LOCUS       NZ_CP039301            17924 bp    DNA     circular CON 19-JUN-2024
DEFINITION  Escherichia coli strain PigCaeca_1 plasmid unnamed3, complete
            sequence.
ACCESSION   NZ_CP039301
VERSION     NZ_CP039301.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN11268909
            Assembly: GCF_004801575.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17924)
  AUTHORS   REHAB consortium,T.
  TITLE     The impact of sequencing depth on the inferred taxonomic composition
            and AMR gene content of metagenomic samples
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 17924)
  AUTHORS   Shaw,L.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2019) Modernising Medical Microbiology Consortium,
            University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU,
            United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 30x
            Sequencing Technology :: Hybrid assembly: Illumina HiSeq 4000 and
            PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004801575.1-RS_2024_06_19
            Annotation Date                   :: 06/19/2024 07:24:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,850
            CDSs (total)                      :: 4,728
            Genes (coding)                    :: 4,527
            CDSs (with protein)               :: 4,527
            Genes (RNA)                       :: 122
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 14
            Pseudo Genes (total)              :: 201
            CDSs (without protein)            :: 201
            Pseudo Genes (ambiguous residues) :: 0 of 201
            Pseudo Genes (frameshifted)       :: 56 of 201
            Pseudo Genes (incomplete)         :: 140 of 201
            Pseudo Genes (internal stop)      :: 40 of 201
            Pseudo Genes (multiple problems)  :: 28 of 201
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP039301.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..17924
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="PigCaeca_1"
                     /isolation_source="feces"
                     /host="pig"
                     /db_xref="taxon:562"
                     /plasmid="unnamed3"
                     /geo_loc_name="United Kingdom: Yorkshire and the Humber"
                     /lat_lon="53.91 N 1.03 W"
                     /collection_date="2015"
     gene            join(<17043..17924,1..870)
                     /locus_tag="E7Z58_RS24215"
                     /old_locus_tag="E7Z58_24225"
                     /pseudo=""
     CDS             join(<17043..17924,1..870)
                     /locus_tag="E7Z58_RS24215"
                     /old_locus_tag="E7Z58_24225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /name="Tn3-like element TnAs1 family transposase"
     gene            complement(1491..1931)
                     /locus_tag="E7Z58_RS24220"
                     /old_locus_tag="E7Z58_24230"
     CDS             complement(1491..1931)
                     /locus_tag="E7Z58_RS24220"
                     /old_locus_tag="E7Z58_24230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011161230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005119689.1"
                     /translation="MAWHTVQETLKLTGKSRSQLYRDMAKGLVSYRTGKNDRREFETSE
                     LIRAYGELRTSETPKRHKEGHSKSVVSQAENAQLDVIQQKLDALQQTVTLMLEDKMARE
                     AENRLRNEEREQLQAEISRLADALAQEKKRGFWSRLFRSGSE"
                     /name="hypothetical protein"
     gene            2149..2538
                     /locus_tag="E7Z58_RS24225"
                     /old_locus_tag="E7Z58_24235"
     CDS             2149..2538
                     /locus_tag="E7Z58_RS24225"
                     /old_locus_tag="E7Z58_24235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000102614.1"
                     /translation="MSTELNSGTVGGFGHMGPNDPYNDGHSGSGSSGGSFNGGGNGGHD
                     NSSGSSYTASFGLITGRHPITVPGTKNINSVDLSAVINNIIHHEGARNNMYLDTANNVR
                     VGVTGTGWQCLATAGISAEGKRTFR"
                     /name="hypothetical protein"
     gene            2582..>2986
                     /locus_tag="E7Z58_RS24230"
                     /old_locus_tag="E7Z58_24240"
                     /pseudo=""
     CDS             2582..>2986
                     /locus_tag="E7Z58_RS24230"
                     /old_locus_tag="E7Z58_24240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /name="IS91 family transposase"
     gene            complement(3093..3929)
                     /locus_tag="E7Z58_RS24235"
                     /old_locus_tag="E7Z58_24245"
     CDS             complement(3093..3929)
                     /locus_tag="E7Z58_RS24235"
