LOCUS       NZ_CP034419             5596 bp    DNA     circular CON 26-NOV-2023
DEFINITION  Klebsiella pneumoniae strain C789 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP034419
VERSION     NZ_CP034419.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN10537194
            Assembly: GCF_009684575.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5596)
  AUTHORS   Zhang,Y., Jin,L., Ouyang,P., Wang,Q., Wang,R., Wang,J., Gao,H.,
            Wang,X. and Wang,H.
  CONSRTM   China Carbapenem-Resistant Enterobacteriaceae (CRE) Network
  TITLE     Evolution of hypervirulence in carbapenem-resistant Klebsiella
            pneumoniae in China: a multicentre, molecular epidemiological
            analysis
  JOURNAL   J Antimicrob Chemother 75 (2), 327-336 (2020)
   PUBMED   31713615
REFERENCE   2  (bases 1 to 5596)
  AUTHORS   Zhang,Y., Jin,L., Ouyang,P., Wang,Q., Wang,R., Wang,J., Gao,H.,
            Wang,X. and Wang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2018) Department of Clinical Laboratory, Peking
            University People's Hospital, No. 11 Xizhimen South Street, Beijing
            100044, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Other Unicycler pipeline v. v0.4.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 125.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/26/2023 04:02:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,864
            CDSs (total)                      :: 5,742
            Genes (coding)                    :: 5,578
            CDSs (with protein)               :: 5,578
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 164
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 68 of 164
            Pseudo Genes (incomplete)         :: 106 of 164
            Pseudo Genes (internal stop)      :: 22 of 164
            Pseudo Genes (multiple problems)  :: 32 of 164
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034419.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5596
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="C789"
                     /isolation_source="blood specimen"
                     /db_xref="taxon:573"
                     /plasmid="unnamed2"
                     /geo_loc_name="China: Shandong"
                     /collection_date="2016-04-14"
     gene            join(5429..5596,1..342)
                     /locus_tag="EJJ25_RS30660"
     CDS             join(5429..5596,1..342)
                     /locus_tag="EJJ25_RS30660"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            349..561
                     /locus_tag="EJJ25_RS28680"
     CDS             349..561
                     /locus_tag="EJJ25_RS28680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            1228..1452
                     /locus_tag="EJJ25_RS28685"
                     /old_locus_tag="EJJ25_29985"
     CDS             1228..1452
                     /locus_tag="EJJ25_RS28685"
                     /old_locus_tag="EJJ25_29985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            1436..1702
                     /locus_tag="EJJ25_RS28690"
                     /old_locus_tag="EJJ25_29990"
     CDS             1436..1702
                     /locus_tag="EJJ25_RS28690"
                     /old_locus_tag="EJJ25_29990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(1772..2122)
                     /locus_tag="EJJ25_RS28695"
