LOCUS       NZ_CP034757            28640 bp    DNA     circular CON 15-APR-2024
DEFINITION  Enterobacter hormaechei subsp. hoffmannii strain Eh1 plasmid p3,
            complete sequence.
ACCESSION   NZ_CP034757
VERSION     NZ_CP034757.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN10654518
            Assembly: GCF_009834325.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter hormaechei subsp. hoffmannii
  ORGANISM  Enterobacter hormaechei subsp. hoffmannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 28640)
  AUTHORS   Bonomo,R., Fouts,D.E., White,R., Nguyen,K. and Singh,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2018) Informatics Core Services, JCVI, 9605
            Medical Center Drive, Rockville, MD 20850, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: DEC-2018
            Assembly Method                   :: Unicycler v. 0.4.7
            Assembly Name                     :: GCID_DCEE_0001
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 134.2749x
            Sequencing Technology :: Illumina NextSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009834325.1-RS_2024_04_14
            Annotation Date                   :: 04/14/2024 20:45:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,028
            CDSs (total)                      :: 4,920
            Genes (coding)                    :: 4,801
            CDSs (with protein)               :: 4,801
            Genes (RNA)                       :: 108
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 51 of 119
            Pseudo Genes (incomplete)         :: 77 of 119
            Pseudo Genes (internal stop)      :: 18 of 119
            Pseudo Genes (multiple problems)  :: 26 of 119
            Pseudo Genes (short protein)      :: 1 of 119
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034757.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..28640
                     /organism="Enterobacter hormaechei subsp. hoffmannii"
                     /mol_type="genomic DNA"
                     /strain="Eh1"
                     /host="Homo sapiens"
                     /sub_species="hoffmannii"
                     /db_xref="taxon:1812934"
                     /plasmid="p3"
                     /geo_loc_name="USA"
                     /collection_date="2018"
                     /collected_by="Robert Bonomo"
     gene            19..894
                     /locus_tag="EM861_RS24795"
                     /old_locus_tag="EM861_25235"
     CDS             19..894
                     /locus_tag="EM861_RS24795"
                     /old_locus_tag="EM861_25235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098982.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_004098982.1"
                     /translation="MNENVYIGEVIGPDCESVNNKLTVTSKATVQPVALMRLNVFVPSS
                     RPAKGTRTSIDATSVLKDLEFSRREGYDDIRITGERLSMAIDFKVWVGIIEAFSKYGLK
                     TNSIKLTFHEFAGMCRFESKRFDSRLRKSISEALTRIRGKTITFTRSDSEGLQKVSVTG
                     LLKTGELDFANDQVELEADQRLWELYQTDYTVLLRHKPINALTRKEAAQALYTFIESLP
                     TNPVPISFKRIRDRLSLLSPVKEQNRIIKLALKQLQDIGYLDHSITKKGKETFILIHRR
                     SANLKPGTAV"
                     /name="RepB family plasmid replication initiator protein"
     gene            1519..2145
                     /locus_tag="EM861_RS24800"
                     /old_locus_tag="EM861_25240"
     CDS             1519..2145
                     /locus_tag="EM861_RS24800"
                     /old_locus_tag="EM861_25240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010260829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family plasmid-partitioning AAA ATPase"
                     /protein_id="WP_004098977.1"
                     /translation="MIIVLGSQKGGVGKSTLAVSIAAYLMSLGNRVIIVDADDQKSVLT
                     WYNNRPEDLPHIPVTGATGNIKAMLKEHEKSYDFVIADCAGRDSAEMRSGLMAADVFIS
                     PLRPSQMDLDVVPHTCSVFTAAKDFNEDVRGYLVLNMTPTNMFVNEANQAADVLKDYPE
                     MCLASSRVCDRKAHRDAWAESMTIFETQNDKAQQEIESLVKEVIL"
                     /name="ParA family plasmid-partitioning AAA ATPase"
     gene            2142..2444
                     /locus_tag="EM861_RS25400"
     CDS             2142..2444
                     /locus_tag="EM861_RS25400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197636.1"
                     /translation="MRNRANTPSRDEAAFINGGTAGIDNTKVTSERPLAVSKAKPVSIS
                     FFEENLKDIDDLITGEMISGKSRVNRSDVVRAAVEALKSLSKTEISRLIAEAKQR"
                     /name="hypothetical protein"
     gene            complement(2900..3691)
                     /locus_tag="EM861_RS24810"
                     /old_locus_tag="EM861_25250"
     CDS             complement(2900..3691)
                     /locus_tag="EM861_RS24810"
                     /old_locus_tag="EM861_25250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098975.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="WP_032667567.1"
                     /translation="MSGLLSYSHPQQPAQMPVAIDYPAALALRQMALVQDELPKYLLAP
                     EVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLAPPYPFVQLATLKQRTEK
                     AARTAGRAPAGSQAHRLVPLSDHHYVSQLQMMVATLKIPLERRNKRTGRMEKARIWEIT
                     DRTVRTWLSEAVESAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSIS
                     STEVYTKVFALDVAARHRVQFAMPEAEAVALIKKLTPDQST"
                     /name="site-specific integrase"
     gene            complement(3688..4431)
                     /locus_tag="EM861_RS24815"
                     /old_locus_tag="EM861_25255"
     CDS             complement(3688..4431)
                     /locus_tag="EM861_RS24815"
                     /old_locus_tag="EM861_25255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004098973.1"
                     /translation="MTDIQAATESIVAATSHPVSVQLINQGAGIWGNVATGLITGLLTG
                     GITLTGIWLTHYFTLKRERQASEDKMKKELHYIATELVFMLERYAEGCFRVVTDDGQDD
                     DAPQPERKAVTNYPELNLIDVSGDWRTLEPRLMYRIRELPVLQDEAHRAIAYAAEYSDP
                     PWHKDYFRERQYQFTRLGINAVILAVRLRKATGMPETRLTGHDEWSAVSVFRKVWRRER
                     ALRAAEATRNREWNQVVIPDGMSNQ"
                     /name="hypothetical protein"
     gene            complement(4482..4832)
                     /locus_tag="EM861_RS24820"
                     /old_locus_tag="EM861_25260"
     CDS             complement(4482..4832)
                     /locus_tag="EM861_RS24820"
                     /old_locus_tag="EM861_25260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000493378.1"
                     /translation="MFTAFNERNDFSYAFEKIRNAISAPGENNLYAATELGLGILLRKY
                     EQFRQELDAAGELGNWEYDLDTYNHCIAVLQRYFTGNPSGLTERDARIYSHYLQTEHKR
                     FVKLAEELAAGR"
                     /name="hypothetical protein"
     gene            complement(5457..7265)
                     /locus_tag="EM861_RS24825"
                     /old_locus_tag="EM861_25275"
     CDS             complement(5457..7265)
                     /locus_tag="EM861_RS24825"
                     /old_locus_tag="EM861_25275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572050.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="WP_032413492.1"
                     /translation="MTSAFVNEEAVLRIGEVREVSGRTLSVLVDKNKNLSDLFYHGKVL
                     KNVSVGSFIEVKKGFMSLIAKVETEKIVEEKSPVGSGSDSLRFRRYLTASLAGYIDRNG
                     RFTGGTRELPLIGNEVFLMSEEQLHLIHSIAPAGESGLNFSRTDLEDIDITLPISGLLN
                     SHIAIFGNTGSGKSNTLAALYQHGYEALKNLLGEGFRSRSRFLLFDFNGEYGGRSCITR
                     DKVVYNLSTHDEEGDRIPMPAEILLEHEILSVLTDATDKTQKPFLKRVLEFKKRVESKL