                     /old_locus_tag="E7Z58_24245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="WP_000480968.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKP
                     IEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIA
                     AELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNA
                     SELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIA
                     QMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY"
                     /name="aminoglycoside O-phosphotransferase APH(6)-Id"
     gene            complement(3929..>4204)
                     /locus_tag="E7Z58_RS24240"
                     /old_locus_tag="E7Z58_24250"
                     /pseudo=""
     CDS             complement(3929..>4204)
                     /locus_tag="E7Z58_RS24240"
                     /old_locus_tag="E7Z58_24250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase APH(3')"
                     /name="aminoglycoside phosphotransferase APH(3')"
     gene            complement(4279..4752)
                     /gene="dfrA14"
                     /locus_tag="E7Z58_RS24245"
                     /old_locus_tag="E7Z58_24255"
     ARG             complement(4283..4752)
                     /name="dfrA14"
                     /gene="dfrA14"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA14"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(<4773..5300)
                     /locus_tag="E7Z58_RS24250"
                     /old_locus_tag="E7Z58_24260"
                     /pseudo=""
     CDS             complement(<4773..5300)
                     /locus_tag="E7Z58_RS24250"
                     /old_locus_tag="E7Z58_24260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /name="phosphotransferase"
     gene            complement(5361..6176)
                     /gene="sul2"
                     /locus_tag="E7Z58_RS24255"
                     /old_locus_tag="E7Z58_24265"
     ARG             complement(5365..6176)
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            7366..7515
                     /locus_tag="E7Z58_RS24490"
     CDS             7366..7515
                     /locus_tag="E7Z58_RS24490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001138880.1"
                     /translation="MPSEYDEQLDSTDTQLPGEYDLFDLMAQVTEENLHAPVDFGSPVG
                     REAL"
                     /name="hypothetical protein"
     gene            complement(7889..9466)
                     /locus_tag="E7Z58_RS24270"
                     /old_locus_tag="E7Z58_24280"
     CDS             complement(7889..9466)
                     /locus_tag="E7Z58_RS24270"
                     /old_locus_tag="E7Z58_24280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing methyl-accepting chemotaxis
                     protein"
                     /protein_id="WP_001323889.1"
                     /translation="MRQNLPVTGRNLELPKDANILSTTSPQSHITYVNPDFIKISGFTE
                     EELLGQPHNIVRHPDMPPAAFEHMWSTLKSGRSWMGLVKNRCKNGDHYWVSAYVTPIAK
                     NGSIVEYQSVRTKPEPEQVLAAEKLYAQLRSGKAARPKLAASFSVKILLLIWGSIISSA
                     MAAGMLTDTSISSLLLATLMSGSLSSVSVLAILSPLGRLVERARNISNNPLSQSLYTGR
                     TDEFGQIEFALRMMQAETGAIVGRIGDASNRLSEHTRGLLKDIESSNVLTVEQQAETDQ
                     IATAVNQMVASIQEVASNAQHAADAAGRADTETASGQRLVAHTSQSITALEGEIRQATQ
                     VIHELEGQSNEISKVLDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAA
                     RTQQSTTDIQSMISALQERAQSAVTVMEQSSRQAHTSVAHAEEAATALDGIGQRVNEIT
                     DMNAQIATAVEQQGAVSEDINRSIINIRDAADTNVQTGQNNLQSAKSVAQLTSALSELA
                     KQFWEKRG"
                     /name="PAS domain-containing methyl-accepting chemotaxis
                     protein"
     gene            9776..10336
                     /locus_tag="E7Z58_RS24275"
                     /old_locus_tag="E7Z58_24285"
     CDS             9776..10336
                     /locus_tag="E7Z58_RS24275"
                     /old_locus_tag="E7Z58_24285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220837.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001161490.1"
                     /translation="MQGHRIGYVRVSSFDQNPERQLEQTQVSKVFTDKASGKDTQRPQL
                     EALLSFVREGDTVVVHSMDRLARNLDDLRRLVQKLTQRGVRIEFLKEGLVFTGEDSPMA
                     NLMLSVMGAFAEFERALIRERQREGIALAKQRGAYRGRKKALSDEQAATLRQRATAGEP
                     KAQLAREFNISRETLYQYLRTDD"
                     /name="recombinase family protein"
     gene            10340..13306
                     /locus_tag="E7Z58_RS24280"
                     /old_locus_tag="E7Z58_24290"
     CDS             10340..13306
                     /locus_tag="E7Z58_RS24280"
                     /old_locus_tag="E7Z58_24290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /protein_id="WP_001138014.1"
