LOCUS       NZ_CP032177             9294 bp    DNA     circular CON 26-NOV-2023
DEFINITION  Klebsiella pneumoniae strain AR_0135 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP032177
VERSION     NZ_CP032177.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04014976
            Assembly: GCF_003571545.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9294)
  AUTHORS   Conlan,S., Thomas,P.J., Mullikin,J., Frank,K.M. and Segre,J.A.
  TITLE     Whole genome sequencing of Klebsiella pneumoniae AR_0135
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9294)
  AUTHORS   Segre,J.A. and Mullikin,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2018) NIH Intramural Sequencing Center, 5625
            Fishers Lane, Rockville, MD 20852, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: canu v. 1.6
            Genome Coverage                   :: 132x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/26/2023 02:18:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,460
            CDSs (total)                      :: 5,340
            Genes (coding)                    :: 5,209
            CDSs (with protein)               :: 5,209
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 59 of 131
            Pseudo Genes (incomplete)         :: 68 of 131
            Pseudo Genes (internal stop)      :: 24 of 131
            Pseudo Genes (multiple problems)  :: 16 of 131
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032177.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="AR_0135"
                     /db_xref="taxon:573"
                     /plasmid="unnamed2"
     gene            complement(join(9141..9294,1..26))
                     /locus_tag="AM382_RS00660"
                     /old_locus_tag="AM382_00660"
     CDS             complement(join(9141..9294,1..26))
                     /locus_tag="AM382_RS00660"
                     /old_locus_tag="AM382_00660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            95..472
                     /locus_tag="AM382_RS00665"
                     /old_locus_tag="AM382_00665"
     CDS             95..472
                     /locus_tag="AM382_RS00665"
                     /old_locus_tag="AM382_00665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(534..833)
                     /locus_tag="AM382_RS00670"
                     /old_locus_tag="AM382_00670"
     CDS             complement(534..833)
                     /locus_tag="AM382_RS00670"
                     /old_locus_tag="AM382_00670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(823..1086)
                     /locus_tag="AM382_RS00675"
                     /old_locus_tag="AM382_00675"
     CDS             complement(823..1086)
                     /locus_tag="AM382_RS00675"
                     /old_locus_tag="AM382_00675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(1392..1811)
                     /locus_tag="AM382_RS00680"
                     /old_locus_tag="AM382_00680"
     CDS             complement(1392..1811)
                     /locus_tag="AM382_RS00680"
                     /old_locus_tag="AM382_00680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            2214..3899
                     /locus_tag="AM382_RS00690"
                     /old_locus_tag="AM382_00690"
     CDS             2214..3899
                     /locus_tag="AM382_RS00690"
