LOCUS       NZ_CP031757             9294 bp    DNA     circular CON 08-JAN-2024
DEFINITION  Klebsiella aerogenes strain FDAARGOS_327 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP031757
VERSION     NZ_CP031757.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN06173340
            Assembly: GCF_003546885.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella aerogenes
  ORGANISM  Klebsiella aerogenes
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9294)
  AUTHORS   Campos,J., Goldberg,B., Tallon,L., Sadzewicz,L., Sengamalay,N.,
            Ott,S., Godinez,A., Nagaraj,S., Vavikolanu,K., Vyas,G., Nadendla,S.,
            Aluvathingal,J., Geyer,C., Nandy,P., Hobson,J. and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9294)
  AUTHORS   Campos,J., Goldberg,B., Tallon,L., Sadzewicz,L., Sengamalay,N.,
            Ott,S., Godinez,A., Nagaraj,S., Vavikolanu,K., Vyas,G., Nadendla,S.,
            Aluvathingal,J., Geyer,C., Nandy,P., Hobson,J. and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-AUG-2018) Center for Devices and Radiological Health,
            US Food and Drug Administration, 10903 New Hampshire Avenue, Silver
            Spring, MD 20993-0002, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 2.3.0, HGAP v. 3.0
            Genome Coverage                   :: 364.696x
            Sequencing Technology             :: PacBio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/08/2024 03:49:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,197
            CDSs (total)                      :: 5,074
            Genes (coding)                    :: 5,006
            CDSs (with protein)               :: 5,006
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 33 of 68
            Pseudo Genes (incomplete)         :: 34 of 68
            Pseudo Genes (internal stop)      :: 12 of 68
            Pseudo Genes (multiple problems)  :: 10 of 68
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031757.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Klebsiella aerogenes"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_327"
                     /isolation_source="Skin swab"
                     /host="Homo sapiens"
                     /culture_collection="FDA:FDAARGOS_327"
                     /db_xref="taxon:548"
                     /plasmid="unnamed1"
                     /geo_loc_name="USA: DC"
                     /collection_date="2015-01-11"
                     /collected_by="Children's National Hospital"
     gene            complement(join(8560..9294,1..1230))
                     /locus_tag="CEQ05_RS26945"
                     /old_locus_tag="CEQ05_26945"
     CDS             complement(join(8560..9294,1..1230))
                     /locus_tag="CEQ05_RS26945"
                     /old_locus_tag="CEQ05_26945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(2711..2860)
                     /locus_tag="CEQ05_RS26955"
                     /old_locus_tag="CEQ05_26955"
