LOCUS       NZ_CP034798            42137 bp    DNA     linear   CON 18-JUN-2024
DEFINITION  Escherichia coli strain 08-3918 plasmid p08-3918-2.
ACCESSION   NZ_CP034798
VERSION     NZ_CP034798.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04504881
            Assembly: GCF_004010615.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42137)
  AUTHORS   Smith,P.A., Lindsey,R.L. and Strockbine,N.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-DEC-2018) EDLB, CDC, 1600 Clifton Road, Atlanta, GA
            30333, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 61.3X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004010615.1-RS_2024_06_18
            Annotation Date                   :: 06/18/2024 04:19:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,568
            CDSs (total)                      :: 5,435
            Genes (coding)                    :: 5,130
            CDSs (with protein)               :: 5,130
            Genes (RNA)                       :: 133
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 103
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 305
            CDSs (without protein)            :: 305
            Pseudo Genes (ambiguous residues) :: 0 of 305
            Pseudo Genes (frameshifted)       :: 112 of 305
            Pseudo Genes (incomplete)         :: 178 of 305
            Pseudo Genes (internal stop)      :: 64 of 305
            Pseudo Genes (multiple problems)  :: 39 of 305
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034798.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..42137
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="08-3918"
                     /serotype="O157:H7"
                     /db_xref="taxon:562"
                     /plasmid="p08-3918-2"
     gene            <1..366
                     /locus_tag="AYP37_RS28045"
     CDS             <1..366
                     /locus_tag="AYP37_RS28045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="WP_127835401.1"
                     /translation="EAINETKSKSKQAVFNMYLQNILEAKKYYTWEQIADYINNNTKTE
                     LAQKTYINMTERAKKRQKCSEPKEQAKTIDVIDQNEAKDDEPRGGVKGFFSNISESKKE
                     IEHDPSATNEKFINKYL"
                     /name="zinc transporter"
     gene            384..1136
                     /locus_tag="AYP37_RS28050"
     CDS             384..1136
                     /locus_tag="AYP37_RS28050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraL"
                     /protein_id="WP_127835402.1"
                     /translation="MKNSINFILQGKGGVGKSFVTAILAQYFIDENHMDNIVVGDTDPV
                     NTTTVKVKRLNADLIQITENSKVIQSKFDPMFESMLTNSQNTFVIDNGASTFLPLIQYF
                     NDNCVMDMFEDVEQDVYIHTVIVGGQALADTLQGFEELKELVKGSKVKLIVWINEFQGI
                     PALENIPLIETKFIEKNKDVIAGVVVIQDRKSDAFASDIKELTEKSLTLKEALESDHFG
                     LMAKSRLKRVFNDIYKQLDSIYDDEHGE"
                     /name="conjugal transfer protein TraL"
     gene            1138..1845
                     /locus_tag="AYP37_RS28055"
     CDS             1138..1845
                     /locus_tag="AYP37_RS28055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000108795.1"
                     /translation="MSTVNQPELKQPEKAVSSEDIDNFIVDVFKETGHKISKDDPVISL
                     IFLNQKIQEKFSNELQANFTALSEGFRQVVSSVENDYIQRFKNIVETCGDLDNEIKEKV
                     EEGKNDLKETSVEVKEKLTDDIIELISGIKRNQEKNNKLYEEKLKSLSKAVKPFSTRTA
                     IAICALCTLCLSAAFSGATWYVAQHEKEASLRFYARAFLDMKKITEESMRKLPKSDQQN
                     IKLKLEEIDSRKP"
                     /name="hypothetical protein"
     gene            1865..>2005
                     /locus_tag="AYP37_RS29165"
                     /pseudo=""
     CDS             1865..>2005
                     /locus_tag="AYP37_RS29165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311036.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            2314..2805
                     /locus_tag="AYP37_RS28065"
     CDS             2314..2805
                     /locus_tag="AYP37_RS28065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XF1762 family protein"
                     /protein_id="WP_021529587.1"
                     /translation="MQISPVTLRVAKAFISRHHRHNKPPVGHKFSIGLINDAGELIGVA
                     TAGRPVARHLDDGLTLEVNRTCTTGERNANSALYGAVWRAAKAMGYQRCITYTQADESG
                     ASLRAAGFVRVKELPPRKSWAESSVALRSKRDPVGNGGVPRVLWEIRRMSTTGIRIKGE
                     "
                     /name="XF1762 family protein"
     gene            2807..3070
                     /locus_tag="AYP37_RS28070"
     CDS             2807..3070
                     /locus_tag="AYP37_RS28070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000224227.1"
                     /translation="MATLTKKERAWLNELQDVLDRCPSPKKIGFYTIGDKSIYLYDLRR
                     MDEIMEALDNRSSMDWCVAVHDMNAGFDEKILFPSSVESTAG"
                     /name="hypothetical protein"
     gene            3081..3401
                     /locus_tag="AYP37_RS28075"
     CDS             3081..3401
                     /locus_tag="AYP37_RS28075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000206710.1"
                     /translation="MTTFTDKELIKEIKERIGSLDVRDNIERRAYEIALASLEAEAPNL
                     PGGFTIEEAKELHENLVKSHVSKALSGEKMKKENRDADLRWIHGVIVQAAWFVKASLGQ
                     NA"
                     /name="hypothetical protein"
     gene            complement(3532..3969)
                     /locus_tag="AYP37_RS28080"
     CDS             complement(3532..3969)
                     /locus_tag="AYP37_RS28080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000466318.1"
                     /translation="MFFSVGVETPKDDHTAYGITVPVFDCFDFGCVSAADSQAEIPAMA
                     REAILAIVEEMVISGAHSVDDIHDEGCLTYSANPNYNHCDSWFVIDVDLSEIEGKQQRI
                     NISLPDVLIRRIDGYVRESGGVYKDRSHFLAQAARHELAYK"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            complement(3994..4176)
                     /locus_tag="AYP37_RS28085"
     CDS             complement(3994..4176)
                     /locus_tag="AYP37_RS28085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833472.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000833470.1"
                     /translation="MKSADLLKELIAAGCELKRHKASSHQIWWSPITGKTFPVPHPKKD
                     LPLGTVRSIKKMAGI"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            4473..4916
                     /locus_tag="AYP37_RS29170"
     CDS             4473..4916
                     /locus_tag="AYP37_RS29170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000192626.1"
                     /translation="MTQLIPEKILEIIDDHDRAEKKQRNKIGFIYLCLCLAIIGVAAYT
                     FISTFSINVVTIIIMLFGVFMIVIFKSYLDSWSGIILSSDHILSILDKTKDYPEIKRIV
                     INRLLSGSILTGKDEEYIYSQLEKAQQSNEREKRLQAIKEYTS"
                     /name="hypothetical protein"
     gene            complement(5304..5582)
                     /locus_tag="AYP37_RS28095"
     CDS             complement(5304..5582)
                     /locus_tag="AYP37_RS28095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000545933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000545938.1"
                     /translation="MHFTTFLKKHFDIEKVVGTSDSGNDTESIYVYEKGNDCEPLFILH
                     ESWLNAEIKKCGVWTIGNIYSTLEHGKEYSEQELIKMIKEGKVISKY"
                     /name="hypothetical protein"
     gene            complement(6132..6383)
                     /locus_tag="AYP37_RS28110"
     CDS             complement(6132..6383)
                     /locus_tag="AYP37_RS28110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001132407.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin Xre-like helix-turn-helix
                     domain-containing protein"
                     /protein_id="WP_001132407.1"
                     /translation="MPNENTPENIKRLRQKIGLTQKECAEIFSMSPRTWRRKEEPVGTA
                     SGTALTPVEFKFLLLLAGEHPDYVLCKRNKKNSDSGSN"
                     /name="antitoxin Xre-like helix-turn-helix
                     domain-containing protein"
     gene            complement(6373..6633)
                     /locus_tag="AYP37_RS28115"
     CDS             complement(6373..6633)
                     /locus_tag="AYP37_RS28115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000702245.1"
                     /translation="MKIRKGDRQYYLNKEGDTFHLVKRVKTFSKSATLGKTKATVKTVA
                     DLVFHEEAFDTIDFASDGLRENDKEIVSMMIQEMSEGKNAK"
                     /name="hypothetical protein"
     gene            complement(6685..6909)
                     /locus_tag="AYP37_RS28120"
     CDS             complement(6685..6909)
                     /locus_tag="AYP37_RS28120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000814384.1"
                     /translation="MKQSTFPVIVSTTGHVFSVVRVTLCTICLKHEKTGEAYVVIFTDC
                     HNIRDYKKGVVPVLGELYQEDVDLITGKS"
                     /name="hypothetical protein"
     gene            complement(7007..7216)
                     /locus_tag="AYP37_RS28125"
     CDS             complement(7007..7216)
                     /locus_tag="AYP37_RS28125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020314678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000866037.1"
                     /translation="MKVLIGNINIDNYHMLSALAGIAGFDRSIQFTCEISASIEIMEDD
                     FVNKAGILKMLDEFIENDFSIKLV"
                     /name="hypothetical protein"
     gene            complement(7257..7580)
                     /locus_tag="AYP37_RS28130"
     CDS             complement(7257..7580)
                     /locus_tag="AYP37_RS28130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020314677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000432876.1"
                     /translation="MENYAKFVATEILNQLGGNRFIAMTGAKNFACFDENGECGLCFRL
                     PSNFAMKGINLVKIKLTFSDTYLVTFSRVRGATVKEISKFDNIYCDQLECLFNEQTGLA
                     TRL"
                     /name="hypothetical protein"
     gene            complement(8161..8490)
                     /locus_tag="AYP37_RS28140"
     CDS             complement(8161..8490)
                     /locus_tag="AYP37_RS28140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000855123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000855121.1"
                     /translation="MKTLTFNNGTVSVGDVFVSSWGYEQTNVNFYQVISVHGKKTVTVQ
                     EIRASVHRTHSMSGYKTPLLNDFCGEPLKRRVRDYYSTPAIEIESFETAYKGSPEEKHE
                     FTSYY"
                     /name="hypothetical protein"
     gene            9088..9753
                     /locus_tag="AYP37_RS28150"
     CDS             9088..9753
                     /locus_tag="AYP37_RS28150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000532148.1"
                     /translation="MGRALLVASDKGGVGKSTTATNLASYLVNNSRTVIILKTDKNNDI
                     LSWNEKRKQNGLLPVPVYEEYGDVSEVIKRLKKICEVLIIDCPGHDSKEFRSALTVADI
                     LLTLVKPSSDFEAETLTHVTEKVRTAQQINPDLQPWVLFTRINTTKPRHRKAAIDLDKL
                     LRENPVWIQPLRTRISDLDIFEAACNEGAGVHDVRRASSLSTAKAQIELLAQELGINP"
                     /name="division plane positioning ATPase MipZ"
     gene            9827..10111
                     /locus_tag="AYP37_RS28675"
     CDS             9827..10111
                     /locus_tag="AYP37_RS28675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001162371.1"
                     /translation="MALDLKTPVIPGQKTEQTNADTARFINEATRKKSGATKVTNVRLG
                     DVYEDILEREALRTGQTKTAIMKAALAAYEHGLDENGKNHWILQSARLK"
                     /name="hypothetical protein"
     gene            complement(10129..10725)
                     /locus_tag="AYP37_RS28160"
     CDS             complement(10129..10725)
                     /locus_tag="AYP37_RS28160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_000125164.1"
