LOCUS       NZ_CP036441            19305 bp    DNA     circular CON 08-JAN-2024
DEFINITION  Klebsiella pneumoniae strain ABFQB plasmid pKPC-5fbf, complete
            sequence.
ACCESSION   NZ_CP036441
VERSION     NZ_CP036441.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN03455995
            Assembly: GCF_004322995.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 19305)
  AUTHORS   Conlan,S., Thomas,P.J., Mullikin,J., Palmore,T.N., Frank,K.M. and
            Segre,J.A.
  TITLE     Whole genome sequencing of Klebsiella pneumoniae ABFQB
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19305)
  AUTHORS   Segre,J.A. and Mullikin,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2019) NIH Intramural Sequencing Center, 5625
            Fishers Lane, Rockville, MD 20852, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Coverage                   :: 110x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/08/2024 04:29:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,335
            CDSs (total)                      :: 5,216
            Genes (coding)                    :: 5,117
            CDSs (with protein)               :: 5,117
            Genes (RNA)                       :: 119
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 44 of 99
            Pseudo Genes (incomplete)         :: 54 of 99
            Pseudo Genes (internal stop)      :: 12 of 99
            Pseudo Genes (multiple problems)  :: 11 of 99
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036441.1.
            Bacteria and source DNA available from Karen Frank, Department of
            Laboratory Medicine, National Institutes of Health Clinical Center.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19305
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="ABFQB"
                     /db_xref="taxon:573"
                     /plasmid="pKPC-5fbf"
                     /geo_loc_name="USA"
                     /lat_lon="38.984652 N 77.094709 W"
                     /collection_date="2015"
     gene            join(18912..19305,1..26)
                     /locus_tag="WN11_RS27090"
     CDS             join(18912..19305,1..26)
                     /locus_tag="WN11_RS27090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            332..595
                     /locus_tag="WN11_RS27095"
                     /old_locus_tag="WN11_27235"
     CDS             332..595
                     /locus_tag="WN11_RS27095"
                     /old_locus_tag="WN11_27235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            585..884
                     /locus_tag="WN11_RS27100"
                     /old_locus_tag="WN11_27240"
     CDS             585..884
                     /locus_tag="WN11_RS27100"
                     /old_locus_tag="WN11_27240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(946..1323)
                     /locus_tag="WN11_RS27105"
                     /old_locus_tag="WN11_27245"
     CDS             complement(946..1323)
                     /locus_tag="WN11_RS27105"
                     /old_locus_tag="WN11_27245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            1392..1571
                     /locus_tag="WN11_RS27110"
                     /old_locus_tag="WN11_27250"
     CDS             1392..1571
                     /locus_tag="WN11_RS27110"
                     /old_locus_tag="WN11_27250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(1599..2129)
                     /locus_tag="WN11_RS27115"
                     /old_locus_tag="WN11_27255"
     CDS             complement(1599..2129)
                     /locus_tag="WN11_RS27115"
                     /old_locus_tag="WN11_27255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(2136..2867)
                     /locus_tag="WN11_RS27120"
                     /old_locus_tag="WN11_27260"
     CDS             complement(2136..2867)
                     /locus_tag="WN11_RS27120"
                     /old_locus_tag="WN11_27260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(2867..4462)
                     /locus_tag="WN11_RS27125"
                     /old_locus_tag="WN11_27265"
     CDS             complement(2867..4462)
                     /locus_tag="WN11_RS27125"
                     /old_locus_tag="WN11_27265"
                     /inference="COORDINATES: protein motif:HMM:NF024108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_032423802.1"
                     /translation="MFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLAVGIVL
                     ARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNALADFS
                     SEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRCVRDFG
                     DAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLIAGLNL
                     GETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLITRLENV
