LOCUS       NZ_CP036206            19897 bp    DNA     circular CON 18-JUN-2024
DEFINITION  Escherichia coli strain L725 plasmid punnamed3, complete sequence.
ACCESSION   NZ_CP036206
VERSION     NZ_CP036206.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN10219252
            Assembly: GCF_004301465.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19897)
  AUTHORS   Rao,Y.
  TITLE     Detection and characterization of Escherichia coli isolate carring
            NDM-enconding plasmid and MCR-carring plasimd
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19897)
  AUTHORS   Rao,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-FEB-2019) State Key Laboratory for Diagnosis and
            Treatment of Infectious Disease, Zhejiang University, No. 79
            Qingchun Road, Hangzhou 310003, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.11.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004301465.1-RS_2024_06_18
            Annotation Date                   :: 06/18/2024 05:40:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,000
            CDSs (total)                      :: 4,876
            Genes (coding)                    :: 4,716
            CDSs (with protein)               :: 4,716
            Genes (RNA)                       :: 124
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 93
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 53 of 160
            Pseudo Genes (incomplete)         :: 110 of 160
            Pseudo Genes (internal stop)      :: 25 of 160
            Pseudo Genes (multiple problems)  :: 27 of 160
            Pseudo Genes (short protein)      :: 1 of 160
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036206.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19897
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="L725"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="punnamed3"
                     /geo_loc_name="China: Hangzhou"
                     /lat_lon="30.3 N 120.2 E"
                     /collection_date="2017-07-21"
                     /collected_by="Tao Lv"
     gene            30..170
                     /locus_tag="D9K49_RS25340"
     CDS             30..170
                     /locus_tag="D9K49_RS25340"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001044210.1"
                     /translation="MNKTKGCLIANFATVPRDEQQHQEQKHVEKKQQQIEQRPRRAARI
                     G"
                     /name="hypothetical protein"
     gene            656..1393
                     /locus_tag="D9K49_RS25035"
                     /old_locus_tag="D9K49_25035"
     CDS             656..1393
                     /locus_tag="D9K49_RS25035"
                     /old_locus_tag="D9K49_25035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370723.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001446887.1"
                     /translation="MRRTKPVAAPMVARVYLRVSTDAQDLERQEAITTAAKAAGYYVAG
                     IYREKASGARADRPELLRMIGDLQPGEVVIAEKIDRISRLPLPEAERLVASIQAKGASL
                     AVPGVVDLSDLAAEAQGVAKIVLEAVQIMLFRLALQMARDDYEDRRERQRQGIELARQA
                     GRYKGRRADPKRRAQVVALRKSGYSINKTAELAGYSAAQVKRIWAEVSQAEAKQHGAFV
                     EDALTEADALAAVGQDERQEERA"
                     /name="recombinase family protein"
     gene            1390..1614
                     /locus_tag="D9K49_RS25040"
                     /old_locus_tag="D9K49_25040"
     CDS             1390..1614
                     /locus_tag="D9K49_RS25040"
                     /old_locus_tag="D9K49_25040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000743213.1"
                     /translation="MKKPNQDDEPFFITEEIAAEMIAGGYEFELPPIPCTIRLRDVLER
                     MTDAELALQPGEIADQERERCRRKPCSTS"
                     /name="hypothetical protein"
     gene            1825..3318
                     /locus_tag="D9K49_RS25045"
                     /old_locus_tag="D9K49_25045"
     CDS             1825..3318
                     /locus_tag="D9K49_RS25045"
                     /old_locus_tag="D9K49_25045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91-like element ISVsa3 family transposase"
                     /protein_id="WP_001120888.1"
                     /translation="MPHVAARTASRDRDTGRYQSHRPEQTLLYQIVDEYYPAFAALMAE
                     QGKELPGYVQREFEEFLQCGRLEHGFLRVRCESCHAEHLVAFSCKRRGFCPSCGARRMA
                     ESAALLVDEVLPEQPMRQWVLSFPFQLRFLFASRPEIMGWVLGIVYRVIATHLVKKAGH
                     THQVAKTGAVTLIQRFGSALNLNVHFHMLFLDGVYVEQSHGSARFRWVKAPTSPELTQL
                     THTIAHRVGRYLERQGLLERDVENSYLASDAVDDDPMTPLLGHSITYRIAVGSQAGRKV
                     FTLQTLPTSGDPFGDGIGKVAGSSLHAGVAARADERKKLERLCRYISRPAVSEKRLSLT
                     RGGNVRYQLKTPYRDGTTHVIFEPLDFIARLAALVPKPRVNLTRFHGVFAPNSRHRALV
                     TPAKRGRGNKVRVADEPATPAQRRASMTWAQRLKRVFNIDIETCSGCGGAMKVIACIED
                     PIVIKQILDHLKHKAETSGTRALPESRAPPAELLLGLFD"
                     /name="IS91-like element ISVsa3 family transposase"
     gene            3349..4233
                     /locus_tag="D9K49_RS25820"
                     /old_locus_tag="D9K49_25050"
     CDS             3349..4233