     CDS             complement(2711..2860)
                     /locus_tag="CEQ05_RS26955"
                     /old_locus_tag="CEQ05_26955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(2945..3202)
                     /locus_tag="CEQ05_RS26960"
                     /old_locus_tag="CEQ05_26960"
     CDS             complement(2945..3202)
                     /locus_tag="CEQ05_RS26960"
                     /old_locus_tag="CEQ05_26960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(3212..4897)
                     /locus_tag="CEQ05_RS26965"
                     /old_locus_tag="CEQ05_26965"
     CDS             complement(3212..4897)
                     /locus_tag="CEQ05_RS26965"
                     /old_locus_tag="CEQ05_26965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            5300..5719
                     /locus_tag="CEQ05_RS26975"
                     /old_locus_tag="CEQ05_26975"
     CDS             5300..5719
                     /locus_tag="CEQ05_RS26975"
                     /old_locus_tag="CEQ05_26975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            6025..6288
                     /locus_tag="CEQ05_RS26980"
                     /old_locus_tag="CEQ05_26980"
     CDS             6025..6288
                     /locus_tag="CEQ05_RS26980"
                     /old_locus_tag="CEQ05_26980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            6278..6577
                     /locus_tag="CEQ05_RS26985"
                     /old_locus_tag="CEQ05_26985"
     CDS             6278..6577
                     /locus_tag="CEQ05_RS26985"
                     /old_locus_tag="CEQ05_26985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(6639..7016)
                     /locus_tag="CEQ05_RS26990"
                     /old_locus_tag="CEQ05_26990"
     CDS             complement(6639..7016)
                     /locus_tag="CEQ05_RS26990"
                     /old_locus_tag="CEQ05_26990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            7085..7264
                     /locus_tag="CEQ05_RS26995"
                     /old_locus_tag="CEQ05_26995"
     CDS             7085..7264
                     /locus_tag="CEQ05_RS26995"
                     /old_locus_tag="CEQ05_26995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(7292..7822)
                     /locus_tag="CEQ05_RS27000"
                     /old_locus_tag="CEQ05_27000"
     CDS             complement(7292..7822)
                     /locus_tag="CEQ05_RS27000"
                     /old_locus_tag="CEQ05_27000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(7829..8560)
                     /locus_tag="CEQ05_RS27005"
                     /old_locus_tag="CEQ05_27005"
     CDS             complement(7829..8560)
                     /locus_tag="CEQ05_RS27005"
                     /old_locus_tag="CEQ05_27005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     BGC             1..9294