                     NPQSYFREILKRRVTETLFGCEKKKSDDLIDLFRPVLKDEDLIADIEFFYNNGGVWRTK
                     TGVYFSNEENTHQCNMYQRAQNYEFPEDIMEELLDYMYVQLIIEYLSSRSNPEHLSPVI
                     NRMSGLKKDIRKIFNTASGGTIWAETNFVVLNLNMVNLTMKKTLPLLMAKWAYSAKKMD
                     KVPSTLHLIIDEAHNILSNTSFRESESWKDYRLETFEEIIKEGRKFGVFVTISSQRPND
                     ISPTIISQAHNYFIHRLINQNDLYAIEKSVSYIDRMTEESIPTLATGTCIFSGVICPMP
                     LKLRINELSFRKKPHSHTLNFEDLML"
                     /name="ATP-binding protein"
     gene            complement(7262..8308)
                     /locus_tag="EM861_RS24830"
                     /old_locus_tag="EM861_25280"
     CDS             complement(7262..8308)
                     /locus_tag="EM861_RS24830"
                     /old_locus_tag="EM861_25280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="WP_058684107.1"
                     /translation="MATYRAYYGQDRDREYFERIFQSANINFIIGSGASLPAISVLGDI
                     ESELEALVRAGNDDEYFSKSESFLDNVWKANNVLLKRSRPAEVILPTLIDDVVSTQNNY
                     AKLMRALEMLLTRRRTGLLPRRINLFTTNYDLFIEDAAVKNNNVILNDGFRQRADIYNR
                     TVFDAKCFYQTIHATGNLYNYSVELPTVNLIKLHGSLSWHSYDKEIYYSIKDMKPVAFN
                     TPKEKQDWVMSHQLVLPRKDKFRETLLENVYYDLLRTYSNELDKEGSLLIVFGFSFADE
                     HIESLTKKALRNATLKIVIFAYNEAAKDLFLGKFRDYSNVDVVFTPGAPLDFKKMNEII
                     TSFLGGMK"
                     /name="SIR2 family protein"
     gene            8492..9184
                     /locus_tag="EM861_RS24835"
                     /old_locus_tag="EM861_25285"
                     /pseudo=""
     CDS             8492..9184
                     /locus_tag="EM861_RS24835"
                     /old_locus_tag="EM861_25285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            <9200..9343
                     /locus_tag="EM861_RS24840"
                     /old_locus_tag="EM861_25290"
                     /pseudo=""
     CDS             <9200..9343
                     /locus_tag="EM861_RS24840"
                     /old_locus_tag="EM861_25290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /name="IS110 family transposase"
     gene            9625..10806
                     /locus_tag="EM861_RS24845"
                     /old_locus_tag="EM861_25295"
     CDS             9625..10806
                     /locus_tag="EM861_RS24845"
                     /old_locus_tag="EM861_25295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4268 domain-containing protein"
                     /protein_id="WP_013023770.1"
                     /translation="MYKIDRQNNSLKSLMEVSFSSLGFRERDHLQEWLANNPQALTKKD
                     DKEDELLIIQKEFAGFDETNERLDLLAIDKKGNLVIIENKLDDSGRDVVWQALKYAGYC
                     ANLRQESVVEIFQLYLTQHEPSEIRPAAEVIAEFMGWESLKEGVLNRKGTQRVIMVAAN
                     FRKEVTNTALWLMQFGIRVQCFKATPYLFAEDVFVDIRQVIPTPEAESYMIGMAQKEAE
                     EQSTSSSSELQQRHYLRREFWSLALEKFRTSTCSLFNNRAPTTDHWLAAGSGVSGVPFE
                     VIFSQKDARIQLNISRSDAVENTWLFERLSERKTHIESQFGGMLNWRLLPERKSCQVVC
                     AKAFDGGNKELWPDIISWMIDGMTRLEKAIRPSLQELAVELKKSGLITEGGDE"
                     /name="DUF4268 domain-containing protein"
     gene            11302..11679
                     /locus_tag="EM861_RS24850"
                     /old_locus_tag="EM861_25300"
     CDS             11302..11679
                     /locus_tag="EM861_RS24850"
                     /old_locus_tag="EM861_25300"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_032667578.1"
                     /translation="MQKNVTPGRRKGCPNYSPEFKQQLVAASCEPGISISKLVLENGIN
                     ANLLFKWRQQWRDGKLLLPSSESPQLLPVTLDATAVQPKSLAEDPGLSISCEVTFRHGT
                     LRLNGTVSEKFLALLIQELKR"
                     /name="transposase"
     gene            11676..12023
                     /gene="tnpB"
                     /locus_tag="EM861_RS24855"
                     /old_locus_tag="EM861_25305"
     CDS             11676..12023
                     /gene="tnpB"
                     /locus_tag="EM861_RS24855"
                     /old_locus_tag="EM861_25305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004966400.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="WP_032667561.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFI
                     FRGRSGSQVKLLWATGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLMEGIDWRQ
                     PKRLLTSLTML"
                     /name="tnpB"
     gene            12074..13612
                     /locus_tag="EM861_RS24860"
                     /old_locus_tag="EM861_25310"
     CDS             12074..13612
                     /locus_tag="EM861_RS24860"
                     /old_locus_tag="EM861_25310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="WP_032667560.1"
                     /translation="MNDASSDDILLLKQRLTEQEALNRALLEKLADREREIDHLQAQLD
                     KLRRMNFGSRSEKVSRRIAQMEADLNRLQQESDALTGLVDDPAVQRPLRQTRTRKPFPE
                     SLPRDEKRLLPAEPCCPECGGSLNYLGEDAAEQLELMRSAFRVIRTVREKHACRRCDRI
                     VQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELSRSLLSGWVDA
                     CCRLLSPLEEALRNYVLTDGKLHADDTPVPVLLPGNKKTKTGRLWTYVRDDRNAGSALT
                     PAVWFAYSPDRKGIHPQTHLAGFSGVLQADAYAGFNELYRDGRITEAACWAHARRKLHD
                     VHVRTPSALTEEALKRIGELYAIEAEIRGMPAEQRLGERQQKAKPRLKSLESWLREKVK
                     TLSRHSELTKAFAYALNQWPALAYYAGDGWAEADNNIAENALRLVSLGRKNWLFFGSDH
                     GGERGALLYSLIGTCKLNSVEPESYLRYVLDVISDWPVNRVSELLPWRVALPTE"
                     /name="IS66 family transposase"
     gene            13723..14937
                     /locus_tag="EM861_RS24865"
                     /old_locus_tag="EM861_25315"
     CDS             13723..14937
                     /locus_tag="EM861_RS24865"
                     /old_locus_tag="EM861_25315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_143212653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II site-specific deoxyribonuclease"
                     /protein_id="WP_005012528.1"
                     /translation="MLMSVFHNWLLEIACENYFVYIKRLSANDTGATGGHQVGLYIPSG
                     IVEKLFPSINHTRELNPSVFLTAHVSSHDCPDSEARAIYYNSRHFGKTRNEKRITRWGR
                     GSPLQNPENTGALTLLAFKLDEQGGDCKEVNIWVCASTDEEDVIETAIGEVIPGALISG
                     PAGQILGGLSLQQAPVNHKYILPEDWHLRFPSGSEIIQYAASHYVKNSLDPDEQLLDRR
                     RVEYDIFLLVEELHVLDIIRKGFGSVDEFIALANSVSNRRKSRAGKSLELHLEHLFIEH
                     GLRHFATQAITEGNKKPDFLFPSAGAYHDTEFPVENLRMLAVKTTCKDRWRQILNEADK
                     IHQVHLFTLQEGVSLAQYREMRESGVRLVVPSSLHKKYPEAVRAELMTLGAFIAELTGL
                     YADIP"
                     /name="type II site-specific deoxyribonuclease"
     gene            complement(14971..16404)
                     /locus_tag="EM861_RS24870"
                     /old_locus_tag="EM861_25320"
     CDS             complement(14971..16404)
                     /locus_tag="EM861_RS24870"
                     /old_locus_tag="EM861_25320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="WP_032667557.1"
                     /translation="MSEFELLAQDLLEKAEAEEQLRQENDKKLLGQVLEIYDQKYVAEL
                     LRKVGKNEWSRETLNRWINGKCSPKALTLAEEELLRKMLPEAPAHHPDYAFRFIDLFAG
                     IGGIRKGFETIGGQCVFTSEWNKEAVRTYKANWFNDPQEHTFNLDIREVTLSDKPEVPE
                     NDAYAYINEHVPDHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFECEAQGTLFFDVARII
                     RAKKPAIFVLENVKNLKSHDKGKTFKVIMDTLDELGYEVADAAEMGKNDPKVIDGKHFL
                     PQHRERIVLVGFRRDLNIHQGFTLRDISRFYPEQRPSFGELLEPVVDSKYILTPKLWEY
                     LYNYAKKHAAKGNGFGFGLVNPENKESIARTLSARYHKDGSEILIDRGWDMATGETDFA
                     NEENQAHRPRRLTPRECARLMGFEKVDGRPFRIPVSDTQSYRQFGNSVVVPVFEAVAKL