                     /translation="MTAIIEASMQPKKTPVIVVKKRRVLVMPENPVVNEKPQEVQKSAV
                     NENKKVQKKDAVAEKTHKKQPQPWYLKKQITFPPKYPKEYFEKCFNKVRAVFPELWTDE
                     KKNLPLKSGILQDVEKYLADNPDVDLTIEEWNCAVQVMTFRWQYLQNCTVPGATRYDLY
                     GKPAGTVKKAHATYAQLVLDARKKASEKKQLKRKG"
                     /name="ProQ/FINO family protein"
     gene            complement(10875..10997)
                     /locus_tag="AYP37_RS28165"
     CDS             complement(10875..10997)
                     /locus_tag="AYP37_RS28165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004118124.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="WP_223202818.1"
                     /translation="MVCCTLLIFTYLTRNRLCEVRLKDGNREVTASLAYESNGK"
                     /name="Hok/Gef family protein"
     gene            complement(<10942..11094)
                     /locus_tag="AYP37_RS29175"
                     /pseudo=""
     CDS             complement(<10942..11094)
                     /locus_tag="AYP37_RS29175"
                     /inference="COORDINATES: protein motif:HMM:NF010277.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5431 family protein"
                     /name="DUF5431 family protein"
     gene            complement(11230..11391)
                     /locus_tag="AYP37_RS28515"
     CDS             complement(11230..11391)
                     /locus_tag="AYP37_RS28515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001128311.1"
                     /translation="MPLIEYINKFYRGNQASFARLTGVQPAQVTQWINKGFIVVNHTLY
                     SPRRKLGI"
                     /name="hypothetical protein"
     gene            11975..12343
                     /locus_tag="AYP37_RS29180"
     CDS             11975..12343
                     /locus_tag="AYP37_RS29180"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223720106.1"
                     /translation="MAEYLQRFFVGGLEGLCFSLGRSSYARREAVGGTYILSGAALAAA
                     SEGIFVIIHSCFKDKYFPCGEATQGIKEQGLRIYCGFDVLCLLLSEVIPLRVFVDNRRR
                     FYSDTLLRPSKNCQSGTK"
                     /name="hypothetical protein"
     gene            complement(12441..13469)
                     /gene="repA"
                     /locus_tag="AYP37_RS28185"
     CDS             complement(12441..13469)
                     /gene="repA"
                     /locus_tag="AYP37_RS28185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001175215.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication initiator RepA"
                     /protein_id="WP_001175214.1"
                     /translation="MQLAVISKRHWSELSPEEQVRFWQDYEAGIESSFLVPQENKGGTT
                     KRRRGEHSTKPKCENPAWFRPDSYKALGGQLGHAYNRLVKKDPVTGQYTLRMHMSLHPF
                     YVLKRQSVGRKYKFRPEKERLLDAIWVVLVSFCDRGLHTIGMSVSRLAKEISPKDSKGN
                     VIPETAVTVSRLSRLLAEQVCFGALGTSEKTIWDRESRQRLPKYVWITETGWKMLGVDL
                     VKLQEQQRKRLAESEIRRQLIKEGVIREGEEISVHSARKRWYAQRSLDAIKSRREKAAK
                     RKRANRLAKLPHDEQRNEIARFILKRMPPDEAYWCTKERLEQLVARDLRQLELALTASP
                     PH"
                     /name="repA"
     gene            14603..15055
                     /locus_tag="AYP37_RS28190"
     CDS             14603..15055
                     /locus_tag="AYP37_RS28190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000101553.1"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiF/GrlA family transcriptional regulator"
                     /protein_id="WP_000101553.1"
                     /translation="MARKLKINPVIPECVADLKGYPLYIIVAYWGLRNNKTLTTTDVSR
                     NFLITQQQSYDVLTYIYQEAQKQITATKRTLFNEHKRRISAFRILDIDKGILRTPKKEI
                     AYASYDNIPTVTMKSTRCEIQDSFTELRRWMCSRKTGDRVEVFLNV"
                     /name="CaiF/GrlA family transcriptional regulator"
     gene            15048..15263
                     /locus_tag="AYP37_RS28195"
     CDS             15048..15263
                     /locus_tag="AYP37_RS28195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1187 family protein"
                     /protein_id="WP_000049866.1"
                     /translation="MSKYQINATIKKPGGGPVKWTHYSDFPMTAEECRKNFSKEKEAGK
                     CFSVDVHISDFICKEIPPQNAGNTYG"
                     /name="DUF1187 family protein"
     gene            15256..15432
                     /locus_tag="AYP37_RS28520"
     CDS             15256..15432
                     /locus_tag="AYP37_RS28520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000753050.1"
                     /translation="MADFGSTKQTVTFEEWHELLMDYAELRGGNAADAEAWRGDYEAGK
                     TPVEAYCDEWGED"
                     /name="hypothetical protein"
     gene            15459..16412
                     /locus_tag="AYP37_RS28200"
     CDS             15459..16412
                     /locus_tag="AYP37_RS28200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564242.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_072130394.1"
                     /translation="MVTSIPVLLLILVALIFVKSAVKIVPQGNAWTVERFGKYTHTLSP
                     GLHFLIPFMDRIGQRINMMETVLDVPKQEVISKDNANVTIDAVCFIQVIDAAKAAYEVD
                     NLASAISNLVMTNIRTVVGGMNLDDMLSQRDSINSKLLTVVDYATDPWGIKVTRIEIRD
                     VKPPEELTKAMNAQMKAERTKRAQILEAEGIRQSQILKAEGEKQSQILKAEGERQSAFL
                     QSEARERQAEAEARATKLVSDAIAEGDVQSVNYFIAQKYTEALQAIGTASNSKLVMMPL
                     DSSSLVSSVAGISELLKNVSQDTSKVDMKQAQQYLS"
                     /name="SPFH domain-containing protein"
     gene            16474..16917
                     /locus_tag="AYP37_RS28205"
     CDS             16474..16917
                     /locus_tag="AYP37_RS28205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964333.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="WP_001687695.1"
                     /translation="MFWFTLFLLCIALEIITGTGWLLVISLGALSSAIVDFFLPISQEA
                     NICFFASISILTSIIKFVYDKKHKKLDTPLVNTGHSRFKGKEFTLSDDIVNGKGQLLIG
                     DTFWPVETLHNENYPAGTRVIVTDMQGITLKVMTIEDKNENKE"
                     /name="NfeD family protein"
     gene            16921..17091
                     /locus_tag="AYP37_RS28525"
     CDS             16921..17091
                     /locus_tag="AYP37_RS28525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000550720.1"
                     /translation="MHLSLLIPLTGAAMNALCIFIIRLLDKDFIEAYKKTLKNITALHI
                     LLMVLSVTGIV"
                     /name="hypothetical protein"
     gene            17320..17547
                     /locus_tag="AYP37_RS28210"
     CDS             17320..17547
                     /locus_tag="AYP37_RS28210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001439337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_206614668.1"
                     /translation="MAVIWIIFFIGDRREKLKHAELDVIKIKARQKIYDRLRYVENEHI
                     VFDSVTGREVPAERTCINELVEALAMEATT"
                     /name="hypothetical protein"
     gene            17580..17837
                     /locus_tag="AYP37_RS28215"
     CDS             17580..17837
                     /locus_tag="AYP37_RS28215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001542015.1"
                     /translation="MYRKKHHLIKIFLLKMACNVFSFLLGAFILSAPFVLYTLTGSVLN
                     AVIHFTFSLPLATILLVYAYSGFEESIYLFMAYKYDSSKS"
                     /name="hypothetical protein"
     gene            17818..18120
                     /locus_tag="AYP37_RS28220"
     CDS             17818..18120
                     /locus_tag="AYP37_RS28220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001360345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001360345.1"
                     /translation="MTQAKANLRKLRRARYVPPRTVKKSIANTERVVSKAITGCGVFRD
                     IPQVKINLIETRKILQIELALSIANLSEANPIEIRKKIKSIDRQLSSTSKIRTTL"
                     /name="hypothetical protein"
     gene            18117..18374
                     /locus_tag="AYP37_RS28225"
     CDS             18117..18374
                     /locus_tag="AYP37_RS28225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000739144.1"
                     /translation="MKKNDDLITLPSHNSHALDYIIKKAFTPRKTKTSTATHNVYSYNK
                     EESTLNFQKIGEAIFFGTDLVIKLKPNISASGELFICQKD"
                     /name="hypothetical protein"
     gene            18378..19373
                     /locus_tag="AYP37_RS28230"
     CDS             18378..19373
                     /locus_tag="AYP37_RS28230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001028543.1"
                     /translation="MNIVSEFLEKVTTIVESTAATNAAKVAQAISPTFFAAIALYVIYL
                     IYEITYAQRDVLMSEVTKNIGAFALVGAFTYSAPYYSQFVIPFVMHAGSDLSAAVTGGS
                     GTATSVDNLWNMLSVTLNDFKNNELDTLEWYSFTDQLYIYLIWGVGYVGGLLLIYYTTV
                     FLTLSTFMVGILLSAGILFICFSLFASTRNMFSAWVGSCLNYILLNLFYSISFSFVISF
                     VEQTVPSSGNITLTTVVYFFMVTVISIFLVEQVGTLCSTLTGGVGINGLTSAANGFGGK
                     VASGFMRASGLRSFTNGFASKMPNPFFNAGSRSASALVQGLNRGSKLKAG"
                     /name="type IV secretion system protein"
     gene            19379..20020
                     /locus_tag="AYP37_RS28235"
     CDS             19379..20020
                     /locus_tag="AYP37_RS28235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001463086.1"
                     /translation="MKDKVLSFLFAGIITITSPSIFASGIPVVDVAAIAKTVEEGLNRA
                     AEAARQLEQLKQQYEQTIRYAEEQKKRLEGFTDFSNGFDSASSYMKDSLSTITNSAKSD
                     LSSLRSQYDLSSNVAETQQKYDAILAKIKFYENFNNEMQERAKRLTTLQKEFASADTPQ
                     KKADLSNQLNTEKLTMELQLKQYDIAERQLENERKAQYETYVRQKRRDLS"
                     /name="type IV secretion system protein"
     gene            20022..20276
                     /locus_tag="AYP37_RS28240"
     CDS             20022..20276
                     /locus_tag="AYP37_RS28240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_001043555.1"
                     /translation="MNKSRNAIIASSIIFASLMLVGCKEKIYSVEYYSNNISEATKTLE
                     DCKKGTITDQNCDNARAALQQKQDSEYKKKVSEMRRRLD"
                     /name="EexN family lipoprotein"
     gene            20429..21064
                     /locus_tag="AYP37_RS28245"
     CDS             20429..21064
                     /locus_tag="AYP37_RS28245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000835771.1"
                     /translation="MKSIILSMVAATALLSGCADSKTQPVPESPLTSNDHQITLKIDTV
                     RTDLPDSSPVCLNGMNIYESLSERHPGLFAKNQNVIFRSAFFDDGQAISSETIRKIMQS
                     TPCVESQTTSAGSWEPATELIPRQAISGDTTLAEKDRTAGFTMRIAPEIERGNFHLLLT
                     TTDPIRKQTVEQNILLKPDQPLIVSGFTGVNADSQSENRIVIITPHVR"
                     /name="hypothetical protein"
     gene            21131..21430
                     /locus_tag="AYP37_RS28250"
     CDS             21131..21430
                     /locus_tag="AYP37_RS28250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000835763.1"
                     /translation="MKSIILSMVAASAIALSAPVYASDPCASVLCLYGKAIGSGGGSEC
                     KSAEKDFFNIIKKKKGSIRWSKTFDARKAFLNQCTTADPAAISKIMSKFGRSWG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            21433..22668
                     /locus_tag="AYP37_RS28255"
     CDS             21433..22668
                     /locus_tag="AYP37_RS28255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin co-regulated pilus biosynthesis Q family
                     protein"
                     /protein_id="WP_000733393.1"
                     /translation="MKKLIIIPTTLLLNACSHAPEPAQAKGGWYELNTTIEQVRADTYY
                     NGVILQQPVSQPNSTVQYSNDNYLKKEAINVTPAPRIAETVKPRSEQSATAPKNQGSNN
                     SFLKPTTNSITSSGEIKTAAKGATEQHSEQPALPPAKPISSNNHQAQTAQNTDQQTKPR
                     PEQPPLMSKSGFLKKNANNAVPATTLTGPSTPEKQIYFVRHDGKGSLQKAVKEIVPSDW
                     TAEISPEVTKTFRRTISWQGNDQWPYVLDKMLRNYGLTVIKNTEKRHLLIDFQQQKGKT
