LOCUS       NZ_CP040621            27068 bp    DNA     circular CON 25-JUL-2023
DEFINITION  Staphylococcus aureus strain J01 plasmid pJ01-02, complete sequence.
ACCESSION   NZ_CP040621
VERSION     NZ_CP040621.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN11823229
            Assembly: GCF_005889995.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27068)
  AUTHORS   Miller,C.R., Dey,S., Smolenski,P.D., Kulkarni,P.S., Baines,S.L. and
            Berti,A.D.
  TITLE     Suppression of daptomycin resistance development in Staphylococcus
            aureus is a class effect of beta lactams and is independent of
            daptomycin-beta lactam synergy
  JOURNAL   Antimicrob. Agents Chemother. (2019) In press
REFERENCE   2  (bases 1 to 27068)
  AUTHORS   Berti,A.D., Baines,S.L. and Gurdziel,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2019) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: Unicycler v. v0.4.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 842.0x
            Sequencing Technology             :: PacBio; MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/25/2023 04:18:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,968
            CDSs (total)                      :: 2,887
            Genes (coding)                    :: 2,804
            CDSs (with protein)               :: 2,804
            Genes (RNA)                       :: 81
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 44 of 83
            Pseudo Genes (incomplete)         :: 42 of 83
            Pseudo Genes (internal stop)      :: 15 of 83
            Pseudo Genes (multiple problems)  :: 17 of 83
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040621.1.
            Bacteria and source DNA available from BEI Resources
            (BioRepository) or Andrew Berti (PI).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27068
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="J01"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pJ01-02"
                     /geo_loc_name="USA: California"
                     /lat_lon="32.72 N 117.16 W"
                     /collection_date="2011"
                     /collected_by="Sakoulas"
                     /genotype="ST8-MRSA-IVg CC8 spa t064. PFGE type USA300. agr
                     type 1."
                     /note="clinical sample"
     gene            426..1169
                     /locus_tag="FF957_RS15055"
                     /old_locus_tag="FF957_15055"
     CDS             426..1169
                     /locus_tag="FF957_RS15055"
                     /old_locus_tag="FF957_15055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(1396..1581)
                     /locus_tag="FF957_RS15060"
                     /old_locus_tag="FF957_15060"
     CDS             complement(1396..1581)
                     /locus_tag="FF957_RS15060"
                     /old_locus_tag="FF957_15060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(1586..1924)
                     /locus_tag="FF957_RS15065"
                     /old_locus_tag="FF957_15065"
     CDS             complement(1586..1924)
                     /locus_tag="FF957_RS15065"
                     /old_locus_tag="FF957_15065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(2170..2778)
                     /locus_tag="FF957_RS15070"
                     /old_locus_tag="FF957_15070"
     CDS             complement(2170..2778)
                     /locus_tag="FF957_RS15070"
                     /old_locus_tag="FF957_15070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(3264..4163)
                     /locus_tag="FF957_RS15075"
                     /old_locus_tag="FF957_15075"
     CDS             complement(3264..4163)
                     /locus_tag="FF957_RS15075"
                     /old_locus_tag="FF957_15075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(4262..5728)
                     /gene="msr(A)"
                     /locus_tag="FF957_RS15080"
                     /old_locus_tag="FF957_15080"
     ARG             complement(4266..5728)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            6202..6876
                     /locus_tag="FF957_RS15085"
                     /old_locus_tag="FF957_15085"
     CDS             6202..6876
                     /locus_tag="FF957_RS15085"
                     /old_locus_tag="FF957_15085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001106064.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYVLSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <6934..7311
                     /locus_tag="FF957_RS15090"
                     /old_locus_tag="FF957_15090"
                     /pseudo=""
     CDS             <6934..7311
                     /locus_tag="FF957_RS15090"
                     /old_locus_tag="FF957_15090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            7308..8189
                     /locus_tag="FF957_RS15095"
                     /old_locus_tag="FF957_15095"
                     /pseudo=""
     CDS             7308..8189
                     /locus_tag="FF957_RS15095"
                     /old_locus_tag="FF957_15095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            8305..9234
                     /locus_tag="FF957_RS15100"
                     /old_locus_tag="FF957_15100"
     CDS             8305..9234
                     /locus_tag="FF957_RS15100"
                     /old_locus_tag="FF957_15100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            9227..9964
                     /locus_tag="FF957_RS15105"
                     /old_locus_tag="FF957_15105"
     CDS             9227..9964
                     /locus_tag="FF957_RS15105"
                     /old_locus_tag="FF957_15105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            9978..>10154
                     /locus_tag="FF957_RS15110"
                     /old_locus_tag="FF957_15110"