                     ADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARDEFREW
                     PHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFVKTTVL
                     DNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQKEARPL
                     FDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEFRPPAD
                     GGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            4840..6159
                     /locus_tag="WN11_RS27130"
                     /old_locus_tag="WN11_27270"
     CDS             4840..6159
                     /locus_tag="WN11_RS27130"
                     /old_locus_tag="WN11_27270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISKpn6 family transposase"
                     /protein_id="WP_004152397.1"
                     /translation="MAASYLPYRPDQSYLLPPSLGEWLPEGHLAYFISETVDTLDLSAF
                     HARYAGGGPGNQPFHPAMMVKVLIYGYASGVFSSRKLARKLYEDVALRVLAAGNFPAHR
                     TLSDFRALHLTELENLFVQVVQLARECGLVKLGTIAVDGTKVKANASRHKAMSYKRMKP
                     AEDELHCEIKALLDRAKATDDQERNEPELDIPAEISRREKRLEAIQAAKARLEARQREA
                     DQARGRSEDDGRRPRHPDGSDKGGGSYKREFGVPDDRDQESFTDPDSRIMKHAGGGSEQ
                     SYNGYTAVDAEHQIIVAAELTNCAADSQALLGMLAAVQANTGEMPAQTLADAGFRSEAV
                     LAKVADHHGDVIVALGREGREDAKVNAKTHPHTAAIAAKLKTEQGDAAYRRRKSIVEAP
                     NGWIKAVMGLRQFSMRGLDKVQAEWKLVCMALNLRRMAYL"
                     /name="IS1182-like element ISKpn6 family transposase"
     gene            complement(6409..7290)
                     /locus_tag="WN11_RS27135"
                     /old_locus_tag="WN11_27275"
     CDS             complement(6409..7290)
                     /locus_tag="WN11_RS27135"
                     /old_locus_tag="WN11_27275"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015256839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-3"
                     /protein_id="WP_004152396.1"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIG
                     VYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
                     SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
                     WELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRA
                     AVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKYSEAVIAAAA
                     RLALEGLGVNGQ"
                     /name="carbapenem-hydrolyzing class A beta-lactamase KPC-3"
     gene            complement(7677..8456)
                     /gene="istB"
                     /locus_tag="WN11_RS27145"
                     /old_locus_tag="WN11_27285"
     CDS             complement(7677..8456)
                     /gene="istB"
                     /locus_tag="WN11_RS27145"
                     /old_locus_tag="WN11_27285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISKpn7 family helper ATPase
                     IstB"
                     /protein_id="WP_004152394.1"
                     /translation="MNLQHERIDALCQQLKLERVATHYPVLAQQAVREDFSFTDFLEHL
                     LRHEAGCRQQRSRELLTRMACFPGIKTLEDYDFSFNPGVPKALVQELGSLAFVERAENV
                     VLIGPSGIGKTHLAIALGYKAAQAGVKTRFITAADLMLQLSTAQRQGRLKEYFNRAILG
                     PRLLVIDEIGYLPFGREEANLFFQVVAKRYEKGAMILTSNLPFSQWADAFAGDTTLTAA
                     MLDRLLHHAHILTLSGESYRLKDKRKAGVVRKNSKPE"
                     /name="istB"
     gene            complement(8453..9478)
                     /gene="istA"
                     /locus_tag="WN11_RS27150"
                     /old_locus_tag="WN11_27290"
     CDS             complement(8453..9478)
                     /gene="istA"
                     /locus_tag="WN11_RS27150"
                     /old_locus_tag="WN11_27290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490293.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="WP_004199214.1"
                     /translation="MLTQEQTVEIRVLARQGHSIRHIARTLGVSRNTVRRYLRDPSVAR
                     YQPREPRPTKLGPFESYLRQRVEQAHPIWLPATVLNREIRAQGYGGGLSLLRAFLATLK
                     PARREAGPAVRFETEPGRQLQADFVVLRRARSPMSAFVATLGYSRMTFVTFVPDESFES
                     VRDSLLLAFDYLGGVPREVLFDNMKTVVLERDAYGDGKHRFHPGLLQLADDLGFRIRLC
                     RPYRAQTKGKVERFNRYFRESFYNPLLTRMKGTGLLLDCAAANRRVRDWLADEANVRVH
                     ATLNERPIDRWRQEREHLQPLPSRVRRDEAPLLDNSLRPVPLESLQHPLSVYDAIGEAC
                     R"
                     /name="istA"
     gene            complement(9585..12614)
                     /gene="tnpA"
                     /locus_tag="WN11_RS27155"
                     /old_locus_tag="WN11_27295"
     CDS             complement(9585..12614)
                     /gene="tnpA"
                     /locus_tag="WN11_RS27155"
                     /old_locus_tag="WN11_27295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152392.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family transposase"
