LOCUS       NZ_CP032199             9294 bp    DNA     circular CON 26-NOV-2023
DEFINITION  Klebsiella pneumoniae strain AR_0097 plasmid unnamed5, complete
            sequence.
ACCESSION   NZ_CP032199
VERSION     NZ_CP032199.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04014938
            Assembly: GCF_003571645.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9294)
  AUTHORS   Conlan,S., Thomas,P.J., Mullikin,J., Frank,K.M. and Segre,J.A.
  TITLE     Whole genome sequencing of Klebsiella pneumoniae AR_0097
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9294)
  AUTHORS   Segre,J.A. and Mullikin,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2018) NIH Intramural Sequencing Center, 5625
            Fishers Lane, Rockville, MD 20852, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: canu v. 1.6
            Genome Coverage                   :: 161x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/26/2023 02:25:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,696
            CDSs (total)                      :: 5,573
            Genes (coding)                    :: 5,395
            CDSs (with protein)               :: 5,395
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 178
            CDSs (without protein)            :: 178
            Pseudo Genes (ambiguous residues) :: 0 of 178
            Pseudo Genes (frameshifted)       :: 81 of 178
            Pseudo Genes (incomplete)         :: 89 of 178
            Pseudo Genes (internal stop)      :: 26 of 178
            Pseudo Genes (multiple problems)  :: 18 of 178
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032199.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="AR_0097"
                     /db_xref="taxon:573"
                     /plasmid="unnamed5"
     gene            complement(join(9091..9294,1..174))
                     /locus_tag="AM476_RS02360"
                     /old_locus_tag="AM476_02365"
     CDS             complement(join(9091..9294,1..174))
                     /locus_tag="AM476_RS02360"
                     /old_locus_tag="AM476_02365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            243..422
                     /locus_tag="AM476_RS02365"
                     /old_locus_tag="AM476_02370"
     CDS             243..422
                     /locus_tag="AM476_RS02365"
                     /old_locus_tag="AM476_02370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(450..980)
                     /locus_tag="AM476_RS02370"
                     /old_locus_tag="AM476_02375"
     CDS             complement(450..980)
                     /locus_tag="AM476_RS02370"
                     /old_locus_tag="AM476_02375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(987..1718)
                     /locus_tag="AM476_RS02375"
                     /old_locus_tag="AM476_02380"
     CDS             complement(987..1718)
                     /locus_tag="AM476_RS02375"
                     /old_locus_tag="AM476_02380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(1718..3682)
                     /locus_tag="AM476_RS02380"
                     /old_locus_tag="AM476_02385"
     CDS             complement(1718..3682)
                     /locus_tag="AM476_RS02380"
                     /old_locus_tag="AM476_02385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_119179546.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGATGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(5163..5312)