                     /locus_tag="D9K49_RS25820"
                     /old_locus_tag="D9K49_25050"
                     /inference="COORDINATES: protein motif:HMM:NF023271.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3363 domain-containing protein"
                     /protein_id="WP_001447541.1"
                     /translation="MLRSQRRGRDPPCWLSEKEPLVGKRRVNFQRCWLPVSRIGLHRRG
                     VERVNCGPKLLDLGEKGVYSSYTCRVPGGDYEGYVDAHVRRLEALRRAGIVERIDADQW
                     RIPDDLVSRAAAHDAGRDSQASVRVLSPVDLNKQIGSDGATWLDRRLIHGETADLAPTG
                     FGQQVREAMDQRREHHIEQGDATRSRDSRVFYRRNLLAILREREVAGVGSDMALSKGLP
                     FRAATDGESVSGKFTGTVHLSSGKFAVVEKSHEFTLVPWRPIIDRQLGREVMGIVQGGS
                     VSWQLGRQRGLER"
                     /name="DUF3363 domain-containing protein"
     gene            4450..5664
                     /gene="floR"
                     /locus_tag="D9K49_RS25055"
                     /old_locus_tag="D9K49_25055"
     ARG             4451..5661
                     /name="floR"
                     /gene="floR"
                     /gene_name="chloramphenicol/florfenicol efflux MFS
                     transporter FloR"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     gene            5692..5997
                     /locus_tag="D9K49_RS25060"
                     /old_locus_tag="D9K49_25060"
     CDS             5692..5997
                     /locus_tag="D9K49_RS25060"
                     /old_locus_tag="D9K49_25060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_001255015.1"
                     /translation="MRRTNHRNLVNVGILSGRIPLISLVQFIAVAEHLNFRHAAKALGI
                     SQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAVKTAE"
                     /name="LysR family transcriptional regulator"
     gene            6109..>6297
                     /locus_tag="D9K49_RS25065"
                     /old_locus_tag="D9K49_25065"
                     /pseudo=""
     CDS             6109..>6297
                     /locus_tag="D9K49_RS25065"
                     /old_locus_tag="D9K49_25065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /name="IS91 family transposase"
     gene            complement(6264..7463)
                     /gene="tet(A)"
                     /locus_tag="D9K49_RS25070"
                     /old_locus_tag="D9K49_25070"
     ARG             complement(6268..7463)
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            7569..8219
                     /gene="tetR(A)"
                     /locus_tag="D9K49_RS25075"
                     /old_locus_tag="D9K49_25075"
     CDS             7569..8219
                     /gene="tetR(A)"
                     /locus_tag="D9K49_RS25075"
                     /old_locus_tag="D9K49_25075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /protein_id="WP_000164043.1"
                     /translation="MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHF
                     RNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHAGTR
                     PGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGDSDAGERGGTVE
                     QAPLSPLLRAAIDAFDEAGPDAAFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD"
                     /name="tetR(A)"
     gene            complement(8251..8493)
                     /locus_tag="D9K49_RS25080"
                     /old_locus_tag="D9K49_25080"
     CDS             complement(8251..8493)
                     /locus_tag="D9K49_RS25080"
                     /old_locus_tag="D9K49_25080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000844627.1"
                     /translation="MKTAALDLARERQAHEAGARTRATAHERTPQQERQKAAREAERGR
                     EAWTLGQGMKKPVAGCYGRLTRWKGGGDVVYMALL"
                     /name="transposase"
     gene            complement(8799..9635)
                     /locus_tag="D9K49_RS25090"
                     /old_locus_tag="D9K49_25090"
     CDS             complement(8799..9635)
                     /locus_tag="D9K49_RS25090"
                     /old_locus_tag="D9K49_25090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="WP_000480968.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKP
                     IEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIA
                     AELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNA
                     SELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIA
                     QMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY"
                     /name="aminoglycoside O-phosphotransferase APH(6)-Id"
     ARG             complement(9636..10054)
                     /name="APH(3'')-Ib"
                     /gene="APH(3'')-Ib"
                     /gene_name="APH(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="52.06"
     ARG             complement(9639..10438)
                     /name="aph(3'')-Ib"
                     /gene="aph(3'')-Ib"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3'')-Ib"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(10499..11314)
                     /gene="sul2"
                     /locus_tag="D9K49_RS25100"
