LOCUS       NZ_CP036303            10060 bp    DNA     circular CON 26-NOV-2023
DEFINITION  Klebsiella pneumoniae subsp. pneumoniae strain WCHKP015093 plasmid
            p2_015093, complete sequence.
ACCESSION   NZ_CP036303
VERSION     NZ_CP036303.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07609144
            Assembly: GCF_002852365.2
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 10060)
  AUTHORS   Lin,J., Long,H., Feng,Y. and Zong,Z.
  TITLE     The complete genome of Klebsiella pneumoniae strain WCHKP015093
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10060)
  AUTHORS   Lin,J., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2019) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
REFERENCE   3  (bases 1 to 10060)
  AUTHORS   Liu,L., Lu,Y., Lin,J., Yang,B., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/26/2023 03:16:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,854
            CDSs (total)                      :: 5,734
            Genes (coding)                    :: 5,584
            CDSs (with protein)               :: 5,584
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 57 of 150
            Pseudo Genes (incomplete)         :: 98 of 150
            Pseudo Genes (internal stop)      :: 17 of 150
            Pseudo Genes (multiple problems)  :: 22 of 150
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036303.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..10060
                     /organism="Klebsiella pneumoniae subsp. pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="WCHKP015093"
                     /host="Homo sapiens"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:72407"
                     /plasmid="p2_015093"
                     /geo_loc_name="China: Sichuan, Chengdu"
                     /collection_date="2017-04-05"
     gene            complement(join(9627..10060,1..1252))
                     /locus_tag="CLQ99_RS29920"
                     /old_locus_tag="CLQ99_29920"
     CDS             complement(join(9627..10060,1..1252))
                     /locus_tag="CLQ99_RS29920"
                     /old_locus_tag="CLQ99_29920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            1579..1824
                     /locus_tag="CLQ99_RS29925"
                     /old_locus_tag="CLQ99_29925"
     CDS             1579..1824
                     /locus_tag="CLQ99_RS29925"
                     /old_locus_tag="CLQ99_29925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            2098..2469
                     /gene="tolA"
                     /locus_tag="CLQ99_RS29930"
                     /old_locus_tag="CLQ99_29930"
     CDS             2098..2469
                     /gene="tolA"
                     /locus_tag="CLQ99_RS29930"
                     /old_locus_tag="CLQ99_29930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            2466..2831
                     /locus_tag="CLQ99_RS31860"
     CDS             2466..2831
                     /locus_tag="CLQ99_RS31860"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_072354022.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            3006..3284