                     /translation="MPRRLILSATERDTLLALPESQDDLIRYYTFNDSDLSLIRQRRGD
                     ANRLGFAVQLCLLRYPGYALGTDSELPEPVILWVAKQVQAEPASWAKYGERDVTRREHA
                     QELRTYLQLAPFGLSDFRALVRELTELAQQTDKGLLLAGQALESLRQKRRILPALSVID
                     RACSEAIARANRRVYRALVEPLTDSHRAKLDELLKLKAGSSITWLTWLRQAPLKPNSRH
                     MLEHIERLKTFQLVDLPEGLGRHIHQNRLLKLAREGGQMTPKDLGKFEPQRRYATLAAV
                     VLESTATVIDELVDLHDRILVKLFSGAKHKHQQQFQKQGKAINDKVRLYSRIGQALLEA
                     KESGSDPYAAIEAVIPWDEFTESVSEAELLARPEGFDHLHLVGENFATLRRYTPALLEV
                     LELRAAPAAQGVLAAVQTLREMNADNLRKVPADAPTAFIKPRWKPLVITPEGLDRKFYE
                     ICALSELKNALRSGDIWVKGSRQFRDFDDYLLPAEKFAALKREQALPLAINPNSDQYLE
                     ERLQLLDEQLATVTRLAKDNELPDAILTESGLKITPLDAAVPDRAQALIDQTSQLLPRI
                     KITELLMDVDDWTGFSRHFTHLKDGAEAKDRTLLLSAILGDAINLGLTKMAESSPGLTY
                     AKLSWLQAWHIRDETYSAALAELVNHQYRHAFAAHWGDGTTSSSDGQRFRAGGRGESTG
                     HVNPKYGSEPGRLFYTHISDQYAPFSTRVVNVGVRDSTYVLDGLLYHESDLRIEEHYTD
                     TAGFTDHVFALMHLLGFRFAPRIRDLGETKLYVPQGVQAYPTLRPLIGGTLNIKHVRAH
                     WDDILRLASSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRIERTLFILDWLQSVEL
                     RRRVHAGLNKGEARNSLARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYL
                     ERATQGLVEAGKPVDGELLQFLSPLGWEHINLTGDYVWRQSRRLEDGKFRPLRMPGKP"
                     /name="Tn3-like element TnAs1 family transposase"
     gene            13364..13606
                     /locus_tag="E7Z58_RS24285"
                     /old_locus_tag="E7Z58_24295"
     CDS             13364..13606
                     /locus_tag="E7Z58_RS24285"
                     /old_locus_tag="E7Z58_24295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000844627.1"
                     /translation="MKTAALDLARERQAHEAGARTRATAHERTPQQERQKAAREAERGR
                     EAWTLGQGMKKPVAGCYGRLTRWKGGGDVVYMALL"
                     /name="transposase"
     gene            complement(13638..14288)
                     /gene="tetR(A)"
                     /locus_tag="E7Z58_RS24290"
                     /old_locus_tag="E7Z58_24300"
     CDS             complement(13638..14288)
                     /gene="tetR(A)"
                     /locus_tag="E7Z58_RS24290"
                     /old_locus_tag="E7Z58_24300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /protein_id="WP_000164043.1"
                     /translation="MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHF
                     RNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHAGTR
                     PGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGDSDAGERGGTVE
                     QAPLSPLLRAAIDAFDEAGPDAAFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD"
                     /name="tetR(A)"
     gene            14394..15593
                     /gene="tet(A)"
                     /locus_tag="E7Z58_RS24295"
                     /old_locus_tag="E7Z58_24305"
     ARG             14395..15590
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(15625..16509)
                     /locus_tag="E7Z58_RS24300"
                     /old_locus_tag="E7Z58_24310"
     CDS             complement(15625..16509)
                     /locus_tag="E7Z58_RS24300"
                     /old_locus_tag="E7Z58_24310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058717.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="WP_000058717.1"
                     /translation="MSLRTPDLLFTAIAPAIWGSTYIVTTQYLPNFSPMTVAMLRALPA
                     GLLLVMIVRQIPTGIWWMRIFILGALNISLFWSLLFISVYRLPGGVAATVGAVQPLMVV
                     FISAALLGSPIRLMAVLGAICGTAGVALLVLTPNAALDPVGVAAGLAGAVSMAFGTVLT
                     RKWQPPVPLLTFTAWQLAAGGLLLVPVALVFDPPIPMPTGTNVLGLAWLGLIGAGLTYF
                     LWFRGISRLEPTVVSLLGFLSPGTAVLLGWLFLDQTLSALQIIGVLLVIGSIWLGQRSN
                     RTPRARIACRKSP"
                     /name="EamA family transporter"
     gene            complement(16647..17039)
                     /locus_tag="E7Z58_RS24305"
                     /old_locus_tag="E7Z58_24315"
     CDS             complement(16647..17039)
                     /locus_tag="E7Z58_RS24305"
                     /old_locus_tag="E7Z58_24315"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013053.4"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="WP_001351729.1"
                     /translation="MLFPNFSLGEEYEHAPPATNRQISPYLPSGRFRTGLPVEGLAIER
                     GDLFYACPRASVFYGTALDADLRTRGVSTLVMAGISTTGVVLSSVAWASDADYDVRLVQ
                     DCCYDPDRDAHEALLRSGFGGRVQVV"
                     /name="isochorismatase family cysteine hydrolase"
     ARG             complement(3097..3929)
