LOCUS       NZ_CP040267             7464 bp    DNA     circular CON 21-JUN-2024
DEFINITION  Escherichia coli strain 631 plasmid pEc631_4, complete sequence.
ACCESSION   NZ_CP040267
VERSION     NZ_CP040267.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN10784800
            Assembly: GCF_008642395.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7464)
  AUTHORS   Grevskott,D.H., Salva-Serra,F., Lunestad,B.T., Moore,E.R.B. and
            Marathe,N.P.
  TITLE     Complete sequencing of ESBL-producing Escherichia coli isolated from
            the environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7464)
  AUTHORS   Grevskott,D.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAY-2019) Contaminants and Biohazards, Institute of
            Marine Research, Nordnesboder 3, Bergen 5005, Norway
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.0.
            Assembly Name                     :: Ecol_631
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008642395.1-RS_2024_06_21
            Annotation Date                   :: 06/21/2024 03:13:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,297
            CDSs (total)                      :: 5,175
            Genes (coding)                    :: 4,990
            CDSs (with protein)               :: 4,990
            Genes (RNA)                       :: 122
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 185
            CDSs (without protein)            :: 185
            Pseudo Genes (ambiguous residues) :: 0 of 185
            Pseudo Genes (frameshifted)       :: 56 of 185
            Pseudo Genes (incomplete)         :: 135 of 185
            Pseudo Genes (internal stop)      :: 40 of 185
            Pseudo Genes (multiple problems)  :: 43 of 185
            Pseudo Genes (short protein)      :: 1 of 185
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040267.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7464
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="631"
                     /isolation_source="marine environment"
                     /host="Bivalve mollusk"
                     /db_xref="taxon:562"
                     /plasmid="pEc631_4"
                     /geo_loc_name="Norway"
                     /collection_date="2014-10/2015-11"
     gene            join(6118..7464,1..312)
                     /locus_tag="EST51_RS26805"
                     /old_locus_tag="EST51_26790"
     CDS             join(6118..7464,1..312)
                     /locus_tag="EST51_RS26805"
                     /old_locus_tag="EST51_26790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007372656.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_001529697.1"
                     /translation="MKIVIVGGVAGGASAAARARRLSEDVSIVVFERGSDVSFANCGLP
                     YHIGGKIPLRQSLILKTPEDFKSRFNIDVRIRHEVMSVDPVNKMVTVKNLTSGEVYTEE
                     WDRLLLSTGAAPVVPPLPGLQEAGVFTLRNLTDMDAIQAWIEQHNIAHTTLVGGGFIGL
                     EVMEALSERGISVTLLEMGEQVMAPVDPEMASALHQEIRSHGVDLRLRTALTEVLRTET
                     GFRVALSDGGFLQTDMVILAIGVKPESSLATGAGLAVGKRGGISVNACMQTSIPDIYAV
                     GDAVETPDLVFQEPANVPLAGPANRQGRIAADNMLDRHSLYHGSQGTSICKVFSLSIGS
                     VGANEKQLKAHGTRYEKVYVHAADHASYYPGATMISLKLLFSPDTGKILGAQASGKKGV
                     DKRIDVLAVVQRAGLTVNDLEHLELTYAPPFNSARDVVNQAGMVAANVIKGDTVICHVR
                     DVLQREPGSYCLLDIRSPAELKQFGEYPDALSIPLDSLRENLDKLPEDKEIIIGCQSGL
                     RGHVAYRMLQSHGFRTYNLSGGFITWQAVTESMSQ"