                     /pseudo=""
     CDS             9978..>10154
                     /locus_tag="FF957_RS15110"
                     /old_locus_tag="FF957_15110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            10211..10885
                     /locus_tag="FF957_RS15115"
                     /old_locus_tag="FF957_15115"
     CDS             10211..10885
                     /locus_tag="FF957_RS15115"
                     /old_locus_tag="FF957_15115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <11026..11661
                     /locus_tag="FF957_RS15120"
                     /old_locus_tag="FF957_15120"
                     /pseudo=""
     CDS             <11026..11661
                     /locus_tag="FF957_RS15120"
                     /old_locus_tag="FF957_15120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            11658..12188
                     /gene="sat4"
                     /locus_tag="FF957_RS15125"
                     /old_locus_tag="FF957_15125"
     ARG             11659..12185
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            12281..13075
                     /gene="aph(3')-IIIa"
                     /locus_tag="FF957_RS15130"
                     /old_locus_tag="FF957_15130"
     ARG             12282..13072
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            13351..13922
                     /locus_tag="FF957_RS15140"
                     /old_locus_tag="FF957_15140"
                     /pseudo=""
     CDS             13351..13922
                     /locus_tag="FF957_RS15140"
                     /old_locus_tag="FF957_15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(14091..14765)
                     /locus_tag="FF957_RS15150"
                     /old_locus_tag="FF957_15150"
     CDS             complement(14091..14765)
                     /locus_tag="FF957_RS15150"
                     /old_locus_tag="FF957_15150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            15027..15212
                     /locus_tag="FF957_RS15310"
     CDS             15027..15212
                     /locus_tag="FF957_RS15310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(15435..16013)
                     /locus_tag="FF957_RS15155"
                     /old_locus_tag="FF957_15155"
     CDS             complement(15435..16013)
                     /locus_tag="FF957_RS15155"
                     /old_locus_tag="FF957_15155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(16277..16657)
                     /gene="blaI"
                     /locus_tag="FF957_RS15160"
                     /old_locus_tag="FF957_15160"
     ARG             complement(16281..16657)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(16647..18404)
                     /gene="blaR1"
                     /locus_tag="FF957_RS15165"
                     /old_locus_tag="FF957_15165"
     ARG             complement(16651..18404)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.73"
                     /coverage="100.0"
     gene            18511..19356
                     /gene="blaZ"
                     /locus_tag="FF957_RS15170"
                     /old_locus_tag="FF957_15170"
     ARG             18512..19353
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(19882..20301)
                     /locus_tag="FF957_RS15180"
                     /old_locus_tag="FF957_15180"
     CDS             complement(19882..20301)
                     /locus_tag="FF957_RS15180"
                     /old_locus_tag="FF957_15180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            20425..21396
                     /locus_tag="FF957_RS15185"
                     /old_locus_tag="FF957_15185"
     CDS             20425..21396
                     /locus_tag="FF957_RS15185"
                     /old_locus_tag="FF957_15185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(21568..21660)
                     /locus_tag="FF957_RS15190"
                     /old_locus_tag="FF957_15190"
     CDS             complement(21568..21660)
                     /locus_tag="FF957_RS15190"
                     /old_locus_tag="FF957_15190"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(21817..22164)
                     /locus_tag="FF957_RS15195"
                     /old_locus_tag="FF957_15195"
     CDS             complement(21817..22164)
                     /locus_tag="FF957_RS15195"
                     /old_locus_tag="FF957_15195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(22183..22800)
                     /gene="cadD"
                     /locus_tag="FF957_RS15200"
                     /old_locus_tag="FF957_15200"
     ARG             complement(22187..22800)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(23916..24110)
                     /locus_tag="FF957_RS15210"
                     /old_locus_tag="FF957_15210"
     CDS             complement(23916..24110)
                     /locus_tag="FF957_RS15210"
                     /old_locus_tag="FF957_15210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            24220..24912
                     /locus_tag="FF957_RS15215"
                     /old_locus_tag="FF957_15215"
     CDS             24220..24912
                     /locus_tag="FF957_RS15215"
                     /old_locus_tag="FF957_15215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(25080..25229)
                     /locus_tag="FF957_RS15315"
     CDS             complement(25080..25229)
                     /locus_tag="FF957_RS15315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(25776..>26065)
                     /locus_tag="FF957_RS15220"
                     /old_locus_tag="FF957_15220"
                     /pseudo=""
     CDS             complement(25776..>26065)
                     /locus_tag="FF957_RS15220"