                     /old_locus_tag="AM382_00690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            3909..4166
                     /locus_tag="AM382_RS00695"
                     /old_locus_tag="AM382_00695"
     CDS             3909..4166
                     /locus_tag="AM382_RS00695"
                     /old_locus_tag="AM382_00695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            4251..4400
                     /locus_tag="AM382_RS00700"
                     /old_locus_tag="AM382_00700"
     CDS             4251..4400
                     /locus_tag="AM382_RS00700"
                     /old_locus_tag="AM382_00700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            5881..7845
                     /locus_tag="AM382_RS00710"
                     /old_locus_tag="AM382_00710"
     CDS             5881..7845
                     /locus_tag="AM382_RS00710"
                     /old_locus_tag="AM382_00710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            7845..8576
                     /locus_tag="AM382_RS00715"
                     /old_locus_tag="AM382_00715"
     CDS             7845..8576
                     /locus_tag="AM382_RS00715"
                     /old_locus_tag="AM382_00715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            8583..9113
                     /locus_tag="AM382_RS00720"
                     /old_locus_tag="AM382_00720"
     CDS             8583..9113
                     /locus_tag="AM382_RS00720"
                     /old_locus_tag="AM382_00720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     BGC             1..8899
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(4504..5082)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7846..8573
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 agggctgttt tttcctgttt tgtcatgatt ctttccttcc gggcatggtg tgcgcctgtc
       61 aggtatactg tctcaaaaat agcggggtga gacaatggcg tgggtgacgg tgagacaggc
      121 gacggaactg acgggtaaag cccgaagttc cctgtatcgg gatatggcga aaggccgcgt
      181 atcataccgt acggaagctg atggcggccg ggtggtggat accagcgagc ttatccgggt
      241 gtacggtgag ttaagacagg atgagactca cgagcgggac gagttgagac tgtcgggtga
      301 gactgaaaaa atggcctccg acgcgttgat cgcggagata aaagcactca gggaggaggt
      361 ggccgggcta cggcaggaaa tgcagtccat gagactgctg gaacacaaac cggagacagc
      421 agagaccccg gccggaacac cgcgccggtg gtggccgtgg ggaaaacgct gacgcgctgt
      481 gcttgtccaa ccggcgacgg ccacgcaatg aattgcgtcc ccgtcaccgg ttattagaga
      541 acaatatggg gattctggcg ctggccgacc acggccagaa cccggacttt tctggtctgg
      601 tcatcaacat catagaggac atgctgtccc atcagactga tccggcgaac gtcctcgcca
      661 tagcgtgagt ccacttcata gagtcgcggg aagtcggcca gtttgtccgc cgcagcgaga
      721 acccggtcgg taacgttctg cgcatcccac agggatgaat tttccgcgat atagtcaaac
      781 agcgtcgtta catcctcgat ggctccctgc ttccattcca cgtcatacgg catcgcgcag
      841 ttcctgataa cggccatgca ggcgctggcg gagttgttcc gtggtcatac ccggacgcgt
      901 gtcagcacgg gcggcggtca ctttggcgcg aacctgatct tcatactctg cctgggccag
      961 ttcttcgtta gccagtcgct gcaacagcgc agctttgtcc gggccacctt ccggcagtat
     1021 gcggggcagg ctttcagcca gttcccgaag aaagttggcg ttttcgtagt gtgtagtgtt
     1081 gctcattgcg gagcctcccg ggttaatgcg gcaatatgaa ggaagtttag cagggggcgg
     1141 tctgaaagaa tatggtcgtg tcagtcaggc tgatgaagca gaaagtcggt aaaaaagggc
     1201 ttacggcatc cattttacgt caaaacatat gccatgcagt tgcgtgcata ggcatgcatt