                     /locus_tag="AM476_RS02390"
                     /old_locus_tag="AM476_02395"
     CDS             complement(5163..5312)
                     /locus_tag="AM476_RS02390"
                     /old_locus_tag="AM476_02395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(5397..5654)
                     /locus_tag="AM476_RS02395"
                     /old_locus_tag="AM476_02400"
     CDS             complement(5397..5654)
                     /locus_tag="AM476_RS02395"
                     /old_locus_tag="AM476_02400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(5664..7349)
                     /locus_tag="AM476_RS02400"
                     /old_locus_tag="AM476_02405"
     CDS             complement(5664..7349)
                     /locus_tag="AM476_RS02400"
                     /old_locus_tag="AM476_02405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            7752..8171
                     /locus_tag="AM476_RS02410"
                     /old_locus_tag="AM476_02415"
     CDS             7752..8171
                     /locus_tag="AM476_RS02410"
                     /old_locus_tag="AM476_02415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            8477..8740
                     /locus_tag="AM476_RS02415"
                     /old_locus_tag="AM476_02420"
     CDS             8477..8740
                     /locus_tag="AM476_RS02415"
                     /old_locus_tag="AM476_02420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            8730..9029
                     /locus_tag="AM476_RS02420"
                     /old_locus_tag="AM476_02425"
     CDS             8730..9029
                     /locus_tag="AM476_RS02420"
                     /old_locus_tag="AM476_02425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     BGC             664..9294
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          4482..5060
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(991..1718)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 agtctcatcc tgtcttaact caccgtacac ccggataagc tcgctggtat ccaccacccg
       61 gccgccatca gcttccgtac ggtatgatac gcggcctttc gccatatccc gatacaggga
      121 acttcgggct ttacccgtca gttccgtcgc ctgtctcacc gtcacccacg ccattgtctc
      181 accccgctat ttttgagaca gtatacctga caggcgcaca ccatgcccgg aaggaaagaa
      241 tcatgacaaa acaggaaaaa acagccctca atatggctaa atttattaag gagcagtcgc
      301 tgctattgct cgataaactg aatgagctgg atatggatac cccggccgac atgtgcgagc
      361 ggctacacga ggatgcggaa acactctggc aggtgatgcg ggataagctc ggggaggaat
      421 aacagcaccg gcatggccgg tgctggcatt tattttttgc cgaacggcca ccaccggcgg
      481 gcaggtttgt cctccggcag ttcaggtacc ggcacgttaa aatagcggct gttatattcc
      541 cgcatcagct ccgctttcag cttctcgttc accgcgcttt ccccgtgccg ctcactcacc
      601 acgtcaatca tcgcgttaat ctgctccggt gagcacttcc cggcatcaac cacctgcaca
      661 ccgttctcga tggcgaaccg ctccaccttg cgatagaggt aatcacacag cttcattcct
      721 gtgggtttgt tccgttccca ttgcggattt ttaccagtga aaaagtacgt ggctttttcg
      781 tcgctgttga gccgctcgtc atacatcccg atggatttca tcatcgccag atgctgggcc
      841 cggtcgacaa aacagaaaac atacgccccg gtctgccagg cgagcaccac catatcttcc
      901 agatgctcgc tggtcggcat gatgcagcgc tcgccgttcc ggtcctccgc gtcttcaata
      961 aataccatgt acagcgccat aatccctcac tccgttgtca taaatttaaa gcacgcaaac
     1021 aaccgttcac gatccagctc tgccgttttg cgggcctcgc cggtctgtgg gttcacgatt
     1081 tcatccaccg acaggattgc ccgctgcacc ctgacctgcg tcgcccggtc cgggcagatg