                     LEPYILKAVYADSCKVERI"
                     /name="DNA cytosine methyltransferase"
     gene            16553..17250
                     /locus_tag="EM861_RS24875"
                     /old_locus_tag="EM861_25325"
     CDS             join(16553..16802,16802..17250)
                     /locus_tag="EM861_RS24875"
                     /old_locus_tag="EM861_25325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558267.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="WP_108082295.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGAGCRATARIMGVGLNTILRHFKKLRPHSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLGLLSAFEVVVW
                     MTDGWPLYESRLKGELHVISKRYTQRIERHNLNLRQHLARLGRKSLSLSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1 family transposase"
     gene            17637..18191
                     /locus_tag="EM861_RS24880"
                     /old_locus_tag="EM861_25335"
     CDS             17637..18191
                     /locus_tag="EM861_RS24880"
                     /old_locus_tag="EM861_25335"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_159115398.1"
                     /translation="MKTTHERTVYGRNIAENKVTAFVNSTHGETVNLPQNLYKVRNSIL
                     EIFREEAFSGLVDHARNYFSHFVGVPKATRTLYAQILLISESADHCTIIDIRKVPQFLG
                     VAMEFLHVHYTILENAGLLSEQIIDDDVHPVRLYRVFTTFDRNDMQAWLLQSIRNYYLQ
                     SQRQTDFVELVTDLNFNLMDS"
                     /name="hypothetical protein"
     gene            18390..19358
                     /locus_tag="EM861_RS24885"
                     /old_locus_tag="EM861_25345"
     CDS             18390..19358
                     /locus_tag="EM861_RS24885"
                     /old_locus_tag="EM861_25345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="WP_072159722.1"
                     /translation="MKDQITHLPDNADRSVAKQKFKITNWPTYNKALINRGSITFWLDD
                     AAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFILMNVPLR
                     CPDYTSVSKRAKSVNVSFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRK
                     LHLAVDSKTHEIICADLSLNNVTDSEAFPGLIRQTHRKIRSAAADGAYDTRLCHDELRR
                     KKISALIPPRKGAGYWPGEYADRNRAVANQRMTGSNARWKWTTDYNRRSIAETAMYRVK
                     QLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA"
                     /name="IS5 family transposase"
     gene            20069..20455
                     /gene="stbA"
                     /locus_tag="EM861_RS24890"
                     /old_locus_tag="EM861_25350"
     CDS             20069..20455
                     /gene="stbA"
                     /locus_tag="EM861_RS24890"
                     /old_locus_tag="EM861_25350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006796897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbA"
                     /protein_id="WP_001039463.1"
                     /translation="MNKPADLKPRNLSAAVRLRLNEIENWLDRGLTRHEIAEILDSEYS
                     FSVTAKGLEMALYRTRQNRKNVLHNTHDKSSAKGAAESVLHNTQPSEPEAQESEKAESP
                     GIIDKEFFNKIGENFDPKKFNKKF"
                     /name="stbA"
     gene            20464..20655
                     /locus_tag="EM861_RS24895"
                     /old_locus_tag="EM861_25355"
     CDS             20464..20655
                     /locus_tag="EM861_RS24895"
                     /old_locus_tag="EM861_25355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000861580.1"
                     /translation="MKVAVINYSGSVRKTLISSYLLAPRLTGAKFYAVETINQSASDLG
                     IENVTSFKGDDFSRLIEG"
                     /name="hypothetical protein"
     gene            complement(20666..21134)
                     /locus_tag="EM861_RS24900"
                     /old_locus_tag="EM861_25360"
                     /pseudo=""
     CDS             complement(20666..21134)
                     /locus_tag="EM861_RS24900"
                     /old_locus_tag="EM861_25360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            21668..22423
                     /gene="repE"
                     /locus_tag="EM861_RS24905"
                     /old_locus_tag="EM861_25365"
     CDS             21668..22423
                     /gene="repE"
                     /locus_tag="EM861_RS24905"
                     /old_locus_tag="EM861_25365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="WP_000807690.1"
                     /translation="MAEIAVINHKKRKNSPRIVQSNELTEAAYSLSRDQKRMLYLFVDQ
                     IRKSDGSLQEHDGICEIHVAKYAETFGLTSAEASKDIRQALKGFAGKEVVFYRPEEDAG
                     DEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNPYAM
                     RLYESLCQYRKPDGSGVVSLKIDWIMERYQLPQSYQRMPDFRRRFLQASVDEINSRTPM
                     RLSYIEKKKGRQTTHIVFSFRDITSMTIE"
                     /name="repE"
     gene            22692..>23152
                     /locus_tag="EM861_RS24910"
                     /old_locus_tag="EM861_25375"
                     /pseudo=""
     CDS             22692..>23152
                     /locus_tag="EM861_RS24910"
                     /old_locus_tag="EM861_25375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(23927..24253)
                     /locus_tag="EM861_RS24915"
                     /old_locus_tag="EM861_25380"
     CDS             complement(23927..24253)
                     /locus_tag="EM861_RS24915"
                     /old_locus_tag="EM861_25380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201125.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0046872 - metal ion binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C2H2-type zinc finger protein"
                     /protein_id="WP_004201125.1"
                     /translation="MEELFTCPICKLSFGHKARLRKHIKKHTKSLEKNLAKANSTKKAE
                     HEKMLIQERIARTGSAFKNESERNKYFERRRAENPIFDIDTPIRKASFIVNAGAFGLGK
                     SRKN"
                     /name="C2H2-type zinc finger protein"
     gene            24435..24716
                     /locus_tag="EM861_RS24920"
                     /old_locus_tag="EM861_25385"
     CDS             24435..24716
                     /locus_tag="EM861_RS24920"
                     /old_locus_tag="EM861_25385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001568067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001568067.1"
                     /translation="MRVAESIILDALTRGGCIKTFYRISSRQAAESATRIPEGYILESP
                     GEREDIVLSRADFHALEKLLEQKETWEQVVGVTCFGGATWQLRPTVQS"
                     /name="hypothetical protein"
     gene            24770..25381
                     /locus_tag="EM861_RS24925"
                     /old_locus_tag="EM861_25390"
     CDS             24770..25381
                     /locus_tag="EM861_RS24925"
                     /old_locus_tag="EM861_25390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008455304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2913 family protein"
                     /protein_id="WP_000176305.1"
                     /translation="MTLTEKTGHLAWCALVALALARQEQGELSPAQENLFLTRWLAAAL
                     KQRRFSRDVAQDIGWLLNQGRLLGVRAKLADKLGYVWRSCSGELTEQNDMFRLTYALET
                     AKDMGWNYRVMSDREWAGRYALVLNPGVNGVYLLRTNLDAAFDDNGQQTNPLTVRLTGN
                     VTGIMKLLNRCGWQAEPESDASLPHQFSLMARQGVPGKGD"
                     /name="DUF2913 family protein"
     gene            complement(25378..>25509)
                     /locus_tag="EM861_RS25085"
                     /pseudo=""
     CDS             complement(25378..>25509)
                     /locus_tag="EM861_RS25085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /name="ISNCY family transposase"
