LOCUS       NZ_CP033630            23185 bp    DNA     linear   CON 26-NOV-2023
DEFINITION  Klebsiella pneumoniae strain 4743 plasmid unnamed5.
ACCESSION   NZ_CP033630
VERSION     NZ_CP033630.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN10343201
            Assembly: GCF_003790485.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 23185)
  AUTHORS   Sahl,J. and Zarrilli,R.
  TITLE     Diversity, virulence, and antimicrobial resistance in isolates from
            the newly emerging Klebsiella pneumoniae ST101 lineage
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23185)
  AUTHORS   Sahl,J. and Zarrilli,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2018) Pathogen and Microbiome Institute, Northern
            Arizona University, PO Box 4073, Flagstaff, AZ 86011, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: UniCycler v. v0.3.0b
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 35.0x
            Sequencing Technology             :: Illumina MiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/26/2023 02:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,816
            CDSs (total)                      :: 5,695
            Genes (coding)                    :: 5,538
            CDSs (with protein)               :: 5,538
            Genes (RNA)                       :: 121
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 71 of 157
            Pseudo Genes (incomplete)         :: 85 of 157
            Pseudo Genes (internal stop)      :: 30 of 157
            Pseudo Genes (multiple problems)  :: 23 of 157
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033630.1.
            Bacteria and source DNA available from Dr. Jason Sahl, Northern
            Arizona University.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..23185
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="4743"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed5"
                     /geo_loc_name="Italy: Aosta"
                     /lat_lon="45.738887 N 7.42618659 E"
                     /collection_date="2013-11-24"
                     /collected_by="USL Valle D-Aosta"
     gene            <1..497
                     /locus_tag="DPQ49_RS29590"
                     /old_locus_tag="DPQ49_29550"
     CDS             <1..497
                     /locus_tag="DPQ49_RS29590"
                     /old_locus_tag="DPQ49_29550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /protein_id="WP_258184169.1"
                     /translation="DQVRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESR
                     KQKEKKAKDAENKLNEEKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGG
                     GGKRARWYGDKKRKIYEWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKY
                     L"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            507..764
                     /locus_tag="DPQ49_RS29595"
                     /old_locus_tag="DPQ49_29555"
     CDS             507..764
                     /locus_tag="DPQ49_RS29595"
                     /old_locus_tag="DPQ49_29555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            849..1085
                     /locus_tag="DPQ49_RS29600"
                     /old_locus_tag="DPQ49_29560"
     CDS             849..1085
                     /locus_tag="DPQ49_RS29600"
                     /old_locus_tag="DPQ49_29560"
                     /inference="COORDINATES: protein motif:HMM:NF014457.3"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_123836186.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANGTVAKLAMRQPFVLFKGLTF
                     QKLCLPGAFRPGDHHNKMLRPGLCVVHASPQYL"
                     /name="colicin release lysis protein"
     gene            complement(976..1680)
                     /locus_tag="DPQ49_RS29605"
                     /old_locus_tag="DPQ49_29565"
     CDS             complement(976..1680)
                     /locus_tag="DPQ49_RS29605"
                     /old_locus_tag="DPQ49_29565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            1716..1826
                     /locus_tag="DPQ49_RS29610"
                     /old_locus_tag="DPQ49_29570"
     CDS             1716..1826
                     /locus_tag="DPQ49_RS29610"
                     /old_locus_tag="DPQ49_29570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368419.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_116938357.1"
                     /translation="MTTDYLQQCQANYIRDVQGGTVAPSSSSELTGIAVQ"
                     /name="colicin release lysis protein"
     gene            3307..5271
                     /locus_tag="DPQ49_RS29620"
                     /old_locus_tag="DPQ49_29580"
     CDS             3307..5271
                     /locus_tag="DPQ49_RS29620"
                     /old_locus_tag="DPQ49_29580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            5271..6002
                     /locus_tag="DPQ49_RS29625"
                     /old_locus_tag="DPQ49_29585"
     CDS             5271..6002
                     /locus_tag="DPQ49_RS29625"
                     /old_locus_tag="DPQ49_29585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            6009..6539
                     /locus_tag="DPQ49_RS29630"
                     /old_locus_tag="DPQ49_29590"
     CDS             6009..6539
                     /locus_tag="DPQ49_RS29630"
                     /old_locus_tag="DPQ49_29590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(6567..6746)