                     /old_locus_tag="FF957_15220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(26085..27068)
                     /locus_tag="FF957_RS15225"
                     /old_locus_tag="FF957_15225"
     CDS             complement(26085..27068)
                     /locus_tag="FF957_RS15225"
                     /old_locus_tag="FF957_15225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     ARG             complement(3268..4163)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(4263..5728)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(3265..4163)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             11671..12188
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             11063..11364
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             18512..19356
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(25573..25720)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          427..1169
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(25779..25954)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(26086..27068)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gacaaaaaac ctctttccat attttagttt ggtaagaggt aataaaacgt ttttatttag
       61 ctttacattt atttaatgat ttaggtgctt gcactaagat attattcatt atataataca
      121 agtatcgaaa attatataaa taaacagttt ctaaacgttt tattaccaaa ccccgactat
      181 taccagtagt tggggttttt gttatattaa gtttattata gcactttaaa taaacttata
      241 aaagggaaaa tatagcttta tcaagggttt ataaaccctt gataaatatc ataaaccttt
      301 cataaaccct tgataaaaag gttgatggat gtttattttt atttattaat cactttatta
      361 ttaagcatta taagcttata atattttatc aagggtttat aaacatttta taaagggttg
      421 atgatatgaa aagtgtgaaa aagttgagtg aagaattagg ggttagtaag caaacgattt
      481 ttaataatat taagcgattg aatatagaga caataaaaca ggaaaacact tcgtttatta
      541 aagaagatac cgatatagaa aaaatcattc aaagagtaaa tgaaaataaa aagaaatatg
      601 gttttgaaag tactactgaa gacaaacaaa aaaaagggtc ggataatatt aattttgaat
      661 cgaaaagcga tgctcaaata gtagaaatcc ttaaaaatca gattgatact ttaaataatc
      721 aaattgaaaa acaagaaagt cgtcatgaaa caacaattga attttacaga aaagagttgc
      781 aagaaagatc aaaattgctt gaaaatcagc aagttctggc attagagagt aataaaaaga
      841 ttcaaaaatt agaaaatcaa ttagaaaaag aaaaacacct taattatccc tttgatacat
      901 ctactaacac tagacaaaac gttgatgcac aagaaaaaac atatactact aatcctgtaa
      961 atattaacag agatcaggaa gaaactaaag aaacagagat tcaatataag gatatatctg
     1021 gaagtcaaag cgacgaaagt acacaaggtg aagaagcaaa aaaagaagac gttccagcta
     1081 atctaaatga caatgatagt gatatagaag aaaagagtga agaaacggaa cctaaaaagg
     1141 ggttttggag tcgtttgttt ggtagctaaa ataattgatt aggcactaaa agttataaaa
     1201 ttttagtgtc ttttatatag tgagaacttc tggtaatcat cgattatgta aactaaagta
     1261 tttcaaataa ttaactgtat taatactctc atcatgattg cgttataaac gttcgttatt
     1321 gagacaaaat ttaatagtac tactacacaa aaagagagtg cgaattcgca ctctcttttt
     1381 gtgataaatg aatggttaag aaaataattc atccacagtt gtatcaaaca atcttgccaa
     1441 cttaaatgct aatgtcaatg taggatcata tttattgttt tctattgcat taatagtttg
     1501 cctagacact tttaattctt tacttaaagt ttcttgagaa attccttttt gttttctata
     1561 ttctctaatt ctatttttca ttaatttaac ctttagatgt atatttttta tttgtagtat
     1621 agtaattaaa cagcataaga aatagtgcta caattataaa gaaaatttct ggatattgag
     1681 aaaaccaaga tccttcaata cttggtgaca aacctgtaaa tttaagcact agtgtaaata
     1741 acatacaata tacaatccaa ataaaacttt tagccagtat ttcaataaac attttacgtt
     1801 gtctttcatc gtatcgatct tgttgtcctt ttttatctaa tgtttctgaa ggtaaatatt
     1861 tgttagttat agccgtccat aaacaagaaa aaattaaaat aataataaaa ggaattaaat
     1921 tcattataac acctcataaa tgtaaaaagt atttgacatt tatgagtgta aatatttttg
     1981 atacaaatgt caaatacttt ttacattata atatatttta aaacacctta ttagtaaaac
     2041 aattactata tagaaagctg cgaactcgta ctcttttttc ttgtataatt attaaaatct
     2101 caattcaata atatgttatg gaatttgaga cactgtgaga gacgctcatt tgcattgaca
     2161 atcaatttat caagataatc ccttatcatg tttaattcta taaactgttt gtcttgtgat
     2221 attaacttct ttcgcaatct tactaatcgc tttgccttct tctaacattt ccaccacgcg
     2281 atgataaata acacgtttct gtgggtcttt agcatttggt gaataaagta aagggcgccc
     2341 tttatatacg cctttttcct tcgcaacttg aatcccttgc gcttgtcgac gtttactttc
     2401 atttctctct tgttctgaaa ccattgctaa tatttgaatg attaaatctt tcataaactt
     2461 atccagtaat ggattgccaa ttacttcatt catcataggt aagctggtaa tcattaactg
     2521 aacgtctttt tcttttaaat aattcacagt ttcaataatt tcatcatagt tacgtcctaa
     2581 acgatcaata gattccacaa cgaatcgatc tcccattctg acaaaattga gtgcttcttg
     2641 aaatacaggt ctattttcca ctgactttcc cgactgtttc tctgtaaaga ttttctccac
     2701 accaaacgtc tttaaattat ccaattgtct ttctaaattt tgatctatcg atgatactct
     2761 cgcataacct ataatcattc atcttcactc cataataaat atacacccta atcatacgtt
     2821 ttaattgtta taatttcaac aattcttttt gtatggttag ggtgtactca aagtgtacat
     2881 atctataatt aaaacttact aaaaataaat atagattttt tctttgtaac agaaccgttc
     2941 atttgaaggt catctctatc ataaatattt aaattaacta aaaattttaa tcatctgttt
     3001 aatacttatg aaatgtattt acggtaggta ttaaaattga tgaaatttat ataagtgctt
     3061 tcaatgaaaa tgaccgttta tttatcctcc tgatttaagg agttagaaat ttcgaaaacg
     3121 attctttcca tttgttgcat ttgttccatg tccagatatt taatacatta tagaaaacca
     3181 aagaccatca ctaattaaac gcagttttaa aatttcatca ggattgcctt cgtctttaaa
     3241 atgggcctct tttaatataa gttctactct ttcataccta actctttcaa tgccatcgtt
     3301 tcatacgccg attctcctga ttccatagca aactcagcga taaacattgg gaatactgca
     3361 ttgagttcta ttatatgctc tttcattcgt ggccatattt cacctccagc tttaccgtat
     3421 gctgttataa gttgctctaa tccttcgtcg tcgaatacac gatggtgtcc tataaagtcc
     3481 attgatgggt cggagtgggt tgcttcagtc cagtctatga gacctgtgac gtttgcttgg
     3541 ttatctacca ttatatgtcc tggatgtaag tccccatgta tcatggtcgc atgtcgaggc
     3601 catagttcgt cgttttctaa ccattgtttc catctgttcc ataattcatc tgatacgcca
     3661 taagtttctt taactttatt cattcttctt tgaaagtcat tttttatttc ttgtatggtt
     3721 ttgatattta tatgctgaac gttaatgttt tcttctggta tgttgtgtaa atctacgagt