     gene            complement(25566..26534)
                     /locus_tag="EM861_RS24930"
                     /old_locus_tag="EM861_25395"
                     /pseudo=""
     CDS             complement(25566..26534)
                     /locus_tag="EM861_RS24930"
                     /old_locus_tag="EM861_25395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145103.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(26512..26727)
                     /locus_tag="EM861_RS25090"
     CDS             complement(26512..26727)
                     /locus_tag="EM861_RS25090"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_165450823.1"
                     /translation="MSPVQAKQKQHERYEAVAVQVLRGRAGYKPAVKSRFSKSASSKFL
                     ILSLSAILNLGGNHMLMVFYACSRLL"
                     /name="hypothetical protein"
     gene            26868..27569
                     /locus_tag="EM861_RS24935"
                     /old_locus_tag="EM861_25400"
                     /pseudo=""
     CDS             26868..27569
                     /locus_tag="EM861_RS24935"
                     /old_locus_tag="EM861_25400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            <27621..28247
                     /locus_tag="EM861_RS24940"
                     /old_locus_tag="EM861_25410"
                     /pseudo=""
     CDS             <27621..28247
                     /locus_tag="EM861_RS24940"
                     /old_locus_tag="EM861_25410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502211.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
                     /name="DUF4113 domain-containing protein"
     Typing          20..894
                     /name="rep_cluster_1418"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          21529..21914
                     /name="IncFIA"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.45"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatggat ataactatat gaatgagaat gtttatatcg gcgaggttat aggtccagat
       61 tgtgaaagtg ttaacaataa actcaccgtc acaagtaagg ccacagttca gcctgtagcc
      121 ctgatgagat taaatgtttt tgttccttca agcaggcctg caaagggcac cagaacatca
      181 atcgatgcga cctctgttct caaggatctg gaattctcaa ggcgggaggg gtacgacgat
      241 attcgtataa ccggtgaacg gttgagtatg gccatcgact tcaaggtatg ggtcggtatc
      301 atagaagctt tcagtaagta cggtttaaaa accaacagca ttaagcttac ttttcatgag
      361 tttgctggaa tgtgccgctt tgagtctaag agattcgatt cccgtcttag aaaaagtatt
      421 tcagaagctt tgaccaggat acgtggcaag accattacct ttacccgtag cgactcagag
      481 ggccttcaaa aagtttccgt aacaggtttg cttaagacag gtgaactgga ttttgcaaac
      541 gaccaggtgg aacttgaagc tgatcagcga ctatgggaac tctaccaaac tgattacact
      601 gttctgctac gacataaacc gataaacgct ttaacccgaa aggaagcagc tcaggccctg
      661 tatactttca tcgaaagcct gcctacgaac ccagtcccca tatctttcaa acgaatacga
      721 gacaggctct cattgctctc tccggtaaag gaacagaacc gtatcattaa actggccctc
      781 aagcagttgc aggatattgg gtaccttgac cacagcatca ccaaaaaagg taaagagact
      841 ttcattctga tccaccgtcg ctcagcaaat ctgaaaccag gaacagctgt ataaggtgtg
      901 tcaaaacggg aaagcaacgc gattaaggtg tgttgaaacg ggaggtctct tcttaaacat
      961 cttgataggt gtgttgtagg gggaagcctc gccttaaacg tcttaatagg tgtgttgtag
     1021 cgggatgaga acctgttaaa tgtgtgtttt tatctgtata tacttacgca ccttcccact
     1081 tcaacacacc tttttggata gaagtgagaa gctatcccgc ttctcaccac cttttaccaa
     1141 atttgtctca ccgactcccc acttcgacac accgaagatt caaaggcttc ccactacgcc
     1201 ccactttttg cttcacgcgg tcataactgg ttgatactac cctccctaaa ggtagcctgg
     1261 agttgaaagc cgcattatgt ggttctatgg ggatttcgga taaaggcacc actttgccat
     1321 cttgttatcc tgttatcttg ttatcttgtt atattgttat cctaacatct tactaatttg
     1381 ttaagattca aagataattc aattataaat catgtagtta acaacttaac aagatattaa
     1441 cttaataaag gcattgcaat attgtcgcct gtttggcaat attaagttgt taacttaaca
     1501 acttaatatg aggctatgat gataatagta ttgggtagtc aaaagggtgg ggttggtaaa
     1561 agtacactgg cggtatctat agctgcgtat ctgatgtcac tgggcaatag agtgatcatt
     1621 gtcgacgcag atgaccagaa atctgtattg acctggtaca acaatcgtcc tgaagatctt
     1681 ccccatattc cggttactgg cgcaacaggc aacatcaaag ccatgctaaa ggaacacgag
     1741 aaatcttatg actttgtcat cgcagactgt gctggccgcg acagtgcaga aatgcgtagt
     1801 gggttgatgg ccgctgacgt attcatttct ccgttgcggc cttctcagat ggacctggat
     1861 gtagtgcctc atacatgctc tgtttttaca gcagcaaaag attttaatga ggacgtccgg
     1921 ggatatctcg ttttaaacat gacgcccacg aacatgtttg tcaatgaagc aaatcaggca
     1981 gctgacgtac tcaaggatta tcctgaaatg tgtctggcta gctcccgagt ttgtgatcga
     2041 aaagcgcatc gagatgcctg ggcagaatca atgacaattt ttgaaacgca aaatgacaaa
     2101 gcacaacaag aaatcgaatc gttagttaaa gaggttattc tgtgagaaat agagcaaata
     2161 ctccatctcg tgatgaggca gcgtttatta acggtggtac tgctggtatt gataatacca
     2221 aagtgacttc agagagacca ttggctgtaa gtaaagcaaa accagtgagc atttcctttt
     2281 ttgaagaaaa cttaaaagac attgatgatc ttataacggg tgaaatgatt tcaggtaaaa
     2341 gcagagtgaa tcgttctgac gtagtcaggg cagcggtaga ggcactaaaa agtttatcaa
     2401 aaacagagat atccagatta atcgcagaag cgaaacaacg ataacatctt gttatcttgt
     2461 tatcttgtta tcttgttatc ttgttatctt gttatcttgt tatcttgtta tcttgttatc
     2521 ttgttcaggg tggtaacacc ttttatatcg aggcaacaac ttcgcgatag tgaaaatttg
     2581 cggatggcct cagtcctata cataagggga tatacatgaa ttcaaatact acaatcgcct
     2641 tacatttttc gcttgcatta ctatttacgt tgctatcagt ggctggtagc aaccatgatt
     2701 tagcaggagt tgtatctcaa ttattcctta ttttcatggc tgcatttttt ttctttaggg
     2761 caatgagggc ctttctgaac atcattaatg tgattgatag ctgtaaaagg tgaggcagga
     2821 taagccccca ttaagcttgg actgtttccc acacaagaac tactttaggt tgaaacctgg
     2881 ggtattaccc atagttgacc tatgtagatt ggtctggggt taactttttt atcaacgcaa
     2941 cagcttcagc ttccggcatg gcgaactgca cacgatggcg cgccgcgaca tcgagcgcaa
     3001 acaccttcgt atagacctcc gtcgagctaa tcgatttgtg gcccatcagg ctctgcaaaa
     3061 ccttcagtgg tatgccggca tacagcatgt gcatcgcgta ggagtgacgg aacgtatggg
     3121 gggtcaccgg tactgagaac gtcaccccgt cggccgctgc ggactccacc gcttcgctaa
     3181 gccaggtgcg gacggtacgg tctgtgatct cccagatgcg cgccttctcc attctgccgg
     3241 tgcgcttgtt tcgtctttcc agcggaattt tcagggtggc caccatcatc tgcagctggc
     3301 tgacgtagtg gtgatcggaa agcggaacca gacgatgagc ctggctaccg gcgggagctc
     3361 ggccggctgt cctggccgct ttttcggtgc gctgcttaag cgtggccagc tgcacgaacg
     3421 gatacggtgg cgccagcgaa aaatcccccc gggtcagcgc cagcgcctcg ttgatacgtg
     3481 cgccggtgtt ccagagggtt gccagcagca tcttgcggtg caaatcgggc acataatgga
     3541 gcagggcgct gacttccggt gccagcaggt atttcggtag ttcatcttga acgagcgcca
     3601 tctggcgcag ggccagcgcg gcgggatagt caatggccac cggcatttgc gccggctgct
     3661 gcgggtgaga atatgataag aggccgctca ttggtttgac attccatcag gtatcactac
     3721 ttgattccac tccctgttgc gggtagcttc agcagcgcgc agggctcttt cgcgtctcca
     3781 gactttacga aacacggaaa ctgcagacca ttcatcatga cctgtaagac gtgtttcggg
     3841 catcccggtt gccttgcgca gacggacggc aagaatgaca gcgttgatgc ccaagcgcgt
     3901 gaactgatac tgccgttccc tgaaatagtc cttatgccaa ggagggtcgg agtattcggc
     3961 ggcatatgca attgccctgt gggcctcatc ctggagcacc ggcagttcac ggatgcgata
     4021 cataagacgt ggctctaaag tccgccagtc accggagaca tcgatcagat tcagttcagg
     4081 gtaattcgtg acagcttttc tctcaggctg gggggcatca tcatcctggc cgtcatccgt
     4141 cacaacccgg aaacaaccct cagcataccg ttcaagcatg aataccaact cggtggcaat
     4201 gtaatgcagt tcctttttca ttttatcttc tgacgcctgt ctctcacgct taagcgtgaa
     4261 ataatgtgtc agccagatgc cagtgagtgt tataccccca gtaagcaggc cagtgataag
     4321 cccggttgcc acgtttcccc agatccccgc cccttgatta atcagctgta cggaaaccgg
     4381 atgggatgtc gcagcaacta tactctcagt tgcggcctgt atatcagtca ttgatcattt
     4441 acccctttat attcctgaga aatcccgccc tctgtccgta gtcagcggcc ggcagccagc
