LOCUS       NZ_CP043846            21978 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Staphylococcus epidermidis strain ATCC 12228 plasmid unnamed,
            complete sequence.
ACCESSION   NZ_CP043846
VERSION     NZ_CP043846.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN12721478
            Assembly: GCF_009873455.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis
  ORGANISM  Staphylococcus epidermidis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 21978)
  AUTHORS   An,Y.W., Cheong,H.-M., Choi,Y.S., Hwang,K.J., Kim,D.-W. and
            Yun,M.-R.
  TITLE     Development of domestic resource as an alternative strains of
            reference strains for Korea Pharmacopoeia
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21978)
  AUTHORS   An,Y.W., Cheong,H.-M., Choi,Y.S., Hwang,K.J., Kim,D.-W. and
            Yun,M.-R.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2019) Pathogen Resource TF, Center for Infectious
            Diseases Research, Korea National Institute of Health, Korea Centers
            for Disease Control and Prevention, #200 Osongsaengmyeong 2-ro,
            Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do 28160, South
            Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 455.15x
            Sequencing Technology             :: PacBio; IonTorrent
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 04:45:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,397
            CDSs (total)                      :: 2,313
            Genes (coding)                    :: 2,242
            CDSs (with protein)               :: 2,242
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 44 of 71
            Pseudo Genes (incomplete)         :: 42 of 71
            Pseudo Genes (internal stop)      :: 24 of 71
            Pseudo Genes (multiple problems)  :: 29 of 71
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP043846.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..21978
                     /organism="Staphylococcus epidermidis"
                     /mol_type="genomic DNA"
                     /strain="ATCC 12228"
                     /culture_collection="ATCC:12228"
                     /db_xref="taxon:1282"
                     /plasmid="unnamed"
                     /collected_by="Korea National Institute of Health"
     gene            join(21279..21978,1..509)
                     /gene="mobV"
                     /locus_tag="F1613_RS12360"
                     /old_locus_tag="F1613_12375"
     CDS             join(21279..21978,1..509)
                     /gene="mobV"
                     /locus_tag="F1613_RS12360"
                     /old_locus_tag="F1613_12375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002958641.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_071965886.1"
                     /translation="MKLAWNTQKNKMSDVKGKEMEQERKGRIKNDEIDLKRTNLNFDLI
                     EYERHLYHRVKDRVDYYKEQGSRVQKNSVVMYSNIITLSKEEADRMGETRTKHYFKTCK
                     DYFSERFGEANVVSAKVHMDESAPHMHLHFIPVNHQGRLSARTAMNRQAINHIHDELTT
                     HLCQQGFDVERGSTDDNKTYIQDIHEYKKKAKVLSELDQQIETKKQLLRDINDLHDEKE
                     HLTRDIQNLKRKNHFLQEDSQQAQEDIDLYKQLRTISRDDFKKDEEKYQKEIKAYEASL
                     SGLRMNYRDLNKRNQHLTTQNNQLEHHLDLLNARHQAMNDMVRNDTRILFAGLRCALKD
                     RNIELSAEIKYQRMPEVGIDPDTVDQGALTHAYQGDVSGIDHHIRKASAPIKKETENDL
                     ELE"
                     /name="mobV"
     gene            complement(1268..1423)
                     /locus_tag="F1613_RS12365"
                     /old_locus_tag="F1613_12380"
     CDS             complement(1268..1423)
                     /locus_tag="F1613_RS12365"
                     /old_locus_tag="F1613_12380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class phenol-soluble modulin"
                     /protein_id="WP_018113591.1"
                     /translation="MEHISKLGEAIVNTISASQSGDSAELAKSIVNIAANGIGVISDVA
                     KAFGLM"
                     /name="beta-class phenol-soluble modulin"
     gene            1931..2796
                     /locus_tag="F1613_RS12370"
                     /old_locus_tag="F1613_12385"
                     /pseudo=""
     CDS             1931..2796
                     /locus_tag="F1613_RS12370"
                     /old_locus_tag="F1613_12385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440631.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            3464..4030
                     /gene="lepB"
                     /locus_tag="F1613_RS12380"
                     /old_locus_tag="F1613_12395"
     CDS             3464..4030
                     /gene="lepB"
                     /locus_tag="F1613_RS12380"
                     /old_locus_tag="F1613_12395"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002503824.1"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA];
                     GO:0006465 - signal peptide processing [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="WP_018113588.1"
                     /translation="MKKEFKEWLIAIIVAILLLFLVNNFLFKPYTVSGLSMYPTFNNKD
                     KVVVSKISKSLNHLKSGDVIIFHQNSNNDFIKRLIGKPGDQIEYKNDKLYINKNYIKEP
                     YLDYNKKMNNSSENLTEDFNVSNIKGSKHKMIIPKDKYLVLGDNRTNSIDSRYSEVGLI
                     SKKQIVGKVILRFWPFNDMKYNFKR"
                     /name="lepB"
     gene            complement(4637..5122)
                     /locus_tag="F1613_RS12390"
                     /old_locus_tag="F1613_12405"
     CDS             complement(4637..5122)
                     /locus_tag="F1613_RS12390"
                     /old_locus_tag="F1613_12405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002455937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_020368224.1"
                     /translation="MKKFSKIVLASGIVLGFSVTPELFNATQAQAQESIEPHYNYDGYT
