LOCUS       NZ_CP043055             9203 bp    DNA     circular CON 09-JAN-2024
DEFINITION  Acinetobacter pittii strain AP43 plasmid pAP43-3, complete sequence.
ACCESSION   NZ_CP043055
VERSION     NZ_CP043055.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN12612836
            Assembly: GCF_008121475.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter pittii
  ORGANISM  Acinetobacter pittii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 9203)
  AUTHORS   Ruan,Z. and Jia,H.
  TITLE     Genomic Epidemiological Investigation of Acinetobacter pittii
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9203)
  AUTHORS   Ruan,Z. and Jia,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-AUG-2019) Department of Clinical Laboratory, Sir Run
            Run Shaw Hospital, School of Medicine, Zhejiang University, 3
            Qingchun East Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Oxford Nanopore GridION; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/09/2024 03:14:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,146
            CDSs (total)                      :: 4,050
            Genes (coding)                    :: 3,922
            CDSs (with protein)               :: 3,922
            Genes (RNA)                       :: 96
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 71 of 128
            Pseudo Genes (internal stop)      :: 28 of 128
            Pseudo Genes (multiple problems)  :: 17 of 128
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP043055.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9203
                     /organism="Acinetobacter pittii"
                     /mol_type="genomic DNA"
                     /strain="AP43"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:48296"
                     /plasmid="pAP43-3"
                     /geo_loc_name="China: Hangzhou"
                     /collection_date="2018-05-21"
                     /collected_by="Huiqiong Jia"
     gene            1..924
                     /gene="repM"
                     /locus_tag="FXO17_RS20785"
                     /old_locus_tag="FXO17_20785"
     CDS             1..924
                     /gene="repM"
                     /locus_tag="FXO17_RS20785"
                     /old_locus_tag="FXO17_20785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004282204.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_000845851.1"
                     /translation="MKTELIVKDNALINASYNLDLVEQRLILLAIVEARESGKGINAND
                     PLTVHAESYINQFGVHRNTAYQALKDACDDLFARQFSYQSLSEKGNIINHKSRWVSEVA
                     YIDNEAVVRLIFAPAIVPLITRLEEQFTKYEIQQISNLTSAYAVRLYEILIAWRSTGKT
                     PLITLSDFRQKIGVLDTEYKRMYDFKKYVLDIALKQVNEHTDITVKVEQHKTGRSITGF
                     SFSFKQKKSVTKSAKSIGVSEDITITLTDAQRYSFASKLSELPEMGKLSQGTESYEQFA
                     VRIADMLKQPEKLKELTPLLRKVGFQ"
                     /name="repM"
     gene            992..1537
                     /locus_tag="FXO17_RS20790"
                     /old_locus_tag="FXO17_20790"
     CDS             992..1537
                     /locus_tag="FXO17_RS20790"