                     /name="aph(6)-Id"
                     /gene="aph(6)-Id"
                     /gene_name="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(4759..5300)
                     /name="APH(3'')-Ib"
                     /gene="APH(3'')-Ib"
                     /gene_name="APH(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.43"
                     /coverage="67.42"
     ARG             complement(3930..4174)
                     /name="APH(3'')-Ib"
                     /gene="APH(3'')-Ib"
                     /gene_name="APH(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="30.34"
     Typing          7158..7331
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="99.429"
                     /coverage="100.0"
                     /evalue="1.19e-84"
     Typing          complement(6628..7234)
                     /name="rep_cluster_2335"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.919"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 tacggtagcg agccgggacg gctgttctat acccatatct ccgaccagta cgcgccgttc
       61 agcacccgcg tggtgaatgt cggcgtccgc gattccacct atgtgctcga cggcctgctg
      121 taccacgagt ccgacctgcg gatcgaggag cactacaccg acacggccgg cttcaccgat
      181 cacgtctttg ccctgatgca cctgctaggc ttccgcttcg cgccgcgcat ccgcgacctc
      241 ggcgaaacca agctgtacgt gccgcagggc gtgcaagcct acccgacgtt gcgcccgctg
      301 atcggcggca ccctgaacat caagcacgtg cgtgcccact gggacgacat cctgcgcctg
      361 gccagctcga tcaagcaggg caccgtcacc gcctcgctga tgctgcgcaa gctcggcagc
      421 tacccgcgcc agaacggact ggccgtggcc ctgcgcgagc tgggccggat cgagcgcacg
      481 ctgttcatcc tggactggct gcaaagtgtt gaactgcgcc gccgcgtgca tgccggcctg
      541 aacaaaggtg aggcgcgcaa ctcgctggcc agggcggtgt tcttcaaccg ccttggggaa
      601 atcagggatc ggagcttcga gcagcagcgc taccgggcca gcggcctcaa cctggtgacg
      661 gcggctatcg tgctgtggaa cacggtgtac ctggaacgcg ccacccaggg gttggtcgag
      721 gccggcaagc cggtggacgg cgagctgctg caattcctgt cgccgctggg ctgggagcac
      781 atcaacctaa ccggcgatta cgtctggcgg cagagccgca gactggaaga cgggaagttt
      841 cggcccttac ggatgcccgg aaaaccttag cgtacgattt tttccgaatt ctgcgggctc
      901 cccattttga ggttgaaaaa taatcaacca tggcgggtga tttacgcagg ttaaggggag
      961 atcgtgacaa aaaaagcgtt cctcactgta tcgttcatgc ctgcatgaac gggttattct
     1021 tcctgactac agaattacat cgctccttca gttcatacat cacttttaca tcacttatac
     1081 atcactttta catcacttat acatcacttt tacatcattc cttcagctca tacgtcactt
     1141 tcatcctctg tgccatttgt acatcacccc cttcctgaac gtgctgacag cgggttttcc
     1201 ggctgcgccg gcaacgcttc acggccacgc aataaattgc gtccccgttc accgttttcg
     1261 gatgggaaga acgccggaaa caggacttac cccggctgaa tggtgtgaat ttccgcgcta
     1321 tgcacttgtg cgcatactca tgcatgccgt aaaaacagag cctgcgcgtt tctggcgggt
     1381 tttcgggtgg tttgttgcct gttttaccgg tttcccgtca gaaacgccct gagggcctct
     1441 caggcggtgc tgataacaga tgttatggta aatcagagtc acctgcactg ttactctgaa
     1501 ccggagcgaa acagccgcga ccagaatccc cgcttttttt cctgtgccag cgcgtcagcc
     1561 agacggctaa tttcggcctg tagttgttcc ctctcctcat ttcgcaggcg gttttctgct
     1621 tcccgcgcca tcttgtcttc aagcattagg gtaacagtct gctgcagagc gtccagtttc
     1681 tgctgaatga cgtctagctg agcattttcc gcctggctaa cgacagattt ggagtgtccc
     1741 tccttgtgcc tttttggtgt ctcagaagtg cgcagctcgc cataggcccg aatcagttca
     1801 ctggtctcga actcccggcg atcatttttt cctgtgcgat agctgacaag gcctttagcc
     1861 atgtcacgat ataattgcga gcgcgacttt cctgttaatt tcagtgtctc ttgaactgtg
     1921 tgccatgcca taaaagtgac agtgtctcct gtgtgtaccg tattgtaaca gcagaacata
     1981 ttactgtttt aacacaaaag gtctgaggct gcccgtgagg cgtgaaaaat acacaaaaaa
     2041 cctgttgacg gtgtggtttt gacgggcgta gtatttcgaa tactgtatat aaacacattg
     2101 ttataaatac agtttttgct gtttttaaaa gtcaaagagg ataattttat gagtacagag
     2161 ttaaatagcg gtactgtcgg tggttttggt cacatgggac caaatgaccc ctacaatgat
     2221 ggtcatagcg gctctggaag ttcgggaggt agttttaacg gtggtggtaa tggtggccat
     2281 gataatagta gtggttcatc ttatactgca tcctttggtc tcatcactgg ccgacacccg
     2341 ataactgtcc caggtacgaa gaatattaat tctgtcgatc tttctgctgt cattaataac
     2401 attatacatc atgaaggtgc acgcaataac atgtacctag atactgcgaa caatgtaaga
     2461 gtgggagtga cgggcactgg ctggcaatgt ctagcaacgg caggcatttc ggctgagggt
     2521 aaaagaactt tccgctaagc gatagactgt atgtaaacac agtattgcaa ggacgcggaa
     2581 catgcctcat gtggcggcca ggacggccag ccgggatcgg gatactggtc gttaccagag
     2641 ccaccgaccc gagcaaaccc ttctctatca gatcgttgac gagtattacc cggcattcgc
     2701 tgcgcttatg gcagagcagg gaaaggaatt gccgggctat gtgcaacggg aatttgaaga
     2761 atttctccaa tgcgggcggc tggagcatgg ctttctacgg gttcgctgcg agtcttgcca
     2821 cgccgagcac ctggtcgctt tcagctgtaa gcgtcgcggt ttctgcccga gctgtggggc
     2881 gcggcggatg gccgaaagtg ccgccttgct ggttgatgaa gtactgcctg aacaacccat