                     AYQSGFILDKNFKESLKYDNFTINGYQISKNPTGDNRINLYDQTLYGVSENKANGVFFS
                     LDGKSINKNTLIQNYGQPNSYSPTSAWGEEYMYKIGNKDVRFYIYNGYVIKCQIISE"
                     /name="hypothetical protein"
     gene            complement(5638..6003)
                     /locus_tag="F1613_RS12395"
                     /old_locus_tag="F1613_12410"
     CDS             complement(5638..6003)
                     /locus_tag="F1613_RS12395"
                     /old_locus_tag="F1613_12410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020368092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494365.1"
                     /translation="MKWLKIIILILSLVPIEFIGLFTDYQTGLLIGYIPFIIVAILISR
                     SIFKFGLKNNISIIISRCIGTFLSWECVHWFMNIYDSSDYFKPLTTDIFALFLGAIHFI
                     VIMLIYLVIYGFSHRNN"
                     /name="hypothetical protein"
     gene            complement(6133..6501)
                     /locus_tag="F1613_RS12400"
                     /old_locus_tag="F1613_12415"
     CDS             complement(6133..6501)
                     /locus_tag="F1613_RS12400"
                     /old_locus_tag="F1613_12415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002503834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="WP_002494366.1"
                     /translation="MKKILKILITSIIVIIITLTVWTFSVITYQEHKSEKIIDHVIERK
                     GWDKKIKNEKMSFNIMMGYAEKDIAFKDQPYSEYEYNVTPAPAPWTDDKEYKVWGETDL
                     QKKDSYYKYLLESEPYRK"
                     /name="DUF3139 domain-containing protein"
     gene            6605..7000
                     /locus_tag="F1613_RS12405"
                     /old_locus_tag="F1613_12420"
     CDS             6605..7000
                     /locus_tag="F1613_RS12405"
                     /old_locus_tag="F1613_12420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002502726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="WP_002494367.1"
                     /translation="MKRKYKITGIIFIVLLIVLTLIFSIVHHYANVQKHEEAKLKQKVH
                     HIFKQKGWEDKVKEEKNIFTFNTGDNDLQVTFKDEPYNTYTYSIDEDNKVYGNAVLKDE
                     YDKDFDSKKKYKEYLRKMHFEEKYDLK"
                     /name="DUF3139 domain-containing protein"
     gene            7234..7413
                     /locus_tag="F1613_RS12840"
     CDS             7234..7413
                     /locus_tag="F1613_RS12840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001829546.1"
                     /translation="MKSIVHFICLFIIFCIFGYVIDLIFFKEINIFLILESAFILSLLI
                     MPILKIVKEIEIEK"
                     /name="hypothetical protein"
     gene            7611..8060
                     /locus_tag="F1613_RS12415"
                     /old_locus_tag="F1613_12430"
     CDS             7611..8060
                     /locus_tag="F1613_RS12415"
                     /old_locus_tag="F1613_12430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494368.1"
                     /translation="MKKLLSVFIASLLVLTGLSFSSINQGNTASAKTKYKTTITYKGQK
                     YVYVGHYKHHFSKKEVKKVVKFSKGVHSGNKLVSAASKLSKNGYVKASSAIYKAFDFGL
                     KNELKGSYFYTAAKKGTGVTISYDMYTATTGPNHTIAKNFKHSYN"
                     /name="hypothetical protein"
     gene            complement(8220..8606)
                     /locus_tag="F1613_RS12420"
                     /old_locus_tag="F1613_12435"
     CDS             complement(8220..8606)
                     /locus_tag="F1613_RS12420"
                     /old_locus_tag="F1613_12435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494369.1"
                     /translation="MKKAIFSIIISLILVLTVTGCSNSSKEKPIKKSALEINPTSKAVN
                     ITINKKENNKPEKIGKVYRYKNNNAKEITNDGIKKDTKDTLIWKGVANKYDNVKDLLGE
                     SILYEVKYKNGDIKKFERKIKYTE"
                     /name="hypothetical protein"
     gene            complement(8626..8787)
                     /locus_tag="F1613_RS12570"
     CDS             complement(8626..8787)
                     /locus_tag="F1613_RS12570"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_162153024.1"
                     /translation="MNEREQRQKLNITLPPKLITNLDKVKTKYGINKSKQIENLISKYL
                     NEEYGNLE"
                     /name="hypothetical protein"
     gene            complement(9580..10098)
                     /locus_tag="F1613_RS12425"
                     /old_locus_tag="F1613_12440"
     CDS             complement(9580..10098)
                     /locus_tag="F1613_RS12425"
                     /old_locus_tag="F1613_12440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_023567445.1"
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGVTVHHS
                     TVYRWVQEYAPILYQIWKQKHKKAYYKWHVDETYIKIKGKWCYLYRAIDADGHTLDIWL
                     RKQRDNHAAYAFIKRLIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRSLQIYGFSPC
                     REISIMLAS"
                     /name="IS6 family transposase"
     gene            complement(10218..11129)
                     /locus_tag="F1613_RS12430"
                     /old_locus_tag="F1613_12445"
     CDS             complement(10218..11129)
                     /locus_tag="F1613_RS12430"
                     /old_locus_tag="F1613_12445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276756.1"
                     /note="predicted Zn-dependent protease with a strongly
                     conserved HExxH motif; predicted Zn-dependent protease with
                     a strongly conserved HExxH motif; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing putative Zn-dependent
                     protease"
                     /protein_id="WP_020368409.1"
                     /translation="MYKINIVRSDKVYLGLLDTEYENKSKYFKDNLLKYFKEKFEIQNI
                     PFESDNFRFDALQFLNMTHISPEAFNTNYRSEVALLNDAFWNDCKLYIEDGIEQFEKNG
                     IESHIDKYTFTVLLGDSKKPTMYLNNNYGGDGGIPGYIFISLVPNQYTISRIKSAIAHE