                     /locus_tag="DPQ49_RS29635"
                     /old_locus_tag="DPQ49_29595"
     CDS             complement(6567..6746)
                     /locus_tag="DPQ49_RS29635"
                     /old_locus_tag="DPQ49_29595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            6815..7192
                     /locus_tag="DPQ49_RS29640"
                     /old_locus_tag="DPQ49_29600"
     CDS             6815..7192
                     /locus_tag="DPQ49_RS29640"
                     /old_locus_tag="DPQ49_29600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(7254..7553)
                     /locus_tag="DPQ49_RS29645"
                     /old_locus_tag="DPQ49_29605"
     CDS             complement(7254..7553)
                     /locus_tag="DPQ49_RS29645"
                     /old_locus_tag="DPQ49_29605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(7543..7806)
                     /locus_tag="DPQ49_RS29650"
                     /old_locus_tag="DPQ49_29610"
     CDS             complement(7543..7806)
                     /locus_tag="DPQ49_RS29650"
                     /old_locus_tag="DPQ49_29610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(8112..8531)
                     /locus_tag="DPQ49_RS29655"
                     /old_locus_tag="DPQ49_29615"
     CDS             complement(8112..8531)
                     /locus_tag="DPQ49_RS29655"
                     /old_locus_tag="DPQ49_29615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            8934..10619
                     /locus_tag="DPQ49_RS29665"
                     /old_locus_tag="DPQ49_29625"
     CDS             8934..10619
                     /locus_tag="DPQ49_RS29665"
                     /old_locus_tag="DPQ49_29625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            10629..10886
                     /locus_tag="DPQ49_RS29670"
                     /old_locus_tag="DPQ49_29630"
     CDS             10629..10886
                     /locus_tag="DPQ49_RS29670"
                     /old_locus_tag="DPQ49_29630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            10971..11207
                     /locus_tag="DPQ49_RS29675"
                     /old_locus_tag="DPQ49_29635"
     CDS             10971..11207
                     /locus_tag="DPQ49_RS29675"
                     /old_locus_tag="DPQ49_29635"
                     /inference="COORDINATES: protein motif:HMM:NF014457.3"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_123836186.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANGTVAKLAMRQPFVLFKGLTF
                     QKLCLPGAFRPGDHHNKMLRPGLCVVHASPQYL"
                     /name="colicin release lysis protein"
     gene            complement(11098..11802)
                     /locus_tag="DPQ49_RS29680"
                     /old_locus_tag="DPQ49_29640"
     CDS             complement(11098..11802)
                     /locus_tag="DPQ49_RS29680"
                     /old_locus_tag="DPQ49_29640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_123836187.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYCRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            11838..11948
                     /locus_tag="DPQ49_RS29685"
                     /old_locus_tag="DPQ49_29645"
     CDS             11838..11948
                     /locus_tag="DPQ49_RS29685"
                     /old_locus_tag="DPQ49_29645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368419.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_123836191.1"
                     /translation="MTNDYLQQCQANYIRDVQGGTVAPSSSSELTGIAVQ"
                     /name="colicin release lysis protein"
     gene            complement(14195..14320)
                     /locus_tag="DPQ49_RS29690"
                     /old_locus_tag="DPQ49_29650"
     CDS             complement(14195..14320)
                     /locus_tag="DPQ49_RS29690"
                     /old_locus_tag="DPQ49_29650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368419.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_123836188.1"
                     /translation="MDDKFITNDYLQQCQANYIRDVQGGTVAPSSSSELTGIAVQ"
                     /name="colicin release lysis protein"
     gene            14341..15045
                     /locus_tag="DPQ49_RS29695"
                     /old_locus_tag="DPQ49_29655"
     CDS             14341..15045
                     /locus_tag="DPQ49_RS29695"
                     /old_locus_tag="DPQ49_29655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_123836189.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYVISYRELQEMLAERGVNVDHS
                     TIYRWFQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTTYATIKGIEVMRALRKGHASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(15257..15514)
                     /locus_tag="DPQ49_RS29705"
                     /old_locus_tag="DPQ49_29665"
     CDS             complement(15257..15514)
                     /locus_tag="DPQ49_RS29705"
                     /old_locus_tag="DPQ49_29665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(15524..17209)
                     /locus_tag="DPQ49_RS29710"
                     /old_locus_tag="DPQ49_29670"
     CDS             complement(15524..17209)
                     /locus_tag="DPQ49_RS29710"
                     /old_locus_tag="DPQ49_29670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            17612..18031
                     /locus_tag="DPQ49_RS29720"