     3781 gtttcagcta atgtgttaat aaagttttct ggtaatggtt tgtgttcaat ttcccataca
     3841 taattttgta tttctggatc tattgtggct gcgggtttac ctgtaagttt tgggtaagca
     3901 ataaggtctt ttgcatgtac tttccacttc ggtatttcaa atgaaacatt cttctgtaag
     3961 aagtctaccg tttgtttttc gggttttgtt cgtttataaa cgtcaggtct tcttggtagt
     4021 ctcaaaaccc attctactcc atgtttatct tttccaaatg caacttgaaa atcaagtccc
     4081 gattcattca atgagattgt ttgaggttgg atgtgtaatt gatatttttc tgcacattta
     4141 ataatttcat tatgtcgagt cattttattg gatccttatt tctattatat ttttcttgtg
     4201 aacgtatttt ttatattgat ataaatgaac ctaatattca atataaatta gtgtatagtt
     4261 tttaagttat atcatgaaga gattgtcctg ttaattccca ttttttatct gatacatgtt
     4321 taacaaacct tgtatcatgt gatgtaaaca aaatgattcc aggatattta ttcataaaca
     4381 tttctaatgc ttctaatgtt ttaatatcta aaaaattagt tggttcatcc aaaattaaca
     4441 tattcgcttt cgttgaaaat aatactgcta acgataattt cgttctttcc ccaccactca
     4501 aaacattaca agaacgatca agtgcttcat ttaaacccaa gttatttaaa atagctctac
     4561 tgaatgattc tgatgaatcc gtttcatcca ttaaatattg caataatgaa acgtcacgca
     4621 tgtcttcata agcaagttga cgatagtatg ccatttgcac tttaggagaa caatcaattc
     4681 cctctatttg gtggtaaata gcttcaagta aagttgtctt acctacacca tttgcaccta
     4741 cgagcgctat atttttgcca tatggtattt ggaatcgtac ttgtgttagc agtttttgac
     4801 ttcctttaac caatgttaga ttttgtgcaa tgattggata attattatgg atatcataaa
     4861 ttttattttg tgggaaattg aattcatgat aactttgtgg tttttcaact tcttccaaat
     4921 gttccattct tttttcaata tgcttagctt gtttttgagc agccttctca accgtgcctt
     4981 tttgttttga tgcacttaaa cgatctggtg ctatactttt gtttttttgt tttgatgatg
     5041 cttgtgccat ttgttgcgct tgatttcgtt tagctttact ggcttgggac aatctttgtt
     5101 tttcacttat atactgttca tattgacgtt gttgttctaa ctgttcttgt tcatattgat
     5161 tttgatactg tgtgtaatta cctttaaaca ctcttattgt gccatcttct tgtatatccc
     5221 aaattgtgtc agcaatttgg tctataagtg ctctatcatg acttactata attaaagtac
     5281 catagtaata ttttaaaata tttttcagat aatctttacc aattttatcc aagtgatttg
     5341 taggttcatc taaaagtaat atcggactat aatttgatat gacattagct aatttatatt
     5401 ttgctttttc accaccactc atactgtcgg ttgtatgcat aggtatatgg agttcactca
     5461 ttaaactacc gtctaacgtg ttaaaatcat tttccacatc catgttaagc tgttcaaaat
     5521 attgaatttc gccaaccgtt tcaactgttc cagattctgg ttttgttttt tgagcaatca
     5581 tatttagtaa tgtggttttg ccagtaccat tacccccaat aagtgctatt ttttcaaatt
     5641 ggtaagcgta aagatgaccg atgttaagtg atcgtaaatc tgtcaattta tgattgattt
     5701 ggttaaattt aattgtatat tgttccatat ttatacactc cttgtatatt taaaggacgt
     5761 gtacgcaaaa aaatgagaca ggctactccc gtctcattca cattacactt tcaaacactt
     5821 aaaaatttat tatgatgttt tagtatttga aagcgtttat tattcctatc gaaggataaa
     5881 aaatgacata agtcatccta tgagtgtgta ttgcggacaa gcctttttga attaatttag
     5941 ttttgtattc aaaaaggttt atttgagtct catagaagct gtcattttaa tcctccttca
     6001 tcgataaaat agtaatgtta atataacatt ttgttggttt ttttacaata tatctctaag
     6061 tagaaagatt atataacaaa agtataaaaa tacaatttta gattgattat acatctcctt
     6121 aatttagagt gtactcataa aatacggttc tgttgcaaag ttgaatttat aatataattt
     6181 taacaaaaag gagtcttctg tatgaactat ttcagatata aacaatttaa caaggatgtt
     6241 atcactgtag ccgttggcta ctatctaaga tatgtattga gctatcgtga tatatctgaa
     6301 atattaagag aacgtggtgt aaacgttcat cattcaacga tctaccgttg ggttcaagaa
     6361 tatgccccaa ttttatatca aatttggaag aaaaagcata aaaaagctta ttacaaatgg
     6421 cgtattgatg agacgtatat caaaataaaa ggaaaatgga gctatttata tcgtgccatt
     6481 gatacagagg gacatacatt agatatttgg ttgcgtaagc aacgagataa tcattcagca
     6541 tatgcgttta tcaaacgtct cattaaacaa tttggtaagc ctcaaaaggt agttacagat
     6601 caggcacctt caacgaaggc agcaatggct aaaataatta aagcttttaa acttaaacct
     6661 gactgtcatt gtacatcgaa atatctgaat aacctcattg agcaagatca ccgtcatatt
     6721 aaagtaagaa agacaagata tcaaagtatc aatacggcaa agaatacttt aaaaggtatt
     6781 gaatgtattt acgctctata taaaaagaac cgtaggtctc ttcagatcta cggattttcc
     6841 ccatgccacg aaattagcat catgctagca agttaaacga acactgacat gatatattag
     6901 tgattagcta tattttttac tttgcaacag aaccagccat ttaatatgac tgttacaatt
     6961 actaagattc aagcactatt acgccgcacg tatgatttca ccactcaagt taataattta
     7021 acagtagatg attgcgagtt actacttgat gcagcaaagc ttaaatttaa tgaagaaacc
     7081 atagacctga cacacactga attgcaaatc atgcatagct tattccagaa caagggcaaa
     7141 ttcgtcagtc gtaatgcgtt aatcgaaaaa tgctgggaat cagaacactt cattgatgac
     7201 aatacgcttg ctgtcaacat tacacgttta cgcaaaaagc tacaaaaact aggacttaca
     7261 gattttatcg aaacgaagaa aaatgtcgga tatcgtgtag gtgacgtatg aatttcttga
     7321 aatcaatcca acgtgaaatt tatattgtca tccttacttg tgctttattc tactttatat
     7381 tattcatgta taatgtgccg atgcaagcat atatgattgg tctaggtatt gtattgtttg
     7441 tttcaatgat ttactggggt atccattaca tgaactttaa aaaagaataa acactacagg
     7501 aacagaacga agatttaaga atcgaaaacc ataaacttcg taatgacttt attaactacc
     7561 aaagtgagtt agagtcatat tttttaatgt gggtgcatca aatcaagaca ccgattacag
     7621 catcaaagtt actgcttgaa gatcctgatg aacacgtgat ttctaacgtg cgtaatgaag
     7681 tcttacaaat tgataattac acgaatcttg cactgaacta tttgaaactc atgaaccaaa
     7741 agacatacat ggtctttatg gaagtgagtg tagatgaatt aattcgacca ctgattaaac
     7801 gttatgcgat acagtttatt catcatcaaa caaagttgca ttatgagaaa agtgaagcgg
     7861 ttatattaac agatgccaaa tgggcatcaa ttatgattga gcaaatatta aacaatgcat
     7921 taaaatatgc acgtggcaaa gatgtgtgga ttacgtttga cgaaaataca aagaaattat
     7981 caatccgaga taacggtatc ggcattaatg cgagtgattt accgaaaatc tttgataaag
     8041 gtttctcggg ctataacggt agaataagtg agaaatcaag cggtattggt ttatatattg
     8101 tcagcacaat ctcaaagcgc ttaggccata aagtaagtgc tacatctaca ttaaacgatg
     8161 gttcaatatt caccattcaa tttaaataac tccaatcttt catttttgta agattagcgg
     8221 ctgtttttgt aagaatagat aaaggcagcc ttttctaatc gcgcgtaaga taaaggtaac
     8281 aacaaactaa gaaaggtgcc agaggtgaaa aatttgaata atataattga aataaataac
     8341 ttaacaaagc aatatggaag tcagatagca gttaataatt tgagtataac tgttgaaagt
     8401 ggacaaattt atggtttttt aggaagaaat ggtgcaggca aaacaactac tataagaatg