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          2030..2608
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(7833..8560)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 caggacgctc aggtcagcga cgttttccag cctagtgatc aaccccttca cgtccttttt
       61 cagggcctcc ggcagcgcgt acgccgccgc cagcacctgc tgaatgtttg ccccctgcgg
      121 aaactgctcc gcaatcagct tcgccgcttt ctgctcgctg atgcggtagt ggtccgccac
      181 gtcgccggtc tcgcccaggt taagcccggc aatcagcagg tttttcagcg cgtactggtc
      241 gagatcgcgg aacagattca gctgcgccgg tttccccggc cgcagatcca gcagggtgaa
      301 gtccggacag tgcgcccgga agacgtgcgg cgcccatgcg tcccctttgg ggtcgaagta
      361 caccaccgcg tccccgaaat cgcgtacgca gcgaatgagc gcgttggtgg ccatcacgct
      421 cttgccgctc ccgggcaggc cgaggatctg aatgttggtc ttgcgccagg tatcacgcgg
      481 aaccagcacc ggcttgccct gctcatcctt acccagaaac accgcctgct cctgccgggc
      541 ctgctccgag gaaaaatcgg ccagcgcatt aaccggtacc ggctccccga aatgcaggtg
      601 gcgcacgtcg gtcatctctc ctgtccgctg gctgctgcgc cggctctcct gattcagttt
      661 cgcgttcacc gcctcgtcag cagccgcaaa atgaccgtca agcagcagga acgccagcag
      721 ccgcgccaac acaatcccga cagccagccc gcccgcgcac caggcaatcc cgaacaggtt
      781 agccggctgc agcaggtaat aatctgcgtt tgcgtagagg tccggacgca ggacggtttc
      841 tccccagctc tcgataaaca cggcgacaac cagccccccc agaagggcca gaccggccgc
      901 gccggtcagc cagtacgcgt agttccagac atgtcgacgt gccctgacca tccgcccggg
      961 cgaatccagc gaggccagca ccgaaaatgg cgctggccgt ttattatcgc gcttatagcg
     1021 atcggcatac tcccgtcgct ccttatgact cagccccaca aaacgcatcc gtccggccca
     1081 aagttcagcc agaccgaaaa acaggccgat aactaggaaa gccccggcca gaccgtaata
     1141 ctcctggtac agccagctga cccacggata aatctgccgg gccagctccg gaatgtgcca
     1201 cttccaggca agcgaatccg tattaaacat gttctctctc cttcagacga tggtttgccg
     1261 gcgtgatgtg cagcccccgc tgcacaagcc gcggacatgc cccaaggcat ggcggcggcg
     1321 gtcacgtccg tggtgattgc gttcagcttt caccacggag gccagcctct ttccgcccca
     1381 tgcggaaaag gcgcagcccc ggaggaacaa cgagcacgcc ccagcgtgtg agaggaaaag
     1441 gcggcacccc agtgcggtct tttccggtgt tccggccccc gtcagagttc gccatagcga
     1501 gcggctgacc acccgcaaaa tcaggagcag ctttgctgct tcgccaggtg cgtccagcac
     1561 cgtggatttt tgtgggtggt caggcgtgag cctgacgggg gccgggtgaa tttctggcgt
     1621 ggccggcgtc cagccggacg gagccagaaa gagggggaga gaccgtgcgt cggtggcgtc
     1681 cagccagcgt aagcagggga tatccccctg aggtcagcca cgccctcgcg gggatgacct
     1741 gtatttctcc gtaaggagaa aaaagcaaca gagataggtt aacgtaaaat gttcagcgaa
     1801 aaaccgatat gattcaccta tcctggtaat ttattatcag ggaatataaa gacttaatca
     1861 ggggacaata tgccacatca gcgcgtccgg tgtccgtctt gtaggtgccg gggaaattgc
     1921 gcctcctcgc tcactcggtc gctacgctcc ggccgtgaga ctgcggcggg cgctgcggac
     1981 acatgcaaag ttacccacag attccgtgaa taagcagggg actaacatgt gaggcaaaac
     2041 ggcaaggcca cgcaggtggc gtttttccat aggctccgcc ctcctgactg agttcacata
     2101 aacagacgct ttttcggtgc atctgtggga gccggtggct caaccatgaa tcagtcagga
     2161 gtggcgaaac ccgacaggac ttaaagatca tcaccgtttc cgatgaatcg ctccctcttg