                     /old_locus_tag="D9K49_25100"
     ARG             complement(10503..11314)
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11644..>11730
                     /locus_tag="D9K49_RS25825"
                     /pseudo=""
     CDS             11644..>11730
                     /locus_tag="D9K49_RS25825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954590.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /name="Arm DNA-binding domain-containing protein"
     gene            complement(12002..>12757)
                     /locus_tag="D9K49_RS25115"
                     /old_locus_tag="D9K49_25115"
                     /pseudo=""
     CDS             complement(12002..>12757)
                     /locus_tag="D9K49_RS25115"
                     /old_locus_tag="D9K49_25115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS5075 family transposase"
                     /name="IS110-like element IS5075 family transposase"
     gene            complement(12810..13514)
                     /locus_tag="D9K49_RS25120"
                     /old_locus_tag="D9K49_25120"
     CDS             complement(12810..13514)
                     /locus_tag="D9K49_RS25120"
                     /old_locus_tag="D9K49_25120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(13716..14504)
                     /locus_tag="D9K49_RS25125"
                     /old_locus_tag="D9K49_25125"
     CDS             complement(13716..14504)
                     /locus_tag="D9K49_RS25125"
                     /old_locus_tag="D9K49_25125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="WP_000503573.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKPD
                     SDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYPAR
                     RELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKEHFS
                     KALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPAEHRP
                     LICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
                     /name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
     ARG             complement(14636..15234)
                     /name="dfrA17"
                     /gene="dfrA17"
                     /gene_name="trimethoprim resistant dihydrofolate reductase
                     dfr"
                     /tool="rgi"
                     /drug_class="diaminopyrimidine antibiotic"
                     /identity="99.36"
                     /coverage="126.75"
     ARG             complement(14639..15108)
                     /name="dfrA17"
                     /gene="dfrA17"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            15266..16279
                     /gene="intI1"
                     /locus_tag="D9K49_RS25135"
                     /old_locus_tag="D9K49_25135"
     CDS             15266..16279
                     /gene="intI1"
                     /locus_tag="D9K49_RS25135"
                     /old_locus_tag="D9K49_25135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="WP_000845048.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFI
                     RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI
                     GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG
                     TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR
                     AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH
                     SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER"
                     /name="intI1"
     gene            <16482..16832
                     /locus_tag="D9K49_RS25145"
                     /old_locus_tag="D9K49_25145"
                     /pseudo=""
     CDS             <16482..16832
                     /locus_tag="D9K49_RS25145"
                     /old_locus_tag="D9K49_25145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004636771.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3330 domain-containing protein"
                     /name="DUF3330 domain-containing protein"
     gene            17008..17568
                     /locus_tag="D9K49_RS25150"
                     /old_locus_tag="D9K49_25150"
     CDS             17008..17568
                     /locus_tag="D9K49_RS25150"
                     /old_locus_tag="D9K49_25150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220837.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001161490.1"
                     /translation="MQGHRIGYVRVSSFDQNPERQLEQTQVSKVFTDKASGKDTQRPQL
                     EALLSFVREGDTVVVHSMDRLARNLDDLRRLVQKLTQRGVRIEFLKEGLVFTGEDSPMA
                     NLMLSVMGAFAEFERALIRERQREGIALAKQRGAYRGRKKALSDEQAATLRQRATAGEP
                     KAQLAREFNISRETLYQYLRTDD"
                     /name="recombinase family protein"
     gene            17572..>19896
                     /locus_tag="D9K49_RS25155"
                     /old_locus_tag="D9K49_25155"
                     /pseudo=""
     CDS             17572..>19896
                     /locus_tag="D9K49_RS25155"
                     /old_locus_tag="D9K49_25155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /name="Tn3-like element TnAs1 family transposase"
