LOCUS       NZ_CP033781            30843 bp    DNA     circular CON 17-JUL-2023
DEFINITION  Staphylococcus epidermidis strain FDAARGOS_529 plasmid unnamed1,
            complete sequence.
ACCESSION   NZ_CP033781
VERSION     NZ_CP033781.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN10163224
            Assembly: GCF_003812425.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis
  ORGANISM  Staphylococcus epidermidis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 30843)
  AUTHORS   Campos,J., Goldberg,B., Tallon,L., Sadzewicz,L., Zhao,X.,
            Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S., Geyer,C.,
            Nandy,P., Yan,Y. and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 30843)
  AUTHORS   Campos,J., Goldberg,B., Tallon,L., Sadzewicz,L., Zhao,X.,
            Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S., Geyer,C.,
            Nandy,P., Yan,Y. and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2018) Center for Devices and Radiological Health,
            US Food and Drug Administration, 10903 New Hampshire Avenue, Silver
            Spring, MD 20993-0002, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SMRT v. 2.3.0, HGAP v. 3.0, SPAdes v. 3.6.0
            Genome Coverage                   :: 2140.01391846154x
            Sequencing Technology             :: PacBio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/17/2023 01:40:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,476
            CDSs (total)                      :: 2,392
            Genes (coding)                    :: 2,314
            CDSs (with protein)               :: 2,314
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 43 of 78
            Pseudo Genes (incomplete)         :: 48 of 78
            Pseudo Genes (internal stop)      :: 33 of 78
            Pseudo Genes (multiple problems)  :: 32 of 78
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033781.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..30843
                     /organism="Staphylococcus epidermidis"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_529"
                     /isolation_source="CVP line blood"
                     /host="Homo sapiens"
                     /culture_collection="FDA:FDAARGOS_529"
                     /db_xref="taxon:1282"
                     /plasmid="unnamed1"
                     /collection_date="2016-03-24"
                     /collected_by="Children's National Hospital"
     gene            complement(join(30477..30843,1..290))
                     /locus_tag="EGX64_RS00005"
                     /old_locus_tag="EGX64_00005"
     CDS             complement(join(30477..30843,1..290))
                     /locus_tag="EGX64_RS00005"
                     /old_locus_tag="EGX64_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001831384.1"
                     /translation="MNHNHEYHSNKPEIKANVVYRDGNIEITLEDEFNNAPLLDTMHEK
                     EMHFVLVSNDMEKYYHLHPQKKHEGLFIINQQLEPGTYQAFVDVTPKNHVYSVHPIELQ
                     IGDKITSTTSLNSDKNWVKVNKGVHVTLNSISAKEDEHVPLTFNTELTPQPYLGALGHV
                     IIFDEQLTDYIHVHPESPDSTTFYAHFPKKGMYKIWAEFKFNDEVHRFTYNIKVA"
                     /name="hypothetical protein"
     gene            complement(354..563)
                     /gene="copZ"
                     /locus_tag="EGX64_RS00010"
                     /old_locus_tag="EGX64_00010"
     CDS             complement(354..563)
                     /gene="copZ"
                     /locus_tag="EGX64_RS00010"
                     /old_locus_tag="EGX64_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831373.1"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="WP_001831373.1"
                     /translation="MTNEVINVEGMSCDHCKHSIEKALNGLDGVTSSEVSLANGNVEVE
                     FDENQVAFNDFKEAIEDQGYDVIK"
                     /name="copZ"
     gene            complement(597..2984)
                     /locus_tag="EGX64_RS00015"
                     /old_locus_tag="EGX64_00015"
     CDS             complement(597..2984)
                     /locus_tag="EGX64_RS00015"
                     /old_locus_tag="EGX64_00015"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485948.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0019829 - ATPase-coupled monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_001832797.1"
                     /translation="MSENIKKTSLGITGMTCAACSNKVEKNLNKLDEVNANVNPSTEKA
                     TIEYNPNVTSLEDIANTIQKTGYGVLTEKVDLDVMGMTCAACSNKIEKVLNRISGVNKA
                     TVNLTTESATVEYNPDMTSVDEFQQRIKNLGYEAQPKKEASEKSSQKEKQLKRQLIKLV
                     VSAVLAAPLLMTMFVHLFGIQIPHIFMNPWFQFVLATPVQFVIGWQFYVGAYKNLRNGS
                     ANMDVLVALGTSAAFFYSIYESIKWLINTNYEPHLYFETSAVLITLILFGKYLEARAKT
                     QTTNALSKLLNLQAKEARILRNGEETMVPLSEVKEGDYLVIKPGEKIPVDGKIIKGMTS
                     IDESMLTGESIPVEKMQNDNVIGSTMNKNGAITVEATKVGKDTALASIVKVVEEAQGSK
                     APIQRLADIISGYFVPIVVGIAIFTFIIWISLVQPGQFEPALVAAIAVLVIACPCALGL
                     ATPTSIMVGTGKAAENGILFKGGEHIEGTHAINTVVLDKTGTITNGTPEVTDFSGDDQT
                     LQLLASAEKGSEHPLAEAIVSYAKEKSLEFLEVDHFEAIPGRGINATIDGKELFVGNRK
                     LMSEKGIQTNEAETNLAQFEKEGKTAMLISVDNELRGVVAVADTVKDTAQQAIQKLHEL
                     GIEVAMLTGDNKRTAQAIAKQVGIDTIIAEVLPEEKASKVAEIQSEGKKVAMVGDGVND
                     APALVKADIGIAIGTGTEVAIEAADITILGGDLLLIPKAIKASKSTIRNIRQNLFWAFG
                     YNVAGIPIAAIGLLAPWVAGAAMALSSVSVVTNALRLKRMKL"
                     /name="heavy metal translocating P-type ATPase"
     gene            complement(2999..3274)
                     /locus_tag="EGX64_RS00020"
                     /old_locus_tag="EGX64_00020"
     CDS             complement(2999..3274)
                     /locus_tag="EGX64_RS00020"
                     /old_locus_tag="EGX64_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831396.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0046872 - metal ion binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="WP_001831396.1"
                     /translation="MNTTTVKNNDALLNRLKRLEGQMRGLQSMIAEDRYCIDVLVQITA
                     IQSALKQVGFIVTEDHISNCVSEGIKNGNGEESIKELMVVLKQFSK"
                     /name="metal-sensing transcriptional repressor"
     gene            3449..3724
                     /locus_tag="EGX64_RS00025"
                     /old_locus_tag="EGX64_00025"
     CDS             3449..3724
                     /locus_tag="EGX64_RS00025"
                     /old_locus_tag="EGX64_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489264.1"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
                     /protein_id="WP_001831374.1"
                     /translation="MDKNIQLELYTRPTCSDCQESKRYLNSQEISYSHKDVSQNLDLEE
                     EMKKISGNRIVPLFVFYKKIFWGKKKLFKYYVGFENNKKDILNILE"
                     /name="glutaredoxin family protein"
     gene            complement(3765..4706)
                     /locus_tag="EGX64_RS00030"
                     /old_locus_tag="EGX64_00030"
     CDS             complement(3765..4706)
                     /locus_tag="EGX64_RS00030"
                     /old_locus_tag="EGX64_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449936.1"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_001831389.1"
                     /translation="MENDHNHNHTHGANKKTLLISFIIITSYMIVEGLGGFFTNSLALI
                     SDAGHMLSDSISLGIALIAFTLGAKQANTNKTFGYKRFEILAAVLNGITLMLIAIYIFY
                     EAIERFKNPPEVASTGMLIIALVGLFINIIVAWIMLRGSDVEENLNMRGAYLHVISDML
                     GSIGAVIAALLIIFFRWGWADPLASVIVAILVLRSGFYVTKSSLHVLMEGAPSNINTKD
                     IIKTIKKFKEVKNIHDFHVWSVTSGLNALSCHIVVEDTMTITENEFLLKRIEHELNHQN
                     IQHVTIQTETSNNNHSEKLFCIVKEEDSQHHH"
                     /name="cation diffusion facilitator family transporter"
     gene            complement(5069..5554)
                     /locus_tag="EGX64_RS00035"
                     /old_locus_tag="EGX64_00035"
     CDS             complement(5069..5554)
                     /locus_tag="EGX64_RS00035"