                     /old_locus_tag="FXO17_20790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_000736775.1"
                     /translation="MKKLSVSELAKLYGYSRQAIYAHINKGNLSKGSDGLIDFAEAIRV
                     FGEPQKKDTNVNQSQSINSQNLTEVDLLKRQVDILEKQLNQALFRENQSLERESFYQDQ
                     IEAMQRLLEAPKANMTTFTDQEQSQANVAQVQPEPNIDDPKHDGLTTPENKRIPVPEHV
                     EPEPKKRGFWSRFFLPYG"
                     /name="plasmid replication DNA-binding protein"
     gene            complement(1757..2608)
                     /locus_tag="FXO17_RS20795"
                     /old_locus_tag="FXO17_20795"
     CDS             complement(1757..2608)
                     /locus_tag="FXO17_RS20795"
                     /old_locus_tag="FXO17_20795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="WP_002115246.1"
                     /translation="MSKIIACIDGSLATNTVCDYAAWFSDKLNSPLQLLHVIDKPKAKA
                     PQDLSGAIGLGSRETLLNELVELEERKGKIELEHGQILLREAKNYLLEKFSIDAQSFQR
                     HGSLLETIMGMEEDIRVLVMGKHGTETEHNSSKVGTHIENVVRALHKPVLITSSPFSPP
                     QSFLIAFDGSPTARICVDKIANSPLLKTLTAHVVYVGKPNSDMTSQVTWAKELLANNGF
                     DVIDSVLEGDVEKSILDYQEKNVIDMIVIGAYGHSKIRQFFIGSTTTKLLSSSTKPVLL
                     LR"
                     /name="universal stress protein"
     gene            complement(2621..4108)
                     /locus_tag="FXO17_RS20800"
                     /old_locus_tag="FXO17_20800"
     CDS             complement(2621..4108)
                     /locus_tag="FXO17_RS20800"
                     /old_locus_tag="FXO17_20800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953322.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="WP_002115244.1"
                     /translation="MLSTIREQWFSNIRGDVLAGIVVALALIPEAIAFSIIAGVDPKVG
                     LYASFCIAVVISFVGGRPGMISAATGAMALLMVTLVKEHGLQYLLAATILTGFIQILAG
                     YLKLGALMRFVSKSVVIGFVNALAILIFMAQLPELTNVTWHVYAMTIGGLAIIYLFPYI
                     PVIGKLLPSPLICIVLLTLFALFIGLDVRTVGDMGQLPDTLPIFLLPDIPLNLETLAII
                     LPYSLGLAAVGLLESMMTATIVDDLTDTNSDKNRECKGQGVANIASGFLGGMAGCAMIG
                     QSIINVKSGGRTRLSTFSAGVFLLIMVVFISDWLKVIPMAALVAVMIMVSIGTFNWDSL
                     RNIRQYPLSSNIVMIVTVIVVVATHNLAYGVLVGVLLSALFFANKIERYMAIQSEFNEP
                     ENTRIYTVTGQVFFSSSDKFTSAFDFKEALSKVVIDVSQAHFWDVSAVAAVDKVVIKFR
                     REGTEVELIGMNEASKTLVDKFGIHDKPDALDRLNSH"
                     /name="SulP family inorganic anion transporter"
     gene            complement(4497..5009)
                     /locus_tag="FXO17_RS20805"
                     /old_locus_tag="FXO17_20805"
     CDS             complement(4497..5009)
                     /locus_tag="FXO17_RS20805"
                     /old_locus_tag="FXO17_20805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_001089574.1"
                     /translation="MNSVHEIIEKIHNEWEIEPKKAIQRGRECPFPLQCSLNLKSKIYP
                     QIPQVLLPKVLEDFYTVSNGADLFKDQEYGQWGLKLYSIEEVIFASKIYKSNRNNDALQ
                     SDLIIGEFYGDSDLLLVRCDPNSDDYGSIFVVLPIDQRQDWYIVANTFQEFISKFYETQ
                     GDKFWEP"