                     /old_locus_tag="EJJ25_29995"
     CDS             complement(1772..2122)
                     /locus_tag="EJJ25_RS28695"
                     /old_locus_tag="EJJ25_29995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197756.1"
                     /translation="MYWLIAFLAFIFPGRSFADGYTAYYRCNGTQEASLTVKDNKLSMV
                     VGLSKFNRQLDTYRFKEKGIEVVMQRAASDDNSEAIMSFIMPDVNNMTLLVKNNGYIIV
                     KTTCWLTKTDKQ"
                     /name="hypothetical protein"
     gene            complement(2188..2733)
                     /locus_tag="EJJ25_RS28700"
                     /old_locus_tag="EJJ25_30000"
     CDS             complement(2188..2733)
                     /locus_tag="EJJ25_RS28700"
                     /old_locus_tag="EJJ25_30000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            complement(2759..3085)
                     /locus_tag="EJJ25_RS28705"
                     /old_locus_tag="EJJ25_30005"
     CDS             complement(2759..3085)
                     /locus_tag="EJJ25_RS28705"
                     /old_locus_tag="EJJ25_30005"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     gene            complement(3443..3601)
                     /locus_tag="EJJ25_RS30860"
     CDS             complement(3443..3601)
                     /locus_tag="EJJ25_RS30860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     gene            4241..4417
                     /locus_tag="EJJ25_RS30320"
     CDS             4241..4417
                     /locus_tag="EJJ25_RS30320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     gene            4407..4751
                     /locus_tag="EJJ25_RS28710"
                     /old_locus_tag="EJJ25_30015"
     CDS             4407..4751
                     /locus_tag="EJJ25_RS28710"
                     /old_locus_tag="EJJ25_30015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062955149.1"
                     /translation="MAVKRTRFLGIRVTDGEYQQLLERCNGRQLAVWMRETCLDTRPAR
                     SLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRVQVVAALMAIDAELERLRHA
                     VLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            complement(4933..5178)
                     /locus_tag="EJJ25_RS30665"
     CDS             complement(4933..5178)
                     /locus_tag="EJJ25_RS30665"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032433971.1"
                     /translation="MQPQSPVHHGLPRIDARTVCPVVVRLETPAGQQFRVRYQKIQFQP
                     PLVPVFNPQHAVLVFIESGHQNPLEARHQLFTLAGR"
                     /name="hypothetical protein"
     Typing          4076..4155
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="90.361"
                     /coverage="97.0"
                     /evalue="1.1100000000000001e-21"
     Typing          complement(3493..3890)
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          4..677
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.556"
                     /coverage="99.0"
                     /evalue="1.48e-119"
     Typing          4742..5595
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 cagggtatga gcgcggccat gcagtcgaac cgcctgagcg tgatgcgtat ggtcgggcgg
       61 acatggctga ccatcacgat ggtgtcagga ctgctgttcg ccagcctgag cggggtgttg
      121 tggtatcagg ggagcttgat agcgtcaaat ctggccgaaa tcgaccggca gaacgcagcg
      181 ctgtcgaagc tgaacgcgaa gacctggggc gtgacgtacc tggaagacag caacggacgt