                     /old_locus_tag="DPQ49_29680"
     CDS             17612..18031
                     /locus_tag="DPQ49_RS29720"
                     /old_locus_tag="DPQ49_29680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            18337..18600
                     /locus_tag="DPQ49_RS29725"
                     /old_locus_tag="DPQ49_29685"
     CDS             18337..18600
                     /locus_tag="DPQ49_RS29725"
                     /old_locus_tag="DPQ49_29685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            18590..18889
                     /locus_tag="DPQ49_RS29730"
                     /old_locus_tag="DPQ49_29690"
     CDS             18590..18889
                     /locus_tag="DPQ49_RS29730"
                     /old_locus_tag="DPQ49_29690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(18951..19328)
                     /locus_tag="DPQ49_RS29735"
                     /old_locus_tag="DPQ49_29695"
     CDS             complement(18951..19328)
                     /locus_tag="DPQ49_RS29735"
                     /old_locus_tag="DPQ49_29695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            19397..19576
                     /locus_tag="DPQ49_RS29740"
                     /old_locus_tag="DPQ49_29700"
     CDS             19397..19576
                     /locus_tag="DPQ49_RS29740"
                     /old_locus_tag="DPQ49_29700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(19604..20134)
                     /locus_tag="DPQ49_RS29745"
                     /old_locus_tag="DPQ49_29705"
     CDS             complement(19604..20134)
                     /locus_tag="DPQ49_RS29745"
                     /old_locus_tag="DPQ49_29705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(20141..20872)
                     /locus_tag="DPQ49_RS29750"
                     /old_locus_tag="DPQ49_29710"
     CDS             complement(20141..20872)
                     /locus_tag="DPQ49_RS29750"
                     /old_locus_tag="DPQ49_29710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(20872..22836)
                     /locus_tag="DPQ49_RS29755"
                     /old_locus_tag="DPQ49_29715"
     CDS             complement(20872..22836)
                     /locus_tag="DPQ49_RS29755"
                     /old_locus_tag="DPQ49_29715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(22849..>23185)
                     /locus_tag="DPQ49_RS31000"
                     /old_locus_tag="DPQ49_29720"
     CDS             complement(22849..>23185)
                     /locus_tag="DPQ49_RS31000"
                     /old_locus_tag="DPQ49_29720"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227541941.1"
                     /translation="HPQKSTVLDAPGEAAKLLLILRVVSRSLWRTLTGAGTPEKTALGC
                     RLFLSHAGACSLFLRGCAFSAWGGKRLASVVKAERNHHGRDRRRHALGHVRGLCSGGCT
                     SRRQTIV"
                     /name="hypothetical protein"
     BGC             3934..22209
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(1930..2508)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(12052..12630)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          13514..14092
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5272..5999
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.3599999999999998e-150"
     Typing          complement(20145..20872)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.3599999999999998e-150"
ORIGIN
        1 aggatcaggt tcgctatctt gataaggata ttcagaatca gaatgagaaa ttaaaagctg
       61 cccagacatc tttaaacgaa atgaatgaat ccttatccag ggataaggct gcgctttccg
      121 gggcgatgga gagccggaaa caaaaggaga aaaaagcgaa ggatgcagaa aataaattaa
      181 atgaggaaaa gaaaaaacct cgtaagggaa ctaaagatta cggccatgat tattttcctg
      241 atcccaagac tgaagatatt aaggggttgg gagagttgaa agagggtaaa cctaaaaccc
      301 ctaaacaagg tggtggtggt aagcgggccc gatggtatgg tgataaaaag cgtaaaattt
      361 atgaatggga ttcccagcac ggtgagcttg aagggtaccg cgccagtgat ggcgaacacc
      421 tcggggcatt cgatccaaaa acgggtaagc aggttaaagg gccggatcca aaacgaaaca
      481 ttaaaaaata tctttaagag gtaaatatgg ggcttaaatt acatattcat tggtttgata
      541 agaaaaccga agagtttaaa ggtggtgaat actcaaaaga cttcggtgat gatggttctg
      601 tcattgaaag tctggggatg cctttaaagg ataatattaa taatggttgg tttgatgttg
      661 aaaaatcatg ggtttcgata ttacagccac actttaaaaa tgtaatcgat attagtaaat
      721 ttgattactt tgtatccttt gtttaccggg atggtaactg gtaagcaaaa gttatcaagg
      781 atgatttgaa atacagactt ccggtgttca gggatgaata ccggggtttt taaatacagg
      841 gaaggtatat gaaaaaggta aaggttgttt ttctttttat attgattttt tcaggctttc
      901 ttctggtcgc atgtcaggca aacggcactg ttgcaaagtt agcgatgagg cagccttttg
      961 tcttattcaa aggccttaca tttcaaaaac tctgcttacc aggcgcattt cgcccagggg
     1021 atcaccataa taaaatgctg aggcctggcc tttgcgtagt gcacgcatca cctcaatacc
     1081 tttgatggtg gcgtaagccg tcttcatgga tttaaatccc agcgtggcgc cgattatccg
     1141 tttcagtttg ccatgatcgc attcaatcac gttgttccgg tacttaatct gtcggtgttc
     1201 aacgtcagac gggcaccggc cttcgcgttt gagcagagca agcgcgcgac cataggcggg
     1261 cgctttatcc gtgttgatga atcgcgggat ctgccacttc ttcacgttgt tgaggatttt
     1321 acccagaaac cggtatgcag ctttgctgtt acgacgggag gagagataaa aatcgacagt
     1381 gcggccccgg ctgtcgacgg cccggtacag atacgcccag cggccattga ccttcacgta
     1441 ggtttcatcc atgtgccacg ggcaaagatc ggaagggtta cgccagtacc agcgcagccg
     1501 tttttccatt tcaggcgcat aacgctgaac ccagcggtaa atcgtggagt gatcgacatt