                     /protein_id="WP_004152392.1"
                     /translation="MSKKNKLLSVLSDAEQEALYGLPEFDDAQQLEYLAVTETELALAN
                     SRPSLHAKVYCLLQIGYFKAKHAFFSFDWDEVEDDCAFVLSRYFHGEVFEPKAITKHER
                     YTQREQIAKLFGYWPWSAAFLPQLEQQAARTVRRDVTPGFVAAELIVWLNEHKIIRPGY
                     TTLQELVSETLSAERRRLGNLLEQALDESAKAALSQLLVRDDTLSQLAALKQDAKNFGW
                     RQMVREREKRATLEPLHAIAKTLLPKLDVSQQNLLYYASLANFYTVHDLRNLKADQTQL
                     YLLCYAWVRYRQLSDNLVDAMAYHMKQLEDESSAGAKQSFADEQVRRQQETPRVGRLLS
                     LYVDDSVADPTPFGEVRQRAYKIMPRDTLQTTAQRMSVKPASKLALQWQAVDGLADRMR
                     RHLRPLYVALDLSGSNPDSPWLAALAWAKGVFAKQQRLSQRPLDEWPAATLPKRLRPYL
                     LTFDADGKPTGLHADRYEFWLYRQIRKRLQSGELYLDDSLQHRHFSDELVEMDRKIDVL
                     AKMEIPFLQQPVHAQLDALTAELRTQWLAFNRELKQGKLTHLEYNKDTQKLTWRKPKSE
                     NEKAREKAFYEKLPFCDVADVFRFVNDECKFLSAFTPMQPRYAKKVADADSLMAVIIAQ
                     AMNHGNHVMARTSDIPYHVLDSGYQQYLRQATLHAANDCISNAIATLPIFPYYSFDLET
                     LYGAVDGQKFSVERPTVKARYSRKYFGRGKGVVAYTLLCNHIPLNGYLIGAHDYEAHHV
                     FDIWYRNTSDIMPTAITGDMHSVNKANFAILHWFGRRFEPRFTDLNAQLKELYCADDPA
                     QYQACLIRPVGKIDCDLIHREKPNIDRIVATLGLKEMTQGTLIRKLCTYTTTNPTRRAI
                     FEFDKLIRSIYTLRYLRDPQLERNVHRSQNRLESYHQLRSAIAQVGGKKELTGRTDIEI
                     EISNQCARLIANTIIFYNSAILSRLVTKYEAAGNSKALALITKISPAAWRHILLNGHYT
                     FQSSGKTIDLDAIVAGLELE"
                     /name="tnpA"
     gene            12724..14439
                     /gene="tnpR"
                     /locus_tag="WN11_RS27160"
                     /old_locus_tag="WN11_27300"
     CDS             12724..14439
                     /gene="tnpR"
                     /locus_tag="WN11_RS27160"
                     /old_locus_tag="WN11_27300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family resolvase TnpR"
                     /protein_id="WP_004152391.1"
                     /translation="MKTGQTTASSSTPVGFPDADSLAALRGWYAGLSSRAAVEHYLAAR
                     KAAGQSARGMLGHIRRQLIVFANSRHRPDLADVFQHAPEERQGRAGAVERAIRLLPTLP
                     APKPQISDSIDQWLSPRTVRALQAYGIHTLSALTVRIPRRRGWWKAIEGLGMTGARQVE
                     AFFAAHPQLTERARALIPIIQPSGIVPWEQLRLPNEVDGSQGNFRAPRNACTLNATNDY
                     EAVQAWLALHETVATQRAYRKEAARLILWAIVERGRALSSLTTDDAIAYRAFVRHPTPR
                     ERWVGPPRPRDSVEWRPFSGGLSARSAAYALTVLSALFRWLIEQRYVLANPFAGVKVRG
                     HALRPALDTARGFTEGEWLLLRAIADGLEWSYGWSEPAAQRLRFMLDFGYATGLRASEL
                     VGAVLGNVRLDEHGDHWLHLVGKGGKPGKVALPPLAYTALDQYLAQRQLPVSRERWNPK
                     TPLVGSLGEDGNAGITGPHLWCVLRRFFTQAAEAIEADHPVAAEKLRRATPHWMRHSHA
                     SHALARGAQLTAVRDNLRHASIATTSMYLHGDELERARQMRQAFGARHVKRGVD"
                     /name="tnpR"
     gene            complement(14447..14842)
                     /locus_tag="WN11_RS27165"
     CDS             complement(14447..14842)
                     /locus_tag="WN11_RS27165"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228716160.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGVLSGNPRKFRHSV"
                     /name="hypothetical protein"
     gene            complement(16323..16472)
                     /locus_tag="WN11_RS27175"
                     /old_locus_tag="WN11_27315"
     CDS             complement(16323..16472)
                     /locus_tag="WN11_RS27175"
                     /old_locus_tag="WN11_27315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(16557..16814)
                     /locus_tag="WN11_RS27180"
                     /old_locus_tag="WN11_27320"
     CDS             complement(16557..16814)
                     /locus_tag="WN11_RS27180"
                     /old_locus_tag="WN11_27320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(16824..18509)
                     /locus_tag="WN11_RS27185"
                     /old_locus_tag="WN11_27325"
     CDS             complement(16824..18509)
                     /locus_tag="WN11_RS27185"
                     /old_locus_tag="WN11_27325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     ARG             complement(6413..7290)
                     /name="blaKPC-3"
                     /gene="blaKPC-3"
                     /gene_name="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-3"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     BGC             11824..19305
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          15642..16220
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2140..2867)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.35e-150"
ORIGIN
        1 tcgatggcta tgaaggcaga cagtaagtgg atttaccata acgcgtcatt acgcgcaccg
       61 ctcagacggg ctcagggcgt ttccggcggc tacgggataa aacaggcaac aacccccccg
      121 gaaaactgcc ggaaacgcgc ccgataaatt ttatcctaat gcatgcctat gcacgcaact