     ARG             complement(8803..9635)
                     /name="aph(6)-Id"
                     /gene="aph(6)-Id"
                     /gene_name="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(13720..14504)
                     /name="aadA5"
                     /gene="aadA5"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
ORIGIN
        1 gtaagcagag tttttgaaat gtaaggcctt tgaataagac aaaaggctgc ctcatcgcta
       61 actttgcaac agtgccgcgc gacgagcagc agcaccagga gcagaagcac gtcgagaaaa
      121 agcaacagca gatcgagcag cgcccacggc gggccgctcg catcggataa gtcgaaaaat
      181 ccggctaaag tggccgagct gcacatcagg ccgcgcggtt ttcctccctg atcgccggcg
      241 cggtttcttc ctccctgaac cgcatgcaga cttgccgcct cggacacccc gaggcggttt
      301 tttttcgcct cgctcgagca tcgccgcatc cgacgatgcc gagacgacca ggccgcgcac
      361 gtcgagctgc agcatcgcca ttgccgacga tggcaccagg tcgccggcgg tggccaccga
      421 cctcgagctc gcatcgccac atccgacgat gcgcgccggc gtcgaccatc gccaggtctg
      481 acgatggcgg ccgccctgcc ctggatctcg catcgccatt tctggcgatg agatccacgg
      541 agcggccatt tagacccgcc aataacgacc cggccaagat aaatcgcatg acggcctttt
      601 tggccggggg tagcatgacc ggacactttg cgtatgccca aaggagcccg caagtatgcg
      661 caggacgaag ccagtagccg cgccgatggt ggcgcgggtc tatctgcgcg tcagcaccga
      721 cgcgcaggac ttggaacgcc aagaggcgat cactacggcc gcgaaggccg ccggctacta
      781 cgtcgccggc atctaccgtg agaaggcatc cggcgcacgc gccgaccggc ctgagctgct
      841 gcgcatgatc ggcgacctac agcccggcga ggtggtcatt gccgagaaga tcgaccgcat
      901 cagccgccta cctttgcccg aggccgagcg cctggtggcc tcgatacagg ccaaaggcgc
      961 aagcctggcc gtccctggcg tggtcgatct atccgacctg gcggccgagg cccagggcgt
     1021 cgccaagatc gtgctggaag ccgtgcagat catgcttttt cgcctggcct tgcagatggc
     1081 ccgcgacgac tacgaggaca ggcgcgaacg ccagcgccaa ggcattgagt tggcccgcca
     1141 ggccgggcgg tacaagggcc gccgtgctga tccgaagcgc cgcgcccaag ttgtcgcgct
     1201 gcgcaagtcc ggctacagca tcaacaagac cgccgagctg gccgggtaca gtgcggccca
     1261 ggtgaaacgg atatgggccg aggtcagcca ggccgaagcg aagcagcacg gcgcgttcgt
     1321 ggaggacgca ttgacggaag ccgatgccct ggccgctgtc ggccaggatg agcgccagga
     1381 ggaaagggca tgaagaagcc gaaccaagac gacgagccgt ttttcatcac cgaggagatt
     1441 gcggccgaaa tgatcgccgg cggctatgag ttcgagctgc cgcccattcc ttgcaccatc
     1501 cgcctacgcg acgtgctgga gcgcatgacc gatgctgagc tagcattgca gccgggcgag
     1561 atcgccgacc aggagcgtga acgctgccgg cgcaagccgt gttcaacctc atgatctggt
     1621 catggtattt ttcatggcac tgagcctgat agttcttgca aattgttgtc actaaagggt
     1681 tttgtgtgct tgtttacaat cgagtgggag tgacgggcac tggctggcaa tgtctagcaa
     1741 cggcaggcat ttcggctgag ggtaaaagaa ctttccgcta agcgatagac tgtatgtaaa
     1801 cacagtattg caaggacgcg gaacatgcct catgtggcgg ccaggacggc cagccgggat
     1861 cgggatactg gtcgttacca gagccaccga cccgagcaaa cccttctcta tcagatcgtt
     1921 gacgagtatt acccggcatt cgctgcgctt atggcagagc agggaaagga attgccgggc
     1981 tatgtgcaac gggaatttga agaatttctc caatgcgggc ggctggagca tggctttcta
     2041 cgggttcgct gcgagtcttg ccacgccgag cacctggtcg ctttcagctg taagcgtcgc
     2101 ggtttctgcc cgagctgtgg ggcgcggcgg atggccgaaa gtgccgcctt gctggttgat
     2161 gaagtactgc ctgaacaacc catgcgtcag tgggtgttga gcttcccgtt tcagctgcgt
     2221 ttcctgtttg ccagccggcc cgagatcatg gggtgggtgc tgggcatcgt ttaccgcgtc
     2281 attgccacgc acctggtcaa gaaagcgggc catacccacc aagtggccaa gacgggcgcg
     2341 gtcaccctga tccagcgttt tggatcggcg ctcaatctga atgttcactt ccacatgctg
     2401 tttctcgacg gtgtgtatgt cgagcaatcc cacggctcag cgcgtttccg ctgggtcaag
     2461 gcgccgacca gcccagagct cacccagctg acgcacacca tcgcccaccg ggtgggtcgc
     2521 tatctggaac ggcaaggcct gctggaacgg gatgtcgaaa acagctatct ggcctcggat
     2581 gcggtggatg acgacccgat gacacccctg ctggggcact cgatcactta ccgtatcgct
     2641 gtcggttcac aggcggggcg aaaggtgttc actttgcaaa ctctgccgac cagtggtgat
     2701 ccgttcggtg acgggattgg caaggtagcc gggtccagcc tgcacgccgg cgtggcggcc
     2761 agggccgatg aacgcaagaa gctcgaacgg ctgtgccggt acatcagccg cccggcggta
     2821 tccgagaagc ggctgtcgtt aacacgaggc ggcaacgtgc gctaccagct caagacgccg
     2881 taccgggacg gcaccacgca cgtcattttc gaaccattgg atttcattgc aaggctggcc
     2941 gccctggtac cgaagcccag agtcaaccta acccgcttcc acggggtgtt cgcacccaac
     3001 agtcggcacc gggcgttggt cacgccggca aaacggggca ggggcaacaa ggtcagggtg
     3061 gctgatgaac cggcaacacc agcacaacgg cgagcgtcga tgacatgggc gcaacggctc
     3121 aagcgtgttt tcaatatcga catcgagacc tgcagcggct gcggcggcgc catgaaagtc
     3181 atcgcctgca ttgaagaccc tatagtgatc aagcagatcc ttgatcacct gaagcacaaa
     3241 gccgaaacca gcgggaccag ggcgttaccc gaaagccggg cgccaccggc tgagctgctc
     3301 ctgggtctgt ttgactgacg agcctgaagg ccaacgatac caatcaaaat gctgcgttca
     3361 cagcgccgcg gcagggatcc gccgtgctgg ttgtcggaaa aggagccgct agtgggaaag
     3421 aggagggtaa attttcagcg ttgctggctc cccgtcagcc ggattgggtt gcatcgcagg
     3481 ggtgtcgaaa gagtcaactg cggtccaaag ctgttggact tgggtgaaaa gggcgtttat
     3541 tcttcctata cgtgccgcgt tccaggcggc gactatgagg gctatgtcga tgcccatgtg
     3601 cgccggctgg aggcgctacg ccgggccggt atcgtcgagc ggatcgacgc cgaccaatgg
     3661 cgcatccccg atgatctggt cagccgtgcc gccgcccatg acgccggccg agacagtcag