     1561 cactccgcgt tcagccagca tctcctgcag ctcacggtaa ctgatgccgt atttgcagta
     1621 ccagcgtacg gcccacagaa tgatgtcacg ctgaaaatgc cggcctttga atgggttcat
     1681 gtgcagctcc atcagcaaaa ggggatgata agtttatcac caccgactat ttgcaacagt
     1741 gccaggcaaa ctatatccgg gatgttcagg gtggaacggt ggcaccatcg tcctcctctg
     1801 aactgacggg gatcgcggtt cagtagaaaa gatcaaagga tcttcttgag atcctttttt
     1861 tctgcgcgta atcttttgcc ctgtaaacga aaaaaccacc tggggaggtg gtttgatcga
     1921 aggttaagtc agttggggaa ctgcttaacc gtggtaactg gctttcgcag agcacagcaa
     1981 ccaaatctgt ccttccagtg tagccggact ttggcgcaca cttcaagagc aaccgcgtgt
     2041 ttagctaaac aaatcctctg cgaactccca gttaccaatg gctgctgcca gtggcgtttt
     2101 gcgtgctttt ccgggttgga ctcaagtgaa cagttaccgg ataaggcgca gcagtcgggc
     2161 tgaacggggg gttcttgctt acagcccagc ttggagcgaa cgacctacac cgagccgaga
     2221 taccagagtg tgagctatga gaaagcgcca cacttcccgc aagggagaaa ggcggaacag
     2281 gtatccggga aacggcaggg ttggaacagg agagcgcaag agggagcgat tcatcggaaa
     2341 cggtgatgat ctttaagtcc tgtcgggttt cgccactcct gactgattca tggttgagcc
     2401 accggctccc acagatgcac cgaaaaagcg tctgtttatg tgaactcagt caggagggcg
     2461 gagcctatgg aaaaacgcca cctgcgtggc cttgccgttt tgcctcacat gttagtcccc
     2521 tgcttattca cggaatctgt gggtaacttt gcatgtgtcc gcagcgcccg ccgcagtctc
     2581 acggccggag cgtagcgacc gagtgagcga ggaggcgcaa tttccccggc acctacaaga
     2641 cggacaccgg acgcgctgat gtggcatatt gtcccctgat taagtcttta tattccctga
     2701 taataaatta ccaggatagg tgaatcatat cggtttttcg ctgaacattt tacgttaacc
     2761 tatctctgtt gcttttttct ccttacggag aaatacaggt catccccgcg agggcgtggc
     2821 tgacctcagg gggatatccc ctgcttacgc tggctggacg ccaccgacgc acggtctctc
     2881 cccctctttc tggctccgtc cggctggacg ccggccacgc cagaaattca cccggccccc
     2941 gtcaggctca cgcctgacca cccacaaaaa tccacggtgc tggacgcacc tggcgaagca
     3001 gcaaagctgc tcctgatttt gcgggtggtc agccgctcgc tatggcgaac tctgacgggg
     3061 gccggaacac cggaaaagac cgcactgggg tgccgccttt tcctctcaca cgctggggcg
     3121 tgctcgttgt tcctccgggg ctgcgccttt tccgcatggg gcggaaagag gctggcctcc
     3181 gtggtgaaag ctgaacgcaa tcaccacgga cgtgaccgcc gccgccatgc cttggggcat
     3241 gtccgcggct tgtgcagcgg gggctgcaca tcacgccggc aaaccatcgt ctgaaggaga
     3301 gagaacatgt ttaatacgga ttcgcttgcc tggaagtggc acattccgga gctggcccgg
     3361 cagatttatc cgtgggtcag ctggctgtac caggagtatt acggtctggc cggggctttc
     3421 ctagttatcg gcctgttttt cggtctggct gaactttggg ccggacggat gcgttttgtg
     3481 gggctgagtc ataaggagcg acgggagtat gccgatcgct ataagcgcga taataaacgg
     3541 ccagcgccat tttcggtgct ggcctcgctg gattcgcccg ggcggatggt cagggcacgt
     3601 cgacatgtct ggaactacgc gtactggctg accggcgcgg ccggtctggc ccttctgggg
     3661 gggctggttg tcgccgtgtt tatcgagagc tggggagaaa ccgtcctgcg tccggacctc
     3721 tacgcaaacg cagattatta cctgctgcag ccggctaacc tgttcgggat tgcctggtgc
     3781 gcgggcgggc tggctgtcgg gattgtgttg gcgcggctgc tggcgttcct gctgcttgac
     3841 ggtcattttg cggctgctga cgaggcggtg aacgcgaaac tgaatcagga gagccggcgc
     3901 agcagccagc ggacaggaga gatgaccgac gtgcgccacc tgcatttcgg ggagccggta
     3961 ccggttaatg cgctggccga tttttcctcg gagcaggccc ggcaggagca ggcggtgttt
     4021 ctgggtaagg atgagcaggg caagccggtg ctggttccgc gtgatacctg gcgcaagacc
     4081 aacattcaga tcctcggcct gcccgggagc ggcaagagcg tgatggccac caacgcgctc
     4141 attcgctgcg tacgcgattt cggggacgcg gtggtgtact tcgaccccaa aggggacgca
     4201 tgggcgccgc acgtcttccg ggcgcactgt ccggacttca ccctgctgga tctgcggccg
     4261 gggaaaccgg cgcagctgaa tctgttccgc gatctcgacc agtacgcgct gaaaaacctg
     4321 ctgattgccg ggcttaacct gggcgagacc ggcgacgtgg cggaccacta ccgcatcagc
     4381 gagcagaaag cggcgaagct gattgcggag cagtttccgc agggggcaaa cattcagcag
     4441 gtgctggcgg cggcgtacgc gctgccggag gccctgaaaa aggacgtgaa ggggttgatc
     4501 actaggctgg aaaacgtcgc tgacctgagc gtcctgcaga cggacagtgg catcgatgtg
     4561 gcggggatta tcaacggcgg cggctgcctg tacgttatcg gctcgatgga cgacgaggcg
     4621 gtgatccgtg tgcaaaaaat gctgtttgcc cgctgcgcgc aaatcatcat tgcgcgggac
     4681 gagttccggg agtggccaca cgtcagcgtg atgctcgatg aaattaaata tctgctgtcg
     4741 aagtatgtac tgaacgcact ggggacgctg cgcagccggg actgcaatct gttgctcgcg
     4801 caccagtcgc tgggcgattt cgggcagtgc gggcaggatc tgcccgctga atttgtgaaa
     4861 accacggtac tggataacac gccgatccgc tggttttacc gggcggccag cctggagtcc
     4921 gcgcagtggg cggcggggca gaccggggaa atcagggtgg acgtggagcg ccgccgtgcc
     4981 agccgggagg cggggaacgt ggagcatatc agcggggaca gcttcatcca gaaggaggcg
     5041 cggccgctgt ttgacgtgaa caccctgcaa cacctgccgg acgggttcgc ggtcatgacc
     5101 gggctgggtg tggcccggat ggcgttcagc agtccgctgc gggttgagcg ccgggaaatc
     5161 ccgttgcagc gtttcccggt gctggcgaaa accgatcccc tggcggagtt ccggcccccg
     5221 gccgacggcg gcgggccgaa agcggatgat gattttgcgg ggatttactg atggcgctgg
     5281 agctgtacaa cgtcagccac gcgaaacgac aggcgcggaa cgcggagaaa acccggctga
     5341 ccctgcgctg gttgcgggaa gagctgtgtt ccacggcgga gctggttgcg cggcggctgg
     5401 ggattgcggc ggtgcagccg gtctaccgct tcctcgacag cctggtggcg aaagggctgc
     5461 tggtccggac caaatatccg gtggacggcc gtcaggtcag cgtgtggggg ctgacgccgc
     5521 atggcgtggc gttctcgttc gacgaggacg aaccgctggc ggatgttatt ccgtttcagc
     5581 cgtcaagggt gtcggcagca catctgccgc accggctggc cgtgcaatcc ctgcgccttg
     5641 atatggaagc cagaggggcc accggctggc gcattctgca ccgtctgagt cttaaaggca
     5701 tgaaagtgcc ggacgccctg gcggagctgg acggtaaaac ggtggcgttt gaggtggagc
     5761 gcaccgtcaa gagccgtcgc cggtatcagg aagtggtgtc cgggtatctg ttcaaccgca
     5821 aagctaacgg catcgatgaa atctggtaca tctgcccgga ccgggcgacg caggtcaggg