                     /locus_tag="CLQ99_RS29940"
                     /old_locus_tag="CLQ99_29940"
     CDS             3006..3284
                     /locus_tag="CLQ99_RS29940"
                     /old_locus_tag="CLQ99_29940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            3272..3586
                     /locus_tag="CLQ99_RS29945"
                     /old_locus_tag="CLQ99_29945"
     CDS             3272..3586
                     /locus_tag="CLQ99_RS29945"
                     /old_locus_tag="CLQ99_29945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            3750..4178
                     /locus_tag="CLQ99_RS29950"
                     /old_locus_tag="CLQ99_29950"
     CDS             3750..4178
                     /locus_tag="CLQ99_RS29950"
                     /old_locus_tag="CLQ99_29950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            4204..4383
                     /locus_tag="CLQ99_RS29955"
                     /old_locus_tag="CLQ99_29955"
     CDS             4204..4383
                     /locus_tag="CLQ99_RS29955"
                     /old_locus_tag="CLQ99_29955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(4410..4940)
                     /locus_tag="CLQ99_RS29960"
                     /old_locus_tag="CLQ99_29960"
     CDS             complement(4410..4940)
                     /locus_tag="CLQ99_RS29960"
                     /old_locus_tag="CLQ99_29960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(4947..5678)
                     /gene="mobC"
                     /locus_tag="CLQ99_RS29965"
                     /old_locus_tag="CLQ99_29965"
     CDS             complement(4947..5678)
                     /gene="mobC"
                     /locus_tag="CLQ99_RS29965"
                     /old_locus_tag="CLQ99_29965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            complement(5678..7642)
                     /locus_tag="CLQ99_RS29970"
                     /old_locus_tag="CLQ99_29970"
     CDS             complement(5678..7642)
                     /locus_tag="CLQ99_RS29970"
                     /old_locus_tag="CLQ99_29970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_071177727.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(9126..9275)
                     /locus_tag="CLQ99_RS29980"
                     /old_locus_tag="CLQ99_29980"
     CDS             complement(9126..9275)
                     /locus_tag="CLQ99_RS29980"
                     /old_locus_tag="CLQ99_29980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(9360..9617)
                     /locus_tag="CLQ99_RS29985"
                     /old_locus_tag="CLQ99_29985"
     CDS             complement(9360..9617)
                     /locus_tag="CLQ99_RS29985"
                     /old_locus_tag="CLQ99_29985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     BGC             1..6252
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          8445..9023
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(4951..5678)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.34e-140"
ORIGIN
        1 gagccgcttt taatttctca ttctgattct gaatatcctt atcaagatag cgaacctgat
