LOCUS       NZ_CP031999             9485 bp    DNA     circular CON 05-JAN-2024
DEFINITION  Acinetobacter haemolyticus strain INNSZ174 plasmid pAhaemINNSZ174c,
            complete sequence.
ACCESSION   NZ_CP031999
VERSION     NZ_CP031999.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN09927969
            Assembly: GCF_009892365.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter haemolyticus
  ORGANISM  Acinetobacter haemolyticus
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter.
REFERENCE   1  (bases 1 to 9485)
  AUTHORS   Castro-Jaimes,S. and Cevallos,M.A.
  TITLE     Analysis of the genomic diversity of Mexican Acinetobacter
            haemolyticus clinical isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9485)
  AUTHORS   Castro-Jaimes,S. and Cevallos,M.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-AUG-2018) Evolutionary Genomics Program, Center for
            Genomic Sciences, National Autonomous University of Mexico (UNAM),
            Av. Universidad s/n Col. Chamilpa, Cuernavaca, Morelos 62210, Mexico
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2018
            Assembly Method                   :: Unicycler v. 0.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 259x
            Sequencing Technology             :: Illumina MiSeq and PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 04:23:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,431
            CDSs (total)                      :: 3,339
            Genes (coding)                    :: 3,208
            CDSs (with protein)               :: 3,208
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 29 of 131
            Pseudo Genes (incomplete)         :: 97 of 131
            Pseudo Genes (internal stop)      :: 21 of 131
            Pseudo Genes (multiple problems)  :: 14 of 131
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031999.1.
            Bacteria available from Submitting center.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9485
                     /organism="Acinetobacter haemolyticus"
                     /mol_type="genomic DNA"
                     /strain="INNSZ174"
                     /host="Homo sapiens"
                     /db_xref="taxon:29430"
                     /plasmid="pAhaemINNSZ174c"
                     /geo_loc_name="Mexico: Mexico City"
                     /collection_date="1998-05-21"
                     /collected_by="Instituto Nacional de Ciencias Medicas y
                     Nutricion Salvador Zubiran"
     gene            join(9305..9485,1..1049)
                     /locus_tag="AhaeINNSZ174_RS16965"
                     /old_locus_tag="AhaeINNSZ174_17085"
     CDS             join(9305..9485,1..1049)
                     /locus_tag="AhaeINNSZ174_RS16965"
                     /old_locus_tag="AhaeINNSZ174_17085"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_068569691.1"
                     /translation="MSDQVSATLKTLLNTMQLLSESLENEKQQHIELLKKLNSHVSNSQ
                     TEIKNDFFDFLNKIELQEFVSIVQDSKLNIENNQKSILQLNAEIMQIRQTAKQSLAELE