      241 tttctggtgc tgccgaaggg gacggccgta gacaggacgc agagctggac ggtcgggaac
      301 gggcggtcga agcagaacgc gctgagactg gtgaaggagt aagtgccgat gaccgagctg
      361 gaaaaacagt tgctgagcgc attagagcag ctacagcagg actactcgaa aaggctggac
      421 gagtgggaga gcgccttcgg ggaatggcgg aaaatgtcag ggcttatgca acgggagaac
      481 gcggcgctga gcgagcgcgt gacgcgcttg agtcagcagg tggaacgctt gagcgggcaa
      541 ctgcagcgtt tgagccggta gtgcagcgtc atgagatggc cgtggccgca gaacgggcgc
      601 acgagcaacg gcagcacgaa aaggaactga cggaagcgcg ttcccggcag cgaagctatg
      661 acggtccgtc gctgggctga aatgcaggaa aacagggttc tcatcgggca tttacgctga
      721 aaccggatgt cattcacctg gctgcatggc tatgcagcca ggtaaaattt atctgtcgcg
      781 aacggggcgg tttatcgggt ggtttgttgc cggttttacc tgactgccac cccgttcgcg
      841 gcgaacccgt ccggggcggt gcgggcaacg ggtgttatgt ttaatcagcg tgaacggcag
      901 atacaaaaaa gccccggagg gcttttaact actgacttat ttttttgaag atttgctggg
      961 tttcaatttg tcagtatttc ccggcgtttt tttattgtca cgctggcgtt tatcaggttc
     1021 ccctgttgaa tcggcaattc gtttcggacc cggcttaaga cccataatcg ttatcctttc
     1081 aatagttaag aggaaagccc tcaagctaga tatattgacc gcgttacgga ttatcaagag
     1141 gggctaacaa gattattttt tgttctttta ggttgattgt ggtactgttg atatacatgt
     1201 atagcaaatg gtgttcggga ggtttatatg cttgctatcc ggttatctga tgagattgag
     1261 tcccgtctgg actcgctggc gaagcaaacc ggcagaacaa agacgtttta tgcgcgggaa
     1321 gcaatactgg cgcatctgga agacctggag gattattatc tttcagcaga aactgctgca
     1381 cgcgttcgcc gtggtgatga agcagtgcat tcgtctgaag acgtgaggaa gtcacttggt
     1441 ctggacgatt aactattccg atcgggcgct caaatcgtta cgcaagatgg acaaacagaa
     1501 cgcacgacgg attgtggatt ttatgagttt acgcattgca gttgctgccg atcctcgcca
     1561 gtcagggaag ccgctcaaag gtgagctggg cgagttctgg cgctatcggg tgggagatta
     1621 tcgcgttctg tgtgagatcc gagatgacga gcttgttatc cttgccgcca cgattggaca
     1681 tcgccgcgaa gtttacgact gaagcccgct atgcgggctt ttttgatgcc gacaacaggt
     1741 attatggtaa atactcgact aactacgtgt tctactgttt gtcggtttta gttaaccagc
     1801 aggttgtctt aacgataatg tagccgttat ttttaactaa taaggtcata ttgttaacgt
     1861 caggcataat aaaagacatt atggcctcag agttatcatc agaagcagct ctctgcatta
     1921 ctacttcgat tcccttttct ttgaatctat aagtatccag ttgcctatta aacttagaaa
     1981 gacctacaac catacttagt ttgttatctt taacagtaag agatgcttcc tgagtaccat
     2041 tacatcggta gtaagcggtg taaccgtcag caaaagatcg accggggaat ataaatgcta
     2101 ggaacgcaat taaccaatac atagttgaga atcttggtat tacacatttc actatcctct
     2161 ctttcatttt tcgttcacca tactttgtta tctgattttt aatttttcta ttttataaac
     2221 caagtctcta ccaaaaaggc gaaaattatc ctcaaataat aataattgtt taagaacatc
     2281 catgaaagca gctgcttcac cctcagttat gggagctact ctatataaca tataacctga
     2341 gttaagggtt tcttttatac tttcttcaat gctcattata aatattagtg gattatcatt
     2401 tttcttcccc catgggtttc taattaatcc ttcgatgtac tcaggtcctt tgcgtcctat
     2461 tgcctgcgca atatttttta tttcatctgc gtgagggctt tgttgtacag ctttgtttat
     2521 gcctgcttga gtgattttca gagactctac accgtgtatg ttgtatgaga taaaatgtaa
     2581 taaattaaga tgcaatgcaa ttaatccatt tttgtttaca tctgagtatt tggataaaaa
     2641 acgtaatgaa gtgttaactc tcccttgaag cctaacaatt gggagtgctg ccttgtatat
     2701 ttccttctcc gttaaatacc gtttaaaaaa cataattctc cgcctccgta tagcgtgcct
     2761 attttatttc gtcgtaaaac ttagctctga aatattcctt tagaaccatc atgtcattaa
     2821 taattgaatc tatctcatcc attttttctt ggtattcttt taatggtgaa gggagcggta
     2881 actcaatatt tgaaaagtga ttggcgagat agggatcaag gtttctcatc cattcaggct