     4501 tcttcagcca gtttcacaaa ccttttgtgc tcagtctgca ggtaatggct gtaaatccgg
     4561 gcatcacgtt ctgtcagtcc ggatggattg ccggtgaagt aacgttgcag caccgcaata
     4621 cagtgattgt aggtatcgag atcatattcc cagtttccca gctcaccggc cgcatccagt
     4681 tcctggcgaa actgctcgta tttacggagc agaatgccaa gacctaattc tgttgcagca
     4741 taaagattat tttctcctgg cgcggaaatc gcattacgga ttttttcaaa agcataactg
     4801 aaatcatttc tctcattgaa tgcagtaaac atgtcctttc ctcagttgaa tagttagccg
     4861 tgcaatttta ccacacctca atcatcgtca gatgagtgcc actctgtcgc gacagtgact
     4921 ttcacgagag tgattttcac atactaaaat aataatcagc catataacca cgtaattaaa
     4981 ttaccggatg gccattccgg ccagatccga cttttatgtt attccgcagt ttccggaagt
     5041 gtaccacggt caggaagtaa gcgaagcact gttttctgct gctgcgcgcc gggtcacggg
     5101 gcaggggagg gacacaacat ctagcgtcat cgtcagccag aaacaccgct acatcttgtg
     5161 tttccgggcc gctgcgcgcc ggagccgttc cggcagatcc ggaacttgga gttttcggat
     5221 ctcaggaaaa gaaaggagtg agggataaaa actgacatta ttaaaaatat aaaagcaatg
     5281 cttaaaaagc ataaaagcac tttttgtaat tactgctagt actacaagaa gaatctttag
     5341 tttgaggcgg cgtttatgaa ggtgaccgag ccggacgcga ttccagcatt agctgatctg
     5401 ctcacactga acggggagac aggctgccgt tctgctcaga gaagcggcag ccgtggctaa
     5461 agcattaggt cttcaaaatt cagcgtatgg ctgtgcggct ttttgcggaa agacagctcg
     5521 tttatacgaa gcttaagtgg catagggcag atcacgccac tgaatatgca ggtgccggtt
     5581 gcaagcgttg gaatagattc ttcagtcatg cggtctatgt aggaaacgga tttttcaata
     5641 gcatacagat cgttctgatt tatcaaccgg tgaatgaaat agttatgtgc ctgagaaatg
     5701 atagtcgggg agatatcatt tggtcgctga ctggatatcg tcacaaagac gccaaatttt
     5761 ctgccctcct taattatctc ttcaaacgtt tcgagccgat aatccttcca gctttctgat
     5821 tccctgaacg aggtgttcga aaggatattg tgtgcttcgt ctatgatgag atggagagtg
     5881 gacggtacct tatccatttt ttttgctgaa taggcccatt tggccattaa aagtggtagc
     5941 gtttttttca tggtcagatt gaccatatta aggttcagga caacaaagtt cgtttctgcc
     6001 cagatggttc cgccggatgc agtattgaaa attttacgaa tatctttttt cagtccgctc
     6061 attcggttga tgacaggaga aagatgttca ggatttgagc gacttgaaag atattcaata
     6121 attagctgaa catacatata gtccagcaac tcttccatta tatcttcggg aaattcataa
     6181 ttctgagccc tctggtacat attgcactga tgagtatttt cttcattaga aaagtaaaca
     6241 cctgtcttag ttcgccatac gccgccgttg ttataaaaaa attcaatatc tgctatcagg
     6301 tcttcgtcct taagtacggg acggaataaa tcaatcaggt cgtcactttt tttcttttcg
     6361 caaccaaaca gagtttcggt gacccgccgt ttcagaattt cacgaaaata tgactgaggg
     6421 ttcagcttcg actccactcg ctttttgaat tcaagtactc gcttcaggaa aggtttctgc
     6481 gttttgtcgg tggcatccgt caggacagag agaatctcat gctcaagcag tatctcagca
     6541 ggcatcggaa tgcgatcacc ctcttcatca tgcgtgctaa gattgtaaac aaccttgtcg
     6601 cgcgtaatgc aacttctccc accatattca ccattgaaat caaataaaag aaaccgtgac
     6661 cgacttctga atccttcgcc tagtaggttt ttcagggcct catagccatg ctggtaaagc
     6721 gcggccagag tattggactt gccgctgcca gtattaccga agatggcgat gtgtgagttg
     6781 agaaggccgc ttatcgggag agtgatatca atatcttcga gatcggtgcg cgaaaaattc
     6841 agcccagact cgcccgctgg cgcgatcgag tggataagat gaagttgttc ctcagacatc
     6901 agaaaaactt cattgccgat aaggggtaac tcgcgtgttc cgccagtaaa gcgcccgttc
     6961 cggtcaatgt agcctgccag tgaggctgta agatagcgtc ggaagcgaag cgaatcgctt
     7021 ccgctaccaa caggtgattt ttcctcgaca atcttctcgg tttctacctt tgcaatcaga
     7081 ctcatgaagc cttttttgac ttcgatgaaa ctacctactg aaacattttt gagcacctta
     7141 ccgtgataga aaaggtcact cagattttta tttttatcga caagcacgct gagtgttctg
     7201 cccgatactt cacgaacctc accgatcctt aatactgctt cttcgttaac aaaagcggag
     7261 gtcatttcat acctccaaga aagctggtta taatttcatt catctttttg aagtccaacg
     7321 gagctccagg agtaaaaacc acatcaacgt tggaataatc tcggaattta ccaagaaata
     7381 ggtctttagc cgcctcgttg taagcgaata taacaatttt gagcgtggcg tttcgtagcg
     7441 cttttttggt aaggctttca atatgctcat ccgcaaaaga aaatccgaaa actataagca
     7501 aagagccttc tttatccagc tcatttgaat aagtccgtag tagatcgtaa tacacgtttt
     7561 caagtaaggt ttcacgaaat ttatcctttc gcggcagaac cagttgatgt gacataaccc
     7621 agtcctgctt ctcctttggt gtattgaacg caactggctt catatcctta atggaataat
     7681 agatttcctt atcatagcta tgccaggaaa gggaaccatg cagcttgatg agattcaccg
     7741 taggtagttc cacgctgtaa ttataaaggt ttccggttgc gtgtatggtc tgataaaaac
     7801 atttggcatc gaatactgtc cggttgtaaa tatcagcgcg ctgacggaat ccatcattca
     7861 gaatgacgtt gttattttta accgccgcat cctcaatgaa caaatcatag ttagtcgtaa
     7921 aaaggttgat gcgccgcggt agcaatccag tccgccgcct cgttagaagc atttctaatg
     7981 cccgcatgag cttcgcgtag ttgttttgtg tcgatacgac atcatctatt aaagtaggaa
     8041 ggattacctc tgcgggcctg cttcgcttca ggaggacgtt gtttgccttc catacattgt
     8101 ccagaaaaga ctcagattta ctgaagtatt catcatcatt tccggcgcgg accagagcct
     8161 caagctcgct ttcaatatca cctaacacgc tgattgcagg cagtgatgct cctgagccaa
     8221 tgatgaaatt gatgtttgct gactgaaata tgcgttcaaa gtattcacga tctctgtcct
     8281 gcccgtagta agcccgataa gtcgccacgc tgtgcctttc cttaaatatc gtagataaga
     8341 tttatcttac atgtttcaac aagtgatgca tcctgtttaa atttcattct ctgactcata
     8401 tacgaacgta gctaaacgaa tcaggtaggc agtttcggtg atgctgccaa cttactgatt
     8461 aagcgtatga tggtgttttt gaggtgctcc agtggcttct gtttttatca gctgtccctc
     8521 ctgttcagct actgacgagg tggtgcgaac ggcaaaagca ctgccgaaca tcagcgctat
     8581 ctctgctctc actgccgtaa aacatggcag ctacagttta cttacaccgc ctctcaaccc
     8641 ggtacgcacc agaaaatcat tgatatggcc atgaatggcg tcggatgtcg cgccagtgca
     8701 cgcattatgg gcgttggctt caacacgatt ttacggcact taaaaaactc aggccgtagt
     8761 cggtattctc gcgcatacag ccgggcagtg acgtcatcgt ctgcgcggaa atggacgaac
     8821 agtggggcta cgtcggggct aaatcgcggc agcgctggct gttttacgcg tatgacaggc
     8881 tccggaagac ggttgttgcg cacgtatttg gtgaacgcac tatagcgacg ctggagcgtc
     8941 ttatgagcct gctgtcaccc tttgggtgat atggatgacg gatggctggc cactgtatga
     9001 atcccgcctg aagggaaaac tgcacgttat cagcaagcga tatacgcagc gaaatgagcg
     9061 gcataacctg aatctgaggc agcatctggc aaggctggga cggaagtcgc tgtcgttctc
     9121 aaaatcggtg gagttgcatg acaaagtcat cgggcattat ctgaacataa aacactatca
     9181 ataatttgga gtcattacct acgatgagat gtgcctgcgg ggtaaaccta aaatggtggc
     9241 cattggcgcg ctgatgcgga aactggtgca ctggtgttat ggcgtcctga agaccggaac
     9301 cgtttttaat gacgaaggtc tgaaacaagt actgtcaacc tgactatacc tggctggcat
     9361 taaactcaat gtaacgctca cagcagtaag tgagcgcagt ccgctatgag cgatctacgg
     9421 acattgctag cagcattagg tgtgagtcaa cagggagctt gtcagctcac gctaccggag
     9481 gatatgataa atggggaatt gagaaattta aatttcaata taaacaaaca attatcttct
     9541 tagcgtacgt ttccgttcca ttaccctcaa acccaaataa gataattctg ccagaagcaa
     9601 aacaatcagg atgtgagata gaaaatgtat aagattgatc ggcaaaacaa tagcctcaag
     9661 tcgctcatgg aagtctcttt tagcagtctt ggttttcgcg aacgcgatca tttgcaagag
     9721 tggctggcaa acaatcctca agcgttgact aagaaagatg ataaagagga cgaactttta
     9781 attattcaga aagagtttgc tggttttgat gagactaacg aacgtctcga tctgctggct
     9841 atcgacaaaa aaggcaactt ggtcattatc gagaataaac ttgatgattc agggcgtgac
     9901 gtggtctggc aggcgctgaa gtatgcgggt tactgcgcca accttcgtca ggaaagcgtt
     9961 gtcgaaattt ttcagcttta tcttacacaa catgaaccct cggaaatccg ccctgcggca
    10021 gaagttattg cagaatttat gggctgggaa agtttgaaag aaggtgtgct caatcgaaaa
    10081 gggacacagc gcgttatcat ggtagcggcg aatttccgca aagaagttac caatactgca
    10141 ctatggctaa tgcagtttgg catccgagtg caatgcttca aagcgacgcc gtacctcttt
    10201 gccgaggatg tttttgtcga tatacggcag gtcattccga ctcctgaagc ggaatcctac
    10261 atgattggaa tggcgcagaa agaggcagaa gagcagtcca cctcaagcag tagcgaactg
    10321 caacaacgac attatttacg ccgtgagttc tggtcgttag cactggaaaa attccgtacc
    10381 agcacatgtt cattatttaa caaccgagca cctacgacag accattggct ggcagcgggt
    10441 tcgggggtta gtggcgtgcc ttttgaagtg atcttctcgc aaaaagatgc tcgcattcag
    10501 ctcaatattt cacgttcaga tgcggtagaa aatacatggc tgtttgagcg tctgtcagag