                     /name="SMI1/KNR4 family protein"
     gene            complement(5048..5566)
                     /locus_tag="FXO17_RS20810"
                     /old_locus_tag="FXO17_20810"
     CDS             complement(5048..5566)
                     /locus_tag="FXO17_RS20810"
                     /old_locus_tag="FXO17_20810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447193.1"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_000447195.1"
                     /translation="METFAEPVFSNDLLAKAESGDTSAQLELAEIYLYGHGVDSDENQA
                     EIWAIKSAENGNVAAMFWLADGYVTYARLIEDDDKNDSLEHFQKAFKWFQKASENGHSE
                     SMVELADLYTRADSGIEVNIKKALELREKAAKLGNKKAMRSLSAMYRDGIGIPKNTDLA
                     QSWWDKSEN"
                     /name="tetratricopeptide repeat protein"
     gene            complement(5741..5950)
                     /locus_tag="FXO17_RS20815"
                     /old_locus_tag="FXO17_20815"
     CDS             complement(5741..5950)
                     /locus_tag="FXO17_RS20815"
                     /old_locus_tag="FXO17_20815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000069475.1"
                     /translation="MSNNKPLKNSTKLLVNLDKFIFLVNAADSLEEIEIIRDLCCEYFS
                     HCKRPSYYIDIFDNAYWLKYYEIA"
                     /name="hypothetical protein"
     gene            complement(5943..6245)
                     /locus_tag="FXO17_RS20820"
                     /old_locus_tag="FXO17_20820"
     CDS             complement(5943..6245)
                     /locus_tag="FXO17_RS20820"
                     /old_locus_tag="FXO17_20820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001129974.1"
                     /translation="MAKSLQELLASRSPESQARIQKMADELLLESQLHLIREELEISQK
                     ELAATLGIKQPSLSAIENRGHDLKISTMKKYVEAMGGKLRIDVELPTGKHIGFNV"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(6238..6594)
                     /locus_tag="FXO17_RS20825"
                     /old_locus_tag="FXO17_20825"
     CDS             complement(6238..6594)
                     /locus_tag="FXO17_RS20825"
                     /old_locus_tag="FXO17_20825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005194067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000269904.1"
                     /translation="MWTVITTDLFNEWLEQQDEATQEKVLAALVVLQQQGPSLGRPLVD
                     TVYDSKFTNMKELRVQHRGKPLRAFFAFDPLRQAIVLCIGDKSNKKRFYTEMLAIADEQ
                     YALHLSTLGDQSNG"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(7122..7439)
                     /locus_tag="FXO17_RS20830"
                     /old_locus_tag="FXO17_20830"
     CDS             complement(7122..7439)
                     /locus_tag="FXO17_RS20830"
                     /old_locus_tag="FXO17_20830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005065053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000900860.1"
                     /translation="MLGKNHHFLKKFSISDAAIAYKKPRSTILKYIKSGDFELDYNKLI
                     EYSQLVRKFGELTYPIQDEREQQIKKLKDEVMHLKKQLNFFKYTSISNKNRLLISHKHS
                     I"