     2941 tttcgccaat gcgttcttca actgaaagtg aacctgataa tctctggtta ataagatcac
     3001 ttagactcat tttggtttta ttcgaaagcc gttgtaagga ttgctttaat cctatatcta
     3061 gcatgatatt tgttctttct ctcattaccc ccccttgcta ttgcgttttt tgttgcgcac
     3121 aaagctacca ttgcgcatta agaaacgcaa taaaaaagga gggagggagt ggtttgtaca
     3181 tgatgtgcag tgcgctgagg gcatcagtgg cgggtgtttt tccgtgggat ggatggagct
     3241 ccggggataa cagaactgac gatcatttaa aggatcttct tgagatcctt tttttctgcg
     3301 cgtaatctct tgcactgtaa acgaaaaaac cgcctgggga ggcggtttga tcgaaggtta
     3361 agtcagttgg ggaactgctt aaccgggtaa ctgggtatac gagaccgcag ataccaaaac
     3421 tgttctttca gtgtagccgc agttaggcac ccacttcaag acctctcaat atctctctcg
     3481 tatatatcca gttaccaatg gctgctgcca gtggcgtttt tgcgtgtccg tccgggttgg
     3541 actcaagatg atagttaccg gaaagggcgc agcagtcggg ctgaacgggg ggttcgtgca
     3601 tacagcccag cttggagcga acgacctaaa ccgagccgag ataccagcag cgtgagctat
     3661 gagaaagcgc cacgcttccc gaaagggaaa aaggcggaac aggtatccgg taaacggcag
     3721 ggtcggaaca ggagagcgca cgagggagcc gccggagaga aatcaccggc atctttaagt
     3781 cctgtcgggt ttcgtcctcc tctgacttga gcgtccattt ctgtgatgct cgtcagggga
     3841 ggcggagcct atggaaaaac ggcaacgccg catccttttc tccggccctt tctgatttga
     3901 gcgcctttgc tttatcccgt tatccgtgag tcggtcacgc ccgccgcagc cgaacggcag
     3961 gagcgcagct accgagtgag cgaggaggcg tcatttcatc tgtccgtgca tggtattgcg
     4021 gacgctcctg agccacatat cacacctgcc acatgaggca ctttcatgaa tcgtgctctc
     4081 atgccaacat agtaagccag tatacacagc gtaaacgctg tgactggttc agggctgcgc
     4141 cccgaaaccc gctaacacca ctgacgcgct ggcgcttgtc caacgccgga gcgacccgga
     4201 aaacttttcc gtgccgtccg gcgtttgcga aggagggata atgcagaagc cgaagaagaa
     4261 gccgctcgtc gtaaaaaaaa gatcctggca tccggcagtg atggcaaatc tgatgcgtca
     4321 ggcacaggag gaagattacc gccgggagca gatggcagag cttgagcgtt cagcccggtc
     4381 acattttgcg gatatcggag gagaggatgg cggttaagcg tacccgtttt ttaggtatcc
     4441 gggtgaccga tggggagtac cagcagctgc tggagcgctg caatggaagg caactggcgg
     4501 tgtggatgcg ggaaacctgt ctcgatacgc gcccggcgcg gtcgttgcgg ctgccgtcca
     4561 tcgatccggt tttgctgcgc cagcttgccg ggatggggaa caacctcaac cagatcgccc
     4621 ggaaaattaa cggcggccag tggtcaggcg ctgaccgggt tcaggtggtg gccgcgctga
     4681 tggccattga tgccgaactc gagcggctgc ggcatgccgt gctggaaaag ggggcagacg
     4741 atgatcgtta agtttcatcc gcgagggcga ggcggcggtg ccgggccggt ggattatctg
     4801 ctggggaaag accgccagcg cgacggggcc atcgtcctgc agggaaagcc ggaggaggtc
     4861 cgggagctta tcgacgcctc gccctacgcc aaaaagtaca cctccggcgt cctgtctttt
     4921 gctgaacagg atttaccgcc cggccagcgt gaaaagctga tggcgagctt cgagcgggtt
     4981 ctgatgcccg gactcgataa agaccagtac agcgtgctgt gggttgaaca ccgggacaag
     5041 gggcggctgg aactgaattt tctggtaccg aacacggaac tgctgaccgg caggcgtctc
     5101 cagccgtact acgaccgggc agaccgtccg cgcatcgatg cgtggcagac cgtggtgaac
     5161 gggcgactgg ggctgcacga cccgaacgca ccggagaacc ggcgcgcgct ggtgacgcca
     5221 tcttcgttac ccaaaacgaa gcaggaagcc gcagaggcta ttacgcgggg cttactggcc
     5281 ctcgcctcgt caggggagct taaaacgcgt caggacgtca ctgaggcgct ggaaagcgca
     5341 ggttttgagg tcgtgcgcac cacaaagagc agcatcagca ttgccgaccc ggacggaggg
     5401 cgaaacatcc gacttaaggg agccatctat gaacagtctt ttaacgctgg cgaaggactt
     5461 agagcagaaa tcgaaagcgc agcagcagag taccggcgaa atgctgaaag ccgcattcag
     5521 cgagcacgag aagtctgtca gagcggaact gagcgaaagc gggaagagaa tcagcgccgc
     5581 catccgcgcc cacgag
//