                     INHNIRYQYIKWDGGSLTELIISEGLAENFVEKMYGTKYLGPWVTEIDWDQQNNKIKNT
                     IKENLDINNMFEAMPYLYGDEITRMQGGVPVGLPHAAGYTCGYYLIKYYLEKTQRTIEE
                     ATIKSSDEILKEVNDFWNTNII"
                     /name="DUF2268 domain-containing putative Zn-dependent
                     protease"
     gene            11216..11734
                     /locus_tag="F1613_RS12435"
                     /old_locus_tag="F1613_12450"
     CDS             11216..11734
                     /locus_tag="F1613_RS12435"
                     /old_locus_tag="F1613_12450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_023567445.1"
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGVTVHHS
                     TVYRWVQEYAPILYQIWKQKHKKAYYKWHVDETYIKIKGKWCYLYRAIDADGHTLDIWL
                     RKQRDNHAAYAFIKRLIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRSLQIYGFSPC
                     REISIMLAS"
                     /name="IS6 family transposase"
     gene            11849..12223
                     /locus_tag="F1613_RS12440"
                     /old_locus_tag="F1613_12455"
     CDS             11849..12223
                     /locus_tag="F1613_RS12440"
                     /old_locus_tag="F1613_12455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494371.1"
                     /translation="MKKIVYILGTIIVLGFCYFYVNLIFFDSWTRYSAEKEINNYISNH
                     DTKKLKEISANNKTYQLLKHAKHVTIKGDTDNQGGGHIGYFTSTINGKEGALFVHLNFG
                     LFPEIPKVTKLEVFDKNIYE"
                     /name="hypothetical protein"
     gene            complement(12814..13266)
                     /locus_tag="F1613_RS12445"
                     /old_locus_tag="F1613_12465"
     CDS             complement(12814..13266)
                     /locus_tag="F1613_RS12445"
                     /old_locus_tag="F1613_12465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494373.1"
                     /translation="MPKKQSSKEKILTVRVSQAQYKKIQDLAYIRSMNVTEYIRQTAVG
                     NRIKPTVIEYPKEQITMDDSNSKNNTNNLYKVIEHLEEDNEALKSDRDALRQRHDQLED
                     DIEQYKRENEIFHRLLEHFDSTAFMNFNTYRDDRPLKKEIKRLKEH"
                     /name="hypothetical protein"
     gene            13721..14929
                     /gene="mobV"
                     /locus_tag="F1613_RS12450"
                     /old_locus_tag="F1613_12470"
     CDS             13721..14929
                     /gene="mobV"
                     /locus_tag="F1613_RS12450"
                     /old_locus_tag="F1613_12470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002958641.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_071965886.1"
                     /translation="MKLAWNTQKNKMSDVKGKEMEQERKGRIKNDEIDLKRTNLNFDLI
                     EYERHLYHRVKDRVDYYKEQGSRVQKNSVVMYSNIITLSKEEADRMGETRTKHYFKTCK
                     DYFSERFGEANVVSAKVHMDESAPHMHLHFIPVNHQGRLSARTAMNRQAINHIHDELTT
                     HLCQQGFDVERGSTDDNKTYIQDIHEYKKKAKVLSELDQQIETKKQLLRDINDLHDEKE
                     HLTRDIQNLKRKNHFLQEDSQQAQEDIDLYKQLRTISRDDFKKDEEKYQKEIKAYEASL
                     SGLRMNYRDLNKRNQHLTTQNNQLEHHLDLLNARHQAMNDMVRNDTRILFAGLRCALKD
                     RNIELSAEIKYQRMPEVGIDPDTVDQGALTHAYQGDVSGIDHHIRKASAPIKKETENDL
                     ELE"
                     /name="mobV"
     gene            15602..16468
                     /locus_tag="F1613_RS12455"
                     /old_locus_tag="F1613_12475"
     CDS             15602..16468
                     /locus_tag="F1613_RS12455"
                     /old_locus_tag="F1613_12475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440631.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_077431477.1"
                     /translation="MSGETVIYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLHL
                     SFDELKELSNYNPETRNINRFVDDLQRVYDKMLDIRYTIRTETKIKKFVLFYKYEIDIS
                     ERYLEIATSPDLKYILNSITNNFTKFELKEMTHLKSTYAKNMFRMLKQYKHSGYMKIRV
                     EDFRERLDIPNSYRMSNINQFVLTPIIRELSTIFNNLKINKIKAKKGRKIEWLEFIFDA
                     EKRIHNKRQPQMTNVGKQRQYINREKTPEWLNEGRLGQFQEIHNEDTKLKQDREAFQRQ
                     LEEKWED"
                     /name="RepB family plasmid replication initiator protein"
     gene            17084..18013
                     /locus_tag="F1613_RS12460"
                     /old_locus_tag="F1613_12480"
     CDS             17084..18013
                     /locus_tag="F1613_RS12460"
                     /old_locus_tag="F1613_12480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="WP_077431479.1"
                     /translation="MNKEEYLKIIQKETKKINTDEKEDILSKYESYFINGYKNNKNDEE
                     IIKELGDPVKIAKEINAVNSLYKVENKKSVKSIFSAAFSIMELSILNLILIISIFYTMT
                     QVHNNHKVSGETILTLSTWLFAFWGVMIITSFLVRDFSQGTSQLYLNSSKNRVKYFISQ
                     LISILIASVIVFLTLYVFVLIMQNIGDGEPLKNEVVGKALGIYILLFLFYGLFLFLITL
                     LVKSSSLVFSIGVFLILIIPIATNLVPLIPEYGDEVRKALKYIPFNFLINNVWLGSLKL
                     NGWQTFISIASVILLAIIDFFTISKRDY"
                     /name="DUF1700 domain-containing protein"
     gene            complement(<18247..18382)
                     /locus_tag="F1613_RS12730"
                     /old_locus_tag="F1613_12485"
                     /pseudo=""
     CDS             complement(<18247..18382)
                     /locus_tag="F1613_RS12730"
                     /old_locus_tag="F1613_12485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829553.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            <19030..19353
                     /locus_tag="F1613_RS12470"
                     /old_locus_tag="F1613_12490"
                     /pseudo=""
     CDS             <19030..19353
                     /locus_tag="F1613_RS12470"
                     /old_locus_tag="F1613_12490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(20405..20824)
                     /locus_tag="F1613_RS12480"