                     QQNLDLSKKISGSSDKITSDIIKNVANDVKESVTQNFSLQFKEQNQTLILEAKKANSTV
                     ITNIIEIYNHLNKQVLSVTKDHRESLSQFKTDVSAFTESINIAINSVKDSFAEVEELNK
                     DQMKQLYESSLNFRKHVLDKINAETENINSIFDDEINNISKNVQTHCNNVLNKMSETED
                     LVDQKANLISLKLNDSLTTTEKIIVKQTNYYENLYKRLNFNYFAINTSSILAFFLVVLS
                     ALCITAFIQNKSLEKDNLALQSQNKKLNEDGVLLASIKNDSIKLTKQSISDVKKKFPTL
                     IVTLNCKALD"
                     /name="hypothetical protein"
     gene            complement(1155..1565)
                     /locus_tag="AhaeINNSZ174_RS16970"
                     /old_locus_tag="AhaeINNSZ174_17090"
     CDS             complement(1155..1565)
                     /locus_tag="AhaeINNSZ174_RS16970"
                     /old_locus_tag="AhaeINNSZ174_17090"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family toxin"
                     /protein_id="WP_063454736.1"
                     /translation="MEYLLDTNIVGYILKGVASNKLKNKLMMINPDDVFISQITHAEII
                     YGLQKGGNIIKHINRVNSFLETLSILDWDEQCAHAYGKVRNELRLQGVTVQSMDLMIGA
                     HAIGHNMTLISNDHIFDHFKQFGLVLENWQTA"
                     /name="type II toxin-antitoxin system VapC family toxin"
     gene            complement(1565..1804)
                     /gene="vapB"
                     /locus_tag="AhaeINNSZ174_RS16975"
                     /old_locus_tag="AhaeINNSZ174_17095"
     CDS             complement(1565..1804)
                     /gene="vapB"
                     /locus_tag="AhaeINNSZ174_RS16975"
                     /old_locus_tag="AhaeINNSZ174_17095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012969851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_063454737.1"
                     /translation="MNHIAKIFMNGQSQAVRLPKQFRFESKVVYVRRNTKGEVILSEKP
                     RTWTEFFNENSDVLGFETLMADREQDMPFERDLF"
                     /name="vapB"
     gene            complement(2316..3149)
                     /gene="fghA"
                     /locus_tag="AhaeINNSZ174_RS16980"
                     /old_locus_tag="AhaeINNSZ174_17100"
     CDS             complement(2316..3149)
                     /gene="fghA"
                     /locus_tag="AhaeINNSZ174_RS16980"
                     /old_locus_tag="AhaeINNSZ174_17100"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439570.1"
                     /GO_function="GO:0018738 - S-formylglutathione hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0046292 - formaldehyde metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="WP_160132610.1"
                     /translation="MERIEHHASFEGWQDVFQHESTVLGCMMRFGIYLPPQAEHEKLPV
                     LYWLSGLTCTEQNFITKAAVQRYAAEHGIIVVAPDTSPRGESVADDAAYDLGQGAGFYV
                     DATELPWSDHYQMYSYVVDELPALIEANFPTSSRRSISGHSMGGHGALVIALRNPGRYA
                     SVSAFSPIVAPTQVPWGQKALAAYLGEKNLEAWKQYDTVELIRVAQERLPLLVDQGLSD
                     EFLEHQLRPQLLRTACEQVDHPLTLNLRPGHDHSYYFISTYLSEHMAHHAAALNR"
                     /name="fghA"
     gene            complement(3623..4021)
                     /locus_tag="AhaeINNSZ174_RS16985"