                     SQKAPVSPDKTPASPVRTPVSSDKLPQKPLTPVTVPQKQTEKLTWNLKKGSTLRDGLTE
                     WASSSPCGNSTWNLVWDTPVNYRIDAPLIFRGNFESALKDTLMLYLSADKPLYAFRNIA
                     QCVITIKDTQQE"
                     /name="toxin co-regulated pilus biosynthesis Q family
                     protein"
     gene            22674..23111
                     /gene="pilM"
                     /locus_tag="AYP37_RS28260"
     CDS             22674..23111
                     /gene="pilM"
                     /locus_tag="AYP37_RS28260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilM"
                     /protein_id="WP_000539665.1"
                     /translation="MGWFFSLLLIFLSIGSYYLTDNNNQTIQRMKLLPAKQEAIEFVHF
                     ANVINDYLYKYPDKRNSGGTLTSEQIGITPVYDIHHIIYGKRVYIWSADTEGLMSALQQ
                     QTKHSAMLGRVKNKKIVDNQGNDMGVPVPSSIPEEAIVLIN"
                     /name="pilM"
     gene            23230..23628
                     /locus_tag="AYP37_RS28265"
     CDS             23230..23628
                     /locus_tag="AYP37_RS28265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001153669.1"
                     /translation="MQDNDDVSELDIATREVLILRCNLIQLASEYIKINPLKNTRIYTD
                     LIHRSADVIKNIEQGNIQNKHNYLSQDVKHTLVLYDLYKSDFEQCPGAKSLIPVREKIV
                     SLKELLSGANELDSIVRRPRRKKRSSRI"
                     /name="hypothetical protein"
     gene            23649..24233
                     /locus_tag="AYP37_RS28270"
     CDS             23649..24233
                     /locus_tag="AYP37_RS28270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_001177114.1"
                     /translation="MQLSAAVLAALISQCAPDVSPDTMNALIMTESGANPYVIANVSDG
                     TSKYFKDEKGAIEYAEKLTAENKRFSAGLTQIYSKNFPSLNLTNKTVFDPCTNIKAGAA
                     VLTDNYLRQKEGSSNQKILRALSLYYSGNESTGFIKEKKFNNTSYLERVIRNANNYIVP
                     SIREKTDESEIKPPNDEEKTSPDWDVFGDFS"
                     /name="lytic transglycosylase domain-containing protein"
     gene            24233..24523
                     /locus_tag="AYP37_RS28680"
     CDS             24233..24523
                     /locus_tag="AYP37_RS28680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001708011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000865478.1"
                     /translation="MKVKSTLQYFILAFFLSLTASVAYAGGLDTATNTMTELKTWAFGF
                     GGVCALCYLIYNIIMAFMEKKSWSDVGMALIYCSLAGGALYAGNWALELFK"
                     /name="TrbC/VirB2 family protein"
     gene            24594..24914
                     /locus_tag="AYP37_RS28280"
     CDS             24594..24914
                     /locus_tag="AYP37_RS28280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_000362081.1"
                     /translation="MDKVNEHVSESFMTYNGFNRPALVAGIPLMLLLFTAFFAVLTGFP
                     AIFLWGIKGIIIPVICALFLFIVKLACENDSNALRVIRLNLMGLLLKIRHRDLIIGYSS
                     VR"
                     /name="VirB3 family type IV secretion system protein"
     gene            24920..27277
                     /locus_tag="AYP37_RS28285"
     CDS             24920..27277
                     /locus_tag="AYP37_RS28285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="WP_000548953.1"
                     /translation="MHKIKLKNSDNMDVAREYPDYRFHITDSIIFTSDRKMLASLVVAG
                     IPFETENDNVLTNLFNSVKNFLIGLGKEGDLYLWTHLIKKRITIDGEWNFDNAFLSRFS
                     KKYLALFTSSAFYKSTWYLTFGIPYDDVDTGIERMNEMTQQAQKALQPFNASVLSVHNT
                     YISEVADYLSLLLNTEHNMIPLSSTPLSSSICDSEWYFGADVLELRNNESDSKKFATNY
                     ILKDFPIETTPGQWDFLLKQPYEFILTQSFIFESPTKTLKNIDSQLNKLQSANDAAKTQ
                     QEELEAGKEAVAAGITLFGSLHCALTVFGDTPDQARSNGIKLSAEFITSGKGFRFSRAS
                     LASPFVFFSHMPLNKRRPLDTRRTITNLACLMSFHNYSSGKKSGNPIGDGSAIMPLKTV
                     SDSIYWFNTHYSPPEKNVTGQKIAGHGMILGATGTGKTTFEAAASGFLQRFDPLMFVVD
                     FNRSTELFVRAYGGSYFTLQEGIYTGCNPWQLAEGPESPVWHRLLAFLKRWTQVLARDN
                     QGNPCSDEHGIELNAAVESIMRMPVEERRTALLLDIVSPELQTRLAKWCDNGEYAWAVD
                     SPRNTFNPLHHKKVGFDTTVVLDTKNGIHPACEPLLAVLFFYKEIMQRGGNLMLSIIEE
                     FWMPANFPMTQSMIKSALKAGRMKGEMMWLTSQSPEDAINCAIFAALVQQTATKILLPN
                     PDAKWEGYKEIGLTEKEFEKLKELTKESRTMLIKQSGSSVFAKMDLFGFDEFIPVLSGS
                     ETGLSIFDEIIAEKGDVAPDIWIPELLKRLNG"
                     /name="VirB4 family type IV secretion system protein"
     gene            27443..28177
                     /locus_tag="AYP37_RS28295"
     CDS             27443..28177
                     /locus_tag="AYP37_RS28295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_023155253.1"
                     /translation="MENTNYYEHSKKEATKKKFEEKNEKKDYFKAIRDFERSEIDIIKK
                     KAKTFTILAIGEFVVICILGFAIASLAPLKTAVPFLVRVDNSTGYTDIAPQLSDAKESY
                     QDVETKYFLSKYLINYEAYDWQTIQEQADTVKTMSSQKVFSAYDTMIRADSSPLNILKN
                     NYKIKVQINSVILLRKDMAQVRFKKMVLDLSGKPAPGYRATEWISTISFDWDKDIKTEK
                     ERLVNPLGLQVLSYQPDPEVIK"
                     /name="type IV secretion system protein"
     gene            28243..28944
                     /locus_tag="AYP37_RS28300"
     CDS             28243..28944
                     /locus_tag="AYP37_RS28300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_000274524.1"
                     /translation="MYGTPSERDGRIQTVDYNEQDVFNVRVKAGAQTTIKFGQDETIKD
                     VGIGDPEAWSVSVRDNTLFLRPKAEEPDTNVTVQTNKHIYPLYLISTTKQPTYILRFNY
                     PKPPSATVMTEKPFPCTDGGIINGHYQLKGDKSIFPYQVWDNGEFTCMRWTNKQEIPVL
                     YRVDADGNEHLVNGDRNKNTMVYYDVAENLRLRLGDQVADIRTSSIVNRPWNKKGTSNG
                     KTRVEKFSYEK"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            28934..30073
                     /locus_tag="AYP37_RS28305"
     CDS             28934..30073
                     /locus_tag="AYP37_RS28305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="WP_000790640.1"
                     /translation="MKNKDDEKNNDAGNRGIIEVKGKAAPKKILILIILLIAALFVIII
                     LFKVLSREQVVQQTPLEKSDETLVTNTNNGVSLTTMMKNIEEKEKLDAANRRKAQEEQE
                     QKQADNAPSAPASQKADQTAVNVIANGSPQTASGDPNQPQPLPKSVRQLMGDTMVKIDN
                     QEPGEKNQERDDLQGSQYADGKVSPVLNRRYLLSAGTALSCVLKTKIVTSYPGITMCQL
                     TRDVWSDNGEVLLARKGALLIGEQNKVMTQGVARVFVNWTTLKDENVNVRIGALGTDSL
                     GASGLPAWVDNHFGQRFGGALLLSLLGDGLDILKNSTQQTGSNSNITYENTSDATKEMA
                     KTTLDNTINIPPTAYINQGTVLSVIVPRNIDFSSVYELQ"
                     /name="TrbI/VirB10 family protein"
     gene            30092..31147
                     /gene="virB11"
                     /locus_tag="AYP37_RS28310"
     CDS             30092..31147
                     /gene="virB11"
                     /locus_tag="AYP37_RS28310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001708009.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_001059977.1"
                     /translation="MNNIRDTSNTSQPRDNSKTARRYLDMTGIQSVLNIEHVTEISVNK
                     PGTIWFEGKNGWESKDAPDATFDNLMTLAKTLTNLSKIKIPLSHDNPIASVVLPGGERG
                     QIIIPPATENNSVVISIRKPSLTRFTIDDYVRTGRFDNVRIATKHEAILTERQRYLYEL
                     SRRPDGQSKAQFLREAVKDRLNFLIVGGTGSGKTTIAKAIADIFPPERRYITVEDVPEM
                     SLPLHPNHIRLFYKKNTVEAKEIIEACMRLKPDHIFLAELRGNEAWSYLEALNTGHEGS
                     ISTIHANNTYASFSRLASIVKQSDVGMTVDMDLIMRTIKTSIDVILFFNHTRMTELYYE
                     PEEKNRFLSTM"
                     /name="virB11"
     gene            31163..33121
                     /locus_tag="AYP37_RS28315"
     CDS             31163..33121
                     /locus_tag="AYP37_RS28315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338972.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_127835403.1"
                     /translation="MDAKKTGGLILFLLLLLVGVLIASNYLGGYTALRYSSVDMSLLKW
                     DTFHSVISTFSGNPQYKKLVFMAWFGFSVPLIFFAIFMLIVVIGIMPKKVIYGDARLAT
                     DMDLSKSGFFPDKKSPYKHPPILIGKMFKGRYKKQFIYFAGQQFLILYAPTRSGKGVGI
                     VIPNCVNYPGSMVILDIKLENWFLSAGFRQKELGQKCFLFAPAGYAETIDQAIKGQIRS
                     HRWNPLDCVSRSDLLRETDLAKIAAILIPASDDPIWSDSARNLFVGLGLYLLDKERFHL
                     EQKAKGHNVPDVLVSISAILKTSVPDGGKDLAAWMGQEIENRSWISDKTKSFFFKFMSA
                     PDRTRGSIETNFSSPLSIFSNPITAEATNFSDFDIRDIRKKPMSIYLGLTPDALITHEK
                     IVNLFFSLLVNENCRELPEHNPDLKYQCLILLDEFTSMGKSEVIERAVGFTAGYNLRFM
                     FILQNEGQGQKSDMYGQEGWTTFTENSAVVLYYPPKSKNALAKKISEEIGVRDMKISKR
                     SISSGGGKGGSSRTRNDDVIERPVLLPEEIVSLRDKKNKTRNIAIREIITSEFSRPFIA
                     NKIIWFEEPEFKRRVDIARNNHVDIPNLFTQEVMDEIAKIAEIYLPKAGGKKVMVAGGN
                     VITNPDLDNHDKTDVSE"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            33172..34815
                     /locus_tag="AYP37_RS28320"
     CDS             33172..34815
                     /locus_tag="AYP37_RS28320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035590.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA];
                     GO:0009306 - protein secretion [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN family type IVB pilus formation outer
                     membrane protein"
                     /protein_id="WP_001035589.1"
                     /translation="MNKKLLCLLISSFLLSGCANFKKINANELAAERDAQKATEYAKKI
                     RNNPVIQDSTKQWINTTPIIEKQVKQSAPPCPIVINTRSDIELRQIAQRITQTCHIPVR
                     ISADVWTYLNGTGTGSTQQMTGSIPAPDANGMVPLASVGSQPVKVSSGGTSLPELNISG
                     LPALLQTVSSRLGISWKYDKGRITFFYLETRSFPITYMDSNVAYNSKVVSGTMSSSGST
                     GSTSSGGMTGDASNTQTTTVEMKSSLYNDLKSEVSSMLTPGTGRMYLSTGSLTVTDTPD
                     VLDSVQEIVNKRNNEMSRQVVLNVEILSIKKSSQEQAGIDWNAVFNDGHLGLSLGGSFG
                     DAAENVITSGVSIVDGKLAGSKAFLKALSSQGSVSVVTQNSAVTKNLTPVPMQIANQQG
                     FIESVTTDSTANVGSSTSLNAATITTGFNMTLLPYIQPDSQNLQLLFSMSLSDKPTFEV
                     FESGGSKAQTPNVDLKTINQTIDLKSGQTVILSGFQQSNRKTSKQGVITPSFFGLGGGV
                     NSEDGDTILVVLITPNVLNSGSSAVIKNVN"
                     /name="PilN family type IVB pilus formation outer membrane
                     protein"
     gene            34866..36176
                     /gene="pilO2"
                     /locus_tag="AYP37_RS28325"
     CDS             34866..36176
                     /gene="pilO2"
                     /locus_tag="AYP37_RS28325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001360347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4b pilus protein PilO2"
                     /protein_id="WP_024222069.1"
                     /translation="MSENNQNNQNFTSVIKNKRAFFSGLDWKTLPSEEKNARTFARKND
                     AEYFLSCQYQDSENETKTMVAFIRKEDLPTGASSFWSLALMIKPLIEPDGYAICELGDL
                     YGFVSCVNNVLVNDVVGNKSQIMSALTTFLEFNETPEPGWKLYQPESWDISQALPSLTL
                     SALIDVKKPPKEAAFTRVSRKRQFMIYGGSAILAILLWNGITMYQEYREKEAAAEAARL
                     RLAKEMADKQAIQIAPPWQHLPEIKPFIDKCIDKWDALPLSIAGWRFDLAECSTSGNDG
                     LLRTSYKELSGVTVEDFSTRIREIFQGTTTATFVLPEGSAGGFSLPVSFDVSPDPITPD
                     TLPQATDIQERLTTFAQKMRLKLTWQEIENTKTDEEGRPIILPWNEYELMIQTSTPPSI
                     LFANFHEPAVRFQYAGIKLEEGRLNYEIKGAFYVKNN"
                     /name="pilO2"
     gene            36160..36654
                     /gene="pilP"
                     /locus_tag="AYP37_RS28330"
     CDS             36160..36654
                     /gene="pilP"
                     /locus_tag="AYP37_RS28330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401690.1"
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilP"
                     /protein_id="WP_000912553.1"
                     /translation="MLKIIKPTIISVCFFSSLAYATESESTPKDEIKYSSPTILQVEQI
                     QAETVIYEAKLARQKAVSELRNLDLNGVASATPAITPSSGYSSLADTDIPAQRVAAKSL