     5881 tgcagcgggc aatcctgtcg gtggatgaaa tcgtgaaccc acagaccggc gaggcccgca
     5941 aaacggcaga gctggatcgt gaacggttgt ttgcgtgctt taaatttatg acaacggagt
     6001 gagggattat ggcgctgtac atggtattta ttgaagacgc ggaggaccgg aacggcgagc
     6061 gctgcatcat gccgaccagc gagcatctgg aagatatggt ggtgctcgcc tggcagaccg
     6121 gggcgtatgt tttctgtttt gtcgaccggg cccagcatct ggcgatgatg aaatccatcg
     6181 ggatgtatga cgagcggctc aacagcgacg aaaaagccac gtactttttc actggtaaaa
     6241 atccgcaatg ggaacggaac aaacccacag gaatgaagct gtgtgattac ctctatcgca
     6301 aggtggagcg gttcgccatc gagaacggtg tgcaggtggt tgatgccggg aagtgctcac
     6361 cggagcagat taacgcgatg attgacgtgg tgagtgagcg gcacggggaa agcgcggtga
     6421 acgagaagct gaaagcggag ctgatgcggg aatataacag ccgctatttt aacgtgccgg
     6481 tacctgaact gccggaggac aaacctgccc gccggtggtg gccgttcggc aaaaaataaa
     6541 tgccagcacc ggccatgccg gtgctgttat tcctccccga gcttatcccg catcacctgc
     6601 cagagtgttt ccgcatcctc gtgtagccgc tcgcacatgt cggccggggt atccatatcc
     6661 agctcattca gtttatcgag caatagcagc gactgctcct taataaattt agccatattg
     6721 agggctgttt tttcctgttt tgtcatgatt ctttccttcc gggcatggtg tgcgcctgtc
     6781 aggtatactg tctcaaaaat agcggggtga gacaatggcg tgggtgacgg tgagacaggc
     6841 gacggaactg acgggtaaag cccgaagttc cctgtatcgg gatatggcga aaggccgcgt
     6901 atcataccgt acggaagctg atggcggccg ggtggtggat accagcgagc ttatccgggt
     6961 gtacggtgag ttaagacagg atgagactca cgagcgggac gagttgagac tgtcgggtga
     7021 gactgaaaaa atggcctccg acgcgttgat cgcggagata aaagcactca gggaggaggt
     7081 ggccgggcta cggcaggaaa tgcagtccat gagactgctg gaacacaaac cggagacagc
     7141 agagaccccg gccggaacac cgcgccggtg gtggccgtgg ggaaaacgct gacgcgctgt
     7201 gcttgtccaa ccggcgacgg ccacgcaatg aattgcgtcc ccgtcaccgg ttattagaga
     7261 acaatatggg gattctggcg ctggccgacc acggccagaa cccggacttt tctggtctgg
     7321 tcatcaacat catagaggac atgctgtccc atcagactga tccggcgaac gtcctcgcca
     7381 tagcgtgagt ccacttcata gagtcgcggg aagtcggcca gtttgtccgc cgcagcgaga
     7441 acccggtcgg taacgttctg cgcatcccac agggatgaat tttccgcgat atagtcaaac
     7501 agcgtcgtta catcctcgat ggctccctgc ttccattcca cgtcatacgg catcgcgcag
     7561 ttcctgataa cggccatgca ggcgctggcg gagttgttcc gtggtcatac ccggacgcgt
     7621 gtcagcacgg gcggcggtca ctttggcgcg aacctgatct tcatactctg cctgggccag
     7681 ttcttcgtta gccagtcgct gcaacagcgc agctttgtcc gggccacctt ccggcagtat
     7741 gcggggcagg ctttcagcca gttcccgaag aaagttggcg ttttcgtagt gtgtagtgtt
     7801 gctcattgcg gagcctcccg ggttaatgcg gcaatatgaa ggaagtttag cagggggcgg
     7861 tctgaaagaa tatggtcgtg tcagtcaggc tgatgaagca gaaagtcggt aaaaaagggc
     7921 ttacggcatc cattttacgt caaaacatat gccatgcagt tgcgtgcata ggcatgcatt
     7981 aggataaaat ttatcgggcg cgtttccggc agttttccgg gggggttgtt gcctgtttta
     8041 tcccgtagcc gccggaaacg ccctgagccc gtctgagcgg tgcgcgtaat gacgcgttat
     8101 ggtaaatcca cttactgtct gccttcatag ccatcgagat aaacagctga aatggtgtca
     8161 gccagtagcc ttgatttttt cggtgtgagg tctttgctgc ggtaatcggt acccgcaaat
     8221 tgtgttgtgc cttggagtga gtttaaaaat tcctgactgt gaaactgctg aatgcgttgc
     8281 tgcacatcac tccgtgattt tccggtcgct ttatcctttg cgcccatatc ccagaactgc
     8341 cggaaaaaag gcaccatcat tcgtgttgtg tcagctttct gggtggaaaa attgggatca
     8401 aaaccgtcat ctgaagcata tacgtaatgc cgggtatgct gttccacgct gccctttgga
     8461 gcacaggcag tgagagttgc tgtcgctgtt atcatggcga taagacacag tttgctgccg
     8521 gaacgtctca tgagcgtctc cttaccttta attctttttt ctcattgagt tatatatccg
     8581 caggctatct tatcatcagt ttctgaccgt gttcagtgac cgaacaaccc gaaccagacc
     8641 ccccgtttct tttcctgtcc cggagggggc tttctggtat ctcatataat gatttcagta
     8701 aaacatactg aggccggaga acggcgccgt ttgtgctggt ttttgttgca tctggagggg
     8761 attgcgcatg gtgtgagtgg ctgttttttt gatcattttc acaaaaacgc aaatttacag
     8821 acttgacatg aaaaacaagg cagcgtaatt tttgtactgt atataaaacc agtggttata
     8881 tgtacagtat tttattttag tttattgttt taaaagtcaa agaggaaaag tatatgagtg
     8941 gcggagacgg acgaggtccg ggtaattcag gtctgggaca caatggtggt caggccagtg
     9001 ggaatgtgaa cggtacatca ggtaaaggtg gcccttcatc aggtggtggt acggatccaa
     9061 acagcgggcc gggctggggt acgacgcata cacctaacgg ggatattcat aactataacc
     9121 cgggggagtt tggtaacggc gggagtaaac ccggtggtaa tggcggtaac agcggcaatc
     9181 atagcgggag ctctggtggc ggacagtctt cggccaccgc gatggccttc ggtctgcctg
     9241 ccctggccac tccgggggct gaaggactgg ctttatccgt ttccggcgat gcgttgtcgg
     9301 ccgctgttgc tgatgtgctg gctgccctga aaggtccgtt taagtttggt ctgtggggga
     9361 ttgcgattta cggagtgctg ccttctgaga tagcaaaaga tgatccgaaa atgatgtcaa
     9421 aaatcgtgac gtcattgccg gcagacacgg taacggagac gccggtcagc tccctgccgc
     9481 tggaccaggc gacggtcagc gtcactaaac gtgtggcgga tattgtgaag gacgagcggc
     9541 agcatattgc ggttgtcacc ggccggccaa tgagtgttcc tgtggtggat gcgaaaccga
     9601 caaaacgtcc gggggtattc agtgtgtcga ttccgggtct cccgtctctg caggtgagcg
     9661 tacctaaagg tgttccggcc gcgaaagccc cgccaaaagg cattattgct gaaaaaggtg
     9721 attcacgtcc ggctggtttt acggccggtg gtaactcccg tgaggccgtt attcgtttcc
     9781 cgaaagagag cggacagaaa ccggtctatg tgtcggtgac ggatgttctt actccggcac
     9841 aggtaaaaca gcgtctggag gaagaaaagc gtcgccagca ggcatgggac gctgctcacc
     9901 cggaagaggg gctgaaaaga gagtatgata aagcgaaagc tgagctggat gctgaagata
     9961 aaaatattgc gaccttaaac agtcgcattg catcgacaga gaaggcgatc cccggtgcaa
    10021 gggctgctgt tcaggaagcc gataaaaagg taaaagaggc agaggcaaat aaagatgatt
    10081 ttgtgactta taacccgcct catgaatatg gctccgggtg gcaggatcag gttcgctatc
    10141 ttgataagga tattcagaat cagaatgaga aattaaaagc tgcccagaca tctttaaacg
    10201 aaatgaatga atccttatcc agggataagg ctgcgctttc cggggcgatg gagagccgga