                     /old_locus_tag="AhaeINNSZ174_17110"
     CDS             complement(3623..4021)
                     /locus_tag="AhaeINNSZ174_RS16985"
                     /old_locus_tag="AhaeINNSZ174_17110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009639360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="WP_000235176.1"
                     /translation="MATPVISGNDIFSHVFLGAVDLKKSVVFYDAALGALGIKNLGPFG
                     NDWVLYGRDKPAFMITRPSNGAEPTSNGVTVGFAAATPAEVNAFHAAGLAAGGTDEGQP
                     GPRGHLPGAYAAYLRDPAGNKVCAYTFV"
                     /name="VOC family protein"
     gene            complement(4074..5183)
                     /locus_tag="AhaeINNSZ174_RS16990"
                     /old_locus_tag="AhaeINNSZ174_17115"
     CDS             complement(4074..5183)
                     /locus_tag="AhaeINNSZ174_RS16990"
                     /old_locus_tag="AhaeINNSZ174_17115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_004995413.1"
                     /GO_function="GO:0004024 - alcohol dehydrogenase activity,
                     zinc-dependent [Evidence IEA]; GO:0051903 -
                     S-(hydroxymethyl)glutathione dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006113 - fermentation [Evidence IEA];
                     GO:0009404 - toxin metabolic process [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase/class
                     III alcohol dehydrogenase"
                     /protein_id="WP_000842148.1"
                     /translation="MKSRAAVAFGPGQPLQIVEVDVAPPKKGEVLIKISHTGVCHTDAF
                     TLSGDDPEGVFPAILGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECVFCKSGKSN
                     LCISVRETQGRGVMPDGTTRFSYNGQPIYHYMGCSTFSEYTVVAEVSLAKINPEANHEH
                     VCLLGCGVTTGIGAVHNTAKVQEGDSVAVFGLGGIGLAVVQAARQAKAGRIIVVDMNPD
                     KFALAKEFGATDFLNPKDYDKPIQQVIVEMTGWGVDHSFECIGNVNVMRAALESAHRGW
                     GQSVIIGVAGAGQEISTRPFQLVTGRKWLGSAFGGVKGRTQLPGMVEDAMKGKIQLEPF
                     VTHTMGLDQINEAFDLMHEGKSIRTVIHY"
                     /name="S-(hydroxymethyl)glutathione dehydrogenase/class III
                     alcohol dehydrogenase"
     gene            complement(5205..5480)
                     /locus_tag="AhaeINNSZ174_RS16995"
                     /old_locus_tag="AhaeINNSZ174_17120"
     CDS             complement(5205..5480)
                     /locus_tag="AhaeINNSZ174_RS16995"
                     /old_locus_tag="AhaeINNSZ174_17120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal/formaldehyde-sensitive transcriptional
                     repressor"
                     /protein_id="WP_001133626.1"
                     /translation="MPNQVEDKKKILTRVRRIKGQAEAIEKALEDNVECGAILQQICSV
                     RGAINGLMNEMLEVHLKDTLVSGETTEQQRKEELAEIAKILKSYLK"
                     /name="metal/formaldehyde-sensitive transcriptional
                     repressor"
     gene            6324..7253
                     /gene="repM"
                     /locus_tag="AhaeINNSZ174_RS17000"
                     /old_locus_tag="AhaeINNSZ174_17125"
     CDS             6324..7253