    10561 cgcaaaacgc atattgagtc gcagtttggt gggatgctca attggcgact actgcctgag
    10621 agaaaaagct gccaggttgt ttgtgcaaaa gcatttgacg gcggaaacaa agaactttgg
    10681 cctgacatca ttagctggat gattgatggt atgacccgtc tggaaaaagc aattcgcccg
    10741 agcttacagg agctggcggt tgagctgaaa aagtcaggtc tgatcaccga aggtggggac
    10801 gagtagtatt aagtagagtg accctgaccc gtgatccacg caaactgtaa ttaacaactt
    10861 ccgctcctgg cacaaagcag acgttaaagt ctacacttcc tgatgccgcg tcagcggcat
    10921 ggaggcgcca gatgaggtta catgtgtctg tggagtcaaa tggcgccgaa agcccggcgt
    10981 agccggttgc cgggctataa attctgccac cctaccccct gccctgatta gccttaaccc
    11041 gctaacagca atgaagaagt caaagtaatc ccttttaacc ccggtgagcg ggctttacgg
    11101 cgtttacgac gtaaagggcg tgatttccgg ggccttagcg gcggcagctt gctgctgacg
    11161 cttaggggga tgttcatcaa ctatctaagc gacaccaggg aacttaacgg taagcgtaca
    11221 gcgagagccg tctggtcata acctgatgta ttcgacaaag tggtgtccac caaataagta
    11281 gtgggaacca aagtgtcaga tatgcagaaa aatgtgactc ccggcaggcg taagggctgc
    11341 cctaattatt ctcctgagtt taagcagcag ctcgttgctg cctcctgcga acccggaata
    11401 tccatctcaa aactggtgct tgaaaacggc atcaacgcta atttgttatt taaatggcgc
    11461 cagcagtggc gcgacggaaa gctactgtta ccttcctcag agagtcctca gctacttcct
    11521 gtgactctcg atgccactgc cgtacagcca aaatcgctcg cggaagaccc ggggctcagt
    11581 atcagctgtg aggtaacgtt ccggcacggg acgcttcgcc tcaacggtac tgtcagcgaa
    11641 aagttcctgg ctctgctgat acaggaactg aagcgatgat cccgttacct tcaggcacaa
    11701 aaatctggct ggtagccggg atcaccgaca tgcgcaacgg cttcaatggt ctggccgcaa
    11761 aggtgcagac agcgctgaaa gatgacccga tgtccggcca cgtcttcatc ttccggggac
    11821 gcagcggcag tcaggtcaaa ctgctgtggg ccaccggcga cgggctgtgc ctgctgacaa
    11881 agcggctgga acgtggtcgc ttcgcctggc cctcagcccg cgatggcaaa gtgttcctga
    11941 ccccggcgca gctggcgatg ctgatggaag gtatcgactg gcgacagcca aagcggttac
    12001 tgacctccct gaccatgctg tagctctctt taatcctggt tgtcgcagaa taagcctggt
    12061 aaaatacggg cttatgaacg acgcctcttc tgacgacatc cttctgctga aacagcgcct
    12121 gaccgaacag gaagcgctga accgtgctct gctggaaaaa ctggccgatc gtgaacgcga
    12181 aatagaccat ctgcaggcgc agctggataa gctgcgccgg atgaacttcg gcagccgttc
    12241 cgaaaaggta tcccgccgta tcgcgcagat ggaagctgat ctgaaccggc ttcagcagga
    12301 aagcgatgcc cttaccggtc tggttgatga ccccgcggtg cagcgcccgc tgcgtcagac
    12361 ccgcacccgt aaaccgttcc ccgaatcgct tccccgtgat gaaaagcggt tgttacccgc
    12421 agagccctgc tgtccggagt gtggtggttc gctgaattac ctgggtgagg atgccgccga
    12481 acagctggag ctgatgcgca gcgccttccg ggttatccgt acggtgcgcg aaaagcatgc
    12541 ctgtcgtcgg tgcgaccgca tcgtgcaggc cccggcgcct tcgcgcccca tcgagcgggg
    12601 catagctgga ccggggctgc tggcccgcgt gctgacctca aagtatgcag agcacacacc
    12661 gctgtatcgc cagtctgaaa tatacggccg ccagggcgtg gagctgagtc gctcactcct
    12721 gtcgggctgg gtggatgcgt gttgccggct gctgtcgccg ctggaagagg cgcttcgaaa
    12781 ctatgtgctg actgacggca agcttcatgc cgatgacacg ccggtgccgg tgctgctacc
    12841 gggtaataag aaaacgaaga cggggcgctt atggacgtac gttcgtgacg accgtaacgc
    12901 cggatccgcg ctgacgccgg cggtgtggtt cgcttacagc ccggacagaa aaggcatcca
    12961 cccgcagacc catcttgccg gcttcagcgg tgtgctgcag gcagatgcat atgccgggtt
    13021 caacgagctg taccgcgatg ggcggataac ggaagctgcc tgctgggctc acgcccgccg
    13081 taagctccac gatgtgcacg ttcgcacccc atcagcgctg acggaggaag ccctgaaacg
    13141 gatcggcgag ttgtatgcca tcgaggcgga aataagggga atgccggcag aacagcgact
    13201 cggcgaacgt cagcagaaag ctaaaccgcg actgaaatcc ctggaaagct ggctgcgaga
    13261 aaaggtgaaa accctgtcgc gacactcaga gctgacaaaa gcgttcgcgt acgccctgaa
    13321 ccagtggccg gcactggcgt actatgcagg cgatggctgg gctgaagcag ataataacat
    13381 cgcagaaaat gccctgcggc tggtcagtct ggggagaaaa aactggctgt tcttcggttc
    13441 tgaccacggt ggtgagcggg gagcactgct gtacagcctg atcgggacat gcaaactgaa
    13501 cagcgtggag ccagaaagct acctccgcta tgttcttgac gttatttctg actggccggt
    13561 caatcgggtg agtgaactgc tcccctggcg cgtagcactg ccgactgaat aacacatccc
    13621 cgtcaatacg gctctcgctg tacgcttacc ctgtaacagc ctttctggct gtttgtatat
    13681 aattatgaaa aaatggtgag tagagtttca gggtaacagg ggatgcttat gtcggttttc
    13741 cacaactggc tacttgagat cgcatgtgag aattacttcg tctacatcaa acgcctttcc
    13801 gccaacgata ccggcgcaac aggtggtcac caggtagggc tttatatccc ttcaggtatc
    13861 gttgaaaaac tgtttccgtc tatcaaccat acccgtgaac tgaacccttc ggtttttctc
    13921 accgcacatg tgtcatcgca tgattgccct gacagcgaag cccgggcaat ttattataac
    13981 agccgtcatt ttggtaaaac ccggaatgaa aaaaggatta cccgctgggg tagaggcagc
    14041 ccacttcaga atcctgaaaa tacaggggct ctgacgctac tggctttcaa gcttgatgag
    14101 caaggggggg actgtaagga agtaaatatt tgggtatgcg ccagcactga tgaagaggac
    14161 gtcattgaga ccgctattgg tgaagttata cccggagcgc ttatatccgg ccccgcagga
    14221 cagattctag gcggactatc tctacagcaa gcgccagtaa atcataaata tattctacct
    14281 gaagactggc acctgcgctt tccgtcggga agtgaaatta ttcagtatgc agccagccat
    14341 tatgtgaaaa attcccttga tcccgatgag caacttcttg accgccggcg cgtggagtac
    14401 gacatatttc tattggttga ggaactgcat gttctggata tcatccggaa aggatttggc
    14461 tctgtggatg aatttattgc gctggccaat tctgtcagca atcgccgtaa atccagagcc
    14521 gggaagtcgc tggaactgca cctggagcat ctattcattg agcacggcct gcgacacttt
    14581 gcgacgcagg ccatcacaga aggtaataaa aaacccgatt tccttttccc ttccgcaggg
    14641 gcttaccacg atactgagtt tcccgtagaa aatctgcgca tgctggcagt caagactacc
    14701 tgtaaggatc gctggcgtca gatactgaat gaggccgata aaattcatca ggtgcatctg
    14761 tttacactcc aggagggagt ttctctggct caatatcggg agatgcggga gtcgggtgtc
    14821 agattggtcg tgccatcatc tctgcacaaa aaatacccgg aggcggtgag agctgagcta
    14881 atgacgctag gtgcgtttat tgctgagctg acagggcttt acgcagatat tccatagatt
    14941 atctcccggc ataaataccg ggaggagcga tcagattcgt tcaaccttgc acgaatcggc
    15001 ataaaccgct ttcaggatat aaggttcaag cagtttggct acggcttcaa acacgggcac
    15061 cactacggag ttaccgaact gcctgtacga ctgagtgtct gacacaggaa tgcgaaaagg
    15121 cctgccatct actttttcaa aacccataag gcgcgcgcac tctcgtggag tcagcctgcg
    15181 gggccgatgc gcctgatttt cttcgttcgc gaagtctgtt tcacctgtgg ccatatccca
    15241 gccacggtct atcagaattt cagacccgtc tttgtgatag cgagcagaaa gcgtacgggc
    15301 aatgctttct ttattttcag gattaacgag gccaaaaccg aatccgttac ccttagctgc
    15361 gtgctttttg gcgtagttat agagatactc ccagagtttc ggcgtcagta tatatttgct
    15421 gtcaaccacg ggttccagca gttcgccaaa tgacggacgc tgttccggat aaaaacgact
    15481 aatatcgcgc agggtaaagc cctggtgaat gttcagatca cgacggaaac cgaccaaaac
    15541 gatacgttct cggtgctgag gtaaaaagtg ctttccgtcg ataactttag gatcgttttt
    15601 gcccatctca gctgcatccg caacttcata gcctagttcg tcgagggtat ccatgatgac
    15661 tttaaaggtt ttacccttgt catggctctt caggttttta acgttttcaa gaacaaagat
    15721 ggcaggtttt tttgcgcgga taatacgcgc cacatcgaag aaaagcgttc cctgagcctc
    15781 acattcgaaa ccatgcgcgc gcccgagcga gtttttcttg cttacgcccg caaggctgaa
    15841 cggttgacag gggaaacctg ctagaagtac atcatgatcc ggcacatgct cattaatgta
    15901 agcataggca tcgttttcag gtacttcagg tttatcactg agcgtgactt cccgaatatc
    15961 gagattgaaa gtgtgttcct gaggatcgtt aaaccagtta gctttatatg tgcgcacagc
    16021 ctctttattc cattcactgg taaaaacgca ctggccaccg atggtttcga agcccttccg
    16081 tatacctcca atcccagcaa acaggtcaat aaaccggaag gcatagtcag ggtgatgtgc
    16141 aggcgcttcc ggaagcattt ttcgtagaag ttcctcttcg gctaacgtca gcgccttagg
    16201 tgagcactta ccattaatcc agcgattaag agtctcgcga ctccactcat ttttaccaac
    16261 ttttctaagc agttcagcca cgtacttctg gtcatagatt tccagcacct gcccgagcag
    16321 ctttttatca ttttcctgtc gcagttgttc ttccgcttct gctttctcaa gcagatcctg
    16381 cgccagtaat tcaaattcag acatattgcc tccattgggt cttatgggtg aaactgtatc
    16441 actcatttga cccagattga atgtttttat ctggatattt aaacaggttt attgttaggt
    16501 gatgctgcca acttactgat ttagtgtatg atggtgtttt tgaggtgctc cagtggcttc