                     /old_locus_tag="EGX64_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002487969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_002487969.1"
                     /translation="MKTVKEVSELLDVSKQTIHYHLKSLPSNLKVNKVGNKSLIDDNTI
                     DYLKTILNKKTTKESTKFDEKSTNKTESLNNQYSSYIDKYIEHLESEIRQKNRQIDDLT
                     IALKQEQSLNLNSQNILSNTKKIETDNIDSKEDIITPKASKKNEQKQSIFSKLFKKK"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(5573..>5839)
                     /locus_tag="EGX64_RS00040"
                     /old_locus_tag="EGX64_00040"
                     /pseudo=""
     CDS             complement(5573..>5839)
                     /locus_tag="EGX64_RS00040"
                     /old_locus_tag="EGX64_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497232.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepB"
                     /name="replication protein RepB"
     gene            complement(5899..6573)
                     /locus_tag="EGX64_RS00045"
                     /old_locus_tag="EGX64_00045"
     CDS             complement(5899..6573)
                     /locus_tag="EGX64_RS00045"
                     /old_locus_tag="EGX64_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            6665..7057
                     /locus_tag="EGX64_RS00050"
                     /old_locus_tag="EGX64_00050"
     CDS             6665..7057
                     /locus_tag="EGX64_RS00050"
                     /old_locus_tag="EGX64_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000393259.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYT
                     LLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACH
                     VYEKLGGKNDYKDEIVYVYDYEKGDK"
                     /name="GNAT family N-acetyltransferase"
     gene            7058..8497
                     /gene="aph(2'')-Ia"
                     /locus_tag="EGX64_RS00055"
                     /old_locus_tag="EGX64_00055"
     CDS             7058..8497
                     /gene="aph(2'')-Ia"
                     /locus_tag="EGX64_RS00055"
                     /old_locus_tag="EGX64_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="WP_001028144.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
                     /name="aph(2'')-Ia"
     gene            complement(8627..9798)
                     /locus_tag="EGX64_RS00060"
                     /old_locus_tag="EGX64_00060"
                     /pseudo=""
     CDS             complement(8627..9798)
                     /locus_tag="EGX64_RS00060"
                     /old_locus_tag="EGX64_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /name="IS256-like element IS256 family transposase"
     gene            9861..10301
                     /locus_tag="EGX64_RS00065"
                     /old_locus_tag="EGX64_00065"
     CDS             9861..10301
                     /locus_tag="EGX64_RS00065"
                     /old_locus_tag="EGX64_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831392.1"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA];
                     GO:0004521 - RNA endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III toxin-antitoxin system ToxN/AbiQ family
                     toxin"
                     /protein_id="WP_123985655.1"
                     /translation="MAFLLLHNYTDFIRPYLGVVLSINDLNYFVPLSSPKENKKLNNQL
                     SIKLFEVNNIQNRLGYLLFLNMIPVPDKYLSKIDMQYIKEQDLEYYNLLTNQLIFIRQE
                     NQRIVNKAQKVYKNAVIKKVSFFESMCVDYLALERYVKDLKQ"
                     /name="type III toxin-antitoxin system ToxN/AbiQ family
                     toxin"
     gene            10591..11199
                     /locus_tag="EGX64_RS00070"
                     /old_locus_tag="EGX64_00070"
     CDS             10591..11199
                     /locus_tag="EGX64_RS00070"
                     /old_locus_tag="EGX64_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_031770363.1"
                     /translation="MIIGYARVSSTDQNLERQIDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSTNAKDPQKRI
                     IYHRVVEMLKEGTAISKIAKEVNITRQTVYRIKHDNDLV"
                     /name="recombinase family protein"
     gene            11408..12082
                     /locus_tag="EGX64_RS00075"
                     /old_locus_tag="EGX64_00075"
     CDS             11408..12082
                     /locus_tag="EGX64_RS00075"
                     /old_locus_tag="EGX64_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_046044638.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLNIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQALSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTSKNTLKGIECIYALYKKNRISLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            12150..12305
                     /locus_tag="EGX64_RS00080"
                     /old_locus_tag="EGX64_00080"
     CDS             12150..12305
                     /locus_tag="EGX64_RS00080"
                     /old_locus_tag="EGX64_00080"
                     /inference="COORDINATES: protein motif:HMM:NF024573.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="WP_235318316.1"
                     /translation="MYAFEESETSLHPNHQLMLIESFLSLSSNSNNINYPYAKFSIYAT
                     IRKFDI"
                     /name="ATP-binding protein"
     gene            12478..12768
                     /locus_tag="EGX64_RS00085"
                     /old_locus_tag="EGX64_00085"
     CDS             12478..12768
                     /locus_tag="EGX64_RS00085"
                     /old_locus_tag="EGX64_00085"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="TOPRIM nucleotidyl transferase/hydrolase
                     domain-containing protein"
                     /protein_id="WP_031770370.1"
                     /translation="MKVMLYHIHLEEKGFALLSTGGSGNLKSWINLKVIEQFNIPWCIL
                     QDSDIGPNDENANREKKQELESKGIKMYLTKKEKLKNIKVPMVTLGMNLQK"
                     /name="TOPRIM nucleotidyl transferase/hydrolase
                     domain-containing protein"
     gene            complement(12948..13103)
                     /locus_tag="EGX64_RS12775"
     CDS             complement(12948..13103)
                     /locus_tag="EGX64_RS12775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002485021.1"
                     /translation="MGKTPQVKPGLPNPWTTAAQIVTAASCKHHTKYSCETSPAETKHP
                     KAPGSN"
                     /name="hypothetical protein"
     gene            complement(13180..14898)
                     /locus_tag="EGX64_RS00090"
                     /old_locus_tag="EGX64_00090"
     CDS             complement(13180..14898)
                     /locus_tag="EGX64_RS00090"
                     /old_locus_tag="EGX64_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447382.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_046044639.1"
                     /translation="MKQKNPVLHLVNEIEIPKWLLFFSVLLSVIGSIFQLIVPLFTQNI
                     VDNFSEVIKNKYYIIVFVFIFLLSSILNGLSIYLLTKLGENIIYSLTNKVWNHILRLKT
                     SFFDKNSNGELLSRIIDDTKSINSFITEIIPSFFPSIIVLFGSIFFLFMLDWETALIAL
                     ISIPMYVILIIPISNVMQKLSYKTQLETAKVSGVIAHVLSKIKLVKLSNSINKEFRQTN
                     SYLRNIYYLGVKEGVINSIVVPLSTLIMLVSMGGVLGFGGYRVASGAISPGTLIALIFY
                     MTQLTDPIEKISSLFTGYKKTIGASQRLSEILSEEKENLQNNNLNILNSVDLSFNNVSF
                     SYDESNHVFTNLSFTIPKNKITAIVGPSGSGKTTILNLISRLYEIQSGSIKYGTNSIYD
                     YSLINWRKNLGYVMQNSGVLNRTVKSNITYSLQETPCIEDIIYYSKLASTHDFIMKLPN
                     DYNTLIGEKGINLSGGEKQRLDIARNFIKTPGILLLDEATSNLDSESEHKIQESIKNVS
                     NDRTTIIVAHRLSTVLKADKIIFIDNGEITGMGTHAELLSRHSKYKNMIELQQLK"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(14918..15358)
                     /locus_tag="EGX64_RS00095"
                     /old_locus_tag="EGX64_00095"
     CDS             complement(14918..15358)
                     /locus_tag="EGX64_RS00095"
                     /old_locus_tag="EGX64_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_031770330.1"
                     /translation="MVYIIALLLFVLIISIIFFYNNINRKILDLQGIPISLPFPYKNFN
                     LTESKNYIFCLSTQCPHCAKIIDELLSLNDHLNNVYVIFIDDEVAVDNYFNTKGSFNFK