       61 cctgccaccc ggagccatat tcatgaggcg ggttataagt cacaaaatca tctttatttg
      121 cctctgcctc ttttaccttt ttatcggctt cctgaacagc agcccttgca ccggggagcg
      181 ccttctctgt cgatgcaatg cggctgttta aggtcgcaat atttttatct tcggcatcca
      241 gctcagcttt cgctttatca tagtctcttt tcagcccctc ttccggatga gcggcgtccc
      301 atgcctgctg gcgacgcttt tcttcctcct gacgctgttt tacctgtgcc ggggtaagaa
      361 catctgtcac cgacacataa accggcttct gtccggtctc tttcgggaaa cgaataacgg
      421 cctcacggga gttaccaccg gctgtaaaac cagccggacg tgaatcacct ttttcagcaa
      481 caatgccttt tggcggggct ttcgctgtcg gaacaccttt cggtacgctc acctgcagag
      541 acgggagacc cggaatcgac acactgaata cccccggacg ttttgtcggt ttcgcatcca
      601 ccacagggac actcattggc cgacctgcga caaccgcaat atgctgccgc tcatccttca
      661 ccacatccac aacccgttgt ctgacacgaa ccgtcgcctg gtccagtggt aaagtacttg
      721 ccggagtctc cgtcaccgca tcggccggta atgacgtcat aatttttgac atcattttcg
      781 gatcatcttt tgcaatctca gaaggcagca caccgtagat cgcaatcccc cacagaccaa
      841 acttaaacgg ccccttcagg gcagccagca catcagcaac ggcggccgac aacgcatcgc
      901 cggaaactga taaagccagt ccttcagccc ccggagtagc cagggcaggc agaccgaagg
      961 ccatcgcagt ggccgaagac tgtccgccac cagagctacc gctatgattg ccgctgttac
     1021 caccattacc accgggttta ctcccgccgt taccaaactc ccccggatta tagttatgaa
     1081 tatctccatt cggcgtatgc gtcgtacccc agcccggccc gctgtttgga tccgtaccac
     1141 cacctgatga agggccacct ttaccagacg taccgttcac attcccactg gcctgaccac
     1201 cattatgtcc cagacctgaa ttacccggac ctcgaccgtc tccaccactc ataccgtttt
     1261 cctctttgac atttaaaaca ataaattaaa gccaacatac tgtacatata cacagtataa
     1321 ttattacctt actcctcccg ttttcaggtg tcaatatatg agattagttc tcatcttcag
     1381 gcacaaaaaa gcgcccggag ccacctgtaa gcagatcgcg tcttttcccg aaaatttctc
     1441 atggcaacaa attttattat ttaagacatt catcacactt acatttcaga tggtatagac
     1501 acatctgaaa gctaactggc atgaggagag gacctgcggt taaactgttc gggaaacctg
     1561 agacgcccgg aggccactat gacgcacctg aaactgactc ccgctgaaga aaagcgcctg
     1621 gcggacgcct ttgtcgctca ggcactggcc atgggcctga aagggaacaa aacgctgcca
     1681 aaggcggtaa aacaacaggt gcgggaaagg gtgcttcgtg ccattcagga cgaacgtgaa
     1741 gccaggcggg cgcaggaaat gcgtcgggag aaatacgagg ctacggaaac caccttcacc
     1801 tggcagccac agcgccgccg gtaaggggta tttaccataa cgtcgcattg cccgcaccgc
     1861 tcagacggtc tgagggcgtt tccggcggct acgggataaa acaggcaaca aaccacccgg
     1921 aaaaccgccg gaaacgcgcc cggtaaattg taacccgctg catgcctatg cacgcaactg
     1981 catggcgggc cgtttggtgt aaaaacgata cgataagccg tgtttatgta aatgaacgtg
     2041 gccgtaaaga gtgacaaata tacatgtaac attttttact gacaggtcat caacccgatg
     2101 cgtttaatac cctttatcct gctggcattg tgcagcccct tactcctgac ggcctgtaag
     2161 cattccacca cccagccgcc gaaaatttat actctggata agtcatctaa aatcagtagc
     2221 tacgctgcgg ccatcaagac cgctgttgaa atgcagatgt ttgaaccaga ggcctatgcg
     2281 ggaaaaatgt gcaccgtgcg gatatccata caacgtgatg gcactctgaa cagcgccatt
     2341 gctgaaggag gagatccgaa actctgtaaa gcagcaatat cagccgttac ccacgccaaa
     2401 attccgccgg caccggatga aaatacctgg caaatattca aaaacgcccc tctggatttc
     2461 agaccatgaa agcttttact ctgacagtgc tggcggccat gttcctcact ccggtacatg
     2521 cgataccact aaaacccgta accacactgc agccaaccta cccggtacag gccgcagcaa