    10261 aacaaaagga gaaaaaagcg aaggatgcag aaaataaatt aaatgaggaa aagaaaaaac
    10321 ctcgtaaggg aactaaagat tacggccatg attattttcc tgatcccaag actgaagata
    10381 ttaaggggtt gggagagttg aaagagggta aacctaaaac ccctaaacaa ggtggtggtg
    10441 gtaagcgggc ccgatggtat ggtgataaaa agcgtaaaat ttatgaatgg gattcccagc
    10501 acggtgagct tgaagggtac cgcgccagtg atggcgaaca cctcggggca ttcgatccaa
    10561 aaacgggtaa gcaggttaaa gggccggatc caaaacgaaa cattaaaaaa tatctttaag
    10621 aggtaaatat ggggcttaaa ttacatattc attggtttga taagaaaacc gaagagttta
    10681 aaggtggtga atactcaaaa gacttcggtg atgatggttc tgtcattgaa agtctgggga
    10741 tgcctttaaa ggataatatt aataatggtt ggtttgatgt tgaaaaatca tgggtttcga
    10801 tattacagcc acactttaaa aatgtaatcg atattagtaa atttgattac tttgtatcct
    10861 ttgtttaccg ggatggtaac tggtaagcaa aagttatcaa ggatgatttg aaatacagac
    10921 ttccggtgtt cagggatgaa taccggggtt tttaaataca gggaaggtat atgaaaaagg
    10981 taaaggttgt ttttcttttt atattgattt tttcaggctt tcttctggtc gcatgtcagg
    11041 caaacggcac tgttgcaaag ttagcgatga ggcagccttt tgtcttattc aaaggcctta
    11101 catttcaaaa actctgctta ccaggcgcat ttcgcccagg ggatcaccat aataaaatgc
    11161 tgaggcctgg cctttgcgta gtgcacgcat cacctcaata cctttgatgg tggcgtaagc
    11221 cgtcttcatg gatttaaatc ccagcgtggc gccgattatc cgtttcagtt tgccatgatc
    11281 gcattcaatc acgttgttcc ggtacttaat ctgtcggtgt tcaacgtcag acgggcaccg
    11341 gccttcgcgt ttgagcagag caagcgcgcg acaataggcg ggcgctttat ccgtgttgat
    11401 gaatcgcggg atctgccact tcttcacgtt gttgaggatt ttacccagaa accggtatgc
    11461 agctttgctg ttacgacggg aggagagata aaaatcgaca gtgcggcccc ggctgtcgac
    11521 ggcccggtac agatacgccc agcggccatt gaccttcacg taggtttcat ccatgtgcca
    11581 cgggcaaaga tcggaagggt tacgccagta ccagcgcagc cgtttttcca tttcaggcgc
    11641 ataacgctga acccagcggt aaatcgtgga gtgatcgaca ttcactccgc gttcagccag
    11701 catctcctgc agctcacggt aactgatgcc gtatttgcag taccagcgta cggcccacag
    11761 aatgatgtca cgctgaaaat gccggccttt gaatgggttc atgtgcagct ccatcagcaa
    11821 aaggggatga taagtttatc accaacgact atttgcaaca gtgccaggca aactatatcc
    11881 gggatgttca gggtggaacg gtggcaccat cgtcctcctc tgaactgacg gggatcgcgg
    11941 ttcagtagaa aagatcaaag gatcttcttg agatcctttt tttctgcgcg taatcttttg
    12001 ccctgtaaac gaaaaaacca cctggggagg tggtttgatc gaaggttaag tcagttgggg
    12061 aactgcttaa ccgtggtaac tggctttcgc agagcacagc aaccaaatct gtccttccag
    12121 tgtagccgga ctttggcgca cacttcaaga gcaaccgcgt gtttagctaa acaaatcctc
    12181 tgcgaactcc cagttaccaa tggctgctgc cagtggcgtt ttgcgtgctt ttccgggttg
    12241 gactcaagtg aacagttacc ggataaggcg cagcagtcgg gctgaacggg gggttcttgc
    12301 ttacagccca gcttggagcg aacgacctac accgagccga gataccagag tgtgagctat
    12361 gagaaagcgc cacacttccc gcaagggaga aaggcggaac aggtatccgg gaaacggcag
    12421 ggttggaaca ggagagcgca agagggagcg attcatcgga aacggtgatg atctttaagt
    12481 cctgtcgggt ttcgccactc ctgactgatt catggttgag ccaccggctc ccacagatgc
    12541 accgaaaaag cgtctgttta tgtgaactca gtcaggaggg cggagcctat ggaaaaacgc
    12601 cacctgcgtg gccttgccgt tttgcctcac atgttagtcc cctgcttatt cacggaatct
    12661 gtgggtaact ttgcatgtgt ccgcagcgcc cgccgcagtc tcacggccgg agcgtagcga
    12721 ccgagtgagc gaggaggcgc aatttccccg gcacctacaa gacggacacc ggacgcgctg
    12781 atgtggcata ttgtcccctg attaagtctt tatattccct gataataaat taccaggata
    12841 ggtgaatcat atcggttttt cgctgaacat tttacgttaa cctatctctg ttgctttttt
    12901 ctccttacgg agaaatacag gtcatccccg cgagggcgtg gctgacctca gggggatatc
    12961 ccctgcttac gctggctgga cgccaccgac gcacggtctc tccccctctt tctggctccg
    13021 tccggctgga cgccggccac gccagaaatt cacccggccc ccgtcaggct cacgcctgac
    13081 gggggccggg tgaatttctg gcgtggccgg cgtccagccg gacggagcca gaaagagggg
    13141 gagagaccgt gcgtcggtgg cgtccagcca gcgtaagcag gggatatccc cctgaggtca
    13201 gccacgccct cgcggggatg acctgtattt ctccgtaagg agaaaaaagc aacagagata
    13261 ggttaacgta aaatgttcag cgaaaaaccg atatgattca cctatcctgg taatttatta
    13321 tcagggaata taaagactta atcaggggac aatatgccac atcagcgcgt ccggtgtccg
    13381 tcttgtaggt gccggggaaa ttgcgcctcc tcgctcactc ggtcgctacg ctccggccgt
    13441 gagactgcgg cgggcgctgc ggacacatgc aaagttaccc acagattccg tgaataagca
    13501 ggggactaac atgtgaggca aaacggcaag gccacgcagg tggcgttttt ccataggctc
    13561 cgccctcctg actgagttca cataaacaga cgctttttcg gtgcatctgt gggagccggt
    13621 ggctcaacca tgaatcagtc aggagtggcg aaacccgaca ggacttaaag atcatcaccg
    13681 tttccgatga atcgctccct cttgcgctct cctgttccaa ccctgccgtt tcccggatac
    13741 ctgttccgcc tttctccctt gcgggaagtg tggcgctttc tcatagctca cactctggta
    13801 tctcggctcg gtgtaggtcg ttcgctccaa gctgggctgt aagcaagaac cccccgttca
    13861 gcccgactgc tgcgccttat ccggtaactg ttcacttgag tccaacccgg aaaagcacgc
    13921 aaaacgccac tggcagcagc cattggtaac tgggagttcg cagaggattt gtttagctaa
    13981 acacgcggtt gctcttgaag tgtgcgccaa agtccggcta cactggaagg acagatttgg
    14041 ttgctgtgct ctgcgaaagc cagttaccac ggttaagcag ttccccaact gacttaacct
    14101 tcgatcaaac cacctcccca ggtggttttt tcgtttacag ggcaaaagat tacgcgcaga
    14161 aaaaaaggat ctcaagaaga tcctttgatc ttttctactg aaccgcgatc cccgtcagtt
    14221 cagaggagga cgatggtgcc accgttccac cctgaacatc ccggatatag tttgcctggc
    14281 actgttgcaa atagtcgttg gtgataaact tatcatccac ttttgctgat ggagctgcac
    14341 atgaacccat tcaaaggccg gcattttcag cgtgacatca ttctgtgggc cgtacgctgg
    14401 tactgcaaat acgtcatcag ttaccgtgag ctgcaggaga tgctggctga acgcggagtg
    14461 aatgtcgatc actccacgat ttaccgctgg tttcagcgtt atgcgcctga aatggaaaaa
    14521 cggctgcgct ggtactggcg taacccttcc gatctttgcc cgtggcacat ggatgaaacc