                     /name="FAD-dependent oxidoreductase"
     gene            1659..2552
                     /locus_tag="EST51_RS26815"
                     /old_locus_tag="EST51_26800"
     CDS             1659..2552
                     /locus_tag="EST51_RS26815"
                     /old_locus_tag="EST51_26800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_150395074.1"
                     /translation="MSAVLQRFREKLPHKPYCTNDFTYGVRILPKDIAILARFIQQNQP
                     YAQHWLAFDVDRMGAAIDWSDRNCPPPNITVKNPCNGHAHLLYALWLPVRTAPDASASA
                     LKYAAAIERSLCEKLGADVNYSGLICKNPFHREWQVAEWREDAYTLDELADYLDLSASA
                     CRSIDKNYGMGRNCHLFEMTRKWAYRAIRQGWPVFSQWLDAVIQRVEMYNASLPVPLSP
                     PECRAIGKSVAKYTHRKFSPEGFSAVQAARGRKGGTKSKRVAVPTSARSLKPWEALGIS
                     RATYYRKLKCDPGLAK"
                     /name="replication initiation protein"
     gene            complement(2756..3154)
                     /locus_tag="EST51_RS26825"
                     /old_locus_tag="EST51_26810"
     CDS             complement(2756..3154)
                     /locus_tag="EST51_RS26825"
                     /old_locus_tag="EST51_26810"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_150395075.1"
                     /translation="MRISNIEWLKKRIGFIRKLGEQTARQRQIIDLLDNEDGLTEQERK
                     LLHVLATAEKNDLQAQENERKQTIQKRIEGKKQRRERNHRLFLAAGLLIEAGLVDTKTG
                     ELRYKKDRILQALKEIKYDLETSPNPDA"
                     /name="hypothetical protein"
     gene            3331..4257
                     /locus_tag="EST51_RS26830"
                     /old_locus_tag="EST51_26815"
     CDS             3331..4257
                     /locus_tag="EST51_RS26830"
                     /old_locus_tag="EST51_26815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_150395076.1"
                     /translation="MATYHLSVKFGGKGQAANHADYIGRKGEYAKRKDLEYTEHGNMPE
                     WARDNPSHFWQAADQFERANGSTYRELEIALPRELTPEQRLELVQDFVRQEAGERHAWS
                     FAIHNPKASIDGGEQPHAHIMMSQRVNDGIERTPEQYFRRYNARYPERGGAKKDSGSLT
                     LTQQKEQLRELRKRWEVKHNEHMRKHGFERGFIDCRTLKEQGIERRPEVHLGFEAAGRL
                     DDAQRHDIMQKRSEPDYSRHLEQARTVGHDIREWLDTPVKQHELVRRLQHDVAREHGFD
                     MRDRVSRQNRTAPERVKSPSRGFSMGF"
                     /name="MobA/MobL family protein"
     gene            4260..4793
                     /locus_tag="EST51_RS26835"
                     /old_locus_tag="EST51_26820"
     CDS             4260..4793
                     /locus_tag="EST51_RS26835"
                     /old_locus_tag="EST51_26820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001679938.1"
                     /translation="MASTEEKLLTLLLSVEHLQHTAMEQQKAVADSLAVARETLRGYRD
                     ISDGVAKQVRDEVRNEVQKLDVAGLIGERISQDFQRLEESVANMKANADALNRDIATIH
                     SNIVQEYNTLKGYSWKWLGGVSVAFLVMFCVLGWGMKTILDRNYNATAAVYQKVVTLED
                     KLAEKPVTGKSRKN"
                     /name="hypothetical protein"
     gene            complement(4847..5068)
                     /locus_tag="EST51_RS26840"
                     /old_locus_tag="EST51_26825"
     CDS             complement(4847..5068)
                     /locus_tag="EST51_RS26840"
                     /old_locus_tag="EST51_26825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_130085482.1"
                     /translation="MTKLGENIPHIIDAAVDFMASSQAFREYLKKLPPDNTIPPDLTDE
                     HVPLYIRRLEYYRRLYRPKQTESYWKKR"