     1261 aggataaaat ttatcgggcg cgtttccggc agttttccgg gggggttgtt gcctgtttta
     1321 tcccgtagcc gccggaaacg ccctgagccc gtctgagcgg tgcgcgtaat gacgcgttat
     1381 ggtaaatcca cttactgtct gccttcatag ccatcgagat aaacagctga aatggtgtca
     1441 gccagtagcc ttgatttttt cggtgtgagg tctttgctgc ggtaatcggt acccgcaaat
     1501 tgtgttgtgc cttggagtga gtttaaaaat tcctgactgt gaaactgctg aatgcgttgc
     1561 tgcacatcac tccgtgattt tccggtcgct ttatcctttg cgcccatatc ccagaactgc
     1621 cggaaaaaag gcaccatcat tcgtgttgtg tcagctttct gggtggaaaa attgggatca
     1681 aaaccgtcat ctgaagcata tacgtaatgc cgggtatgct gttccacgct gccctttgga
     1741 gcacaggcag tgagagttgc tgtcgctgtt atcatggcga taagacacag tttgctgccg
     1801 gaacgtctca tgagcgtctc cttaccttta attctttttt ctcattgagt tatatatccg
     1861 caggctatct tatcatcagt ttctgaccgt gttcagtgac cgaacaaccc gaaccagacc
     1921 ccccgtttct tttcctgtcc cggagggggc tttctggtat ctcatataat gatttcagta
     1981 aaacatactg aggccggaga acggcgccgt ttgtgctggt ttttgttgca tctggagggg
     2041 attgcgcatg gtgtgagtgg ctgttttttt gatcattttc acaaaaacgc aaatttacag
     2101 acttgacatg aaaaacaagg cagcgtaatt tttgtactgt atataaaacc agtggttata
     2161 tgtacagtat tttattttag tttattgttt taaaagtcaa agaggaaaag tatatgagtg
     2221 gcggagacgg acgaggtccg ggtaattcag gtctgggaca caatggtggt caggccagtg
     2281 ggaatgtgaa cggtacatca ggtaaaggtg gcccttcatc aggtggtggt acggatccaa
     2341 acagcgggcc gggctggggt acgacgcata cacctaacgg ggatattcat aactataacc
     2401 cgggggagtt tggtaacggc gggagtaaac ccggtggtaa tggcggtaac agcggcaatc
     2461 atagcgggag ctctggtggc ggacagtctt cggccaccgc gatggccttc ggtctgcctg
     2521 ccctggccac tccgggggct gaaggactgg ctttatccgt ttccggcgat gcgttgtcgg
     2581 ccgctgttgc tgatgtgctg gctgccctga aaggtccgtt taagtttggt ctgtggggga
     2641 ttgcgattta cggagtgctg ccttctgaga tagcaaaaga tgatccgaaa atgatgtcaa
     2701 aaatcgtgac gtcattgccg gcagacacgg taacggagac gccggtcagc tccctgccgc
     2761 tggaccaggc gacggtcagc gtcactaaac gtgtggcgga tattgtgaag gacgagcggc
     2821 agcatattgc ggttgtcacc ggccggccaa tgagtgttcc tgtggtggat gcgaaaccga
     2881 caaaacgtcc gggggtattc agtgtgtcga ttccgggtct cccgtctctg caggtgagcg
     2941 tacctaaagg tgttccggcc gcgaaagccc cgccaaaagg cattattgct gaaaaaggtg
     3001 attcacgtcc ggctggtttt acggccggtg gtaactcccg tgaggccgtt attcgtttcc
     3061 cgaaagagag cggacagaaa ccggtctatg tgtcggtgac ggatgttctt actccggcac
     3121 aggtaaaaca gcgtctggag gaagaaaagc gtcgccagca ggcatgggac gctgctcacc
     3181 cggaagaggg gctgaaaaga gagtatgata aagcgaaagc tgagctggat gctgaagata
     3241 aaaatattgc gaccttaaac agtcgcattg catcgacaga gaaggcgatc cccggtgcaa
     3301 gggctgctgt tcaggaagcc gataaaaagg taaaagaggc agaggcaaat aaagatgatt
     3361 ttgtgactta taacccgcct catgaatatg gctccgggtg gcaggatcag gttcgctatc
     3421 ttgataagga tattcagaat cagaatgaga aattaaaagc tgcccagaca tctttaaacg
     3481 aaatgaatga atccttatcc agggataagg ctgcgctttc cggggcgatg gagagccgga
     3541 aacaaaagga gaaaaaagcg aaggatgcag aaaataaatt aaatgaggaa aagaaaaaac
     3601 ctcgtaaggg aactaaagat tacggccatg attattttcc tgatcccaag actgaagata
     3661 ttaaggggtt gggagagttg aaagagggta aacctaaaac ccctaaacaa ggtggtggtg
     3721 gtaagcgggc ccgatggtat ggtgataaaa agcgtaaaat ttatgaatgg gattcccagc
     3781 acggtgagct tgaagggtac cgcgccagtg atggcgaaca cctcggggca ttcgatccaa
     3841 aaacgggtaa gcaggttaaa gggccggatc caaaacgaaa cattaaaaaa tatctttaag
     3901 aggtaaatat ggggcttaaa ttacatattc attggtttga taagaaaacc gaagagttta