                     IIKDINWEELFISQTPFMYVVNEKNIITEKGILKNTKNLEIY"
                     /name="hypothetical protein"
     gene            15997..16311
                     /locus_tag="EGX64_RS00105"
                     /old_locus_tag="EGX64_00105"
     CDS             15997..16311
                     /locus_tag="EGX64_RS00105"
                     /old_locus_tag="EGX64_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_031770333.1"
                     /translation="MFEKMFKISSLLFLINMIFVAIKDIVLGGETTRAGNNLLVIITII
                     FTISMLITTFYYIKNRKSDSSKNYKGLYYTVLIFMPIVWILVGYYVFSPLPELLSHTNT
                     "
                     /name="hypothetical protein"
     gene            complement(17416..18354)
                     /locus_tag="EGX64_RS00115"
                     /old_locus_tag="EGX64_00115"
     CDS             complement(17416..18354)
                     /locus_tag="EGX64_RS00115"
                     /old_locus_tag="EGX64_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001132443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_046044640.1"
                     /translation="MPNFEKYNLSQVKTERFYQLPKYLFEDTYFKKMSAEAKIMYALLK
                     DRFELSIQNEWVDKNNNIYFIFSNKHLCEYLGYAEQKIIKLKKELINFNLLTQERVGLN
                     KPNRLYLLKPNYDMEVSHTKELPNSQFQNNEFGSSRTVNLSGQELPNSQSNDTDLNDTD
                     NIETDNNDTYDMNDIYNNSTSHNHSDHTNHQQIEFNNDALKFQVLEELPQQLQDYLSKF
                     EIREIRIIKSVLLKGKKSFNNAHYTYYRLEDVEFEIVNVLKRFKAMLLQKNETVETMQG
                     YLMQSIKAELEETHALYMRRQNMPIYNIFNE"
                     /name="replication initiator protein A"
     gene            18799..19569
                     /locus_tag="EGX64_RS00120"
                     /old_locus_tag="EGX64_00120"
     CDS             18799..19569
                     /locus_tag="EGX64_RS00120"
                     /old_locus_tag="EGX64_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_046044643.1"
                     /translation="MKTIKMVADELNVTKQTIVNNAKSLNISFEKENGINYINDNDCLK
                     IIEKITKKESTTQNKKSIKKERFDENTAEVEKYIYNNSNSFETLKTKANELEKQIEIFE
                     TRAKNDEKYIENLTKQLDQQNSNVNTLNKLLENQQILALESNKKIQKLENQLEEERQLN
                     YSFDTATNDRQSINPQEATFTEEPQNINQQQKKSQPIEAEVNHKDITEEKKDDSENEDV
                     LAKDDKPSEEIENGPEDRKEETSKKGFWRRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            19978..20077
                     /locus_tag="EGX64_RS12955"
                     /pseudo=""
     CDS             19978..20077
                     /locus_tag="EGX64_RS12955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500868.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(20281..21049)
                     /locus_tag="EGX64_RS00125"
                     /old_locus_tag="EGX64_00125"
                     /pseudo=""
     CDS             complement(20281..21049)
                     /locus_tag="EGX64_RS00125"
                     /old_locus_tag="EGX64_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117494.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            complement(21387..21827)
                     /locus_tag="EGX64_RS00130"
                     /old_locus_tag="EGX64_00130"
     CDS             complement(21387..21827)
                     /locus_tag="EGX64_RS00130"
                     /old_locus_tag="EGX64_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002476160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1307 domain-containing protein"
                     /protein_id="WP_235318315.1"
                     /translation="MVASIVILITLSACGNKKTKTFVGKKDNVKVEVTYTYKGDRIIKQ
                     KSVNTLKYSDFGISDDASKKLVKESIERQSEKIQDVKGVKESIKENDEGFVETIDVDFE
                     KADIDTLKSKGIVNIAGNTGTSISMKKTEKKMKENGFKEKED"
                     /name="DUF1307 domain-containing protein"
     gene            22996..23121
                     /locus_tag="EGX64_RS00140"
                     /old_locus_tag="EGX64_00140"
     CDS             22996..23121
                     /locus_tag="EGX64_RS00140"
                     /old_locus_tag="EGX64_00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="WP_070845701.1"
                     /translation="MTVYFYIWIKKEYLTSELFDLTESERQEINHQMIDEIEEEK"
                     /name="Rep protein"
     gene            23866..24630
                     /locus_tag="EGX64_RS00145"
                     /old_locus_tag="EGX64_00145"
     CDS             23866..24630
                     /locus_tag="EGX64_RS00145"
                     /old_locus_tag="EGX64_00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012818097.1"
                     /translation="MVSIIIHSIKILFRFMDFEKKSDYYFMLFINSIIVGGIFSIPVCL
                     DYLLLIKLPNELLSVFISIITFGLLLFFFASAILLIKEMMNFFIAFIDKKNRLFVKRTF
                     NRKYYENTMKLDSEDDIKRQLYENDISYPLRRLYKGIHYKYYNQDGEKLEEIALMFNKL
                     FYKRLICSKEHVKKKILWLLMTLLTTIVTTIYLLIKHFTNFQSFYMPIIILTIHNIYYF
                     LSVGIFSMVIGTIYKENLKSKLLILRFLKKGI"
                     /name="hypothetical protein"
     gene            complement(25035..>25148)
                     /locus_tag="EGX64_RS00155"
                     /old_locus_tag="EGX64_00155"
                     /pseudo=""
     CDS             complement(25035..>25148)
                     /locus_tag="EGX64_RS00155"
                     /old_locus_tag="EGX64_00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(25403..25588)
                     /locus_tag="EGX64_RS00165"
                     /old_locus_tag="EGX64_00165"
     CDS             complement(25403..25588)
                     /locus_tag="EGX64_RS00165"
                     /old_locus_tag="EGX64_00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020367458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_020367458.1"
                     /translation="MPKKTKLGNSLSFNYFLLLVGVLTFLGYYFLGDSNIMISWLLAMC
                     PITVGIANIGRIKNEK"
                     /name="hypothetical protein"
     gene            complement(26182..>26444)
                     /locus_tag="EGX64_RS13080"
                     /old_locus_tag="EGX64_00170"
                     /pseudo=""
     CDS             complement(26182..>26444)
                     /locus_tag="EGX64_RS13080"
                     /old_locus_tag="EGX64_00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            27691..27792
                     /locus_tag="EGX64_RS00180"
                     /old_locus_tag="EGX64_00180"
     CDS             27691..27792
                     /locus_tag="EGX64_RS00180"
                     /old_locus_tag="EGX64_00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_002497230.1"
                     /translation="MLDNFVHIMTTAASGCIVALFAHWLRNRNDKKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(27918..28808)
                     /locus_tag="EGX64_RS00185"
                     /old_locus_tag="EGX64_00185"
     CDS             complement(27918..28808)
                     /locus_tag="EGX64_RS00185"
                     /old_locus_tag="EGX64_00185"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: protein motif:HMM:NF012307.2"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase family protein"
                     /protein_id="WP_157768297.1"
                     /translation="MKQLKTYPIHQCAFYKCKSKKKLARLLKTDLNNLNRLSKSIEQEY
                     YTFNNKRQITAPKKELKVIQKRVLNLLNKIEKPDWVISSTKEKSYLDNAHYHIGAQYVC
                     TTDIRSFYNNCSRDRVYQFFAKKLLTSPDVAKLLSDITTLNYIPTGSPSSQILAYFAYE
                     EMFINMFNVSQEFNCKMTLYVDDLTFSKGNSFNYQKLINYIDIEARKFDHSLKYKKTNY
                     KSVKKGAKITGVILKNHELKIPNNLRMSILKDFEDIKNNQERKHQVISLKGKINAARLI
                     EPNHFNGTNSYVKKL"
                     /name="reverse transcriptase family protein"
     gene            complement(28810..29109)
                     /locus_tag="EGX64_RS00190"
                     /old_locus_tag="EGX64_00190"
     CDS             complement(28810..29109)
                     /locus_tag="EGX64_RS00190"
                     /old_locus_tag="EGX64_00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337516.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_046309805.1"