     8461 cttttaggct taattaaacc tacgaaaggt aatattaaaa tatttgaaaa agagttcgaa
     8521 agtaataaaa ctgaaatttt aaaaaatatt ggtgctatgg ttgaaacgcc aggtttttat
     8581 agtaatttga cagctaaaga gaacttaact ataaatgcta aaatattagg tatacaaaaa
     8641 gaaaatgcaa ttgaagaagt gttagaaata gtaggactag cttctgaaaa agtaaaattg
     8701 tttaaaaatt attctttagg tatgaagcaa cgtttaggga ttgcgagagc tttattgcac
     8761 aatcccgaat tattgatact tgatgagccg acgaatggat tagatcctat tggcataaaa
     8821 gaaattagaa agttgattaa ggatctggct caatctagaa atataaccat tttaatttca
     8881 agtcatatat tgtcagaaat agagcagtta gtagacaagg tgggtattat tcataacgga
     8941 gttttgttag aagaaattat gtatgaagat ttaaaaaaaa agaacagaca atttataagt
     9001 atatcagtat cagatgaaga aaaagttgca tgtttgttgg aaactaactt cggaatttat
     9061 gactataaaa ttaaagaaaa tggcgaattt aaaatttatt cacatattga tagacaacaa
     9121 gaaattaata gattattagt attaaacaat attgatgttt tccagatgag agtgatagaa
     9181 gataatctag aaacttattt cgaagactta gtaggaggtg gcacaattgg ataatctact
     9241 ccgtacagaa tttattaagt taaaaagatc atatatgttt ctaataagta ttttaggtac
     9301 atgcgtagca ccttttatgg tggttgtagc ttcttttatt agtatgcgga cgaaagtacc
     9361 gactcctaat attgtattta aacagttatt tgaagaagtc agtttatatc atatgctaat
     9421 tattggacct cctctatatg gggttataat agcctatttg tttggaagag aatatataga
     9481 agatacttta aaaaacttat taattatacc tatatctaga gaaagttttt tagtaagtaa
     9541 aataatatta ttattcttgt ggattcaaac actatctgtt attgcatggt tgctaacttt
     9601 aatgctaggt atgctattgc attttcaagg gttaagccag agtttaataa ttgattcatt
     9661 ctttacattt gttattggcg gagtgttatt atggatatta tctccaccaa taattatttt
     9721 gtcgatatat tttaaaaatt atgttcccac aattgtttta accataataa ttactttgat
     9781 aaatttaatg actgctaatt ctgaacatag aggattattt ccttgggctg cagttggaga
     9841 catatctaga ggaacattac ctaatactta tccatttcta ttatctttaa ttatcataat
     9901 tgttacatct atattcagtg taattatatt attctcatac tttaaaaaaa ctgatataag
     9961 ttaaaaggag gagaaaaatg ggttttatag agcagattaa agcatttatt ttaggtgtag
    10021 ttgaagggtt gacagaattt gctccagtat catcaacagg tcatatgatt attgttgatg
    10081 atatgtggtt aaacactgct gacgatttag gaagtgcgtc tgcaactact tttaaggtgg
    10141 taatacagtt aggaggttct gttgcaaagt tgaatttata atataatttt aacaaaaagg
    10201 agtcttctgt atgaactatt tcagatataa acaatttaac aaggatgtta tcactgtagc
    10261 cgttggctac tatctaagat atgcattgag ctatcgtgat atatctgaaa tattaagaga
    10321 acgtggtgta aacgttcatc attcaacgat ctaccgttgg gttcaagaat atgccccaat
    10381 tttatatcaa atttggaaga aaaagcataa aaaagcttat tacaaatggc gtattgatga
    10441 gacgtatatc aaaataaaag gaaaatggag ctatttatat cgtgccattg atacagaggg
    10501 acatacatta gatatttggt tgcgtaagca acgagataat cattcagcat atgcgtttat
    10561 caaacgtctc attaaacaat ttggtaaacc tcaaaaggta attacagatc aggcaccttc
    10621 aacgaaggta gcaatggtta aagtaattaa agcttttaaa cttaaacctg actgccattg
    10681 tacatcgaaa tatctgaata acctcattga gcaagatcac cgtcatatta aagtaagaaa
    10741 gacaaggtat caaagtatca atacagcaaa gaatacttta aaaggtattg agtgtattta
    10801 cgctctatat aaaaagaacc gcaggtctct tcagatctac ggattttcgc catgccacga
    10861 aattagcatc atgctagcaa gttaaacgaa cactgacatg atatattagt gattagctat
    10921 attttttact ttgcaacaga accatcattt ttattaaaat actcttttgt aaaatctttc
    10981 tgctcttcaa tgtatttaat ttctttacct ctaaatctat tatagctatt tgatgattac
    11041 aataaaattg atcttacctt attgcccttg gaagagttag ataattacct aaagggcgat
    11101 aaattaataa aggttctaat tgataaagat tgtagaatta aaagggacat agttccgact
    11161 gatatagatt atcatgtaag aaagccaagc gcaagggagt atgatgattg ctgcaatgaa
    11221 ttttggaatg taacacctta tgttattaaa ggattgtgcc gtaaggaaat tttatttgct
    11281 attgatcatt ttaatcagat tgttcgccat gagctgctga gaatgatatc atggaaggtc
    11341 ggcatcgaaa caggctttaa atgaagtgta ggcaagaact ataagtttat tgaaaggtat
    11401 atatccgagg atttgtggga gaaacttttg tccacctacc ggatggattc ctatgaaaac
    11461 atatgggaag cattatttct atgccatcaa ttgttcaggg cggtatccgg tgaggtggcg
    11521 gaaaggcttc attatgccta tccggagtat gataggaata taacaaaata taccagggac
    11581 atgtataaaa aatacactgg taaaaccggc tgcctggata gcacatatgc cgctgatata
    11641 gaagagaggc gggaacagtg attacagaaa tgaaagcagg gcacctgaaa gatatcgata
    11701 aacccagcga accatttgag gtgataggta agattatacc gaggtatgaa aacgagaatt
    11761 ggacctttac agaattactc tatgaagcgc catatttaaa aagctaccaa gacgaagagg
    11821 atgaagagga tgaggaggca gattgccttg aatatattga caatactgat aagataatat
    11881 atctttacta ccaagacgat aaatgcgtcg gaaaagttaa actgcgaaaa aattggaacc
    11941 ggtacgctta tatagaagat atcgccgtat gtaaggattt cagggggcaa ggcataggca
    12001 gcgcgcttat caatatatct atagaatggg caaagcataa aaacttgcat ggactaatgc
    12061 ttgaaaccca ggacaataac cttatagctt gtaaattcta tcataattgt ggtttcaaaa
    12121 tcggctccgt cgatactatg ttatacgcca actttgaaaa agctgttttc tggtatttaa
    12181 ggttttagaa tgcaaggaac agtgaattgg agttcgtctt gttataatta gcttcttggg
    12241 gtatctttaa atactgtaga aaagaggaag gaaataataa atggctaaaa tgagaatatc
    12301 accggaattg aaaaaactga tcgaaaaata ccgctgcgta aaagatacgg aaggaatgtc
    12361 tcctgctaag gtatataagc tggtgggaga aaatgaaaac ctatatttaa aaatgacgga
    12421 cagccggtat aaagggacca cctatgatgt ggaacgggaa aaggacatga tgctatggct
    12481 ggaaggaaag ctgcctgttc caaaggtcct gcactttgaa cggcatgatg gctggagcaa
    12541 tctgctcatg agtgaggccg atggcgtcct ttgctcggaa gagtatgaag atgaacaaag
    12601 ccctgaaaag attatcgagc tgtatgcgga gtgcatcagg ctctttcact ccatcgacat
    12661 atcggattgt ccctatacga atagcttaga cagccgctta gccgaattgg attacttact
    12721 gaataacgat ctggccgatg tggattgcga aaactgggaa gaagacactc catttaaaga
    12781 tccgcgcgag ctgtatgatt ttttaaagac ggaaaagccc gaagaggaac ttgtcttttc
    12841 ccacggcgac ctgggagaca gcaacatctt tgtgaaagat ggcaaagtaa gtggctttat
    12901 tgatcttggg agaagcggca gggcggacaa gtggtatgac attgccttct gcgtccggtc
    12961 gatcagggag gatatcgggg aagaacagta tgtcgagcta ttttttgact tactggggat
    13021 caagcctgat tgggagaaaa taaaatatta tattttactg gatgaattgt tttagtacct
    13081 agatttagat gtctaaaaag ctttaactac aagcttttta gacatctaat cttttctgaa