                     /name="hypothetical protein"
     gene            complement(5610..5957)
                     /locus_tag="EST51_RS26845"
                     /old_locus_tag="EST51_26830"
     CDS             complement(5610..5957)
                     /locus_tag="EST51_RS26845"
                     /old_locus_tag="EST51_26830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329508.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_150395077.1"
                     /translation="MPMNEDTKRQTDMKNAALGAADVLRGLANSDRLLLMCQLSQGEAN
                     VTELEAAVGITQPTLSQQLGVMRRLKLVETRRAGKMVYYRIGDNRIMTLLNTLYDLYCP
                     QADPNKVKKQP"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     Typing          1660..2552
                     /name="rep_cluster_2150"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          3332..4254
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="95.455"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ggcgatacgg tcatctgtca tgtccgcgat gtgttacaac gggaaccggg cagttattgt
       61 ttacttgata ttcgttctcc tgcggaactg aaacaatttg gtgaatatcc tgacgcgcta
      121 tccatccctc ttgattccct gcgggagaat cttgataagt tgcctgaaga taaagagatt
      181 attatcgggt gtcagagtgg tctgcggggg catgtggcat accgtatgct tcagtctcac
      241 ggcttccgga catataatct gagtggtggc tttataactt ggcaggcggt tacggaatca
      301 atgagtcaat aagagatgag gtgccataca catggcacct catcttccag attcattgaa
      361 aacgtattat atggaataga aatctacaaa aataattaac gccctggatg gtaccctatt
      421 gcgataatgt ggactgttca aaaaacaggc ttaccgtaca ataattctct atatccaaac
      481 tgaccccaat gttcctgaat gtaaatctcc gtacaaagat atcgttgagt tttatataat
      541 tcattgtttt tattgtgttt tgtttttttg ttgtgctggt ttgtagttat aaaaaacccc
      601 tgggaatcca ggggtaggta aggaaaacaa atgatactca gttagtgttg cactttaaac
      661 gggttgaagt ataactcgta ttaaatgaga tgttgaaaat aagtgaaaac cattgctggt
      721 tgcaataggg cagtatgcgt aaaaaataaa tttgtgatgc ttttcaaaaa aacaattaat
      781 acatgaatat tacagctcat atattacagt ttataaaaaa actgtgtttt atctattaca
      841 tagagaaaaa ttcttatcct gagctgtgaa cttggttgtt tcgtttgata tatatctttg
      901 taaatgtggt ttattatgcg ggcatttttt attgagtatt gaatcagaat aagtgatgca
      961 gctaaattta tttgcgtaac tatttcattg tcaatattct gactcaatct gacacctatc
     1021 gtttctcttg gattccccac ttttgtggtt tttttatccg gaacgggata gtgccagttg
     1081 ttttttatca gcctcagggt attttggggc ggctgcgaac attgacgcat tccacaacta
     1141 aaaaaaattt ctcacagact ctgattcttg ccccgacccc aggtcggttt ttttttgtcc
     1201 tggcgaaacg tgaagctctg aaacagaaaa tctccgggca gaaccttcca tccgggggga
     1261 gaaaacttgt cgttttgagc cgtccggtgt tcagaacgca cgaaaccgat cgcacatcgc
     1321 tttcgtgcat agttatgcaa cgccctgaaa acgattctga cgcgtttttc tggtttggcc
     1381 tggtgttttc ttgtcttttt gcgttttttg cgccagaaag cgactgaggg cgttttaagg
     1441 ggtacgtaca acgggagtta tggtaaatgg atcgggtttt cgggaaggtt cgacaggatt
     1501 tgccgttggg tgtagtgtaa gcgactgaaa aacaaacgcc ccgtaaatcg tgctctcacc
     1561 gccaagattg accacgaaat tacagggcgc tgggttccgc gtctcccgat gggaaagcgc
     1621 ggttagttaa actgtgttcc cgataggaat cgtatcacat gagcgccgta cttcaacgct
     1681 tcagggaaaa attaccgcac aaaccgtatt gtacgaacga tttcacgtac ggcgttcgca
     1741 ttctgccgaa agacattgcc atccttgccc gcttcatcca gcagaaccag ccatatgcgc
     1801 agcactggct tgcctttgac gtggaccgga tgggagctgc gattgactgg agcgaccgga
     1861 actgtccgcc cccaaacatc accgtaaaaa atccctgtaa cgggcatgcg catctgctct
     1921 acgcgctctg gcttccggtg agaaccgcgc cggatgcatc ggcttcggcg ctcaaatacg