     2221 cgctctcctg ttccaaccct gccgtttccc ggatacctgt tccgcctttc tcccttgcgg
     2281 gaagtgtggc gctttctcat agctcacact ctggtatctc ggctcggtgt aggtcgttcg
     2341 ctccaagctg ggctgtaagc aagaaccccc cgttcagccc gactgctgcg ccttatccgg
     2401 taactgttca cttgagtcca acccggaaaa gcacgcaaaa cgccactggc agcagccatt
     2461 ggtaactggg agttcgcaga ggatttgttt agctaaacac gcggttgctc ttgaagtgtg
     2521 cgccaaagtc cggctacact ggaaggacag atttggttgc tgtgctctgc gaaagccagt
     2581 taccacggtt aagcagttcc ccaactgact taaccttcgt tcaaaccacc tccccaggtg
     2641 gttttttcgt ttacagggca aaagattacg cgcagaaaaa aaggatctca agaagatcct
     2701 ttgatctttt ctactgaacc gcgatccccg tcagttcaga ggaggacgat ggtgccaccg
     2761 ttccaccctg aacatcccgg atatagtttg cctgacatgc gaccagaaga aagcctgaaa
     2821 aaatcaatat aaaaagaaaa acaaccttta cctttttcat ataccttccc tgtatttaaa
     2881 aaccccggta ttcatccctg aacaccggaa gtctgtattt caaatcatcc ttgataactt
     2941 ttgcttacca gttaccatcc cggtaaacaa aggatacaaa gtaatcaaat ttactaatat
     3001 cgattacatt tttaaagtgt ggctgtaata tcgaaaccca tgatttttca acatcaaacc
     3061 aaccattatt aatattatcc tttaaaggca tccccagact ttcaatgaca gaaccatcat
     3121 caccgaagtc ttttgagtat tcaccacctt taaactcttc ggttttctta tcaaaccaat
     3181 gaatatgtaa tttaagcccc atatttacct cttaaagata ttttttaatg tttcgttttg
     3241 gatccggccc tttaacctgc ttacccgttt ttggatcgaa tgccccgagg tgttcgccat
     3301 cactggcgcg gtacccttca agctcaccgt gctgggaatc ccattcataa attttacgct
     3361 ttttatcacc ataccatcgg gcccgcttac caccaccacc ttgtttaggg gttttaggtt
     3421 taccctcttt caactctccc aaccccttaa tatcttcagt cttgggatca ggaaaataat
     3481 catggccgta atctttagtt cccttacgag gttttttctt ttcctcattt aatttatttt
     3541 ctgcatcctt cgcttttttc tccttttgtt tccggctctc catcgccccg gaaagcgcag
     3601 ccttatccct ggataaggat tcattcattt cgtttaaaga tgtctgggca gcttttaatt
     3661 tctcattctg attctgaata tccttatcaa gatagcgaac ctgatcctgc cacccggagc
     3721 catattcatg aggcgggtta taagtcacaa aatcatcttt atttgcctct gcctctttta
     3781 cctttttatc ggcttcctga acagcagccc ttgcaccggg gatcgccttc tctgtcgatg
     3841 caatgcgact gtttaaggtc gcaatatttt tatcttcagc atccagctca gctttcgctt
     3901 tatcatactc tcttttcagc ccctcttccg ggtgagcagc gtcccatgcc tgctggcgac
     3961 gcttttcttc ctccagacgc tgttttacct gtgccggagt aagaacatcc gtcaccgaca
     4021 catagaccgg tttctgtccg ctctctttcg ggaaacgaat aacggcttca cgggagttac
     4081 caccggccgt aaaaccagcc ggacgtgaat cacctttttc agcaataatg ccttttggcg
     4141 gggctttcgc ggccggaaca cctttaggta cgctcacctg cagagacggg agacccggaa
     4201 tcgacacact gaataccccc ggacgttttg tcggtttcgc atccaccaca ggaacactca
     4261 ttggccggcc ggtgacaacc gcaatatgct gccgctcgtc cttcacaata tccgccacac
     4321 gtttagtgac gctgaccgtc gcctggtcca gcggcaggga gctgaccggc gtctccgtta
     4381 ccgtgtctgc cggcaatgac gtcacgattt ttgacatcat tttcggatca tcttttgcta
     4441 tctcagaagg cagcactccg taaatcgcaa tcccccacag accaaactta aacggacctt
     4501 tcagggcagc cagcacatca gcaacagcgg ccgacaacgc atcgccggaa acggataaag
     4561 ccagtccttc agcccccgga gtggccaagg caggcagacc gaaggccatc gcggtggccg