     3721 gccagcgttc gcgtcctttc cccggtcgat ctgaacaaac agatcggatc ggacggcgcg
     3781 acctggctgg accggcggct gatccacggc gagacggccg accttgcgcc aaccggcttc
     3841 gggcaacaag tccgcgaagc catggaccag cgccgcgagc accatatcga acagggcgac
     3901 gccacccgca gccgggacag ccgcgtcttc taccggcgca accttctcgc catcctgcgg
     3961 gagcgcgagg tagccggcgt cggatcggat atggctttga gtaagggcct gccgttccgc
     4021 gccgccacgg acggcgagag cgtcagcggc aagtttaccg gaaccgtgca tctatcgagc
     4081 ggcaagttcg ccgtggtcga gaaatcccat gagttcaccc ttgtcccgtg gcggccgatc
     4141 atcgaccgcc aactcggccg cgaggttatg ggcatcgtgc agggcgggtc ggtgtcgtgg
     4201 cagttagggc ggcagagggg gctggaacgc tgagtgcgcc catgccgcat tgcgaagcaa
     4261 aagataatcg gataaaatgt agcaattcat attcgtaagc gtggagtaat cagatgggaa
     4321 attccaagtc agcagacaag taagccgcaa caaccagtat tgttgttgcg gcgctctgta
     4381 aggctagtct catctgattg ctgacgagca gacgtcgccc ggtattcctt aatcgagggt
     4441 tgattcgtca tgaccaccac acgccccgcg tgggcctata cgctgccggc agcactgctg
     4501 ctgatggctc ctttcgacat cctcgcttca ctggcgatgg atatttatct ccctgtcgtt
     4561 ccagcgatgc ccggcatcct gaacacgacg cccgctatga tccaactcac gttgagcctc
     4621 tatatggtga tgctcggcgt gggccaggtg atttttggtc cgctctcaga cagaatcggg
     4681 cgacggccaa ttctacttgc gggcgcaacg gctttcgtca ttgcgtctct gggagcagct
     4741 tggtcttcaa ctgcaccggc ctttgtcgct ttccgtctac ttcaagcagt gggcgcgtcg
     4801 gccatgctgg tggcgacgtt cgcgacggtt cgcgacgttt atgccaaccg tcctgagggt
     4861 gtcgtcatct acggcctttt cagttcgatg ctggcgttcg tgcctgcgct cggccctatc
     4921 gccggagcat tgatcggcga gttcttggga tggcaggcga tattcattac tttggctata
     4981 ctggcgatgc tcgcactcct aaatgcgggt ttcaggtggc acgaaacccg ccctctggat
     5041 caagtcaaga cgcgccgatc tgtcttgccg atcttcgcga gtccggcttt ttgggtttac
     5101 actgtcggct ttagcgccgg tatgggcacc tacttcgtct tcttctcgac ggctacccgt
     5161 gtgctcatag gccaagcgga atattccgag atcggattca gctttgcctt cgccactgtc
     5221 gcgcttgtaa tgatcgtgac aacccgtttc gcgaagtcct ttgtcgccag atggggcatc
     5281 gcaggatgcg tggcgcgtgg gatggcgttg cttgtttgcg gagcggtcct gttggggatc
     5341 ggcgaacttt acggctcgcc gtcattcctc accttcatcc taccgatgtg ggttgtcgcg
     5401 gtcggtattg tcttcacggt gtccgttacc gcgaacggcg ctttggcaga gttcgacgac
     5461 atcgcgggat cagcggtcgc gttctacttc tgcgttcaaa gcctgatagt cagcattgtc
     5521 gggacattgg cggtggcact tttaaacggt gacacagcgt ggcccgtgat ctgttacgcc
     5581 acggcgatgg cggtactggt ttcgttgggg ctggtgctcc ttcggctccg tggggctgcc
     5641 accgagaagt cgccagtcgt ctaaccgacg actggtagca ggcccgctcc gatgcggcgc
     5701 actaaccatc gaaacctcgt gaatgtcggt atcctgtctg gcaggatacc gctcatttcc
     5761 cttgttcagt tcatcgccgt cgccgagcat ctgaattttc ggcatgcggc caaggcactt
     5821 ggtatcagcc agtcgagcgt cagcgcgcgt gtgaaagcgc tggaggataa ccttggtgtc
     5881 ctgctatttg agcgccatgc gcggggcgtt cggctaacag acgcaggcag gcacttcatg
     5941 gagcgtgtca cggcgggtgt cgatcaactc gatcacgcag tgaagaccgc ggagtgacgg
     6001 gcactggctg gcaatgtcta gcaacggcag gcatttcggc tgagggtaaa agaactttcc
     6061 gctaagcgat agactgtatg taaacacagt attgcaagga cgcggaacat gcctcatgtg
     6121 gcggccagga cggccagccg ggatcgggat actggtcgtt accagagcca ccgacccgag
     6181 caaacccttc tctatcagat cgttgacgag tattacccgg cattcgctgc gcttatggca
     6241 gagcagggaa aggaattgcc gggctatgtg caacgggaat ttgaagaatt tctccaaagc
     6301 ccgcgacgca gcgccggcag gcagagcaag tagagggcag cgcctgcaat ccatgcccac
     6361 ccgttccacg ttgttataga agccgcatag atcgccgtga agaggagggg tccgacgatc
     6421 gaggtcaggc tggtgagcgc cgccagtgag ccttgcagct gcccctgacg ttcctcatcc
     6481 acctgcctgg acaacattgc ttgcagcgcc ggcattccga tgccacccga agcaagcagg
     6541 accatgatcg ggaacgccat ccatccccgt gtcgcgaagg caagcaggat gtagcctgtg
     6601 ccgtcggcaa tcattccgag catgagtgcc cgcctttcgc cgagccgggc ggctacaggg
     6661 ccggtgatca ttgcctgggc gagtgaatgc agaatgccaa atgcggcaag cgaaatgccg
     6721 atcgtggtcg cgtcccagtg aaagcgatcc tcgccgaaaa tgacccaaag cgcggccggc
     6781 acctgtccga caagttgcat gatgaagaag accgccatca gggcggcgac gacggtcatg
     6841 ccccgggccc accggaacga agcgagcggg ttgagagcct cccggcgtaa cggccggcgt
     6901 tcgcctttgt gcgactccgg caaaaggaaa cagcccgtca ggaaattgag gccgttcaag
     6961 gctgccgcgg cgaagaacgg agcgtggggg gagaaaccgc ccatcagccc accgagcaca
     7021 ggtcccgcga ccatcccgaa cccgaaacag gcgctcatga agccgaagtg ccgcgcgcgc
     7081 tcatcgccat cagtgatatc ggcaatataa gcgccggcta ccgccccagt cgccccggtg
     7141 atgccggcca cgatccgccc gatatagaga acccaaagga aaggcgccgt cgccatgatg
     7201 gcgtagtcga cagcagcgcc ggccagcgag acgagcaaga ccggccgccg cccgaaacga
     7261 tccgacagcg cgcccagcac aggtgcgcag gcaaattgca tcaacgcata cagcgccagc
     7321 agaatgccat agtgggcggt gacgtcgttc gagtgaacca gatcgcgcag gaggcccggc
     7381 agcaccggca taatcaggcc gatgccgaca gcgtcgagcg cgacagtgct cagaattacg
     7441 atcaggggtc tgttgggttt cacgtctggc ctccggacca gcctccgctg gtccgattga
     7501 acgcgcggat tctttatcac tgataagttg gtggacatat tatgtttatc agtgataaag
     7561 tgtcaagcat gacaaagttg cagccgaata cagtgatccg tgccgccctg gacctgttga
     7621 acgaggtcgg cgtagacggt ctgacgacac gcaaactggc ggaacggttg ggggttcagc
     7681 agccggcgct ttactggcac ttcaggaaca agcgggcgct gctcgacgca ctggccgaag