                     /old_locus_tag="F1613_12500"
     CDS             complement(20405..20824)
                     /locus_tag="F1613_RS12480"
                     /old_locus_tag="F1613_12500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002511307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002502136.1"
                     /translation="MPKKQNSKEKILTIRVSQSQYEKICALADIREMNVTEYIRHTAIG
                     NRIKPTVIEQIKESSEVSELFKKDNEALKSNNQALQHHIHQLEDEIDQLRQENDVFHHL
                     LQHFDSTAFLNFNTYRDDRPLKNAIKRLKEQYKSK"
                     /name="hypothetical protein"
     Typing          1932..2796
                     /name="rep_cluster_1439"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.769"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15603..16360
                     /name="rep_cluster_1448"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="85.151"
                     /coverage="88.0"
                     /evalue="0.0"
     Typing          4..506
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="97.619"
                     /coverage="100.0"
                     /evalue="7.84e-103"
     Typing          13650..14926
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.122"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          21208..21977
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.444"
                     /coverage="100.0"
                     /evalue="1.62e-166"
ORIGIN
        1 aaaatcattt tttacaagag gattctcaac aggctcaaga agatatagac ctatacaagc
       61 aactgagaac gatttctagg gacgatttta aaaaagatga ggaaaagtac caaaaagaaa
      121 tcaaagcgta tgaggcgtct ctgagcggcc ttagaatgaa ttaccgagat ttgaacaagc
      181 gcaatcaaca tttaacaaca caaaataatc aactcgaaca ccatttagac ctgttaaatg
      241 cacgtcatca agcgatgaac gacatggtaa gaaatgatac acgtattttg tttgcgggac
      301 ttagatgtgc attgaaagat aggaacattg aattaagcgc agaaattaaa tatcaacgta
      361 tgccagaagt cggtattgat cccgatacgg tggatcaggg ggctttaaca catgcatatc
      421 aaggtgatgt gtcagggata gaccatcata taagaaaggc atcagcacct attaaaaaag
      481 agacagagaa tgacttagaa ttagaataag tcaataaaaa taagcactca ggcaagtatg
      541 atacttgttt gagcgcttat ctcaatgaaa agagtaagta aaaacttaat aagctggcga
      601 cacttattaa gagcaataat aactttaatt actgaattag tagactagtt cagtaattag
      661 gaacgatacc tttgtatttc tatattatta taagaattcc aaggtagcaa tgatattgat
      721 ttaatatgag caaattgata ttggaagcaa aagaaaccca ctcaaacgaa cgagtgggtt
      781 ttgaaaaatg atacgtatta acttgataaa attaatcatt ttatagttta aagaaaagga
      841 atgcataatt atagtaacac aaattaatgt ttgttacact agtagtgctg ctcaatatat
      901 aaagtagtaa accataacta ttcttcgcat ctcttgttaa aaagttaatt ttttgctttg
      961 tacaaggaaa agcactcaaa attgagtgct tttttcatat taaaattaaa ctttaaaaat
     1021 taagacagcg acacatatca gtgtcgctgt cttaagatat attatatgag ttcaaaagat
     1081 atatagctat tgtagcataa tagtgttttt attaaaaaac aagacgaaat agtttgaatt
     1141 actaaataac ttatgtctta aatcttttaa tttatttaag atacgttgtt attaagaaaa
     1201 taaaaaaaga tataaatcaa ctaaataatt gatttatatc ttcatatgta ttgatttaaa
     1261 atacttacta cattaaacca aacgctttag caacgtctga tattacacca ataccattag
     1321 ctgcaatatt aacaattgat ttagctaatt cggcactatc tccagattgt gatgctgaaa
     1381 tagtattaac aatagcttca cctaattttg aaatatgttc catgaaaaac aaacctcctt
     1441 acatataaaa tcattactca aataaaataa catatattac gataattctc ttctactttt
     1501 aaataattgt aattaaattt acgttttctt aaaaataaat aaagggattg caatgttgtt
     1561 actattaaaa ttaataaaaa aactttgaat ataataatag ctattttaca tggaattttt
     1621 taatatcttt ttataaatct ttttataaac ctttttagaa gtcgtttgag ctttagagcc
     1681 acagcttatt tgagatgctt aaggagtagt tttgccacat aaaaggagta gttttgccac
     1741 ataaaaggag tagttttgcc acataaaagg agtagttttg ccacataaaa ggagtagttt
     1801 ttattataaa ccttcttttg ttaattgaca ttgttatcaa agtgttttaa cgtgaaaata
     1861 tcaattcaat aaggagtatc ataaaaaaat atgctcctta ttgaaataat tatgttgagg
     1921 tatctatata atgacgggag aaacagtagt atacaaaaac gatttgaatt tagttccttt
     1981 aagaaaattc accagtactg aaattaattt atttttgcca tgtgtaataa acttaaggaa
     2041 aaagaaacta acacacttca tttatctttt gatgaattga aagaattgag taactatagt
     2101 ccgaaaacac gtaatattaa tagattcgtt aaagacttgg atgatgtata taagaaaatg
     2161 ttggaactaa caattagata cgaagatgat gaggttatag aaagatttat tttatttaat
     2221 cattatagaa ttcataaaaa agatcaatac ttagaaattt caacttctcc taatttaaag
     2281 catatactta attcaattac tagcaacttt actaaatttg aattaaaaga aatgacaaat
     2341 ttgaaatcta catattcaaa aaacatgttt agaatactta aacaatataa acacactggt
     2401 tatatgaaaa ttaaaattga tgattttaga gaacgcctag atatccctaa atcttataga
     2461 atgacagata ttaataaaaa tgttttgaag cctattgtta cagagttaaa cgctattttt
     2521 aacaatcttc acattaataa aatcaaggct aaaaaaggac gtaaaattga atggctggag
     2581 tttatctttg atcctgagaa acgcattcac aataaacgac agcctcaaat gaccaatgta
     2641 ggtaaacagc gtcaatatat caatcgtgag aaaacaccag aatggttaaa tgaaggaaga
     2701 ttaggacaat ctcaagaaat acataatgaa gattcaaaat taagacaaga tcgagaggca
     2761 tttcaacgtc aattagaaga aaaatgggag gaataataac ttaaatgagc tacatctata
     2821 ttttgctttt atttccttta ataatgggat ttttcttatc actaaaagag aaaaagtatg
     2881 ataaaaaatg actaattcac tattgtaaag aaaatacaga attttatgag taaaacttgt
     2941 aattttattg caagtgaaga aactacagta tatactgaaa ctaataaata ttgaactcat
     3001 atatcaccga accccaacct actgacatag gttgggttct ttagtggtaa ggctatcttg
     3061 acttatttat tgcggttgtt tagccaaaac atgaaaatcg caacaccgca tcctactata
     3121 atttgaataa agcattaaaa atggccactc aacaatttga gtggcattga aatcgttaag
     3181 gagttactta cgttaaaaaa attaatgtta gttagggaca attatatgtt ttcactttaa
     3241 cacttattta tatttaactc actcaaaaaa tatttaacgc tggaaatttt tgcctttttt
     3301 gaaacgagtg gaacgagttc attctgttct tgatagtaaa ttttattatt tcaataaaga
     3361 aaagacatca taaataatga actacttttg gtaggatatt aaaaatataa gtgataacct
     3421 aaaataggat aaagtttata aaatctaaaa aggaaattat gtaatgaaaa aagaatttaa