     2941 gcgtcagtgg gtgttgagct tcccgtttca gctgcgtttc ctgtttgggg tcgtttgcgg
     3001 gaaggggcgg aatcctacgc taaggctttg gccagcgata ttctccggtg agattgatgt
     3061 gttcccaggg gataggagaa gtcgcttgat atctagtatg acgtctgtcg cacctgcttg
     3121 atcgcggccg cgatagctag atcgcgttgc tcctcttctc catccgcgtt ccaagctgcg
     3181 gaaaggcacc cataagcgta cgcctggtcg agcaggcgac gcggatcgac gtccagcgca
     3241 cgagagaatg cgtccgccat ctgtgcaatg cgtctaggat cgagacaaag gtcgtctctg
     3301 tcagccggat cgtagaacat attggcggcg ccaaagccca cttcaccgac cagaccgacg
     3361 ggatctatca ccagccagcc gcgactggag aacatgatgt tttcatgatg cagatcgcca
     3421 tgtagcccac gcagttccga ggcattgctc atcatttgat cggctataat cgccgcgtgg
     3481 acgtagtcag tttgacaacc tgcgttttga tcatcgcgcg cccgctgaaa caaagctgca
     3541 aagcgatccc ggatcgggag aagggcagaa ggcaggggtt cctcagatgc ggcatacagc
     3601 ttcgccatta gttccgctgc aatttcggtc gcctggtagt cgccgtgctc ggcaacgatg
     3661 tgagagagca ttcgctcccc ggcatattcg agcaacatca gattgttctc acgaccgagc
     3721 aaccggactg ctcccctccc attgcgccat accagatagt cggccccgcg cagttcatca
     3781 gcaatgtctt ctataggttt caatcccttg acgattgcag gagtcccgtc tggcaatgaa
     3841 actttccaaa cgaggctgga aaaggtgtcc gcaatgagaa caggttgcga aacgtgccaa
     3901 tgagcaggaa aaacaggcgg catgaacatc aaccccaagt cagagggtcc aatcgcagat
     3961 agaaggcaag gcgttcgcgg tcgggggctt cgatccccaa tacattgaat aggacagcga
     4021 aggcgcgctc tgcttcatct ggcgctgccc agttctcttc ggcgttagca atcatgagtg
     4081 ccaaatcggc atagcgatct gctgttccga gccgcccaag gtcgatcaga cccgtgcatt
     4141 gaagagtttt agggtccacc atgaagttcg gcatgcaggg atcaccatgg caaacaacca
     4201 tatcgtcgct atcaatcgcg gaaaaaggcg tagtgcgcga agcgaacgaa gctttttgcc
     4261 gtcgattgca tagctttgtt aacccttttt ccaaatttga tagcaatagt taatgtttga
     4321 agtaaagtgt tgctcaaaaa caacttcgaa ggtatttgga atactcggga agaaaacatc
     4381 cccctctggc tcgatgtcga tcgtcgataa gtggagcgta gaggccatgg gtaatgtttc
     4441 tcggtaaatt tctccgccac cagacactat aacgtgaccg gtgaattcag ctagcctgtc
     4501 catggcctct tcgattgact gaaatacaac tacattgtca tcatttgatg tccaacctga
     4561 gcgggtaacg accgcgtatt tcctattggg gagtgcgccc atagattcaa acgtcttgcg
     4621 acccaccaga agccactgat tgtaggtcaa tgctttaaaa agtagctgct cccctttcgc
     4681 ggaccagggt atgtctggac cgcaaccaat cacgccgttt ttcgctttcg cagctatcaa
     4741 tgatactttc aaggttctca tcctgggtta acggtgcgct cttggtcgag ccgcaccggt
     4801 agctctcgtt cgacacgagc caaaagatcg agctgcggcg tactcttgtc ctcgtccggt
     4861 aagaagtcgg gattgacggc attgcgggac accacatcaa cggcgcgtcc gaacattcgc
     4921 gacagcctgc gctcaaacgg acattgatca accgataggc tgtgaacagc gccaagttgc
     4981 tgccccattg acggccacgc tttgagcaaa tccgctccag acagatcagc cgccggtact
     5041 cccggaattg ccgttatcac caagcatgca ccctcctgtt cctcctgcca gttgatgacc
     5101 tcggggcaag ccacacctcg acctttgagc caaatgaggc ggtcacgctc tccagcgagc
     5161 tcaccgcggc gggaagcagg tgcgattttc gcgaaggcat gcccgtcacc acgtcgaaaa
     5221 acaaaatcac cagattctcc gcctctgaca ggcaaccagt cagaatgcga ttcaccaaaa
     5281 aaaatattag ttcgattcaa tggaggttcc ttcagttttc tgatgaagcg cgaatataga
     5341 gaaatatccc gaatgtgcag ttaacgaatt cttgcggttt ctttcagcgc cgccaatacc
     5401 gccagcccgt cgcgcaaggg gcgcggctcg tgtgtgcgga tgaagtcagc tccacctgcg
     5461 gcggcggcaa gctctgcagc gagtgtcgcg gccccgacat cccccggacc acggcctgtg
     5521 agcgcgcgca gaaaggattt gcgcgaaaca gacagaagca ccggcaaatc gaagcgcagc
     5581 cgcaattcat cgaaccgcgc cagcaccgag agcgaggttt cgggagcagc ccccagaaaa
     5641 aaccccatgc cgggatcaag gacaaggcgg ttgcgtttga taccggcacc cgtcagcgcc
     5701 gcgatgcgcg cgtcaaagaa cgccgcaatg tgatccatga tgtcgccagc gggtgcctcg
     5761 cgccgatctg cctgcccgtc ttgcaccgaa tgcataacga cgagtttggc agatgatttc
     5821 gccaattgcg gatagaacgc agcgtctgga aaaccgcgaa tatcattgag ataggccaca
     5881 ccacgcgaca aggcataggc ttgcgtcgcg ggttgataac tgtcgagcga gacgggaatg
     5941 ccatctgcct tgagcgcgtc cagcaccggc gcgatacgcg cgatttctgt gtcggacgaa
     6001 acaggcgcgg cgtcgggatt gctggatgcc ggaccgaggt cgatcacatc tgccccctcg
     6061 gccatcagct tacgcgcctg cgcaatggct gcgtctggcg ccagataccg gcctccatcg
     6121 gagaaactgt ccgaggttat gttgacgatg ccgaaaatga tgagcgattt attcatgggg
     6181 gcttctataa taataataat cgagcatgag tctcatacgg atgctcgggt cgaaagggaa
     6241 tccccaggcg agtaacctgt ttgcggtgat ccgtttcatg atgatgtatc tgtagcattt
     6301 tggaaataaa tatatcatct ctcaataagt agatatattt atcttttttg cttctttggt
     6361 gctgcaagtc accaatacga gggaaacctg ttacggagcg gtttaaccgt aatcaacagt
     6421 gactggtgtc atgttcggaa gattaattga tagtaatcta caaaggatct tcttgagatc
     6481 cttttcaatg aatcgtaatc tcttgctctg taaacgaaaa aaccgcctgg ggaggcggtt
     6541 tgttcgaagg ttaagtcagt tggggaactg cttaacccgg taacagggtt cacgagaccg
     6601 ccattaccaa aactgttctt tcagtgtagc cgcagtcagg cctctacttc aagacctctt
     6661 aatctatctt ctcgtgcact cctgttacta atggctgctg ccagtggcgt tttgtcgtgt