                     /gene="repM"
                     /locus_tag="AhaeINNSZ174_RS17000"
                     /old_locus_tag="AhaeINNSZ174_17125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004779686.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_068599699.1"
                     /translation="MKNGLVVKDNALINASYNLELTEQRLIMLAIINARELGQGITADS
                     KLEIHASDYAKLFNVSTDASYKALKEAVNNLFNRQFSYTAEYKKTGKVGVVRSRWVSRI
                     FYVDDLALLEITFAPDVVPLITRLEEHFTKYEAKQVAHLTSKYATRLYELLIAWREVGK
                     TPIFELQQLRKNLGVEDDEYQRMHHFKNRVLDTAITQINEHTDIKTTYEQHKQGRTITG
                     FSFRFKQKSQPKIEIKRDTNTPDFFVKMTDAQRHLFANKMSEMPEMSKYSRGTESFQQF
                     AIRIADMLLEPEKFRELYQCLEKAGFQA"
                     /name="repM"
     gene            complement(7265..7576)
                     /locus_tag="AhaeINNSZ174_RS17005"
                     /old_locus_tag="AhaeINNSZ174_17130"
     CDS             complement(7265..7576)
                     /locus_tag="AhaeINNSZ174_RS17005"
                     /old_locus_tag="AhaeINNSZ174_17130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004647573.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_063454740.1"
                     /translation="MNKADIIAKLAPKLYITQDEARVILNSVLEVFTEALVEEKSLKLV
                     DFGTFSVQKRAERIGRNPKTGDLINIPEREVVTFKQGKALGEKFLVKAKPKGKIKNAK"
                     /name="HU family DNA-binding protein"
     gene            complement(7579..7857)
                     /locus_tag="AhaeINNSZ174_RS17010"
                     /old_locus_tag="AhaeINNSZ174_17135"
     CDS             complement(7579..7857)
                     /locus_tag="AhaeINNSZ174_RS17010"
                     /old_locus_tag="AhaeINNSZ174_17135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004647572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063454741.1"
                     /translation="MSIENLEQKIEKQEERLKQLKAQKQAIEAREKKKISEQQRKDETR
                     KKILLGSYLLKEMEDETEKTKILANLNTYLTQDRDRKLFDLPSIEEN"
                     /name="hypothetical protein"
     gene            8091..9287
                     /gene="mobQ"
                     /locus_tag="AhaeINNSZ174_RS17015"
                     /old_locus_tag="AhaeINNSZ174_17140"
     CDS             8091..9287
                     /gene="mobQ"
                     /locus_tag="AhaeINNSZ174_RS17015"
                     /old_locus_tag="AhaeINNSZ174_17140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005804952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="WP_068599703.1"
                     /translation="MAIYHFSVKNISRSDGRSAVACAAYRSAEKLTCDYYGKEQDYTRK
                     IGVEHTQIYAPENTNINLLNRQKLWNSVEKVERRKDATLAREFEIAFPNELNAEQRKSM
                     LDDLCKKLVEKYGAVVDAAIHAPHKNSGSDERNYHAHIMFTTRSIDLETGEFSAKKFRD
                     FNKEVGSKTVKNWRSYFADLTNLHLEKAGFDIRVDHRSNRARGLDLEATLHEGSKVTQL
                     RRMNIETEISLKNDAIKQRNLLSSMPDLEHEIIATSKLLQQLKFEQSKLQTQSRESAFD
                     DILNTASSKLTEINETFDKITENVNENGSQKNIFDTLDSSISSLSKNELFSSLSDSINN