                     /name="hypothetical protein"
     gene            complement(7644..7835)
                     /locus_tag="FXO17_RS20835"
                     /old_locus_tag="FXO17_20835"
     CDS             complement(7644..7835)
                     /locus_tag="FXO17_RS20835"
                     /old_locus_tag="FXO17_20835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004706315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000102616.1"
                     /translation="MSTELVNSANIISFPKPCAFCESTEHVQLFAGLMLCRSCQENIKI
                     TNPDLFATNDQIQQKAQD"
                     /name="hypothetical protein"
     Typing          2..605
                     /name="rep_cluster_1254"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.835"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaaaacag aactaatagt taaagataat gcattaatta atgccagtta taaccttgat
       61 ctagtcgagc aacggttaat tcttctagct atcgttgaag caagggaatc gggtaaggga
      121 ataaatgcta atgatccatt aacagttcat gctgaaagct acatcaatca atttggtgta
      181 catcgaaaca cggcttatca ggcattaaaa gatgcttgtg atgatctatt tgcaagacaa
      241 ttcagttatc aaagtcttag tgaaaaaggc aacattatta atcacaagtc aagatgggtg
      301 agtgaagtcg cttatattga taatgaagcg gttgttagac ttatttttgc tcccgctatc
      361 gtgcctttaa ttacaagact agaagaacaa tttacaaagt atgaaataca acaaataagc
      421 aatttaacaa gtgcttatgc cgttcggtta tatgagatat tgattgcatg gcgtagtaca
      481 ggaaaaacgc ctcttataac tttgtctgat ttcagacaaa aaataggtgt actcgatact
      541 gaatacaaac gaatgtatga ctttaaaaaa tatgtcttag acattgcatt aaagcaagta
      601 aatgaacata ccgacattac tgttaaagtt gaacagcata agactggtag atcaattaca
      661 ggtttttcat ttagctttaa acaaaaaaaa tcagtgacga agtcagctaa aagtataggt
      721 gtaagcgaag atataacgat cactttaaca gatgcacaac gctattcatt tgcgagtaaa
      781 ttgtcagagc ttccagaaat gggaaaactt tcacaaggca ccgaaagcta tgaacaattt
      841 gctgtacgga ttgcagatat gctaaaacag ccggagaaat taaaagaact tactccatta
      901 cttcgaaaag ttggctttca ataaatgatg tcaattgaca ttgtaaagtt gacagtcaag
      961 tattaacaca aattgaaaac tggtttacat aatgaaaaaa ctgtcagttt cagagttggc
     1021 taagctttac ggatattcac gacaagccat atatgcccat ataaacaaag gaaatttatc
     1081 taaaggatct gatggattaa ttgacttcgc agaagccata agagtttttg gggaaccaca
     1141 aaagaaagat actaatgtca atcaaagtca atcaattaac agtcaaaact tgacagaagt
     1201 tgacctatta aaacgtcaag ttgacatact ggaaaaacag ttaaatcaag cactgtttag
     1261 agaaaatcaa tcactagaac gtgaatcgtt ttatcaagat cagatcgagg ccatgcagcg
     1321 cttactagaa gcaccaaaag ccaatatgac tacgtttacc gatcaagaac agtcgcaagc
     1381 gaatgtagct caagtacagc cagaacctaa tattgatgat cctaaacatg acggattgac
     1441 tactccagag aataagcgca ttcctgttcc agagcatgtt gaaccagagc ctaaaaagcg
     1501 tggcttctgg agtcgttttt ttcttccata tggttaactt aggctaaata aaaccgtgga
     1561 acattgctca ataaataagc gtggaacgtg aaaaatcata aaaaaaaccc accttgggga
     1621 agatgggcta taaactagaa actacagcat tgatttctaa ggaaaattat aacacatttc
     1681 gtataaggtg tattatgtta attttagaaa ttctaaaaaa gggatagttt ttaactatcc
     1741 ctttatcttg taaaaattat cttagtaata atactggttt tgtagaactt gataacaatt
     1801 tggtcgtcgt actaccaata aaaaactggc gtatctttga atgaccatat gcaccaatca