    14581 tacgtgaagg tcaatggccg ctgggcgtat ctgtaccggg ccgtcgacag ccggggccgc
    14641 actgtcgatt tttatctctc ctcccgtcgt aacagcaaag ctgcataccg gtttctgggt
    14701 aaaatcctca acaacgtgaa gaagtggcag atcccgcgat tcatcaacac ggataaagcg
    14761 cccgcctatg gtcgcgcgct tgctctgctc aaacgcgaag gccggtgccc gtctgacgtt
    14821 gaacaccgac agattaagta ccggaacaac gtgattgaat gcgatcatgg caaactgaaa
    14881 cggataatcg gcgccacgct gggatttaaa tccatgaaga cgacttacgc caccatcaaa
    14941 ggcattgagg tgatgcgtgc actacgcaaa ggccatgcct cagcatttta ttatggtgat
    15001 cccctgggcg aaatgcgcct ggtaagcaga gtttttgaaa tgtaaggcct ttgaataaga
    15061 caaaaggctg cctcatcgct aactttgcaa cagtgccgtt tgcctgacat gcgaccagaa
    15121 gaaagcctga aaaaatcaat ataaaaagaa aaacaacctt tacctttttc atataccttc
    15181 cctgtattta aaaaccccgg tattcatccc tgaacaccgg aagtctgtat ttcaaatcat
    15241 ccttgataac ttttgcttac cagttaccat cccggtaaac aaaggataca aagtaatcaa
    15301 atttactaat atcgattaca tttttaaagt gtggctgtaa tatcgaaacc catgattttt
    15361 caacatcaaa ccaaccatta ttaatattat cctttaaagg catccccaga ctttcaatga
    15421 cagaaccatc atcaccgaag tcttttgagt attcaccacc tttaaactct tcggttttct
    15481 tatcaaacca atgaatatgt aatttaagcc ccatatttac ctcttaaaga tattttttaa
    15541 tgtttcgttt tggatccggc cctttaacct gcttacccgt ttttggatcg aatgccccga
    15601 ggtgttcgcc atcactggcg cggtaccctt caagctcacc gtgctgggaa tcccattcat
    15661 aaattttacg ctttttatca ccataccatc gggcccgctt accaccacca ccttgtttag
    15721 gggttttagg tttaccctct ttcaactctc ccaacccctt aatatcttca gtcttgggat
    15781 caggaaaata atcatggccg taatctttag ttcccttacg aggttttttc ttttcctcat
    15841 ttaatttatt ttctgcatcc ttcgcttttt tctccttttg tttccggctc tccatcgccc
    15901 cggaaagcgc agccttatcc ctggataagg attcattcat ttcgtttaaa gatgtctggg
    15961 cagcttttaa tttctcattc tgattctgaa tatccttatc aagatagcga acctgatcct
    16021 gccacccgga gccatattca tgaggcgggt tataagtcac aaaatcatct ttatttgcct
    16081 ctgcctcttt taccttttta tcggcttcct gaacagcagc ccttgcaccg gggatcgcct
    16141 tctctgtcga tgcaatgcga ctgtttaagg tcgcaatatt tttatcttca gcatccagct
    16201 cagctttcgc tttatcatac tctcttttca gcccctcttc cgggtgagca gcgtcccatg
    16261 cctgctggcg acgcttttct tcctccagac gctgttttac ctgtgccgga gtaagaacat
    16321 ccgtcaccga cacatagacc ggtttctgtc cgctctcttt cgggaaacga ataacggcct
    16381 cacgggagtt accaccggcc gtaaaaccag ccggacgtga atcacctttt tcagcaataa
    16441 tgccttttgg cggggctttc gcggccggaa cacctttagg tacgctcacc tgcagagacg
    16501 ggagacccgg aatcgacaca ctgaataccc ccggacgttt tgtcggtttc gcatccacca
    16561 caggaacact cattggccgg ccggtgacaa ccgcaatatg ctgccgctcg tccttcacaa
    16621 tatccgccac acgtttagtg acgctgaccg tcgcctggtc cagcggcagg gagctgaccg
    16681 gcgtctccgt taccgtgtct gccggcaatg acgtcacgat ttttgacatc attttcggat
    16741 catcttttgc tatctcagaa ggcagcactc cgtaaatcgc aatcccccac agaccaaact
    16801 taaacggacc tttcagggca gccagcacat cagcaacagc ggccgacaac gcatcgccgg
    16861 aaacggataa agccagtcct tcagcccccg gagtggccag ggcaggcaga ccgaaggcca
    16921 tcgcggtggc cgaagactgt ccgccaccag agctcccgct atgattgccg ctgttaccgc
    16981 cattaccacc gggtttactc ccgccgttac caaactcccc cgggttatag ttatgaatat
    17041 ccccgttagg tgtatgcgtc gtaccccagc ccggcccgct gtttggatcc gtaccaccac
    17101 ctgatgaagg gccaccttta cctgatgtac cgttcacatt cccactggcc tgaccaccat
    17161 tgtgtcccag acctgaatta cccggacctc gtccgtctcc gccactcata tacttttcct
    17221 ctttgacttt taaaacaata aactaaaata aaatactgta catataacca ctggttttat
    17281 atacagtaca aaaattacgc tgccttgttt ttcatgtcaa gtctgtaaat ttgcgttttt
    17341 gtgaaaatga tcaaaaaaac agccactcac accatgcgca atcccctcca gatgcaacaa
    17401 aaaccagcac aaacggcgcc gttctccggc ctcagtatgt tttactgaaa tcattatatg
    17461 agataccaga aagccccctc cgggacagga aaagaaacgg ggggtctggt tcgggttgtt
    17521 cggtcactga acacggtcag aaactgatga taagatagcc tgcggatata taactcaatg
    17581 agaaaaaaga attaaaggta aggagacgct catgagacgt tccggcagca aactgtgtct
    17641 tatcgccatg ataacagcga cagcaactct cactgcctgt gctccaaagg gcagcgtgga
    17701 acagcatacc cggcattacg tatatgcttc agatgacggt tttgatccca atttttccac
    17761 ccagaaagct gacacaacac gaatgatggt gccttttttc cggcagttct gggatatggg
    17821 cgcaaaggat aaagcgaccg gaaaatcacg gagtgatgtg cagcaacgca ttcagcagtt
    17881 tcacagtcag gaatttttaa actcactcca aggcacaaca caatttgcgg gtaccgatta
    17941 ccgcagcaaa gacctcacac cgaaaaaatc aaggctactg gctgacacca tttcagctgt
    18001 ttatctcgat ggctatgaag gcagacagta agtggattta ccataacgcg tcattacgcg
    18061 caccgctcag acgggctcag ggcgtttccg gcggctacgg gataaaacag gcaacaaccc
    18121 ccccggaaaa ctgccggaaa cgcgcccgat aaattttatc ctaatgcatg cctatgcacg
    18181 caactgcatg gcatatgttt tgacgtaaaa tggatgccgt aagccctttt ttaccgactt
    18241 tctgcttcat cagcctgact gacacgacca tattctttca gaccgccccc tgctaaactt
    18301 ccttcatatt gccgcattaa cccgggaggc tccgcaatga gcaacactac acactacgaa
    18361 aacgccaact ttcttcggga actggctgaa agcctgcccc gcatactgcc ggaaggtggc
    18421 ccggacaaag ctgcgctgtt gcagcgactg gctaacgaag aactggccca ggcagagtat
    18481 gaagatcagg ttcgcgccaa agtgaccgcc gcccgtgctg acacgcgtcc gggtatgacc
    18541 acggaacaac tccgccagcg cctgcatggc cgttatcagg aactgcgcga tgccgtatga
    18601 cgtggaatgg aagcagggag ccatcgagga tgtaacgacg ctgtttgact atatcgcgga
    18661 aaattcatcc ctgtgggatg cgcagaacgt taccgaccgg gttctcgctg cggcggacaa
    18721 actggccgac ttcccgcgac tctatgaagt ggactcacgc tatggcgagg acgttcgccg
    18781 gatcagtctg atgggacagc atgtcctcta tgatgttgat gaccagacca gaaaagtccg
    18841 ggttctggcc gtggtcggcc agcgccagaa tccccatatt gttctctaat aaccggtgac