                     QAEHERQAEHERQAERERQAEHERQAERERQAERERQAERERQVEREQTRNNNYTPDF"
                     /name="mobQ"
     Typing          6325..7251
                     /name="rep_cluster_1265"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.828"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          8092..9284
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttcaagagtt cgtgtcaatc gttcaagatt caaagcttaa tatcgaaaat aatcagaaaa
       61 gcattcttca attaaatgct gaaatcatgc agatcagaca gactgcaaag caatcactcg
      121 cagagctgga gcaacaaaac ttagatcttt ctaaaaaaat tagtggcagc agtgacaaaa
      181 taactagcga tattataaaa aatgttgcta acgacgtaaa agaaagcgtg acacaaaact
      241 tttcactaca gtttaaagag caaaaccaaa cactgatttt agaagctaaa aaagcgaaca
      301 gcactgtcat tacgaatatt atagaaatct ataatcactt aaacaaacaa gtattgagtg
      361 tcacaaaaga tcatcgagaa agtctctctc agtttaaaac tgatgtcagc gcatttacag
      421 aaagcattaa tattgcaatc aacagcgtaa aagattcatt tgctgaagtt gaagaattaa
      481 ataaagatca gatgaaacaa ctttatgaat catctcttaa ttttagaaag catgttcttg
      541 ataaaataaa cgcagaaacg gaaaatatta atagtatttt tgatgatgaa attaataata
      601 tttcaaaaaa tgtgcagact cattgtaata atgttttaaa taaaatgagt gaaacagaag
      661 atttagttga tcagaaagca aatttgatca gtttaaaact aaacgatagt ttaacgacaa
      721 ctgaaaagat catagtcaaa caaacaaact attatgaaaa cctatataag cgattgaatt
      781 ttaactattt tgcaatcaac acaagttcaa ttttagcttt ttttttggtt gttctcagcg
      841 cactatgcat taccgcattt attcaaaata aaagtttaga aaaagataat ttagcgcttc
      901 aaagtcaaaa caaaaagctt aatgaagatg gtgtattact cgcgtcgata aaaaatgact
      961 cgatcaaact tacaaaacaa tcaatttcgg atgtaaagaa gaagtttcca acgctgatag
     1021 tcactctcaa ctgcaaagca cttgattagt tcgcccagaa cgccacaatt tacgatctaa
     1081 gcgatttaaa tctgatttac attaatccct atcagtatca tgtaaaaatc gcttaaatcg
     1141 ctttatatgc ctaatcaggc ggtttgccaa ttttctagca ctaatccaaa ttgtttgaaa
     1201 tgatcaaaaa tatgatcatt actaatcaaa gtcatattgt gaccaatggc atgagcacca
     1261 atcattaagt ccattgattg aacagtaaca ccttgtaggc gtaattcatt acgaactttg
     1321 ccataagcat gggcacattg ttcatcccaa tctaaaatac tcagtgtttc taaaaaagaa
     1381 ttaactcgat taatatgttt gatgatattc ccacccttct gcaaaccata aataatttca
     1441 gcatgggtaa tctgtgaaat gaaaacatca tcgggattaa tcatcattaa tttatttttt
     1501 agcttattac tggcaacacc ttttaaaata tagcccacaa tattggtatc aagtagatat
     1561 tccattaaaa aagatctctt tcaaatggca tatcttgctc acgatcagcc attagggttt
     1621 caaaacccaa cacatcacta ttttcattaa aaaactctgt ccatgtacga ggtttttcag
     1681 aaagaataac ctctcctttt gtatttcttc tgacataaac aactttgctt tcaaagcgaa
     1741 attgttttgg tagtcgtacc gcttggcttt gcccattcat aaagattttt gcaatatgat
     1801 tcatgataca ccctcctttt ttaatatact aaatagtata tattaaatag agatcggtgc
     1861 aatcataatg tcaaatcttg ataaatatga ttggcaagaa ctgtcaaaac cgatcataaa
     1921 aaagtcgact tgtttccaag ccggcttttc gacatcgtcg agcacattct ttatatcata
     1981 agtttttgat ttttataagt ttcaatgtat gcacttcgta taacgcccat tatgttaaat
     2041 ggatagttaa ctacatggta tttctgttcg attaactagc tctttcagct tttccaagaa
     2101 atcacggctt agtattagct cctctacttt tttatctgat atgggctttg ttgcataaag