     3961 aaggtggtga atactcaaaa gacttcggtg atgatggttc tgtcattgaa agtctgggga
     4021 tgcctttaaa ggataatatt aataatggtt ggtttgatgt tgaaaaatca tgggtttcga
     4081 tattacagcc acactttaaa aatgtaatcg atattagtaa atttgattac tttgtatcct
     4141 ttgtttaccg ggatggtaac tggtaagcaa aagttatcaa ggatgatttg aaatacagac
     4201 ttccggtgtt cagggatgaa taccggggtt tttaaataca gggaaggtat atgaaaaagg
     4261 taaaggttgt ttttcttttt atattgattt tttcaggctt tcttctggtc gcatgtcagg
     4321 caaactatat ccgggatgtt cagggtggaa cggtggcacc atcgtcctcc tctgaactga
     4381 cggggatcgc ggttcagtag aaaagatcaa aggatcttct tgagatcctt tttttctgcg
     4441 cgtaatcttt tgccctgtaa acgaaaaaac cacctgggga ggtggtttga tcgaaggtta
     4501 agtcagttgg ggaactgctt aaccgtggta actggctttc gcagagcaca gcaaccaaat
     4561 ctgtccttcc agtgtagccg gactttggcg cacacttcaa gagcaaccgc gtgtttagct
     4621 aaacaaatcc tctgcgaact cccagttacc aatggctgct gccagtggcg ttttgcgtgc
     4681 ttttccgggt tggactcaag tgaacagtta ccggataagg cgcagcagtc gggctgaacg
     4741 gggggttctt gcttacagcc cagcttggag cgaacgacct acaccgagcc gagataccag
     4801 agtgtgagct atgagaaagc gccacacttc ccgcaaggga gaaaggcgga acaggtatcc
     4861 gggaaacggc agggttggaa caggagagcg caagagggag cgattcatcg gaaacggtga
     4921 tgatctttaa gtcctgtcgg gtttcgccac tcctgactga ttcatggttg agccaccggc
     4981 tcccacagat gcaccgaaaa agcgtctgtt tatgtgaact cagtcaggag ggcggagcct
     5041 atggaaaaac gccacctgcg tggccttgcc gttttgcctc acatgttagt cccctgctta
     5101 ttcacggaat ctgtgggtaa ctttgcatgt gtccgcagcg cccgccgcag tctcacggcc
     5161 ggagcgtagc gaccgagtga gcgaggaggc gcaatttccc cggcacctac aagacggaca
     5221 ccggacgcgc tgatgtggca tattgtcccc tgattaagtc tttatattcc ctgataataa
     5281 attaccagga taggtgaatc atatcggttt ttcgctgaac attttacgtt aacctatctc
     5341 tgttgctttt ttctccttac ggagaaatac aggtcatccc cgcgagggcg tggctgacct
     5401 cagggggata tcccctgctt acgctggctg gacgccaccg acgcacggtc tctccccctc
     5461 tttctggctc cgtccggctg gacgccggcc acgccagaaa ttcacccggc ccccgtcagg
     5521 ctcacgcctg accacccaca aaaatccacg gtgctggacg cacctggcga agcagcaaag
     5581 ctgctcctga ttttgcgggt ggtcagccgc tcgctatggc gaactctgac gggggccgga
     5641 acaccggaaa agaccgcact ggggtgccgc cttttcctct cacacgctgg ggcgtgctcg
     5701 ttgttcctcc ggggctgcgc cttttccgca tggggcggaa agaggctggc ctccgtggtg
     5761 aaagctgaac gcaatcacca cggacgtgac cgccgccgcc atgccttggg gcatgtccgc
     5821 ggcttgtgca gcgggggctg cacatcacgc cggcaaacca tcgtctgaag gagagagaac
     5881 atgtttaata cggattcgct tgcctggaag tggcacattc cggagctggc ccggcagatt
     5941 tatccgtggg tcagctggct gtaccaggag tattacggtc tggccggggc tttcctagtt
     6001 atcggcctgt ttttcggtct ggctgaactt tgggccggac ggatgcgttt tgtggggctg
     6061 agtcataagg agcgacggga gtatgccgat cgctataagc gcgataataa acggccagcg
     6121 ccattttcgg tgctggcctc gctggattcg cccgggcgga tggtcagggc acgtcgacat
     6181 gtctggaact acgcgtactg gctgaccggc gcggccggtc tggcccttct gggggggctg
     6241 gttgtcgccg tgtttatcga gagctgggga gaaaccgtcc tgcgtccgga cctctacgca
     6301 aacgcagatt attacctgct gcagccggct aacctgttcg ggattgcctg gtgcgcgggc
     6361 gggctggctg tcgggattgt gttggcgcgg ctgctggcgt tcctgctgct tgacggtcat
     6421 tttgcggctg ctgacgaggc ggtgaacgcg aaactgaatc aggagagccg gcgcagcagc
     6481 cagcggacag gagagatgac cgacgtgcgc cacctgcatt tcggggagcc ggtaccggtt
     6541 aatgcgctgg ccgatttttc ctcggagcag gcccggcagg agcaggcggt gtttctgggt