    18901 ggggacgcaa ttcattgcgt ggccgtcgcc ggttggacaa gcacagcgcg tcagcgtttt
    18961 ccccacggcc accaccggcg cggtgttccg gccggggtct ctgctgtctc cggtttgtgt
    19021 tccagcagtc tcatggactg catttcctgc cgtagcccgg ccacctcctc cctgagtgct
    19081 tttatctccg cgatcaacgc gtcggaggcc attttttcag tctcacccga cagtctcaac
    19141 tcgtcccgct cgtgagtctc atcctgtctt aactcaccgt acacccggat aagctcgctg
    19201 gtatccacca cccggccgcc atcagcttcc gtacggtatg atacgcggcc tttcgccata
    19261 tcccgataca gggaacttcg ggctttaccc gtcagttccg tcgcctgtct caccgtcacc
    19321 cacgccattg tctcaccccg ctatttttga gacagtatac ctgacaggcg cacaccatgc
    19381 ccggaaggaa agaatcatga caaaacagga aaaaacagcc ctcaatatgg ctaaatttat
    19441 taaggagcag tcgctgctat tgctcgataa actgaatgag ctggatatgg ataccccggc
    19501 cgacatgtgc gagcggctac acgaggatgc ggaaacactc tggcaggtga tgcgggataa
    19561 gctcggggag gaataacagc accggcatgg ccggtgctgg catttatttt ttgccgaacg
    19621 gccaccaccg gcgggcaggt ttgtcctccg gcagttcagg taccggcacg ttaaaatagc
    19681 ggctgttata ttcccgcatc agctccgctt tcagcttctc gttcaccgcg ctttccccgt
    19741 gccgctcact caccacgtca atcatcgcgt taatctgctc cggtgagcac ttcccggcat
    19801 caaccacctg cacaccgttc tcgatggcga accgctccac cttgcgatag aggtaatcac
    19861 acagcttcat tcctgtgggt ttgttccgtt cccattgcgg atttttacca gtgaaaaagt
    19921 acgtggcttt ttcgtcgctg ttgagccgct cgtcatacat cccgatggat ttcatcatcg
    19981 ccagatgctg ggcccggtcg acaaaacaga aaacatacgc cccggtctgc caggcgagca
    20041 ccaccatatc ttccagatgc tcgctggtcg gcatgatgca gcgctcgccg ttccggtcct
    20101 ccgcgtcttc aataaatacc atgtacagcg ccataatccc tcactccgtt gtcataaatt
    20161 taaagcacgc aaacaaccgt tcacgatcca gctctgccgt tttgcgggcc tcgccggtct
    20221 gtgggttcac gatttcatcc accgacagga ttgcccgctg caccctgacc tgcgtcgccc
    20281 ggtccgggca gatgtaccag atttcatcga tgccgttagc tttgcggttg aacagatacc
    20341 cggacaccac ttcctgatac cggcgacggc tcttgacggt gcgctccacc tcaaacgcca
    20401 ccgttttacc gtccagctcc gccagggcgt ccggcacttt catgccttta agactcagac
    20461 ggtgcagaat gcgccagccg gtggcccctc tggcttccat atcaaggcgc agggattgca
    20521 cggccagccg gtgcggcaga tgtgctgccg acacccttga cggctgaaac ggaataacat
    20581 ccgccagcgg ttcgtcctcg tcgaacgaga acgccacgcc atgcggcgtc agcccccaca
    20641 cgctgacctg acggccgtcc accggatatt tggtccggac cagcagccct ttcgccacca
    20701 ggctgtcgag gaagcggtag accggctgca ccgccgcaat ccccagccgc cgcgcaacca
    20761 gctccgccgt ggaacacagc tcttcccgca accagcgcag ggtcagccgg gttttctccg
    20821 cgttccgcgc ctgtcgtttc gcgtggctga cgttgtacag ctccagcgcc atcagtaaat
    20881 ccccgcaaaa tcatcatccg ctttcggccc gccgccgtcg gccgggggcc ggaactccgc
    20941 caggggatcg gttttcgcca gcaccgggaa acgctgcaac gggatttccc ggcgctcaac
    21001 ccgcagcgga ctgctgaacg ccatccgggc cacacccagc ccggtcatga ccgcgaaccc
    21061 gtccggcagg tgttgcaggg tgttcacgtc aaacagcggc cgcgcctcct tctggatgaa
    21121 gctgtccccg ctgatatgct ccacgttccc cgcctcccgg ctggcacggc ggcgctccac
    21181 gtccaccctg atttccccgg tctgccccgc cgcccactgc gcggactcca ggctggccgc
    21241 ccggtaaaac cagcggatcg gcgtgttatc cagtaccgtg gttttcacaa attcagcggg
    21301 cagatcctgc ccgcactgcc cgaaatcgcc cagcgactgg tgcgcgagca acagattgca
    21361 gtcccggctg cgcagcgtcc ccagtgcgtt cagtacatac ttcgacagca gatatttaat
    21421 ttcatcgagc atcacgctga cgtgtggcca ctcccggaac tcgtcccgcg caatgatgat
    21481 ttgcgcgcag cgggcaaaca gcattttttg cacacggatc accgcctcgt cgtccatcga
    21541 gccgataacg tacaggcagc cgccgccgtt gataatcccc gccacatcga tgccactgtc
    21601 cgtctgcagg acgctcaggt cagcgacgtt ttccagccta gtgatcaacc ccttcacgtc
    21661 ctttttcagg gcctccggca gcgcgtacgc cgccgccagc acctgctgaa tgtttgcccc
    21721 ctgcggaaac tgctccgcaa tcagcttcgc cgctttctgc tcgctgatgc ggtagtggtc
    21781 cgccacgtcg ccggtctcgc ccaggttaag cccggcaatc agcaggtttt tcagcgcgta
    21841 ctggtcgaga tcgcggaaca gattcagctg cgccggtttc cccggccgca gatccagcag
    21901 ggtgaagtcc ggacagtgcg cccggaagac gtgcggcgcc catgcgtccc ctttggggtc
    21961 gaagtacacc accgcgtccc cgaaatcgcg tacgcagcga atgagcgcgt tggtggccat
    22021 cacgctcttg ccgctcccgg gcaggccgag gatctgaatg ttggtcttgc gccaggtatc
    22081 acgcggaacc agcaccggct tgccctgctc atccttaccc agaaacaccg cctgctcctg
    22141 ccgggcctgc tccgaggaaa aatcggccag cgcattaacc ggtaccggct ccccgaaatg
    22201 caggtggcgc acgtcggtca tctctcctgt ccgctggctg ctgcgccggc tctcctgatt
    22261 cagtttcgcg ttcaccgcct cgtcagcagc cgcaaaatga ccgtcaagca gcaggaacgc
    22321 cagcagccgc gccaacacaa tcccgacagc cagcccgccc gcgcaccagg caatcccgaa
    22381 caggttagcc ggctgcagca ggtaataatc tgcgtttgcg tagaggtccg gacgcaggac
    22441 ggtttctccc cagctctcga taaacacggc gacaaccagc ccccccagaa gggccagacc
    22501 ggccgcgccg gtcagccagt acgcgtagtt ccagacatgt cgacgtgccc tgaccatccg
    22561 cccgggcgaa tccagcgagg ccagcaccga aaatggcgct ggccgtttat tatcgcgctt
    22621 atagcgatcg gcatactccc gtcgctcctt atgactcagc cccacaaaac gcatccgtcc
    22681 ggcccaaagt tcagccagac cgaaaaacag gccgataact aggaaagccc cggccagacc
    22741 gtaatactcc tggtacagcc agctgaccca cggataaatc tgccgggcca gctccggaat
    22801 gtgccacttc caggcaagcg aatccgtatt aaacatgttc tctctccttc agacgatggt
    22861 ttgccggcgt gatgtgcagc ccccgctgca caagccgcgg acatgcccca aggcatggcg
    22921 gcggcggtca cgtccgtggt gattgcgttc agctttcacc acggaggcca gcctctttcc
    22981 gccccatgcg gaaaaggcgc agccccggag gaacaacgag cacgccccag cgtgtgagag
    23041 gaaaaggcgg caccccagtg cggtcttttc cggtgttccg gcccccgtca gagttcgcca
    23101 tagcgagcgg ctgaccaccc gcaaaatcag gagcagcttt gctgcttcgc caggtgcgtc
    23161 cagcaccgtg gatttttgtg ggtgg
//