     2581 aacgcatcga aggtcaggtg accgccacgt ttgatattct ggacgatgga cgagtggaca
     2641 acgtgtcgct taccggctgt cacctttttt ttcgggaaac gctgacggca atgaggcact
     2701 ggctatatcc cgcagggcac ccggcaatgc gacaggttat aaattttgaa ttcagtctga
     2761 aaaatgacgg cttacaggat ccgcgaccag tcaccaccca aaagctcaat gatgatggtt
     2821 gccgccagta acaggtcctt taacccgcag gctgcaatag tcctggatga tgagtgagcc
     2881 tgtagcagcc ctgattagtg gaagcgaagc tgaaaaatgg gcagcaaaag ccgtatttct
     2941 ggcaaatagc gccgccacgg attaaagtag tcatgtgtaa tacatatgac tacaaagggg
     3001 cttttatgtc atcagcaaca tccatcaggc tcgatgaaga acttaaggac cggctgaaaa
     3061 cgctggccga tgaccggcac cgctcagcgc acgcgctaat gctggaggca atcaccgaat
     3121 acatcgaccg ggaagagaag cgcagccagt acctgcggga cggacaggcc gcatggcagc
     3181 actatcagga aacgggtctg caccttactg cggaagaagc ggaagcctgg ataagtacct
     3241 ggggaactga gaacgagcag gatgctccgc catgccacag gtaacgattt ccgcgctggc
     3301 acagcgcgat ttacaacgcc ttcaggactt tctcaaaacc aaaaatcggc tggcagccag
     3361 aaaaggaggt gaggtgatcg tccgggctat ccagcaactg aaaacattgc cagacattgg
     3421 ccgcccggtg ccgtttctgc cgctggaata taaggaactg gtgatcgggt ttggcgacag
     3481 tggctatgtg atgctctacc gccacgaccg ggaaatggac cagattgtga tcgtcaccgt
     3541 caggcatcag aaagaatccg ggtatccggg ggcagacagc ctctaataac cgatgacggg
     3601 ggcgcaattc attgcgtggc cgtcgccggt ttgacaagcg cagcgcgtca gaaaaccaca
     3661 tcctgaacgg aaaaacgggt aaaattcagc gatacattta ccgtgagaaa ttacacacct
     3721 ttcacacccg ataaaatcag gggtatacag tggcgaaaac attgctcaac ctttcacagg
     3781 cagcacaagc cgcgggcatt accagaagaa cgctatacaa tcatgtaaaa cagggaaagg
     3841 ttaccgtgtc acgtgacggg aaaaacaacc ctgtcgtgga tgtgtcagaa ctgatccgtg
     3901 tatacggaaa tgtgaatatc cctgagaaac aaattcccgg catttcacac cgtgaaaata
     3961 cacaaaaaaa tttcccacag gaacagcttc tggcaatgca aaaggaactg gccgatctcc
     4021 ggcaggctgt caccctgatg ctggaagata aaacatcccg ggaagaagaa cgccgccagc
     4081 acgatgatga gcgccggaaa ctccaggccg aagtggacag attgacaaca gaactgacac
     4141 agaagaaaaa acgcttctgg tccggctggt ttagctgaga acttaccgaa gggaatggag
     4201 aacatgacga agcaggaaaa aactgccctc aatatggcta aattcattaa ggatcagtcg
     4261 ctgctgttgc tggaaaagct gaacgagctg gacatggata ccccggccga catgtgcgaa
     4321 cggcttcacg aggatgcgga aacactctgg caggtgatgc gggataagct cggggaagaa
     4381 taacagcacc ggccatgccg gtgctggcgt tattttttgc cgaacggcca ccaccggcgg
     4441 gcgggtttgt cctccggcag ttcaggcacc ggcacgttaa aatagcggct gttatattcc
     4501 cgcatcagct ccgctttcag cttctcgttc accgcgcttt ccccgtgccg ctcgctgacc
     4561 acctcaatca tcgcgttaat ctgctccggt gagcacttcc cggcatcaac cacctgcaca
     4621 ccgttctcga tggcgaaccg ctccaccttt cgatagaggt aatcacacag cttcattcct
     4681 gtgggtttgt cccgttccca ttgcggattt tcaccggtga aaaagtacgt ggctttttcg
     4741 tcgctgttga gccgctcgtc atacatcccg atggatttca tcatcgccag atgctgggcc
     4801 cggtcgacaa aacagaaaac atacgccccg gtctgccagg cgagcaccac catgtcttcc
     4861 agatgctcgc tggttggcat aatgcagcgc tcgccgtctt tgtcttccac gtcctcaata
     4921 aataccatgt acagcgccat aatccctcac tccgttgtca taaatttaaa gcacgcgaac
     4981 agcctctccc ggtccagctc caccgttttg cgggcctcgc cggtctgtgg attcacgatt