     7741 ccatgctggc ggagaatcat acgcattcgg tgccgagagc cgacgacgac tggcgctcat
     7801 ttctgatcgg gaatgcccgc agcttcaggc aggcgctgct cgcctaccgc gatggcgcgc
     7861 gcatccatgc cggcacgcga ccgggcgcac cgcagatgga aacggccgac gcgcagcttc
     7921 gcttcctctg cgaggcgggt ttttcggccg gggacgccgt caatgcgctg atgacaatca
     7981 gctacttcac tgttggggcc gtgcttgagg agcaggccgg cgacagcgat gccggcgagc
     8041 gcggcggcac cgttgaacag gctccgctct cgccgctgtt gcgggccgcg atagacgcct
     8101 tcgacgaagc cggtccggac gcagcgttcg agcagggact cgcggtgatt gtcgatggat
     8161 tggcgaaaag gaggctcgtt gtcaggaacg ttgaaggacc gagaaagggt gacgattgat
     8221 caggaccgct gccggagcgc aacccactca ctacagcaga gccatgtaga caacatcccc
     8281 tccccctttc caccgcgtca gacgcccgta gcagcccgct acgggctttt tcatgccctg
     8341 ccctagcgtc caagcctcac ggccgcgctc ggcctctctg gcggccttct ggcgctcctg
     8401 ctgcggcgtc cgctcgtggg ccgtggcgcg ggtccgcgcg ccggcctcgt gcgcctggcg
     8461 ctcgcgggcg aggtccaggg cggccgtctt cacgttctgc cttgcgcaga tgagatagat
     8521 ctagcgtgga ctcaaggctc tcgcgaatgg ctcgcgttgg aaactttcat tgacacttga
     8581 ggggcaccgc agggaaattc tcgtccttgc gagaaccggc tatgtcgtgc tgcgcatcga
     8641 gcctgcgccc ttggcttgtc tcgcccctct ccgcgtcgct acggggcttc caggggtcgt
     8701 ttgcgggaag gggcggaatc ctacgctaag gctttggcca gcgatattct ccggtgagat
     8761 tgatgtgttc ccaggggata ggagaagtcg cttgatatct agtatgacgt ctgtcgcacc
     8821 tgcttgatcg cggccgcgat agctagatcg cgttgctcct cttctccatc cgcgttccaa
     8881 gctgcggaaa ggcacccata agcgtacgcc tggtcgagca ggcgacgcgg atcgacgtcc
     8941 agcgcacgag agaatgcgtc cgccatctgt gcaatgcgtc taggatcgag acaaaggtcg
     9001 tctctgtcag ccggatcgta gaacatattg gcggcgccaa agcccacttc accgaccaga
     9061 ccgacgggat ctatcaccag ccagccgcga ctggagaaca tgatgttttc atgatgcaga
     9121 tcgccatgta gcccacgcag ttccgaggca ttgctcatca tttgatcggc tataatcgcc
     9181 gcgtggacgt agtcagtttg acaacctgcg ttttgatcat cgcgcgcccg ctgaaacaaa
     9241 gctgcaaagc gatcccggat cgggagaagg gcagaaggca ggggttcctc agatgcggca
     9301 tacagcttcg ccattagttc cgctgcaatt tcggtcgcct ggtagtcgcc gtgctcggca
     9361 acgatgtgag agagcattcg ctccccggca tattcgagca acatcagatt gttctcacga
     9421 ccgagcaacc ggactgctcc cctcccattg cgccatacca gatagtcggc cccgcgcagt
     9481 tcatcagcaa tgtcttctat aggtttcaat cccttgacga ttgcaggagt cccgtctggc
     9541 aatgaaactt tccaaacgag gctggaaaag gtgtccgcaa tgagaacagg ttgcgaaacg
     9601 tgccaatgag caggaaaaac aggcggcatg aacatcaacc ccaagtcaga gggtccaatc
     9661 gcagatagaa ggcaaggcgt tcgcggtcgg gggcttcgat ccccaataca ttgaatagga
     9721 cagcgaaggc gcgctctgct tcatctggcg ctgcccagtt ctcttcggcg ttagcaatca
     9781 tgagtgccaa atcggcatag cgatctgctg ttccgagccg cccaaggtcg atcagacccg
     9841 tgcattgaag agttttaggg tccaccatga agttcggcat gcagggatca ccatggcaaa
     9901 caaccatatc ggtgcgctct tggtcgagcc gcaccggtag ctctcgttcg acacgagcca
     9961 aaagatcgag ctgcggcgta ctcttgtcct cgtccggtaa gaagtcggga ttgacggcat
    10021 tgcgggacac cacatcaacg gcgcgtccga acattcgcga cagcctgcgc tcaaacggac
    10081 attgatcaac cgataggctg tgaacagcgc caagttgctg ccccattgac ggccacgctt
    10141 tgagcaaatc cgctccagac agatcagccg ccggtactcc cggaattgcc gttatcacca
    10201 agcatgcacc ctcctgttcc tcctgccagt tgatgacctc ggggcaagcc acacctcgac
    10261 ctttgagcca aatgaggcgg tcacgctctc cagcgagctc accgcggcgg gaagcaggtg
    10321 cgattttcgc gaaggcatgc ccgtcaccac gtcgaaaaac aaaatcacca gattctccgc
    10381 ctctgacagg caaccagtca gaatgcgatt caccaaaaaa aatattagtt cgattcaatg
    10441 gaggttcctt cagttttctg atgaagcgcg aatatagaga aatatcccga atgtgcagtt
    10501 aacgaattct tgcggtttct ttcagcgccg ccaataccgc cagcccgtcg cgcaaggggc
    10561 gcggctcgtg tgtgcggatg aagtcagctc cacctgcggc ggcggcaagc tctgcagcga
    10621 gtgtcgcggc cccgacatcc cccggaccac ggcctgtgag cgcgcgcaga aaggatttgc
    10681 gcgaaacaga cagaagcacc ggcaaatcga agcgcagccg caattcatcg aaccgcgcca
    10741 gcaccgagag cgaggtttcg ggagcagccc ccagaaaaaa ccccatgccg ggatcaagga
    10801 caaggcggtt gcgtttgata ccggcacccg tcagcgccgc gatgcgcgcg tcaaagaacg
    10861 ccgcaatgtg atccatgatg tcgccagcgg gtgcctcgcg ccgatctgcc tgcccgtctt
    10921 gcaccgaatg cataacgacg agtttggcag atgatttcgc caattgcgga tagaacgcag
    10981 cgtctggaaa accgcgaata tcattgagat aggccacacc acgcgacaag gcataggctt
    11041 gcgtcgcggg ttgataactg tcgagcgaga cgggaatgcc atctgccttg agcgcgtcca
    11101 gcaccggcgc gatacgcgcg atttctgtgt cggacgaaac aggcgcggcg tcgggattgc
    11161 tggatgccgg accgaggtcg atcacatctg ccccctcggc catcagctta cgcgcctgcg
    11221 caatggctgc gtctggcgcc agataccggc ctccatcgga gaaactgtcc gaggttatgt
    11281 tgacgatgcc gaaaatgatg agcgatttat tcatgggggc ttctataata ataataatcg
    11341 agcatgagtc tcatacggat gctcgggtcg aaagggaatc cccaggcgag taacctgttt
    11401 gcggtgatcc attagctgca ggagcagaat agcatacatc tggaagcaaa gccaggaaag
    11461 cggcctatgg agctgtgcgg cagcgctcag taggcaattt ttcaaaatat tgttaagcct
    11521 tttctgagca tggtattttt catggtatta ccaattagca ggaaaataag ccattgaata
    11581 taaaagataa aaatgtcttg tttacaatag agtgggtatc ggagacgaag aaggacaagg
    11641 tacatgctga ccgataccaa gctgcgcaat ctcaagccca gggacaaact ctacaaagtg
    11701 aatgaccggg aaggtctcta tgtgggggtc gcctcagaaa acggaatcta tggtcactcc
    11761 cgtttttgca acaccgattt tgacgacaag ttggcttgct tgaatctatc cggcgtctga