                     RVIEIFGTPQQMSARISLLDGSVTDVKVGQSIPGTSYKVASITGNGVWIQNGTEKRQLI
                     L"
                     /name="pilP"
     gene            36679..38217
                     /locus_tag="AYP37_RS28335"
     CDS             36679..38217
                     /locus_tag="AYP37_RS28335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="WP_000466227.1"
                     /translation="MFFSDADYPGKDISDVVYVSISEKDDKPVQVYIADNSKGQRAVQA
                     YIGTLNVKYPGQVNITSTTLDVIASRYQDSEKRSDSNSSQHLNSNQEKVISYLAKANKL
                     GSSDLHITPGRDGSEFTYVEARVHGELEILDVIPRKEGLELLGAAYSGMSDVIKGTQFD
                     PAIPQDARIAENFLKPVNLFGARYSHYPCVGGVYAVFRLIKDDSEDIPTFEELGYMPQQ
                     IQTIRRMLQRPEGIIVLSGPTGSGKSTTLRTASEAYLSTFGFNHNDNMRLPRKRLFTIE
                     SPPEGRIPGAIQTAVRDSVDGWVDAIKSAMRLDPDAILNGEIRDHASALAAIKASMTGH
                     LLLTTLHANDALNIIERLEMENIQARLIADPLLFIGLLSQRLVQKLCPYCKRTYAEMAD
                     KLSTEERKLIEENCLPEQVRLRNLDGCEHCYKGVTGRTVIAEVVSPDARFFQLYRQSGR
                     LEAKSYWHYELGGITRNQHLLHLINHGLVDPLSAHFISPIDEDKYSMLPEGTWR"
                     /name="ATPase, T2SS/T4P/T4SS family"
     gene            38208..39317
                     /locus_tag="AYP37_RS28340"
     CDS             38208..39317
                     /locus_tag="AYP37_RS28340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="WP_000974903.1"
                     /translation="MAIKDIFEKLNSIEIDFSGISHWLAKYTFRYSRISLYEDLSGMLN
                     DGINVKRALTHLIDVETDYGKKTGSSATYYICCECLNALNNTGAISSALKKYIKEDEYQ
                     LISSGEIRGDLAGGLVQAIKIVRSRSEMTMTLVMSMIYPSVLVFGCLANMYMVHDTITP
                     VFLSLAPKERWTSSMRLLTDTSGFLIENGTYILCFCIVLFFLIRYSLARYTGPGRQYLD
                     YIPPWSLYKTFNGVSFLFNMASMLSIDIPVAKALERLEKNSTQNRWLLERIKEIRRYVL
                     LGQSLAMAMKSCGYDFPSKLCINKLLLHSENADNALMMSNYADKWLEEAKGKVKSTGVW
                     ITVVSALIVFAFIVMMITALYDVSNVLQH"
                     /name="type II secretion system F family protein"
     gene            39362..39919
                     /locus_tag="AYP37_RS28345"
     CDS             39362..39919
                     /locus_tag="AYP37_RS28345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4 pilus major pilin"
                     /protein_id="WP_000095049.1"
                     /translation="MSSINILNMRSVFSSLSARRKKEQDKGATLMEVLLVVGVIVVLAA
                     SAYKLYSMVQSNIQSSNEQNNVLTVIANMKSLKFQGRYTDSNYIKTLYAQGLLPSDMIA
                     DTTGASAKNPWGGSVTITTSSDKYSFNVVEASVPKKNCMAMVNALRSSSAISKINNTST
                     STVDAATVCSSDSNTLTFSTDS"
                     /name="type 4 pilus major pilin"
     gene            39986..40468
                     /locus_tag="AYP37_RS28350"
     CDS             39986..40468
                     /locus_tag="AYP37_RS28350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_023226007.1"
                     /translation="MRSVLYILLSCISSLIFSLQPAYSATTTQFDACFAQAGQRYLIDP
                     LLLKSIATVESSLIPDRINHNKEKGKILSTDYGLMQINSSHIPNLKKLGVIKDKSELID
                     NPCLNIQIGAWILATHFQKCGINWSCLGSYNAGFKESNEQKRIKYARYVYNKYMVR"
                     /name="lytic transglycosylase domain-containing protein"
     gene            40472..41107
                     /locus_tag="AYP37_RS28355"
     CDS             40472..41107
                     /locus_tag="AYP37_RS28355"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934977.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="WP_000934978.1"
                     /translation="MLNSIFNTAILCCANIVCQCYAYNEVKFRLNKLNVSYKTGTEKYY
                     CLILTTLAVLYLSLNQLSLIQSIIVIVFYAFLTLMACIDLLSFLLPRLYTVTFIFSGLL
                     YQTWNNNILSGLFCAMLMFFIMLFVRLYFAYKNGTESFGMGDVLLIAGTGVWFPTPEIA
                     CSIVFIAVIGGIIFFTLGGLNKQKKYIPFGPFLCGGMFVYSLVPGILF"
                     /name="A24 family peptidase"
     gene            41120..>42137
                     /gene="pilV"
                     /locus_tag="AYP37_RS28360"
     CDS             41120..>42137
                     /gene="pilV"
                     /locus_tag="AYP37_RS28360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /protein_id="WP_099356641.1"
                     /translation="MKKTDKGVSLLEVLLVIGIMVMVIPKVYENIENHLNNVRWQNAAE
                     HANTYNTAVRNYVADNASTLLAGSLPKTITPATLIQKGYLKSGFSESNFGQSYITGIAK
                     NSKTSRLEALTCSNGGQSLSEAGMRSVASMIEGLGGYINSSKQAIGAGGGWSDTPSNYG
                     LNCATGHIAMALVGADLQESDRLYRYSITNRPDLNRMHTAIDMNSNNLNNVGTLNGNAA
                     ALSGDISARNGTFSGAISGNTATTNGDITSNNGWLVTKNSKGWMNSTYGGGWYMSDSSW
                     LRSVNNKGIYTGGQVKGGTVRADGRLYTGEYLQLEKTATAGASCSPNGLVGRDSTGAI"
                     /name="pilV"
     Typing          complement(12442..13457)
                     /name="IncI2"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="97.837"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          18379..19370
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.29e-179"
     Typing          24921..27274
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="97.707"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          27444..28174
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.77"
                     /coverage="100.0"
                     /evalue="1.63e-146"
     Typing          28175..28941
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.609"
                     /coverage="100.0"
                     /evalue="2.9e-172"
     Typing          31164..33118
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.693"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gaggctataa acgaaacaaa atcgaaatca aaacaagctg tcttcaatat gtatttgcaa
       61 aatatacttg aagcaaagaa atattataca tgggagcaaa tagctgatta cataaacaac
      121 aacaccaaga cagaactagc ccaaaagact tatataaaca tgacagagag ggctaaaaaa
      181 agacaaaaat gctctgaacc aaaagaacag gcaaaaacca tagatgtaat tgatcagaat
      241 gaagctaaag acgatgaacc gagagggggg gtaaaaggtt ttttttcaaa cattagtgag
      301 agcaaaaaag aaatagagca cgatccaagt gctacgaatg aaaaattcat aaacaaatat
      361 ctttaagtaa aggagcatta taaatgaaaa actcaatcaa tttcatcctt cagggtaaag
      421 gtggtgttgg aaaatcattt gtgaccgcaa tactggcaca atactttatt gatgaaaatc
      481 acatggataa tatcgtagtc ggtgacacag acccggttaa tacaactacg gtaaaagtaa
      541 aaagattaaa tgcagatttg atacaaatca ctgaaaacag caaagtaata caatccaaat
      601 tcgatccaat gttcgaatca atgctgacca atagtcagaa tacctttgtt attgacaatg
      661 gcgcatctac atttttaccg ttaattcagt atttcaatga taactgtgtt atggacatgt
      721 ttgaagatgt agaacaagac gtttatatcc atactgttat cgttggtgga caagctcttg
      781 cggatacctt gcagggattt gaagaactga aagaactggt taaaggaagt aaggtaaaac
      841 ttattgtctg gataaatgaa tttcagggta ttccagcact tgaaaatatc ccattaatag
      901 aaactaaatt cattgaaaaa aacaaggatg taatcgctgg cgttgtggtt attcaggaca
      961 gaaaaagtga tgcctttgcc tctgacatca aagaactaac agaaaaatca ctaacactga
     1021 aagaagctct tgaatccgac cattttggat taatggctaa gtcaagatta aaacgagtct
     1081 tcaatgacat ttacaaacaa ttagatagca tctatgacga tgaacacggt gaataatatg
     1141 agtacagtta atcagccaga attaaaacag cctgaaaagg ctgtttccag tgaagatatt
     1201 gataatttta ttgttgatgt attcaaggag acagggcata aaatatcaaa agatgatcca
     1261 gttatttcat taatttttct gaaccaaaag atacaggaaa aattcagcaa tgagttacaa
     1321 gctaacttca cagccctgtc tgagggcttc agacaggttg tttcatctgt agaaaatgac
     1381 tatattcaaa gattcaagaa tatcgttgag acgtgcggcg atctggataa tgaaataaaa
     1441 gaaaaagtag aagagggaaa aaacgatcta aaagaaacaa gtgttgaggt aaaagaaaaa
     1501 ttaacagatg atattattga actcatatct ggaattaaac gcaaccagga aaaaaacaac
     1561 aaattatatg aagaaaagtt gaagtcatta tctaaggctg taaagccctt cagtacaaga
     1621 acagccattg caatttgtgc cttgtgcaca ttatgcctgt ctgcggcatt ttctggcgca
     1681 acctggtatg ttgcacaaca tgaaaaagag gcaagcctgc gcttctatgc aagagctttt
     1741 cttgatatga aaaaaataac tgaagagagc atgaggaaat taccaaaatc agaccagcaa
     1801 aatataaaac tcaaactaga agaaattgat tcaagaaagc cataaatatg aaaaggagtc
     1861 cctaatgacc acttttaccg acgaggacaa agaactaatt aaagaaatca gagagcgaat
     1921 tggcagcttg gacgtgcgag acaatattga gcgccgggct tatgaaattg ctctggcatc
     1981 gctggaagcc ggggttgttg catggaggta tcgttacgtg aaaaaagacg ttacggactc
     2041 tcagggtaaa acgtgggttg gtgactggaa atacgtaccg acaaaagaag actgcaacga
     2101 caggccgaac tatgaaattc aggaactcta caacttacca cctgcaatag cagcaccaac
     2161 agtaccaaga ggactagtaa acgcagtgcg tttctatgaa ctggtaaaga gtgagaatcc
     2221 gccagccgaa accggagcat ggaaagacgc tgttgactgg gtgctcaaag aggcttgcca
     2281 ggctgtaaac attggcatca aaggagagtg agaatgcaaa tttcaccggt tactcttcgt
     2341 gttgcgaagg cgtttatatc cagacatcac cgacacaata aaccacctgt tgggcataaa
     2401 ttcagcattg gtctgataaa tgatgccgga gaattgatag gtgtggcgac agctggtaga
     2461 cctgttgcac gacatttgga cgatggatta acacttgaag taaatcgcac atgtaccaca
     2521 ggagaacgca acgctaacag cgcgctttat ggtgctgtct ggcgggcagc aaaagctatg
     2581 ggttatcaac gttgtattac gtacacccag gcagatgaat caggagcatc tcttcgcgca
     2641 gctggttttg ttcgtgtgaa agagcttcct ccaagaaaaa gctgggcgga atcaagcgtc
     2701 gccctgcgga gtaaacgcga tccggtcgga aacggtggtg ttcctcgtgt gctttgggaa
     2761 atcaggagaa tgagtaccac tggcattcgc atcaaaggag agtgatatgg caactttaac
     2821 aaaaaaagaa cgggcatggt tgaacgaatt acaggacgtt cttgatcgct gcccatcacc
     2881 gaaaaaaatt ggtttttaca ccattggcga taaaagcatt tacctgtatg acctgcgccg
     2941 catggatgaa atcatggagg ctcttgataa tcgttcgtcg atggattggt gtgttgctgt
     3001 ccatgatatg aatgccggat ttgatgaaaa gattttattc ccctcatcag ttgaaagcac
     3061 agcaggataa ggactaacac atgacaacgt tcaccgacaa agaactgatt aaagaaatca
     3121 aagagcgtat aggcagcctg gacgtccgag acaatattga gcgtcgggct tatgaaattg
     3181 ctctggcatc actggaagca gaagcgccaa atttgcctgg tggtttcaca attgaagaag
     3241 caaaagaatt acacgaaaat ctggtaaaaa gtcacgtaag caaggcatta agtggcgaaa
     3301 aaatgaaaaa agaaaatcgt gatgccgatt tacgctggat tcatggcgta atagttcagg
     3361 ctgcgtggtt tgtgaaagca tcactagggc agaacgcata gtgcgtacct gcttttctcc
     3421 tggcaacggt ggatcttccg cttcctcgtc gctcgctcgc tatgctcggt cgctggactg
     3481 cggcgagcgg ttagctatca aaaaaaatcc ccgcacaacg cggggatagt tttatttata
     3541 tgcaagttca tgacgtgccg cctgagccag aaaatggcta cgatctttgt atacgccacc
     3601 actttctctc acatatccat caatacgacg aatcaataca tcaggcaatg aaatattaat
     3661 acgttgttgt ttgccctcaa tttctgacaa atcaacatca attacaaacc agctatcaca
     3721 gtggttataa tttgggttgg cggaataagt caaacaccct tcatcatgaa tatcatcaac
     3781 agaatgagca ccgcttatta ccatctcttc cacgattgcc aatatcgctt cacgcgccat
     3841 tgcgggtatt tctgcctgag aatcagcagc agaaacacat ccaaaatcaa agcaatcaaa
     3901 aaccggaacg gtgataccgt atgctgtatg atcatctttc ggtgtttcga caccaacaga
     3961 aaagaacatg gctacctcca aagtcggcgg ggattaaatc cccgccattt ttttgatcga
     4021 tctgacagta cctagcggca agtccttttt aggatgagga acaggaaaag tttttcctgt
     4081 tattggcgac caccatatct ggtgactgct tgccttatgc cgtttcaact cgcaaccagc
     4141 agctatcagt tctttcaaca ggtcagcaga tttcatatgt cctccctaac ctgaggataa
     4201 ttatacacac gcatacacac aaaggcaaat tatttcattc gtatgactta tgaaccacac
     4261 tgtaaagaca gctcaatctt tacagtgtaa gtcatttatc cagttttatc gctgtgtatg
     4321 tgatacatag aaaataatat agtattttac tatatgatat ctgattgaca cttttaactg
     4381 cacatctcat catttacatc gtaaagacaa acatagattt acaatgtaaa gctatgtaat
     4441 taaacactcc gtgtcccaaa taaggaaaga aaatgactca actaatccca gaaaagatac
     4501 tggaaatcat agatgatcat gatcgtgcag aaaaaaagca acgcaacaaa atcggtttca
     4561 tttatttatg tctctgttta gcaataattg gtgtggccgc gtataccttt atatcaacgt
     4621 ttagcattaa tgtggtaaca atcatcataa tgcttttcgg tgtgtttatg attgtgattt
     4681 ttaagagcta tttagactca tggagtggga taattcttag cagtgaccac atattgtcca
     4741 tactcgataa aaccaaagat tacccagaaa ttaaacgtat agttattaat cgtctgctct
     4801 ccggctcaat actcacgggt aaagatgaag agtacatata cagccaactg gaaaaggccc
     4861 aacaaagcaa cgaacgtgaa aagagattgc aagcaattaa agagtataca tcgtaataca