     2161 attttgtaag cttctgattt aaataggttt gtatgaattt caacctaaaa attaaatgaa
     2221 caaaatcagt tggttatgta tttatgcaac aaagcccctt aaaaccaaat agaaatgtcc
     2281 tatacagaca tttccaagtc agggtctccc aatgttcagc gattcaatgc agccgcatgg
     2341 tgggccatgt gttcgctcaa gtaggtcgaa ataaagtagt agctatggtc atgaccaggc
     2401 cgcagattga gcgttagcgg gtggtctacc tgttcacacg cggtacgcaa cagttgcggt
     2461 cgaagctggt gctcgagaaa ctcatcgctc agcccttgat cgacaagcag cggtaagcgt
     2521 tcttgcgcca cgcgaatcag ctcgaccgtg tcatattgct tccaggcttc cagattcttt
     2581 tcgcccaagt aagccgccag agccttctgc ccccatggaa cttgcgtagg cgccacgatc
     2641 ggcgagaacg ccgagacact tgcatagcga ccggggttgc gaagcgcaat aaccagagcg
     2701 ccatgaccgc ccatggagtg cccactgatg ctgcgtcttg acgacgtagg gaagttcgct
     2761 tcgatcagcg ctggtaattc gtcgaccaca taggaataca tctgatagtg atcgctccaa
     2821 ggtagctctg tggcgtctac atagaaaccc gcaccttgac ctagatcata ggcagcatcg
     2881 tctgcaacgc tttctccgcg cgggctggta tctggggcta cgacaatgat tccgtgctcc
     2941 gcggcatacc gctgcaccgc agccttggtg atgaagttct gttcggtaca ggtcagacct
     3001 gagagccagt acagaactgg gagcttttca tgctcagcct gaggcggaag atagattcca
     3061 aacctcatca tgcagccaag cactgttgac tcatgctgaa aaacgtcctg ccaaccctcg
     3121 aagctggcgt gatgttcaat gcgttccacg gattttctcc ttatttcaac gaggtggtgc
     3181 tcaggcgcca atcaagacga attttcgttc catccaggat tagttaaaaa tgcttcaccg
     3241 caccactcag caggttttca gcgttgtcgc tggcatgaag atcgctgcta caaacccaga
     3301 cgccaccaca ccacgaaggt cggatgtcga cttcaatgta caaacaataa agtgtgtaat
     3361 tcagggagcc actaccgcga tgctcatttt ggattctgtg tttcttgcat cacgcaccga
     3421 actttcagtc cgatcgtgct cattgaccgt ctttggctat gaaggcgagg taacagcctt
     3481 tctgagctct aatcagcaga tagaggctca gagtaccgta aaccgtgtgg catgagcggg
     3541 catgccacac ggttgcagtg gaagatgaga ttgtttttgg ctggaaccag tccttacaca
     3601 atgacctcac ttctcctagg ttttagacaa aggtgtaggc gcagacctta ttaccagccg
     3661 gatcacgcag gtaggccgcg taagcacccg gcaggtggcc acgtgggcca ggctgacctt
     3721 catcggtgcc accagcggcg aggccggctg cgtggaatgc atttacctct gcaggggtgg
     3781 cagctgcgaa gcctaccgtc acaccattac tggtgggttc tgcgccattg cttgggcggg
     3841 tgatcatgaa agcaggtttg tcgcgaccgt acagaaccca atcgttaccg aatggcccta
     3901 ggtttttaat gccgagggca cctagagcgg catcgtagaa tacaaccgac ttcttaaggt
     3961 cgactgcgcc gaggaagaca tgggagaaaa tatcgttacc ggaaattact ggagtagcca
     4021 ttaaagtgtt tccttgatgg ttggttttga aaaattaggt attgatccgt ggatcaatag
     4081 tgaatgacag tgcgaattga cttaccttca tgcattagat caaaggcttc attgatctga
     4141 tccaagccca tcgtatgtgt cacaaatggt tctaattgaa ttttaccttt catggcatct
     4201 tcaaccattc ctggaagttg cgtacgacct tttacgccac caaaggcaga acctagccat
     4261 ttacgaccag taaccagttg gaatggacgg gtagagattt cctgacctgc gccagctaca
     4321 ccaataatta cggattgtcc ccagccacgg tgtgcacttt caagggctgc acgcattaca
     4381 ttcacgttgc caatacattc aaatgaatga tctacacccc agccagtcat ttcgacaatg
     4441 acttgctgga ttggtttatc gtagtcttta gggttcaaga agtccgttgc accaaactct
     4501 tttgccagcg caaatttatc tggattcatg tcaaccacaa taatacgccc tgctttagct
     4561 tgacgtgcgg cttgtacgac tgccaaacca ataccaccta aaccaaagac cgcaacacta