    13141 gtacatccgc aactgtccat actctgatgt tttatatctt ttctaaaagt tcgctagata
    13201 gagttctata ttagagatgt aaagagtttt ggtgaagagg tttgtgagta tggcttttat
    13261 aaccagggtg caatgagaag cactaacagc agctagctta agaacgcata ggatatactt
    13321 tttatggaag tcacagagga ggaataaaat ttgaacagga ttaacagagt aacctctatt
    13381 cttattcagc tgcaatcaaa aaaataattc ctgccaaaga aattgcacag cgatttaata
    13441 taagcttaag gacagtttac agagatatcc ggacacttga agaagccgga ataccaattg
    13501 gatctgaggc cggaaaagga tattttcttg tagagggctt cctacttctg ccggtaatgt
    13561 ttacagcggc ggaagtgggt gcattgatta cagcagggaa atttttaaat tgccatggag
    13621 atgaatcatt tataaaggat tttgattcag ctatgtataa aatcaaatct attttgaagc
    13681 atggtgaaaa aaactatgca caggagttgg agaacagtat taacgtgtac agcacatctg
    13741 gacagaaaaa tacattggcg gataacgtta ttgcagcaat tcagactgca atctgcaata
    13801 aaagggtaat atcaattcaa tatcctgcat caggagggca agaaccggaa agcagaatga
    13861 tagagcctat atcactgggg ttttatgaac agaactggta cttaatcggt tttgcaggct
    13921 aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa agcatttgca tagaagaaga
    13981 gctctgtcaa agccatgatg gctctttgga acaaatatta aaacaaatgc tggttctgtt
    14041 gcaaagtaaa aaaatatagc taaccactaa tttatcatgt cagtgttcgc ttaacttgct
    14101 agcatgatgc taatttcgtg gcatggcgaa aatccgtaga tctgaagaga cctgcggttc
    14161 tttttatata gagcgtaaat acactcaata ccttttaaag tattctttgc tgtattgata
    14221 ctttgatacc ttgtctttct tactttaata tgacggtgat cttgctcaat gaggttattc
    14281 agatatttcg atgtacaatg gcagtcaggt ttaagtttaa aagctttaat tactttaacc
    14341 attgctacct tcgttgaagg tgcctgatct gtaattacct tttgaggttt accaaattgt
    14401 ttaatgagac gtttgataaa cgcatatgct gaatgattat ctcgttgctt acgcaaccaa
    14461 atatctaatg tatgtccctc tgcatcaatg gcacgatata aatagctcca ttttcctttt
    14521 attttgatgt acgtctcatc aatacgccat ttgtaataag cttttttatg ctttttcttc
    14581 caaatttgat ataaaattgg ggcatattct tgaacccaac ggtagaccgt tgaatgatga
    14641 acgtttacac cacgttccct taatatttca gatatatcac gataactcaa tgcatatctt
    14701 agatagtagc caacagctac agtgataaca tccttgttaa attgtttata tctgaaatag
    14761 ttcatacaga agactccttt ttgttaaaat tatactataa attcaacttt gcaacagaac
    14821 ctcatttact atatgggcat ctctttcatt attaatacaa agctttgtat ctccgatatt
    14881 aggcaaaggt gtaaacgaat taggtgatac tataggattc aacattatat taatcgtttc
    14941 tttaataatg attatcttct tattttttat aaatcgtagt aaaaatatct cctatgatta
    15001 tataaaagtt caaagaggtg aagccaatga ataaattaga aaaatggtct ttggtattta
    15061 ttatttttac atttctctct tcattagcac ttttatattt caaatataat tttagttcgg
    15121 ttatgccagt cctaagtctt tctattttaa ctatactaat attgttgacg agtattatta
    15181 ctgtagtttc agttaatgat gaagatactt aaaacgttca ttagtgaaac aggtattata
    15241 ttaaaaaagc gtacgaattt gtacgctttt ttcttgtgtt attattaaaa tctcataaca
    15301 ggaaaatatt atgagatttt agacgctgtc agaacgtctc ttttacatcg agtgacattg
    15361 aatcaaagtc tttgtatgtt aatgatatat aaaattattt agtagattca ttatagtaag
    15421 ctagattagt tgctctactt gtttttattc tcttttgcct ctaatttatt gagataacga
    15481 taaatagttg tacgtgaaac ttgccactgc tctgcaattg ttttaattgg cgtaccatta
    15541 tcataaagtg tcttaagtaa gtttaaatct tgtttattta atttttcagg tctacctcca
    15601 tatcggcctc tagcacgtgc tgcaattcga ccggctgatg atcgctctaa aattaaatta
    15661 cgttcaaact ctgcaaatgc tgcgaataaa tgaaataata attgtcctgt agaacttgat
    15721 ttatccatcg ttatattttc ttctaaacta tgaaaactca cacctcgttc gttaagttca
    15781 ttaactaacg tgattaaatc ctccatgttc cgtcctagtc tatctaatct ccaaacaaca
    15841 atcgtatctc ctgacctcgc aaattcaatt gctttatcta aaccaggtcg cttacttttt
    15901 gaaccactca tatggtcatt aaatatcttt tcacaaccat atgtatttaa tcgatcctcc
    15961 tgtaaattca aattttgtaa tccagttgaa actcttgcat aacctatttt caaaatacag
    16021 acctcctata tacaccttta gtgtaccata acttgattac gaggtctttt gtgaacatag
    16081 attttttgtt gggtttttga acacataatt ctatgtaata cttacttatt tagacaaaaa
    16141 acaagagtgt acagaaaatg gttattttct gtacactctc atctttaata atatatttta
    16201 aatgttatta acaaaactaa tttaataaga gtcaagcata gtttacatat gtattatgtt
    16261 tgaaacatat ctctaattac tttttactaa tatcatttaa aatgtctcgc aattcttcaa
    16321 tttctttgtt atttaattct tcatttttcg caaaattcag cactaaactt ttcatgtccc
    16381 ctccatacag tttattaaga aaggttttag cagttttcat tttaatatcg tcttctttaa
    16441 tatttgatga gtaaaaataa atattctctg atttgtatcg ttttataatc tcttttttat
    16501 atagtcttgt gattaatgtt ctaatcgttt tatcgctaac ttctttatat ttttgaattt
    16561 caactacaat ttcattagct gatactgatt ttttacccca tattatattc ataacatccc
    16621 attcagccat agatatttca acttgcttat tggccattta aaacacccat ttcttttaat
    16681 attttttcac tgattaattc agcatttttc ccagacgggt ttccatctga taaatgtgta
    16741 gcaaaataat acttatcatg atttgtaatt acgtaaccta caaaccaccc attattatac
    16801 ttcccgttta ctatacctgt acctgttttc ccatacagtt catacttttc atttttctta
    16861 atcaataatg aagaagataa ttgattcttt gcttttttac taaaatggtt attttgttcc
    16921 atcatatttt taaaaactat tacttgttca agattagata ttttcaaact atcttccatc
    16981 caatagcttt tataacttcc caaattttca ttaccataat ttaattgctt gagttgagcc
    17041 gcagtatagt tctttggtat ttgattacta atacgttcga agtaccaatt aactgaattt
    17101 tgcattgctg tatttaaatc ttgttcctta ttccaagact cgaaaagata atgtttatga
    17161 ttccatgaca tacgtgaatt tttatcactt ataatatgac ggtcaagtcc aaacagtgct
    17221 aaataaattt tgtaagttga atcaggagaa tatctttttc tactttcttt ttcattataa
    17281 atatagtatt tgtctttctt catgctgtac ataacgaaag atccactatt tgaaccaaaa
    17341 tttttacttt catctaaaat ttggtaatcg ctttgtaagg gctttttata attataatca
    17401 gttaaggatt gccccattaa aaactggctt tgaattatca tgataaaaaa agtaaaaata
    17461 caaataaaaa ttagaattaa ttttgactgc tttttcagat cggcttcttt tatattaatt
    17521 aatctacttt tgagtaatga ttttttacca ttaaatgaat ggcttaatat atttttgttg
    17581 gaaaatgggg tttttaatac ggagtccata atagattccg cataagtttt aaattcattt
    17641 ttgttaatat tattaaggac aaatctatcg gcttctactt cattgtcatg aattatcttt
    17701 ctttttacaa tatgtactaa tggattgtaa ctcataataa tagagaagat attaaagata