     1141 taccagattt catcgatgcc gttagctttg cggttgaaca gatacccgga caccacttcc
     1201 tgataccggc gacggctctt gacggtgcgc tccacctcaa acgccaccgt tttaccgtcc
     1261 agctccgcca gggcgtccgg cactttcatg cctttaagac tcagacggtg cagaatgcgc
     1321 cagccggtgg cccctctggc ttccatatca aggcgcaggg attgcacggc cagccggtgc
     1381 ggcagatgtg ctgccgacac ccttgacggc tgaaacggaa taacatccgc cagcggttcg
     1441 tcctcgtcga acgagaacgc cacgccatgc ggcgtcagcc cccacacgct gacctgacgg
     1501 ccgtccaccg gatatttggt ccggaccagc agccctttcg ccaccaggct gtcgaggaag
     1561 cggtagaccg gctgcaccgc cgcaatcccc agccgccgcg caaccagctc cgccgtggaa
     1621 cacagctctt cccgcaacca gcgcagggtc agccgggttt tctccgcgtt ccgcgcctgt
     1681 cgtttcgcgt ggctgacgtt gtacagctcc agcgccatca gtaaatcccc gcaaaatcat
     1741 catccgcttt cggcccgccg ccgtcggccg ggggccggaa ctccgccagg ggatcggttt
     1801 tcgccagcac cgggaaacgc tgcaacggga tttcccggcg ctcaacccgc agcggactgc
     1861 tgaacgccat ccgggccaca cccagcccgg tcatgaccgc gaacccgtcc ggcaggtgtt
     1921 gcagggtgtt cacgtcaaac agcggccgcg cctccttctg gatgaagctg tccccgctga
     1981 tatgctccac gttccccgcc tcccggctgg cacggcggcg ctccacgtcc accctgattt
     2041 ccccggtctg ccccgccgcc cactgcgcgg actccaggct ggccgcccgg taaaaccagc
     2101 ggatcggcgt gttatccagt accgtggttt tcacaaattc agcgggcaga tcctgcccgc
     2161 actgcccgaa atcgcccagc gactggtgcg cgagcaacag attgcagtcc cggctgcgca
     2221 gcgtccccag tgcgttcagt acatacttcg acagcagata tttaatttca tcgagcatca
     2281 cgctgacgtg tggccactcc cggaactcgt cccgcgcaat gatgatttgc gcgcagcggg
     2341 caaacagcat tttttgcaca cggatcaccg cctcgtcgtc catcgagccg ataacgtaca
     2401 ggcagccgcc gccgttgata atccccgcca catcgatgcc actgtccgtc tgcaggacgc
     2461 tcaggtcagc gacgttttcc agcctagtga tcaacccctt cacgtccttt ttcagggcct
     2521 ccggcagcgc gtacgccgcc gccagcacct gctgaatgtt tgccccctgc ggaaactgct
     2581 ccgcaatcag cttcgccgct ttctgctcgc tgatgcggta gtggtccgcc acgtcgccgg
     2641 tctcgcccag gttaagcccg gcaatcagca ggtttttcag cgcgtactgg tcgagatcgc
     2701 ggaacagatt cagctgcgcc ggtttccccg gccgcagatc cagcagggtg aagtccggac
     2761 agtgcgcccg gaagacgtgc ggcgcccatg cgtccccttt ggggtcgaag tacaccaccg
     2821 cgtccccgaa atcgcgtacg cagcgaatga gcgcgttggt ggccatcacg ctcttgccgc
     2881 tcccgggcag gccgaggatc tgaatgttgg tcttgcgcca ggtatcacgc ggaaccagca
     2941 ccggcttgcc ctgctcatcc ttacccagaa acaccgcctg ctcctgccgg gcctgctccg
     3001 aggaaaaatc ggccagcgca ttaaccggta ccggctcccc gaaatgcagg tggcgcacgt
     3061 cggtcatctc tcctgtccgc tggctgctgc gccggctctc ctgattcagt ttcgcgttca
     3121 ccgcctcgtc agcagccgca aaatgaccgt caagcagcag gaacgccagc agccgcgcca
     3181 acacaatccc gacagccagc ccgcccgcgc accaggcaat cccgaacagg ttagccggct
     3241 gcagcaggta ataatctgcg tttgcgtaga ggtccggacg caggacggtt tctccccagc
     3301 tctcgataaa cacggcgaca accagccccc ccagaagggc cagaccggtc gcgccggtca
     3361 gccagtacgc gtagttccag acatgtcgac gtgccctgac catccgcccg ggcgaatcca
     3421 gcgaggccag caccgaaaat ggcgctggcc gtttattatc gcgcttatag cgatcggcat
     3481 actcccgtcg ctccttatga ctcagcccca caaaacgcat ccgtccggcc caaagttcag
     3541 ccagaccgaa aaacaggccg ataactagga aagccccggc cagaccgtaa tactcctggt
     3601 acagccagct gacccacgga taaatctgcc gggccagctc cggaatgtgc cacttccagg
     3661 caagcgaatc cgtattaaac atgttctctc tccttcagac gatggtttgc cggcgtgatg
     3721 tgcagccccc gctgcacaag ccgcggacat gccccaaggc atggcggcgg cggtcacgtc
     3781 cgtggtgatt gcgttcagct ttcaccacgg aggccagcct ctttccgccc catgcggaaa