     6721 ctgttccggg ttggactcaa gttgatagtt accgggacaa ggcgcagcgg tcggactgaa
     6781 cggggggttc gtgcatacag tccagcttgg agcgaactgc cttcccggaa ccgagtgtca
     6841 ggcgtggaat gagataaacg cggccataac agcggattga catcggtaaa ccgaaaggca
     6901 ggaacaggag agcgcacgag ggagccacca gggggaaacg cctggtatct ttaagtcctg
     6961 tcgggtttcg ccaccactga tttgagcgtc agatttcgtg atgcttgtca ggggggcgga
     7021 gcctatggaa aaacggcttc gccgtggcct tatctcttct ttgctaagtg tcttcctggt
     7081 atcttccagg aaatttccgc cccgtccgta agccggtacc gctcgccgca gccgaacgac
     7141 cgagcgtagc gagtcagtga gcgaggaagc ggaatatctc ctgtatcgca tattctgctg
     7201 acgcgccggt gctgcctttt ttctcctgcc acatgaagca cttcactgat tttcgcaatc
     7261 gtggcaacat agtaagccag tatacactcc gctagcgcta catgactggt tcagggctgc
     7321 gccccgaaac ccgctaacaa cctctcagct actggatatc accccatgcc atctgaatat
     7381 gatgaacaac tggattcgac tgatacgcag cttcccggcg aatatgacct ttttgattta
     7441 atggcgcagg ttactgaaga gaacctgcat gcccctgtgg attttgggtc gcctgtcggc
     7501 cgggaagcgt tatagctttt tcgcttgccc gcgtacgtgg taatactccg gtattacctt
     7561 ttatttcttt attttcatgt aattacagtg gatttttaat acccgggtat tactcgtgaa
     7621 aacgaaatat tccttttttt tcttttaatt catgcagttg cgatgaaaat cgcggctgcg
     7681 ttaggtgtat gaccattttg ggggaaccgc agaattcgga aaaaatcgta cgctaagcta
     7741 acggtgttct cgtgacagct ctttgactag gctttctaag gccattctga tagccctgac
     7801 ttcctgaaaa gccatggcta aaatttgtgc ggctaaaagg gataaccgat ggtaaagtaa
     7861 gttatccctg tcgagatact gaaaagcgtt atcctcgttt ttcccaaaac tgttttgcca
     7921 gttcgctcag agcgctagtt aactgagcga cagatttcgc actttgcaaa ttattctgcc
     7981 cggtctgtac attggtatca gcagcatcgc gtatattgat aatactgcgg tttatgtctt
     8041 cacttactgc tccctgctgc tcgaccgcag tcgctatttg cgcgttcatg tcggtaattt
     8101 cgttaacgcg ttggccaatt ccatcaagag ctgtagctgc ttcctctgcg tgagctacac
     8161 tcgtgtgcgc ttgccgacta ctttgctcca tgactgtaac agcggattgc gctcgctctt
     8221 gtagagcgct gatcatgctt tgaatatccg ttgtcgattg ctgtgtgcga gcagcaagac
     8281 tgcgaacctc atcggcgaca acagcaaaac cacgcccctg ctcaccagca cgcgcggcct
     8341 caattgctgc gttgagtgcc aacaaattcg tttgctcggc gatccctcgt ataacgtcaa
     8401 gaacttttga tatctcgtta ctttgacctt caagctcatg aataacctga gtggcttgcc
     8461 taatttcacc ttcaagggca gtgattgact ggcttgtgtg ggctaccaga cgctggccag
     8521 atgccgtctc agtgtctgct cttccggccg catctgcagc atgctgtgca ttgctcgcaa
     8581 cctcttgaat gcttgccacc atttggttta ctgccgttgc tatttgatct gtctctgcct
     8641 gctgctcaac tgtaagtaca ttgcttgact caatatcctt tagtaggcct cgggtgtgtt
     8701 cgctaagccg atttgatgca tcacctatgc gacctactat ggcgcctgtt tcagcttgca
     8761 tcattcgtaa agcaaactct atttggccaa actcatcggt gcgcccagtg tagagggatt
     8821 gacttaatgg gttattggaa atattcctgg ctctttcaac cagtcttcca agaggagaga
     8881 gaatagccaa aacactaaca gagcttaagc ttcctgacat taaagtggct aacaataagc
     8941 tgcttattga tgtatcagta agcatgccgg cagccattgc gcttgatata atactacccc
     9001 atatgagcaa gagtattttc acggaaaagc tagcagccaa tttcggcctc gcggccttcc
     9061 cgcttctcaa ttgagcatat aatttttccg cagccaaaac ctgctcaggt tcaggcttgg
     9121 tccttacaga ctggtattca acaatcgaac cattcttagc tattggcgtt acataagcac
     9181 ttacccaata gtggtcgcca tttttacagc gattttttac tagccccatc catgagcggc
     9241 cagattttaa tgtactccac atatgctcaa atgcagcagg cggcatatct gggtgtctta
     9301 cgatgttgtg aggctggcct aatagttctt cctcagtgaa accactgatt ttaatgaagt
     9361 caggattaac gtacgtgata tggctttgag gggaggtagt cgaaagaata ttggcatctt
     9421 ttgggagttc taagtttcga cccgtcactg gtaaattctg gcgcataaga acctcaaggg
     9481 ttggctgttt tattttattg ttttcggcat taagcccaat ttcttgagcg ttacgataaa
     9541 gctagcatgg aaacgatagg tgcaagcaag ttaagggttg catcgcgcat gtcaatctag
     9601 gctataccct aacttgatgt caggcagggc cgcgccgctt cgtcagaata gagtctgctt
     9661 tcccattttt tgacacatgc ccgcgaaggt tatagatttc agcctgacag aaatgggctt
     9721 tgaggcacaa cggaacagaa agtgcactta agccgccttc aaccaaggag acatcgtgca
     9781 ggggcaccgc atcggctacg tccgggtcag cagctttgac cagaacccgg aacgccagct
     9841 ggaacaaacc caggtgagca aggtgttcac cgacaaggca tcgggcaagg acacccagcg
     9901 cccccagctc gaagcgctgc tgagcttcgt ccgcgaaggc gatacagtgg tggtgcacag
     9961 catggatcgg ctggcccgca acctcgatga cctgcgtcgc ttggtacaga agctgactca
    10021 gcgcggcgtg cgcatcgagt tcctgaagga gggcctggtg ttcactggcg aggactcgcc
    10081 gatggccaac ctgatgctgt cggtgatggg ggccttcgct gagttcgagc gcgccctgat
    10141 ccgcgagcgg cagcgtgagg gcatcgcctt ggccaagcag cgtggcgcgt accggggccg
    10201 caagaaagcc ctgtccgatg agcaggctgc taccctgcgg cagcgagcga cggccggcga
    10261 gcccaaggcg cagcttgccc gcgagttcaa catcagccgg gaaaccctct accagtacct
    10321 ccgcacggac gactgacaca tgccgcgtcg cttgatcctc tcggccacgg agcgggacac
    10381 cctgcttgcg ctgccggaaa gccaggatga cctgatccgc tactacacct tcaacgactc