     3481 ggaatggtta atagccataa tagtagctat attattatta tttttagtaa ataatttttt
     3541 atttaaacct tatactgtat caggattatc aatgtatcca acgtttaaca ataaagataa
     3601 agtagtagtc agcaaaatat ccaaatcatt aaatcactta aagtctggag atgttattat
     3661 atttcatcaa aatagcaata atgactttat aaaacgattg attggtaaac caggagatca
     3721 aattgaatat aaaaatgaca agttatatat caataaaaat tatatcaaag aaccttacct
     3781 tgactataat aaaaaaatga ataactccag tgaaaattta acagaagatt ttaatgtatc
     3841 aaatataaag ggatctaaac ataaaatgat aatacctaaa gataagtatt tagttctcgg
     3901 agacaatagg acaaacagta ttgatagtag atattctgag gtggggttaa tatctaaaaa
     3961 acaaatcgta ggaaaagtta ttttaagatt ttggcctttt aatgatatga agtataattt
     4021 taagcgatga atgataaaaa agataagtta taaagctagc ttgagatatt gttgacgatt
     4081 acataattag ttcgttcgaa tatctattta attttacaaa tctatactta caagatatac
     4141 tgaaagtaac aaatattaag tgcatcaaaa caccaatccc ccaacctatg ccagtagatt
     4201 gggggatctt ttagtgttga ctatgtcgtc ttatttttta ttacgttgtt ccagccaata
     4261 tttaaacaac gtaacactgc actctactat aataggtgct attataaaaa caaatattaa
     4321 gtacatcatt acacctcctt ccgtcgaatc tatcgccgga agtaagacga cttcaatagt
     4381 ataacaaaaa tttttaattt aaaacgatag tttaggactt gccatatgaa taaagataca
     4441 aaagttcact tgatgaaaaa gaatgaaaac gcgtcgttaa agggatgtat aaaagttgta
     4501 taaagggaaa tgatgacaaa tagggacaaa cgctgaaatg acggcgtttg tccctaatat
     4561 gttagttaac ataatataaa gaaaacatga agtaagcaaa cttgcaactt acctcatgtt
     4621 ttatacctaa aatgtcttat tcacttataa tttgacattt aatcacatag ccattgtaaa
     4681 tataaaatct gacatcttta ttaccaattt tgtacatata ttcttcaccc catgctgaag
     4741 tcggagagta agaatttggt tgaccataat tttgaattaa agtattttta ttaatagatt
     4801 ttccatcgag agagaagaaa acaccattag ctttattctc agatacacca taaagtgttt
     4861 gatcgtataa atttattcga ttgtcaccag ttggattctt cgatatttga tagccgttga
     4921 tagtaaaatt atcgtatttc aatgactctt tgaaattttt gtctaatata aatccacttt
     4981 gatacgcagt ataaccatca taattataat gaggttcaat agactcttgc gcctgtgctt
     5041 gcgttgcatt aaatagttcg ggcgttacag agaaacccaa aacaatacca ctagctagaa
     5101 caatttttga aaatttcttc ataaaaaacc tcctaaatat ttataattca tctatcatta
     5161 ttacaaatat attacaaaaa atcatccgtt attacaaaaa cattacaaaa agtttatcta
     5221 aagttaatgc tttatcaact tctaaattta aaacaccaac tattttttcg tgactatcat
     5281 agttaaactc tgtttaatta tggtttcttt ttatgtagtg cctatagaca aattggacat
     5341 ccaaaaagct ttcatactga aagtaaaatt actcgcaata atctaatgat cttaatttca
     5401 attttaaagg gggatttcaa agtattataa atccaattta tagtttaata cctagaactt
     5461 tctgtctgct ctcaagacaa gaagaagctc gtttctaaaa gcaaaaaaac aagccgagat
     5521 ttcggcctat tttctttaca taattaacta ttatgggtag tgcctttgta taaatactca
     5581 aaaacacaaa cattgttaaa ttaatctttg tgtcctttaa tataagtaac ataatagtta
     5641 attattgcga tgagaaaaac catagataac taaatatata agcataataa ctatgaaatg
     5701 aatagctcct aaaaataatg cgaaaatatc tgtagtaaga ggtttaaaat aatctgatga
     5761 atcgtaaata ttcataaacc aatgaacaca ttcccaagaa agaaatgttc caatacatct
     5821 acttattata atacttatat tattttttaa gccgaattta aaaatagatc tacttattaa
     5881 tatagcaact attataaatg ggatgtaacc tattaataaa cctgtttgat aatcagtaaa
     5941 taatccgata aattctattg gaactaaaga taaaattaat ataatgattt ttaaccattt
     6001 cattttaaaa tttctctttt caatattatt tttccttcaa tatcatttta ttaatataat
     6061 taggtaaaag tctacgctgt ctttaagtga tagatgaatg atctctattt tttattatgt
     6121 tatacattta tattattttc tgtaaggttc tgattctaaa agatatttat aataggagtc
     6181 tttcttttgt aaatctgttt ccccccatac cttatattct ttatcatctg tccatggtgc
     6241 tggtgctggt gtcacgttat actcatactc actatatggt tgatctttaa aagcaatatc
     6301 tttttcagca tatcccatca taatattaaa actcattttt tcatttttta tttttttatc
     6361 ccaaccctta cgttctataa cgtgatcgat gattttctca ctcttatgtt cctgataagt
     6421 aatcacacta aaagtccaaa ctgttaaggt aataatgata acaataatag aagttattaa
     6481 tatttttaag attttcttca tttttgtata attcctcttt tttaataatt tttatgataa
     6541 atatgtatta ttgtatttaa ttttacaaaa tattaattaa ataaatttac ttaaggagac
     6601 taatatgaaa agaaaatata aaattacagg tatcatcttt atcgttcttc ttatcgtttt
     6661 aacattaatt tttagtatag tgcaccatta tgctaatgtt caaaaacatg aagaagctaa
     6721 actaaaacaa aaagttcacc atattttcaa acaaaaaggt tgggaagata aagttaaaga
     6781 agaaaaaaat atatttacgt tcaatactgg agataatgat ttacaagtca cttttaaaga
     6841 tgagccttat aatacgtata catattctat tgatgaagac aataaagtat atggaaatgc
     6901 tgttttgaaa gatgaatatg ataaagattt tgatagtaaa aaaaagtaca aagaatattt
     6961 aagaaaaatg cattttgaag aaaaatatga tctgaaataa aaaagcaagc gactacgata
     7021 attgatagtc gcttgctttt tagtgttctt tcaatttgtt taatgctttt ttatgattcg
     7081 ttttctatct tgtaatttgg aggcttatat atgccatttt aaaagcatat gcgcgtcttt
     7141 aatatgaaat atactaaaat tacctatatg atattaaatg aaaagcctgt ataaagttta
     7201 aaatagctta gaaagcaaaa aggagtatta gcattgaaat caattgttca ttttatttgc
     7261 ctctttatca tattttgtat ttttggatat gtgatagatt taatattttt taaagaaata
     7321 aatatttttc tgattttaga atcagccttt attttatcat tactaatcat gccgatatta
     7381 aagattgtaa aagagataga aattgaaaaa tagaactggt aaataccatt ttctatactt
     7441 aatgtttaat aaaaataggc tactaaaatt cagttaataa agatccatct ttattaactg
     7501 aattttaaaa aatatatata gtgttaattt ttttaattaa agtagttata acttaattta
     7561 tatgataaag tcatatttaa acatataaat attttacagg aggtcttttt atgaaaaagt
     7621 tactttcagt ttttattgca agtttattag ttttaaccgg attatctttt tcttcaatta
     7681 atcaaggtaa tactgcgagt gctaaaacaa aatataaaac aactataact tacaaaggtc
     7741 aaaaatatgt atatgttggt cattataaac accatttttc taaaaaagaa gttaaaaaag
     7801 tagttaaatt ttctaaagga gttcattcag gaaacaaatt agtatctgct gctagtaaac
     7861 ttagtaaaaa tggttatgtt aaagcatcct cggctattta taaagccttt gattttggat
     7921 tgaaaaatga attaaaaggt agctattttt acacagcagc taaaaaaggt acaggcgtaa
     7981 caatttctta tgatatgtat actgcaacaa caggtccgaa ccatactata gctaagaatt
     8041 ttaaacatag ttataattaa ataaatgtga ggggaaggat taatccttcc cctcacattt