     3841 aggcgcagcc ccggaggaac aacgagcacg ccccagcgtg tgagaggaaa aggcggcacc
     3901 ccagtgcggt cttttccggt gttccggccc ccgccagagt tcgccatagc gagcggctga
     3961 ccacccgcaa aatcaggagc agctttgctg cttcgccagg tgcgtccagc accgtggatt
     4021 tttgtgggtg gtcaggcgtg agcctgacgg gggccgggtg aatttctggc gtggccggcg
     4081 tccagccgga cggagccaga aagaggggga gagaccgtgc gtcggtggcg tccagccagc
     4141 gtaagcaggg gatatccccc tgaggtcagc cacgccctcg cggggatgac ctgtatttct
     4201 ccgtaaggag aaaaaagcaa cagagatagg ttaacgtaaa atgttcagcg aaaaaccgat
     4261 atgattcacc tatcctggta atttattatc agggaatata aagacttaat caggggacaa
     4321 tatgccacat cagcgcgtcc ggtgtccgtc ttgtaggtgc cggggaaatt gcgcctcctc
     4381 gctcactcgg tcgctacgct ccggccgtga gactgcggcg ggcgctgcgg acacatgcaa
     4441 agttacccac agattccgtg aataagcagg ggactaacat gtgaggcaaa acggcaaggc
     4501 cacgcaggtg gcgtttttcc ataggctccg ccctcctgac tgagttcaca taaacagacg
     4561 ctttttcggt gcatctgtgg gagccggtgg ctcaaccatg aatcagtcag gagtggcgaa
     4621 acccgacagg acttaaagat catcaccgtt tccgatgaat cgctccctct tgcgctctcc
     4681 tgttccaacc ctgccgtttc ccggatacct gttccgcctt tctcccttgc gggaagtgtg
     4741 gcgctttctc atagctcaca ctctggtatc tcggctcggt gtaggtcgtt cgctccaagc
     4801 tgggctgtaa gcaagaaccc cccgttcagc ccgactgctg cgccttatcc ggtaactgtt
     4861 cacttgagtc caacccggaa aagcacgcaa aacgccactg gcagcagcca ttggtaactg
     4921 ggagttcgca gaggatttgt ttagctaaac acgcggttgc tcttgaagtg tgcgccaaag
     4981 tccggctaca ctggaaggac agatttggtt gctgtgctct gcgaaagcca gttaccacgg
     5041 ttaagcagtt ccccaactga cttaaccttc gatcaaacca cctccccagg tggttttttc
     5101 gtttacaggg caaaagatta cgcgcagaaa aaaaggatct caagaagatc ctttgatctt
     5161 ttctactgaa ccgcgatccc cgtcagttca gaggaggacg atggtgccac cgttccaccc
     5221 tgaacatccc ggatatagtt tgcctgacat gcgaccagaa gaaagcctga aaaaatcaat
     5281 ataaaaagaa aaacaacctt tacctttttc atataccttc cctgtattta aaaaccccgg
     5341 tattcatccc tgaacaccgg aagtctgtat ttcaaatcat ccttgataac ttttgcttac
     5401 cagttaccat cccggtaaac aaaggataca aagtaatcaa atttactaat atcgattaca
     5461 tttttaaagt gtggctgtaa tatcgaaacc catgattttt caacatcaaa ccaaccatta
     5521 ttaatattat cctttaaagg catccccaga ctttcaatga cagaaccatc atcaccgaag
     5581 tcttttgagt attcaccacc tttaaactct tcggttttct tatcaaacca atgaatatgt
     5641 aatttaagcc ccatatttac ctcttaaaga tattttttaa tgtttcgttt tggatccggc
     5701 cctttaacct gcttacccgt ttttggatcg aatgccccga ggtgttcgcc atcactggcg
     5761 cggtaccctt caagctcacc gtgctgggaa tcccattcat aaattttacg ctttttatca
     5821 ccataccatc gggcccgctt accaccacca ccttgtttag gggttttagg tttaccctct
     5881 ttcaactctc ccaacccctt aatatcttca gtcttgggat caggaaaata atcatggccg
     5941 taatctttag ttcccttacg aggttttttc ttttcctcat ttaatttatt ttctgcatcc
     6001 ttcgcttttt tctccttttg tttccggctc tccatcgccc cggaaagcgc agccttatcc
     6061 ctggataagg attcattcat ttcgtttaaa gatgtctggg cagcttttaa tttctcattc
     6121 tgattctgaa tatccttatc aagatagcga acctgatcct gccacccgga gccatattca
     6181 tgaggcgggt tataagtcac aaaatcatct ttatttgcct ctgcctcttt taccttttta
     6241 tcggcttcct gaacagcagc ccttgcaccg gggatcgcct tctctgtcga tgcaatgcga
     6301 ctgtttaagg tcgcaatatt tttatcttca gcatccagct cagctttcgc tttatcatac
     6361 tctcttttca gcccctcttc cgggtgagca gcgtcccatg cctgctggcg acgcttttct
     6421 tcctccagac gctgttttac ctgtgccgga gtaagaacat ccgtcaccga cacatagacc
     6481 ggtttctgtc cgctctcttt cgggaaacga ataacggctt cacgggagtt accaccggcc