    16561 tgtttctatc agctgtccct cctgttcagc tactgacggg gtggtgcgta acggcaaaag
    16621 cactgccgga catcagcgct atctctgctc tcactgccgt aaaacatggc aactgcagtt
    16681 cacttacacc gcttctcaac ccggtacgca ccagaaaatc attgatatgg ccatgaatgg
    16741 tgctggatgc cgggcaaccg cccgcattat gggcgttggc ctcaacacga ttttacgtca
    16801 cttaaaaaac tcaggccgca ttcggtaacc tcgcgcatac agccgggcag tgatgtgatt
    16861 gtctgcgctg aaatggacga acagtggggc tacgtcggtg ctaaatcgcg ccagcgctgg
    16921 ctgttttacg cgtatgacag gatacggagg acggttgtgg cgcacgtatt cggtgaacgc
    16981 actctggcca cgctggagcg tcttctgggc ctgctgtcgg cctttgaggt cgtggtatgg
    17041 atgacggatg gctggccgct ttatgaatca cgcctgaagg gagaactgca cgttatcagc
    17101 aagcgatata cgcagcgcat tgagcggcat aacctgaatc tgaggcagca tctggcaagg
    17161 ctgggcagga agtcactgtc gctatcaaaa tcggtggagc tgcatgacaa ggtcatcggg
    17221 cattatctga acataaaaca ctatcagtaa gttggagtca ttacctgact ctagatagtg
    17281 actaaactca caattgttaa tactcacaga acgggtatca aatggagcta gaatcttaag
    17341 ggcgaatgga gcaaactgag ataaatattt agataaggtc tttagataat taaggaaacg
    17401 ctaatgagcc gtcttaaccc taaatcaaca actttaagaa ccctttttct ccgttcggga
    17461 aatcaatgtg cctttccagg atgtgatgtg gataataatc ttactgtcgg aaagtctgcc
    17521 atattacagc tgaagtcggg cgttataata agtaacatga atcgtcgtag taacctaatt
    17581 cttcttttca aaatcacaaa taatgatata tgtaccctgt acaagttttg cattcaatga
    17641 aaacgacgca cgagcgtacg gtttatggaa gaaatatcgc agagaacaaa gttacagctt
    17701 tcgtcaattc aacacatggt gaaacggtaa atttacctca aaatctatac aaagttcgaa
    17761 actcaatctt agaaattttc cgagaagagg cattttctgg attagttgat catgcgagaa
    17821 attatttttc tcattttgtc ggagttccta aagcaactcg tacactttac gctcaaatcc
    17881 ttttgatttc agaaagcgct gaccactgta cgattattga tattcgaaaa gtaccgcaat
    17941 tccttggtgt ggcaatggaa tttttacatg tacattacac aatacttgaa aatgcagggt
    18001 tgcttagtga gcaaattata gatgacgatg tccatccagt ccgcctctat cgcgtattca
    18061 ctacttttga tcgaaatgac atgcaggctt ggttgttaca aagtataaga aattattatc
    18121 tgcaaagcca acgacaaacc gattttgtgg aactggtaac tgatcttaac tttaacctta
    18181 tggattcata attacttatt tttatagaag aatattccgt tttgcgagaa tggagccttt
    18241 gcttatagtt tccagctggt taatgcgaag aagtcaaatt gcaggcactg ggtgagtaag
    18301 agcctgaaag ggtcctcagt gtcgtttgaa tcctcttaat aatctaatgc gctgaccggc
    18361 tttgttgaat aaatcgaact tttgctgagt tgaaggatca gatcacgcat cttcccgaca
    18421 acgcagaccg ttccgtggca aagcaaaagt tcaaaatcac caactggccc acctacaata
    18481 aagccctcat caaccgtggc tccataactt tctggctgga tgatgcagct attcaggcct
    18541 ggtatgagtc ggcaacgcct tcatcacgag gaagacctca gcgctattct gatctcgcca
    18601 tcaccaccgt tctggtcatt aaacgcgtgt tcaggttgac cctgcgggct gcacagggtt
    18661 ttattgattc catttttata ctgatgaatg ttccgttgcg ctgcccggat tacaccagtg
    18721 tcagcaagcg cgcaaagtcg gttaatgtca gtttcaaaac gcccacccgg ggtgaaatcg
    18781 cacacctggt aattgattcc accgggctga aggtcttcgg tgaaggcgag tggaaagtca
    18841 aaaagcatgg ccaggaacgc cgccgtatct ggcgtaagct gcatctggca gttgacagta
    18901 aaacacatga aatcatctgc gctgacctgt cgctgaacaa cgttacggac tcagaggcct
    18961 tccccgggtt aatccggcaa acccaccgga aaatcaggtc agccgccgcc gatggcgctt
    19021 acgatacccg gctatgtcac gatgaactgc ggcgtaagaa aatcagcgcg cttatccctc
    19081 cccgaaaagg tgcaggttac tggcccggtg aatatgcaga ccgtaaccgt gcagtggcta
    19141 atcagcgaat gaccgggagt aatgcgcggt ggaaatggac aacagattac aaccgtcgct
    19201 cgatagcgga aacggcgatg taccgggtaa aacagctgtt cgggggttca ctgacgctgc
    19261 gtgactacga tggtcaggtt gcggaggcta tggccctggt acgagcgctg aacaaaatga
    19321 cgaaagcagg tatgcctgaa agcgtgcgta ttgcctgaaa gcgtgcgtat tgcctgaaaa
    19381 cacaacccgc tacgggggag acttacccga aatctgattt attcaacaaa gcccagcgcc
    19441 gcaaatactc tgaccgatta ccacctgaaa ccaggtctat ataggccaaa agttcatctg
    19501 atacttttgc ggttattgtt ggcattcagt cctcactttg tgcatttttt aaacgaaaaa
    19561 agggtgtcta atacggtgaa atcatagtat taccaaagta ataaataaaa aatgtttttt
    19621 aaatcgtaag ttagattaga tttgtaatac accggtaata cagcatggtt aaatttggtt
    19681 ttttttcttt taaatcagtg agatagcgtg atttatcacg ctgcgttagg tgtatagcag
    19741 gttaagggat aaaaaatcat ctttttttgg tagggcgatc tccgtaggtt aagggtcatt
    19801 tggctaaaaa gcgtcctatt ctttgatggt catgcttgca tgaccatctg agcaaccaaa
    19861 aactacagat aaactacaga taaactacaa aaaacgtttt gccttagtgt tggaagacta
    19921 caaatagact acaataaaac tacaaaaaaa ctacaaaaaa cgtgacagac tacaaataga
    19981 ctacaagaaa actacagata aactacaaaa ctcgattgac cccttcttac gagtgttgta
    20041 gagtcatttt catacaacgg agggggttat gaataaacca gcagatctga aaccccgcaa
    20101 cttatcggct gctgtcagat tgcgcctaaa tgaaatcgag aactggctgg acagagggct
    20161 aacgcggcat gaaattgctg aaatcctcga cagcgaatac agcttttcgg taacagccaa
    20221 agggcttgag atggcactgt atagaacgcg gcaaaaccga aaaaatgtat tgcacaatac
    20281 acatgataag agtagcgcga agggtgcagc ggaaagtgta ttgcacaata cacaaccgtc
    20341 tgagcctgaa gcgcaggaaa gtgaaaaagc agagagtccc ggcattattg ataaagaatt
    20401 cttcaataaa atcggtgaga atttcgaccc taagaagttc aacaaaaaat tctgaggtga
    20461 tttatgaaag tagcggtaat taattacagt ggcagtgttc gtaaaacctt aatttcatct
    20521 tacctgttag ccccgcggct gactggtgca aagttctatg cggtagagac tatcaaccag
    20581 tctgcttccg atctgggtat tgaaaatgtg accagtttta aaggtgacga cttctcacgt
    20641 ttgattgagg ggtaatgact ccaacttact ggtagtgttt tatgttcaga taatgtccaa
    20701 tgactttgtc atgcagttct cccttcaggc gtgattcata aagcggccag tcatccgtca
    20761 tccataccac gacctcaaag gccgacagca ggcccggaag acgctccagc gtggccagag
    20821 tgcgttcacc gaagacgtgc gccacaaccg tcctccgtat cctgtcatac gcgtaaaaca
    20881 accagcgctg gcgtgattta gcgccgacgt aaccccactg ttcgtctatt tccgcgcaaa
    20941 caatgacgtc actgcccggt tgtatgcgtg agtttaccga ctgcggcctg agaggcggtg
    21001 taagtgaact gtagctgcca tgttttacgg cagtgagagc agagatagcg ctgatgtccg
    21061 gcagtacttt taccgttacg caccacgcct tcagtagctg agcaggaggg acaagtgatg
    21121 gagatggaag ccactggagc acctcaaaac caccatcata cactaaatca gcaagttggt
    21181 agcattaccc agaactggac agaatagtct gtatgtctaa cttctggcca cagatataat
    21241 cgagccagca gtgctcgccg cagccgagcg acagggcgaa gccccgagtg agcgaggaag
    21301 caccatggaa cagtactcat aaattctgca tacgctcaat gcctgcaaaa tcacctccca
    21361 taggggttat ccacttatcc acggggatat ttttataaga tctttttaaa tagttgttag
    21421 atttttattt ttagaatgcc cacaggcctt tatccatgcg ggttccagag agggatctgt
    21481 gacaaaacgc cctttcagtg tgacaaatca ccctcaaata gccgccattt ctgtgacaag
    21541 ttgcccttaa ccctgtgaca aattgccctc aggaagcgtt gcttttcaca aagttatcca
    21601 tccctgttga ctctgtttta tgaagtgtga caatcttaaa gtctgtcaca cttcgcatgg
    21661 acctgtcatg gcggaaatag cggttataaa ccataaaaaa cgtaaaaata gcccgcggat
    21721 tgtccagtct aacgagctga ctgaggcggc atatagtctc tccagggatc aaaagcgtat
    21781 gctgtatctg ttcgttgacc agatcagaaa atccgacggc tccctgcagg aacatgacgg
    21841 catctgcgaa attcacgttg ctaaatacgc tgaaacattc gggctgacct ccgctgaagc
    21901 cagtaaggat atacgacagg ctttaaaagg ttttgcgggt aaggaagtgg ttttctatcg
    21961 ccctgaagag gatgccggcg atgaaaaagg gtatgaatcc tttccctggt ttattaaacg
    22021 tgcgcacagc ccatccagag ggctttacag cgtacatatc aacccatatc tgattccctt
    22081 cttcatcggg ttacagaacc ggtttacgca gttccggctc agtgaaacaa aagagattac
    22141 caatccgtac gccatgcgtt tatacgaatc tctgtgccag taccgtaaac ctgatggctc
    22201 aggtgtcgtg tccctgaaaa tcgactggat catggaacgc taccagctac ctcaaagtta
    22261 ccagcgtatg ccggactttc gccgccgttt cctgcaggca agtgttgacg agatcaacag
    22321 ccggacacca atgcgccttt cttacatcga gaaaaagaaa ggccgccaga cgacgcatat
    22381 cgtattttcc ttccgtgata taacctccat gacgattgaa tagttgaggg ctatctgtca
    22441 cagatttaag ggtggttcgt cacatttgat ctggaaagtt gagggtgatt tgtcacagtt
    22501 ttgctgttcc ctccctggca tcctgcgctt actcatagtt tttttggctg taaccggtag
    22561 tggagccaga attgagggca atttgtcacc ctatcctgag ggtagtttgt cacactagat
