagccccctt ttccagcaca gcgtgccgca ggcgctcaag tccggcatca atggccatca
     7861 gcgcagcgac aatctgtacg cgatcatgtc cggtaccacc accggcgtta acctgccggg
     7921 caatctgatt gaggttgttt cccataccgg caagttgacg aagcaacgcc ggcgagatcg
     7981 acggaagttt ggcggcacga gcaggtttct cgtcgagaca cgtctgccgc atccaggccg
     8041 cgagctgctt accgtcgcag cgatccagca gacgccggtg ctcgtcttca gttacccata
     8101 tcgtgagcat tttgctgcgt ttgtctgcca atccggcctc ctgataacgc cgggacggac
     8161 ggggaattat ttcccggtcg gcgcggtgtt ggacaagccg caggcgcgtc agtgcctttt
     8221 agcgggtttc ggggcgcagc cctgaaccag tcacgtagcg ctagcggagt gtatactggc
     8281 ttaaaatgta acatcgcaga aacatcaagc atagctgcca cataaagcag gtgaaaaatg
     8341 agattcgtat gcgtcagcag aagatgcact gccggagaaa tgccgcttcc tcgctcactg
     8401 actcgctccg ctcggtcgtt cggctgcggc gagcggtacc ggcttacggg cggggcggaa
     8461 atttcctgga agatgctagg aagaaactta acagggaagc gataaggcca cggcagagcc
     8521 gtttttccat aggctccgcc cccctgacaa gcatcacaga atctgacgct caaatcagtg
     8581 gtggcgaaac ccgacaggac tataaagatc ccaggcgttt ccccctggta gctccctcgt
     8641 gcgctctcct gttcctgcct ttcggtttac cggtgtcatt ccgctgttat ggccgcgttt
     8701 gtctcattcc acgcctgaca ctcagttccg ggtaggcagt tcgctccaag ctggactgta
     8761 tgcacgaacc ccccgttcag tccgactgct gcgcctcctc cggtaacttt caacttgatt
     8821 ccaacccgga aaggcacgac aaagcgccac tggcagcagc cattggtaac tgggaattag
     8881 tggatttaga tatcgagagt cttgaagtgg tggcctgact acggctacac tgaaaggaca
     8941 gtatttggta tctgcgctcc actaaagcca gttaccttcg gaagaaagtg ttggtagctc
     9001 ttaattccgg caaacgaacc accgttggta gcggtggttt ttttgtttac agggcatgag
     9061 cttacgacga catcgaaggg ataacaagag gatccgcttc ttgaaccctt ttccccacaa
     9121 aaaaacgcca cactagcgcg taaagcgtca tcaaaaaaac tcaaatagcg ctatatacaa
     9181 tcactttatt acgcccctct cccttggctt gataaagagc atcatcagca tttttcagca
     9241 aaaaatcgat cccaccaaga ggatcctctt gtgttgccac accagcagag acggtgaccc
     9301 gcaagttatt agggaaaaca gtactttcaa taacactcct aatacgctcc gcaacacact
     9361 ccgctgttac cacagatgta ttcggcagaa aaacaacaaa ctcttctcca ccaaaccgac
     9421 aaacaatatc ttcactacgg cagcaagaat tatccggttt cggcatgatg ctgatgtagt
     9481 cccgttttat cgtcatcacg aagctttctg ctatgccatt gctttccggg cttcgcactg
     9541 ctgtcgtaca aggctccagt cccagcaacc gggcgaacgc cggcactgtt ggcaactgcc
     9601 ttccgaagcg tttttccacc gcacccagca tgacatcctg caccgtttct ttgtcatagc
     9661 ctccggtgct cgctgcccaa tcaatgatct ccctgtcgca gcagtcctgc gcgaaggtca
     9721 cccgcagctt ttcgccatta tcacagcgga actcaaagcc atctgagcac cagcgccggt
     9781 tactttccgc tactgctacg cgccccttat gggcccgctt acggcaagga tcagcgggtt
     9841 tacgttcaag aagcagatta tgcgttctca taatgcgata cacccgcttt gcattaacca
     9901 caggcaggcc gtcccgctcc gactcccgtc gcagcagcgc ccacacacgg cgataaccat
     9961 acgtcggcag gtcagccacc gccatgttta tccgggacaa tacggtggta tcgtcagaac
    10021 ggggctgccg tctgcgatcc tgtcag
//