    10441 cgacctgtcg ctgatccgcc agcgacgcgg cgacgccaac cgcctcggct tcgccgtgca
    10501 gctctgcctg ctgcgctacc ccggttacgc gctgggaacc gacagcgagc tgcccgagcc
    10561 ggtcatcctg tgggtggcga agcaagtcca ggccgagccg gcgagctggg caaagtacgg
    10621 cgagcgcgac gtgacccgtc gcgagcatgc ccaggaactg cgcacctacc tgcaactggc
    10681 cccgttcggc ctgtccgact tccgcgccct ggtgcgcgag ctaaccgagc tggcccagca
    10741 gaccgacaaa ggcttgctgc tggccggtca ggccctggag agcctacggc agaaacgacg
    10801 catcctgccg gcgctgagcg tgattgaccg ggcctgctcg gaagccattg cgcgagccaa
    10861 tcggcgggtc taccgcgccc tggtcgaacc actcacggac tcgcatcggg ccaagctgga
    10921 cgagctgttg aagctcaagg ccggcagcag catcacctgg ttgacctggc tgcgccaggc
    10981 accgctgaaa cccaactctc ggcacatgct ggaacacatc gagcggctga agacatttca
    11041 gttggtggac ttgcccgaag gcctgggccg gcacatccac cagaaccgcc tgctcaagct
    11101 ggcccgcgag ggtgggcaga tgacgcccaa agacctcggt aagttcgagc cgcagcgccg
    11161 ctacgcgacc ctggccgccg tggtgctgga gagcaccgcg accgtgatcg atgagctggt
    11221 cgatctgcat gaccgcatcc tggtcaagct gttcagcggc gcgaagcaca agcatcagca
    11281 gcagttccag aagcagggca aggcgatcaa cgacaaggtg cgcctgtact ccaggatcgg
    11341 ccaggcgctg ctggaagcga aggaaagcgg cagcgacccc tatgccgcca tcgaggcggt
    11401 gattccctgg gacgagttca ccgagagcgt cagcgaggcc gagctgctgg cccggccgga
    11461 aggcttcgac cacctgcacc tggtcggcga gaacttcgcc accctgcgcc gttacacgcc
    11521 ggccttgctg gaggtgctgg aactgcgcgc cgcgccggcc gcgcaaggcg tgctggcagc
    11581 cgtgcagacc ctgcgtgaga tgaacgccga caacctgcgc aaggtgccgg ccgatgcacc
    11641 cacggccttc atcaagccgc gctggaagcc gctggtgatc accccggaag gcctcgaccg
    11701 gaaattctac gaaatctgcg ccctgtccga gctgaagaac gccctgcgct ccggcgacat
    11761 ctgggtcaag ggctcgcggc agttccgcga cttcgacgac tacctgctgc cggccgagaa
    11821 gttcgccgca ctcaagcgcg agcaggccct gcccctggcg atcaacccga acagcgacca
    11881 gtacctggaa gagcgtttgc agctgctgga cgagcagttg gccaccgtca cccgcctggc
    11941 caaggacaac gagctgcccg atgccatcct caccgagtca gggctgaaaa tcaccccgct
    12001 ggatgcggcg gtgccggatc gggcgcaggc gctgatcgac caaaccagcc agttactgcc
    12061 gcgcatcaag atcaccgaac tgctgatgga cgtggacgac tggacgggct tcagccgcca
    12121 cttcacccac ttgaaggacg gggccgaggc caaagacagg acgttgctgc tgtccgcaat
    12181 cctcggtgat gcgatcaacc tcgggctgac caagatggcc gagtcgagcc ccggcctgac
    12241 ctacgccaag ctgtcctggc tgcaagcctg gcacatccgc gacgaaacct attcggcggc
    12301 cttggccgag ctggtcaacc accagtatcg ccacgccttt gccgcccact ggggcgacgg
    12361 cacgacctca tcctccgatg gccagcgctt ccgcgcgggt ggccggggcg agagcaccgg
    12421 gcacgtcaac ccgaagtacg gtagcgagcc gggacggctg ttctataccc atatctccga
    12481 ccagtacgcg ccgttcagca cccgcgtggt gaatgtcggc gtccgcgatt ccacctatgt
    12541 gctcgacggc ctgctgtacc acgagtccga cctgcggatc gaggagcact acaccgacac
    12601 ggccggcttc accgatcacg tctttgccct gatgcacctg ctaggcttcc gcttcgcgcc
    12661 gcgcatccgc gacctcggcg aaaccaagct gtacgtgccg cagggcgtgc aagcctaccc
    12721 gacgttgcgc ccgctgatcg gcggcaccct gaacatcaag cacgtgcgtg cccactggga
    12781 cgacatcctg cgcctggcca gctcgatcaa gcagggcacc gtcaccgcct cgctgatgct
    12841 gcgcaagctc ggcagctacc cgcgccagaa cggactggcc gtggccctgc gcgagctggg
    12901 ccggatcgag cgcacgctgt tcatcctgga ctggctgcaa agtgttgaac tgcgccgccg
    12961 cgtgcatgcc ggcctgaaca aaggtgaggc gcgcaactcg ctggccaggg cggtgttctt
    13021 caaccgcctt ggggaaatca gggatcggag cttcgagcag cagcgctacc gggccagcgg
    13081 cctcaacctg gtgacggcgg ctatcgtgct gtggaacacg gtgtacctgg aacgcgccac
    13141 ccaggggttg gtcgaggccg gcaagccggt ggacggcgag ctgctgcaat tcctgtcgcc
    13201 gctgggctgg gagcacatca acctaaccgg cgattacgtc tggcggcaga gccgcagact
    13261 ggaagacggg aagtttcggc ccttacggat gcccggaaaa ccttagcgta cgattttttc
    13321 cgaattctgc gggctcccct atctcatctg cgcaaggcag aacgtgaaga cggccgccct
    13381 ggacctcgcc cgcgagcgcc aggcgcacga ggccggcgcg cggacccgcg ccacggccca
    13441 cgagcggacg ccgcagcagg agcgccagaa ggccgccaga gaggccgagc gcggccgtga
    13501 ggcttggacg ctagggcagg gcatgaaaaa gcccgtagcg ggctgctacg ggcgtctgac
    13561 gcggtggaaa gggggagggg atgttgtcta catggctctg ctgtagtgag tgggttgcgc
    13621 tccggcagcg gtcctgatca atcgtcaccc tttctcggtc cttcaacgtt cctgacaacg
    13681 agcctccttt tcgccaatcc atcgacaatc accgcgagtc cctgctcgaa cgctgcgtcc
    13741 ggaccggctt cgtcgaaggc gtctatcgcg gcccgcaaca gcggcgagag cggagcctgt
    13801 tcaacggtgc cgccgcgctc gccggcatcg ctgtcgccgg cctgctcctc aagcacggcc
    13861 ccaacagtga agtagctgat tgtcatcagc gcattgacgg cgtccccggc cgaaaaaccc
    13921 gcctcgcaga ggaagcgaag ctgcgcgtcg gccgtttcca tctgcggtgc gcccggtcgc
    13981 gtgccggcat ggatgcgcgc gccatcgcgg taggcgagca gcgcctgcct gaagctgcgg
    14041 gcattcccga tcagaaatga gcgccagtcg tcgtcggctc tcggcaccga atgcgtatga
    14101 ttctccgcca gcatggcttc ggccagtgcg tcgagcagcg cccgcttgtt cctgaagtgc