     8101 attttcaagc ttttttgaac ggttgaattt tagaccataa tttatgaatt catagatatt
     8161 agataatatt tcagctatta ttcttaaaat attttccatt atcatcacta ctttcaattt
     8221 tattcagtat atttaatttt tctctcgaat ttttttatat ccccattttt atatttaact
     8281 tcataaagaa tactttctcc taataaatct tttacattgt cgtatttgtt tgctacacct
     8341 ttccaaatca atgtatcttt agtatctttt ttaataccgt cattagtaat ttcttttgca
     8401 ttgttatttt tatatcgata cactttccca attttttcag gtttgttatt ttctttttta
     8461 tttattgtaa tattaacagc tttacttgta ggattaattt ctaatgcact ttttttaatt
     8521 ggtttttctt tagaactatt actacatcca gtaacagtta gaactaaaat aagagaaata
     8581 ataatactaa atattgcttt tttcattcta atcatccttt tttgcttatt caagattacc
     8641 atattcttca tttaaatatt ttgatattaa attttcaatt tgtttagatt tattaatacc
     8701 atattttgtt ttaactttat ctaaattagt tattaattta ggaggaagag taatatttaa
     8761 cttttgtctt tgttctcttt cattcaaacc cacaacactc tccttttatt tatgcgtata
     8821 aagtagcatt acatgcgtac aaagtcaagt ttgtacccat aaaagaagta tagtatagtt
     8881 tgttttttac tttatggagc tattataatt acgacaaacg ataaaagaaa aacaattttt
     8941 tcctctcaaa aaagccctat agttttcaac taagaataaa tgagcaaagc aaatggtaag
     9001 atagtccttc agctatgctg aatactacct taggcggtaa tggatttcct tatgctcttt
     9061 aaaatacaaa agttacatta tatacctact ttttcaggtt ttagcttttt tctaagaaga
     9121 acaattgaga taaaaaatat attttccttt ctgaaagtgt tgagaaagaa attttaaaat
     9181 gatttatagc ctatctgttg aacaaaaaag tttttagtca ttttttaata aaatgttcta
     9241 gaaagggctt aaaatgcaaa ataaaaagac tactcaaaaa atgagtagtc tgaagaatag
     9301 tttttgatgt attaaatgaa agggagtact acattaatca tatcacacgc atttataccg
     9361 agaaaattta ttgatgttga gaagaaccct taactaaact tgaagccgaa tgtcggcata
     9421 gcgtaagcta ttaagccgac gattcgataa gtttagggat tgttaaagat tcggaggttc
     9481 aacgtcaata aagcaattta aaactatagt taaaataggg ttctgttgca aagtcagaaa
     9541 gataagtata taaccttatg tttaaaataa tacgtcatat taactcgcta gcatgatgct
     9601 aatttcacgg catggtgaaa acccgtagat ctgaagagac ctgcggttct tcttatatag
     9661 tccataaata cattcaatgc ctttgattgt attctttgcc gtattgatac tttgataact
     9721 tattttcctt actttgataa gacgcttaat aaaagcgtat gccgcatgat tatctcgttg
     9781 cttacgcaac caaatatcta atgtgtggcc gtctgcatca atcgcacgat ataaatagca
     9841 ccatttgccc ttaattttga tatatgtctc atcgacatgc catttataat aagctttttt
     9901 atgcttttgc ttccaaattt gatacaaaat cggtgcatat tcttgaaccc aacgatagac
     9961 tgttgaatga tgaacagtga caccacgttc tcttaatatt tcagatatat cacgataact
    10021 caatgcgtat cttaggtagt agccaacggc tacagtgatg acatctttat cgaattgttt
    10081 atatctgaaa tagttcatac agaagactcc tttttgttaa aattatacta taaaattaac
    10141 tttgcaacag aaccttgctt aacatattcc tatatgtaac gttctttttg atacacctgt
    10201 tatttcaata atgtctttta aattatattg gtattccaga aatcattcac ctcttttaaa
    10261 atttcatctg atgatttaat agtagcttct tctatagtac gttgtgtttt ttctaaatag
    10321 tattttataa gataataacc acacgtatat ccggctgcat gtggtaatcc aacaggcact
    10381 ccaccttgca ttcttgtaat ttcatctcca taaagatatg gcattgcctc aaacatatta
    10441 ttaatatcta gattttcctt tattgtattt ttgattttat tattttgttg atcccaatca
    10501 atttcagtta cccatggccc taaatatttt gttccataca ttttttccac aaaattttct
    10561 gcgagtcctt ctgaaataat taattcagtc agagatccgc catcccattt aatgtactga
    10621 tatctaatat tatgatttat ttcgtgagca attgcacttt taatacggct tattgtatat
    10681 tgattgggta ctaatgaaat gaatatataa ccaggtatcc caccatctcc accataatta
    10741 ttatttagat acatcgtggg ttttttactg tcccctaata atacagtaaa cgtatattta
    10801 tcaatatgtg attcaattcc atttttctca aattgttcta taccatcttc tatatataac
    10861 ttacaatcat tccaaaaggc atcatttagc agtgcaactt cactcctata atttgtatta
    10921 aatgcttctg gcgaaatatg agtcatattt aaaaattgta atgcatcaaa tctaaagttg
    10981 tcactttcaa aaggtatgtt ctgaatttca aatttttctt taaagtattt tagaagattg
    11041 tctttaaaat atttcgactt attttcatat tctgtatcaa gtaaacctaa atatacctta
    11101 tctgatctaa ctatatttat tttatacata tttatccctc catatcacta acaataaaag
    11161 gttctgttgc aaagttaatt ttatagtata attttaacaa aaaggagtct tctgtatgaa
    11221 ctatttcaga tataaacaat tcgataaaga tgtcatcact gtagccgttg gctactacct
    11281 aagatacgca ttgagttatc gtgatatatc tgaaatatta agagaacgtg gtgtcactgt
    11341 tcatcattca acagtctatc gttgggttca agaatatgca ccgattttgt atcaaatttg
    11401 gaagcaaaag cataaaaaag cttattataa atggcatgtc gatgagacat atatcaaaat
    11461 taagggcaaa tggtgctatt tatatcgtgc gattgatgca gacggccaca cattagatat
    11521 ttggttgcgt aagcaacgag ataatcatgc ggcatacgct tttattaagc gtcttatcaa
    11581 agtaaggaaa ataagttatc aaagtatcaa tacggcaaag aatacaatca aaggcattga
    11641 atgtatttat ggactatata agaagaaccg caggtctctt cagatctacg ggttttcacc
    11701 atgccgtgaa attagcatca tgctagcgag ttaatatgac gtattatttt aaacataagg
    11761 ttatatactt atctttctga ctttgcaaca gaaccacttt aatttaccat aaaaacttaa
    11821 atattttgag gagataagga gtctttaaat gaaaaaaata gtttatatac ttggtactat
    11881 tatagtttta ggcttttgtt atttttatgt aaatttaatt ttttttgata gttggacacg
    11941 ttattctgct gaaaaagaaa taaataatta tatttcaaat catgatacaa agaaactaaa
    12001 agaaatatcc gcgaataata aaacatatca acttttgaaa catgctaaac atgtgacaat
    12061 aaaaggagat acagataatc aaggtggagg tcatataggg tattttacta gtacgattaa
    12121 tggtaaagaa ggagcgcttt ttgtacatct taattttggt ttgtttcctg aaattcctaa
    12181 agtaaccaag ttggaagttt ttgataaaaa tatttatgag tagcataatt gctactcatt
    12241 tttcgtgtta gttattctgg ttctgttgca aagttagaaa aatatagcta attacgtcca
    12301 tatagcatta agcttctatg ctatgataat cgttagaaat ctggctaaga atctggagtg
    12361 tttttatgat ttttttaaga gaaaaaatag tcatgaaata tacaaaaaaa tcatgtatat
    12421 tttgttaaat agtacagtga tagcatttat attattgcta attgtgaaat taatatttga
    12481 tttccttttt tagactatat tcatattttt tcagatttgt atttttattg gggttaatta
    12541 ttggtagtat cccagatttt atagaaaaga aaggttaatt ttatgttatt aaaaaataag
    12601 atttattcag gcattattat tgttattttt atagtttgtt tgattatagg attgaatgaa
    12661 aatatcattg gaaatccttt aggagaaaaa atattttatt tattaggttt tctatttttt