                     /translation="MKIGEVLKKLRLLYSVSAKDLAHDIGISPSYLSEIENSKKTPSLE
                     LLNKYSQVFEIKVSTIMLMAEDYSENRRKSKPEMFIQKRLIKILNKHTDELEEK"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(29757..30284)
                     /locus_tag="EGX64_RS00195"
                     /old_locus_tag="EGX64_00195"
     CDS             complement(29757..30284)
                     /locus_tag="EGX64_RS00195"
                     /old_locus_tag="EGX64_00195"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="WP_001831394.1"
                     /translation="MIKFEYFEEKDFDLLINWINSPELLVKWAGTDFNYPLDEEQLKEY
                     IKDTNKENSSKIIYKVIIEENNSKKIIGHIALNNIDFKNCSATLSKVLVGDPQMRGQGL
                     GPKIIKKLLKKAFEDLGLHRIELGVFAFNKSAIKSYKKIGFIKEGEKRDFRKLNGEYYN
                     LWQMSMLESEWS"
                     /name="GNAT family protein"
     ARG             7059..8494
                     /name="aac(6')-Ie/aph(2'')-Ia"
                     /gene="aac(6')-Ie/aph(2'')-Ia"
                     /gene_name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             7059..8497
                     /name="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene_name="aminoglycoside bifunctional resistance protein"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(17417..18354)
                     /name="rep_cluster_1215"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.291"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gaatacacat ggttttttgg tgtaacatca acaaaagcct ggtaagttcc tggctctaat
       61 tgttggttaa ttataaataa accttcatgc tttttttgag ggtgtaggtg gtaatatttc
      121 tccatgtcat tagatactaa aacgaaatgc atttcttttt catgcatagt atctaataat
      181 ggggcattat taaattcatc ttctaacgta atttctatat taccatctct atatacaaca
      241 tttgctttaa tttcgggttt gtttgaatga tattcatgat tatgattcat atttttatcc
      301 tccttaattt ttaataaggg catatcatta aacgatatgc ccaactattt aaattattta
      361 attacatcgt aaccttgatc ttcaatagct tctttaaagt cgttgaaagc tacttgattt
      421 tcatcaaatt caacttccac attcccattc gccaagctta cttctgaaga tgttacacca
      481 tctaatccat ttaatgcttt ttcaattgaa tgcttgcaat ggtcacagct cataccttct
      541 acattaataa cttcgttagt caatgttgtc acctcctttc aagaaatata agattcttat
      601 aatttcatac gttttagacg taaagcgttt gtgacaacac ttacagaact taaagccatt
      661 gctgctcccg caacccaagg tgctagcaga ccaattgctg ctatagggat acctgcaaca
      721 ttgtaaccaa acgcccaaaa tagattttgg cgaatattac gaattgtaga tttacttgct
      781 tttattgctt ttggaattaa taaaaggtct cctcctaaaa tagttatatc agcagcttcg
      841 attgcaactt ctgtacctgt accaatggca ataccaatat ctgctttaac tagtgctgga
      901 gcatcattga caccatctcc aaccatagct acttttttac cttcagattg aatttctgct
      961 actttagaag ctttttcttc tggtaaaacc tctgcaataa tcgtgtctat accaacttgt
     1021 tttgctattg cttgtgcggt acgtttgtta tcaccagtta acatagcaac ttcaatacct
     1081 aattcatgaa gtttttgaat agcttgttgg gcagtatctt taactgtatc agctacagcg
     1141 acaacccctc tcaattcgtt atctacgctt ataagcattg cagtttttcc ttctttttca
     1201 aattgagcga gatttgtttc agcttcatta gtttggattc ctttttcact cattagtttt
     1261 cgatttccga caaaaagttc tttaccatca attgttgcat ttataccgcg ccctggtata
     1321 gcttcaaaat ggtctacttc taaaaattct aatgattttt ctttagcata acttacgata
     1381 gcttcagcta gtgggtgttc agaacctttt tctgcactag ctaacaattg taatgtttga
     1441 tcatctccac taaaatcagt gacttcaggt gtgccatttg ttatagtgcc agttttatct
     1501 aaaacaactg tattaatagc gtgtgtacct tcaatgtgtt ctccaccttt aaatagaatg
     1561 ccattttcag cagcttttcc ggtacccacc attatagaag taggcgtagc taagcctaac
     1621 gcacaaggac aagcgataac taatactgct attgcagcaa ctaaggctgg ttcaaattgt
     1681 cccggctgaa ctaatgaaat ccatataata aatgtgaaaa tcgcgatacc tacaacgata
     1741 ggtacaaaat atccagaaat aatatctgct agtctttgta ttggcgcttt agaaccttgc
     1801 gcttcttcga caactttaac aatggaggca agagctgtat ctttaccaac ttttgttgct
     1861 tcaacagtaa ttgctccatt tttattcatt gttgatccta taacattatc attttgcatt
     1921 ttttcaacag gaatagattc acctgtcaac attgactcgt caattgaagt cataccttta
     1981 attattttgc catctactgg tattttttct cctggtttga taactaaata gtctccttct
     2041 tttacctcac ttaaaggaac catagtctct tcaccgttgc gtaatatacg tgcttcttta
     2101 gcttgtaaat tcaacaattt acttaacgca tttgttgttt gtgttttagc acgtgcttct
     2161 aaatactttc cgaaaagaat taaagtaatt aatacagcac ttgtttcaaa atataggtgt
     2221 ggctcataat ttgtattaat taaccactta atcgattcat aaatactata aaagaaggct
     2281 gcgcttgtac ctaaagcgac aagaacatcc atatttgctg acccattacg aaggttttta
     2341 taagcgccta cataaaattg ccaaccaata acaaattgaa caggcgttgc taatacaaat
     2401 tggaaccacg ggttcataaa tatatgtggt atttgaatac caaataaatg aacgaacatt
     2461 gtcattaaca atggagctgc taaaacagct gaaacaacta atttaattaa ctgtcgtttt
     2521 aattgttttt ctttttggga acttttttct gatgcttctt ttttaggttg tgcctcatac
     2581 cctaggtttt taatacgttg ttgaaattca tctacagacg tcatatcagg gttgtattct
     2641 acagtagcac tttctgtggt taaattaact gtagccttat ttacacctga gattcgattt
     2701 aaaacttttt cgattttatt cgaacaagct gcacacgtca ttcccattac atcgagatcc
     2761 actttttcgg ttaaaactcc ataacctgtt ttttgaattg tatttgcaat atcttctaat
     2821 gatgtaacat tggggttata ttcaattgta gctttctctg tagaaggatt tacattagcg
     2881 ttaacttcat ctaatttatt tagatttttt tctactttat tcgagcaagc tgcacatgtc
     2941 atgcctgtga tacctaatga ggttttttta atattttcac tcaattattt ctttcctcct
     3001 attttgaaaa ttgttttaat acaaccatca attctttgat actttcttct ccgttgccat
     3061 ttttaatacc ttcacttaca caattagata tatggtcttc agttactata aaacccactt
     3121 gttttagggc tgattgtatt gctgttattt gtactagtac atctatacaa tatctatctt
     3181 ctgctatcat tgattgtaaa ccgcgcattt gtccttctaa tcttttgagt ctattgagca
     3241 atgcgtcatt gtttttaaca gtagtagtgt tcaatttcac ccctcctcat ataccctaac
     3301 ggggtatctc ttgttggaat ctatattata cccctagtag gtataagtca atacaaaagt
     3361 ttcatataaa aaattaatat ttatagtttg ttttaagagg tacacttgta taaaatgtat
     3421 gctaaaactt atattaggag agatatattt ggataaaaat atacaacttg agctttacac
     3481 aagacctaca tgctctgatt gccaagaatc aaaaaggtat ttaaactctc aagagattag
     3541 ttatagtcat aaagatgtaa gtcaaaattt ggacttagaa gaagaaatga aaaaaatatc
     3601 aggcaaccga attgttccct tatttgtttt ttataaaaaa attttttggg gtaaaaaaaa
     3661 gttgtttaaa tattacgtgg gatttgaaaa taacaaaaaa gatatattaa atatattgga
     3721 ataattaaat aaacagccat tattaaaaaa taatggctgt ttatttaatg atgatgttga
     3781 ctgtcttctt ctttcacgat acaaaacaat ttttcactat gattattgtt agaagtttca
     3841 gtctgtattg tgacatgttg aatattttga tgattgagtt catgttctat acgtttaagt
     3901 aaaaactcat tttcagtaat ggtcattgta tcttctacaa caatatgaca agataacgcg
     3961 tttaatccgc tagttactga ccaaacatga aagtcatgaa tatttttaac ttctttgaat
     4021 tttttaatag ttttaataat gtcttttgta tttatattgc ttggtgctcc ctccattaat
     4081 acatgaagac ttgattttgt tacataaaag ccgctacgta gtactaaaat tgctacaatc
     4141 acacttgcta aaggatccgc ccacccccat ctaaaaaata taatgagaag ggctgctata
     4201 actgcaccta tagatccaag catgtcgctt attacatgca aatatgctcc acgcatattt
     4261 aagttttctt ctacatcgct cccgcgcagc attatccaag ccacaataat attaataaac
     4321 aagcctacca aggcgataat taacatgcct gtagaagcta cctcaggggg gtttttaaat
     4381 ctctcaatag cttcataaaa aatatagata gctattaaca tcaaagtaat accattaagt
     4441 acagctgcta gtatttcaaa ccttttgtag ccaaaagttt tatttgtatt agcttgcttc
     4501 gctcctaaag taaatgcaat taaagcaata cctaaagaaa tagaatcact taacatatga
     4561 ccagcatctg aaattaacgc aagactgtta gtaaagaaac cacctaaccc ttctacaatc
     4621 atgtaacttg taataataat aaaactaatt aataaagtct ttttgttcgc gccatgtgta
     4681 tgattatgat tgtgatcgtt ttccatttaa tccctcctct ttttaatgat gaaaaatatt
     4741 ttctataatt tgaatttttg tttttataac tatagagtta aaaaatataa aatttcaatt
     4801 aatgttttgt tactcgaaga aaatcatact aacttatgaa tatatgctca tatattcata
     4861 agttagtatg atttttatcc tttgtcaata tagaaatgct ttgtattttg tatattaaat
     4921 aaaaacccta ctttgctttg gacagtagtg ggatttttgc atatgataaa ccacacttca
     4981 cttgctaaat attaactata ttataattaa caagtgataa tttcttttta gagaaaataa
     5041 tgtattcacg cctttaggcg tgaatacatt attttttttt gaatagttta gaaaagatag
     5101 attgtttttg ttcatttttt tttgatgctt ttggagtaat gatatcttct tttgaatcta
     5161 tattatcagt ttctattttt ttggtattac ttaatatatt ttggctattt aaattcaaag