     5041 tcatccaccg ccagaatcgc ccgctgtacc cggacaagcg tcggccggtc agggcagatg
     5101 taccagattt catcgatgcc gttcgcccgg cggttgaaca gatacccgga caccacttcc
     5161 tgataccgcc tgcggctctt gacggtgcgc tctacctcaa atgccaccgt tctgccgtcc
     5221 agctccgcca gcgcgtccgg cactttcatc cctttcaggg ccatacggtg caggtaccgc
     5281 cagccggtgg ccccccggcc ctccatggag aggcgcaggg actgcacggc cagccggtgc
     5341 ggcagctgcg ccgccgacac ccttgacggc tgaaacggaa taacgtccgt cagcggctcg
     5401 tcctcgtcga acgagaacgc caccccgtgc ggcgtcagcc cccacacgct gacctgacgg
     5461 ccgtcaaccg ggtatttcgc ccggaccagc agccctttcg ccaccagact gtccaggaag
     5521 cggtaaaccg gctgtaccgc cgcaatcccc agccgtcgcg caaccagctc cgccgtggaa
     5581 cacagctctt cccgcagcca gcgcagggtc agccgtgttt tctccgcgtt ccgcgcctgc
     5641 cgcttcgcgt ggctgacgtt gtactgctcc agtgtcatca gtaaagcccc gcaaaatcat
     5701 catccgcttt tggtccgccg ccgtcggccg gaggcaggta ctccgccagc gggtccgttt
     5761 tcgccagcac cgggaaggtt ttcagcgaaa tttcccggcg ctcaacccgc agcgggctgc
     5821 tgaacgccag ccgcgccacg cccagcccgg tcatcaccgc gaacccgtca ggcaggtgtt
     5881 gcagggtgtt cacgtcaaac agcggccgcg cctccttctg gatgaagctg tcgccgctga
     5941 tgtgctccac gttccccgcc tcccggctgg cccggcggcg ctccacgtcc acccggatct
     6001 ccccggtctg gcccgccgcc cactgcgcgg actcctggct ggccgcgcga tagaaccagc
     6061 ggatcggcgt gttatccagt accgtggttt tcacaaaatc agcgggcaga tcctgcccgc
     6121 actgaccgaa gtcgcccagc gactggtgcg cgagcagcag gttgcagtcc cggctgcgca
     6181 gcgtccccag cgcgttcagc acgtacttcg acagcagata tttaatctca tcgagcatga
     6241 tgctcgcgtg cggccacctc cggaactcat cccgcgcaat gatgatttgc gcgcagcggg
     6301 caaacagcat cttctgcacc cggatcaccg cctcatcgtc catcgagccg atgacgtaca
     6361 ggcagccgcc gccgttgatt atccccgcca catcgatacc gctgtccgtc tgcaggacgc
     6421 tcaggtcggc cacgttctcc agcttggtga tcagcccctt cacgtccttt ttcagggcct
     6481 ccggcaacgc gtacgccgcc gccagcacct gctgaatgtt tgccccctgc gggaactgct
     6541 ccgcaatcag cttcgccgct ttctgctcgc tgatgcggta gtggtccgcc acgtcgccgg
     6601 tctcactcag gttaaacccg gcaaccagca gattcttcag ggcgtactgg tcgagatcgc
     6661 ggaacagatt cagctgcgcc ggtttccccg gccgcagatc cagcagggtg aagtccgggc
     6721 agtgcgcccg gaagacgtgc ggcgcccacg cgtccccttt ggggtcgaag tacaccacag
     6781 cgtccccgaa atcgcgtacg cagcgaatga gcgcgttggt ggccatcgcg ctcttgccgc
     6841 tcccgggcag gccgaggatc tgaatattgg tcttgcgcca ggtatcacga gggaccagca
     6901 ccggctggcc ctgctcatcc ttacccagaa acaccgcctg ctgtttccgg gcctgctccg
     6961 tggaaaaatc ggccagcgcg ttaaccggta ccggctcccc gaaatgcagg tggcggacgt
     7021 ctgtcatttc tccggtccgc tggctgctgc gccggctctc ctgattcagt ttcgcgttca
     7081 ccgcctcgtc agcggccgca aaatgaccat caagcagcag gaacgccagc agccgcgcca
     7141 gaaggacgcc ggcgacaagc cctccggcac accaggctat cccgaacagg ttagccggct
     7201 gcagcaggta ataatctgcg ttcgcataga ggtccgggcg caggacggtt tctccccagc
     7261 tctcgataaa cacggcgaca accagccccc ccagaagggc cagaccggca gcgccggtca
     7321 gccagtacgc gtagttccag acatgtcgcc gtgccctgac catccgcccg ggtgaatcca
     7381 gcgaggccag caccgaaaat ggcacagtcc ggttattatc gcgcttatag cgatcggcat
     7441 actcccgccg cgccttatgg ctcagcccca caaaacgcat tcggccggcc cagagttcag
     7501 ccagaccgaa aaacaggccg ataaccagaa aaaaaccggc cagactgtaa tactcccggt