     6541 gtaaaaccag ccggacgtga atcacctttt tcagcaataa tgccttttgg cggggctttc
     6601 gcggccggaa cacctttagg tacgctcacc tgcagagacg ggagacccgg aatcgacaca
     6661 ctgaataccc ccggacgttt tgtcggtttc gcatccacca caggaacact cattggccgg
     6721 ccggtgacaa ccgcaatatg ctgccgctcg tccttcacaa tatccgccac acgtttagtg
     6781 acgctgaccg tcgcctggtc cagcggcagg gagctgaccg gcgtctccgt taccgtgtct
     6841 gccggcaatg acgtcacgat ttttgacatc attttcggat catcttttgc tatctcagaa
     6901 ggcagcactc cgtaaatcgc aatcccccac agaccaaact taaacggacc tttcagggca
     6961 gccagcacat cagcaacagc ggccgacaac gcatcgccgg aaacggataa agccagtcct
     7021 tcagcccccg gagtggccaa ggcaggcaga ccgaaggcca tcgcggtggc cgaagactgt
     7081 ccgccaccag agctcccgct atgattgccg ctgttaccgc cattaccacc gggtttactc
     7141 ccgccgttac caaactcccc cgggttatag ttatgaatat ccccgttagg tgtatgcgtc
     7201 gtaccccagc ccggcccgct gtttggatcc gtaccaccac ctgatgaagg gccaccttta
     7261 cctgatgtac cgttcacatt cccactggcc tgaccaccat tgtgtcccag acctgaatta
     7321 cccggacctc gtccgtctcc gccactcata tacttttcct ctttgacttt taaaacaata
     7381 aactaaaata aaatactgta catataacca ctggttttat atacagtata aaaattacgc
     7441 tgccttgttt ttcatgtcaa gtctgtaaat ttgcgttttt gtgaaaatga tcaaaaaaac
     7501 agccactcac accatgcgca atcccctcca gatgcaacaa aaaccagcac aaacggcgcc
     7561 gttctccggc ctcagtatgt tttactgaaa tcattatatg agataccaga aagccccccc
     7621 cgggacagga aaagaaacgg ggggtctggt tcgggttgtt cggtcactga acacggtcag
     7681 aaactgatga taagatagcc tgcggatata taactcaatg agaaaaaaga attaaaggta
     7741 aggagacgct catgagacgt tccggcagca aactgtgtct tatcgccatg ataacagcga
     7801 cagcaactct cactgcctgt gctccaaagg gcagcgtgga acagcatacc cggcattacg
     7861 tatatgcttc agatgacggt tttgatccca atttttccac ccagaaagct gacacaacac
     7921 gaatgatggt gccttttttc cggcagttct gggatatggg cgcaaaggat aaagcgaccg
     7981 gaaaatcacg gagtgatgtg cagcaacgca ttcagcagtt tcacagtcag gaatttttaa
     8041 actcactcca aggcacaaca caatttgcgg gtaccgatta ccgcagcaaa gacctcacac
     8101 cgaaaaaatc aaggctactg gctgacacca tttcagctgt ttatctcgat ggctatgaag
     8161 gcagacagta agtggattta ccataacgcg tcattacgcg caccgctcag acgggctcag
     8221 ggcgtttccg gcggctacgg gataaaacag gcaacaaccc ccccggaaaa ctgccggaaa
     8281 cgcgcccgat aaattttatc ctaatgcatg cctatgcacg caactgcatg gcatatgttt
     8341 tgacgtaaaa tggatgccgt aagccctttt ttaccgactt tctgcttcat cagcctgact
     8401 gacacgacca tattctttca gaccgccccc tgctaaactt ccttcatatt gccgcattaa
     8461 cccgggaggc tccgcaatga gcaacactac acactacgaa aacgccaact ttcttcggga
     8521 actggctgaa agcctgcccc gcatactgcc ggaaggtggc ccggacaaag ctgcgctgtt
     8581 gcagcgactg gctaacgaag aactggccca ggcagagtat gaagatcagg ttcgcgccaa
     8641 agtgaccgcc gcccgtgctg acacgcgtcc gggtatgacc acggaacaac tccgccagcg
     8701 cctgcatggc cgttatcagg aactgcgcga tgccgtatga cgtggaatgg aagcagggag
     8761 ccatcgagga tgtaacgacg ctgtttgact atatcgcgga aaattcatcc ctgtgggatg
     8821 cgcagaacgt taccgaccgg gttctcgctg cggcggacaa actggccgac ttcccgcgac
     8881 tctatgaagt ggactcacgc tatggcgagg acgttcgccg gatcagtctg atgggacagc
     8941 atgtcctcta tgatgttgat gaccagacca gaaaagtccg ggttctggcc gtggtcggcc
     9001 agcgccagaa tccccatatt gttctctaat aaccggtgac ggggacgcaa ttcattgcgt
     9061 ggccgtcgcc ggttggacaa gcacagcgcg tcagcgtttt ccccacggcc accaccggcg
     9121 cggtgttccg gccggggtct ctgctgtctc cggtttgtgt tccagcagtc tcatggactg
     9181 catttcctgc cgtagcccgg ccacctcctc cctgagtgct tttatctccg cgatcaacgc
     9241 gtcggaggcc attttttcag tctcacccga cagtctcaac tcgtcccgct cgtg
//