     1861 caatcatatc aataacgttt ttttcttgat aatccaatat agatttctca acatcacctt
     1921 caagcacact atcaatgaca tcaaaaccat tatttgcaag tagctctttt gcccaagtga
     1981 cttgtgatgt catatcacta tttggcttac caacatatac cacatgagct gtcagggttt
     2041 ttaataaagg gctatttgca attttgtcta cacaaatacg tgcagtagga cttccatcaa
     2101 aagcaattaa aaatgactga ggtggactaa acggtgagga tgtgattaac acgggtttat
     2161 gaagagcacg aacaacattt tcaatatggg ttccaacttt actggaattg tgctcggttt
     2221 cagttccatg cttacccata acaagaactc gaatatcctc ttccattccc atgattgttt
     2281 ctaaaagact gccatggcgt tgaaagcttt gagcatcaat agagaacttc tccaatagat
     2341 agttttttgc ttcccgaaga agaatttggc catgctctag ctcaattttc cccttacgtt
     2401 cttccagttc aaccaactcg tttagcaagg tttctcgact tcctagacca attgcaccac
     2461 ttaaatcttg tggtgctttc gcttttggct tatcaatgac atgcaataac tgaagaggtg
     2521 aattcaattt atcgctaaac caagctgcat aatcacaaac ggtatttgtt gctaatgatc
     2581 catcaataca tgcaataatt tttgacataa ttcatccctc ttagtggcta tttaagcgat
     2641 ctaaagcatc tggcttatca tggataccaa acttatcgac taacgtttta ctggcttcat
     2701 tcattccaat cagttcgact tctgttcctt cacgtctaaa cttaatgacc actttatcta
     2761 cggcagcgac cgcagacaca tcccagaagt gagcctgact aacatcaatc acaacttttg
     2821 aaagtgcttc tttgaaatca aatgcagaag taaatttatc tgatgagctg aagaacactt
     2881 gacctgttac cgtataaata cgggtatttt caggttcatt aaattcagac tgaattgcca
     2941 tgtagcgttc aattttattg gcaaaaaata atgcagaaag aagtacacca actaatacgc
     3001 cataagccaa gttatgtgtc gcaacgacca cgatgactgt aacgatcatc acaatattgc
     3061 tagatagggg atattggcga atattgcgta gtgaatccca gttaaatgtt ccgattgaaa
     3121 ccatgatcat tacggcaacc agtgcagcca ttggaatgac tttgagccag tcactgataa
     3181 acaccaccat aattaacagg aagacccccg cactaaaggt agataaacgg gtacgaccac
     3241 cagatttcac attaataatt gattgaccga tcatggcaca gcctgccatt ccgcctaaaa
     3301 agcctgaagc aatattggca acgccttgtc ctttacactc acggttttta tcactattgg
     3361 tatctgttaa atcgtcaaca atcgttgctg tcatcataga ttcaagcaaa cccacggcag
     3421 ccaagcctag tgaatagggc aaaataatcg ctaaggtttc aagatttaaa gggatatcag
     3481 gaagcaagaa aattggaaga gtatctggta attgtcccat atcaccgacg gttcttacat
     3541 ctaaaccaat gaacaaggca aagagcgtga ggagtacaat acagatgagg ggagagggta
     3601 aaagcttgcc tattactggg atatagggga atagataaat aatggctaaa ccaccaattg
     3661 tcatcgcata gacatgccat gtcacattgg tgagttcagg caattgggcc ataaaaatta
     3721 gaatagccaa ggcattcaca aagccaatca caaccgactt tgacacaaag cgcatcaatg
     3781 cacctaattt tagatagcct gctaggattt gaataaatcc tgtcaaaatt gtggctgcta
     3841 ataagtattg cagaccatgc tctttaacca gtgtgaccat taataaagcc atagcaccag
     3901 ttgcagcaga aatcatccct ggacgaccgc ctacgaaaga aatcaccacg gcaatacaga
     3961 atgaagcata taaccctacc ttagggtcga cacctgcaat aattgaaaag gcaattgctt
     4021 caggaattag agccaaagca acaacaatac ccgcaagaac atccccgcga atattggaga
     4081 accattgttc tcgaatagtg gataacatga aaatagccta ttttttttaa attttaggaa
     4141 aggctagtga tgtgatatat gacacacaag ctactacacc acatcactag acagtgatga
     4201 gttatttact gttttaagag ataaataaac ttatggtggc gtaagtgtca tattaagaaa
     4261 gatatctatt ttggagggtt tcgggggcaa tgatagcagt taggcccttt tctatccacc