     4921 acgcattacg tcgaaatacc ctggatcatc gaagccacat acccctaagc gcagcgcaac
     4981 cgccggaaaa cgcaccacac tgtaaagaca ataaaatctt tacaacgtaa agctaactat
     5041 gtaatacaac gcgctacaca ataagaaagg gagagcatga cactctcccc atatatgact
     5101 caaactaaag cattatcccg gttatgcgcc caccaaatga tttcgctaat aatccatgct
     5161 tctatcgcgg gtgtttttac aggttcccca tttacaatgc ggtttgcaag ctctatcatt
     5221 tcacatactg acatttgaga atctccaaag atgcatctgt catttggtaa caggctgccc
     5281 cacagcctgt taccaacccc aaattaatat ttgctgatta ctttaccctc cttaatcatt
     5341 tttattagtt cctgttcaga atattctttt ccgtgttcca atgtggaata tatattgcca
     5401 atagtccata ccccacactt tttaatttct gcatttagcc aggattcatg cagaataaac
     5461 aacggttcgc aatcatttcc tttttcataa acataaatag attcggtatc atttccagaa
     5521 tcagaagtac caacgacttt ttctatatcg aaatgttttt ttagaaaagt tgtgaaatgc
     5581 attttcatgc tcctgccgct gagcggcttt ggtggttggg gaccatcccc tcccgatgtg
     5641 tttataatag gtcagaactg acctattatc aagtattttt ccctccattc ttcaaaaaaa
     5701 acaccatcaa atacagacag ttatattcat gtaatgcccg acagggcatg gaaggggcga
     5761 aagaaaatac cagggagcag cggggccaca tcgccccgaa gcgcggcgca gccgctgacg
     5821 aacataccag gatgcacagg gccatccctt cgccctgcaa agccagaaca gaccaacagg
     5881 ccatgatcat gctgatttgc gccgcagaat gccgcagtta gcgcgagcga cagcgagttt
     5941 acgccgtcct ggtgcattgc agcagggcgg ggcgctgtac tgcgcgtgtg agcgtcagcg
     6001 agctacgggc gcaattgctc attgttcaat gcaactgggg ctattaagtc cagccataaa
     6061 ttcagttatg gtttttgtag cttattccgt gatttcgtca tacgttaatt ctattttcat
     6121 cttaatattc cttaattact tccagaatca gaattctttt tattcctttt acaaagtaca
     6181 taatcagggt gttctccagc taaaagcaga agaaatttaa actctactgg tgtaagtgct
     6241 gtaccgcttg cagttccgac aggttcttct ttgcgacgcc aggtacgcgg actcatgctg
     6301 aatatttcag cacattcttt ctgtgtcagg ccaatttttt gccgcagacg tttaatgttt
     6361 tctggtgtgt tttcatttgg cattttttcc ctcactcatt tcctgaatca tcatagaaac
     6421 aatttcttta tcattctctc ttaatccgtc gctggcaaag tcgatagtgt cgaatgcctc
     6481 ctcatgaaaa acaagatcag caacagtttt caccgttgct ttcgtttttc ctaaagtcgc
     6541 agacttagaa aaagttttta ctcgcttcac cagatgaaac gtatcacctt ctttattcag
     6601 ataatattgt ctgtcacctt ttcttatctt catatcaaga tagtctcccc ttttaacagt
     6661 aaaggggcat atagcccctt tcttttaact ttttccggta atcaaatcga catcttcctg
     6721 ataaagttcc ccaagaaccg gaacaacgcc ctttttataa tcacggatat tatggcagtc
     6781 tgtaaaaatg acgacataag cctcgcctgt tttttcatgt ttaaggcaaa tggtgcaaag
     6841 cgtcacgcgc acaacagaaa acacatgacc agttgtagag acgataacag gaaaagtaga
     6901 ttgtttcata tttaatctcc tgccgctgag cggctttggc gattggggac catcccctct
     6961 caatgcatta ataataggtc ataaatgacc tattatcaag aattttctaa acgagcttta
     7021 ttgaaaaatc attttcaata aattcatcta acatctttaa tataccagct ttatttacga
     7081 aatcatcctc cataatttcg atacttgctg atatttcaca tgtaaactga atgctcctgt
     7141 caaatcccgc aatcccagct aatgcagaca gcatatgata attatcaata tttatattac
     7201 caataagaac tttcatttat cctcctgata tggggggaat cccctcatat taaaaattac
     7261 aatctggttg caagtccggt ttgttcatta aacaaacatt caagctgatc acaataaata
     7321 ttatcaaatt ttgatatttc ttttactgta gctccacgga cacgggaaaa tgtcaccagg
     7381 tatgtatcag agaaggttaa tttgatttta accaaattaa ttcccttcat tgcaaaattt
     7441 gaaggcaaac gaaagcaaag accacactca ccattttcat caaaacaggc aaagttcttt
     7501 gcgcctgtca tagcaatgaa gcgatttccg ccaagctgat taagaatttc agtagcaaca
     7561 aatttagcgt agttttccat ttttaaactc ctgccgctga gcggctttgg tgattgggga
     7621 ccatcccctc tcgatgtgtt tataataggt cagaactgac ctattatcaa gtattttttc
     7681 ctcctttctt taaaataaat atctttaaat acaaataatt acattcatgc aatgcccggc
     7741 agggcataga aggggcgaaa gaaaatacca gggagcagcg gggccacatc gccccgaagc
     7801 gcggcgcagc cgctgacgaa cataccagga tgcacagggc catcccttcg ccctgcaaag
     7861 cccaacagac caacaggcca tgatcatgct gatttgcgcc gcagaatgcc gcagttagcg
     7921 cgagcgccag cgagtttacg ccgtcctggt gcattgcagc agggcggggc gctgtactgc
     7981 gcgtgtgagc gtcagcgagc tacgggcgca acattacatt gctgcattcg cctggcattc
     8041 tccacgcctt gaaggacgga gttttactgc gcaccagata aaaaaagggg cgattaagcc
     8101 cctgtattca ctattaacaa tttaacatgg ttgcagggga taccccctgc aactattttc
     8161 ttagtagtat gatgtgaact cgtgtttttc ttccggtgat cctttatatg ctgtttcgaa
     8221 tgactcaatt tcaattgctg gcgtactgta ataatcacgc actcgccgtt ttaatggctc
     8281 accacagaaa tcattgagta atggggtctt atatccgctc attgaatggg tccgatgaac
     8341 cgaagcgcga atctcctgaa cagttacggt ttttttgcca tgaacagaaa taacctgata
     8401 gaaattaacg ttcgtttgct catatcccca ggaagataca aacacatcgc caacagaaac
     8461 agtgccgtta ttaaaagtta atgttttcat ttttatctcc tgccgctgag cggctttggt
     8521 ggttggggac catcccctcc cgatgtgttt ataataggtc agaactgacc tattatcaag
     8581 tatttttccc tccattcttc aaaaaaaaca ccatcaaata catatagtta cattcatgtg
     8641 atgcccgaca gggcatggaa ggggcgaaag aaaataccag ggagcagcgg ggccacatcg
     8701 ccccgaagcg cggcgcagcc gctgacgaac ataccaggat gcacagggcc atcccttcac
     8761 cctgcaaagc ccaacggact gacaggccat gatcatgctg atttgcgccg cagaatgccg
     8821 cagttagcgc gagcgccagc gagtttacgc cgtcctggtg cattgcagca gggcggggcg
     8881 ctgtactgcg cgtgtgagcg tcagcgagct acgggcgcaa caacacacca ggcaaaatcg
     8941 catcctgaaa agttaccctg taacatacac acaatgtaaa gcgcaaaaaa caattacatt
     9001 gtaaagacac aaacatcttt acaacgtaac tataatgaat acaatgtaaa gacaaataaa
     9061 cctttacact gtatatccga ggtttctatg gggagagcat tacttgtcgc atcagataaa
     9121 ggcggtgttg gaaaaagcac cacagcaaca aacctggctt cttatctggt aaataattca
     9181 cgaacggtca tcattctgaa gaccgataaa aacaatgata ttcttagctg gaacgaaaaa
     9241 agaaagcaga atggcttatt accggttcct gtttatgaag agtatggcga tgtatcagaa
     9301 gtcattaagc gcctgaaaaa aatatgtgaa gtgctgatca ttgactgtcc agggcatgac
     9361 agcaaggaat ttcgcagtgc cttaactgta gctgacattc tgcttactct cgttaagccg
     9421 tcttcagatt tcgaagcaga aacgctgact catgtaacag aaaaagttcg cacagctcaa
     9481 cagatcaatc cagacctgca accctgggta cttttcacga gaattaacac gacaaaacca
     9541 cgccacagaa aagcagcgat tgatctcgac aagttactcc gggagaaccc ggtgtggata
     9601 cagccacttc gtacacgtat ttcagattta gatatttttg aagcggcctg taatgaaggc
     9661 gctggcgttc atgatgtacg tcgcgcatcc agcctttcta cagctaaagc acaaatagag
     9721 cttttggcgc aagagttagg catcaatccc taatggatgt aatacgatag ctttacatca
     9781 ttaactttac acagtaaagc taatgtaaca cacgaaaggt gatataatgg ctcttgactt
     9841 gaaaactccg gtaataccag gacaaaaaac agaacaaacc aatgcagaca cagcccgatt
     9901 catcaatgaa gctacccgca aaaaatcggg agcaactaaa gtgaccaatg tccggcttgg
     9961 ggacgtttac gaagatattc tggaacggga agcactgcga acaggccaga caaaaacagc
    10021 aataatgaaa gcggctcttg cagcttacga acacggcctg gacgaaaacg gaaaaaatca
    10081 ctggattcta cagtcagcca ggctgaaatg ataaagccct tcggggcttt atcccttacg
    10141 ttttaattgt ttcttctcgc tggctttctt acgggcatcg agaaccagtt gcgcataagt
    10201 tgcgtgtgct ttttttactg taccagcagg tttcccgtaa aggtcgtaac gtgttgcgcc
    10261 tggtacagta caattctgaa gatattgcca ccggaacgtc atcacctgaa ccgcacaatt
    10321 ccactcttca atcgtcagat ccacatccgg gttatccgcc aggtatttct caacatcctg
    10381 gagaatcccg cttttcaggg gcaagttctt tttttcgtct gtccatagtt caggaaaaac
    10441 agcacgaact ttattgaaac acttttcaaa atattctttc ggatattttg ggggaaaagt
    10501 gatttgtttt ttcaaatacc agggctgagg ctgcttttta tgtgttttct ctgctacagc
    10561 atctttcttc tgtactttct tgttttcatt aactgctgat ttttgtactt cctgcggctt
    10621 ttcattcacc acaggatttt ccggcatgac cagaacgcgg cgttttttga ccacaatcac
    10681 gggtgttttt tttggctgca tactcgcctc aataattgct gtcatattga ctaattatac
    10741 cattttcagc agttaatatc ctgaaaatac atggaaaaag ggggtatccg tacagaatac
    10801 cccctttgca aaggcgctta atgccagaac cacatcatcc ccaaaaaggc gggctttcgc
    10861 ccgcctccgg gttgctactt accgttggat tcgtaagcca gacttgccgt aacctccctg
    10921 tttccatctt tcagccggac ctcgcacaaa cgattccggg tcagatacgt gaatattaac
    10981 aatgtgcagc acacgattaa taaacaccag gtcagggcgt ttttcggctg tttcatggcc
    11041 ttcttctcct tgcgtaacgc gcggtaagag gctatcctga tgttgttgaa gcattgggat
    11101 cgcctcgtgg gttaatgaaa aattaactac ggggctttct tctttctgcc gcacaacaag
    11161 atacaaacca ccttttcgcc atgaggcaga aagcctcaag cgccaacagc attatatatt
    11221 gaccaggaat taaattccca gctttcggcg tggactatac agtgtgtgat tcaccacgat
    11281 gaatcctttg ttgatccact gtgtgacctg cgcaggttga actccggtca gcctggcgaa
    11341 cgatgcctga ttcccccgat agaacttgtt gatgtattca atcaaaggca ttttttaatt
    11401 ctccgaaaca acgcaaaatc atatagtagt ttactatatg atttttattc cgcaagtgat
    11461 taactcatcg gatttctttg tagttaacga aacgttaaat ttagtttgtg cctggaatgg
    11521 cacgcaagaa gcacactagc attatcattt tgatcaaaac gctatttccc ccgttattgg
    11581 ggggctttct ttttgatgcc gcgccagcgg catgtaaggc ggcactctgt tgttttatat
    11641 ggcacagagc taaaccgccg aagcccggcg taagccggta ctgattgata ggtttcacct
    11701 tacccatccc catcctgcta agccataccc gctttcagcc atgaaatagc ttttgtgcgc
    11761 ggtcggagtg gtcccgacaa gggtttaccc gcagtcgggg cgtatctccg cgttagcggg
    11821 ccgtcagggc cgcttacgag cgtgtatttg gtacttccag ccagaaggct gacagcgatg
    11881 aaatttctta gttacaacat ccattattga aagcgatgtt gttcccgccc ttcgggcggg
    11941 ggcggcggcg cttttcagtg atgggtcggg cgctgtggct gagtatttgc agcgtttttt
    12001 tgtaggaggg ttggaggggc tttgtttttc attgggcaga agttcatatg cccgccgcga
    12061 agcggtggga ggtacttata ttctgagcgg cgcggcgtta gcagctgcaa gcgaaggcat
    12121 ttttgtgatt atccacagtt gtttcaaaga taaatatttt ccctgcggcg aagcaacgca
    12181 ggggattaaa gaacaggggt taagaatata ttgcgggttt gatgttctat gtttgctgct
    12241 ttctgaagtt attcctttgc gggtttttgt ggataaccga aggcgttttt actccgatac
    12301 cctattgcgg ccatcaaaaa actgtcagag cgggacaaaa tgaaaaacgg tcgtcaaata
    12361 tgaggaattt catgaaatgc aggcaacacg aaaagccccg aaggggctga agagagtgcc
    12421 gattgtatca ggcagctaaa ctagtggggt ggcgaagctg tcagggccag ttcaagctga
    12481 cgtagatccc tggctaccag ttgctctaat ctttctttag tgcaccagta cgcttcgtcc
    12541 ggcggcatac gcttcagaat aaaccgtgca atttcgtttc gctgttcatc atgcggcagt
    12601 tttgccaggc gattagcacg tttacgcttt gctgcttttt ctcgtcggga cttgatggca
    12661 tcgagagaac gctgcgcgta ccagcgttta cgagccgagt gaacagagat ttcctcgccc
    12721 tcgcggataa ccccttcttt aatcagttgc cgacggattt cactttctgc aaggcgctta
    12781 cgttgctgtt cctgaagttt caccagatca actcccagca ttttccagcc agtttcggtg
    12841 atccagacgt atttcggcag tcgctggcgg gattcacggt cccatatcgt cttttctgac
    12901 gttcccaacg cgccaaagca aacctgctct gccagcagac gggaaaggcg cgatactgtg
    12961 actgcggttt caggaataac gtttccctta ctgtcttttg gacttatttc ttttgcaagg
    13021 cgagatactg acatgccgat agtgtgcaat ccacgatcac aaaaactcac aagtacaacc
    13081 catattgcgt caagcagccg ctctttctcc ggtcggaact tatatttgcg accgacactc
    13141 tgacgtttca gtacataaaa tggatgcaac gacatgtgca ttctgagtgt gtactgacca
    13201 gttaccgggt cttttttaac gagacgattg taagcgtggc ccaactgtcc gcccagcgcc
    13261 ttatagctgt cgggacggaa ccaggctgga ttctcacact ttggcttagt ggaatgttca
    13321 ccccggcgac gttttgttgt tccgcctttg ttttcctggg ggaccaggaa tgagctttca
    13381 atgcccgctt cgtagtcctg ccagaaacgg acctgctctt ccggtgatag ttcagaccag
    13441 tgacgtttgc taatcacagc aagctgcact tagcttgcac tgtaagagtt gatatttcct
    13501 tctcatggaa ttaaactcca tttcaggtaa caagcatacc tgaaataaaa cgttatcagc
    13561 tcaaggctcg gccttgaggg caacccccgc taatctacgc tgcctggaaa acacgagatt
    13621 acgggggttt tctttatctg aaatttacgt tcttgaacaa aatttcagca cctcgttttc
    13681 tgcatttaca aatcgcggaa aacttgcctg caaatttagc agcatgggcg caatcgatca
    13741 acgatgttca agcctggctc gtttcctttt tgattcagca cacatctgtg actgcttcaa
    13801 aatcgttttc agaacagcta ctgaagcccc ttctttactg acgttcccca tacaaaacct
    13861 tacaaaatca gaaattcaga attttgtata ttcaaaaaag tttttttgac tgcatacacc
    13921 cattcacacg atcgaataaa ccacacaaac agtattatct agatttttag atcgtacatc
    13981 atttaacaaa cagaatatta ttctgttttt tagatgttat ccagatcatt agatcgctct
    14041 tgtggcattg acaggtttta aatgtcgcac acacaatact atccagatga ttgtaaaaag
    14101 ctcgttcatc gcgttttttg tgctcattgc ctggaaaatg agcactcttt gacgcccgtt
    14161 agaacgcttg tcatctcatg ctctttaaca accccggaca gcggtcattg cctaaagccc