     1981 ctgccgcgat tgaacgttcg ctgtgtgaga aacttggcgc agatgtgaat tacagcgggc
     2041 tgatttgcaa aaatccgttc caccgggaat ggcaggtggc tgaatggcgg gaagatgcct
     2101 acaccctcga tgaactggcg gattatcttg atttgagcgc ctcagcgtgc cgtagcatcg
     2161 ataaaaacta tggcatgggg cgaaactgcc acctgttcga aatgacgcgc aaatgggctt
     2221 acagggcgat tcgtcagggc tggcctgtat tctcacagtg gcttgatgcc gtgatccagc
     2281 gtgtcgaaat gtacaacgca tcgcttcccg ttccgctttc accgcctgaa tgtcgggcca
     2341 ttggcaagag cgttgcgaaa tatacacaca ggaaattctc accagaggga ttttccgcag
     2401 tacaggctgc tcgaggtcgt aagggcggaa ctaaatccaa gcgcgtagcc gttcctacat
     2461 cagcacgttc gctgaagccg tgggaggcat tagggatcag tcgagcgacg tactaccgaa
     2521 aattaaaatg tgatccaggt ctcgcaaaat gagaccagat aagccttatc agataacagc
     2581 gcccttctgg cgtctttttg agcagtaggt cttttgccgt ttttccccgt tcagccctgc
     2641 aatggtgctg ttttccgcat gattgtgctg gtagtgctcg ccgcagtctc atgaccgagc
     2701 gtagcgagcg aatgagcgag gaagcaccag ggaaccggaa cacggatgga ggcacttacg
     2761 cgtctgggtt tggggatgtc tccagatcgt acttaatttc cttaagtgcc tgtaatatcc
     2821 tgtctttttt atagcgtagc tcgcctgttt ttgtgtctac cagtcctgct tcgatcagta
     2881 gcccagccgc gagaaagagt cggtgattgc gttcccgtcg ttgttttttt ccctcgattc
     2941 gtttctggat cgtctgtttt cgctcgttct cctgtgcctg taagtcgttt ttttccgctg
     3001 ttgccagcac gtggagaagt ttgcgttcct gttctgtgag tccgtcttcg ttgtcgagca
     3061 ggtcaataat ctgtctctgt cgcgcggtct gttctccgag cttcctgatg aatccgatcc
     3121 gtttcttcag ccattcgatg ttgctgatgc gcatgttcgt gatgctccct ggtgtttttt
     3181 gcggtgtgtt gtggtcgtgc agtatatcgc ttgcggtcgc tgggtgcagg ggggtatctt
     3241 ccgtgctaat tctaaaaatt agaaggaagc gcacttatat gtttctctcc ttcgtcgaga
     3301 aacagtgcgc tcctgcggag ggctgaaacc gtggcaacct atcacctcag cgttaaattt
     3361 ggaggcaagg gacaggctgc aaaccacgcc gattacatcg ggcgcaaagg ggagtatgcg
     3421 aaacggaaag atctggaata cacggagcac ggaaacatgc cggaatgggc cagggataat
     3481 ccttcccatt tctggcaggc ggctgaccag tttgaacgtg cgaacggttc gacctatagg
     3541 gaacttgaaa ttgcattacc ccgtgaactg acaccggaac agcgccttga actggtgcag
     3601 gattttgtac gtcaggaagc tggcgaacgg cacgcctgga gttttgccat tcacaatccg
     3661 aaagcgagca ttgacggcgg cgaacagcct catgcgcata tcatgatgag tcagcgtgtg
     3721 aatgatggca ttgaacgtac accggaacag tatttccggc gctataacgc caggtatccc
     3781 gagcggggag gtgcgaaaaa ggattccgga agcctgactc tcactcagca aaaagagcag
     3841 ttgcgggaat tgcgaaaacg ctgggaggtg aagcacaacg aacatatgag aaagcatggc
     3901 tttgaaaggg gcttcattga ctgccggacg ctgaaagaac agggcattga acgacgtccc
     3961 gaagtgcatc tgggttttga agctgccgga cggcttgatg atgcccagcg tcatgacatc
     4021 atgcaaaaac ggtctgaacc ggactattcc cgccatcttg aacaggcgcg aacggtcggg
     4081 catgacatca gggaatggct ggacactccg gttaagcaac atgaactggt cagaaggctg
     4141 caacatgatg ttgcgcggga gcatggcttt gacatgagag acagagtgag cagacagaac
     4201 cgaactgcac ctgaacgggt taaatcaccg tcacgtggat tttctatggg attctgaaca
     4261 tggccagcac agaagaaaaa ttactcacgc tcctgttatc ggtggagcat ctgcaacata
     4321 ccgcaatgga gcaacagaaa gctgttgctg attctctggc tgtggcaagg gaaactcttc
     4381 gcggatatcg ggatatttct gacggtgtgg caaaacaggt cagggatgaa gtcagaaatg
     4441 aggtgcagaa gctggacgtg gcaggactga taggtgagcg catcagccag gattttcagc
     4501 ggctggaaga gtcagtcgca aacatgaagg caaacgcgga tgccctgaac agggatattg
     4561 cgacaattca cagcaatatc gtgcaggaat acaacaccct taaagggtat agctggaaat
     4621 ggctgggtgg ggtgtcagtg gcttttctgg ttatgttctg tgtgctcgga tggggaatga
     4681 aaacaatact cgacaggaac tacaacgcca cagcggcggt gtatcagaaa gttgtgacac