     4621 aagactgtcc gccaccagag ctcccgctat gattgccgct gttaccgcca ttaccaccgg
     4681 gtttactccc gccgttacca aactcccccg ggttatagtt atgaatatcc ccgttaggtg
     4741 tatgcgtcgt accccagccc ggcccgctgt ttggatccgt accaccacct gatgaagggc
     4801 cacctttacc tgatgtaccg ttcacattcc cactggcctg accaccattg tgtcccagac
     4861 ctgaattacc cggacctcgt ccgtctccgc cactcatata cttttcctct ttgactttta
     4921 aaacaataaa ctaaaataaa atactgtaca tataaccact ggttttatat acagtataaa
     4981 aattacgctg ccttgttttt catgtcaagt ctgtaaattt gcgtttttgt gaaaatgatc
     5041 aaaaaaacag ccactcacac catgcgcaat cccctccaga tgcaacaaaa accagcacaa
     5101 acggcgccgt tctccggcct cagtatgttt tactgaaatc attatatgag ataccagaaa
     5161 gccccctccg ggacaggaaa agaaacgggg ggtctggttc gggttgttcg gtcactgaac
     5221 acggtcagaa actgatgata agatagcctg cggatatata actcaatgag aaaaaagaat
     5281 taaaggtaag gagacgctca tgagacgttc cggcagcaaa ctgtgtctta tcgccatgat
     5341 aacagcgaca gcaactctca ctgcctgtgc tccaaagggc agcgtggaac agcatacccg
     5401 gcattacgta tatgcttcag atgacggttt tgatcccaat ttttccaccc agaaagctga
     5461 cacaacacga atgatggtgc cttttttccg gcagttctgg gatatgggcg caaaggataa
     5521 agcgaccgga aaatcacgga gtgatgtgca gcaacgcatt cagcagtttc acagtcagga
     5581 atttttaaac tcactccaag gcacaacaca atttgcgggt accgattacc gcagcaaaga
     5641 cctcacaccg aaaaaatcaa ggctactggc tgacaccatt tcagctgttt atctcgatgg
     5701 ctatgaaggc agacagtaag tggatttacc ataacgcgtc attacgcgca ccgctcagac
     5761 gggctcaggg cgtttccggc ggctacggga taaaacaggc aacaaccccc ccggaaaact
     5821 gccggaaacg cgcccgataa attttatcct aatgcatgcc tatgcacgca actgcatggc
     5881 atatgttttg acgtaaaatg gatgccgtaa gccctttttt accgactttc tgcttcatca
     5941 gcctgactga cacgaccata ttctttcaga ccgccccctg ctaaacttcc ttcatattgc
     6001 cgcattaacc cgggaggctc cgcaatgagc aacactacac actacgaaaa cgccaacttt
     6061 cttcgggaac tggctgaaag cctgccccgc atactgccgg aaggtggccc ggacaaagct
     6121 gcgctgttgc agcgactggc taacgaagaa ctggcccagg cagagtatga agatcaggtt
     6181 cgcgccaaag tgaccgccgc ccgtgctgac acgcgtccgg gtatgaccac ggaacaactc
     6241 cgccagcgcc tgcatggccg ttatcaggaa ctgcgcgatg ccgtatgacg tggaatggaa
     6301 gcagggagcc atcgaggatg taacgacgct gtttgactat atcgcggaaa attcatccct
     6361 gtgggatgcg cagaacgtta ccgaccgggt tctcgctgcg gcggacaaac tggccgactt
     6421 cccgcgactc tatgaagtgg actcacgcta tggcgaggac gttcgccgga tcagtctgat
     6481 gggacagcat gtcctctatg atgttgatga ccagaccaga aaagtccggg ttctggccgt
     6541 ggtcggccag cgccagaatc cccatattgt tctctaataa ccggtgacgg ggacgcaatt
     6601 cattgcgtgg ccgtcgccgg ttggacaagc acagcgcgtc agcgttttcc ccacggccac
     6661 caccggcgcg gtgttccggc cggggtctct gctgtctccg gtttgtgttc cagcagtctc
     6721 atggactgca tttcctgccg tagcccggcc acctcctccc tgagtgcttt tatctccgcg
     6781 atcaacgcgt cggaggccat tttttcagtc tcacccgaca gtctcaactc gtcccgctcg
     6841 tgagtctcat cctgtcttaa ctcaccgtac acccggataa gctcgctggt atccaccacc
     6901 cggccgccat cagcttccgt acggtatgat acgcggcctt tcgccatatc ccgatacagg