     4621 tcaccttctt gtactttagc cgtgttatgt actgcaccga taccggttgt taccccacaa
     4681 cccagtaagc agacatgttc gtgattggct tcaggattga ttttagccaa tgatacttct
     4741 gccactacag tgtattcact gaacgttgag cagcccatat agtggtaaat cggttgacca
     4801 ttgtaggaaa agcgagtggt accatctggc attacgcctc taccttgagt ttcgcgaacg
     4861 gaaatacaca agttcgattt tccagattta cagaatacgc actcgccaca ttcagcagtg
     4921 taaagtggaa taacatgatc acctggtttg acgctagtca cgccttcacc aacctcaact
     4981 acaacaccag caccttcatg cccgagaata gccggaaaaa cgccttcagg atcatcgcca
     5041 gataaagtaa atgcgtctgt atgacacaca ccagtatggg agatcttgat taatacttca
     5101 cctttcttcg gtggtgcaac atcaacctca acaatttgaa gaggttgacc aggaccaaac
     5161 gcaacagcag cacgtgactt catggaataa ttccttatac agatctattt taaatatgat
     5221 tttagaatct tggcgatttc agccaattct tcttttcgtt gttgttctgt ggtttcacct
     5281 gatactaaag tgtcctttaa atgaacctcc aacatttcat tcattaaacc attaatagca
     5341 ccacgcacag agcatatttg ttgcagaatt gcaccacatt ccacattgtc ttctaaagct
     5401 ttttcaatcg cttcagcctg acccttgatt cgtctgacac gcgtcagaat ctttttttta
     5461 tcttcgactt gatttggcat aaagctaatt ccttaaattt tattatagta tagtacccta
     5521 tagtatatag aatgacaaga agcctttata aaattaataa ttgataaaag cttataatta
     5581 aaaaattcta tatctatttt taagttttta taaaattaac ataatacacc ttatacgaaa
     5641 tgtgttataa ttttccttag aaatcaatgc tgtagtttct agtttatagc ccatcttccc
     5701 caaggtgggc tttttttatg attttttacg ttccacgcct attctttgat caatgtttca
     5761 caactttgat tagctccatt aaataattaa aacctagata ataagaaccg agcgagtgtc
     5821 tacgagcgat tgagcatcat caaaatttca cgctcgcctt ttccctgatt acacactccc
     5881 cttagcttaa taacgaaaga tacagagcat cccgaagggt gcgaactttg aagcttttgc
     5941 ttttgaaaag ccacgagcaa agcgagtgcc ggagttctgt ttttgatttt agaatttata
     6001 actgaaatta attaaaaact gccccacgaa gcgaggtacg agcttcaata gagtacgagc
     6061 tttagcgagt acctagggca gtttgcagtc ccctgctaaa aggcttttaa ttatttttaa
     6121 agcttttaat gcttttagac cctatgaaag cactgatatc agcgggtttc actctcaata
     6181 agcacacaaa ttctcttgta taagcacaca aattctcttg tataagcaca caaattctct
     6241 tgtataagca cacaaattct cttgatttac acacatatta tatgtagtgt ttaaatacac
     6301 attaataata acgtgtattt aatatgaaga atggtttagt tgtgaaagac aatgcattaa
     6361 taaacgccag ttataattta gaactaacag aacagcgttt aatcatgctg gcgataatta
     6421 atgcaaggga attaggacag ggcatcacgg cagatagcaa actagaaata catgctagtg
     6481 attatgcaaa gctctttaat gtatcaacag atgcatccta taaagctcta aaagaagctg
     6541 taaacaacct atttaataga cagtttagct atacagcaga atacaaaaaa acagggaaag
     6601 taggtgttgt tcgctctcgt tgggttagcc gtatttttta tgtagatgac ttagcgctat
     6661 tagaaattac tttcgcacct gacgtagtgc ctttaatcac tcgactagaa gaacatttta
     6721 cgaaatacga agccaaacaa gttgcacacc taaccagtaa gtacgctacc agactttatg
     6781 aattattaat cgcctggcgt gaggttggta aaacaccaat ttttgaacta caacaattac
     6841 gtaaaaattt aggtgttgaa gatgatgaat atcaacgtat gcatcatttt aaaaaccgtg
     6901 tattagacac agctattact cagatcaatg agcatacgga cataaaaact acttatgaac
     6961 agcataagca agggcgtacc atcactggtt tttcattcag atttaagcaa aaatcacagc
     7021 cgaaaattga aattaaacgt gacaccaata cccctgattt ttttgtcaaa atgaccgatg