    14221 tggcataagg aggttattat tcgtgcattt caagcaccgc tggcatctgt cagcaacggg
    14281 ctacgtaaca gagtgacgtg ccgcgccatc tacacaggta acgactcttt atccgcaaat
    14341 atcattctgc atacttaaac ccccttattt ggtgaactcg cgttgagtta atctcactct
    14401 ctccctgagc aagtcgtaca ggctgcaacg cagaagtaca ccagatttgc cagtctccac
    14461 tccaggtaag ggggtttagc tatgcatgat gatgaacaat cagataaaga gcctgtagtg
    14521 agtggctgca acttttcata attagcttat gacgctgtat tccggggatg tttctatttc
    14581 agacaaacaa ccgggagaaa atatggcgcg taagttaaaa attaatcctg tcattcctga
    14641 atgtgtggca gatttgaaag gatatccact ctatatcatc gttgcttatt ggggattaag
    14701 aaataataaa acgctcacaa caacggatgt tagccgtaat ttccttatta cacagcaaca
    14761 atcttatgat gtgcttacct acatttacca ggaagcacag aagcagataa cagcaactaa
    14821 acgaacacta tttaacgagc acaaaagaag aattagtgcg ttcaggattc ttgatattga
    14881 caaaggcata ttgcgcaccc caaaaaaaga gattgcatat gccagctacg acaatatacc
    14941 aactgtcaca atgaaaagta cccgttgtga gatccaggat agttttacag aactgcgccg
    15001 ctggatgtgt tcaagaaaga caggtgatcg agtggaggta tttttgaatg tctaagtacc
    15061 aaataaacgc aaccatcaaa aaaccaggtg gtggccccgt gaaatggact cattacagcg
    15121 acttccctat gaccgctgaa gaatgcagaa aaaacttctc aaaagaaaaa gaagcaggaa
    15181 agtgtttttc tgttgatgtt catatttcag atttcatttg caaagagata cctccacaaa
    15241 atgcaggaaa tacatatggc tgattttggt tccactaaac aaaccgtaac atttgaagaa
    15301 tggcacgagc tattaatgga ttacgcagag ttacgcggtg ggaatgccgc cgatgcggaa
    15361 gcatggcgtg gtgattatga agcaggaaaa actccggtag aagcatattg tgatgaatgg
    15421 ggagaggatt aatcatgatt gacgctataa ttacgccaat agttacatct attccggtac
    15481 tcttattaat tttagtcgcg ctgatattcg ttaaatctgc cgtcaaaatc gtgccgcaag
    15541 gtaatgcctg gacagtggaa cgctttggta aatataccca tacgctttcc cccggtcttc
    15601 acttcctgat cccatttatg gaccgcatag gtcaacggat caacatgatg gaaaccgtcc
    15661 tggatgttcc taaacaggaa gttatttcga aagacaatgc aaacgtaact atcgatgctg
    15721 tttgttttat ccaggtcatt gatgcagcga aggcagctta tgaagtcgat aatcttgcat
    15781 cagctatttc aaatcttgtc atgaccaata tccgaactgt cgttggtgga atgaatctcg
    15841 acgatatgct ttctcaacgt gacagcatca attctaaact gttaactgtt gtcgattatg
    15901 caactgatcc gtggggaatt aaggtcacac gtattgaaat tcgggatgtt aaaccaccag
    15961 aagaactgac taaggcgatg aacgcgcaaa tgaaagcgga acgtactaag cgtgctcaga
    16021 ttctggaagc ggaaggtata cgccagtcac aaattctgaa ggcggaaggg gaaaaacagt
    16081 ctcaaatact gaaagcggaa ggggaacggc aatcagcgtt tcttcagtct gaagcacgcg
    16141 aacgtcaggc agaagcggaa gctcgcgcaa caaaactggt gtcggatgca atcgctgaag
    16201 gtgatgttca gtctgttaat tactttattg cgcagaaata cactgaagca ctccaggcaa
    16261 ttggcacagc atcaaacagt aaactggtga tgatgccgct tgattcaagt agcctggtga
    16321 gttcggttgc aggtatcagt gaactgctaa aaaacgtatc acaggatact tccaaagttg
    16381 atatgaaaca ggctcaacag tatttgtctt aaacagatac cggacggtga caatattgtt
    16441 ttaatcaccg tccttatctc atggagattt acgatgttct ggtttacgct gtttcttctt
    16501 tgtattgccc ttgaaattat aaccggaacg ggatggttac tcgtaatcag tcttggtgca
    16561 ttatcaagtg ccattgttga ctttttcctt cctatatcac aagaagcaaa tatatgcttc
    16621 tttgcgtcaa taagcatact gacgtcgata attaagttcg tctatgacaa aaaacataag
    16681 aaattagata cacccctggt gaacacaggg cattcacgtt ttaaaggaaa agaatttacg
    16741 ctcagtgacg atattgttaa cggcaagggg caattactta ttggtgatac attctggcca
    16801 gttgagacgt tacacaatga aaactaccct gcgggaacaa gagttattgt tacagacatg
    16861 caaggaataa cacttaaagt catgaccatc gaagacaaga atgaaaacaa ggaataaatc
    16921 atgcatcttt cgttgttaat tccgcttaca ggagcagcga tgaatgcact atgtattttt
    16981 attatcagac ttctggataa ggattttatt gaagcctaca aaaaaacgct aaaaaacatt
    17041 actgcattac atattttatt gatggtgtta agtgtcacag gaatagtatg aggaaaatta
    17101 aatgcgaaac gcaaatgaag gagtatctct ttcagagatt gtaactaaag ccacattacg
    17161 caaatttggt attagaggtg taaataaata cgagacatac acagtcataa taaaactgta
    17221 gcttttttta tccttgaatc agcagcagga agggccaaag atacatttgc tgtagctata
    17281 aaagtattaa gctacatgct cccctgtacg gcaattatca tggctgtcat atggataata
    17341 tttttcatcg gcgatagacg agaaaagtta aaacatgcag aactggacgt gattaagata
    17401 aaagctcgtc aaaaaatcta cgatcgcctg cgttacgttg aaaatgagca tatcgttttc
    17461 gactcggtta caggtcggga agttccggca gaacggactt gtatcaatga acttgttgaa
    17521 gctctcgcga tggaagcaac aacgtgagaa ggtgacagcc ccctgaagga tacgatgaaa
    17581 tgtacagaaa aaaacatcac ctaataaaaa tatttttatt aaaaatggcg tgcaatgttt
    17641 tttctttcct gctgggtgct ttcatacttt cagcaccgtt tgtcttatat acattaaccg
    17701 gttcagttct gaatgccgtt attcatttca ccttttcttt gcctttagcc accatattac
    17761 tggtttatgc ttattcaggc tttgaagaaa gcatttattt attcatggca tacaaatatg
    17821 actcaagcaa aagctaatct gagaaaactt cgccgtgcac gttatgtccc ccctcgaaca
    17881 gtaaagaaaa gcatagcgaa tacagaacgt gtcgtttcaa aagcaattac cggctgtggt
    17941 gtcttccgtg atataccaca agtaaaaatc aatctcatcg aaacaaggaa aattttacaa
    18001 atcgaactgg ctttatccat tgctaactta tctgaggcga atccaattga gatacgaaaa
    18061 aaaatcaaaa gcattgaccg acaattatct tcaacctcaa aaatcagaac tacattatga
    18121 aaaaaaacga cgatttaatc actttaccat ctcataacag ccacgctctc gattacatca
    18181 ttaaaaaagc gtttacacca cgtaaaacca aaacatcgac agcgacccac aacgtttata
    18241 gttacaataa agaagaatcc acattaaatt tccaaaaaat tggagaagca atttttttcg
    18301 gcacagacct ggtaattaag ctgaagccaa atattagtgc ctctggtgaa ctcttcatct
    18361 gccagaagga ctaagccatg aacattgttt cagaatttct tgagaaagta acaaccattg
    18421 ttgaatccac agcggcgacg aacgccgcta aggtcgcaca agcaatatct cctacattct
    18481 ttgcggctat agccttatac gttatttatc taatatatga aatcacgtat gcccaacgtg
    18541 acgtcctgat gagcgaggtg actaagaata tcggtgcatt cgccctggtt ggtgcattca
    18601 cttattcagc gccttattac agccagtttg ttattccttt cgtaatgcac gctggctccg
    18661 acctttctgc tgctgttact ggaggttcag gaactgcaac cagtgttgat aatttgtgga
    18721 atatgctttc agtaacgtta aatgatttta agaataatga gttagatact ctggagtggt
    18781 atagcttcac agatcaacta tacatatatc taatttgggg ggttggatat gttggcgggc
    18841 tgctgcttat ttattacacc actgtatttc taactctatc aacattcatg gttggcattc
    18901 tcttatccgc cggaatatta tttatctgtt tttctctatt tgcttcgaca agaaatatgt
    18961 ttagcgcatg ggtaggtagc tgtttaaatt atatattgct aaatcttttt tatagtatat
    19021 cgttcagctt cgtcatcagc tttgtagagc aaacagtccc atcaagcgga aatataactc
    19081 tcacaacagt agtttatttc tttatggtga ctgttatatc tatattcctt gttgagcaag
    19141 taggtactct ctgctcaact cttactggcg gggtaggtat aaatggcctt acatcagccg
    19201 ctaatggctt tggaggtaag gttgcatccg gttttatgcg agcatcagga ctccgatctt
    19261 tcactaatgg ttttgccagc aaaatgccaa atccattctt taatgcagga agtcgttctg
    19321 catcagcatt agttcaggga ttaaaccgtg gaagtaaact taaagcgggg tgattaacat
    19381 gaaagataaa gtattatcat ttctctttgc tggaataatt accataacat caccatcaat
    19441 ctttgcatct ggtattccag tagtagacgt tgcagcaata gctaaaacag ttgaagaagg
    19501 gctaaatcgt gctgctgaag cggcaagaca gcttgagcaa ctcaagcaac aatatgaaca
    19561 gaccataaga tacgctgaag aacagaagaa aagactcgaa ggcttcactg atttcagcaa
    19621 tggctttgat agcgcatcca gctatatgaa ggattctcta tcaacaataa caaatagtgc
    19681 aaaatcagat cttagctctt tgcgatcgca atatgactta tcaagcaacg ttgcagagac
    19741 gcaacaaaaa tatgatgcga tcctggctaa gatcaaattc tatgaaaatt tcaacaatga
    19801 aatgcaggaa agggctaaga gattaaccac gttacagaag gagttcgcgt cagcagatac
    19861 tccgcaaaaa aaagctgact tatctaacca attgaataca gaaaaattga caatggagct
    19921 acaattgaag caatatgata ttgctgaacg gcaactagag aatgagcgga aagctcaata
    19981 tgaaacatat gttcgccaaa agagaagaga tttaagctga tatgaataag tcacgaaatg
    20041 caattatcgc ctcatcaatt atcttcgcca gtttaatgtt agtgggatgt aaagaaaaaa
    20101 tatattctgt agaatattac tcaaacaaca tcagtgaagc cactaaaact ttagaagatt
    20161 gcaagaaagg tacaataacc gatcaaaact gcgataatgc tcgtgctgca cttcagcaaa
    20221 aacaagatag tgaatataaa aagaaagtta gtgaaatgag aagacgcctt gattaaggaa
    20281 tacataaaat gctaacgaag cactctatga tctaaaacga aaagaaatca tgagttaaat
    20341 gcttggacgc tccaataaat aaacttatgc catgataaaa aacccgcctc gtgcgggttt
    20401 tcttttgcct gaaatatgga ggaactccat gaaatccatc attttatcga tggttgccgc
    20461 caccgcatta ctgtcaggct gcgcggatag caaaacacaa ccagtacctg agtcaccgtt
    20521 aacctcaaat gaccaccaga taacgttgaa aattgatacc gtgcgaacag acctgccgga
    20581 cagttctcct gtttgtttga atggtatgaa tatatacgaa agtctgagcg agcggcatcc
    20641 aggcttgttt gccaaaaatc agaacgtgat tttccgtagt gcattctttg atgacggtca
    20701 ggcgatatcc tccgaaacaa tccgcaaaat aatgcagagt accccgtgcg ttgaatcaca
    20761 aacaacatct gccggaagct gggaacctgc cacggaactg atcccccgtc aggcaatatc
    20821 cggtgacact acactggctg aaaaagatcg gactgctggc ttcacaatgc ggatagcacc
    20881 ggagattgag cgtggaaatt tccatctgct actcacaacc actgacccga tacggaaaca
    20941 gactgtcgag cagaatattt tactcaaacc ggaccagccc cttatcgtga gtggttttac
    21001 tggagttaat gctgatagcc aaagtgagaa ccggattgtc atcattacgc cacacgtgcg
    21061 ttgattcccc tgatatttaa attacccgcc tcgtgcgggt tttcttttgt ctgaaatatg
    21121 gaggaacacc atgaaatcca tcattttatc gatggttgcc gcaagtgcta tcgcactctc
    21181 tgcccccgta tatgcgtctg atccgtgtgc ttccgttctt tgtctgtacg gtaaagctat
    21241 cggtagcggc ggcgggagcg aatgcaaaag cgccgaaaag gacttcttta atatcataaa
    21301 aaagaaaaag ggatctattc gctggagcaa aacctttgat gcccgaaaag cgtttcttaa
    21361 tcaatgcacg accgcagacc ctgcggcgat ctcaaaaatc atgagtaagt tcggacgttc
    21421 ctggggttaa ccatgaaaaa gctcattatt attcccacca cattattgct gaatgcgtgt
    21481 tcccatgccc ctgaacccgc acaggcaaaa ggaggttggt atgaactgaa taccacaatt
    21541 gagcaggtaa gagcagacac atactataac ggggtgatcc ttcagcagcc cgtgtcacag
    21601 ccaaacagca ctgttcaata cagcaatgat aattatctca aaaaggaagc cataaacgta
    21661 actcccgcgc ctcgtattgc agaaaccgta aaaccacgtt ctgagcaatc agcgacagcg
    21721 ccaaaaaacc agggcagcaa taatagtttt ctgaagccga caacaaacag cataacttca
    21781 tctggtgaga taaaaacagc agccaaagga gcaactgaac agcattctga acaaccagca
    21841 ctccctcccg caaagccaat cagtagcaac aaccatcagg cacaaacggc acaaaatact
    21901 gatcagcaga caaaaccgcg tcctgaacaa ccaccgctaa tgtcaaaaag cggttttctg
    21961 aaaaaaaacg ctaacaacgc tgttccggcc accacgctta caggcccatc aacacctgaa
    22021 aagcaaattt actttgttcg ccatgatggt aaaggctcgc tgcaaaaagc agtaaaagaa
    22081 attgtcccat cggactggac ggctgaaata tccccggagg taacgaaaac tttccgtcgc
    22141 acgatatcct ggcagggcaa cgatcaatgg ccttatgtcc tggataaaat gcttcgcaac
    22201 tacggtctga cggtaattaa gaacaccgaa aaaagacatc ttctgattga ttttcaacaa
    22261 cagaaaggga aaacatcaca aaaagcacct gtatctcctg acaaaacccc tgcatctcct
    22321 gtcaggacac cagtttcctc tgacaagtta cctcaaaaac cgctaacgcc tgtcaccgtt
    22381 ccgcaaaaac agacagaaaa actcacctgg aatcttaaaa aaggttcgac gctgcgggat
    22441 ggcctcacag aatgggcgtc aagttcgccg tgtggtaatt caacctggaa tcttgtatgg
    22501 gatactcctg tgaactaccg aatagatgct cctcttattt tccggggaaa ctttgaatct
    22561 gcattaaaag atacgctgat gctttatctt tcagcagata aaccgttata cgcattcagg
    22621 aatattgcac aatgcgtaat cacaattaaa gacacacaac aggagtaatc gctatgggtt
    22681 ggttcttcag cttgctcctg atattcctgt caataggcag ttactatctg acagataaca
    22741 ataaccaaac catacagcga atgaagttgc ttcctgcaaa acaggaagca attgaatttg
    22801 tccatttcgc aaatgttatc aatgactatc tttataaata tccagacaaa cgtaattcag
    22861 gaggaacgtt aacatctgag caaatcggta taacacccgt ttatgatatt catcatatta
    22921 tttacggtaa gcgagtttat atctggtctg ccgatacaga aggtctgatg tctgctttgc
    22981 agcagcaaac aaaacattca gcaatgttag gaagagtaaa aaataagaag attgtcgata
    23041 atcaggggaa tgatatgggc gttcccgttc cttcctcaat tccagaagag gctattgtac
    23101 tcattaacta aatatcccct gacaagggga ttctgaactg gagtctgcat atccgacaca
    23161 tcattatgtg ggccggatat atcgctacgg cgcggacttc agtccagaaa atctttaccg
    23221 gagataccca tgcaggataa tgatgatgtc agcgagcttg atattgccac tcgtgaagtc
    23281 cttatcttac gatgcaatct tattcagctt gcttctgaat atataaaaat aaatcccctt
    23341 aaaaacacca gaatctacac agatttaatt catcgttcag cagatgttat caaaaatatc
    23401 gaacaaggta acatccagaa taaacataat tatctgtcac aggatgtaaa acatacgctt
    23461 gttttatacg acctgtacaa atcagacttt gaacaatgtc cgggggcaaa atcccttata