    11821 atgggatttt attcccgcgc ctcgatgagt tccgcgcctg atgaacctcc agaaaatata
    11881 cggcttcaat gagcctttcc gttttacagg ttcctcaaca ggccggtggg ccgttagtat
    11941 catcaatatc agtattcgca aaaccagatg aatgattgtt taaactggtg tatttctgcc
    12001 tttatgcttc gtaagtttgc tgtcgcgccg tcagtgccca ggctattctg gccagcttgt
    12061 ttgccagagc acaggtgacg acaaagttgc ttttccgaca caacaactcc ctgacccagt
    12121 cggccaactt gccagactgg tgttccagtt tttgtatgaa taccctggca cactgaacca
    12181 acaaagttcg gatctttttg ttgccccgct tgctaatccc taacaatgtc gtccgacctc
    12241 ccgtgctgta ctgtcggggt accagccctg ttgccgccgc aaagtcacgg ctgctggcgt
    12301 actgcttccc gtcgccaatc tcagttgaaa tagtactggc agtcagcgtt ccaacgcagg
    12361 gaatactcag caagcgctgt ccaacctcat cttcgtccaa ctttcgtttc aactgagatt
    12421 ccagatcttt aatctgctca acaagatagt gataatgctg ttgtaatttc agcagtaact
    12481 ggctgagata aagaggcaaa ctactgtcct caagaagggt actcagtcga ctaataacgg
    12541 cagcacctcg cggaacgctg ataccaaatt ccagcagaaa agcatgcatc tgattagttg
    12601 ttttcacctt atcctgaacc agggattcac ggacacgatg cagagctcgc attgcctgct
    12661 gagattcggt tctgggctgc acgaaacgca tagatggacg tgatgctgct tcacagatag
    12721 cttcagcatc aacgaagtca tttttgttgc ttttaacggc actgttgcaa agttagcgat
    12781 gaggcagcct tttgtcttat tcaaaggcct tacatttcaa aaactctgct taccaggcgc
    12841 atttcgccca ggggatcacc ataataaaat gctgaggcct ggcctttgcg tagtgcacgc
    12901 atcacctcaa tacctttgat ggtggcgtaa gccgtcttca tggatttaaa tcccagcgtg
    12961 gcgccgatta tccgtttcag tttgccatga tcgcattcaa tcacgttgtt ccggtactta
    13021 atctgtcggt gttcaacgtc agacgggcac cggccttcgc gtttgagcag agcaagcgcg
    13081 cgaccatagg cgggcgcttt atccgtgttg atgaatcgcg ggatctgcca cttcttcacg
    13141 ttgttgagga ttttacccag aaaccggtat gcagctttgc tgttacgacg ggaggagaga
    13201 taaaaatcga cagtgcggcc ccggctgtcg acggcccggt acagatacgc ccagcggcca
    13261 ttgaccttca cgtaggtttc atccatgtgc cacgggcaaa gatcggaagg gttacgccag
    13321 taccagcgca gccgtttttc catttcaggc gcataacgct gaacccagcg gtaaatcgtg
    13381 gagtgatcga cattcactcc gcgttcagcc agcatctcct gcagctcacg gtaactgatg
    13441 ccgtatttgc agtaccagcg tacggcccac agaatgatgt cacgctgaaa atgccggcct
    13501 ttgaatgggt tcatgtgcag ctccatcagc aaaaggggat gataagttta tcaccaccga
    13561 ctatttgcaa cagtgccgat agtttggctg tgagcaatta tgtgcttagt gcatctaacg
    13621 catagttgag cggcgggcgc agcccgtccg cttgaacgcc gagttaggca tcagatgccc
    13681 tcggcgcggg tcgatgcact tttcgcacat gccgctcaac gcaagattct ctcaatcgtt
    13741 gctttggcat atcgaacgaa cgcggccgtc tcttcgacgc gcattgctag gtcgtcgtcc
    13801 tcgctaccca ggtacgccgc gcgtgccttg cagatgaggg gccgatgctc ggcaggcaaa
    13861 cgctccgata cccatgcggc agcaacgtcc ttaggagcaa tgagaccagt tgaagcgctg
    13921 taccaaatgc gagcaagagc aagaacgacg ttccgctcgt cacccttcca atccgactct
    13981 gcattccact gggcaatagt gtcgaaaagc gccttggaga aatgctcctt cggcaccggc
    14041 tcgaaaaacg tggctgcgga tgggcctaga agcgcaaggc tgtgttgcct cgccttggtc
    14101 agcaaaatcg caagatcgtg atccagaacg gcaggctcga acgttccgga aaggatgtcg
    14161 tggcggagcc actcaccgaa ctgaagctca cgccgcgccg gatagcgcca aggcactact
    14221 tcgcttcgag cgacaacagt tagctccagc ggtcgccatg ttccgccatc gcctggcggt
    14281 gatgagactt tcagcaaatc gagcattagc gcctgccgga gcgaatcgtt aggtgcggcg
    14341 ctgacggtca cgagcaagtc tatgtcgctg tccggcttca gccctccatc gatcgcagat
    14401 ccgaacaggt ggattgtgtc cagtgtcgca gccagatggc gctcgatcac cgcgcgagcg
    14461 tgggacagct gcttgaaaac ttgtgcaggg aaaaattcac ccatgatgcc taacgttaag
    14521 ttcagcggca gcttttaagt tgcggctttg tggaatactt ttgcgcagca aaaccacaaa
    14581 gacgcgactt aaaagctgtc caaggagcga agcgactggt gctgcaacgc attgttagcc
    14641 ttttttccaa atctggtatg tataatttat attagacata aaaaactgtt caaaaaccaa
    14701 attgaaattc tcaggcatta tagggaattt gatatcacct tcgacttcaa cgtgaacagt
    14761 agacaaatga attatatctg ctttttcaat aaggctatta tagatttgac ccccgccaga
    14821 gacatataca tgatctgtaa cttttgatag ctctttcaaa gcattttcta ttgaaggaaa
    14881 aactaggacg ttttcatttg agcttgaaat tccgttcttt gacactactg catatttgcg
    14941 atttggaaga acacccatag agtcaaatgt ttttcttccg acaaggagcc attgattata
    15001 tgtgagcgct ttaaagagta gttgctcacc ttttactgac cacgggatat caggaccact
    15061 accgattacg ccattttctg acactgcaga aatcaatgat attttcaatt taactccctt
    15121 aatggctaac tttgttttag ggcgactgcc ctgctgcgta acatcgttgc tgctccataa
    15181 catcaaacat cgacccacgg cgtaacgcgc ttgctgcttg gatgcccgag gcatagactg
    15241 tacaaaaaaa cagtcataac aagccatgaa aaccgccact gcgccgttac caccgctgcg
    15301 ttcggtcaag gttctggacc agttgcgtga gcgcatacgc tacttgcatt acagtttacg
    15361 aaccgaacag gcttatgtcc actgggttcg tgccttcatc cgtttccacg gtgtgcgtca
    15421 cccggcaacc ttgggcagca gcgaagtcga ggcatttctg tcctggctgg cgaacgagcg
    15481 caaggtttcg gtctccacgc atcgtcaggc attggcggcc ttgctgttct tctacggcaa
    15541 ggtgctgtgc acggatctgc cctggcttca ggagatcgga agacctcggc cgtcgcggcg
    15601 cttgccggtg gtgctgaccc cggatgaagt ggttcgcatc ctcggttttc tggaaggcga
    15661 gcatcgtttg ttcgcccagc ttctgtatgg aacgggcatg cggatcagtg agggtttgca
    15721 actgcgggtc aaggatctgg atttcgatca cggcacgatc atcgtgcggg agggcaaggg
    15781 ctccaaggat cgggccttga tgttacccga gagcttggca cccagcctgc gcgagcagct