     6961 gaacttcggg ctttacccgt cagttccgtc gcctgtctca ccgtcaccca cgccattgtc
     7021 tcaccccgct atttttgaga cagtatacct gacaggcgca caccatgccc ggaaggaaag
     7081 aatcatgaca aaacaggaaa aaacagccct caatatggct aaatttatta aggagcagtc
     7141 gctgctattg ctcgataaac tgaatgagct ggatatggat accccggccg acatgtgcga
     7201 gcggctacac gaggatgcgg aaacactctg gcaggtgatg cgggataagc tcggggagga
     7261 ataacagcac cggcatggcc ggtgctggca tttatttttt gccgaacggc caccaccggc
     7321 gggcaggttt gtcctccggc agttcaggta ccggcacgtt aaaatagcgg ctgttatatt
     7381 cccgcatcag ctccgctttc agcttctcgt tcaccgcgct ttccccgtgc cgctcactca
     7441 ccacgtcaat catcgcgtta atctgctccg gtgagcactt cccggcatca accacctgca
     7501 caccgttctc gatggcgaac cgctccacct tgcgatagag gtaatcacac agcttcattc
     7561 ctgtgggttt gttccgttcc cattgcggat ttttaccagt gaaaaagtac gtggcttttt
     7621 cgtcgctgtt gagccgctcg tcatacatcc cgatggattt catcatcgcc agatgctggg
     7681 cccggtcgac aaaacagaaa acatacgccc cggtctgcca ggcgagcacc accatatctt
     7741 ccagatgctc gctggtcggc atgatgcagc gctcgccgtt ccggtcctcc gcgtcttcaa
     7801 taaataccat gtacagcgcc ataatccctc actccgttgt cataaattta aagcacgcaa
     7861 acaaccgttc acgatccagc tctgccgttt tgcgggcctc gccggtctgt gggttcacga
     7921 tttcatccac cgacaggatt gcccgctgca ccctgacctg cgtcgcccgg tccgggcaga
     7981 tgtaccagat ttcatcgatg ccgttagctt tgcggttgaa cagatacccg gacaccactt
     8041 cctgataccg gcgacggctc ttgacggtgc gctccacctc aaacgccacc gttttaccgt
     8101 ccagctccgc cagggcgtcc ggcactttca tgcctttaag actcagacgg tgcagaatgc
     8161 gccagccggt ggcccctctg gcttccatat caaggcgcag ggattgcacg gccagccggt
     8221 gcggcagatg tgctgccgac acccttgacg gctgaaacgg aataacatcc gccagcggtt
     8281 cgtcctcgtc gaacgagaac gccacgccat gcggcgtcag cccccacacg ctgacctgac
     8341 ggccgtccac cggatatttg gtccggacca gcagcccttt cgccaccagg ctgtcgagga
     8401 agcggtagac cggctgcacc gccgcaatcc ccagccgccg cgcaaccagc tccgccgtgg
     8461 aacacagctc ttcccgcaac cagcgcaggg tcagccgggt tttctccgcg ttccgcgcct
     8521 gtcgtttcgc gtggctgacg ttgtacagct ccagcgccat cagtaaatcc ccgcaaaatc
     8581 atcatccgct ttcggcccgc cgccgtcggc cgggggccgg aactccgcca ggggatcggt
     8641 tttcgccagc accgggaaac gctgcaacgg gatttcccgg cgctcaaccc gcagcggact
     8701 gctgaacgcc atccgggcca cacccagccc ggtcatgacc gcgaacccgt ccggcaggtg
     8761 ttgcagggtg ttcacgtcaa acagcggccg cgcctccttc tggatgaagc tgtccccgct
     8821 gatatgctcc acgttccccg cctcccggct ggcacggcgg cgctccacgt ccaccctgat
     8881 ttccccggtc tgccccgccg cccactgcgc ggactccagg ctggccgccc ggtaaaacca
     8941 gcggatcggc gtgttatcca gtaccgtggt tttcacaaat tcagcgggca gatcctgccc
     9001 gcactgcccg aaatcgccca gcgactggtg cgcgagcaac agattgcagt cccggctgcg
     9061 cagcgtcccc agtgcgttca gtacatactt cgacagcaga tatttaattt catcgagcat
     9121 cacgctgacg tgtggccact cccggaactc gtcccgcgca atgatgattt gcgcgcagcg
     9181 ggcaaacagc attttttgca cacggatcac cgcctcgtcg tccatcgagc cgataacgta
     9241 caggcagccg ccgccgttga taatccccgc cacatcgatg ccactgtccg tctg
//