    23521 cctgtcaggg aaaaaattgt ctcgctgaaa gaacttcttt ccggcgctaa tgagctggac
    23581 agtatcgttc gtcgcccccg caggaaaaaa cgttcttcac gaatttaata tcaggagata
    23641 aatcccttat gcagttatca gcggctgttc tggcagcact gataagtcag tgtgcccctg
    23701 atgtatcacc cgatacgatg aatgccctga ttatgactga atcaggggct aatccatatg
    23761 taatagcgaa tgtttctgac ggaacaagta agtattttaa agatgaaaaa ggagctattg
    23821 aatatgcaga aaaattaaca gcagaaaata aaaggtttag tgcaggtctg acacagatat
    23881 acagcaaaaa tttcccatca ctcaatctga ctaataaaac agtttttgac ccgtgtacaa
    23941 atataaaagc aggagcggca gtcctgacgg acaattatct gagacaaaag gagggtagta
    24001 gtaatcaaaa aattctccgc gctttatctt tgtattattc gggtaacgaa tcaacaggat
    24061 ttattaaaga aaagaaattt aacaacactt cttatctgga acgggttatt cgtaacgcga
    24121 ataactatat cgtgccatca atccgtgaaa aaaccgatga atcagaaata aaacccccga
    24181 atgatgaaga gaaaacatca ccggactggg atgtttttgg agattttagt taatgaaagt
    24241 caaatcaact ttgcagtatt ttatcctggc gtttttcctg tcactaaccg cctccgttgc
    24301 ctatgcaggt ggactcgaca ccgcaacaaa taccatgaca gaacttaaga catgggcatt
    24361 tggctttggt ggtgtttgtg ctttgtgtta cctgatctat aacatcatca tggcattcat
    24421 ggagaagaaa agctggtctg atgttggaat ggcgcttatc tattgttccc tcgctggcgg
    24481 tgcactttac gccgggaact gggcgctgga actcttcaaa taagtaatcc atatatacaa
    24541 ctgtgccgca aatttacctt atgtgtgaat tgcggctttt ttcatggtga gttatggaca
    24601 aagtaaatga acatgtcagt gagtcattca tgacttataa cgggtttaac cgtcctgcgt
    24661 tagttgctgg tataccctta atgttgttat tgttcacggc ttttttcgct gttctgacag
    24721 gcttccccgc tatttttctt tggggtataa aagggataat tattcctgtc atatgtgcgc
    24781 tgtttctttt tatagtaaaa ctggcctgtg aaaatgactc aaacgcacta agagtcatcc
    24841 gtttaaacct tatggggctt ttgttaaaaa tccgccacag agatttaatt attggttatt
    24901 catctgtcag gtaacatata tgcacaaaat caaattaaaa aacagtgaca atatggatgt
    24961 tgctcgtgaa tatcccgatt atcgcttcca tataacagac agtattatct ttacttctga
    25021 caggaaaatg ctggcttcac ttgttgtagc aggcattcca tttgagacag agaacgataa
    25081 tgttcttaca aatttattta acagcgttaa aaacttcctg attgggttag gaaaggaagg
    25141 cgacctgtat ttatggactc atcttatcaa aaaaagaata accattgatg gagaatggaa
    25201 ttttgacaat gcttttttaa gcaggttttc aaaaaaatac cttgctctgt tcacatccag
    25261 cgcattctac aaatcaacat ggtatttaac atttgggatt ccctacgatg atgttgatac
    25321 cggaatcgag cgcatgaatg aaatgacaca acaggcgcaa aaagcacttc agccatttaa
    25381 cgcttctgtt ttatcagttc acaatactta tattagtgag gtggcagact atttatcact
    25441 attgctaaat acagaacata acatgattcc tttatcatcc actcccttat catccagtat
    25501 ttgtgattct gaatggtatt ttggtgctga tgttcttgaa ctgcgtaaca acgaatcgga
    25561 tagtaaaaag tttgcaacga attatatttt gaaggatttc cctatagaaa cgacccccgg
    25621 acaatgggat tttcttctca agcaacccta tgaatttatt cttactcaat cgtttatttt
    25681 tgaatcaccc acaaaaaccc tgaagaacat tgattcgcaa ttaaacaaac tgcaatcagc
    25741 taatgatgca gccaaaacac aacaggaaga actcgaagct ggtaaagaag cggtcgcagc
    25801 cggaattacg ttgtttggtt cactacactg cgcattaacg gtattcggtg atacaccaga
    25861 tcaggccaga agcaatggta taaagctctc tgctgagttt attacttcgg gtaagggatt
    25921 ccgcttcagt cgcgcctcac tcgcatcacc ttttgttttt ttcagtcata tgccgctgaa
    25981 taagaggcgt ccactggata cccgaagaac aataaccaac ctggcctgtc tgatgtcttt
    26041 tcacaattat tcctccggga aaaaatcagg caatcctatt ggtgatgggt ccgccataat
    26101 gccgttgaaa acggtgtctg acagcattta ctggttcaat acgcattaca gcccaccgga
    26161 aaaaaatgtt accggacaaa aaattgccgg gcatggaatg attcttggcg caacaggcac
    26221 agggaaaaca acatttgaag cagcagccag cggttttctt caacgctttg accctttaat
    26281 gtttgttgtg gatttcaacc gttctactga gctttttgtc cgtgcatacg gaggaagcta
    26341 tttcacgttg caggaaggca tttataccgg ctgcaatccg tggcaactgg cagaaggccc
    26401 ggaatctccc gtctggcaca gacttctcgc atttctgaaa cgctggacac aggttctggc
    26461 acgagacaac cagggcaacc cctgttctga tgaacatggc attgaattaa acgctgccgt
    26521 ggaaagcatt atgcgaatgc ctgtcgaaga acgccggaca gcccttcttc tcgatatagt
    26581 cagtcctgaa cttcagacgc gtctcgccaa atggtgcgac aacggcgaat atgcctgggc
    26641 ggtggattcc ccccggaata ccttcaatcc actgcatcat aaaaaggtgg gatttgatac
    26701 aaccgttgtc ctggacacaa aaaacggtat tcatcctgcc tgtgaacctt tactcgcggt
    26761 cctgtttttc tacaaagaaa tcatgcaacg cggcggcaat ctgatgctct ccattattga
    26821 agagttctgg atgccagcaa actttcccat gacacaaagc atgattaaaa gcgcactgaa
    26881 agcggggcgc atgaaaggtg aaatgatgtg gttaacatca cagtccccgg aagacgccat
    26941 aaactgcgca atttttgcgg cgctggtaca acaaaccgca acgaaaattc tcctgcccaa
    27001 tcccgatgca aaatgggaag gatataaaga aattgggctt actgaaaaag agtttgaaaa
    27061 actcaaagag ctgacgaagg agtcaaggac catgctcatc aagcaatctg gctcttctgt
    27121 tttcgccaaa atggatttgt ttggattcga tgagtttatc cccgtgcttt ctggctctga
    27181 aactggcctg tctatttttg atgagattat tgctgaaaaa ggagatgtag ctcctgatat
    27241 ctggatacca gaactcctga aacgcctgaa cggttaattt ctctgtttta tacagaacgg
    27301 aaaacaatat gaaaatcccc ctcataattg cctccgcgct attaattagt gcatgttctc
    27361 acacccccaa tcctgtgcag aaaaaagggg gatggtttga gttaaacaca gcaattgaac
    27421 agatcaaagc aggtgattat taatggaaaa cacaaactat tatgaacatt caaaaaaaga
    27481 agccaccaaa aagaaatttg aagaaaaaaa cgaaaaaaag gattatttca aggccatacg
    27541 tgactttgag cgcagtgaaa ttgatatcat aaagaaaaag gcaaaaacat ttaccattct
    27601 cgccattggt gaatttgttg taatttgcat tcttggtttc gcaatagcct cccttgctcc
    27661 attaaaaacc gctgtaccgt tccttgtgcg agtggataac agcactggat atactgatat
    27721 tgcccctcaa ttatctgatg ctaaggaaag ttatcaggat gttgagacta aatattttct
    27781 gtcaaagtat ctcattaact atgaagcata cgactggcag actatccagg aacaggccga
    27841 tacagtaaaa acaatgtctt cccaaaaggt gttttcagct tatgacacca tgattcgtgc
    27901 tgattcctca ccactgaaca ttctgaaaaa caactacaaa attaaggtcc agattaattc
    27961 agtaatcctt ctaaggaagg atatggcgca ggtgcgtttc aaaaaaatgg tactggattt
    28021 atctggtaaa cccgcccccg gatacagagc aacagagtgg atttcgacga tttcttttga
    28081 ctgggataaa gatatcaaaa cagaaaaaga gcgccttgtg aatccgctgg gactgcaagt
    28141 tctgagctac caacctgatc cagaggttat aaaatgatgc ttaaacgcac tactgcgata
    28201 gttcttttgt cgatgctaca agtacctggt gctttagcag ctatgtacgg cacaccatcg
    28261 gaacgagacg ggcgtattca gaccgtagat tataacgagc aggatgtatt taatgtgcgc
    28321 gtaaaagcag gcgcacaaac aacaattaag ttcggacaag acgaaacaat aaaagatgtc
    28381 ggaattggtg atccagaagc ctggtcagta tcggtcaggg acaacactct gtttctgcgt
    28441 ccaaaagcag aagaaccgga tacaaacgtt accgttcaga ccaataagca tatatatcct
    28501 ctttacctga tatcaaccac gaaacaaccc acgtatattc tgcgttttaa ttatccgaaa
    28561 ccaccgtcag ctaccgtaat gactgaaaag ccatttccat gcactgatgg tggaataatt
    28621 aatggtcatt atcaactcaa gggtgacaaa tcaattttcc cttatcaggt atgggataat
    28681 ggcgaattta catgcatgag atggactaat aaacaggaaa ttccggtcct ttatcgtgtt
    28741 gatgccgatg gaaatgaaca tctggttaac ggagacagaa ataaaaacac aatggtttat
    28801 tatgacgtgg ctgaaaatct ccgtttgcgc ctgggtgatc aggttgcaga tatcagaaca
    28861 tcatcaatcg ttaatcgtcc gtggaataaa aaaggtacgt caaacggaaa aacacgagta
    28921 gagaagttca gctatgaaaa ataaagatga tgaaaaaaat aatgacgcgg gaaatcgcgg
    28981 aattatcgaa gtaaaaggta aagcagcacc aaaaaaaata ttaatcctca tcatattact
    29041 gattgccgcg ttatttgtga tcattatctt gtttaaagtt ctttcacgag aacaggtcgt
    29101 tcagcaaaca cctcttgaga agtctgacga gacactggtc acaaatacca acaatggcgt
    29161 ttcactgaca acaatgatga aaaacatcga agaaaaggaa aaactcgatg ccgctaaccg
    29221 caggaaagca caggaggagc aagaacagaa acaggcagac aatgccccgt cagcgccagc
    29281 atcacaaaag gccgatcaaa cagccgtcaa tgtgatagcc aacggcagtc cccaaaccgc
    29341 cagtggagat ccaaaccaac cacaaccatt gccaaaatcc gtccgacaac tgatgggcga
    29401 cacaatggtg aagatcgaca atcaggaacc aggcgaaaaa aaccaggaaa gagatgattt
    29461 acagggcagt cagtacgcag acggaaaggt atcccctgtg ctgaaccgcc gatatctgtt
    29521 atctgcggga acagcattat cctgtgtgct caaaacgaaa atcgtaacct cttatcccgg
    29581 tatcacaatg tgtcagttaa cacgagacgt ctggtcggat aacggcgaag tgcttcttgc
    29641 ccgtaaagga gcattactga tcggggagca gaataaagtc atgacacagg gagtagcccg
    29701 tgtgttcgtt aactggacaa cgctcaaaga tgaaaatgtc aatgtgcgca ttggcgcact
    29761 tggcactgac agtctgggcg cttccggcct tcctgcatgg gtcgataatc attttggtca
    29821 gcgttttggt ggtgcattgc tgctgtcatt acttggtgat ggtttagata ttctgaaaaa
    29881 cagcacgcaa caaacaggct caaacagcaa tatcacctac gaaaacacat ctgacgcaac
    29941 aaaagaaatg gcaaaaacaa cgctggacaa tactataaat attcccccca cggcatatat
    30001 taatcagggg actgtattgt ctgttattgt tccgcgaaat atcgactttt catccgtata
    30061 tgaacttcag taattcagta aagcaattga tatgaataac atcagagata ccagtaatac
    30121 atcacaacca cgagataaca gtaaaaccgc aagacgatat ctggatatga cgggtatcca
    30181 gtctgttctt aatattgaac atgtcacaga aatatctgtg aataaaccag gaacaatatg
    30241 gtttgaagga aaaaatggct gggaatctaa agatgcgcca gacgcgactt ttgataattt
    30301 aatgacactt gccaaaactc tgacgaactt atcaaagata aaaataccac ttagccatga
    30361 taatcccatt gcatcggtag ttcttcccgg tggggaacgt ggacaaatca tcattccacc
    30421 tgcaacagaa aataacagcg ttgtgatatc tatccgtaag ccatcattaa cgcgctttac
    30481 tatagatgat tatgtccgaa cagggcgttt tgataatgtc aggattgcga cgaaacacga
    30541 agccatcctg actgaacggc aacgctacct gtatgaatta tcccggcgtc cagatggtca
    30601 atctaaagct caatttttaa gagaggcagt taaagaccgt cttaattttt taatcgtcgg
    30661 tgggactggc tccggtaaga caactatagc aaaggcaatt gcagatatct ttccacctga
    30721 acggcgttat ataaccgttg aagatgtacc ggaaatgtct ctgccgctgc atccaaacca
    30781 tatccggctt ttctacaaaa aaaataccgt tgaagcgaag gaaatcattg aagcgtgtat
    30841 gcgattaaag ccagatcaca tctttcttgc tgaacttagg ggtaacgaag catggagtta
    30901 tctggaggcg cttaatacag ggcatgaagg ctcaatcagt accattcatg ctaataatac
    30961 ttatgcctca ttttcacgac tggcaagtat tgtaaaacaa tctgatgttg gtatgactgt
    31021 tgatatggac ctcatcatgc gcacgataaa aacatcaatt gatgtcattc tttttttcaa
    31081 ccataccaga atgactgaac tgtattacga acccgaagaa aaaaatcgct ttttgagcac
    31141 aatgtaaatt ctggagataa ctatggatgc aaaaaagacg gggggattaa ttctcttcct
    31201 gttactgctt cttgtgggtg tgcttatagc ctcaaactat ctcggtggat acacagcatt
    31261 aagatattca tccgttgata tgtctttgct caagtgggat acattccatt ctgtaatctc
    31321 aacattttct ggcaaccctc aatataaaaa actcgttttt atggcatggt ttggattcag
    31381 cgttccatta atattctttg ccatattcat gttaattgtc gtgattggga ttatgcctaa
    31441 aaaagtcatc tacggtgacg cccggctcgc aactgatatg gacctaagta aatcaggttt
    31501 tttcccggat aaaaaatcac cttacaaaca tccaccaata ctcatcggta aaatgttcaa
    31561 ggggagatac aaaaaacaat ttatttattt cgccggacaa caatttttaa ttctttatgc
    31621 cccgacacgt tctggtaaag gggtggggat tgttatcccc aactgcgtaa actatccagg
    31681 aagtatggtc atactggata tcaaacttga aaactggttt ttatcagccg gattcaggca
    31741 aaaagaatta gggcaaaaat gctttctctt tgcgcccgcc ggatacgcgg aaactatcga
    31801 ccaggcaatt aaaggacaga tacgctctca ccgctggaat cctctggatt gcgtcagtcg
    31861 cagtgattta cttcgtgaaa cggacctggc aaaaattgcc gcaatcctta tcccggcaag
    31921 tgatgatcct atatggtctg attctgcacg aaaccttttt gtcgggttag gactttacct
    31981 gctggacaag gagcgttttc acctggaaca gaaagccaaa ggtcataatg taccggacgt
    32041 tcttgtttcc atcagcgcca tactgaaaac gtcggttccc gatggcggca aggatctcgc
    32101 cgcatggatg ggacaggaaa ttgaaaaccg tagctggatt agcgataaaa caaaatcatt
    32161 cttctttaag tttatgtcag caccagatcg cacaagggga agtatagaaa caaacttttc
    32221 atcaccgctg agcatcttca gcaaccctat tactgctgag gcgacgaatt tcagtgattt
    32281 tgatatccgg gacattcgta aaaagcccat gtcaatttat cttggtctga caccggatgc
    32341 tttaatcact catgagaaaa ttgtaaacct tttcttctca ttactggtta atgaaaactg
    32401 tcgtgaactg ccggaacaca acccggacct gaaataccag tgtcttattc tcctggatga
    32461 atttacatca atgggtaaat cggaggtcat tgaacgcgct gttggtttta cagcaggtta
    32521 taaccttcgc tttatgttca ttcttcagaa tgaaggacaa gggcaaaaaa gcgatatgta
    32581 cggtcaggaa ggatggacca cattcactga aaacagtgct gttgtgcttt actatccgcc
    32641 gaaatcaaaa aatgctctgg ctaaaaagat ttcagaagag attggggtgc gtgatatgaa
    32701 aatatccaaa cgctcaatat ccagtggtgg tggtaaggga ggaagttcac gtacacggaa
    32761 tgatgatgta atagagcgcc cggttcttct tcctgaagaa attgtgtctc tccgggataa