    15841 gtcgcgtgca cgggcatggt ggctgaagga ccaggccgag ggccgcagcg gcgttgcgct
    15901 tcccgacgcc cttgagcgga agtatccgcg cgccgggcat tcctggccgt ggttctgggt
    15961 ttttgcgcag cacacgcatt cgaccgatcc acggagcggt gtcgtgcgtc gccatcacat
    16021 gtatgaccag acctttcagc gcgccttcaa acgtgccgta gaacaagcag gcatcacgaa
    16081 gcccgccaca ccgcacaccc tccgccactc gttcgcgacg gccttgctcc gcagcggtta
    16141 cgacattcga accgtgcagg atctgctcgg ccattccgac gtctctacga cgatgattta
    16201 cacgcatgtg ctgaaagttg gcggtgccgg agtgcgctca ccgcttgatg cgctgccgcc
    16261 cctcactagt gagaggtagg gcagcgcaag tcaatcctgg cggattcact acccctgcgc
    16321 gaaggccatc ggtgccgcat cgaacggccg gttgcggaaa gtcctccctg cgtccgctga
    16381 tggccggcag cagcccgtcg ttgcctgatg gatccaaccc ctccgctgct atagtgcagt
    16441 cggcttctga cgttcagtgc agccgtcttc tgaaaacgac aatggaggtg gtagccgagg
    16501 gtgtggaaac acccgactgc cttgcgtggt tgcggcaggc gggttgcgac acggtgcagg
    16561 gtttcctgtt cgccaggccg atgccggcgg cggccttcgt cggcttcgtc aaccaatgga
    16621 ggaacaccac catgaacgcc aatgaaccga gcaccagttg ctgcgtgtgc tgcaaggaaa
    16681 tcccgctcga tgccgccttc acgccggaag gggccgagta cgtggagcat ttctgcgggc
    16741 tggagtgcta tcagcgcttc caggcgcggg ccagcactgc gaccgaaacc agcgtcaaac
    16801 cggacgcttg tgattcgccg ccgtcaggtt gaggcatacc ctaacttgat gtcaggcagg
    16861 gccgcgccgc ttcgtcagaa tagagtctgc tttcccattt tttgacacat gcccgcgaag
    16921 gttatagatt tcagcctgac agaaatgggc tttgaggcac aacggaacag aaagtgcact
    16981 taagccgcct tcaaccaagg agacatcgtg caggggcacc gcatcggcta cgtccgggtc
    17041 agcagctttg accagaaccc ggaacgccag ctggaacaaa cccaggtgag caaggtgttc
    17101 accgacaagg catcgggcaa ggacacccag cgcccccagc tcgaagcgct gctgagcttc
    17161 gtccgcgaag gcgatacagt ggtggtgcac agcatggatc ggctggcccg caacctcgat
    17221 gacctgcgtc gcttggtaca gaagctgact cagcgcggcg tgcgcatcga gttcctgaag
    17281 gagggcctgg tgttcactgg cgaggactcg ccgatggcca acctgatgct gtcggtgatg
    17341 ggggccttcg ctgagttcga gcgcgccctg atccgcgagc ggcagcgtga gggcatcgcc
    17401 ttggccaagc agcgtggcgc gtaccggggc cgcaagaaag ccctgtccga tgagcaggct
    17461 gctaccctgc ggcagcgagc gacggccggc gagcccaagg cgcagcttgc ccgcgagttc
    17521 aacatcagcc gggaaaccct ctaccagtac ctccgcacgg acgactgaca catgccgcgt
    17581 cgcttgatcc tctcggccac ggagcgggac accctgcttg cgctgccgga aagccaggat
    17641 gacctgatcc gctactacac cttcaacgac tccgacctgt cgctgatccg ccagcgacgc
    17701 ggcgacgcca accgcctcgg cttcgccgtg cagctctgcc tgctgcgcta ccccggttac
    17761 gcgctgggaa ccgacagcga gctgcccgag ccggtcatcc tgtgggtggc gaagcaagtc
    17821 caggccgagc cggcgagctg ggcaaagtac ggcgagcgcg acgtgacccg tcgcgagcat
    17881 gcccaggaac tgcgcaccta cctgcaactg gccccgttcg gcctgtccga cttccgcgcc
    17941 ctggtgcgcg agctaaccga gctggcccag cagaccgaca aaggcttgct gctggccggt
    18001 caggccctgg agagcctacg gcagaaacga cgcatcctgc cggcgctgag cgtgattgac
    18061 cgggcctgct cggaagccat tgcgcgagcc aatcggcggg tctaccgcgc cctggtcgaa
    18121 ccactcacgg actcgcatcg ggccaagctg gacgagctgt tgaagctcaa ggccggcagc
    18181 agcatcacct ggttgacctg gctgcgccag gcaccgctga aacccaactc tcggcacatg
    18241 ctggaacaca tcgagcggct gaagacattt cagttggtgg acttgcccga aggcctgggc
    18301 cggcacatcc accagaaccg cctgctcaag ctggcccgcg agggtgggca gatgacgccc
    18361 aaagacctcg gtaagttcga gccgcagcgc cgctacgcga ccctggccgc cgtggtgctg
    18421 gagagcaccg cgaccgtgat cgatgagctg gtcgatctgc atgaccgcat cctggtcaag
    18481 ctgttcagcg gcgcgaagca caagcatcag cagcagttcc agaagcaggg caaggcgatc
    18541 aacgacaagg tgcgcctgta ctccaggatc ggccaggcgc tgctggaagc gaaggaaagc
    18601 ggcagcgacc cctatgccgc catcgaggcg gtgattccct gggacgagtt caccgagagc
    18661 gtcagcgagg ccgagctgct ggcccggccg gaaggcttcg accacctgca cctggtcggc
    18721 gagaacttcg ccaccctgcg ccgttacacg ccggccttgc tggaggtgct ggaactgcgc
    18781 gccgcgccgg ccgcgcaagg cgtgctggca gccgtgcaga ccctgcgtga gatgaacgcc
    18841 gacaacctgc gcaaggtgcc ggccgatgca cccacggcct tcatcaagcc gcgctggaag
    18901 ccgctggtga tcaccccgga aggcctcgac cggaaattct acgaaatctg cgccctgtcc
    18961 gagctgaaga acgccctgcg ctccggcgac atctgggtca agggctcgcg gcagttccgc
    19021 gacttcgacg actacctgct gccggccgag aagttcgccg cactcaagcg cgagcaggcc
    19081 ctgcccctgg cgatcaaccc gaacagcgac cagtacctgg aagagcgttt gcagctgctg
    19141 gacgagcagt tggccaccgt cacccgcctg gccaaggaca acgagctgcc cgatgccatc
    19201 ctcaccgagt cagggctgaa aatcaccccg ctggatgcgg cggtgccgga tcgggcgcag
    19261 gcgctgatcg accaaaccag ccagttactg ccgcgcatca agatcaccga actgctgatg
    19321 gacgtggacg actggacggg cttcagccgc cacttcaccc acttgaagga cggggccgag
    19381 gccaaagaca ggacgttgct gctgtccgca atcctcggtg atgcgatcaa cctcgggctg
    19441 accaagatgg ccgagtcgag ccccggcctg acctacgcca agctgtcctg gctgcaagcc
    19501 tggcacatcc gcgacgaaac ctattcggcg gccttggccg agctggtcaa ccaccagtat
    19561 cgccacgcct ttgccgccca ctggggcgac ggcacgacct catcctccga tggccagcgc
    19621 ttccgcgcgg gtggccgggg cgagagcacc gggcacgtca acccgaagta cggtagcgag
    19681 ccgggacggc tgttctatac ccatatctcc gaccagtacg cgccgttcag cacccgcgtg
    19741 gtgaatgtcg gcgtccgcga ttccacctat gtgctcgacg gcctgctgta ccacgagtcc
    19801 gacctgcgga tcgaggagca ctacaccgac acggccggct tcaccgatca cgtctttgcc
    19861 ctgatgcacc tgctaggctt ccgcttcgcg ccgcgca
//