     5221 attgttcttg ttttaatgca attgttaaat cgtcaatttg tcgattcttt tgtcgaattt
     5281 ctgattctaa atgctctatg tatttatcga tataactgct atattggtta tttaatgatt
     5341 ctgttttgtt tgtcgatttt tcatcaaatt ttgtcgattc ttttgtcgtt tttttattta
     5401 aaattgtttt tagataatct attgtattat catctattaa tgatttgtta cctactttgt
     5461 ttaccttcaa atttgaaggt aaacttttta aatgataatg aattgtttgt ttagagacat
     5521 ctaaaagttc agaaacttcc tttacagttt tcatcaaata actgggtctc ctttactttt
     5581 tcattttttg taaaaacgct tgacgttctt cttctgtata cgcagatgtc ttagatgtgg
     5641 ttggttcata agtgttattt tttaaccatt gtggcgtcat ttcacggctt atatattgtt
     5701 ttggtttgcc tgtacttatc atattagatt gtcgtttcga atgaatacgt ttctcaggtt
     5761 caaaagaaaa ttctaaccat tcaatctttc gtcctttttt agctttaatt ttattaatat
     5821 tgagattttt aaataaaaag ggttctgttg caaagtaaaa aatatagcta atcactaata
     5881 tatcatgtca gtgttcgttt aacttgctag catgatgcta atttcgtggc atggggaaaa
     5941 tccgtagatc tgaagagacc tacggttctt tttatataga gcgtaaatac attcaatacc
     6001 ttttaaagta ttctttgccg tattgatact ttgatatctt gtctttctta ctttaatatg
     6061 acggtgatct tgctcaatga ggttattcag atatttcgat gtacaatgac agtcaggttt
     6121 aagtttaaaa gctttaatta ttttagccat tgctgccttc gttgaaggtg cctgatctgt
     6181 aactaccttt tgaggcttac caaattgttt aatgagacgt ttgataaacg catatgctga
     6241 atgattatct cgttgcttac gcaaccaaat atctaatgta tgtccctctg tatcaatggc
     6301 acgatataaa tagctccatt ttccttttat tttgatatac gtctcatcaa tacgccattt
     6361 gtaataagct tttttatgct ttttcttcca aatttgatat aaaattgggg catattcttg
     6421 aacccaacgg tagatcgttg aatgatgaac gtttacacca cgttctctta atatttcaga
     6481 tatatcacga tagctcaatg catatcttag atagtagcca acggctacag tgataacatc
     6541 cttgttaaat tgtttatatc tgaaatagtt catacagaag actccttttt gttaaaatta
     6601 tattataaat tcaactttgc aacagaaccg cattttacac aggagtctgg acttgactga
     6661 gtttatggaa gaagttttaa ttgatgataa tatggttttt gatattgata atttaaaagg
     6721 atttcttaat gataccagtt catttgggtt tatagctaaa gaaaataata aaattatagg
     6781 atttgcatat tgctatacac ttttaagacc tgatggaaaa acaatgtttt atttacactc
     6841 aataggaatg ttacctaact atcaagacaa aggttatggt tcaaaattat tatcttttat
     6901 taaggaatat tctaaagaga ttggttgttc tgaaatgttt ttaataactg ataaaggtaa
     6961 tcctagagct tgccatgtat atgaaaaatt aggtggtaaa aatgattata aagatgaaat
     7021 agtatatgta tatgattatg aaaaaggtga taaataaatg aatatagttg aaaatgaaat
     7081 atgtataaga actttaatag atgatgattt tcctttgatg ttaaaatggt taactgatga
     7141 aagagtatta gaattttatg gtggtagaga taaaaaatat acattagaat cattaaaaaa
     7201 acattataca gagccttggg aagatgaagt ttttagagta attattgaat ataacaatgt
     7261 tcctattgga tatggacaaa tatataaaat gtatgatgag ttatatactg attatcatta
     7321 tccaaaaact gatgagatag tctatggtat ggatcaattt ataggagagc caaattattg
     7381 gagtaaagga attggtacaa gatatattaa attgattttt gaatttttga aaaaagaaag
     7441 aaatgctaat gcagttattt tagaccctca taaaaataat ccaagagcaa taagggcata
     7501 ccaaaaatct ggttttagaa ttattgaaga tttgccagaa catgaattac acgagggcaa
     7561 aaaagaagat tgttatttaa tggaatatag atatgatgat aatgccacaa atgttaaggc
     7621 aatgaaatat ttaattgagc attactttga taatttcaaa gtagatagta ttgaaataat
     7681 cggtagtggt tatgatagtg tggcatattt agttaataat gaatacattt ttaaaacaaa
     7741 atttagtact aataagaaaa aaggttatgc aaaagaaaaa gcaatatata attttttaaa
     7801 tacaaattta gaaactaatg taaaaattcc taatattgaa tattcgtata ttagtgatga
     7861 attatctata ctaggttata aagaaattaa aggaactttt ttaacaccag aaatttattc
     7921 tactatgtca gaagaagaac aaaatttgtt aaaacgagat attgccagtt ttttaagaca
     7981 aatgcacggt ttagattata cagatattag tgaatgtact attgataata aacaaaatgt
     8041 attagaagag tatatattgt tgcgtgaaac tatttataat gatttaactg atatagaaaa
     8101 agattatata gaaagtttta tggaaagact aaatgcaaca acagtttttg agggtaaaaa
     8161 gtgtttatgc cataatgatt ttagttgtaa tcatctattg ttagatggca ataatagatt
     8221 aactggaata attgattttg gagattctgg aattatagat gaatattgtg attttatata
     8281 cttacttgaa gatagtgaag aagaaatagg aacaaatttt ggagaagata tattaagaat
     8341 gtatggaaat atagatattg agaaagcaaa agaatatcaa gatatagttg aagaatatta
     8401 tcctattgaa actattgttt atggaattaa aaatattaaa caggaattta tcgaaaatgg
     8461 tagaaaagaa atttataaaa ggacttataa agattgatta tataatatat gaaaagctat
     8521 tataaaagac attagtatta aatagtttaa aaaaatgaaa aataataaag gaagtgagtc
     8581 aagtccagac tcctgtgtaa aatgctatac aatgttttta ccatttctac ttatcaaaat
     8641 tgatgtattt tcttgaagaa taaatccatt catcatgtag gtccataaga acggctccaa
     8701 ttaagcgatt ggctgatgtt tgattgggga agatgcgaat aatcttttct cttctgcgta
     8761 cttcttgatt cagtcgttca attagattgg tactctttag tcgattgtgg gaatttcctt
     8821 gtacggtata ttgaaaggcg tcttcgaatc catcatccaa tgatgcgcaa gcttttgaat
     8881 attttggttg atcgatataa tcatgaatca atcgattttt agcctcacgc gctaagttaa
     8941 tatctgtgaa cttaaaaatt cctttaacag cttctctgaa agattttgaa ttttttttag
     9001 gaatggtggt aaagatattt cttaggaagt gaacttggca tctttgccaa cttacgttgg
     9061 tgaaggattt tctaatggca gagactaatc ctttgtgcgc atcagaaata acgagttccg
     9121 taccttgtaa accgcgttct tttaggtatt caaaaaatgt tgtccaggtc tcttcgcttt
     9181 cgccactttg aatcatgaag ccgataattt cacggtcgcc atctttggtt attccaatcg
     9241 ctatatgaca gctttttgag agtactcgat tttcttctcg tacttttata tagagtacat
     9301 cggtcattaa gtaaggataa tttttttctg ataataaacg attctgccac tcgttaacca
     9361 taggttctag ctgttctgtt aagctagaaa cgaaggactt agagacggat ttaccacaaa
     9421 gttcttccac aatttttgat actttacgag ttgaaacgcc tgatacatac atttccaaca
     9481 ttgaagccat gagggctttt tcgtttcgtt gataacgttc aaacactgtg ggtgaaaatg
     9541 gccatcacgt gttctgggta cttttaattc tagcgtgcct acacgtgtcg taaagctgcg
     9601 ctcataatag ccatttcgtt gactttgtcg gttttctgtt cgttcatatt cttttgcttg
     9661 aatatattct gttcgttgat tttccattag ttgattaaat accgttgtta aaatattttt
     9721 agaaacgtca tcctttacag aatattcaat aatgctttga atctcttcgc ttttcagtgt
     9781 aaaatgtact tgggtcatgt aaaagtcctc ctgggtatgt ttttgtcgtt aaaaacattg
     9841 taccgtaaaa ggactgttat atggcctttt tacttttaca caattatacg gactttatcc
     9901 gtccttattt aggagttgta ttatctatta atgatcttaa ttattttgtc cccttaagtt
     9961 cccctaaaga aaataaaaaa ctaaataatc aactatcaat aaaattgttt gaggttaata
    10021 atattcaaaa tagattagga tatctattat ttttaaatat gatacctgtt cctgataaat
    10081 atctttctaa aatagatatg caatacataa aggagcaaga tttagaatat tataacttat
    10141 taactaacca attaattttt attaggcaag aaaatcaaag aatcgtaaat aaagcccaaa
    10201 aagtatataa aaatgctgtg ataaaaaaag tttcattttt tgaatcaatg tgtgtagatt
    10261 atttagcatt ggaaagatat gtgaaagatt taaaacagta aaaaagataa ttctgtcaat
    10321 aattcccctc aacatactca gaagaatttt agtgtaaagt ctttgtaatt gtctatctta
    10381 gttaattaga tgtttactat tatttctata ttaatatata gctaaaatta ataaaataga
    10441 agtcattagc tgaattactt atgaatcaaa ataaatttta tatacaaaat gtcatttttg
    10501 agtacaccct aatcatacag atacagttgt tgaatttata gcaactaaaa cgtatgatta
    10561 gggtgtatat taattgtgga gtgaatatga atgattatag gttatgcaag agtatcttcg
    10621 acagatcaaa atttagagag acagatagat aatttgaaaa catttggcgt agagaaaata
    10681 tttacagaga aacaatcggg aaagtcagta gaaaatagac cagtatttca agaagcactt
    10741 aactttgtga gaatgggcga tagatttgta gtagaatcga ttgatcgttt aggtcgtaat
    10801 tatgatgaag tgattaacac agttaattat ttaaaagata aagaagttca attgatgatt
    10861 actagtttac ctatgatgaa tgaagtcatt ggcaatcctt tattagataa gtttatgaaa
    10921 gatttaatca tacaaatatt agcaatggtc tcagaacaag aacgaaatga aagtaaacgt
    10981 cgacaagctc aaggtattca agttgcgaaa gaaaaaggtg tatataaagg gcgtccgtta
    11041 ctttattcaa cgaatgcaaa ggatcctcaa aaacgcatta tttatcatcg agttgtggaa
    11101 atgttaaaag aaggcacagc tatcagtaag attgcgaaag aagttaatat aacaaggcag
    11161 actgtttata gaattaaaca cgataatgat ttggtttaat aaactttact tcgatgcaaa
    11221 tgagagcttc tcacagcatt tcaaaacaga tgatcataat ctgttatgac cttttaataa
    11281 taaaacagga aaagggagcg taaatatgcg ctctcttatt ttatatgtat ttatttagca
    11341 ataaaattta cggttctgtt gcaaagttga atttataata taattttaac aaaaaggagt
    11401 cttctgtatg aactatttca gatataaaca atttaacaag gatgttatca ctgtagccgt
    11461 tggctactat ctaagatatg cattgagtta tcgtgatata tctgaaatat taagggaacg
    11521 tggtgtaaac gttcatcatt caacgatcta ccgttgggtt caagaatatg ccccaatttt
    11581 atatcaaatt tggaagaaaa agcataaaaa agcttactac aaatggcgta ttgatgagac