      181 gcatggcata tgttttgacg taaaatggat gccgtaagcc cttttttacc gactttctgc
      241 ttcatcagcc tgactgacac gaccatattc tttcagaccg ccccctgcta aacttccttc
      301 atattgccgc attaacccgg gaggctccgc aatgagcaac actacacact acgaaaacgc
      361 caactttctt cgggaactgg ctgaaagcct gccccgcata ctgccggaag gtggcccgga
      421 caaagctgcg ctgttgcagc gactggctaa cgaagaactg gcccaggcag agtatgaaga
      481 tcaggttcgc gccaaagtga ccgccgcccg tgctgacacg cgtccgggta tgaccacgga
      541 acaactccgc cagcgcctgc atggccgtta tcaggaactg cgcgatgccg tatgacgtgg
      601 aatggaagca gggagccatc gaggatgtaa cgacgctgtt tgactatatc gcggaaaatt
      661 catccctgtg ggatgcgcag aacgttaccg accgggttct cgctgcggcg gacaaactgg
      721 ccgacttccc gcgactctat gaagtggact cacgctatgg cgaggacgtt cgccggatca
      781 gtctgatggg acagcatgtc ctctatgatg ttgatgacca gaccagaaaa gtccgggttc
      841 tggccgtggt cggccagcgc cagaatcccc atattgttct ctaataaccg gtgacgggga
      901 cgcaattcat tgcgtggccg tcgccggttg gacaagcaca gcgcgtcagc gttttcccca
      961 cggccaccac cggcgcggtg ttccggccgg ggtctctgct gtctccggtt tgtgttccag
     1021 cagtctcatg gactgcattt cctgccgtag cccggccacc tcctccctga gtgcttttat
     1081 ctccgcgatc aacgcgtcgg aggccatttt ttcagtctca cccgacagtc tcaactcgtc
     1141 ccgctcgtga gtctcatcct gtcttaactc accgtacacc cggataagct cgctggtatc
     1201 caccacccgg ccgccatcag cttccgtacg gtatgatacg cggcctttcg ccatatcccg
     1261 atacagggaa cttcgggctt tacccgtcag ttccgtcgcc tgtctcaccg tcacccacgc
     1321 cattgtctca ccccgctatt tttgagacag tatacctgac aggcgcacac catgcccgga
     1381 aggaaagaat catgacaaaa caggaaaaaa cagccctcaa tatggctaaa tttattaagg
     1441 agcagtcgct gctattgctc gataaactga atgagctgga tatggatacc ccggccgaca
     1501 tgtgcgagcg gctacacgag gatgcggaaa cactctggca ggtgatgcgg gataagctcg
     1561 gggaggaata acagcaccgg catggccggt gctggcattt attttttgcc gaacggccac
     1621 caccggcggg caggtttgtc ctccggcagt tcaggtaccg gcacgttaaa atagcggctg
     1681 ttatattccc gcatcagctc cgctttcagc ttctcgttca ccgcgctttc cccgtgccgc
     1741 tcactcacca cgtcaatcat cgcgttaatc tgctccggtg agcacttccc ggcatcaacc
     1801 acctgcacac cgttctcgat ggcgaaccgc tccaccttgc gatagaggta atcacacagc
     1861 ttcattcctg tgggtttgtt ccgttcccat tgcggatttt taccagtgaa aaagtacgtg
     1921 gctttttcgt cgctgttgag ccgctcgtca tacatcccga tggatttcat catcgccaga
     1981 tgctgggccc ggtcgacaaa acagaaaaca tacgccccgg tctgccaggc gagcaccacc
     2041 atatcttcca gatgctcgct ggtcggcatg atgcagcgct cgccgttccg gtcctccgcg
     2101 tcttcaataa ataccatgta cagcgccata atccctcact ccgttgtcat aaatttaaag
     2161 cacgcaaaca accgttcacg atccagctct gccgttttgc gggcctcgcc ggtctgtggg
     2221 ttcacgattt catccaccga caggattgcc cgctgcaccc tgacctgcgt cgcccggtcc
     2281 gggcagatgt accagatttc atcgatgccg ttagctttgc ggttgaacag atacccggac
     2341 accacttcct gataccggcg acggctcttg acggtgcgct ccacctcaaa cgccaccgtt
     2401 ttaccgtcca gctccgccag ggcgtccggc actttcatgc ctttaagact cagacggtgc
     2461 agaatgcgcc agccggtggc ccctctggct tccatatcaa ggcgcaggga ttgcacggcc
     2521 agccggtgcg gcagatgtgc tgccgacacc cttgacggct gaaacggaat aacatccgcc
     2581 agcggttcgt cctcgtcgaa cgagaacgcc acgccatgcg gcgtcagccc ccacacgctg
     2641 acctgacggc cgtccaccgg atatttggtc cggaccagca gccctttcgc caccaggctg
     2701 tcgaggaagc ggtagaccgg ctgcaccgcc gcaatcccca gccgccgcgc aaccagctcc
     2761 gccgtggaac acagctcttc ccgcaaccag cgcagggtca gccgggtttt ctccgcgttc
     2821 cgcgcctgtc gtttcgcgtg gctgacgttg tacagctcca gcgccatcag taaatccccg
     2881 caaaatcatc atccgctttc ggcccgccgc cgtcggccgg gggccggaac tccgccaggg
     2941 gatcggtttt cgccagcacc gggaaacgct gcaacgggat ttcccggcgc tcaacccgca
     3001 gcggactgct gaacgccatc cgggccacac ccagcccggt catgaccgcg aacccgtccg
     3061 gcaggtgttg cagggtgttc acgtcaaaca gcggccgcgc ctccttctgg atgaagctgt
     3121 ccccgctgat atgctccacg ttccccgcct cccggctggc acggcggcgc tccacgtcca
     3181 ccctgatttc cccggtctgc cccgccgccc actgcgcgga ctccaggctg gccgcccggt
     3241 aaaaccagcg gatcggcgtg ttatccagta ccgtggtttt cacaaattca gcgggcagat
     3301 cctgcccgca ctgcccgaaa tcgcccagcg actggtgcgc gagcaacaga ttgcagtccc
     3361 ggctgcgcag cgtccccagt gcgttcagta catacttcga cagcagatat ttaatttcat
     3421 cgagcatcac gctgacgtgt ggccactccc ggaactcgtc ccgcgcaatg atgatttgcg
     3481 cgcagcgggc aaacagcatt ttttgcacac ggatcaccgc ctcgtcgtcc atcgagccga
     3541 taacgtacag gcagccgccg ccgttgataa tccccgccac atcgatgcca ctgtccgtct
     3601 gcaggacgct caggtcagcg acgttttcca gcctagtgat caaccccttc acgtcctttt
     3661 tcagggcctc cggcagcgcg tacgccgccg ccagcacctg ctgaatgttt gccccctgcg
     3721 gaaactgctc cgcaatcagc ttcgccgctt tctgctcgct gatgcggtag tggtccgcca
     3781 cgtcgccggt ctcgcccagg ttaagcccgg caatcagcag gtttttcagc gcgtactggt
     3841 cgagatcgcg gaacagattc agctgcgccg gtttccccgg ccgcagatcc agcagggtga
     3901 agtccggaca gtgcgcccgg aagacgtgcg gcgcccatgc gtcccctttg gggtcgaagt
     3961 acaccaccgc gtccccgaaa tcgcgtacgc agcgaatgag cgcgttggtg gccatcacgc