    14161 cagtaaagcg ccggctgctg aacccccaac cgttccgcca gtttgcgtgt cgtcagaccg
    14221 tctacgccga cctcgttcaa caggtccagg gcggcacgga tcactgtatt cggctgcaac
    14281 tttgtcatgc ttgacacttt atcactgata aacataatat gtccaccaac ttatcagtga
    14341 taaagaatcc gcgcgttcaa tcggaccagc ggaggctggt ccggaggcca gacgtgaaac
    14401 ccaacagacc cctgatcgta attctgagca ctgtcgcgct cgacgctgtc ggcatcggcc
    14461 tgattatgcc ggtgctgccg ggcctcctgc gcgatctggt tcactcgaac gacgtcaccg
    14521 cccactatgg cattctgctg gcgctgtatg cgttgatgca atttgcctgc gcacctgtgc
    14581 tgggcgcgct gtcggatcgt ttcgggcggc ggccggtctt gctcgtctcg ctggccggcg
    14641 ctgctgtcga ctacgccatc atggcgacgg cgcctttcct ttgggttctc tatatcgggc
    14701 ggatcgtggc cggcatcacc ggggcgactg gggcggtagc cggcgcttat attgccgata
    14761 tcactgatgg cgatgagcgc gcgcggcact tcggcttcat gagcgcctgt ttcgggttcg
    14821 ggatggtcgc gggacctgtg ctcggtgggc tgatgggcgg tttctccccc cacgctccgt
    14881 tcttcgccgc ggcagccttg aacggcctca atttcctgac gggctgtttc cttttgccgg
    14941 agtcgcacaa aggcgaacgc cggccgttac gccgggaggc tctcaacccg ctcgcttcgt
    15001 tccggtgggc ccggggcatg accgtcgtcg ccgccctgat ggcggtcttc ttcatcatgc
    15061 aacttgtcgg acaggtgccg gccgcgcttt gggtcatttt cggcgaggat cgctttcact
    15121 gggacgcgac cacgatcggc atttcgcttg ccgcatttgg cattctgcat tcactcgccc
    15181 aggcaatgat caccggccct gtagccgccc ggctcggcga aaggcgggca ctcatgctcg
    15241 gaatgattgc cgacggcaca ggctacatcc tgcttgcctt cgcgacacgg ggatggatgg
    15301 cgttcccgat catggtcctg cttgcttcgg gtggcatcgg aatgccggcg ctgcaagcaa
    15361 tgttgtccag gcaggtggat gaggaacgtc aggggcagct gcaaggctca ctggcggcgc
    15421 tcaccagcct gacctcgatc gtcggacccc tcctcttcac ggcgatctat gcggcttcta
    15481 taacaacgtg gaacgggtgg gcatggattg caggcgctgc cctctacttg ctctgcctgc
    15541 cggcgctgcg tcgcgggctt tggagcggcg cagggcaacg agccgatcgc tgatcgtgga
    15601 aacgataggc ctatgccatg cgggtcaagg cgacttccgg caagctatac gcgccctagg
    15661 agtgcggttg gaacgttggc ccagccagat actcccgatc acgagcagga cgccgatgat
    15721 ttgaagcgca ctcagcgtct gatccaagaa caaccatcct agcaacacgg cggtccccgg
    15781 gctgagaaag cccagtaagg aaacaactgt aggttcgagt cgcgagatcc cccggaacca
    15841 aaggaagtag gttaaacccg ctccgatcag gccgagccac gccaggccga gaacattggt
    15901 tcctgtaggc atcgggattg gcggatcaaa cactaaagct actggaacga gcagaagtcc
    15961 tccggccgcc agttgccagg cggtaaaggt gagcagaggc acgggaggtt gccacttgcg
    16021 ggtcagcacg gttccgaacg ccatggaaac cgcccccgcc aggcccgctg cgacgccgac
    16081 aggatctagc gctgcgtttg gtgtcaacac caacagcgcc acgcccgcag ttccgcaaat
    16141 agcccccagg accgccatca atcgtatcgg gctacctagc agagcggcag agatgaacac
    16201 gaccatcagc ggctgcacag cgcctaccgt cgccgcgacc ccgcccggca ggcggtagac
    16261 cgaaataaac aacaagctcc agaatagcga aatattaagt gcgccgagga tgaagatgcg
    16321 catccaccag attcccgttg gaatctgtcg gacgatcatc acgagcaata aacccgccgg
    16381 caacgcccgc agcatcgcga ccgtcatcgg tgagaagttc ggcaggtatt gggtggtgac
    16441 aatgtaggtg ctgccccaaa tggcaggtgc tatcgctgtg aacaataaat cgggcgtgcg
    16501 taatgacatg cgattacaag acctccgcta cggcgatggg tttttgagag ttgcaggcgc
    16561 cgcgatgacc gcaccctgac ttggactggc cctgcctcgc accaatccac ctgcggctat
    16621 ggccgcgatc atgcgaggcc cgaaaattac acgacctgta cacgtccgcc gaacccggaa
    16681 cgcaacagag cttcgtgggc atcccgatcc gggtcgtagc agcagtcctg gaccaaacgc
    16741 acgtcgtagt ccgcatcact agcccaggcg acgcttgaaa gaacaacgcc ggtggtgctt
    16801 atcccggcca tgacaagcgt gcttacgccg cgcgtccgaa ggtcggcgtc gagcgccgtg
    16861 ccataaaaga cgctggctcg cggacatgca tagaaaaggt cgccccgttc gatcgcaagc
    16921 ccttcgacgg gcagaccggt gcgaaatcgt ccgctcggga gatacggtga gatttggcga
    16981 ttcgtcgccg gcggcgcatg ttcatactct tcgccgagcg aaaagttggg gaacagcacg
    17041 ggccggccgc gcaaggcgtg ctggcagtcg tgcagaccct gcgtgagatg aacgccgaca
    17101 acctgcgcaa ggtgccggcc gatgcaccca cggccttcat caagccgcgc tggaagccgc
    17161 tggtgatcac cccggaaggc ctcgaccgga aattctacga aatctgcgcc ctgtccgagc
    17221 tgaagaacgc cctgcgctcc ggcgacatct gggtcaaggg ctcgcggcag ttccgcgact
    17281 tcgacgacta cctgctgccg gccgagaagt tcgccgcact caagcgcgag caggccctgc
    17341 ccctggcgat caacccgaac agcgaccagt acctggaaga gcgtttgcag ctgctggacg
    17401 agcagttggc caccgtcacc cgcctggcca aggacaacga gctgcccgat gccatcctca
    17461 ccgagtcagg gctgaaaatc accccgctgg atgcggcggt gccggatcgg gcgcaggcgc
    17521 tgatcgacca aaccagccag ttactgccgc gcatcaagat caccgaactg ctgatggacg
    17581 tggacgactg gacgggcttc agccgccact tcacccactt gaaggacggg gccgaggcca
    17641 aagacaggac gttgctgctg tccgcaatcc tcggtgatgc gatcaacctc gggctgacca
    17701 agatggccga gtcgagcccc ggcctgacct acgccaagct gtcctggctg caagcctggc
    17761 acatccgcga cgaaacctat tcggcggcct tggccgagct ggtcaaccac cagtatcgcc
    17821 acgcctttgc cgcccactgg ggcgacggca cgacctcatc ctccgatggc cagcgcttcc
    17881 gcgcgggtgg ccggggcgag agcaccgggc acgtcaaccc gaag
//