     7561 acagccagct gacccacggg taaatctgcc gggccagctc cgggatatgc cactgccagg
     7621 caagcgaatc cgtattaaac atgcaatctc tctccttcag acgacgggtt taccggcgtg
     7681 atgcgcagcc cccgctgcac aagccgcgga catgccccaa ggcatggcgg cggcggtcac
     7741 gtccgtggtg attgcgttca gctttcaccg cggaggccag cctctttccg ccccatgcgg
     7801 aaaaggcgca gccccggagg aacaacgagc acgccccagc gtgtgagagg aaaaggcggc
     7861 accccagtgc ggtcttttcc ggtgttccgg cccccgtcag agttcgccat agcgagcggc
     7921 tgaccacccg caaaatcagg agcagctttg ctgcttcgtc aggtgcgtcc agcaccgtgg
     7981 atttttgtgg gtggtcaggc gtgagcctga cgggggccgg gtgaatttct ggcgtggccg
     8041 gcgtccagcc ggacagagcc agaaagaggg gaaaagaccg tgcgtcggtg gcgtccagcc
     8101 agcgtaagca aggtcttttc ccctgaagtc agccacgccc cagcggggat gacttgcatt
     8161 tctccgcaag gagaaaaaag caacagagat aggttaacgt aaaatgttca gcgaaaaacc
     8221 gacatggttc acctatcctg ataattgatc gtcagggaat agaaagactt aatcagggga
     8281 caatatccca catcagcgcg tccggtgacc gtcttgcagg tgccggggaa attgcgcctc
     8341 ctcgctcact cggtcgctac gctccgggcg tgagactgcg gcgggcgctg cggacacata
     8401 caaagttacc cacagattcc gtggataagc aggggactaa catgtgaggc aaaacggcag
     8461 ggccgcgccg gtggcgtttt tccataggct ccgccctcct gccagagttc acataaacag
     8521 acgctttttc ggtgcatctg tgggagccgt gaggctcaac catgaatctg acagtacggg
     8581 cgaaacccga caggacttaa agatccccac cgtttccggt aggtcgctcc ctcttgcgct
     8641 ctcctgttcc gaccctgccg tttaccggat acctgtccgc cgttctccct tgcgggaagt
     8701 gtggcgcttt ctcatagctc acacactggt atctcggctc ggtgtaggtc gttcgctcca
     8761 agctgggctg taagcaagaa ctccccgttc agcccgactg ctgcgcctta tccggtaact
     8821 gttcacttga gtccaacccg ggaaagcacg caaaacgcca ctggcagcag ccattggtaa
     8881 ctgggagttc gcagaggatt tgtttagcta aacacgcggt tgctcttgaa gtgtgcgcca
     8941 aagtccggct acactggaag gacagatttg gttgctgtgc tctgcgaaag ccagttacca
     9001 cggttaagca gttccccaac tgacttaacc ttcgatcaaa ccacctcccc aggtggtttt
     9061 ttcgtttaca gggcaaaaga ttacgcgcag aaaaaaagga tctcaagaag atcctttgat
     9121 cttttctact gaaccgcgat ccccgtcagt tcagaggagg acgatggtgc caccgttccg
     9181 ccctgaacat cccggatata atttgcctga catgcggcca gaagaaagcc agcaacaatc
     9241 aatataaaaa gaaaaatagt ctttaccttt ttcatatact ttccctgtat ttaaagactc
     9301 cggcattcat ccctgaacac cggaagtcag tatttcaaat catccttgat aattttttgt
     9361 taccagttac cgtcccgata atcaaaagct atataacaat tatccacatc aggttttatt
     9421 tgatttttaa aaaatggctg tagtaaagga acccattctt tcttcaaatc aaactcacca
     9481 ttattaatat tatcctttaa aggcattccc aagctttcaa tgacagaacc atcgtcacca
     9541 aagtctttag aatactcttc ccctttaaac tcttcagttt tcttatcaaa ccatgtcaaa
     9601 cgtaatttaa gccccatatt tacctctcaa agatattttt taatgttccg ttttggatct
     9661 ggccctttaa cctgcttacc cgttttggga tcaaatgcgc ctaggtgttc gccatcactg
     9721 gcacgatacc cttcaagctc accgtgctgg gaatcccatt cataaatttt acgtttttta
     9781 tcgccatacc atcgggcccg cttaccacca ccaccttgtt taggtgtttt aggatcacct
     9841 cgctttaact ctccaagtcc ctttatgtct tctgttttag gtactggatg ataatcatgg
     9901 ccgtagtctt tagtcccctt gcgaggcttg ttcttttcct catttaactt attttctgca
     9961 tccttcgctt ttttctcctt ttgtttccgg ctctccatcg ccccggtaag tgcagcctta
    10021 tctctggata aggattcatt cattgcgttt aaagatgcct
//