     4021 tcttgccgct cccgggcagg ccgaggatct gaatgttggt cttgcgccag gtatcacgcg
     4081 gaaccagcac cggcttgccc tgctcatcct tacccagaaa caccgcctgc tcctgccggg
     4141 cctgctccga ggaaaaatcg gccagcgcat taaccggtac cggctccccg aaatgcaggt
     4201 ggcgcacgtc ggtcatctct cctgtccgct ggctgctgcg ccggctctcc tgattcagtt
     4261 tcgcgttcac cgcctcgtca gcagccgcaa aatgaccgtc aagcagcagg aacgccagca
     4321 gccgcgccaa cacaatcccg acagccagcc cgcccgcgca ccaggcaatc ccgaacaggt
     4381 tagccggctg cagcaggtaa taatctgcgt ttgcgtagag gtccggacgc aggacggttt
     4441 ctccccagct ctcgataaac acggcgacaa ccagcccccc cagaaggggg ggtaagcggg
     4501 aaccccagaa aattccgcca ttccgcattg tggaattttt tgggggggtg gtccgcggca
     4561 tgacgacccg ccaaaggcta ccgcatctat ctgaggcgct gtggcgcgac gctgaaaccc
     4621 cggggaattc cgctactcca gttccaggtc cgcaatagtt cgtccaggtc gggtggcgta
     4681 cgccggaaac gccgattttt ccgcaaccgt ttctgcgttg tcggcaaggt ggtctcagag
     4741 agcgctcaag aagcggtttt tctcgtatgt ttagctacgg tggcctagga gcctgcgcgg
     4801 cagaagccaa atcggcggaa gatcgaggac gatacgggga tggctgccag ttaccttcct
     4861 taccgacccg accaatccta tctgctgccc ccttctctgg gagagtggct acctgaaggg
     4921 catcttgcct acttcatcag cgagactgtc gatacgctgg acttgagcgc attccacgcc
     4981 cggtatgccg gcggtggtcc gggcaatcag ccgtttcatc cggcgatgat ggtcaaagtg
     5041 ctgatctatg gttacgcgag cggcgtcttc tcttcgcgca aactagccag gaagctgtac
     5101 gaggatgtcg cgttgcgtgt gctggccgct ggaaacttcc cggcccaccg cacgctgagt
     5161 gacttccgtg ccctacacct gaccgagctt gagaatttgt tcgttcaggt ggtgcaactg
     5221 gcgcgcgaat gtgggctggt gaagcttggc acgatcgcgg tcgacggcac caaggtaaaa
     5281 gccaacgcca gccgccacaa ggcgatgagc tataagcgca tgaagccggc cgaggacgaa
     5341 ttgcattgcg agatcaaggc gctgcttgat cgcgccaagg ctaccgacga ccaggagcgt
     5401 aacgagccgg agctggacat tcctgccgag atttctcgcc gcgagaagcg cctggaggcg
     5461 atccaggcgg caaaggcgcg cctggaagcg cgccagcgtg aagcggacca ggcccggggg
     5521 cgcagcgaag acgatggccg ccggcctcgc catccggatg gctcggacaa gggcggtggc
     5581 tcgtacaaac gcgagtttgg tgtgccggat gaccgtgatc aggaaagctt caccgatccg
     5641 gacagccgga tcatgaaaca cgccggtggt ggctccgagc agagctacaa cgggtacaca
     5701 gcggtcgatg ccgagcacca gatcatcgtg gcggcggagt tgaccaactg cgccgcggac
     5761 agtcaggcgc tgctgggcat gctggcagca gttcaggcca acaccggaga aatgccggcc
     5821 cagacgctgg cggatgcggg attccgtagt gaggctgttc tggcaaaggt cgccgatcac
     5881 cacggcgatg tcatcgttgc cctcggccgc gagggacgtg aagatgccaa ggtcaatgcc
     5941 aagacccatc cgcatacggc ggcgattgcg gcgaaattga aaacggagca aggcgatgca
     6001 gcttaccgcc ggcgcaagtc gatcgtggag gctccgaatg gttggatcaa ggcggtgatg
     6061 ggattgcgtc agttcagcat gaggggcctg gacaaggtgc aagccgagtg gaagctcgtc
     6121 tgcatggcgc taaatctgag gcgaatggcg tatctgtgag ggcgaaggtt aaatggggcg
     6181 gctcaaatgc accccagtcg tcataacacg ccgcgcgccg caagattggt atccttggcg
     6241 ccgacgcctt gccaattgca gagagcgccg ccgccatcgt cagtgctcta cagaaaaccg
     6301 gtcacacggc tctgccgcgc agactcctag cctaaatgtg acagtggttg gtaatccatg
     6361 ccgcccgcaa gggcggcggt ggtgggccaa tagatgattt tcagagcctt actgcccgtt
     6421 gacgcccaat ccctcgagcg cgagtctagc cgcagcggcg atgacggcct cgctgtactt
     6481 gtcatccttg ttaggcgccc gggtgtagac ggccaacaca ataggtgcgc gcccagtggg
     6541 ccagacgacg gcatagtcat ttgccgtgcc atacactccg caggttccgg ttttgtctcc
     6601 gactgcccag tctgccggca ccgccgcgcg gatgcggtgg ttgccggtcg tgtttccctt
     6661 tagccaatca acaaactgct gccgctgcgg cgcagccagt gcagagccca gtgtcagttt
     6721 ttgtaagctt tccgtcacgg cgcgcggcga tgaggtatcg cgcgcatcgc ctgggatggc
     6781 ggagttcagc tccagctccc agcggtccag acggaacgtg gtatcgccga tagagcgcat
     6841 gaaggccgtc agcccggccg ggccgcccaa ctccttcagc aacaaattgg cggcggcgtt
     6901 atcactgtat tgcacggcgg ccgcggacag ctccgccacc gtcatgcctg ttgtcagata
     6961 tttttccgag atgggtgacc acggaaccag cgcatttttg ccgtaacgga tgggtgtgtc
     7021 cagcaagccg gcctgctgct ggctgcgagc cagcacagcg gcagcaagaa agcccttgaa
     7081 tgagctgcac agtgggaagc gctcctcagc gcggtaactt acagttgcgc ctgagccggt
     7141 atccatcgcg tacacaccga tggagccgcc aaagtcctgt tcgagtttag cgaatggttc
     7201 cgcgacgagg ttggtcagcg cggtggcaga aaagccagcc agcggccatg agagacaaga
     7261 cagcagaact agacggcgat acagtgacat caacgatatt ccttgtttga aggtggagct
     7321 aggtgtagcg gccggatgta atcaggccgc tacagctggg attatcaccg agcggcaagc
     7381 cgctccctct ccagaggctg taacggctgt aactgccccg gatgggcaca catcgggttg
     7441 gtaagtccct ggcaccacaa cgtccagcgc tattgaaaaa cgaatcaggt cggcgttcat
     7501 gggtcggcca cctcgcctga cctcggcatc cacgttacgg acggcctcag gaagtcctgg
     7561 ccaagccccg actattgggg cgcgaagata gcaccgaggg tacgccggtg tcaacaccaa
     7621 ctgaaaactg acccacttta cccctgaatc accaaagtaa tactgaccca cctggatcat
     7681 tcgggtttgg aatttttcct gaccactccc gccttcctct tgtccttcaa gcggtagctt
     7741 tcgccgctca gggtcaggat atgggcatgg tgcagcagcc gatccagcat cgcggctgtc