    11641 gtacatcaaa ataaaaggaa aatggagcta tttatatcgt gccattgata cagagggaca
    11701 tacattaaat atttggttgc gtaagcaacg agataatcat tcagcatatg cgtttatcaa
    11761 acgtctcatt aaacaatttg gtaaacctca aaaggtagtt acagatcagg cactttcaac
    11821 gaaggtagca atggctaaag taattaaagc ttttaaactt aaacctgact gtcattgtac
    11881 atcgaaatat ctgaataacc tcattgagca agatcaccgt catattaaag taagaaagac
    11941 aagatatcaa agtatcaata cgtcaaagaa tactttaaaa ggtattgaat gtatttacgc
    12001 tctatataaa aagaaccgca tatctcttca gatctacgga ttttccccat gccacgaaat
    12061 tagcatcatg ctagcaagtt aagcgaacac tgacatgata tattagtggt tagctatatt
    12121 ttttactttg caacagaacc caaaatatta tttatgcttt tgaagagtct gaaacatcat
    12181 tacaccccaa ccatcaatta atgctaattg agtcatttct ttctctttct tcaaactcaa
    12241 ataatattaa ctacccatac gccaaattta gcatctatgc taccattaga aagtttgaca
    12301 tatagattct gataataaac gcaataaaat acaatatggt actgataaag catattcaca
    12361 aatggtttct actttaggag tattaccgga caatatcgat aggaataaaa aagcgatttt
    12421 acttgttgaa ggaaaaaagt gatattattt ttataagaca cttatgtgat aagttaaatg
    12481 aaggtaatgc tataccatat acatttagaa gaaaaaggtt tcgcactatt atctacaggt
    12541 ggtagcggaa atcttaaatc ttggattaat ttaaaagtta ttgaacaatt taatattcct
    12601 tggtgtatat tacaagattc tgacatagga cctaacgatg aaaatgcaaa tagagagaaa
    12661 aagcaagagc tagaatcgaa aggaataaaa atgtatctga ctaaaaaaga gaagttgaaa
    12721 aatataaagg ttccgatggt aacattaggt atgaatttac agaaatgata aatgattttt
    12781 taagcatagt agattaattc taatctttgc attcctctac taaccacttt ataattcagt
    12841 taacgaaaat gattgaaaaa gactaaatca attgtagatg aagtattaat tcaatttata
    12901 aaaaataagg tttattaaaa aaagtggcta ataattagcc acttttttta atttgagccc
    12961 ggagcttttg gatgtttcgt ttctgctggt gacgtttcac aagaatattt tgtatgatgt
    13021 ttacaagaag ctgcagttac aatttgagct gcagttgtcc aaggatttgg taagcctggc
    13081 tttacttgtg gagttttacc cataacgaat acctccttta tatatgtttg attagagaat
    13141 aacatattca acagtatatg tcatataatt ctgaatatct tactttaatt gttgtagctc
    13201 aatcatattt ttatattttg aatgtctaga taataactct gcatgagtac ccattcctgt
    13261 aatttcacca ttatcgataa aaattatttt atcagctttt agtacagtgg aaagacgatg
    13321 agctactatt attgttgttc tatcattgct aacatttttt atagattctt gtattttgtg
    13381 ttcactttcg ctatctaaat ttgaagtagc ttcatctaac aacaaaatcc caggtgtttt
    13441 tataaagttt ctagctatat ctaacctttg tttttcaccg ccagataaat taattccttt
    13501 ttctccaata agcgtattat aatcattagg taatttcatt ataaaatcat gcgttgacgc
    13561 tagcttagaa taataaatga tatcttctat acatggtgtc tcttgtagcg aataagtaat
    13621 attgcttttc actgttctat tcaatacacc agagttttgc ataacatatc ctaaattttt
    13681 tctccaatta attaaagaat agtcataaat agaattagtt ccatacttaa ttgaaccact
    13741 ttgaatttca tatagtcttg aaatcaaatt aagaatagtt gttttaccag aaccggaagg
    13801 acctactata gcagttattt tatttttagg tatagtaaag gataaattag taaaaacatg
    13861 gttgctttca tcataactga aagatacgtt attaaatgac aaatctactg aatttaaaat
    13921 gttaagatta ttattttgta aattttcttt ttcttcactt aatatttcag aaagtctttg
    13981 acttgcacct atagtttttt tatatcctgt aaagagacta gatatttttt caatagggtc
    14041 agttaattga gtcatataaa aaataagagc aataagcgtg ccaggagata tggctccaga
    14101 tgccactcta tatcctccaa aacctaatac gccacccatt gaaacaagca taattaacgt
    14161 agaaagaggt actacaattg aattgataac accttctttc acccccaaat aatatatatt
    14221 tcgtaaatat gaattagttt gacgaaactc tttattaatt gaatttgaaa gtttaactaa
    14281 tttgatttta gataaaacat gagctattac accactaacc ttagcagttt caagttgtgt
    14341 tttataagaa agtttttgca ttacattgct tattggtatt attaaaatga catacatagg
    14401 tattgaaata agagcaatta aagctgtttc ccaatctaac ataaataaaa aaaagattga
    14461 tccaaatagt acaattatcg atggaaaaaa agatggtata atttctgtaa tgaaactgtt
    14521 tattgattta gtgtcatcta taattctact taatagctca ccattactat ttttatcaaa
    14581 aaaagacgtt tttaatctta aaatatgatt ccaaactttg ttagttagag aataaattat
    14641 attttcgcct aatttagtta atagatatat acttaatccg ttcaatatgg aacttaacaa
    14701 aaaaatgaaa acaaatacta taatatagta tttgtttttt atgacttctg aaaaattatc
    14761 aactatattt tgagtgaata aaggaactat aagttgaaat atactaccta ttactgataa
    14821 taaaacagag aaaaatagta accatttagg aatttcaatc tcattaacta aatgtaaaac
    14881 tgggtttttt tgtttcatag tatcctccaa aatactttta ataaatttct aagttcttag
    14941 tgttttttaa tatacctttt tcagtaatga tatttttctc atttacaaca tacataaatg
    15001 gagtttgtga aatgaataat tcttcccaat taatatcttt tataatttta aaattgaatg
    15061 aacctttcgt attaaagtag ttatctacag caacttcatc gtctataaaa attacataga
    15121 cattatttaa gtggtcattt aagctcagca actcatctat aattttagca cagtgggggc
    15181 actgagtact taaacaaaaa atgtaatttt tactttctgt taaattaaaa tttttgtatg
    15241 ggaaaggtaa ggatataggg atgccttgca aatccaatat ttttctattt atattattat
    15301 agaaaaatat gatgcttata attaaaacaa acagtaacaa agctattatg tataccatga
    15361 atttcatcgt ccctttctat ctgattattg tttttatata gaaataaaaa cacaaaaaaa
    15421 cagagtttat aattatataa tatacgtgta tggtgatatc aaatttaaaa gagcaagata
    15481 taattaatac actaagcata ttcattgaca ctttggtcca gtttatatta cttgttaatc
    15541 ttgtaccaaa acaatcacat tcttggccct tttttcctat aaatattaaa accgttataa
    15601 ataaactaaa aaaaatatac attaataaga gtattgtcat actccatata gaaattttca
    15661 gtgaaagaaa tatagttagt ggaacaaaaa cttctataaa tattagtaaa aatgaacaaa
    15721 atttaattag ttttaaattc accttatgat ttaataatcc atatgtgttt agagaaaaat
    15781 gtgaaaaaga ataaattttt aaaattcctg ataccaatgt ttgaatcaaa atgtaagtta
    15841 tagcaatact aaatagaata tccatatatt ccactcctaa aagtatataa tataaaggat
    15901 aaaacgtttg gcataatttt tgaagttata ataagaaaaa ggtattatag taacacatgt
    15961 taaaataagg tataaccata tttaggaggt gctttaatgt ttgaaaagat gtttaaaatt
    16021 agtagtctac tatttttaat aaacatgatt tttgtagcaa taaaagatat agtattaggt
    16081 ggtgaaacta caagagccgg taataattta ttagttatta taactattat tttcactatt
    16141 tcaatgctta taacgacttt ttattatatt aaaaatagaa aaagtgattc ttcaaagaat
    16201 tataaagggt tatactatac tgttcttatt tttatgccaa tagtatggat attagttggt
    16261 tattacgtgt tttcaccatt gccagagttg ctttctcaca caaacacgta aaagtatatg
    16321 ttgaattaaa ttgttataaa agaaactaat agcccaaaaa aacttctttt tgaacaaatc
    16381 cccccatcac aattgttatt cgaattttaa atacacttat ttaaaataaa tataaaacaa
    16441 aaatagttct tcatttattc tataactaag cttatagtta atctaacgta atcaaagaat
    16501 gttcaaaggt agaatcaatg attctacctt ttctctctat atattaacat ataagattaa
    16561 aaatcctatt ttcaaaatat ttttcaaatc gctttttgtt agtttattta aagtgacttt
    16621 gggataagta ttttttattc acaataaatg aagattttcc tttaatttca ttaaactcaa
    16681 cttcatcttt aaaacgaact tgtaataaat catcaaagcc ctctaacgaa ttaatataac
    16741 ccttactagt atattcgaga atctttaaat ttagcgcttt ctcttttttt tcttcaattt
    16801 aatattatca ttgctctttt tataaaaata aattactaaa caaaataata taatagagca
    16861 taataacaaa acgataatcg tcatatccac ctcttaacta tttatatcaa tgactttata
    16921 gaatttattg ctttattgac ttttctactt tttatttttc tctttaatct tagctaataa
    16981 ttttgctgtt tcttcttcaa aaattgttgc taaagcaact aaaatatcta tgatttttta
    17041 caaacataca aaaacctcaa aatatttaga gctccttttt aaaaataaaa tatatcacaa
    17101 gaactaatta aattttaaat accctttttt aattttaagg gatcatttta aagaattagg
    17161 ggttattata ctttttatac ctaaaaacct atattggctc ttaaaacgca aatgagagcc
    17221 aaataaatat aaatgtattt cacaaacaaa aatttgagta aaaccagtgc cgaattttta
    17281 gacactggac catctacatg caaattaaaa attagcataa aatcatccaa aaagtagttc
    17341 tgatttttaa ttcttgcaga ggcatttttc ttttaaaaca gcaaaatagt ttgaatttaa
    17401 tgaataatat attaattatt cattaaaaat attatatata ggcatatttt gacgtcgcat
    17461 ataaagtgca tgagtttctt caagttcagc tttaatggat tgcattaaat atccttgcat
    17521 tgtttcgacg gtttcattct tttgtagcag cattgcttta aaacgtttca acacatttac
    17581 aatttcaaat tcaacatctt ctaaacgata ataggtataa tgtgcattat taaatgattt
    17641 cttccctttg agtaatacac ttttaataat tcggatttct ctaatttcaa atttacttaa
    17701 ataatcttga agttgttgtg gcaattcttc gagtacttgg aacttaagcg catcattatt
    17761 aaattcgatt tgttgatgat ttgtatgatc cgaatgatta tgacttgttg aattgttata
    17821 tatatcattc atatcatacg tatcattatt atcagtttct atattatcag tatcatttaa
    17881 gtcagtatca ttagactgtg aatttggaag ttcttgacca cttagattca cagttctaga
    17941 acttccgaat tcattgttct ggaactgtga atttggaagt tccttggtat gactgacttc
    18001 catatcataa ttgggtttta ataaatataa tctattgggt ttattaaggc caacacgttc