    32821 gaagaataaa accagaaata ttgcaatccg tgaaattata accagtgaat ttagccgacc
    32881 atttattgcc aacaaaataa tctggtttga agaaccagag tttaaacgcc gcgtggatat
    32941 cgcccgtaac aatcatgttg acattccaaa cctgtttaca caagaagtca tggatgaaat
    33001 agcaaaaatt gcagaaattt atctccctaa agctggagga aaaaaagtca tggttgccgg
    33061 aggcaatgtg attactaatc cagaccttga taatcacgat aaaacagacg tatctgaata
    33121 atcctcgcaa ccagcaaata gtattttgca tattccataa ggtaattaaa catgaataaa
    33181 aaattgcttt gtttattaat atcctctttt ttattatcag gctgtgcaaa cttcaaaaaa
    33241 atcaatgcta atgaacttgc tgccgaaaga gacgcacaaa aagcgactga atacgcgaaa
    33301 aaaattcgta ataacccggt tatccaggat tcaacaaaac aatggattaa tacaacgcca
    33361 attattgaaa agcaggtaaa gcaatcagcg ccgccctgcc cgattgtgat taatactcgt
    33421 tcagatattg agctacgcca gatcgcacaa cgcatcacac aaacctgtca tatcccggta
    33481 cgaatcagcg ccgatgtctg gacctatctg aacggtacag gcactggctc aacacaacaa
    33541 atgacaggct caattccagc acctgatgca aatggaatgg ttcctctggc gtcagtaggc
    33601 agtcagccag taaaagtctc ttctggcggt acatcactcc ctgaactgaa tatctccggg
    33661 cttcctgccc tactgcaaac cgtatcttca cggctgggaa tatcctggaa atacgataaa
    33721 ggtcgtatca cattcttcta tctggaaacg cgctcattcc cgattacata tatggacagc
    33781 aatgtggcat acaactcaaa agttgtgagc ggcacaatgt cttccagtgg cagtaccggc
    33841 tctacaagtt ctggcggtat gactggcgac gcatcaaata cgcaaactac aaccgtggaa
    33901 atgaaatcat cgctgtacaa cgacctgaaa agcgaagttt cctcaatgct gacaccaggt
    33961 acagggcgca tgtatctgtc cacaggttca ctgacagtaa cagatacccc ggatgtactg
    34021 gacagcgttc aggagattgt gaacaagcgc aataatgaaa tgagtcgtca ggttgtgctg
    34081 aacgttgaaa tcctgagtat caagaaatca agccaggaac aggcgggaat cgactggaac
    34141 gcagtattta atgatggtca tcttggtctg agtcttggtg gctcatttgg tgatgccgcc
    34201 gagaatgtta ttaccagtgg tgtatccatc gtggacggta agctggctgg ctcaaaagca
    34261 tttctgaaag ccctgtcgtc acaaggcagc gtcagtgtcg taacgcaaaa ctccgctgtg
    34321 actaaaaacc tgacgcctgt ccctatgcaa attgccaatc agcagggctt cattgaaagt
    34381 gtcacaaccg attctaccgc caatgtggga tcatccacgt cactgaatgc ggcaacaata
    34441 acaaccggat tcaatatgac tctgcttcca tacattcagc cggattcaca aaacctgcaa
    34501 ttgctgttct caatgagtct gtctgacaaa cctacttttg aggtgttcga aagtggcggc
    34561 agtaaagcac aaacaccgaa tgtggatttg aaaacaatta atcagactat tgatctgaaa
    34621 tcaggccaga cagtcattct gagtggattc cagcaatcaa accggaaaac cagtaagcaa
    34681 ggtgtaataa ccccctcctt ctttggactt gggggtggcg ttaacagcga agacggcgac
    34741 acgattctgg tcgttttgat tacaccaaat gtgcttaatt ccggctccag tgcagtaata
    34801 aaaaatgtga actaattaac tgaaaactcc ctgaaaaaac acagggagtt tttttggagg
    34861 tcactttgtc tgagaataat cagaataacc agaatttcac ttcggttatt aaaaacaagc
    34921 gtgctttttt ctccggtctg gactggaaaa cgcttccttc agaagaaaag aatgcgcgta
    34981 cattcgcaag aaaaaacgac gctgaatatt ttctctcctg tcagtatcag gattcagaaa
    35041 atgaaaccaa aacgatggtg gcatttatca gaaaagagga tcttcccaca ggggcgtcct
    35101 cattctggtc actggcactg atgataaaac ccctcatcga acctgacgga tacgctatct
    35161 gcgaactcgg tgatctttat ggctttgttt cctgcgtcaa taacgttctc gtcaacgatg
    35221 ttgtaggtaa caaaagtcag atcatgagtg ctctgacaac atttcttgag tttaatgaaa
    35281 caccagaacc cggctggaaa ctataccagc ctgaatcatg ggatatcagc caggcactcc
    35341 cctcactcac tctgtctgcg ttgattgacg taaaaaaacc gccgaaagag gcggcgttta
    35401 ctcgcgtatc ccgaaaacgt cagttcatga tttatggcgg aagtgccatt ctggccatac
    35461 tgctctggaa cgggatcacc atgtaccagg aataccggga aaaagaagct gcggcagaag
    35521 ctgcacgtct tcgtctggca aaagaaatgg cagacaaaca ggcaatacag attgccccac
    35581 cgtggcaaca tttacctgaa ataaaaccat ttattgataa atgcattgat aaatgggatg
    35641 cactgccctt atcgatcgcc ggatggcgtt ttgaccttgc tgaatgcagc acatccggta
    35701 atgacgggct gttacgcaca tcatataagg aactgagcgg cgttacggtc gaggacttca
    35761 gcacacggat acgagaaata ttccagggga caaccacagc aacttttgta ttgccagaag
    35821 gcagcgccgg gggattttct cttcctgtca gttttgacgt ttcgcctgat ccaattaccc
    35881 cggacacatt gccacaggca acagatattc aggaacgcct gacaacattt gcacaaaaaa
    35941 tgaggttaaa actcacctgg caggaaattg aaaacacaaa aacagatgaa gaaggccgtc
    36001 caataattct cccgtggaac gagtatgaat taatgattca gaccagcacc ccgccttcaa
    36061 tacttttcgc taactttcat gaacctgccg ttcgcttcca gtatgcagga ataaaactgg
    36121 aagaaggaag actgaattat gagattaaag gtgcattcta tgttaaaaat aattaaacca
    36181 acgattattt ctgtctgttt tttcagttca cttgcttacg caacagaatc tgaaagcaca
    36241 ccaaaagacg aaataaaata ttcatctccg accattttac aggtagagca gattcaggct
    36301 gaaacggtaa tttacgaagc aaagctggcg cgtcagaagg ctgtcagtga attgcgtaat
    36361 cttgatttga atggtgtagc gtccgcaacg ccagcaataa cgccctcttc cgggtattct
    36421 tctcttgcag ataccgatat accagcgcaa cgtgtagccg ctaaatcact tcgtgttatt
    36481 gaaatatttg gtacaccaca acaaatgtca gcacgaattt ctctcctgga cgggtcagta
    36541 actgatgtca aggtcgggca aagtattcct ggtacttctt ataaggtggc atcaatcact
    36601 ggtaatggcg tctggattca gaatggtaca gagaaacgcc agcttattct ttaatgctat
    36661 tgaaagagac gacacataat gtttttttct gacgcagact atcccggaaa agatatttct
    36721 gatgttgtat acgtcagtat atctgaaaaa gacgataaac ctgttcaggt ttatatcgct
    36781 gataacagta aaggacagcg tgctgttcag gcttatattg gcactctgaa tgttaaatat
    36841 cccggacagg taaatataac ctcgacaact cttgatgtta tcgcatcccg ctaccaggac
    36901 agcgaaaaaa ggtctgattc aaactcatca caacacttaa acagcaacca ggaaaaggtc
    36961 attagctacc tggcgaaagc aaacaaactg ggaagttccg atttgcacat cacacctggt
    37021 cgggacggct ccgagttcac ttatgtcgaa gcacgcgtgc atggggaact ggaaattctg
    37081 gatgtcatcc cgcgtaaaga agggctggaa ttgctgggtg ctgcctattc tggaatgagt
    37141 gatgttatca aaggtacgca gtttgaccct gcaataccac aggatgcacg tatcgcagag
    37201 aattttctga agcctgtaaa tctttttggg gcgcgctatt cgcattatcc gtgcgtgggt
    37261 ggtgtgtacg cggtcttccg cctgattaaa gatgacagcg aggatattcc cactttcgaa
    37321 gaacttggct acatgccgca acaaatccag acaatcaggc gaatgttaca acgcccggaa
    37381 ggaattatcg ttttatccgg ccctacaggg tccggtaagt caacgactct gagaacggct
    37441 tcagaagcct atctgagcac gtttggtttc aaccataacg ataatatgcg tctcccccga
    37501 aaacgccttt tcaccattga atcaccgccg gagggccgca ttcccggcgc aatacagacg
    37561 gcagtcaggg attccgtcga tggctgggtt gacgcgatta aatccgctat gcgacttgat
    37621 ccagacgcga tactgaacgg cgaaattcgt gatcacgcat cggcattagc agcaatcaaa
    37681 gcctcgatga caggccacct tctgttgacg accttacacg ccaacgatgc cctgaatatt
    37741 attgagcgcc ttgaaatgga gaatattcag gccaggctga ttgcagatcc tcttctgttt
    37801 atcggtctgc tgagtcaacg gctggtacaa aaactctgtc cttactgtaa gcgcacttat
    37861 gctgaaatgg cagacaaact gagtacagaa gaacggaaac tcattgagga aaattgcctg
    37921 ccggaacagg tccggttgcg caatcttgac ggttgcgagc actgttataa aggcgtaacg
    37981 ggaaggacgg ttatagcaga agtcgtctca cccgacgcac gtttttttca gttatatcgt
    38041 cagtccgggc gtctggaagc aaaatcatac tggcactatg aacttggagg aattacccgt
    38101 aatcagcact tattacacct gattaatcat ggcctggtag atccgctgtc cgcacacttc
    38161 atatccccca ttgacgaaga taaatactca atgctcccgg aggggacatg gcgataaaag
    38221 atatatttga gaaactcaat tcgatagaaa ttgatttctc tggaatatcc cactggctgg
    38281 caaaatacac attcaggtat tccagaataa gtttatatga agatttatct ggaatgttaa
    38341 atgatggcat aaatgtaaag cgtgctctta cacacctgat tgatgtagaa acagactacg
    38401 ggaagaaaac ggggtcttct gcaacctact atatttgttg tgagtgcctt aatgcactga
    38461 ataacacagg ggctatatct tcagcattaa aaaaatatat aaaggaggat gaatatcaat
    38521 taatatccag cggtgaaatt cgcggcgacc ttgccggagg attagttcag gccataaaaa
    38581 ttgtcagaag tcgttctgaa atgacaatga ctcttgttat gtcgatgatt tatccatccg
    38641 tactggtttt tggttgtctg gcaaacatgt atatggtcca cgataccata acacctgttt
    38701 tcctttctct cgcaccgaaa gaacgctgga caagttctat gcgattactg acagatacgt
    38761 ctggtttcct gatagaaaac ggaacgtata ttctctgctt ctgcatcgta ctgtttttcc
    38821 tgatcagata ttcgcttgcg cgttatacag gaccgggccg tcagtatctt gattacattc
    38881 ccccctggtc actttataaa acatttaatg gtgtaagttt tctcttcaac atggcctcca
    38941 tgttaagtat tgatattccc gttgcaaaag cactggaaag gctggagaaa aacagcactc
    39001 aaaacagatg gctactcgaa cgaataaaag aaatcaggag atatgtttta cttggacagt
    39061 cacttgcaat ggcaatgaaa agttgcggtt atgacttccc atcgaaatta tgcattaaca
    39121 aactattact tcattctgaa aatgctgaca atgcattgat gatgtctaac tatgctgata
    39181 aatggctgga ggaagcaaaa ggaaaagtca aatcaacagg agtctggata actgtagtat
    39241 ccgcattaat tgttttcgca tttattgtaa tgatgattac tgctctctac gatgtcagta
    39301 acgtcctgca acactaatcc ctaatatttt taacctctca ataaataagg aattatttat
    39361 tatgtcttct attaatattt taaatatgcg ttctgttttt tcttctcttt ctgcacgccg
    39421 taaaaaagaa caggacaaag gggcaacact gatggaagtg ttattggttg ttggtgttat
    39481 tgttgtactt gcagcaagtg catataaact ctattcaatg gtgcaatcca acattcaatc
    39541 atccaatgaa caaaacaatg tcctgacagt gattgccaac atgaaatcac tgaaattcca
    39601 ggggcgttat actgacagta actatattaa gactctctac gcgcaaggat tactgccatc
    39661 cgatatgatc gcagatacaa ctggcgcaag cgcgaaaaac ccgtggggcg gctccgttac
    39721 aatcacaacc tcttcggata aatactcctt caatgttgtt gaggccagcg taccgaagaa
    39781 aaactgcatg gcaatggtaa acgccctgcg ttcttccagc gcaatctcca agattaacaa
    39841 cacttccaca tcaactgtcg atgcggcaac tgtttgctca tctgacagca atacgctgac
    39901 cttcagcact gattcctgat ttttcatgtg catcggataa gcgccttcgg gcgcttattt
    39961 tttccatgtt tacaggagga gtattgtgcg ttctgttctt tatatcctgc tatcatgtat
    40021 ttcatcatta atcttttcat tgcaacccgc atattcagcg acaacgaccc aatttgatgc
    40081 ctgctttgca caagccgggc aacgttatct gattgatccc ctgcttctga aaagcattgc
    40141 cactgtagaa agttcactca taccagaccg gataaatcac aacaaagaaa aaggaaaaat
    40201 attaagcacc gattacggac tgatgcaaat taattcatca cacatcccca acctgaaaaa
    40261 acttggcgta ataaaagaca aatcagagct tattgataac ccctgtctca atatacaaat
    40321 tggcgcgtgg attctggcaa cacattttca gaaatgtggc ataaactgga gttgtcttgg
    40381 cagttataac gctggtttca aagaaagtaa cgaacagaaa agaatcaaat acgcacgcta
    40441 tgtctacaat aaatacatgg taaggtaact tatgctaaac agcatattta atacggcgat
    40501 actttgctgt gcaaatatcg tctgtcaatg ctacgcctac aatgaagtaa aattccgttt
    40561 aaataaactt aatgtatctt ataaaaccgg cacagagaaa tattactgtc tgatactgac
    40621 aacgcttgcc gttctgtatc tttcattaaa ccagctatca ctgattcaat ctataatagt
    40681 gattgttttc tatgctttcc ttacattaat ggcttgtata gaccttcttt catttctact
    40741 accacgcctt tataccgtga catttatctt ctctggcctg ttatatcaga catggaataa
    40801 caatatattg tctggtttgt tttgtgcaat gctgatgttc ttcattatgc tgtttgtaag
    40861 actttacttt gcatataaaa acggaacgga aagtttcggc atgggagatg tgctacttat
    40921 tgcaggaact ggcgtatggt ttccaacgcc tgagattgcc tgttcaattg tatttattgc
    40981 cgttatcggc ggaattattt tcttcactct tggcggatta aacaagcaaa aaaaatatat
    41041 cccattcggt ccgttccttt gtggcggaat gtttgtttac tcactcgtac cgggaatatt
    41101 attctgagga ttaagagcaa tgaaaaagac agataaaggt gtatctcttc ttgaggtatt
    41161 acttgtcatc ggcataatgg tgatggttat ccctaaagtt tatgaaaaca ttgaaaacca
    41221 tctgaataat gttcgctggc agaatgcagc agaacacgca aatacctata acaccgctgt
    41281 tcgtaattat gttgctgaca atgcatcaac actacttgct ggctctttac ccaaaacaat
    41341 cacgccagca acactcattc agaaaggcta tctgaaatct ggtttttctg aatccaattt
    41401 tggacaaagc tacattaccg gtattgcaaa gaacagcaaa acatcccgtc tggaagccct
    41461 gacctgtagt aatggcggtc agtccctgtc agaagccgga atgcgctcgg tagcaagcat
    41521 gattgaaggg cttggcggct acatcaacag cagcaagcag gcgattggcg cgggtggcgg
    41581 ctggtctgac acgccttcaa attacgggct gaactgcgcg accgggcata ttgcaatggc
    41641 acttgttggc gctgatttgc aggaaagcga ccgtttgtat cgttactcca taaccaatcg
    41701 tcccgacctt aacaggatgc atacggcgat tgatatgaac agcaacaatc tgaacaacgt
    41761 cggcacttta aacggcaacg ccgccgcgct ctccggcgat atcagcgcac gtaacggtac
    41821 gttctctggc gcaatttcag gaaatacagc cacaaccaac ggcgatatca cttcgaataa
    41881 tggctggctg gtcacaaaaa acagcaaagg ctggatgaac agtacctatg gtggcggctg
    41941 gtatatgtcc gattcgtcct ggttgcgcag cgtgaataat aaagggattt atactggcgg
    42001 ccaggtaaaa ggtggaactg tacgcgctga tggacgcctc tatacaggcg agtatttaca
    42061 gcttgaaaaa acagcaacgg ctggcgcttc ctgctcccct aacgggcttg taggccgcga
    42121 cagtacaggg gcgatac
//