     7801 agggtggtat cgccggcaaa cgcgtcggcc cactggctga acggcaggtt cgaggtcagg
     7861 atcatcgccc ctttctcata gcgcttcgcc accacctgaa agaacaggtt cgcttcctcg
     7921 cgtccgaaag gcaggtagcc gatctcatcg atcaccagca gccgtggacc gaggatggcg
     7981 cggttgaagt attccttcag ccgcccttgt cgctgcgccg tgctcagttg cagcatcagg
     8041 tcggctgccg tgatgaagcg tgtcttgacc ccggcttgcg cggccttgta acccaaggcg
     8101 atggcgaggt gggtcttgcc gatgccagag ggtccgatca gcaccacgtt ctcggcccgt
     8161 tcgacaaacg ccagactgcc cagctcctgc accagtgcct tgggcacgcc ggggttgaag
     8221 ctgaagtcat agtcctccag ggtcttgatg cccgggaagc aagccatccg cgtcagcagt
     8281 tcgcggctgc gctgctggcg acaccccgct tcatgccgca acaggtgttc caggaagtcg
     8341 gtgaagctga agtcctcgcg caccgcctgc tgcgccagga cggggtaatg cgttgccacc
     8401 cgttcgagtt tgagttgctg gcacagggcg tcgatccgct catgctggag gttcatcggc
     8461 aggcctcccc aattgcgtca tagacagaca gtgggtgctg gagagattcc agtggtaccg
     8521 ggcggagact gttatccagc aggggggcct cgtcgcgccg cacacgggat ggcaagggtt
     8581 gcaggtgttc ccgctcctgc cgccaacggt cgatggggcg ctcgttcagg gtggcgtgga
     8641 cccgcacatt cgcctcgtct gccaaccagt cacggacgcg tcggttggca gcagcacaat
     8701 cgagcagcag ccccgtgccc ttcatccggg tcagcaacgg gttgtagaag ctctcgcgga
     8761 agtagcgatt gaagcgctcg accttgcctt tggtctgggc ccgatacggg cgacacagcc
     8821 ggatccggaa ccccaggtca tcggccagtt gaagcaagcc ggggtgaaaa cggtgcttgc
     8881 cgtcaccgta ggcatcgcgt tccagcacca cggtcttcat gttgtcgaac aacacctcgc
     8941 ggggcacacc gcccagatag tcaaaagcca gcaacaggga gtcccgcacg gactcgaagg
     9001 attcgtccgg tacgaaggtg acaaacgtca tgcggctgta tcccagcgtg gcgacgaagg
     9061 ccgacatggg ggatctggcc cggcgcaaga ccacgaaatc agcctgcaac tgccgtccgg
     9121 gctcggtctc gaaacggacg gccggacctg cttcgcggcg ggcgggcttg agcgtggcga
     9181 ggaaggcgcg caataacgag agaccgccgc catacccttg agcgcggatt tcccgattca
     9241 ggacggtggc aggcagccag atggggtggg cctgctcgac ccgttgccgc agataagatt
     9301 caaatggccc cagtttggtg gggcgtggtt cacggggctg gtatcgcgct accgacggat
     9361 cgcggaggta gcggcgcacg gtattgcgcg agacccccaa cgtgcgggcg atgtgccgga
     9421 tggagtggcc ctgtcgggca agaactctga tttccacggt ttgctcctgg gtcaacatcg
     9481 acggcctcga aaaggccgcc aaactagccc aggtggatca gttttacttc gctggggtgg
     9541 gtcagtttta cactgctgct aacacggaac cgctgaaaat tccgtcactc cagttccagg
     9601 cctgcgacga tcgcatcgag atcgatcgtc ttgccgctgc tttgaaaggt gtagtgcccg
     9661 ttgagcagga tgtgccgcca tgccgcaggc gaaatttttg tgatgagtgc cagcgccttg
     9721 ctgttgccgg ccgcctcgta cttggtcacc agccgcgaca agattgccga gttgtagaaa
     9781 atgatcgtgt tggcgatcag ccgtgcgcac tggttgctga tctcgatttc aatgtcggtg
     9841 cgaccggtca gttccttctt accgccgacc tgggcaatgg ccgagcgtag ctgatggtag
     9901 gactcgaggc gattttgcga gcggtgcacg ttgcgttcca gttgcggatc gcgcaggtag
     9961 cgaagcgtgt agatgctgcg gatgagcttg tcgaactcga agatcgcgcg ccgcgtcggg
    10021 ttcgtcgtgg tgtaggtgca cagcttgcgg atcagcgtgc cctgcgtcat ttccttcagc
    10081 ccgagtgtgg cgacgatccg gtcgatgttc ggcttctcgc gatggatgag atcgcagtcg
    10141 attttcccga ctggccgaat caggcacgcc tgatactgtg ctggatcgtc agcgcagtag
    10201 agttctttca attgcgcgtt gaggtcggtg aagcgcggct cgaaccgccg gccaaaccaa
    10261 tgcaggatgg cgaagttggc cttgttgacg ctgtgcatgt cgccggtgat cgcggtcggc
    10321 atgatgtccg acgtgttgcg ataccagatg tcgaacacgt ggtgggcctc gtagtcgtgc
    10381 gcgccgatca ggtagccgtt gagcgggatg tggttgcaca gcagcgtgta ggcgaccacg
    10441 cccttgccgc gcccgaagta cttgcgcgaa tagcgcgcct tcacggtcgg ccgttcgacg
    10501 ctgaatttct gcccgtcgac ggcaccgtac agcgtttcga ggtcgaacga gtagtatggg
    10561 aagatcggta gcgtggcgat ggcgttgctg atgcagtcgt tggccgcgtg cagcgttgcc
    10621 tggcgcaggt actgctggta gccgctatcc agcacgtggt acgggatgtc gctggtgcgc
    10681 gccatgacgt ggttgccgtg gttcatcgct tgcgcgatga tgaccgccat caggctgtca
    10741 gcgtcggcga ccttcttcgc gtagcgcggc tgcatgggcg tgaacgccga cagaaacttg
    10801 cactcgtcgt tgacgaagcg aaacacgtcg gccacgtcgc agaacggaag cttctcgtag
    10861 aatgcctttt cgcgcgcttt ctcattctcg ctcttgggct tgcgccaggt cagtttctgc
    10921 gtgtccttgt tgtattcgag gtgcgtcagc ttgccctgtt tcagctcgcg gttgaacgcc
    10981 agccactgcg tgcgcagttc ggcagtcagc gcatcgagtt gggcatggac gggttgctgc
    11041 aggaagggga tctccatttt tgcgagcaca tcgatcttcc tgtccatctc aaccagttca
    11101 tctgagaagt gccggtgttg caggctgtcg tcgaggtaga gttcacccga ttggagacgc
    11161 ttcctgatct ggcggtacag ccagaactcg tagcggtcag cgtgcaggcc ggttggttta
    11221 ccgtcggcgt cgaaggtcag caggtacggc cgcaagcgtt tcggaagtgt cgccgcgggc
    11281 cactcgtcga gtggccgttg cgacagccgc tgctgcttgg caaaaacacc tttggcccag
    11341 gccagcgcgg caagccatgg actgtctgga ttggagccgg agaggtcgag cgcaacgtac
    11401 agtggacgaa gatggcggcg catgcggtcg gccagcccgt ccaccgcctg ccactgcaag
    11461 gccagcttgc tcgccggctt cacgctcata cgctgcgccg tggtttgcag cgtatcgcga
    11521 ggcatgatct tgtaggcgcg ctgccgcacc tcgccgaagg gcgtgggatc ggccacgcta
    11581 tcatcaacgt agagtgacag caggcggcct acccgcggcg tttcctgctg acggcgcacc