    18061 ttgagttagt aaattaaaat ttattaactc ttttttcaat tttatgattt tttgctctgc
    18121 ataacctaaa tactcgcaca aatgtttatt actgaaaata aagtaaatgt tattattttt
    18181 atctacccat tcattttgga tggataattc aaaacgatct tttaataatg catacataat
    18241 tttggcttct gcggacattt tcttaaaata tgtatcttca aataaatatt taggtagttg
    18301 ataaaatctt tcagttttta cttgtgataa attgtatttc tcaaaattgg gcataataaa
    18361 aacctcattt ccactttttt ggattgaggt aataaaacaa tttttacgta agttatatgt
    18421 tttgtgcttg cacttagatg attagatata tataatacaa gtatcaaaaa attatataaa
    18481 cagacgaatg cgaatcgttt tattaccgag agtcgatgct acgccaatag catcggctct
    18541 tttaatattc ataaagtaat attaacactt ttaagatcgt atataaagcg ttttaagtgt
    18601 agttaaaagc acattacaac ttcaaaatga taaagtttat tagtttagta cctaattaag
    18661 cgttgaaaat cttcgatagg tggctaatta ggttcttagg tggtaaaata ggcggtaaag
    18721 ttagatagca aaagatgaaa aaatatttgt taggtggtaa aatttaggta ctaaattagg
    18781 tacctaagga tggatgttat gaaaactatt aaaatggttg ctgatgaatt gaatgtaact
    18841 aaacaaacta ttgttaataa tgctaaaagc ttaaatatat cttttgaaaa agaaaatgga
    18901 attaattata ttaatgataa tgattgtttg aaaattatag aaaagattac taagaaagaa
    18961 agtacaacgc aaaataaaaa atcaataaaa aaagaaagat ttgatgaaaa tactgcagag
    19021 gttgaaaagt atatatataa taattcaaat agttttgaga cattaaaaac aaaagcaaat
    19081 gaattagaaa aacaaataga aatctttgaa actagagcta aaaatgatga aaaatatatt
    19141 gagaatttaa ctaaacaact agatcaacaa aatagcaatg ttaatacatt aaataaactg
    19201 ttggagaatc aacaaatatt agctttagaa agtaataaaa agattcaaaa actagaaaat
    19261 caattagaag aagaaagaca gcttaattac tcttttgata cagcgactaa tgatagacaa
    19321 agcattaatc cgcaagaagc aacttttact gaagaacctc aaaatatcaa ccaacaacaa
    19381 aagaaaagcc aaccaataga agcagaagta aatcataagg atataactga agagaaaaag
    19441 gatgacagtg aaaacgaaga cgtattagcg aaagatgata aaccatctga agaaatagag
    19501 aatgggcctg aggataggaa agaagaaaca tctaaaaagg ggttttggag acgtttgttt
    19561 ggtagctaaa ataattaatt aggcactaaa agtttataac ttttagtgcc ttttatatag
    19621 tgagaacttc tgataatcag taattatgtt aactcatcaa aaaggcttaa acgttgattt
    19681 cacagcgttt aagcctttgt cttgtgatta tcgtttattc aggttttata cattccctta
    19741 accacacgtt ttcatgcatt ttcattaaga gaatttttgt atctttattc agtcatcaat
    19801 gtctaagtgt tgcatacaat atgcgtgcat actgtatgcc tgtatatact tgaaaagtta
    19861 tatatttaaa cacaacttta aaaaacttac ttacatctat ataataatca atgtaagcaa
    19921 gttggattga tggtggctaa tctcatgaaa atggggtgat gcctatggtt ttggtttttg
    19981 ctcctagaaa ggactagcat tgtctgatta tgaaatgcta atgattgttt tgacaatcat
    20041 tagtttagta ttaattagaa acgaccaaaa aaaatagacc atctccactt tgacaagtag
    20101 atagtctatt taaaaatttt ttatcgaaag tcaccgtctt tttaacgggc ttactaaggc
    20161 acaagtgtta ccagcacttg tgtcttttct tttgtcaatt tcagtatatc ctttcttatg
    20221 ctttttgtaa aacaatctcg ttgtatatgg ttgtttttcg ttacttttcg ttattttgct
    20281 ctattcttcc caatccattt taagttgttt taaaaaaaac tcgcgttctt tctcaaattg
    20341 aggatcatca gtttcatgtt ctttattttt ataagtagga ttttctaatc agttaggagt
    20401 tttctcacga ctaatatatt gccgttgttt acctactttt agtcttttgg ggttgtcgtt
    20461 tattgtgaat gcgtttctca gcgtcaaagg taaactctaa ccattcaatt ttacgtcctt
    20521 ttttagattt gattttatta atatttaaat ttttgaaaat aaagcttaat tcgttaatga
    20581 taggcgttaa aactttttgg ttaatatgtg tcatgcgata actgttcggg atatctaaaa
    20641 gttctttaaa atcaaaaatt tgtattttaa agtaaacaat atgtagattt aagatgtgtt
    20701 atttctttta attcaaattt agtgaaattt gctattatct catttaaaac atatttagat
    20761 ttgggattaa tactaacgat aagtttttgt gtatatacat caacttcata accagtaaat
    20821 agtacaaatt ttttaaatga taaaccactt cgttctatgt aagttagact tagcaattta
    20881 ccataaacat gtcctaaatt taaaaaaatt ttttgagaac gatgaatagt aattacttaa
    20941 atgacgtaat tcttcaaaag gaatagtaac ttctttgaca ctatgttttt ttaatttatt
    21001 gcaaagacta agaaatatta atttctgtac ttatgaattt tctcggcata aatgctctgt
    21061 tataattaaa atatcttttc ttgatttact gttattatct ttcacttata tcatccaaaa
    21121 agtgagtaag agctaccaaa attttaagtg gtagctcttt atttttaatt ttaagggggg
    21181 attttgaaaa attagagtta tttatataat ttattaccta aaattttaaa ttagccctta
    21241 aaacacaaat gagagccaaa taaatataaa tgcatttcaa aaaaacttga gcaatcattt
    21301 ttgttgacca ctataattac aaaggagtta aaaataaaaa attttgctaa cgttattcca
    21361 agtgtataaa atatattaag tcaaaattag tcttcttttt ctttaaaacc attttctttc
    21421 attttcttct cagttttctt catactaatg cttgtccctg tattaccagc aatattaaca
    21481 atacctttag attttaaagt atcaatatca gccttttcaa aatctacatc tatagtttct
    21541 acgaatcctt catcattctc tttaatagat tcctttacac ctttaacgtc ttgtattttt
    21601 tcactttgtc tctctattga ttccttaacc aattttttag atgcatcatc agaaatacca
    21661 aaatcactat atttcaaagt atttacagat ttttgtttaa ttattctgtc ccctttatat
    21721 gtataagtta cctccacttt cacattatct ttttttccaa caaatgtttt agttttttta
    21781 tttccacaag cagataacgt aattaaaata acaatacttg ctaccaaacc aataattttt
    21841 tcataattta atctccttta ttttaataat atataaaata tcatataccc ttttccctaa
    21901 gtatatgaca cttaaattaa ttaaaaatat attaggttta atgagagtaa aataaatata
    21961 ttttaatttc acatcacaaa attttagcaa aaccagtgtc gaatttttta gacactggcc
    22021 atctacatgc aaattaaaaa ttggcataaa atcattcaaa aagtagttat gatttttagt
    22081 tcgtacagag gcatttttct tttaaaacac caaaattttg atttgaaccc caatcatgaa
    22141 ttaacatgag ttaagagcat aagggaatcc agtaccacct aaggtggtat tcagcatagc
    22201 tgaaggatta tcttacattc accttgatta attacttttt ttaaaactat tataaacatt
    22261 gatataacaa tatttagagt taatattaaa tagaaattga tcgagattat aacccttaat
    22321 attgcatact atttacaatt gttacaagac cactttaaat tgtttgaata ctattatttt
    22381 tgttgatttc ataggcttca gtcatcctca atcctataaa taggattaat ttttttaccc
    22441 aaatcctatt aatcctacta cttttagtat taatatcaaa aataaaatca ctcaaaagta
    22501 agctaagcaa ttcattcatt tgtttcactt tttaaaattg attaaatact tttttctcaa
    22561 tatcaaactc aataatgatc atattattta ttttttagtt caaaaaaaga gaaagaataa
    22621 aacaatttct atacgtttct atgctcaatt ttattaaaaa gtgaatcgaa ataaagatca
    22681 ttttatcttt ttattaacta gagaattaaa aaatataaaa tgcataataa gattcatcga
    22741 aatgattata ctcaaaaatt tttattttaa tcttcctaaa ttttaaattc aactcttatt
    22801 tacgttttaa gagatatgaa attatttttt tgtataacaa tatataacat tctaattatt
    22861 ttagtgagta tcaagattat tttaattaac tttaaaatgt taaataaaaa gcaaagtatt
    22921 atttatttta gactgtctaa agaaataaaa tagaacggaa aacatgccaa atggcatttt
    22981 ctaaaagaag gtgatttgac agtatatttt tatatttgga ttaaaaaaga gtatttaacg
    23041 agtgaacttt ttgatttaac agaaagtgaa agacaagaaa ttaatcatca aatgattgat
    23101 gaaattgaag aagaaaaata aaaataaatt ttcttaaaca ttagcaaaaa gctagcgctt
    23161 ttttgttgaa aatatgttaa aaatgcctgg gtacaaacgg ggtactgaca caatatatag
    23221 gggtacaacc ggggtacaat cgcaatttgt aggggtacaa tcggggtaca aaacgaaaaa
    23281 aatgtatacc tttttaaaat ctctgtatcc cttgaaatgt ctggcttcgc cagaccatac
    23341 attttttaat gtatgcaaat ttaccttatg ctcttacaaa gaatttggag ctaattcaaa
    23401 atttggtgtt tttttgaaag taattactct gcaggaacta aaaaagttga tgaaattttg
    23461 taaagtttta tctcaatttt tagtttgaat gtcaatgcat aatgtctaaa aattagctat
    23521 tggttttgtg cgaattttta agatatgaga gtgaaattta ttcgcctatc tctcatttgc
    23581 tattaagagt cgataaatca aaaatacaga aaaagctact tataatcatt ttgtactgaa
    23641 ccccaaaagt tgtactttgg tttagccaat aatatccata accattttaa atcaaattcc
    23701 aggatactag aaatttaatt aagaacatta ttgattaaat atagaatgca caaaaaattg
    23761 ttataaaaaa ttctcaggtg atatagcata tgtgtatact gcataattaa atgaagagca
    23821 tatgtagaat attagaattt tagtaaatag atgaggagaa aatagatggt atcaattatt
    23881 atccattcga taaaaatact gtttaggttt atggattttg aaaaaaagag tgattattac
    23941 tttatgttat tcattaatag cattattgtg ggaggtattt tttctatacc tgtatgtctc
    24001 gattatttat tactaataaa attacctaac gaactattat cggtatttat ttcaattatt
    24061 acatttggac ttttgttatt ctttttcgca agtgctattc tattgattaa agagatgatg
    24121 aattttttta ttgcatttat cgataaaaag aatagattgt ttgttaagag aacttttaat
    24181 agaaagtatt acgaaaatac gatgaaatta gattcagaag atgatataaa aaggcaatta
    24241 tatgaaaatg atatatcata tccattgcga aggttatata aaggtataca ttataaatac
    24301 tacaatcagg atggagaaaa acttgaagaa attgcgctta tgttcaacaa gttattttat
    24361 aagagattaa tttgtagcaa ggaacatgta aagaaaaaaa tactatggct attaatgaca