    12721 gtattattaa ttattggtac aacaaaaaat agaaagcatt aatgtcttct ttttgcccca
    12781 tttcttacga taaacatttt ttgagtagcc tttttaatgt tctttcaatc gtttaatttc
    12841 tttttttaat ggtctatcat cacgatacgt attaaaattc ataaatgcag tactatcaaa
    12901 gtgctctaac aagcgatgaa atatctcatt ctcccttttg tattgttcta tatcatcttc
    12961 aagttggtca tgacgttgtc gaagtgcgtc tctgtctgat ttgagtgctt cgttgtcttc
    13021 ttctagatgt tcaataactt tatacaaatt attcgtatta ttcttagaat tagaatcatc
    13081 catcgttatt tgctcttttg gatattcaat caccgtcggt ttaatccgat tacccacagc
    13141 tgtttggcgt atatattctg tgacattcat actacgtatg taggctaaat cttgtatctt
    13201 tttgtattgc gcttgactga cacgaacggt taagattttt tctttcgagc tttgtttttt
    13261 tggcattgaa tcacctcata attaatatat gataagcata catatgtgtg cttatcttta
    13321 tattaatata acatacatat gtatgttaat aaatatgtat gattcgaggt gttgtgagct
    13381 aacatttggc atacatatta tcaaacatat ttgtttgata atgcgtatgt catttgttag
    13441 ctatagaacg gaattcaaaa atatattttt gaatgtagtg atggcctcgc cagagcgaag
    13501 ataactctta catttgaatg taagagtata tcgagctata ctctcattgc ggaatcagcc
    13561 tcacatgttt gaggcgtagc ggtgagagta tccatcattt tacataagcg aagcattgtc
    13621 gaaggtagac aatcacagcg cttgtaaaat gatatttgcg aaggttctcg aaagtagaga
    13681 accacagaca aatcaaaaag cttcgggaag ggtgctcaat ttgaaattag cttggaatac
    13741 gcaaaaaaat aaaatgagcg atgttaaagg caaagagatg gaacaagaac gtaaagggag
    13801 aatcaaaaac gatgagattg atttgaaacg gacaaactta aactttgatt taattgaata
    13861 tgaacgtcat ttgtatcatc gtgtgaaaga tagagtcgat tattataaag aacaggggtc
    13921 acgtgtacag aaaaatagtg tggtgatgta ttccaatatc attacgttat cgaaagaaga
    13981 ggccgaccgt atgggagaaa cacgtacaaa acactacttt aaaacatgta aagattactt
    14041 cagtgaacgt tttggcgaag ccaatgtcgt ttcagcgaaa gtgcatatgg atgaatcagc
    14101 gcctcatatg caccttcact ttatacctgt gaatcatcaa gggcggttat cagcacgtac
    14161 agctatgaat cgacaagcca ttaatcacat ccatgatgaa ctaacaacac atctgtgcca
    14221 gcaaggtttt gatgttgaac gtgggagtac cgatgataat aaaacgtata ttcaagatat
    14281 tcatgaatac aaaaagaaag cgaaagtttt aagtgaattg gaccaacaaa ttgaaacgaa
    14341 aaaacaattg ttgagggata tcaacgattt acacgatgaa aaagaacatt taactcggga
    14401 tattcaaaac ttaaaacgga aaaatcattt tttacaagag gattctcaac aggctcaaga
    14461 agatatagac ctatacaagc aactgagaac gatttctagg gacgatttta aaaaagatga
    14521 ggaaaagtac caaaaagaaa tcaaagcgta tgaggcgtct ctgagcggcc ttagaatgaa
    14581 ttaccgagat ttgaacaagc gcaatcaaca tttaacaaca caaaataatc aactcgaaca
    14641 ccatttagac ctgttaaatg cacgtcatca agcgatgaac gacatggtaa gaaatgatac
    14701 acgtattttg tttgcgggac ttagatgtgc attgaaagat aggaacattg aattaagcgc
    14761 agaaattaaa tatcaacgta tgccagaagt cggtattgat cccgatacgg tggatcaggg
    14821 ggctttaaca catgcatatc aaggtgatgt gtcagggata gaccatcata taagaaaggc
    14881 atcagcacct attaaaaaag agacagagaa tgacttagaa ttagaataag tcaataaaaa
    14941 taagcactca ggcaagtatg atacttgttt gagcgcttat ctcaatgaaa agagtaagta
    15001 aaaacttaat aagctggcga cacttattaa gagcaataat aactttaatt actgaattag
    15061 tagactagtt cagtaattag gaacgatacc tttgtatttc tatattatta taagaattcc
    15121 aaggtagcaa agatattgta ttggaagtga taaatgtgag tatgattttt aaattaattg
    15181 atgaagatat tttgagtttc taaactttaa aaaatatctc cattctttta aaagtttatt
    15241 tttgtgttgg tttctttata aatattattt gaatgcgttt aaagtatttc actccgacct
    15301 ttttaatata tttttataaa tctttttaaa acctttttaa gtactgttta agacctagag
    15361 agacaaggct tttgaaatgt taaaggcata gttttgccac attaaaggca tagttttgcc
    15421 acattaaagg catagttttg ccacattaaa ggcatagttt tgccacatta aaggcatagt
    15481 ttttttattg ttatgccttt atctatatgt taccttaatt ataagggtta tgaggttttt
    15541 taaaaaatta caaaggcata gtttttttat tgttatgcct ttgtaaagag aggagtatca
    15601 tatgagtgga gaaactgtta tatataaaaa tgaaatgaac ttagtgcctt taagacgatt
    15661 tacagctact gaaatcaact tattttttgc aatgtgtaat aaattaaaag agcaagacac
    15721 taatacgtta cacttatcct ttgatgagct aaaagaatta agtaattata atccagaaac
    15781 gcgtaatata aacagatttg tagatgacct acaaagagtt tacgataaaa tgctagatat
    15841 tcgatatact attagaacag aaacaaaaat taaaaaattc gttctatttt ataaatatga
    15901 aattgatata tctgaaagat atttagaaat tgctacttcc ccagatttaa aatatatttt
    15961 aaactctatt actaataact ttactaaatt tgaattaaag gaaatgacac atcttaaatc
    16021 tacttatgcc aaaaatatgt ttagaatgct taaacaatat aagcattctg gttatatgaa
    16081 aattagggtt gaagatttta gagaacgttt agatattcca aattcttata gaatgtctaa
    16141 tattaatcaa tttgttctaa ctccaatcat aagagaacta tctacgatat ttaataatct
    16201 aaaaatcaat aaaatcaaag ctaaaaaagg acgtaaaatt gaatggctgg agtttatctt
    16261 tgacgctgag aaacgcattc acaataaacg acaacctcaa atgaccaatg taggtaaaca
    16321 gcgtcaatat atcaatcgtg agaaaacacc agaatggtta aatgaaggaa gattaggaca
    16381 atttcaagaa atacataatg aagatacaaa attaaaacaa gatcgagagg catttcaacg
    16441 tcaattagaa gaaaaatggg aggattaata atttaaatga gctacatgta tattttgctt
    16501 ttatttcctt taataatggg atttatcgta tcaataaaaa agaaaaaaca tgactaagga
    16561 gacataagaa ggtatgagta ataaatataa tatacatcca gcactatata taggaggatt
    16621 tgcggtattt tttagtttta tatttggatt tcctataggg acattaatgg gtctaggtat
    16681 agggatagga gttagtaaaa aaaagaaatg attacagttt tactcacata aaatttgtaa
    16741 aagagtttac agatgaagaa gttacacgat atactgtaat taacaaattg taggtgtaca
    16801 tcactgtacg caaagacccc cacgtagctt gccggctgtg ggggtctttt ttactatcgt
    16861 tgtttcaaac tatcataaaa atagtttgcc ataatactaa tgatgagtgg atcaacgata
    16921 tttaagataa caaattgtag gatatccaac actatacgca cacctccttt ctgcacagga
    16981 agtgcgttct aattataata tacaagtttt ttcaatgcat tacttaaaga gtggaatgcc
    17041 tttactaaaa caataaatag atttgtaaaa gagagtggca ttagtgaata aagaagaata
    17101 tttaaagatt attcaaaaag aaacaaaaaa gataaatact gatgaaaaag aagatatttt
    17161 atctaaatac gagtcttatt ttattaatgg atataaaaac aataaaaatg atgaggaaat
    17221 tattaaagaa cttggtgatc ctgtaaaaat agccaaagaa ataaatgctg taaattcatt
    17281 atataaagta gaaaataaaa aaagtgttaa aagtatattt tctgcagcct tttctattat