     4321 ctaaccgcag tactgaagta aaagtaagaa tgatcataga taattttaga attgatttat
     4381 gtccatttaa cataatgggc gttatatgaa attcaaaaaa tgatactatt tttgtgataa
     4441 ttaaataaat tttaggtgaa cataagttaa atagagctta tatcggccat ataattttaa
     4501 ggttcccaga atttatcacc ctgagtttca taaaatttac taatgaattc ttgaaaagta
     4561 ttagcaacaa tgtaccaatc ttgtctttga tctataggta agacaacaaa aatagagccg
     4621 taatcatcac tattaggatc acatcgaact aacaataagt ctgaatctcc atagaattct
     4681 ccaataatta agtcactttg aagagcgtca ttattacgat tacttttata aatttttgaa
     4741 gcaaaaatta cttcctcaat agaatataat tttaagcccc attgtccgta ttcttgatct
     4801 ttaaatagat ctgcaccatt agatactgta taaaaatcct ctaatacttt tggtaaaagt
     4861 acttggggta tttgtgggta aattttgctt tttaggttta atgaacactg caaaggaaag
     4921 ggacattccc tacctctctg aatagctttc ttaggttcaa tctcccattc attatgtatt
     4981 ttttctataa tttcatgaac actattcatt tattagactc ttaaaaaatc cttaactttt
     5041 actaaaatta attttcagac ttatcccacc aactttgagc taaatcagta tttttaggaa
     5101 tgcctatacc atcacgatac atagcggaaa gacttcgcat tgctttctta ttacctaact
     5161 ttgcagcctt ttcacgaagt tctaaagctt tcttaatatt aacttctatt ccgctatctg
     5221 cgcgagtata taggtcagct aactcaacca ttgattcaga atgaccattt tctgaagctt
     5281 tctgaaacca cttaaaagct ttttggaaat gttctaaaga atcgtttttg tcatcatcct
     5341 ctattaatct agcataggta acatatccat cagctaacca aaacattgct gctacatttc
     5401 cattttcagc tgatttaata gcccaaattt cagcttgatt ttcatctgaa tcaacaccat
     5461 gaccatatag ataaatctca gctaattcta actgggcaga agtatctcca ctttctgctt
     5521 tcgctaataa atcattagaa aaaacaggtt ctgcaaatgt ttccattgaa aggcaaactc
     5581 ctaaagccat aaaaatattt actaatttat tcaattctta acctttaaat taaactctta
     5641 ggcttgtatg tttttacatc atacctaaaa gaaaactcta aaattagagt atatttttag
     5701 tcctatttaa catagaaact cttatgcgaa tctagaagga ttaagctatt tcgtaatatt
     5761 ttaaccaata agcattgtca aaaatatcaa tgtaatagct tggcctctta caatgtgaaa
     5821 aatattcaca gcataaatct ctaataattt caatttcttc taggctatcg gcagcattga
     5881 ctaaaaatat aaatttgtct aagttaacaa gtaatttagt actatttttc aaaggtttat
     5941 tattagacat tgaaccctat gtgttttcct gttggaagct ctacatcaat acgaagtttt
     6001 ccacccattg cttcaacata ctttttcatc gttgaaattt taagatcatg accacgattt
     6061 tcgattgctg ataatgacgg ctgtttaatt ccaagggttg cagctagttc tttctgggaa
     6121 atttctaact cttctcggat aaggtgaagc tgactttcta aaagtaattc atcagccatt
     6181 ttttgaatac gagcttgact ctctggagag cgactagcca ataattcttg taagctctta
     6241 gccattagat tgatctccta aagttgagag atgaagtgcg tattgctcat ctgcaattgc
     6301 tagcatctct gtataaaaac gctttttatt actcttatca ccaatacaca gcacaatcgc
     6361 ttgtcttagg ggatcgaatg caaaaaatgc ccttaacggt ttaccacgat gctgaacacg
     6421 tagttccttc atattggtaa atttagaatc gtagacggta tctactaaag gacgacctaa
     6481 actaggccct tgctgttgta gaacaaccaa tgcagctaag actttctctt gtgttgcttc
     6541 atcttgctgt tcaagccatt cattaaacag atccgttgta atgactgtcc acatattaca
     6601 atcacaatat agattacagt ctatatatta aatctgattg aatgactttg caaatggcaa
     6661 taaaaaatcc cgacgtcatg tcgggatttt tcggtatgga gcgcataggt agggctgact
     6721 acctgatggt catggtgcct gactgattat tattgttgtt ttaagtcatt gaacatcctg