    17761 attaaatgta aagtatctct atttttagca tgagcatatt catgcagtat tatatatttt
    17821 agtcttttat caattacact tttaaaatat gaactaggaa tcaaaataat atatttccca
    17881 taccaaaaag ttattggaga ttgaatagcc tctgcttttc gaatcacaat atttttttta
    17941 tattgatggt tgaaaagtat cgtatctatt ttattttttt cattttcgtt tagataaagt
    18001 gactgtttct ttaaatattt aagatataat aaggctttca aaaatttaaa acttaaaata
    18061 ataactaaaa ctatccaaat aactgtgcag atattatcaa ttgaatccca attaaactta
    18121 tggatatctg ttgtgaactc ttgaataggt ttggtggtat ttatgttatg gttcaaatcg
    18181 tgtgacttac tttcaactgt gggcgcttga ttattcacat tattaaattt tataaaagag
    18241 aatttaattg ggataaaagg aattaatcca gcaagcatag ttagatacca aactttataa
    18301 tttaaactat aattaaaata gcgttttaat atgtacctaa aaaatactaa caatagaaat
    18361 ataaaacaaa agcttactac gctcattatt agtaatttag ccattttgac accttctttc
    18421 aaatatttat aataaacaat tgacatcaat attacaattg taatattatt gatttataaa
    18481 aattacaact gtaatatcgg agggtttatt ttgaaaaagt taatattttt aattgtaatt
    18541 gctttagttt taagtgcatg taattcaaac agttcacatg ccaaagagtt aaatgattta
    18601 gaaaaaaaat ataatgctca tattggtgtt tatgctttaa atactaaaag tggtaaggaa
    18661 gtaaaattta attcagataa gagatttgcc tatgcttcga cttcaaaagc gataaatagt
    18721 gctattttgt tagaacaagt accttataat aagttaaata aaaaagtaca tattaacaaa
    18781 gatgatatag ttgcttattc tcctatttta gaaaaatatg taggaaaaga tatcacttta
    18841 aaagaactta ttgaggcttc aatgacatat agtgataata cagcaaacaa taaaattata
    18901 aaagaaatcg gtggaatcaa aaaagttaaa caacgtctaa aagaactagg agataaagta
    18961 acaaatccag ttagatatga gatagaatta aattactatt caccaaagag caaaaaagat
    19021 acttcaacgc ctgctgcttt cggcaagact ttaaataaac ttatcgcaaa tggaaaatta
    19081 agcaaaaaaa ataaaaattt cttacttgat ttaatgttta ataataaaaa cggagacact
    19141 ttaattaaag atggtgttcc aaaagactat aaggttgctg ataaaagtgg tcaagcaata
    19201 acatatgctt ctagaaatga tgttgctttt gtttatccta agggccaatc tgaacctatt
    19261 gttttagtca tttttacgaa taaagacaat aaaagtgata agccaaatga taagttgata
    19321 agtgaaaccg ccaagagtgt aatgaaggaa ttttaatatt ctaaatgcat aataaatact
    19381 gataacatct tatagtttgt attatatttt gtattatcgt tgacatgtat aattttgata
    19441 tcaaaaactg attttccctt tattattttc gagatttatt ttcttaattc tctttaacaa
    19501 actagaaata ttgtatatac aaaaaatcat aaataataga tgaatagttt aattataggt
    19561 gttcatcaat cgaaaaagca acgtatctta tttaaagtgc gttgcttttt tctcatttat
    19621 aaggttaaat aattctcata tatcaagcaa agtgacaata gcattttaca agtatttttt
    19681 attgttcgat tagggtaaac ctaaataata cataaattat attacaatat gtttattata
    19741 gaggctaaag tatcttagaa atttggatag taggtttttc gggaataaaa gtatagttgg
    19801 ctttaatata taattaagct aagctatcat ttatatttac tcgattataa ttcgcacttc
    19861 aactttttta taacgtaaaa attaaaacgt agttttattt atctttagta atatcttttt
    19921 aaacactaca gtttcttcat tagttaaatt agcgaagtaa tgattattaa gttgataggc
    19981 tttcttttct aatgttggcc ataagtcttt tgctttattt gtactgttta ttagcacagt
    20041 tcttctattt tcattatcag tttgacgtgt tattagatcc tttttggaca tcttatctaa
    20101 tattccagat attgttgaag gttctaaatt taaagtatta ccaatcgctt taggtgtatt
    20161 caaattacta ttaatcaagc aattcaaaac accatattct gctggagtaa tattataggg
    20221 acttaataaa cttttaaaat gtttaaaaac tctattctga gaagtactca acaaataatt
    20281 tatacaatta tctaattcca caactaaaac ctctcttaaa tcattagtat tgactcgctt
    20341 atcatatcat gataagtttt gtaggaaaat agttttgcaa caaaaacata cttctacaaa
    20401 acaattgtga aagaaggcta ataaatgttc aatgcggtag tagtgagaaa aagtgcatca
    20461 aatgttagtt ataaagtaga aaaagttgat gaatctcatt tatcgaaggg tgatgtatta
    20521 gtaaaagtgg tatactcttc aataaattat aaggatatgc tagctttaca atataaaggc
    20581 ggtgtaatta gagattatcc tatgattcct ggtatagatt ttgcaggtat tgttgaatca
    20641 agttcgaatg ataagtttaa agaaggcgat aatgtattag ttactggtta tgatgttggc
    20701 gtgacacata caggtggatt ttcagaatat gcacaagtgc ctggagagtg gattgttcct
    20761 attccccaag aaatgtctat taaagagtct atggtatatg gcacagccgg ttttacggca
    20821 gcattatcaa tttttgaact agaaaaatat ggaatgaata tcaaatcaca acctgaaatt
    20881 ttagtgtctg gggctacagg tggtgtgggc agtgttgcta tacaaatttt acataaaatt
    20941 ggatatgaaa atatcactgc tatcgtaaga aaagaaaagc aaatagaaat cgcaaaaaaa
    21001 ttaggtgcaa aacaagtaat aataattgaa gatgataata aaccgcttaa aaaaggtatt
    21061 tttgattatt tcttagatac agtggggagt aatgtaacat tatacggttt aaaacgtcta
    21121 aattatcaag gtgttgctac tgtatgtgga aatgtagcag gaaattcact taacgctaat
    21181 atattaccgt ttattcttag aggtattaaa ttaattggca ttgattctgt atatgttgat
    21241 cataatatcc gtgaagatat atggagtaag ttagcaaatg aatggaatat aggaaattca
    21301 cttctataca atgaaattgg atttgaagaa ttctataaaa cgatagatca gcttttaaaa
    21361 ggacaacatt taggaagaac tattttaaaa gtataagtgt gagtattcat taatacattt
    21421 actattaatt caatcatttt gcatttctct actaaccagt gttataattt atataacgaa
    21481 aatgattaac aattaatgca ccaatcccca cactattgca gtagtgtggg gattttttcg
    21541 atgctggctt ataaagtcgc ctattaatta tttgttgcgt ttactaagcc aataagtata
    21601 atacgcaaca gcacagccac tgatgactgg tgctatgatg tgaacgaaaa tgattagcaa
    21661 agtaatgcac ctcctctctt cgtcaattga cgcctgagag ataggcgact ctattattat
    21721 accatctgtg aatatacaag catatctact tccgataagt cgtcttatgt tatataactt
    21781 tgttttttat agtatcaaga caagaagaaa ctcgtttcaa aaaccctcat gatttttaga
    21841 gaaaaactct cttatttcat cgtctttaat aaaataatat gccatctttc catctttata
    21901 aaaatcaagt acctcatttt tatataaaag ccttaaatga tgtgaagttg aagcaacact
    21961 cattttcaat atcaaagaaa tatcacaaac acacaactca tcttctttaa tcaaagataa
    22021 tatgattttc aatttcttct catcacaaat tttttctaaa atgttaagta atttcttaga
    22081 tttatcatct tctaaaaaac ttaaagcatt gttaacttta tcctcatgta cacagatcac
    22141 atcacaagta ttttcataac tcatataaaa tcacacccta aattaaaata taaatcctaa
    22201 aattgtttga atagtgtcat tttcaataat aataaataaa cctaaagcta tataaataat
    22261 agccataatc caacgactaa atttctcaac aatttctcca attcctggaa tattagctaa
    22321 tttttgtgca gtaaacacca agaagaaaat taaaattaaa aagacaaaca gagtaagtaa
    22381 taaattagta acacttaatg tcacaaaata cggaacaaat aaaccaatat tatcggcgcc