     6601 aaggatgagc agggcaagcc ggtgctggtt ccgcgtgata cctggcgcaa gaccaacatt
     6661 cagatcctcg gcctgcccgg gagcggcaag agcgtgatgg ccaccaacgc gctcattcgc
     6721 tgcgtacgcg atttcgggga cgcggtggtg tacttcgacc ccaaagggga cgcatgggcg
     6781 ccgcacgtct tccgggcgca ctgtccggac ttcaccctgc tggatctgcg gccggggaaa
     6841 ccggcgcagc tgaatctgtt ccgcgatctc gaccagtacg cgctgaaaaa cctgctgatt
     6901 gccgggctta acctgggcga gaccggcgac gtggcggacc actaccgcat cagcgagcag
     6961 aaagcggcga agctgattgc ggagcagttt ccgcaggggg caaacattca gcaggtgctg
     7021 gcggcggcgt acgcgctgcc ggaggccctg aaaaaggacg tgaaggggtt gatcactagg
     7081 ctggaaaacg tcgctgacct gagcgtcctg cagacggaca gtggcatcga tgtggcgggg
     7141 attatcaacg gcggcggctg cctgtacgtt atcggctcga tggacgacga ggcggtgatc
     7201 cgtgtgcaaa aaatgctgtt tgcccgctgc gcgcaaatca tcattgcgcg ggacgagttc
     7261 cgggagtggc cacacgtcag cgtgatgctc gatgaaatta aatatctgct gtcgaagtat
     7321 gtactgaacg cactggggac gctgcgcagc cgggactgca atctgttgct cgcgcaccag
     7381 tcgctgggcg atttcgggca gtgcgggcag gatctgcccg ctgaatttgt gaaaaccacg
     7441 gtactggata acacgccgat ccgctggttt taccgggcgg ccagcctgga gtccgcgcag
     7501 tgggcggcgg ggcagaccgg ggaaatcagg gtggacgtgg agcgccgccg tgccagccgg
     7561 gaggcgggga acgtggagca tatcagcggg gacagcttca tccagaagga ggcgcggccg
     7621 ctgtttgacg tgaacaccct gcaacacctg ccggacgggt tcgcggtcat gaccgggctg
     7681 ggtgtggccc ggatggcgtt cagcagtccg ctgcgggttg agcgccggga aatcccgttg
     7741 cagcgtttcc cggtgctggc gaaaaccgat cccctggcgg agttccggcc cccggccgac
     7801 ggcggcgggc cgaaagcgga tgatgatttt gcggggattt actgatggcg ctggagctgt
     7861 acaacgtcag ccacgcgaaa cgacaggcgc ggaacgcgga gaaaacccgg ctgaccctgc
     7921 gctggttgcg ggaagagctg tgttccacgg cggagctggt tgcgcggcgg ctggggattg
     7981 cggcggtgca gccggtctac cgcttcctcg acagcctggt ggcgaaaggg ctgctggtcc
     8041 ggaccaaata tccggtggac ggccgtcagg tcagcgtgtg ggggctgacg ccgcatggcg
     8101 tggcgttctc gttcgacgag gacgaaccgc tggcggatgt tattccgttt cagccgtcaa
     8161 gggtgtcggc agcacatctg ccgcaccggc tggccgtgca atccctgcgc cttgatatgg
     8221 aagccagagg ggccaccggc tggcgcattc tgcaccgtct gagtcttaaa ggcatgaaag
     8281 tgccggacgc cctggcggag ctggacggta aaacggtggc gtttgaggtg gagcgcaccg
     8341 tcaagagccg tcgccggtat caggaagtgg tgtccgggta tctgttcaac cgcaaagcta
     8401 acggcatcga tgaaatctgg tacatctgcc cggaccgggc gacgcaggtc agggtgcagc
     8461 gggcaatcct gtcggtggat gaaatcgtga acccacagac cggcgaggcc cgcaaaacgg
     8521 cagagctgga tcgtgaacgg ttgtttgcgt gctttaaatt tatgacaacg gagtgaggga
     8581 ttatggcgct gtacatggta tttattgaag acgcggagga ccggaacggc gagcgctgca
     8641 tcatgccgac cagcgagcat ctggaagata tggtggtgct cgcctggcag accggggcgt
     8701 atgttttctg ttttgtcgac cgggcccagc atctggcgat gatgaaatcc atcgggatgt
     8761 atgacgagcg gctcaacagc gacgaaaaag ccacgtactt tttcactggt aaaaatccgc
     8821 aatgggaacg gaacaaaccc acaggaatga agctgtgtga ttacctctat cgcaaggtgg
     8881 agcggttcgc catcgagaac ggtgtgcagg tggttgatgc cgggaagtgc tcaccggagc
     8941 agattaacgc gatgattgac gtggtgagtg agcggcacgg ggaaagcgcg gtgaacgaga
     9001 agctgaaagc ggagctgatg cgggaatata acagccgcta ttttaacgtg ccggtacctg
     9061 aactgccgga ggacaaacct gcccgccggt ggtggccgtt cggcaaaaaa taaatgccag
     9121 caccggccat gccggtgctg ttattcctcc ccgagcttat cccgcatcac ctgccagagt
     9181 gtttccgcat cctcgtgtag ccgctcgcac atgtcggccg gggtatccat atccagctca
     9241 ttcagtttat cgagcaatag cagcgactgc tccttaataa atttagccat attg
//