     7081 cgcaacgtca tttatttgca aataaaatgt ctgaaatgcc cgaaatgtct aaatattcgc
     7141 gaggtacaga gagctttcaa cagtttgcta ttcgtatcgc cgacatgctt ttggaacctg
     7201 aaaaatttag agagctttat caatgtttag aaaaagcagg atttcaggca tagtccataa
     7261 aaatttattt tgcatttttt atttttcctt ttggtttggc tttaacaaga aatttctcac
     7321 ctaaagcctt tccttgttta aaagtaacaa cttctctttc gggaatatta atgaggtcgc
     7381 cagttttagg attacggccg attctttcag cacgtttttg aacggaaaaa gttccaaaat
     7441 cgactaattt aagactcttc tcttcaacta atgcttcagt aaatacttca agaacagaat
     7501 taagaataac tctggcttca tcttgagtta tatataattt aggagcaagt ttggcaatta
     7561 tatctgcttt attcatcgtt aattttcctc aatacttggt aaatcaaaaa gttttctatc
     7621 tcgatcttgt gttaaatatg tattgagatt agcgagtatt tttgttttct ctgtttcatc
     7681 ttccatttct ttaagcaaat aagaacctaa taatattttt ttgcgagttt cgtcttttct
     7741 ttgttgctct gaaattttct ttttttccct agcttcaatt gcctgttttt gagcttttaa
     7801 ttgttttaaa cgctcttctt gtttttcaat tttctgttct aaattttcaa tactcatact
     7861 ctaagatcat tccgaaataa ctcactcaat cataagcaca catgaattga aattcaaggt
     7921 gctatatgat atcgtggttt ttcccgaatg aaatgaaggg cgcacttatc cattgaaaaa
     7981 acctaacggt atttttcaat ggtaagcacg gtaggggata cccctacacc ccaaaccagt
     8041 ctatgtagac tggtgaaatt tggtaaacca aatttaagag caaaagcgaa atggcgatat
     8101 atcatttttc agtcaagaat ataagtagaa gtgacggacg atctgccgtt gcttgtgctg
     8161 cttatcgttc tgctgaaaaa ttgacatgcg actattacgg taaagaacaa gattacacaa
     8221 gaaaaatagg agtcgaacat acacaaatat atgcacccga aaatacaaat attaatttat
     8281 taaatagaca aaaattatgg aactcagttg agaaagttga gcgaagaaaa gatgcaactc
     8341 tagctagaga atttgaaatt gcttttccaa atgaacttaa tgcagagcaa cgaaaatcaa
     8401 tgctcgatga tctatgtaaa aagctcgttg aaaaatatgg tgcagttgtt gatgctgcaa
     8461 tacatgcacc acataaaaat agtggaagtg atgaacgaaa ttatcatgct catattatgt
     8521 ttacgacaag atcaattgat ctagaaacag gtgagttctc agcaaaaaaa tttcgtgatt
     8581 ttaataaaga agtgggaagt aaaacagtta aaaactggcg ctcatacttt gccgatttaa
     8641 ctaatttaca tttagaaaaa gcgggttttg atattcgtgt tgatcatcgt agtaataggg
     8701 cacgagggct agacctcgaa gcaacactac atgaaggctc aaaagtgact caacttcgac
     8761 gaatgaatat tgaaacagaa atcagtttaa aaaatgatgc gattaaacag cgtaacttat
     8821 tgagttcaat gcctgattta gagcatgaga tcattgcgac atcaaaactg ctgcaacagc
     8881 tcaaatttga gcaaagcaaa ttacaaacac aatcaagaga aagtgctttt gatgacattt
     8941 tgaatactgc ttcaagcaaa ttgacagaaa ttaatgagac ttttgacaaa ataactgaaa
     9001 atgttaacga aaacggaagt caaaaaaata tttttgatac gctcgactca agcatttcta
     9061 gtttgagcaa aaacgaattg ttttcaagct tgtctgactc tatcaacaat caagctgagc
     9121 atgagcgaca agctgagcat gaacgacaag ctgagcgtga gcgacaagct gagcatgaac
     9181 gacaagctga gcgtgaacga caagctgagc gtgagcgaca agctgagcgt gagcgacaag
     9241 tcgagcgtga gcaaactaga aataataact acacaccaga tttttagtta tttttggagt
     9301 tcgcatgagc gatcaagttt cagcaacatt gaaaacactt ttaaacacga tgcaactgct
     9361 ttcagaatca cttgaaaatg aaaagcaaca acatattgaa ttactgaaaa aacttaatag
     9421 tcatgtcagc aattcacaaa ctgaaattaa gaatgatttt tttgattttc taaacaaaat
     9481 tgagc
//