    22441 acaacttgct atcgtaacaa ttgcaaccgt accaactaat ttagacaatc ctttttcatt
    22501 caattctttt ttagctctct tttctccttc acaatcatca taaatagcca ctttaattcc
    22561 aagataaatt ggtattaaac ccaataaacc taatatccac ttttctggaa cataatttaa
    22621 tacaaaagct aaaaacaaac taactaatat taaaataata gaccctaaat attgaccaac
    22681 ataaatatct ctatattctt ttctagtctt tgctctagca aaaaatatta ataaaattac
    22741 taataaatca actgctgtag caatataaag aacagcagca gcaacaaccg tttgaatcat
    22801 aatacacctc attcaaaaat atttttgaat gtattataac ttatattttt aaataatcat
    22861 aggtgcttta ttccaattgc tttattgacg ttgagcctcg gaacccttaa caatcccaaa
    22921 acttgtcgaa tggtcggctt aatagctcac gctatgccga cattcgtctg caagtttagt
    22981 taagggttct tctcaacatc aataaatttt ttcggcataa atgcgtgtct atgcgtagac
    23041 atggagacac ttcagaatta tggagtgatt acatgagttt aactattttt ctttattcag
    23101 ttttaggaag tttattagca aattatatct acgaaaaatc ttcaaaataa ataacttttt
    23161 cggttctact ttgtacactt tatctacctg gtagacctaa ttgttattgc tttacaggtc
    23221 taaaattcgt cgttataatc tagttaaatc ccgtaagggc gcacttatac gtcggataaa
    23281 tcgacatgtg caaaaacgta atcgaccttc gtcgattttt ttatttcaaa attaaagaaa
    23341 cggcttgaga tattccgagc agttataaaa attaatttgc gttgaatatt gctactacat
    23401 tcttgaaaaa gtgatgtaga tttatagccc ataacttttt tgaattacat cgacgatacg
    23461 gcgtcgaaag aaaaataaat agaccgtatg aaagaaaaag ctacctcact ttatctgggg
    23521 tagcttttat tttttatgcc cttattttga attttaagag ggcattttaa agatttaggg
    23581 gtgattcata tagttttata tctaaaactt atatatgctt ttaaaacgca aatatgagcc
    23641 aaataaatat atgctatttt caaaaacaaa aatttgagca aaaacaataa ctatttttag
    23701 acactgccca tttacatgca aattaaaaat tagcataaaa ttctttaaaa cttccccacg
    23761 tttttctaaa ttcctgtagg gcgtttttat caaaaatcaa gacaagaaga aactcgttca
    23821 cactcgtttc aaaaaaacaa gaaatctaat ctatacacct accgttttcc aaccccctca
    23881 aagcatacaa attaaaaaca aaattattca taatcttact ttcttttaac aaaaacataa
    23941 aaaccataaa tagacaaatt aactatcaaa ggcaataaac agtataaaaa aaccacgaat
    24001 aaatcttcat caacatctaa aataaaaaag aataaaacaa ttaacaaaat actaattaac
    24061 aaacctaaaa gtggcaaact ttttatatat ttttctaaat tttcattcat aaaatagact
    24121 cctttcaaaa atatgtttat aaatatatta aaataaatat tgattttata aagcgcttac
    24181 ttatacaatt aaaatatctt attatcttgg aggtatcaaa tgaaaattat aaaattattt
    24241 tcaataattt ccttgttcct actggtattt agcgcgaatt tttctaatgc ttacgcaaat
    24301 gaagaacaaa aaagttcttt actagaaaat caaaaagaaa aattgaaaag caaaaacatc
    24361 gaagtatcac aaatgaccaa gaaagaaata agttttctag aacaattgca aaataaaaat
    24421 gaagatatgc aaaaattcga aaagcaaatg aaaaaagaag gatttaaaaa aataaagcta
    24481 gaagacaaaa attctaaatt aaaatatcta gctacagaag caaatgataa aaatgcatat
    24541 ggctacatag ctaataacgc ttataaaaat gaaaaaacaa aagaaattgt agtttctgaa
    24601 acaatatatg ataactacaa caaaaaaatc acaaaattca ttgccgaaaa aagaagtatg
    24661 actgaaaaca aagagggaaa aatacttatt aacaaaaatt acgttgaata taaggctgaa
    24721 aaagttgata aaaacagacc ggtaacatat gcaggattca aatggaacgg caaagcattc
    24781 gcttgtagta tggctggact ttatgcatgt gctcactact gtggagtatg ggcaatcgta
    24841 aatccaatag ccggcggtgt atgtgaagca gtttgcggaa ctgcatttgc agctggatgc
    24901 tctgtaggtt gattttattc caattgtttt attgacgttg agcctcggaa cccttaacaa
    24961 tcccaaaact tgtcgaatgg tcggcttaat agctcacgct atgccgacat tcgtctgcaa
    25021 gtttagttaa gggttcttct caacatcaat aaattttttc ggcataaata cgatgttcct
    25081 tatttatcct cataaaaaac aatagctgaa atatataacc aattactgtg tgtttgaatt
    25141 tctaatacat gaatatcatt ctttaaaaac ctattaactt gtttatctaa ttgacgatga
    25201 gtaaaagtag cgaaagtttt aatcttcatg atatctctcc ttttataaaa atagcaatcc
    25261 ttattacaat attaaacact tttattttgg attttaagag gcattttgaa gacttagagg
    25321 caaatcatat aggttttgta cttaaaaatc tatacagtct cttaaaacgc aaatatgagc
    25381 caaataaata tatgctaatt tcacaaacaa aaatttcagc aaaatcagtg actaattttt
    25441 tagatactgc ccatttacat gcaaatttaa aaattagcat aaaatacttt aaaacttccc
    25501 catgtttttc taaattcctg cagggctttt cttatcaaaa acttagaaat tttaatttaa
    25561 ctctaaaatc tccgtaagag cataagggaa atttgctatc attcaaaaat gatagatctg
    25621 gcaaggccag acattccaag ggttttaagt tattttaaag tgatatcata caaagctgta
    25681 gtgtcacact tttgtgacac tacatacagc atttgtcaca aaaataagac agcacttttt
    25741 tacagaaaaa caataaaaaa agacatcagt tatcactaat gtcttaaata ataattttgc
    25801 ttttcgaaat tccaaattgc ggtaattgaa tgtgcttttt ttcttcgtct gtcgttttat
    25861 cttcatcact tgtattaatc aaattaccat cttcggcatc gtctaagttt aaaattttat
    25921 gcttttgttt aagcaatcca ccataactta acatacgttt tcgatacaaa cctttttcta
    25981 aatcacttac aatttcttga tttttttcgt cgtcatcagt taaaaagtca gatgatttaa
    26041 cggaatattt tgatgtctct tcgagtgtta taaaatcatt tgaattattg attaaagata
    26101 ttatattgtt tcatgttttt acggcgcata taaagggcat gtgtttcttc aagttcagtt
    26161 agaattgttt gcattaaata agcttgcatt gacttgattg tttccttttg gcctttaact
    26221 cccctatcat gtatagcttt tttaagtctt tttaaagaag ttaatatttc atcctcaatg
    26281 tcctctaaca tgtaatgcat atcttcatgc cttgaattaa atgatttttt tgctttaaga
    26341 ataacagcct ttatgatttc taaatctcta taatcatatt ttaataaata attagttagt
    26401 tgttctggga attcttgcaa tagcatttct ttatcatcaa aattatgtgt aaattgattt
    26461 gaatgatttg aatgattact aatttcattt ttgtacttta tatcattcaa gtcattcata
    26521 tcattattct cagtatcatt aaagtcaatg tcattaaagt cagtatcatt agtgttcgat
    26581 tttcgaactt ctggacgttc gattttcgaa cttctggacg ttcgattttc gaacttctgg
    26641 acgttcgatt ttcgaacttc cttctcgccg taaggttcaa catcgttttc ttctttttct
    26701 attttgtaaa tatcacgttc tgtgacaata ggtttcatta aatatagaat atttggttta
    26761 tttaaaccac gtcgtttttg aatgagtaga ccatcgtttt ctaacccttt ttttattttt
    26821 gttaactttt cttttttaca atttaagatt tccattagct tttcatttga ataaacaaag
    26881 taaatgttac catcttcatc aacccagcta tttttaatag ataaatttaa gcgatcacgt
    26941 aagatagcat aggctatttt catatcatta gttagatttt tataattttc actggtaaag
    27001 aatactttag ggatttgata aaatctttct ttgtaatttt cttgcactgt aaaatattga
    27061 ttttgcat
//