    24421 ttattaacaa ccatagttac aactatatat cttttaataa agcattttac taattttcaa
    24481 tccttttata tgccaataat tatattaact attcataata tatattactt tctaagtgtt
    24541 ggcatatttt caatggttat aggaactata tacaaagaaa atctaaaatc taaactatta
    24601 atattaagat ttttaaaaaa gggaatttaa tttttgttac aaatccattt aatcaatttt
    24661 cggacacaac gaccgatagt tttaaaaaat agtattaaca aaattaggga agatatcaaa
    24721 aggataagta tagctattat aatatgatat tttgctaaaa gattaaaacc taaaaaaaca
    24781 taccataaaa tagctggaac gaaagagagt gctgttaata ttgcttccgt ataggctata
    24841 tattttgatt ttaaatgtgc tctattttca tcagatgtta ttagtttatc atcgactttt
    24901 tgataaaatg aaacaatttt ataagtagac aatagaacaa cattaaatat tatcggaaat
    24961 gctgtagtaa agatgtggtt ctgttgcaaa gtaaaaaata tagctaacca ctaatatatc
    25021 atgtcagtgt tcgtttaact tgctagcatg atgctaattt cgtggcatgg ggaaaaaccg
    25081 tagatctgaa gagacctacg gttcttttta tatagagcgt aaatacattg tatataatct
    25141 atggaattcc agcaattatt tattcaataa tttactataa aactcaaaga atagaattac
    25201 ctatcataat tcatgtaatc aataatttac tcccgttttt aaattaatgt tgctttattg
    25261 acgttgagcc tcggaaccct taacaatccc aaaacttgtc gaatggtcgg tttaatagct
    25321 cacgctatac cgacattcgt ctacaagttt agttaagggt tcttctcaac atcaataaat
    25381 tttctcggca taaatgcgta atctactttt cattttttat tctgcctata tttgcaattc
    25441 caacagttat tggacacatt gccagtaacc aactaatcat gatattagaa tctcctaaaa
    25501 aataataacc aagaaaagtt aatacaccta caagtaataa aaaataatta aaagacaatg
    25561 aatttcctaa tttagttttt ttaggcatac cttttttcac gctccttatt ttttgtgcta
    25621 aaaaatattt aaagccttaa taaaaattat aatgctttta tttttaattt taagggggtt
    25681 ttttgaagaa ttagtggtta tttatatagg ttttattacc taaaaactta tattggctct
    25741 taaaacgcaa atgagagatg aataaatata ttttaatttc aaaaacaaaa ttttgagcaa
    25801 aaccagtgtc gaatttttta gacactgccc atctacatgc aaattaaaaa ttaatataaa
    25861 atcattcaaa aagtaggtct gatttttagt tcttgcagag gcgtttttct tttaaaacac
    25921 caaaattttg atttgaaccc aaatcatgag ttaagagcat aagggaaatt tgccaccttt
    25981 tataaaggta ggtctggcga agccagacat ttcaaaggtt tcagagtctt tcttttggtg
    26041 cctaaatttt gtgtttgtac ccaaaatgta cccctataaa ttgtgcttgt acccaaaatg
    26101 ttcccctaca tattgtatct gtacccattt tgtacccatt cttttttacg acttttcaat
    26161 aacaaacact agctttttta gttaaagctc cctatttttt agagataatt ttgttttcga
    26221 agtgcccaat ttctgtaatt gaatgttttt ttctttatca attgtttgaa ttaaattacc
    26281 atcttcagcg ttatctaaat ttaaaagttt atgtttttat ttaagtaatt acaccgaaat
    26341 tagtatacgt tttcgatata aaattcattc taagtcatta acaatttctg cattttttca
    26401 gggggtcttg ttaaataatc gagcgaaata atggaatatt ttgattaatt tttgtaagat
    26461 ttatgcgccg ttttttcata tgttagacaa gcgtaaaaca aaagtagagc gcgcatttat
    26521 gctaagaaat tttaataatg ttgtgagtct gcttaactaa attttaagat gaatgtcgta
    26581 tggtgtgagc gatttagtcg acaattttat aagtttgaaa attgttaaga gcttcaaaga
    26641 tcaacgttaa tacattaatt tcaattctaa ttctgtactt attttacagt taataaatta
    26701 agtattatta agctaataat aattattacg agattgatta agtttataaa aatcttaaag
    26761 attttcttgt cattgtattc tggcctttta tatagaagca tgtaatacat aaacaaattt
    26821 gctgtaaaca tttcgaatat tgaagctaag attccaaaat gtatgttcat aaaaccagtt
    26881 tgaattaaaa aatatgagaa tgaaattatt aaaaataata agatttcata aattaaaaga
    26941 atcatgattt ttctcctata aattaaagct aaagaaaaca taaatcatca tcaattttct
    27001 aatgtttaaa gcgaaaatta ttaggaaagc tgttaaacaa aatgatgcaa attttagagt
    27061 atataggagt aaagaaaagc atattagatt ttaaaaggta ttaaaaaagt attataggta
    27121 aataagaata aaattaataa tgctattaaa agtgaaattg aaaatttaat tttaagtgag
    27181 gttcaaaaga agaattgatt gttgtttgaa tgattgagaa aaatttgaag ttacctttat
    27241 tttactaaaa tcaagttcgc tattattact ttttaatact tatatagacg taaaaccact
    27301 tagtaaaagt catcgtatat tatatgacaa cagggaaaac tatttattgc tatattttca
    27361 ggagattaag gaaatacttt aaattgtata tcgcatataa atctgtcata tagttattag
    27421 taaactagtt taatagttta ctaataaact tatatactag taaacaagta aatttattta
    27481 cttatagtga tgtgtttaat tactataata aacttgaaat atacttataa agtatctctt
    27541 ttgcctctag atattataga aatagatctc actatcatta cataaaatga cttatcggaa
    27601 gttatctatt atcccttatt cagagatgat ataatataca ggtcgcctat ctctcaggtg
    27661 tcaatttaga cgtagagagg aggtgtaatt atgcttgata actttgttca catcatgacc
    27721 acagcagcga gtggttgtat cgtcgcatta tttgcgcatt ggctacgtaa tcgcaacgat
    27781 aagaaaaaat aggcgactat agccacacct aaaaatcccc tcactacttc cgatagtgag
    27841 gggattggtg tattatgctt aataactttg ttaattagat tataacactg gttagtagag
    27901 gaatgcaaaa aactaattta aagttttttt acatatgaat tagtaccatt aaaatggttt
    27961 ggttcgatta acctagcagc attaatcttt ccttttaatg atattacttg atgttttcgt
    28021 tcctggttat tttttatatc ttcaaaatct tttaaaatac tcattcttaa attatttggg
    28081 atttttaact catgattctt taatataact cctgtgattt ttgcaccttt tttaactgac
    28141 ttataatttg tttttttata ctttaaagaa tgatcgaatt ttcgagcttc tatgtcgata
    28201 taattaatta atttttgata attaaaagaa ttccctttgg aaaaagttaa atcatctaca
    28261 tataaagtca ttttacaatt gaactcttga ctaacattaa acatattaat aaacatttct
    28321 tcatatgcaa aataagcaag aatttggcta cttggagaac cagtaggtat ataatttaaa
    28381 gtagttatat cagacaataa ttttgcaacg tctggtgaag ttaacagttt ttttgcaaaa
    28441 aattgataca ccctatcacg agagcaatta ttatagaaac tacgaatatc tgttgtacaa
    28501 acatattgag ctccaatgtg ataatgagca ttatctaaat atgatttttc tttggtagat
    28561 gatatgaccc aatcaggctt ttcaatttta ttgagtaaat tgagtactct tttttgtata
    28621 actttcaact cttttttagg agctgtaatt tgtcttttgt tattgaatgt atagtattct
    28681 tgttcaatag actttgaaag tctatttaga ttatttaaat cagttttaag taatctagct
    28741 aactttttct ttgatttaca tttataaaaa gcacactgat ggattggata tgtttttaat
    28801 tgcttcaaat catttttcct ccaattcatc agtgtgttta ttcaaaattt ttattaatct
    28861 tttttgtata aacatctcag gtttactttt tcgtctgttt tcactatagt cttcagccat
    28921 taacataata gtagaaactt ttatttcaaa tacttgagaa tatttattta ataattctaa
    28981 agaaggagtc tttttactgt tttctatttc agaaagatag ctaggagata taccaatgtc
    29041 atgagctaaa tcttttgctg aaacggagta tagtagtctt aattttttta aaacttctcc
    29101 tattttcata ataattcacc tctttattaa aaaagaatca ggaaggaact aacacattac
    29161 ttaaatagtt cagtaacaga attaagtagc ttgatagata aatggacaat atccagtaat
    29221 tctttgtaaa actgaaattt ccatgtgcta ctattcttag ttagttttac tttttttgaa
    29281 gaacttttat aatttttcat agttttctac tccttctgtg tctattggat tatataaata
    29341 tatagacacc cctcagaaga aacggtacaa aaaaagttca gccttcccga taaatttcgt
    29401 gttcggaggt cccctccgaa gaacacgagg cgcttgtagc gccgaggtct tctcggacta
    29461 cgcaatcatc gtgcagcgcc ttaaaaggta gaatgaatag ttaagttcat tcctcgagca
    29521 agttgctcca atgtataggg gattaccatt aaaagttctt gaatataata taacacaaag
    29581 aaattttatt agcaaattaa attcgctaat agtgaattta agcgtattta tataaagaaa
    29641 tttatcttgg tgaaggaaat cttatatatt aaatatatgc taatttacag tacgctctaa
    29701 ataaacaaaa atagtcctct tattaaaata agaggactat ttttgtttaa aattattcaa
    29761 gaccattcgc tttctaacat actcatttgc cataaattat aatattctcc atttaatttt
    29821 ctaaagtctc ttttttctcc ttcttttata aatccaatct ttttgtaact tttaatagct
    29881 gatttattaa aggcaaaaac acctaattca attctgtgta gtcccaaatc ttcaaaagcc
    29941 tttttcaata atttctttat tattttaggg cctaatcctt ggccacgcat ttgcggatca
    30001 cctactaaaa ctttacttaa cgtggcggaa caatttttaa aatctatatt atttaaagca
    30061 atatgaccta taattttttt tgaattattt tcttcaatga taactttata aattatttta
    30121 ctagaatttt ctttatttgt gtctttaata tattccttta attgttcttc atctagggga
    30181 taattaaaat ctgtacctgc ccatttgact aaaagttcag gagagtttat ccagtttatt
    30241 aataaatcaa aatctttctc ctcaaaatat tcaaacttaa tcaataaatt actccttaaa
    30301 taataggtta ttaactataa aaattcagtg aatgttgcaa tataaacaac cactacaatt
    30361 ttttgatact ttcttcatca actttctatc ttaaattttc gattttttat aaagcgtttt
    30421 gtattatcta aataactctt tacaatttac tgatttttaa gcttttgcta atagatttat
    30481 gcaactttaa tattataagt aaatctatgc acttcatcat taaatttaaa ttctgcccaa
    30541 attttataca tccctttttt aggaaaatga gcataaaagg ttgtagaatc aggtgattct
    30601 gggtgaacat gaatataatc agttaattgc tcatcaaata taatcacatg tcctaaagct
    30661 cctaaataag gttggggagt taattctgta ttgaaagtta aagggacatg ttcatcttct
    30721 ttagcactta tagaatttaa agttacatga actcctttgt taacttttac ccaattttta
    30781 tcagaattta aagatgttgt agaggttatt ttatctccaa tttgcagttc aataggatga
    30841 acg
//