     6781 tccatataga tcgatcataa gagcttcatc gggggataga tacagacaat ttcgtgaaac
     6841 gctgtaagcc aaaacgtaca aaaaataatc aaaatttatc ccaatggtta tccgcataaa
     6901 ttgtggattc ttttgggtaa aaaaggctta caaactctat ggaattggta tttttgatca
     6961 ttttttaacc aattttattg gcaagaagta tcagaattga acataaaaaa accgatttat
     7021 ttctaaatcg gttgaacgag atcgttccag gggtttaact caatgtaagt tgttgatctt
     7081 aaagtaaact taaagggcca tttcggataa cgcccattat gttaaatgga atgtttatga
     7141 gaaattaata gtctattttt gtttgagatt gaagtatatt taaaaaagtt aagttgtttt
     7201 tttaaatgca taacttcatc ttttagtttt ttgatttgtt gctctctttc gtcctgtata
     7261 gggtaagtaa gttcaccaaa ttttctaact aactgactgt attcaatcaa tttattgtag
     7321 tcaagttcga aatctccgct ttttatatat ttaagtatag tcgagcgagg ttttttatac
     7381 gctatagcag catcactgat cgaaaatttt tttaaaaaat gatgattttt acctagcata
     7441 ctatttcact taaggcatta ttaatttcat atatatatgt taataaaatt aacacataca
     7501 agatataaat ctttaatcat tattggttaa taatcgaacg tttactttac acatgcccta
     7561 ctctgataat ttttctatta ttaaatcaat atgcttttaa aaatttatat tattaacata
     7621 atacacctta tacgaagccc aggttaatcc tgggcttttt gttgaatctg atcattggta
     7681 gcaaacagat caggattggt aattttgatg ttttcctgac aactcctgca aagcatcagc
     7741 ccagcaaaaa gttgtacatg ttccgttgat tcacagaagg cacatggctt aggaaaagag
     7801 atgatattgg ctgaattgac taattctgtt gacataagaa gtaaccttgg attgtacata
     7861 tttattttta ataaatttca atactttata cctaatttag ccactaaaat ttgtacatta
     7921 ttgtataatc catgtgtaca tattattttt tataattttc attcacttag acccaaaata
     7981 gtatttattt ttgtacaaca ccatgtacag aacaataatc atataaatca aatttttagc
     8041 ataaaaaagt ccattaattt tgtacacaat tctgaaactt aaaaatctaa actttcatca
     8101 atttttttca taatttcaat aaattaacct taattttaag atatattctg aaatttggtt
     8161 tgaaagttgt ttttacatta tatttcaata ctttaaatca aaaaattgga ttttttttga
     8221 aaaactcaat gaaagtttat tttttattta aaaacaacta gttatattag tttttatcca
     8281 tttttttgaa acagtttcta tatgataaaa aaacctataa aaaccatatc tagcaaaggt
     8341 ttgagggtta tcatctttag atgcgtggtg tgtgacaaaa aaatcccggc atgtgccgga
     8401 ttctggatta gaaaattggc taaagtgacg taggactggt gcttggtttt acatggaaaa
     8461 aagtatttat tttctggttt ataaaaacgt aaaaagatca gtttttgttc attcatccag
     8521 gttaaaaatt tcaacctaaa actttaatta tgaaaagctt cacagaaagc attcaaatgc
     8581 gatttaagag cctttatcta aaaaacatag atcttatagc gaaaaacaga aaacagctca
     8641 aaaaacgcaa aagagagtga agtaaagaga tgttttgact ttagatagct gcatagagcg
     8701 agtgtctacg agcgaactat caaaatttgc gtctagactc tctgaaaaac atttttttgc
     8761 cctctttagc ctaagaaagc ttaattttca tgcagaaatt tgctcctgga ccgagcgtag
     8821 cgagaaaaaa agctcatgag cgaagcgaat tccgagttgc ttttgctttt tcttaaagtc
     8881 acgcaagtat taaccaaaaa attgccccga cgaactgagc gaaagcgaag ttcaatagag
     8941 tttgagcgaa gcgaaaacca agggcaattt ttcatgacct gagcttttaa atatttttaa
     9001 atcttttaaa tgcttttaga catgctgaaa gcctttattt ataaaattct tagagactat
     9061 aaaacgaggt ttaccttgca ttaaaacgag gtttaccttg cattaaaacg aggtttacct
     9121 tgcattaaaa cgaggtttac cttgcattaa gcgagtttat gatatagcct cgtcttattg
     9181 aattaaaaat ataacctttt cat
//