    22621 tttctccctc ttcccgggta atggtgccaa cttactgatt tagtgtatga tggtgttttt
    22681 gaggtgctcc cgtggcttcc atctccatca cttgtccctc ctgctcagct actgaaggcg
    22741 tggtgcgtaa cggtaaaagt actgccggac atcagcgcta tctctgctct cactgccgta
    22801 aaacatggca gctacagttc acttacaccg cctctcagcc cggtacacac cagaaaatta
    22861 ttgatatggc catgaatggc gtcggatgtc gcgccagtgc acgcattatg ggcgttggcc
    22921 tcaacacgat tttacgacac ttaaaaaact caggccgcag tcggtaaact cacgcataca
    22981 accgggcagt gatgtgattg tctgctctga aatggatgaa cagtgtggtt acgtcggcgc
    23041 taaatcacgc cagcgctggt tgttttacgc gtatgacagg atacggagga cggttgttgc
    23101 acacgtcttc ggtgaacgta ctatggccac gctggagcat cttctgagcc tgccgtcgga
    23161 ctttcagggc gcgtggttcc ttttaaacac cagctctgta tctcttttaa agatccttca
    23221 ataaatcctg taaacacata acctgttcat cgcctgccct gtggacaggc tcgggagaat
    23281 gcccgccctt gcagcgacct gacggtcgcg ccggttcggc aacacctgag agagctccca
    23341 tcgcttcgcg acgggccccg accggagaac cactagttac agcattcaaa aggaaagtta
    23401 atcaaaaccg gcgccggttt gtcggccaat gcccctccca cactgcaaag cgcccgcccc
    23461 cggccgaagg ccggtagctt ttaatgatgg gtgttgtaac tattcttctt catcgctgtg
    23521 ggtggagctg cggtcagttg tctggtacac gctcgtaagc ggccctgcgg cccgctaacg
    23581 cggagatacg ccccgactgc ggctaacgcc ttgtcgggac tccgaccgcg tacagcagct
    23641 tctgtatcgt ttttagcggg tttgttctgg gcttagcagt gtggggattt tacggctgaa
    23701 gccgtaataa agctttgtcc tcgcctagct gggtctcagg cgcatggcgc ctcccatgcc
    23761 tgacgcgcat caaaacccgt ccccctgcgc cacttgtgtc tgacgcacgc gagagtccgc
    23821 tgcggcaaaa aaacaagaag agagctagac gaaggtcgct cagctccccg taatttttta
    23881 tatactcacc acggggacat tagatctgct tttgccaaaa aaacggctag ttttttctgg
    23941 atttacccaa accaaaggca ccggcattca ctataaacga ggcctttctg atcggcgtat
    24001 cgatatcaaa tatggggttt tcagcacgcc ttctttcaaa gtacttattt ctctccgatt
    24061 catttttaaa agcgctacct gtccttgcaa tcctctcctg aataagcatc ttttcatgct
    24121 cagccttttt ggttgagttg gccttagcga gattcttttc aagggatttc gtatgctttt
    24181 ttatatgctt tctcaaccta gctttatggc caaatgagag tttacatatc ggacaagtga
    24241 ataattcttc cataagcttc atgagtgtaa ggggaaggtt atatttacca tagcattcct
    24301 tgtccgaact gccatgcgat ggtccaccgg ggcaatgagg caaagccgtt gtctgtggaa
    24361 gcactacgcg gcatgatgag cgtcgccagt tgcacaccgg caaagacgtg aaacactttt
    24421 aaccggagcc agtcatgcgc gttgccgaaa gcatcatcct cgatgccctc actcgcggag
    24481 gatgcatcaa aaccttttac cgcatatcct cacggcaggc tgctgaatcg gccacgcgga
    24541 tacctgaggg gtatattctg gagtcgcccg gcgagcggga agatattgtg ctctcgcgcg
    24601 cggactttca tgcgctggag aagctgctgg agcagaagga aacctgggag caggtggtcg
    24661 gtgtgacctg ttttggtggg gcaacatggc agctgagacc gactgtacag agctgaacaa
    24721 ctgagattta agaccaggga atcagtaaga ctgaagggag gtatctgtta tgacgctgac
    24781 agaaaaaaca ggccatctgg catggtgtgc actggtcgcg ctggcactgg ccagacagga
    24841 gcagggagaa ctctctcccg cacaggaaaa tctctttctc acccgctggc tcgcggcagc
    24901 actgaagcaa cggcgattct cgcgcgatgt ggcacaggat atcgggtggt tactgaatca
    24961 ggggcgtttg ctgggtgtga gagctaagct ggccgacaaa ctgggctatg tctggcgctc
    25021 ctgcagcggc gagttgactg aacagaacga catgttccgc ctgacgtatg cgctggaaac
    25081 agcgaaagac atgggctgga attaccgcgt aatgagcgac agagaatggg ccggacgata
    25141 tgctttggta ctcaatcctg gagtaaacgg tgtttatctc ttacggacaa accttgatgc
    25201 cgcttttgac gacaatggcc aacagacaaa tccgctgaca gtacgtctga cagggaacgt
    25261 aactgggata atgaaactgt taaatcgctg tggctggcag gctgagcctg agtctgatgc
    25321 ctccctgccc caccagtttt cactgatggc ccggcaggga gtgccaggaa agggggatta
    25381 gtggcggatt tgtgccaggt tatcttcagt cagaccggtc attttcatga cagtattgcg
    25441 gtcaatgccg ttctgcagca tggtacgggc aattttcaga gtggcctgac gctcaccttc
    25501 tgaacggcct attagcgtgt gctccggtgg tttgcacatg cgcaaatttt tcagcccaaa
    25561 gggggctaat catcacgggg attacgttca aatcccctgc gccctcttgc tgcccattca
    25621 gcattgagta ccacgtaacg ctcccagcgt tcacgcagct gtgcgagctt tagcggtact
    25681 tctttggtga caaaggcttc cggtatttca aagtcatcaa gatgcccttc caggtataca
    25741 tgtacgcctt ccaacacatc aatcagagtg atgttgttac tttgttgccc ttcaagaagc
    25801 ggcccctgcc agctatgcca gaaggcctga tggcgcagac agctttcgtc attcgcgagc
    25861 ctccataaat ccataaagat tcctcgtgca actttgaacg gctgttcatc aaactgttcg
    25921 atgagaaaga aataacacgg gatcttgagc gcgttaatac gcgcaatttc acttcagcat
    25981 cacggcgcaa aggcaatcag attgctaaaa gcgcgagcgc atacaggcga cagggttcac
    26041 ccttaccttt tcattcattt caggcatgcc ggggccggtt gcttctacat aaaacggggc
    26101 ggtatacagg taaagctttt tcccctgaaa atcagaacgg tcaaagcctc cggggcggtc
    26161 gataatatcc accacatttg gctcgtcagg cgcatccggt acggcaaata agcgtccatc
    26221 atcccgtttg atatcgtgtg tatcctgatc gataagcata aactgcgcaa gggatggggg
    26281 ctgaccgtct ttgttctccc acgtcttaac gttgagcgtt tttgctatag ccgcaatatc
    26341 atctttccgg gcgctgtagt cgcagtcaac agatgtggtg aggcgctcat caggcaatct
    26401 gtcgccgtat tgtgcatgat aataggatat ccagtattga cagcctgacc gccaactgtg
    26461 ataacggcat gtttgaactg atcagcgttg cagatcagct gctgatttct ctcatagcag
    26521 tcttgaacag gcataaaaaa ccatcagcat atggtttcca cctaagttca ggatcgcaga
    26581 aagcgatagt atgaggaatt tgctactagc tgacttactg aagcggcttt tcacggcagg
    26641 tttgtaaccg gcacgaccac gcaaaacctg caccgctacg gcttcgtagc gttcatgctg
    26701 cttttgttta gcttgtacgg gagacataat tttgtacctg acggtagtta taaacaaata
    26761 agttgcagta actatacgtc acgaatctac gtcacgcaat agagggcact gttgcaaata
    26821 gtcggtggtg ataaacttat catccccttt tgctgatgga gctgcacatg aacccattca
    26881 aaggccggca ttttcagcgt gacatcattc tgtgggccgt acgctggtac tgcaaatacg
    26941 gcatcagtta ccgtgagctg caggagatgc tggctgaacg cggagtgaat gtcgatcact
    27001 ccacgattta ccgctgggtt cagcgttatg cgcctgaaat ggaaaaacgg ctgcgtggta
    27061 ctggcgtaac ccttccgatc tttgcccgtg gcacatggat gaaacctacg aaggtcaatg
    27121 gccgctgggc gtatctgtct aggccgtcga cagccggggc cgcactgtcg atttttatct
    27181 ctcctcccgt cgtaacagca aagctgcata ccggtttctg ggtaaaatcc tcaacaacgc
    27241 ttgaagaagt ggcagatccc gcggattcat caacacggat aaagcgcccg cctatggtcg
    27301 cgctttgttc tgctcaaacg cgaaggccgg tgccgtctga cgttgaacac cgacagatta
    27361 agtaccggaa caacgtgatt gaatgcgatc atggcaaact gaacggatgt caatcggcgc
    27421 cacgctggga tttaaatcca tgaagacggc tacgccacca tcaaaggatt gaggtgatgc
    27481 gtgcactacg caaaggccag gcctcagcat tttattatgg tgatcccctg ggcgaaatgc
    27541 gcctggtaag cagagttttt gaaatgtaag gcctttgaat aagacaaaac gctgcctcat
    27601 cgctaacttt gcaacagtgc caaaattttt ctgtggtcct tgagcgaacg gtacgggaac
    27661 tgaacgggga aagctgcctt tcgcttgagg aagcccctcc gacgaaacag caaattgtct
    27721 gcagccgcag ttttggcgtg aagatcacgg agtacgagtc actccgtcag gctatctgtc
    27781 agcacgcaga gcgggcctct gaaaaactgc gtaaagagca ccagtattgc cggcatattt
    27841 ccgttttcat caaaacgtct ccgttcgcca ttaaagagcc ttactacggc aacgtggcta
    27901 cggaaaaact gcttacaccc actcaggaca ccagggacat cattgcagcc gccacaacgg
    27961 ctctggagcg tatctggagg gatgggcacc ggtatgccaa agccggagtt atgctgaatg
    28021 acttcaccgg ctccggcgtt tcgcagctgc agctgtttga cgaacgcccg ccacgccctc
    28081 acagtgctga gctgatgagg gttctggacg ggatcaacaa ctcagggctg tgtaaagtat
    28141 ggtttgccgg tagaggaatt gcgccatcct ggcaaatgaa acgcgatatg ctctcccctg
    28201 cgtacaccac tcgctggaga gatatccccg ttgcgaggat cggttaaatt ttgcctttca
    28261 gagagagcca gcagtgctcg ccgcagccga acgacagggc gaagcccgcg agtgagcgag
    28321 gaagcaccag gggagctgaa gccttttaaa gcaccttacg cacttaagtt ctatagattc
    28381 cataatgagt tatccacata tcctttgagt agatccaata acttaccctt agttatccaa
    28441 atagatccaa actgatccct ttagcggcaa aacctttgtt tacgggcttc gtagcgattt
    28501 caggtgtgtc gtagtgggaa aaaggtgttc tgaagcggga aaaaggtgtg tcaaaacggg
    28561 gtaagggtgg gtagaatcgg gaagaaaggt gtgtcaaaac gggaaatagt taatatttag
    28621 gcacatatcg atcatatgct
//