    11641 tgctcgtcgg caaaggattg tttggcacca gcgctgcttt cgtcctccaa ctgcttcatg
    11701 tggtacgcca tcgcatcgac caggttgtcg gagagctgcc ggtagcgtac ccaggcatag
    11761 cacagcaggt agagttgggt ctgatcggcc ttcagattgc gcaggtcgtg gacggtgtag
    11821 aagtttgcca ggctcgcgta gtacagcagg ttctgctgcg agacgtcgag tttaggcagc
    11881 agtgtcttgg cgattgcgtg cagcggctcc agcgtggcgc gcttttcgcg ctcgcggacc
    11941 atctggcgcc agccgaaatt cttggcgtcc tgcttgagcg ccgccagttg cgacagggtg
    12001 tcatcacgga ccagaagctg gctcagcgcg gccttggcag attcgtccaa cgcttgctcc
    12061 agcagattgc ccaggcgccg gcgctcggcg gatagcgttt cgctgaccaa ctcttgcaag
    12121 gtcgtatagc cgggccggat aatcttgtgc tcattgagcc agacgatcag ctcggcggcg
    12181 acgaaccccg gcgttacgtc acgccgcacg gtccgtgcgg cctgctgctc gagctgcggc
    12241 aggaaggcgg ccgaccacgg ccagtagccg aatagtttgg cgatctgctc gcgctgggtg
    12301 tagcgttcat gcttggtgat cgccttgggt tcgaacacct cgccgtggaa atagcggctc
    12361 agcacgaaag cgcaatcgtc ctcgacttcg tcccagtcga aactgaagaa ggcatgcttg
    12421 gccttgaagt agccgatctg caagaggcaa tagaccttgg catgaagact gggccggctg
    12481 ttggcaagcg ccaactcggt ttctgtcaca gccagatatt ccagctgctg cgcatcatcg
    12541 aactccggca ggccatacaa ggcctcctgt tcggcgtcgg ataggacgct gagtagcttg
    12601 ttcttcttgc tcatggcccg ttcttgctat cttgaggttt cgtagaaaca tggggcattt
    12661 tcgattctac tgaaataatc gttattatcg cgttactcgc ttttcgaatc gcaacctgtc
    12721 catatgaaaa cgggccagac tacggcttcg agttctaccc cagtcggctt tcccgatgcg
    12781 gattcgctgg ctgccttgcg cggctggtac gcgggactca gctctcgcgc ggccgttgaa
    12841 cactacctgg cggcacgcaa ggccgccggt caatcagcgc gagggatgct ggggcatatc
    12901 cgccgccagc tcatcgtttt cgccaacagc cgccaccggc cggatctggc cgacgtgttc
    12961 cagcacgccc ccgaagagcg acaggggcgc gcgggtgccg tcgaacgcgc gatccggctc
    13021 ttgcccacgc tgccggcgcc gaagccccag atcagcgaca gcatcgacca gtggctgtct
    13081 ccgaggaccg tcagggcact gcaggcgtac ggtatccaca ccctctcggc gctgaccgtg
    13141 cgcattcccc gccggcgtgg ctggtggaaa gccatcgagg gactcggcat gacaggcgcc
    13201 cggcaggtcg aggctttctt tgccgcacat ccgcagctca ccgagcgcgc ccgggccctg
    13261 atcccgatta ttcagcccag cggcatcgtg ccgtgggagc agttgcgtct gccgaacgaa
    13321 gtcgacggct cgcagggcaa tttccgggcc ccgcgcaacg cttgcacgct gaatgcgacc
    13381 aacgactacg aggccgtgca ggcctggctg gcgctgcacg agactgtcgc cacacagcgc
    13441 gcctatcgca aggaggctgc gcggctaatc ctgtgggcca tcgtcgaacg cggacgggcg
    13501 ctatcatccc tgaccacgga cgatgcaatc gcgtaccggg cctttgtccg gcacccgacc
    13561 ccgcgcgagc gttgggtggg gccacctcga ccacgcgatt cggtggaatg gcgccccttc
    13621 tcgggcggct tgtccgcacg ctcggcagcg tatgcgctga cggtgctctc ggcgctgttc
    13681 cggtggctca tcgagcagcg ctatgtgctg gccaaccctt tcgccggcgt caaggtacgc
    13741 ggtcacgcct tgcggcccgc actggatacg gcgcgaggct ttaccgaggg agaatggcta
    13801 ctgctgcgcg ccattgcaga cggcctggaa tggtcctacg gctggtccga gccggcagca
    13861 caacgcctgc gcttcatgct cgacttcggc tatgccacgg gcctgcgcgc tagcgaactg
    13921 gtcggcgccg tcctgggtaa tgtccgcctc gacgagcacg gtgaccactg gctgcatttg
    13981 gttggcaaag gtggcaaacc aggtaaggtg gccttgccgc cgctcgcgta tacggcgctg
    14041 gaccaatact tggcacagcg tcaactgcca gtcagccggg aacggtggaa tccgaaaacg
    14101 cccctggtgg gcagtcttgg ggaagacggt aatgccggca tcaccggccc tcacctttgg
    14161 tgcgtgttgc gaagattctt tacgcaagcc gctgaggcca ttgaggccga tcatccggtc
    14221 gccgccgaaa agctgcgccg tgccacgcct cattggatgc gtcacagtca tgccagccat
    14281 gcgttggccc ggggagctca gctcaccgcg gtgcgcgaca acctacgcca tgcgtcgatc
    14341 gccacgacgt cgatgtattt gcatggcgat gagctcgagc gcgccaggca gatgcggcag
    14401 gcttttggcg ctcgtcacgt caagcgagga gtcgactgaa ttttcatcat acggaatgac
    14461 ggaattttct gggattcccg cttagaaccc ccagaagggc cagaccggcc gcgccggtca
    14521 gccagtacgc gtagttccag acatgtcgac gtgccctgac catccgcccg ggcgaatcca
    14581 gcgaggccag caccgaaaat ggcgctggcc gtttattatc gcgcttatag cgatcggcat
    14641 actcccgtcg ctccttatga ctcagcccca caaaacgcat ccgtccggcc caaagttcag
    14701 ccagaccgaa aaacaggccg ataactagga aagccccggc cagaccgtaa tactcctggt
    14761 acagccagct gacccacgga taaatctgcc gggccagctc cggaatgtgc cacttccagg
    14821 caagcgaatc cgtattaaac atgttctctc tccttcagac gatggtttgc cggcgtgatg
    14881 tgcagccccc gctgcacaag ccgcggacat gccccaaggc atggcggcgg cggtcacgtc
    14941 cgtggtgatt gcgttcagct ttcaccacgg aggccagcct ctttccgccc catgcggaaa
    15001 aggcgcagcc ccggaggaac aacgagcacg ccccagcgtg tgagaggaaa aggcggcacc
    15061 ccagtgcggt cttttccggt gttccggccc ccgtcagagt tcgccatagc gagcggctga
    15121 ccacccgcaa aatcaggagc agctttgctg cttcgccagg tgcgtccagc accgtggatt
    15181 tttgtgggtg gtcaggcgtg agcctgacgg gggccgggtg aatttctggc gtggccggcg
    15241 tccagccgga cggagccaga aagaggggga gagaccgtgc gtcggtggcg tccagccagc
    15301 gtaagcaggg gatatccccc tgaggtcagc cacgccctcg cggggatgac ctgtatttct
    15361 ccgtaaggag aaaaaagcaa cagagatagg ttaacgtaaa atgttcagcg aaaaaccgat
    15421 atgattcacc tatcctggta atttattatc agggaatata aagacttaat caggggacaa