    17341 ggagcttagt attttaaact taattttaat aatctccata ttttatacaa tgactcaggt
    17401 tcataataat cataaagttt ctggagaaac tattttaact ctttcaacat ggctatttgc
    17461 attttgggga gttatgatta ttactagttt tttagtcaga gatttttctc aaggtacgtc
    17521 acagttgtat ttgaatagtt ctaaaaatag agtgaagtac tttatatctc aactgatatc
    17581 catattaatt gctagtgtca tagtattttt aacattatac gtattcgttt tgataatgca
    17641 gaacatagga gacggtgaac ctttaaaaaa tgaagtagtg ggaaaagctt taggaatata
    17701 tatcctatta tttttatttt atggtctatt tctatttcta attactttat tagtaaaaag
    17761 ttcttcttta gtattttcaa ttggggtttt tcttatatta atcataccta tagcaactaa
    17821 tttagttcca ttaattccag aatatggtga tgaagttaga aaagccttga aatatatacc
    17881 ttttaacttt ttaatcaata atgtttggct tggatctctc aaattaaatg gatggcaaac
    17941 atttatttca atagcttcag taatactatt agctataatt gacttcttca ccatttctaa
    18001 aagagattat taaagattaa caaaaccaat gtttttccta acagactgat taagagcgat
    18061 tagcatagtt gctagtcgct cattttattg ttgttctttc aatcgcttaa tcgcattttt
    18121 taaggatctt tattattaag actaaaccat aatatatatt attatgaatt ttaaaatgat
    18181 ataacgctct tataaaagat gctattacaa taaaattgta tgattatcaa taaaaaaacg
    18241 atgtctaaac ggaataatta cttttctcgt atcctgttct ttaagtttat tgtataatgg
    18301 aaagaataaa tctacttcag tacttgtaaa acgtcttaat ggtactaaac ttatttatat
    18361 atactactgt tttaccagac ataaaaaact cctctccaaa tatataggtg atgcaagata
    18421 caaaacatct cttttaacgt ctcaaacctc tttttgcttt aaagctgaga tagtgtctaa
    18481 aaaatttata aaaagatatt aaaaattttt gggctttagc ccttcacaaa ttcaaaaaaa
    18541 caaaaaggaa agagtccaga gattttatgt tccggactct tcaattctaa aatatttagt
    18601 ttagtaaaga atatagttac tagtaattgt actaggttat aagttaatgt taaatagttt
    18661 cggtatcaat aatttttatt aaagaccaat acgttttaag aatccaataa attcttcata
    18721 gatatcttct aacataaatt tccctccttg atattacaaa taagtaatat acttagcaat
    18781 aattattttg tgtaaggttt gtcttggcca taatattcga ttttatcata gaagaattga
    18841 ccaaaaattg ttaagaagcg atgtaacatg taatggcacc tccctattta ctataataca
    18901 tatttagtat aaccctattt tcaaatcata aaacatttat ttacaattat aagtgaaatg
    18961 tttcttaatt aagtttaaaa atgaacagaa taacgctttt tgtaatagat aatattttcg
    19021 cttaataaga gtatacctat tatgaacgaa gttattggta acccattatt agataaattt
    19081 atgaaaaatc taatcattca aatattagca atggtttcag aacaagaaag aaatgaaagt
    19141 aagcgcagac aagcacaagg cattaaagct gttaaagaaa aaggtgtata taaaggacgc
    19201 ccattattgt attctgcaga tgcaaaagat ccacaaaaac ccattatcta tcatcgagtt
    19261 gtagaaatgt tagaacaagt caatacaatt ggtaaagaag tcaatatcac aagacacacg
    19321 gttcatagga ttaaacagaa taaaaacata taaatgtgtt ctatttcaat caaagagaaa
    19381 aagtgagtga caatctagta tatacagaag ttttcctaca cgctgataag atagtataga
    19441 ggatgcactc tattctttga tctagttgat aactataata gagaaaattg gaaaagtata
    19501 attggaagta aagttattga taatcatata aaacactaaa ttgacttctc ataatcacag
    19561 acaaataata agaatttggc tttaatatgt ttaaagtttt ttaataaggt taaacaaagt
    19621 atgtgagaca aaaaataagg aagtataatt ttaagcgatg aatgataaaa aagctaagtt
    19681 ataaagctag cttgagatat tgttgacgat tatataatta gttcattcga atatctattt
    19741 aattttacaa atctcttcat gcaagatata ctgaaattaa caaatattga actcatgtat
    19801 caccgaaccc caacctatgc cagtaggttg gggttcttta gtggtgaggc tatgtcgcct
    19861 tatttattgc ggttgtttag ccaaaacgtg aaaatcgcaa cacagcactc tactataata
    19921 ggtgctatta tacaaacaaa tattaaactc atgatttcac ctccttccgc cgaatctatc
    19981 gccggaagta agacgaccta agtattataa cagaaactta attaatatac ttctttggta
    20041 ttattcttta tataacaaat aaaataaatg aaaaatttca gataactaat caaataaata
    20101 aatttaaacc gctgttttgt catttgagat tttgaataaa gatacaaaat gctcacaaat
    20161 gaaaaagaat gaaaacgcgt cgttaaaggg atgtataaaa gttgtataaa gggaaatgat
    20221 gacaaatagg gacaaatgcc gaaatgacgg cgtttgtccc ttgattgtaa gttaacataa
    20281 ttaactatta taggtagtta gtttgtatag tttatgcatc ttctaactag ttatcggtga
    20341 ctattacatc ataagttaga agctacttaa tataataaaa gcaagtgatt cacaaaattg
    20401 taaatcactt gcttttatac tgttctttta atcgtttaat cgcatttttt agtggccgat
    20461 catcgcgata tgtattgaag tttaaaaatg ctgtactatc aaaatgttgt aataagtgat
    20521 gaaagacgtc attttcttgt ctcagttggt cgatttcatc ttccaactga tgaatatgat
    20581 gctggagtgc ctgattattc gatttgagtg cctcgttgtc ttttttaaac aattcactga
    20641 cttcactgga ttctttaatt tgttcgatga ctgtcggttt aatgcgatta ccaatggctg
    20701 tatgacgtat gtattcggtc acattcatct ctcgaatatc cgcaagtgca caaatctttt
    20761 cgtattgcga ttgacttaca cgaattgtta agattttttc ttttgaattt tgtttttttg
    20821 gcattgaatc acctcataat taatatatga taagcataca tatgtgtgct tatctttata
    20881 ttaatataac atacatatgt atgttaataa atatgtatga ttcgaggtgt tgtgagctaa
    20941 catttggcat acatattatc aaacatattt gtttgataat gcgtatgtca tttgttagct
    21001 atagaacgga attcaaaaat atatttttga atgtagtgat ggcctcgcca gagcgaagat
    21061 aactcttaca tttgaatgta agagtatatc gagctatact ctcattgcgg aatcagcctc
    21121 acatgtttga ggcgtagcgg tgagagtatc catcatttta cataagcgaa gcattgtcga
    21181 aggtagacaa tcacagcgct tgtaaaatga tatttgcgaa ggttctcgaa agtagagaac
    21241 cacagacaaa tcaaaaagct tcgggaaggg tgctcaattt gaaattagct tggaatacgc
    21301 aaaaaaataa aatgagcgat gttaaaggca aagagatgga acaagaacgt aaagggagaa
    21361 tcaaaaacga tgagattgat ttgaaacgga caaacttaaa ctttgattta attgaatatg
    21421 aacgtcattt gtatcatcgt gtgaaagata gagtcgatta ttataaagaa caggggtcac
    21481 gtgtacagaa aaatagtgtg gtgatgtatt ccaatatcat tacgttatcg aaagaagagg
    21541 ccgaccgtat gggagaaaca cgtacaaaac actactttaa aacatgtaaa gattacttca
    21601 gtgaacgttt tggcgaagcc aatgtcgttt cagcgaaagt gcatatggat gaatcagcgc
    21661 ctcatatgca ccttcacttt atacctgtga atcatcaagg gcggttatca gcacgtacag
    21721 ctatgaatcg acaagccatt aatcacatcc atgatgaact aacaacacat ctgtgccagc
    21781 aaggttttga tgttgaacgt gggagtaccg atgataataa aacgtatatt caagatattc
    21841 atgaatacaa aaagaaagcg aaagttttaa gtgaattgga ccaacaaatt gaaacgaaaa
    21901 aacaattgtt gagggatatc aacgatttac acgatgaaaa agaacattta actcgggata
    21961 ttcaaaactt aaaacgga
//