     4741 tggaagataa actggcggag aaacctgtca cgggtaagag ccggaaaaac tgacgcgctt
     4801 cgtttgtcca acgcctcacg acccgcgaaa ggatttcgcg aaccgttcac cgttttttcc
     4861 aatatgattc tgtctgcttt ggtcgataaa gccgtcgata gtattccagc cttcgtatat
     4921 ataacggtac gtgctcatca gtaagatctg gcggtattgt gttatcaggg ggaagttttt
     4981 tcagatactc acgaaatgcc tggcttgatg ccataaaatc tacagctgca tcgataatat
     5041 gtgggatatt ttcacctaat tttgtcatga tgattgatct gatattatca cggttcgtga
     5101 attatagtat gtcactatta tttatgcgtt agtgaaccag aaaaaatccc ccgttggcat
     5161 agggggatat gtaaggagaa ataacttcgc aggtgttctt gtttgtatta caacgtgaaa
     5221 agaatgcacg caacttaatt aatctgccgt acttcctttc agttttcaag ataaggttta
     5281 taataaaaca tggaatggaa gcaagcttta aggtttcagc tctaaaattt ttaatatcta
     5341 ttaactagct agttgttgtc cttgtgagca tgttgtatat aaaagccagg ataatatcct
     5401 gaccggagta ttcatattcc ttatcccctc tgtgctctca gaggtttttt tctgtattta
     5461 atgatatgag ctggaatgcg attccggccc ccccgtttac ataattctcc ctgacatacg
     5521 gcaccggaat cgcattgatt ttgcattgct aatgtctaac tgtgctggtg aatgttgggg
     5581 gcagtttgga tatcgaaaat tattgtacgt taaggttgtt ttttgacctt gttggggtcc
     5641 gcctgcgggc agtagagatc atataaggta ttcaacaacg tcatgatgcg gttatccccg
     5701 atacggtaat ataccatttt acctgcccgt cgggtctcga ccagcttcag gcgacgcatg
     5761 acacccaact gctgagacag ggtcggctga gtgataccga ccgccgcttc cagctcggtc
     5821 acattcgctt ccccctggct taactgacac atcaacaata gccggtcgct gttggccagt
     5881 ccccgtagga catctgctgc ccccagggct gcatttttca tatcagtctg acgttttgtg
     5941 tcttcattca tgggcattgc tggtttctta tattatgtat ttttatataa tattgttaag
     6001 tataatgata gtggcgtaat tttgccaccg tgatcttcag gtctgcagcg tccagctgga
     6061 ccgggtaact aattatatat ggcagatatt ttgccccgag tgaacagaga ggatgtaatg
     6121 aaaatagtga ttgttggtgg tgttgccggg ggagcatccg ctgcagccag ggctcgtcgg
     6181 ttatcagagg atgtcagtat tgttgtgttt gagcggggaa gcgatgtctc tttcgccaac
     6241 tgtggattgc cttatcatat aggcggaaaa attccgttac ggcagtcgct gattctgaaa
     6301 accccggagg attttaaatc ccgttttaac atagacgtcc gtatccgtca tgaagtgatg
     6361 tcagtagacc cggttaataa gatggtgacg gttaaaaatc tgacctccgg ggaggtctat
     6421 accgaagaat gggatcgtct gctcctcagt accggtgccg ctccggttgt tccccccttg
     6481 cccggactac aggaagcggg tgtctttaca ctgcgaaatc ttactgacat ggatgctatc
     6541 caggcgtgga ttgagcaaca taatatcgct cacaccacgc ttgtcggggg gggatttatc
     6601 gggctcgaag tgatggaggc actgagcgaa agggggatca gtgtgaccct gctggagatg
     6661 ggggaacagg ttatggctcc ggttgatcct gaaatggcat cggccctgca tcaggaaatc
     6721 aggagtcatg gcgtggatct gcgtctcaga acggcgctca ccgaggtact gcggacagag
     6781 acgggattcc gcgttgcgct gtctgacggt gggtttctgc agaccgacat ggttattctc
     6841 gccatcgggg taaaacctga gagcagcctt gccacaggag ccgggctcgc cgtgggtaaa
     6901 cggggaggca taagtgtcaa tgcctgtatg cagacaagta tccctgacat ctatgccgtg
     6961 ggggatgcag ttgaaacacc tgaccttgtc tttcaggaac ccgctaatgt tcctctggca
     7021 gggccagcca accgccaggg acgcattgct gctgataata tgctcgatcg tcacagcctt
     7081 taccatggca gtcaggggac atccatttgt aaggtatttt cgctgagtat tggcagtgtc
     7141 ggggcgaatg aaaagcagct gaaagcccat ggtacccgat acgagaaggt ttacgtccat
     7201 gccgctgatc atgccagtta ctacccgggg gcaacaatga tcagcctgaa actgctgttc
     7261 agccccgata ccggtaaaat tctcggggcc caggcgtcag ggaaaaaagg ggttgataaa
     7321 cgcatcgatg tcctggctgt cgtacagcgc gcggggctta ccgttaacga tctcgagcat
     7381 ctggagctga cctatgctcc gcctttcaac agtgcaaggg acgtcgttaa ccaggctgga
     7441 atggtggcgg caaatgttat caag
//