    15481 tatgccacat cagcgcgtcc ggtgtccgtc ttgtaggtgc cggggaaatt gcgcctcctc
    15541 gctcactcgg tcgctacgct ccggccgtga gactgcggcg ggcgctgcgg acacatgcaa
    15601 agttacccac agattccgtg aataagcagg ggactaacat gtgaggcaaa acggcaaggc
    15661 cacgcaggtg gcgtttttcc ataggctccg ccctcctgac tgagttcaca taaacagacg
    15721 ctttttcggt gcatctgtgg gagccggtgg ctcaaccatg aatcagtcag gagtggcgaa
    15781 acccgacagg acttaaagat catcaccgtt tccgatgaat cgctccctct tgcgctctcc
    15841 tgttccaacc ctgccgtttc ccggatacct gttccgcctt tctcccttgc gggaagtgtg
    15901 gcgctttctc atagctcaca ctctggtatc tcggctcggt gtaggtcgtt cgctccaagc
    15961 tgggctgtaa gcaagaaccc cccgttcagc ccgactgctg cgccttatcc ggtaactgtt
    16021 cacttgagtc caacccggaa aagcacgcaa aacgccactg gcagcagcca ttggtaactg
    16081 ggagttcgca gaggatttgt ttagctaaac acgcggttgc tcttgaagtg tgcgccaaag
    16141 tccggctaca ctggaaggac agatttggtt gctgtgctct gcgaaagcca gttaccacgg
    16201 ttaagcagtt ccccaactga cttaaccttc gatcaaacca cctccccagg tggttttttc
    16261 gtttacaggg caaaagatta cgcgcagaaa aaaaggatct caagaagatc ctttgatctt
    16321 ttctactgaa ccgcgatccc cgtcagttca gaggaggacg atggtgccac cgttccaccc
    16381 tgaacatccc ggatatagtt tgcctgacat gcgaccagaa gaaagcctga aaaaatcaat
    16441 ataaaaagaa aaacaacctt tacctttttc atataccttc cctgtattta aaaaccccgg
    16501 tattcatccc tgaacaccgg aagtctgtat ttcaaatcat ccttgataac ttttgcttac
    16561 cagttaccat cccggtaaac aaaggataca aagtaatcaa atttactaat atcgattaca
    16621 tttttaaagt gtggctgtaa tatcgaaacc catgattttt caacatcaaa ccaaccatta
    16681 ttaatattat cctttaaagg catccccaga ctttcaatga cagaaccatc atcaccgaag
    16741 tcttttgagt attcaccacc tttaaactct tcggttttct tatcaaacca atgaatatgt
    16801 aatttaagcc ccatatttac ctcttaaaga tattttttaa tgtttcgttt tggatccggc
    16861 cctttaacct gcttacccgt ttttggatcg aatgccccga ggtgttcgcc atcactggcg
    16921 cggtaccctt caagctcacc gtgctgggaa tcccattcat aaattttacg ctttttatca
    16981 ccataccatc gggcccgctt accaccacca ccttgtttag gggttttagg tttaccctct
    17041 ttcaactctc ccaacccctt aatatcttca gtcttgggat caggaaaata atcatggccg
    17101 taatctttag ttcccttacg aggttttttc ttttcctcat ttaatttatt ttctgcatcc
    17161 ttcgcttttt tctccttttg tttccggctc tccatcgccc cggaaagcgc agccttatcc
    17221 ctggataagg attcattcat ttcgtttaaa gatgtctggg cagcttttaa tttctcattc
    17281 tgattctgaa tatccttatc aagatagcga acctgatcct gccacccgga gccatattca
    17341 tgaggcgggt tataagtcac aaaatcatct ttatttgcct ctgcctcttt taccttttta
    17401 tcggcttcct gaacagcagc ccttgcaccg gggatcgcct tctctgtcga tgcaatgcga
    17461 ctgtttaagg tcgcaatatt tttatcttca gcatccagct cagctttcgc tttatcatac
    17521 tctcttttca gcccctcttc cgggtgagca gcgtcccatg cctgctggcg acgcttttct
    17581 tcctccagac gctgttttac ctgtgccgga gtaagaacat ccgtcaccga cacatagacc
    17641 ggtttctgtc cgctctcttt cgggaaacga ataacggctt cacgggagtt accaccggcc
    17701 gtaaaaccag ccggacgtga atcacctttt tcagcaataa tgccttttgg cggggctttc
    17761 gcggccggaa cacctttagg tacgctcacc tgcagagacg ggagacccgg aatcgacaca
    17821 ctgaataccc ccggacgttt tgtcggtttc gcatccacca caggaacact cattggccgg
    17881 ccggtgacaa ccgcaatatg ctgccgctcg tccttcacaa tatccgccac acgtttagtg
    17941 acgctgaccg tcgcctggtc cagcggcagg gagctgaccg gcgtctccgt taccgtgtct
    18001 gccggcaatg acgtcacgat ttttgacatc attttcggat catcttttgc tatctcagaa
    18061 ggcagcactc cgtaaatcgc aatcccccac agaccaaact taaacggacc tttcagggca
    18121 gccagcacat cagcaacagc ggccgacaac gcatcgccgg aaacggataa agccagtcct
    18181 tcagcccccg gagtggccaa ggcaggcaga ccgaaggcca tcgcggtggc cgaagactgt
    18241 ccgccaccag agctcccgct atgattgccg ctgttaccgc cattaccacc gggtttactc
    18301 ccgccgttac caaactcccc cgggttatag ttatgaatat ccccgttagg tgtatgcgtc
    18361 gtaccccagc ccggcccgct gtttggatcc gtaccaccac ctgatgaagg gccaccttta
    18421 cctgatgtac cgttcacatt cccactggcc tgaccaccat tgtgtcccag acctgaatta
    18481 cccggacctc gtccgtctcc gccactcata tacttttcct ctttgacttt taaaacaata
    18541 aactaaaata aaatactgta catataacca ctggttttat atacagtata aaaattacgc
    18601 tgccttgttt ttcatgtcaa gtctgtaaat ttgcgttttt gtgaaaatga tcaaaaaaac
    18661 agccactcac accatgcgca atcccctcca gatgcaacaa aaaccagcac aaacggcgcc
    18721 gttctccggc ctcagtatgt tttactgaaa tcattatatg agataccaga aagccccctc
    18781 cgggacagga aaagaaacgg ggggtctggt tcgggttgtt cggtcactga acacggtcag
    18841 aaactgatga taagatagcc tgcggatata taactcaatg agaaaaaaga attaaaggta
    18901 aggagacgct catgagacgt tccggcagca aactgtgtct tatcgccatg ataacagcga
    18961 cagcaactct cactgcctgt gctccaaagg gcagcgtgga acagcatacc cggcattacg
    19021 tatatgcttc agatgacggt tttgatccca atttttccac ccagaaagct gacacaacac
    19081 gaatgatggt gccttttttc cggcagttct gggatatggg cgcaaaggat aaagcgaccg
    19141 gaaaatcacg gagtgatgtg cagcaacgca ttcagcagtt tcacagtcag gaatttttaa
    19201 actcactcca aggcacaaca caatttgcgg gtaccgatta ccgcagcaaa gacctcacac
    19261 cgaaaaaatc aaggctactg gctgacacca tttcagctgt ttatc
//
